Original Article
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 28, 2014; 20(40): 14865-14874
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14865
Table 1 Inclusion and exclusion criteria
Inclusion criteria
Age ≥ 18 yr and ≤ 65 yr
Typical symptoms: regurgitation and heartburn
Atypical symptoms: belching, chest pain, pharyngeal burning, foreign body sensations, chronic unexplained pharyngitis, hoarseness, bronchitis, and asthma
Proton pump inhibitor therapy-positive
Written informed consent
Exclusion criteria
Nasopharynx or upper esophagus obstruction
Esophageal varices and severe esophageal mucosal erosion
Severe esophageal motility disorder (e.g., achalaisa, scleroderma, diabetes mellitus, autonomic or peripheral neuropathy, and myopathy)
In vivo congenital gastrointestinal malformation, gastrointestinal obstruction, perforation, stricture, or fistula
A recent history of stomach surgery or gastrointestinal bleeding (within the past 6 mo)
A history of bleeding tendency and taking anticoagulant drugs in the long term
Any implanted electrical device, such as cardiac pacemakers
Allergy to the polymer materials
Various acute enteritis, severe ischemic disease, or radioactive colitis
Unstable cardiopathy, psychotic diseases arrhythmia cordis, or being uncooperative