An antioxidant resveratrol significantly enhanced replication of hepatitis C virus

Figure 5 Sequential change of luciferase activity of OS6 cells after addition of interferon (IFN). A: IFN was added for the indicated duration and the ratio to the luciferase activity at time 0 was shown. Statistical significance (^aP < 0.05, ^bP < 0.01) is shown below: at 24 h 0 vs 1^a, 2^b, 4^b, 10^b and 20^b; at 48 h, 0 vs 1^b, 2^b, 4^b, 10^b and 20^b; 1 vs 2^b, 4^b, 10^b and 20^b; 20 vs 2^b, 4^b and 10^b; at 72 h, 0 vs 1^b, 2^b, 4^b, 10^b and 20^b; 1 vs 2^a; 1 vs 4^b, 10^b and 20^b; 2 vs 4^b, 10^b and 20^b; 4 vs 10^b and 20^b; 10 vs 20^b; B: Luciferase activity after addition of RVB and IFN for 72 h was shown as the ratio to that without antiviral agents. ^aP < 0.05, ^bP < 0.01.