| 1 |
Ferreira PMP, Sousa LQ, Sousa RWR, Rodrigues DJ, Monção Filho EDS, Chaves MH, Vieira-Júnior GM, Rizzo MDS, Filgueiras LA, Mendes AN, Lima DJB, Pessoa C, Sousa JMCE, Rodrigues ACBDC, Soares MBP, Bezerra DP. Toxic profile of marinobufagin from poisonous Amazon toads and antitumoral effects on human colorectal carcinomas. J Ethnopharmacol 2023;:116406. [PMID: 36965547 DOI: 10.1016/j.jep.2023.116406] [Reference Citation Analysis]
|
| 2 |
Zhao W, Li G, Zhang Q, Chen M, He L, Wu Z, Zhang Y, Fan M, Liang Y, Zhang W, Zeng F, Deng F. Cardiac glycoside neriifolin exerts anti-cancer activity in prostate cancer cells by attenuating DNA damage repair through endoplasmic reticulum stress. Biochem Pharmacol 2023;209:115453. [PMID: 36792037 DOI: 10.1016/j.bcp.2023.115453] [Reference Citation Analysis]
|
| 3 |
Xu J, Lin S, Hu H, Xing Q, Geng J. Tumor-Targeting Polymer–Drug Conjugate for Liver Cancer Treatment In Vitro. Polymers 2022;14:4515. [DOI: 10.3390/polym14214515] [Reference Citation Analysis]
|
| 4 |
El-Seedi HR, Yosri N, El-Aarag B, Mahmoud SH, Zayed A, Du M, Saeed A, Musharraf SG, El-Garawani IM, Habib MR, Tahir HE, Hegab MM, Zou X, Guo Z, Efferth T, Khalifa SAM. Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads. Molecules 2022;27:6586. [PMID: 36235123 DOI: 10.3390/molecules27196586] [Reference Citation Analysis]
|
| 5 |
Soumoy L, Ghanem GE, Saussez S, Journe F. Bufalin for an innovative therapeutic approach against cancer. Pharmacol Res 2022;184:106442. [PMID: 36096424 DOI: 10.1016/j.phrs.2022.106442] [Reference Citation Analysis]
|
| 6 |
Li G, An T, Li Y, Yue J, Huang R, Huang J, Liang J, Yao W, Huang L, Chen Y, Zhang R, Ji A, Duan L. Transcriptome Analysis and Identification of the Cholesterol Side Chain Cleavage Enzyme BbgCYP11A1 From Bufo bufo gargarizans. Front Genet 2022;13:828877. [PMID: 35480310 DOI: 10.3389/fgene.2022.828877] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
|
| 7 |
Peng W, Xu Y, Feng F, Gu C, Wang Z, Han D, Zhou X, He H. Meta-Analysis of Therapy of Cinobufacini Capsule Adjunct with First-Line Platinum-Based Chemotherapy for the Treatment of Advanced NSCLC. Evid Based Complement Alternat Med 2021;2021:5596415. [PMID: 34471417 DOI: 10.1155/2021/5596415] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
|
| 8 |
Kumavath R, Paul S, Pavithran H, Paul MK, Ghosh P, Barh D, Azevedo V. Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics. Biomolecules 2021;11:1275. [PMID: 34572488 DOI: 10.3390/biom11091275] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
|
| 9 |
Gu R, Zhang Q. Effects of low-dose bufalin combined with hydroxycamptothecin on human castration-resistant prostate cancer xenografts in nude mice. Exp Ther Med 2021;22:1015. [PMID: 34373701 DOI: 10.3892/etm.2021.10447] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
|
| 10 |
Gao L, Zhang L, He F, Chen J, Zhao M, Li S, Wu H, Liu Y, Zhang Y, Ping Q, Hu L, Qiao H. Surfactant Assisted Rapid-Release Liposomal Strategies Enhance the Antitumor Efficiency of Bufalin Derivative and Reduce Cardiotoxicity. Int J Nanomedicine 2021;16:3581-98. [PMID: 34079251 DOI: 10.2147/IJN.S313153] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
|
| 11 |
