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Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Dec 14, 2009; 15(46): 5770-5775
Published online Dec 14, 2009. doi: 10.3748/wjg.15.5770
Table 3 CLE classification of patterns in colorectal lesions
GradingVessel architectureCrypt architecture
NormalHexagonal, honeycomb appearance that presents a network of capillaries outlining the stroma surrounding the luminal openings of the cryptsRegular luminal openings and distribution of crypts covered by a homogeneous layer of epithelial cells, including goblet cells
RegenerationHexagonal, honeycomb appearance with no increase or only a slight increase in the number of capillariesStar-shaped luminal crypt openings or focal aggregation of regular-shaped crypts with a regular or reduced amount of goblet cells
NeoplasiaDilated and distorted vessels with increased leakage; irregular architecture, with little or no orientation to the adjoining tissueRidge-lined irregular epithelial layer with loss of crypts and goblet cells; irregular cell architecture, with little or no mucin