Acute liver failure: A progress report

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Oct 1, 1995 (publication date) through Jan 23, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 1, 1995; 1(1): 4-8
Published online Oct 1, 1995. doi: 10.3748/wjg.v1.i1.4

Table 4 Possible predisposing factors for acute liver failure

Etiologic agents
Viruses	various hepatotropic viruses
	superinfection of hepatotropic viruses
	variants of a hepatotropic virus (mutants)
Chemicals
Miscellaneous
Host factors
Hyperfunction of cellular immunity
Hyperfunction of antibody production → immune complexes
Endogenous endotoxemia
Deficient phagocytosis of reticuloendothetial system
Activation of macrophages	overproduction of TNF-α and IL-1
	release of leukotrienes
	release of superoxides
Liver regeneration failure	overproduction of regeneration-suppressing factors
	disorders in cell receptors and signal transduction
Apoptosis

Citation: Pan BR, Yang SF, Ma LS. Acute liver failure: A progress report. World J Gastroenterol 1995; 1(1): 4-8
URL: https://www.wjgnet.com/1007-9327/full/v1/i1/4.htm
DOI: https://dx.doi.org/10.3748/wjg.v1.i1.4