Synchronous vs sequential laparoscopic cholecystectomy for cholecystocholedocholithiasis

Table 1 Basic characteristics and intraoperative and postoperative parameters of patients who underwent synchronous and sequential operations

	Synchronous group	Sequential group	P value
Total patients	70	80
M/F ratio	46/24	53/27	0.54
Mean age, yr	59.0 (38-75)	56.6 (36-74)	0.18
ASA score (I-II/III)	62/8	70/10	0.52
Symptoms
Abdominal pain	59 (84.3)	72 (90.0)	0.22
Jaundice	51 (71.4)	62 (77.5)	0.32
Nausea or vomiting	39 (55.7)	47 (58.8)	0.42
Mean serum bilirubin, mg/dL	5.4 (0.5-24)	5.9 (0.6-27)	0.68
Mean γ-GGT, μ/dL	116.2 (27-342)	122.8 (35-396)	0.70
MRCP diagnosis
Mean diameter of CBDS, mm	9.7 (7-21)	9.2 (6-20)	0.47
Stone number (single/multi)	49/21	56/24	0.57
Mean operative time, min	112.1 ± 30.8	104.9 ± 18.2	0.08
Success rate
Endoscopic sphincterotomy	70 (100)	77 (96.3)	0.15
Laparoscopic cholecystectomy	69 (98.6)	80 (100)	0.74
Major complications rate
Acute pancreatitis	1 (1.4)	5 (6.3)	0.14
Hyperamylasemia	1 (1.4)	8 (10)	0.03
Bleeding/perforation/infection	0 (0)	0 (0)
Hospital stay, d	3 (2-6)	4.5 (3-12)	< 0.001

Data are expressed as absolute n (%) or median (range). M: Male; F: Female; γ-GGT: γ-glutamyl transpeptidase; ASA: American Society of Anaesthesiologists; MRCP: Magnetic resonance cholangiopancreatography; CBDS: Common bile duct stone.