Li FJ, Hu JH, Ren X, Zhou CM, Liu Q, Zhang YQ. Toad venom: A comprehensive review of chemical constituents, anticancer activities, and mechanisms. Arch Pharm (Weinheim) 2021;354:e2100060. [PMID: 33887066 DOI: 10.1002/ardp.202100060] [Cited by in Crossref: 12] [Cited by in F6Publishing: 14] [Article Influence: 6.0] [Reference Citation Analysis]
|
| 12 |
Huang HC, Chang WT, Lee MS, Chen HY, Chen YH, Lin CC, Lin MK. Three bufadienolides induce cell death in the human lung cancer cell line CL1-5 mainly through autophagy. Bioorg Med Chem Lett 2021;31:127715. [PMID: 33246109 DOI: 10.1016/j.bmcl.2020.127715] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
|
| 13 |
Ayogu JI, Odoh AS. Prospects and Therapeutic Applications of Cardiac Glycosides in Cancer Remediation. ACS Comb Sci 2020;22:543-53. [PMID: 32786321 DOI: 10.1021/acscombsci.0c00082] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 2.7] [Reference Citation Analysis]
|
| 14 |
Zhong Y, Zhao C, Wu WY, Fan TY, Li NG, Chen M, Duan JA, Shi ZH. Total synthesis, chemical modification and structure-activity relationship of bufadienolides. Eur J Med Chem 2020;189:112038. [PMID: 31945667 DOI: 10.1016/j.ejmech.2020.112038] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
|
| 15 |
Yang D, Gao P, Tian C, Sheng Y. Gompertz tracking of the growth trajectories of the human-liver-cancer xenograft-tumors in nude mice. Comput Methods Programs Biomed 2020;191:105412. [PMID: 32114418 DOI: 10.1016/j.cmpb.2020.105412] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
|
| 16 |
Veklich TO, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Labyntseva RD, Shkrabak OA, Tsymbalyuk OV, Rodik RV, Kalchenko VI, Kosterin SO, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;, Institute of High Technologies, Taras Shevchenko National University of Kyiv, Ukraine;, Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kyiv, Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kyiv, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;. Inhibition of Na(+),K(+)-ATPase and activation of myosin ATPase by calix[4]arene C-107 cause stimulation of isolated smooth muscle contractile activity. Ukr Biochem J 2020;92:21-30. [DOI: 10.15407/ubj92.01.021] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
|
| 17 |
Schimmel K, Jung M, Foinquinos A, José GS, Beaumont J, Bock K, Grote-Levi L, Xiao K, Bär C, Pfanne A, Just A, Zimmer K, Ngoy S, López B, Ravassa S, Samolovac S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F, Kreutzer FP, Kenneweg F, Leonardy J, Hobuß L, Santer L, Do QT, Geffers R, Braesen JH, Schmitz J, Brandenberger C, Müller DN, Wilck N, Kaever V, Bähre H, Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J, González A, Thum T. Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction. Circulation 2020;141:751-67. [PMID: 31948273 DOI: 10.1161/CIRCULATIONAHA.119.042559] [Cited by in Crossref: 31] [Cited by in F6Publishing: 32] [Article Influence: 10.3] [Reference Citation Analysis]
|
| 18 |
Garcia IJP, de Oliveira GC, de Moura Valadares JM, Banfi FF, Andrade SN, Freitas TR, Dos Santos Monção Filho E, Lima Santos H, Júnior GMV, Chaves MH, de Jesus Rodrigues D, Sanchez BAM, Varotti FP, Barbosa LA. New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells. Steroids 2019;152:108490. [PMID: 31499071 DOI: 10.1016/j.steroids.2019.108490] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 3.3] [Reference Citation Analysis]
|
| 19 |
