Celiac disease: Prevalence, diagnosis, pathogenesis and treatment

Table 6 Operating characteristics of serological markers to detect the celiac disease in adults[178] (adapted)

Serological tests	Sensitivity	Specificity	Predictive value		Likelihood ratio
	95% CI (%)	95% CI (%)	Positive	Negative	Positive	Negative
IgG AGA	57-78	71-87	0.2-0.9	0.4-0.9	1.96-6	0.25-0.61
IgA AGA	55-100	71-100	0.3-1.0	0.7-1.0	1.89-∞	0-0.63
IgA EMA	86-100	98-100	0.98-1.0	0.8-0.95	43-∞	0-0.14
IgA TGA	77-100	91-100	> 0.9	> 0.95	8.55-∞	0-0.25
IgA TGA and EMA	98-100	98-100	> 0.9	> 0.95	49-∞	0-0.02

IgG: Immunoglobulin G; IgA: Immunoglobulin A; AGA: Anti-gliadin antibodies; EMA: Endomysial; TGA: Transglutaminase.