Serum concentrations of insulin-like growth factor-binding protein 5 in Crohn’s disease

Table 2 Clinical and biochemical parameters of Crohn’s disease patients and healthy controls

	Crohn’s disease (n = 42)	Healthy controls (n = 20)	P value1
CDAI	87.0 (52-138)	-
ESR (mm/h)	35.5 (17.0-48)	12.0 (10.5-14.5)	< 0.001
CRP (mg/dL)	0.6 (0.3-1.5)	0.2 (0.1-0.3)	< 0.001
Hb (g/dL)	13.0 (11.8-13.9)	14.0 (12.9-15)	0.0063
WBC (× 103/mm3)	7.7 (5.9-9.2)	6.2 (5.3-7.9)	0.0356
PLT (× 103/mm3)	309.5 (245-359)	240.0 (229.0-243.5)	0.0001
Alb (g/L)	3.9 (3.7-4.4)	4.7 (4-5)	< 0.001
IGFBP-5 (ng/mL)	7.2 (5.5-11.3)	11.3 (8.0-44.6)	0.0019

¹P value from Mann-Whitney test. Results are given as median. IQR: Interquartile range; CDAI: Crohn’s Disease Activity Index; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; Hb: Hemoglobin; WBC: White blood cell count; PLT: Platelet count; Alb: Albumin; IGFBP-5, Insulin-like growth factor-binding protein 5.