Anastomotic disruption after large bowel resection

Table 3 Clinical studies utilizing staples for fashioning colorectal anastomosis

Investigators	Study design	Number of patients	Leak rate (%)
Detry et al[49]	Prospective	1 000	3.5
Griffen et al[50]	Prospective	75	2.7
Cohen et al[51]	Prospective	26	3.8
Laitinen et al[52]	Prospective	39	5.3
Baran et al[53]	Retrospective	104	2.8
Karanjia et al[54]	Prospective	276	11
Hansen et al[55]	Prospective	615	1.5
Memon et al[56]	Prospective	218	3