Survival and prognostic factors in hepatitis B virus-related acute-on-chronic liver failure

Table 2 Factors affecting prognosis based on single-factor analysis

	Cases	Median time (mo)	1-yr survival rate (%)	χ2 value	P value
Age (yr)
20-45	88	6.7	69.9	9.047	0.003
> 45	102	2.5	46.5
Fundamental disease
Cirrhosis	120	2.6	49.1	8.026	0.005
No cirrhosis	69	8.4	71.8
Antiviral therapy
No	49	1.8	42.5	8.050	0.005
Yes	141	5.5	62.7
Electrolyte disturbances
No	46	11.8	84.1	14.397	< 0.001
Yes	144	2.6	49.3
HE grade
No	126	7.1	70.7	38.596	< 0.001
I-II	53	1.6	35.1
III-IV	11	1.5	9.1
SBP
No	127	6.0	64.3	5.345	0.021
Yes	63	2.5	44.3
HRS
No	174	5.7	60.9	18.403	< 0.001
Yes	16	0.9	20.8
PTA groups (%)
< 20	18	1.2	22.2	22.619	< 0.001
20-30	77	5.1	58.6
30-40	66	6.7	70.6
> 40	29	3.3	47.1

HE: Hepatic encephalopathy; SBP: Spontaneous bacterial peritonitis; HRS: Hepatorenal syndrome; PTA: Prothrombin activity.