Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner

Figure 1 Osteopontin splice variants are expressed at different levels in the liver of hepatocellular carcinoma patients and in various cell lines. A: Schematic representation of the three osteopontin (OPN) splice variants; B: Polymerase chain reaction (PCR) performed on cDNA from different cell types shows varying distribution patterns of OPN mRNA; C: PCR performed on cDNA taken from patient hepatocellular carcinoma (HCC), and its surrounding tissue indicates altered OPN splice variant expression in HCC. GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.