Effect of pegylated interferon alpha 2b plus ribavirin treatment on plasma transforming growth factor-&beta;1, metalloproteinase-1, and tissue metalloproteinase inhibitor-1 in patients with chronic hepatitis C

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Nov 21, 2005 (publication date) through Apr 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2005; 11(43): 6833-6838
Published online Nov 21, 2005. doi: 10.3748/wjg.v11.i43.6833

Table 4 Values of biochemical indices of liver injury during treatment (0, 24, and 48 wk) and 24 wk after its completion (wk 72) in both groups

	Weeks after the beginning of treatment
	0	24	48	72
Bilirubin	Non-responders	1±0.1	1±0.1	0.7±0.1	0.9±0.1
(mg%)	Responders	1.1±0.1	1.1±0.1	0.9±0.1	1.0±0.1
ALT(U/L)	Non-responders	101±15	40±6^c	55±20	98±18^a
	Responders	96±13	35±9^c	24±5^c	22±2^c
AST(U/L)	Non-responders	58±8	30±4^c	34±6^a^c	64±10^a
	Responders	48±6	26±3^c	20±1^c	19±2^c

^aP<0.05 responders vs non-responders,

^cP<0.05 vs baseline.

Citation: Flisiak R, Jaroszewicz J, Łapiński TW, Flisiak I, Prokopowiczi D. Effect of pegylated interferon alpha 2b plus ribavirin treatment on plasma transforming growth factor-β1, metalloproteinase-1, and tissue metalloproteinase inhibitor-1 in patients with chronic hepatitis C. World J Gastroenterol 2005; 11(43): 6833-6838
URL: https://www.wjgnet.com/1007-9327/full/v11/i43/6833.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i43.6833