Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 21, 2011; 17(11): 1501-1506
Published online Mar 21, 2011. doi: 10.3748/wjg.v17.i11.1501
Table 2 HER-2 protein expression and HER-2 gene amplification in gastric carcinoma tissue samples
Clinicopathologic datanHER-2 (IHC)
P valueHER-2 (FISH)
P value
Pos%Amp%
Sex
Male951414.7NS1010.5NS
Female50816.0816.0
Age (yr)
> 60681014.7NS710.3NS
≤ 60771215.61114.3
Diameter of the tumor (cm)
> 5851517.6NS1214.1NS
≤ 560711.7610.0
Location
Cardia or fundus of stomach55814.5712.7
Body of stomach39512.8NS410.3NS
Sinus ventriculi/ostium pyloricum51917.6713.7
Differentiation
Well36616.7513.9
Moderately44511.4NS49.1NS
Pooly/undifferentiated651116.9913.8
Serosa invasion
Positive1072018.7< 0.051715.9< 0.05
Negative3825.312.7
Lymph node metastasis
Positive912022.0< 0.051819.8< 0.05
Negative5423.700.0
Distant metastasis
Positive111090.9< 0.05981.8< 0.05
Negative134129.086.0
TNM stage
 I + II6734.5< 0.0522.99< 0.05
III + IV781924.41620.5
Histopathological classification(Lauren)
Intestinal861922.11719.8
Diffuse3725.4< 0.0500.0< 0.05
Non classified2214.514.5