Cheng CS, Wang J, Chen J, Kuo KT, Tang J, Gao H, Chen L, Chen Z, Meng Z. New therapeutic aspects of steroidal cardiac glycosides: the anticancer properties of Huachansu and its main active constituent Bufalin. Cancer Cell Int 2019;19:92. [PMID: 31011289 DOI: 10.1186/s12935-019-0806-1] [Cited by in Crossref: 30] [Cited by in F6Publishing: 32] [Article Influence: 7.5] [Reference Citation Analysis]
|
| 20 |
Oliveira AFD, Castoldi L, Vieira Junior GM, Monção Filho EDS, Chaves MH, Rodrigues DDJ, Sugui MM. Evaluation of antimutagenic and cytotoxic activity of skin secretion extract of Rhinella marina and Rhaebo guttatus (Anura, Bufonidae). Acta Amaz 2019;49:145-51. [DOI: 10.1590/1809-4392201801751] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.8] [Reference Citation Analysis]
|
| 21 |
Lan YL, Lou JC, Jiang XW, Wang X, Xing JS, Li S, Zhang B. A research update on the anticancer effects of bufalin and its derivatives. Oncol Lett 2019;17:3635-40. [PMID: 30915168 DOI: 10.3892/ol.2019.10062] [Cited by in Crossref: 6] [Cited by in F6Publishing: 10] [Article Influence: 1.5] [Reference Citation Analysis]
|
| 22 |
Su E, Chu Y, Chueh F, Ma Y, Peng S, Huang W, Liao C, Huang A, Chung J. Bufalin Induces Apoptotic Cell Death in Human Nasopharyngeal Carcinoma Cells through Mitochondrial ROS and TRAIL Pathways. Am J Chin Med 2019;47:237-57. [DOI: 10.1142/s0192415x19500125] [Cited by in Crossref: 19] [Cited by in F6Publishing: 21] [Article Influence: 4.8] [Reference Citation Analysis]
|
| 23 |
Zhang Y, Dong Y, Melkus MW, Yin S, Tang SN, Jiang P, Pramanik K, Wu W, Kim S, Ye M, Hu H, Lu J, Jiang C. Role of P53-Senescence Induction in Suppression of LNCaP Prostate Cancer Growth by Cardiotonic Compound Bufalin. Mol Cancer Ther 2018;17:2341-52. [PMID: 30166403 DOI: 10.1158/1535-7163.MCT-17-1296] [Cited by in Crossref: 20] [Cited by in F6Publishing: 21] [Article Influence: 4.0] [Reference Citation Analysis]
|
| 24 |
Qi J, Zulfiker AHM, Li C, Good D, Wei MQ. The Development of Toad Toxins as Potential Therapeutic Agents. Toxins (Basel) 2018;10:E336. [PMID: 30127299 DOI: 10.3390/toxins10080336] [Cited by in Crossref: 34] [Cited by in F6Publishing: 35] [Article Influence: 6.8] [Reference Citation Analysis]
|
| 25 |
Huang H, Zhang W. Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+-ATPase. Oncol Lett 2018;16:3826-32. [PMID: 30127995 DOI: 10.3892/ol.2018.9142] [Cited by in Crossref: 2] [Cited by in F6Publishing: 8] [Article Influence: 0.4] [Reference Citation Analysis]
|
| 26 |
Pan Z, Xie Y, Bai J, Lin Q, Cui X, Zhang N. Bufalin suppresses colorectal cancer cell growth through promoting autophagy in vivo and in vitro. RSC Adv 2018;8:38910-8. [DOI: 10.1039/c8ra06566g] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 1.4] [Reference Citation Analysis]
|
| 27 |
Wang Y, Feng L, Piao B, Zhang P. Review on Research about Traditional Chinese Medicine in Cancer Stem Cell. Evid Based Complement Alternat Med 2017;2017:4505194. [PMID: 29234398 DOI: 10.1155/2017/4505194] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.7] [Reference Citation Analysis]
|
| 28 |
Chou HY, Chueh FS, Ma YS, Wu RS, Liao CL, Chu YL, Fan MJ, Huang WW, Chung JG. Bufalin induced apoptosis in SCC‑4 human tongue cancer cells by decreasing Bcl‑2 and increasing Bax expression via the mitochondria‑dependent pathway. Mol Med Rep 2017;16:7959-66. [PMID: 28983595 DOI: 10.3892/mmr.2017.7651] [Cited by in Crossref: 17] [Cited by in F6Publishing: 18] [Article Influence: 2.8] [Reference Citation Analysis]
