Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells

Figure 4 Treatment with cinnamon extract inhibits APC-dependent T-cell proliferation. APC-dependent T-cell proliferation was measured. MHCII⁺ APCs (A) and CD11c⁺ dendritic cells (DCs) (B) were pre-pulsed in the absence or presence of cinnamon extract for 24 h. Then, they were co-cultured with CD4⁺ T cells isolated from Do11.10 mice in the presence of Ova peptide. After 72 h co-culture, T-cell proliferation was measured by [H³]-thymidine incorporation assay. Error bars indicated SD. ^aP < 0.05, ^bP < 0.005, ^cP < 0.001. Data are representative of three independent experiments.