Review
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2011; 17(18): 2288-2301
Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2288
Table 3 Comparison between silybin phytosome and silymarin pharmacokinetics in patients with liver cirrhosis[44]
Silybin phytosomeSilymarin
(360 mg)(336 mg)
Cmax (ng/mL)860 ± 166b83 ± 15
Tmax (h)2.7 ± 0.7b2.6 ± 2.1
/2 (h)3.3 ± 0.7b2.6 ± 0.4
AUC515 ± 665b262 ± 39
Total bioavailability252 ± 39b19 ± 23