|
| 29 |
Wang LP, Zhao YN, Sun X, Gao RL. Effects of bufalin on up-regulating methylation of Wilm's tumor 1 gene in human erythroid leukemic cells. Chin J Integr Med 2017;23:288-94. [PMID: 28364352 DOI: 10.1007/s11655-017-2404-1] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
|
| 30 |
Sousa LQ, Machado KD, Oliveira SF, Araújo LD, Monção-Filho ED, Melo-Cavalcante AA, Vieira-Júnior GM, Ferreira PM. Bufadienolides from amphibians: A promising source of anticancer prototypes for radical innovation, apoptosis triggering and Na+/K+-ATPase inhibition. Toxicon 2017;127:63-76. [PMID: 28069354 DOI: 10.1016/j.toxicon.2017.01.004] [Cited by in Crossref: 48] [Cited by in F6Publishing: 50] [Article Influence: 8.0] [Reference Citation Analysis]
|
| 31 |
Chen H, Sun D, Peng Y, Kao P, Wu Y. Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells. Innate Immun 2017;23:54-66. [DOI: 10.1177/1753425916676347] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
|
| 32 |
Wu SH, Bau DT, Hsiao YT, Lu KW, Hsia TC, Lien JC, Ko YC, Hsu WH, Yang ST, Huang YP, Chung JG. Bufalin induces apoptosis in vitro and has Antitumor activity against human lung cancer xenografts in vivo. Environ Toxicol 2017;32:1305-17. [PMID: 27444971 DOI: 10.1002/tox.22325] [Cited by in Crossref: 29] [Cited by in F6Publishing: 32] [Article Influence: 4.1] [Reference Citation Analysis]
|
| 33 |
Zhang YZ, Chen X, Fan XX, He JX, Huang J, Xiao DK, Zhou YL, Zheng SY, Xu JH, Yao XJ, Liu L, Leung EL. Compound Library Screening Identified Cardiac Glycoside Digitoxin as an Effective Growth Inhibitor of Gefitinib-Resistant Non-Small Cell Lung Cancer via Downregulation of α-Tubulin and Inhibition of Microtubule Formation. Molecules 2016;21:374. [PMID: 26999101 DOI: 10.3390/molecules21030374] [Cited by in Crossref: 16] [Cited by in F6Publishing: 19] [Article Influence: 2.3] [Reference Citation Analysis]
|
| 34 |
Wang Q, Li C, Zhu Z, Teng Y, Che X, Wang Y, Ma Y, Wang Y, Zheng H, Liu Y, Qu X. miR-155-5p antagonizes the apoptotic effect of bufalin in triple-negative breast cancer cells. Anti-Cancer Drugs 2016;27:9-16. [DOI: 10.1097/cad.0000000000000296] [Cited by in Crossref: 14] [Cited by in F6Publishing: 17] [Article Influence: 2.0] [Reference Citation Analysis]
|
| 35 |
Pan G, Bao Y, Xu J, Liu T, Liu C, Qiu Y, Shi X, Yu H, Jia T, Yuan X, Yuan Z, Yin P, Cao Y. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer. RSC Adv 2016;6:42109-19. [DOI: 10.1039/c6ra05236c] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 1.3] [Reference Citation Analysis]
|
| 36 |
Tian X, Dai S, Sun J, Jiang S, Sui C, Meng F, Li Y, Fu L, Jiang T, Wang Y, Su J, Jiang Y. Bufalin Induces Mitochondria-Dependent Apoptosis in Pancreatic and Oral Cancer Cells by Downregulating hTERT Expression via Activation of the JNK/p38 Pathway. Evid Based Complement Alternat Med 2015;2015:546210. [PMID: 26783410 DOI: 10.1155/2015/546210] [Cited by in Crossref: 11] [Cited by in F6Publishing: 15] [Article Influence: 1.4] [Reference Citation Analysis]
|
| 37 |
