Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma

Figure 1 Skp2, p27 and PTEN expression in different gastric tissues (DAB and hematoxylin stain). A: Positive Skp2 in nuclei of intestinal metaplasia and dysplasia cells (original magnification ×400); B: Positive Skp2 in nuclei of well-differentiated gastric carcinoma cells (original magnification ×400); C: Positive Skp2 in nuclei of poorly differentiated gastric carcinoma cells (original magnification ×100); D: Positive Skp2 in lymphatic metastatic gastric carcinoma cells (original magnification ×100); E: Positive p27 in nuclei of well-differentiated gastric carcinoma cells (original magnification ×400); F: Positive PTEN in nuclei of well-differentiated gastric carcinoma cells (original magnification ×400).