Comparative study of mutations in SNP loci of K-RAS, hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer

Table 1 Clinical data of the three groups of patients

Group		Number	Sex (n)		Age (yr)
		(n)	Male	Female	Range	mean ± SD
Observation group (neoplastic polyps)	Tubular adenoma	85	54	31	27-68	39.2 ± 7.6
	Villous adenoma	17	9	8	24-65	36.5 ± 11.2
	Mixed adenoma	18	8	10	29-66	37.4 ± 10.9
Control group I (colorectal cancer)	Tubular adenocarcinoma	42	24	18	37-72	44.6 ± 11.3
	Mucinous adenocarcinoma	27	17	10	34-70	40.2 ± 9.6
	Papillary adenocarcinoma	8	5	3	33-58	41.1 ± 10.3
	Other types1	3	3	0	45-52	48.3 ± 7.1
Control group II (normal)		40	26	14	22-55	34.6 ± 6.3

¹Other types include undifferentiated carcinoma.