Wang J, Chen C, Wang S, Zhang Y, Yin P, Gao Z, Xu J, Feng D, Zuo Q, Zhao R, Chen T. Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways. Gastroenterol Res Pract. 2015;2015:457193. [PMID: 26770191 DOI: 10.1155/2015/457193] [Cited by in Crossref: 23] [Cited by in F6Publishing: 28] [Article Influence: 2.9] [Reference Citation Analysis]
|
| 38 |
Zhang Y, Jin H, Li X, Zhao J, Guo X, Wang J, Guo Z, Zhang X, Tao Y, Liu Y, Chen D, Liang X. Separation and characterization of bufadienolides in toad skin using two-dimensional normal-phase liquid chromatography×reversed-phase liquid chromatography coupled with mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2016;1026:67-74. [PMID: 26621782 DOI: 10.1016/j.jchromb.2015.11.015] [Cited by in Crossref: 20] [Cited by in F6Publishing: 21] [Article Influence: 2.5] [Reference Citation Analysis]
|
| 39 |
Efuet ET, Ding XP, Cartwright C, Pan Y, Cohen L, Yang P. Huachansu mediates cell death in non-Hodgkin's lymphoma by induction of caspase-3 and inhibition of MAP kinase. Int J Oncol 2015;47:592-600. [PMID: 26062471 DOI: 10.3892/ijo.2015.3044] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.0] [Reference Citation Analysis]
|
| 40 |
Choi MJ, Kim KN, Lee JE, Suh JW, Kim SC, Kwon KR, Cho SH. Effects of Sumsu (Bufonis venenum) Pharmacopuncture Treatment on Depression in Mice. J Pharmacopuncture 2014;17:27-33. [PMID: 25780696 DOI: 10.3831/KPI.2014.17.013] [Cited by in Crossref: 3] [Cited by in F6Publishing: 7] [Article Influence: 0.4] [Reference Citation Analysis]
|
| 41 |
Xie RF, Li ZC, Chen PP, Zhou X. Bufothionine induced the mitochondria-mediated apoptosis in H22 liver tumor and acute liver injury. Chin Med 2015;10:5. [PMID: 25806084 DOI: 10.1186/s13020-015-0033-1] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 1.8] [Reference Citation Analysis]
|
| 42 |
Pan Y, Rhea P, Tan L, Cartwright C, Lee HJ, Ravoori MK, Addington C, Gagea M, Kundra V, Kim SJ, Newman RA, Yang P. PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Invest New Drugs 2015;33:271-9. [PMID: 25476893 DOI: 10.1007/s10637-014-0190-6] [Cited by in Crossref: 29] [Cited by in F6Publishing: 32] [Article Influence: 3.2] [Reference Citation Analysis]
|
| 43 |
Wu SH, Wu TY, Hsiao YT, Lin JH, Hsu SC, Hsia TC, Yang ST, Hsu WH, Chung JG. Bufalin induces cell death in human lung cancer cells through disruption of DNA damage response pathways. Am J Chin Med 2014;42:729-42. [PMID: 24871662 DOI: 10.1142/S0192415X14500475] [Cited by in Crossref: 22] [Cited by in F6Publishing: 24] [Article Influence: 2.4] [Reference Citation Analysis]
|
| 44 |
Xue R, Han N, Ye C, Wang L, Yang J, Wang Y, Yin J. The cytotoxic activities of cardiac glycosides from Streptocaulon juventas and the structure-activity relationships. Fitoterapia 2014;98:228-33. [PMID: 25128424 DOI: 10.1016/j.fitote.2014.08.008] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.0] [Reference Citation Analysis]
|
| 45 |
Jiang L, Zhao MN, Liu TY, Wu XS, Weng H, Ding Q, Shu YJ, Bao RF, Li ML, Mu JS, Wu WG, Ding QC, Cao Y, Hu YP, Shen BY, Tan ZJ, Liu YB. Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells. Tumour Biol 2014;35:10931-41. [PMID: 25085580 DOI: 10.1007/s13277-014-1911-3] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 2.3] [Reference Citation Analysis]
|
| 46 |
