Decreased accumulation of ultrasound contrast in the liver of nonalcoholic steatohepatitis rat model

Figure 5 Decreased phagocytic activity in Kupffer cells from methionine choline-deficient dietrats compared to Kupffer cells from control rats. Control and methionine choline-deficient diet (MCDD) rats were injected with fluoresceinisothiocyanate (FITC)-labeled latex beads and Kupffer cells (KCs) were isolated 1 h later. KCs which had phagocytosed FITC-labeled latex beads were counted by flow cytometry and changes in the phagocytic activity were compared between control and MCDD KCs. Note that there was an almost 50% decrease in phagocytic activity in KCs from MCDD, compared to KCs from controls. ^aP < 0.05 vs control.