Alpha-fetoprotein stimulated the expression of some oncogenes in human hepatocellular carcinoma Bel 7402 cells

Figure 4 Effects of AFP (20 mg/L), HSA (20 mg/L), anti-AFP antibody (40 mg/L), and AFP (20 mg/L) + anti-AFP antibody (40 mg/L) on the expression of c-jun mRNA in human hepato-cellular carcinoma Bel 7402 cells analyzed by Northern blot after 6 h treatment. A: Autoradiogram of Northern blot. Lane 1: control group; Lane 2: HSA treated group; Lane 3: AFP treated group; Lane 4: anti-AFP antibody treated group; Lane 5: AFP + anti-AFP antibody treated group. B: Densitometric intensity of absorbance (IOD) of c-jun mRNA expression in Bel 7402 cells. The data were selected from 3 independent experiments.