Deng L, Hu L, Peng Q, Yang X, Bai L, Yiu A, Li Y, Tian H, Ye W, Zhang D. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chemico-Biological Interactions 2014;219:184-94. [DOI: 10.1016/j.cbi.2014.06.003] [Cited by in Crossref: 27] [Cited by in F6Publishing: 28] [Article Influence: 3.0] [Reference Citation Analysis]
|
| 47 |
Zhu YR, Xu Y, Fang JF, Zhou F, Deng XW, Zhang YQ. Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation. Biochem Biophys Res Commun 2014;451:112-8. [PMID: 25068992 DOI: 10.1016/j.bbrc.2014.07.077] [Cited by in Crossref: 33] [Cited by in F6Publishing: 31] [Article Influence: 3.7] [Reference Citation Analysis]
|
| 48 |
Wu SH, Hsiao YT, Chen JC, Lin JH, Hsu SC, Hsia TC, Yang ST, Hsu WH, Chung JG. Bufalin alters gene expressions associated DNA damage, cell cycle, and apoptosis in human lung cancer NCI-H460 cells in vitro. Molecules 2014;19:6047-57. [PMID: 24828377 DOI: 10.3390/molecules19056047] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 1.6] [Reference Citation Analysis]
|
| 49 |
Zhang ZJ, Yang YK, Wu WZ. Bufalin attenuates the stage and metastatic potential of hepatocellular carcinoma in nude mice. J Transl Med 2014;12:57. [PMID: 24581171 DOI: 10.1186/1479-5876-12-57] [Cited by in Crossref: 25] [Cited by in F6Publishing: 31] [Article Influence: 2.8] [Reference Citation Analysis]
|
| 50 |
Chueh FS, Chen YY, Huang AC, Ho HC, Liao CL, Yang JS, Kuo CL, Chung JG. Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways. Environ Toxicol 2014;29:21-9. [PMID: 21922632 DOI: 10.1002/tox.20769] [Cited by in Crossref: 29] [Cited by in F6Publishing: 33] [Article Influence: 3.2] [Reference Citation Analysis]
|
| 51 |
Zhai XF, Fang FF, Liu Q, Meng YB, Guo YY, Chen Z. MiR-181a contributes to bufalin-induced apoptosis in PC-3 prostate cancer cells. BMC Complement Altern Med 2013;13:325. [PMID: 24267199 DOI: 10.1186/1472-6882-13-325] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 2.1] [Reference Citation Analysis]
|
| 52 |
Chang Y, Zhao Y, Zhan H, Wei X, Liu T, Zheng B. Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells. Tumor Biol 2014;35:1075-82. [DOI: 10.1007/s13277-013-1143-y] [Cited by in Crossref: 22] [Cited by in F6Publishing: 23] [Article Influence: 2.2] [Reference Citation Analysis]
|
| 53 |
Chen Y, Lu H, Hsu S, Kuo C, Chang S, Lin J, Wu P, Liu J, Lee C, Chung J, Chang J. Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways: Bufalin Inhibits Migration and Invasion in SK-Hep1 Cells. Environ Toxicol 2015;30:74-82. [DOI: 10.1002/tox.21896] [Cited by in Crossref: 46] [Cited by in F6Publishing: 52] [Article Influence: 4.6] [Reference Citation Analysis]
|
| 54 |
Huang H, Cao Y, Wei W, Liu W, Lu SY, Chen YB, Wang Y, Yan H, Wu YL. Targeting poly (ADP-ribose) polymerase partially contributes to bufalin-induced cell death in multiple myeloma cells. PLoS One. 2013;8:e66130. [PMID: 23762475 DOI: 10.1371/journal.pone.0066130] [Cited by in Crossref: 13] [Cited by in F6Publishing: 15] [Article Influence: 1.3] [Reference Citation Analysis]
|
| 55 |
Zheng Z, Cho WC, Xu L, Wang J, Sze DM. Lessons learnt from evidence-based approach of using chinese herbal medicines in liver cancer. Evid Based Complement Alternat Med 2013;2013:656351. [PMID: 23818930 DOI: 10.1155/2013/656351] [Cited by in Crossref: 4] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
|
| 56 |
