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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2015; 21(31): 9367-9372
Published online Aug 21, 2015. doi: 10.3748/wjg.v21.i31.9367
Published online Aug 21, 2015. doi: 10.3748/wjg.v21.i31.9367
Fluid resuscitation in acute pancreatitis: Normal saline or lactated Ringer's solution?
Michal Lipinski, Grazyna Rydzewska, Department of Gastroenterology, Central Clinical Hospital of The Ministry of Interior, 02-507 Warsaw, Poland
Alicja Rydzewska-Rosolowska, Department of Nephrology and Transplantation, Medical University of Bialystok, 15-540 Bialystok, Poland
Andrzej Rydzewski, Department of Internal Medicine and Nephrology, Central Clinical Hospital of The Ministry of Interior, 02-507 Warsaw, Poland
Andrzej Rydzewski, Grazyna Rydzewska, The Faculty of Health Sciences, UJK, 25-369 Kielce, Poland
Author contributions: Lipinski M and Rydzewska G designed the study; Lipinski M performed the research; Lipinski M, Rydzewska-Rosolowska A and Rydzewski A contributed new reagents or analytic tools; Lipinski M analysed the data; Lipinski M wrote the paper; and all authors have read and approved the final version to be published.
Conflict-of-interest statement: Authors declare no conflict of interest.
Data sharing statement: The technical appendix, statistical code, and dataset are available from the corresponding author at michal7lipinski@yahoo.com. Consent was not obtained, but the presented data are anonymized, and the risk of identification is low. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Michal Lipinski, MD, PhD, Department of Gastroenterology, Central Clinical Hospital of The Ministry of Interior, 137 Woloska Street, 02-507 Warsaw, Poland. michal7lipinski@yahoo.com
Telephone: +48-22-5081240 Fax: +48-22-5081040
Received: December 5, 2014
Peer-review started: December 5, 2014
First decision: January 22, 2015
Revised: February 28, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: August 21, 2015
Peer-review started: December 5, 2014
First decision: January 22, 2015
Revised: February 28, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: August 21, 2015
Core Tip
Core tip: To date, only a handful of studies have focused on the effect of Ringer’s solution in the treatment of acute pancreatitis (AP). We believe that our findings could be of interest to the readers because they may allow for a more reliable review of a complex area of fluid resuscitation in the setting of AP compared with existing studies. These results were mainly achieved by applying the modified Atlanta score in our study, which includes “end points” focused on the final AP treatment outcome rather than only on changes in a single laboratory parameter and clinical signs.