Etiopathogenesis of primary sclerosing cholangitis

Table 3 Autoantibody prevalence in primary sclerosing cholangitis

Antibody	Prevalence (%)
Anti-nuclear antibody (ANA)	7-77
Anti-smooth muscle antibody (ASMA)	13-20
Anti-endothelial cell antibody (AECA)	35
Anti-cardiolipin antibody	4-66
Thyroperoxidase	7-16
Thyroglobulin	4
Rheumatoid factor	15

Anti-mitochondrial antibody is only rarely detected in PSC (< 10%). This is useful in differentiating PSC from primary biliary cirrhosis (PBC). Data taken from Angulo et al[12].