Moreno Y Banuls L, Urban E, Gelbcke M, Dufrasne F, Kopp B, Kiss R, Zehl M. Structure-activity relationship analysis of bufadienolide-induced in vitro growth inhibitory effects on mouse and human cancer cells. J Nat Prod 2013;76:1078-84. [PMID: 23706005 DOI: 10.1021/np400034d] [Cited by in Crossref: 47] [Cited by in F6Publishing: 48] [Article Influence: 4.7] [Reference Citation Analysis]
|
| 57 |
Salvador JA, Carvalho JF, Neves MA, Silvestre SM, Leitão AJ, Silva MM, Sá e Melo ML. Anticancer steroids: linking natural and semi-synthetic compounds. Nat Prod Rep 2013;30:324-74. [PMID: 23151898 DOI: 10.1039/c2np20082a] [Cited by in Crossref: 180] [Cited by in F6Publishing: 186] [Article Influence: 18.0] [Reference Citation Analysis]
|
| 58 |
Yang F, Ren L, Zhuo L, Ananda S, Liu L. Involvement of oxidative stress in the mechanism of triptolide-induced acute nephrotoxicity in rats. Experimental and Toxicologic Pathology 2012;64:905-11. [DOI: 10.1016/j.etp.2011.03.013] [Cited by in Crossref: 43] [Cited by in F6Publishing: 44] [Article Influence: 3.9] [Reference Citation Analysis]
|
| 59 |
Xie XB, Yin JQ, Wen LL, Gao ZH, Zou CY, Wang J, Huang G, Tang QL, Colombo C, He WL, Jia Q, Shen JN. Critical role of heat shock protein 27 in bufalin-induced apoptosis in human osteosarcomas: a proteomic-based research. PLoS One 2012;7:e47375. [PMID: 23091618 DOI: 10.1371/journal.pone.0047375] [Cited by in Crossref: 31] [Cited by in F6Publishing: 40] [Article Influence: 2.8] [Reference Citation Analysis]
|
| 60 |
Yin P, Wang Y, Qiu Y, Hou L, Liu X, Qin J, Duan Y, Liu P, Qiu M, Li Q. Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity. Int J Nanomedicine 2012;7:3961-9. [PMID: 22888239 DOI: 10.2147/IJN.S32063] [Cited by in Crossref: 6] [Cited by in F6Publishing: 27] [Article Influence: 0.5] [Reference Citation Analysis]
|
| 61 |
Zhang DM, Liu JS, Tang MK, Yiu A, Cao HH, Jiang L, Chan JY, Tian HY, Fung KP, Ye WC. Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis. Eur J Pharmacol 2012;692:19-28. [PMID: 22841670 DOI: 10.1016/j.ejphar.2012.06.045] [Cited by in Crossref: 73] [Cited by in F6Publishing: 76] [Article Influence: 6.6] [Reference Citation Analysis]
|
| 62 |
Hsiao YP, Yu CS, Yu CC, Yang JS, Chiang JH, Lu CC, Huang HY, Tang NY, Yang JH, Huang AC, Chung JG. Triggering apoptotic death of human malignant melanoma a375.s2 cells by bufalin: involvement of caspase cascade-dependent and independent mitochondrial signaling pathways. Evid Based Complement Alternat Med 2012;2012:591241. [PMID: 22719785 DOI: 10.1155/2012/591241] [Cited by in Crossref: 16] [Cited by in F6Publishing: 27] [Article Influence: 1.5] [Reference Citation Analysis]
|
| 63 |
Elbaz HA, Stueckle TA, Tse W, Rojanasakul Y, Dinu CZ. Digitoxin and its analogs as novel cancer therapeutics. Exp Hematol Oncol 2012;1:4. [PMID: 23210930 DOI: 10.1186/2162-3619-1-4] [Cited by in Crossref: 88] [Cited by in F6Publishing: 88] [Article Influence: 8.0] [Reference Citation Analysis]
|
| 64 |
Xie CM, Chan WY, Yu S, Zhao J, Cheng CH. Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation. Free Radic Biol Med 2011;51:1365-75. [PMID: 21763418 DOI: 10.1016/j.freeradbiomed.2011.06.016] [Cited by in Crossref: 177] [Cited by in F6Publishing: 190] [Article Influence: 14.8] [Reference Citation Analysis]
|
| 65 |
