Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 21, 2006; 12(15): 2328-2334
Published online Apr 21, 2006. doi: 10.3748/wjg.v12.i15.2328
Table 5 Treatment regimens for eosinophilic esophagitis
Treatment optionProtocol
Elimination DietAvoidance of allergen depending on results of food allergy testing
Oligoantigenic diet: Eliminate large number of suspected foods and allow limited nutritionally balanced diet
Elemental diet: Various formulas such as Neocate (free amino acids, corn syrup solids, medium chain triglycerides)
Topical corticosteroids: Mayo Clinic protocolFluticasone 220 μg puffer 4 puffs BID x 6 wk, swallowed, no spacer
Rinse mouth with water and spit out
No food or drink for 3 h after dose
Systemic (oral) corticosteroidsMethylprednisolone 1.5 mg/kg per day (or equivalent dose prednisone)
Divide into bid dosing for 4 wk then taper over 6 wk
MontelukastInitial dose: 10 mg po daily
Titration: Dose up to 100 mg/d depending on symptoms and tolerance
Maintenance: Once symptoms relieved titrate down to minimal dose to maintain remission (usually 20 - 40 mg/d)
Mepolizumab10 mg/kg iv infusion q 4 wk x 3 doses