Exogenous acid fibroblast growth factor inhibits ischemia-reperfusion-induced damage in intestinal epithelium via regulating P53 and P21WAF-1 expression

Table 3 Effect of aFGF on mRNA contents of P53 and P21WAF-1 genes in intestinal mucosa after ischemia-reperfusion (n = 6, mean±SD, %)

Groups	P53		P21WAF-1
	R group	A group	R group	A group
C group	23.5±6.0	22.4±2.5	26.7±2.0	24.6±4.1
I group	38.9±5.1a	34.8±4.2a	32.6±2.0a	31.7±2.0a
15 min after reperfusion	53.9±3.9a	45.8±10.7a	33.4±2.3a	24.0±3.4c
30 min after reperfusion	34.0±4.4a	41.9±5.2ac	23.3±4.2	22.9±2.0
1 h after reperfusion	48.5±3.2a	44.7±5.4a	24.8±2.3	23.8±3.2
2 h after reperfusion	46.7±5.4a	41.3±6.3a	26.5±2.7	24.9±3.0
6 h after reperfusion	48.8±5.2a	38.3±4.7ac	30.8±3.0a	20.9±2.6c
12 h after reperfusion	51.0±4.5a	34.1±4.8ac	32.7±1.6a	21.9±2.8c
24 h after reperfusion	55.3±7.3a	56.9±5.3a	28.8±3.1	28.5±5.0
48 h after reperfusion	56.4±8.3a	61.0±4.0a	29.0±2.3	28.9±3.8

^aP<0.05 vs C group;

^cP<0.05 vs R group at matched time point.