Review
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2011; 17(18): 2288-2301
Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2288
Table 1 Pharmacokinetics of silybin phytosome and silymarin in healthy participants[38-43]
Silybin phytosomeSilymarin
Peak concentration (ng/mL)298 ± 96102 ± 22a
Time of peak (h)1.6 ± 0.31.4 ± 0.3
Mean residence time (h)3.6 ± 0.43.5 ± 0.4
AUC (ng/mL/h)881 ± 207257 ± 66b