Original Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 7, 2011; 17(37): 4191-4198
Published online Oct 7, 2011. doi: 10.3748/wjg.v17.i37.4191
Figure 2
Figure 2 Histological changes of methionine choline-deficient diet-fed rat liver (hematoxylin eosin x 200). Extremely large vesicle fat deposits in almost the entire lobules were detected even as early as two weeks after the start of the methionine choline-deficient diet. By 8 wk, spotty necrosis was dispersed and by 16 wk, there was fibrosis extending from the central vein. A: Control; B: Two weeks methionine choline-deficient (MCD); C: Four weeks MCD; D: Eight weeks MCD; E: Twelve weeks MCD; F: Sixteen weeks MCD.