Lu C, Wang W, Ma N, Cui Y, Li X, Zhou Y. Anticancer peptide from Chinese toad (Bufo Bufo Gargarizans) skin enhanced sensitivity to 5-Fu in hepatocarcinoma cells (HepG2). Clin Oncol Cancer Res 2011;8:149-54. [DOI: 10.1007/s11805-011-0574-8] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
|
| 66 |
Dong Y, Yin S, Li J, Jiang C, Ye M, Hu H. Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway. Apoptosis 2011;16:394-403. [PMID: 21259053 DOI: 10.1007/s10495-011-0573-5] [Cited by in Crossref: 57] [Cited by in F6Publishing: 60] [Article Influence: 4.8] [Reference Citation Analysis]
|
| 67 |
Sun L, Chen T, Wang X, Chen Y, Wei X. Bufalin Induces Reactive Oxygen Species Dependent Bax Translocation and Apoptosis in ASTC-a-1 Cells. Evid Based Complement Alternat Med 2011;2011:249090. [PMID: 19592481 DOI: 10.1093/ecam/nep082] [Cited by in Crossref: 23] [Cited by in F6Publishing: 28] [Article Influence: 1.9] [Reference Citation Analysis]
|
| 68 |
Yang F, Zhuo L, Ananda S, Sun T, Li S, Liu L. Role of reactive oxygen species in triptolide-induced apoptosis of renal tubular cells and renal injury in rats. J Huazhong Univ Sci Technolog Med Sci 2011;31:335-41. [PMID: 21671174 DOI: 10.1007/s11596-011-0377-4] [Cited by in Crossref: 20] [Cited by in F6Publishing: 20] [Article Influence: 1.7] [Reference Citation Analysis]
|
| 69 |
Qi F, Inagaki Y, Gao B, Cui X, Xu H, Kokudo N, Li A, Tang W. Bufalin and cinobufagin induce apoptosis of human hepatocellular carcinoma cells via Fas- and mitochondria-mediated pathways. Cancer Sci. 2011;102:951-958. [PMID: 21288283 DOI: 10.1111/j.1349-7006.2011.01900.x] [Cited by in Crossref: 115] [Cited by in F6Publishing: 122] [Article Influence: 9.6] [Reference Citation Analysis]
|
| 70 |
Wang PS, Yeh J, Yu C, Wang S. An Evidence-based Perspective of Bufo Gargarizans (Asiatic Toad) for Cancer Patients. Evidence-based Anticancer Materia Medica 2011. [DOI: 10.1007/978-94-007-0526-5_18] [Reference Citation Analysis]
|
| 71 |
Qi F, Li A, Inagaki Y, Kokudo N, Tamura S, Nakata M, Tang W. Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor. Int Immunopharmacol 2011;11:342-9. [PMID: 21185919 DOI: 10.1016/j.intimp.2010.12.007] [Cited by in Crossref: 160] [Cited by in F6Publishing: 173] [Article Influence: 12.3] [Reference Citation Analysis]
|
| 72 |
Zhu Z, Yu Y, Wang K, Li E, Liu Y, Liu Y. [Effect of Bufalin on proliferation and apoptosis of human non-small cell lung cancer A549 cell]. Zhongguo Fei Ai Za Zhi 2010;13:841-5. [PMID: 20840810 DOI: 10.3779/j.issn.1009-3419.2010.09.01] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
|
| 73 |
Liu Y, Wang P, Sun C, Feng N, Zhou W, Yang Y, Tan R, Chen Z, Wu S, Zhao J. Wheat germ agglutinin-grafted lipid nanoparticles: Preparation and in vitro evaluation of the association with Caco-2 monolayers. International Journal of Pharmaceutics 2010;397:155-63. [DOI: 10.1016/j.ijpharm.2010.06.030] [Cited by in Crossref: 35] [Cited by in F6Publishing: 38] [Article Influence: 2.7] [Reference Citation Analysis]
|
| 74 |
Perne A, Muellner MK, Steinrueck M, Craig-Mueller N, Mayerhofer J, Schwarzinger I, Sloane M, Uras IZ, Hoermann G, Nijman SM. Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis. PLoS One. 2009;4:e8292. [PMID: 20016840 DOI: 10.1371/journal.pone.0008292] [Cited by in Crossref: 60] [Cited by in F6Publishing: 63] [Article Influence: 4.3] [Reference Citation Analysis]
|
| 75 |
Lu CX, Nan KJ, Nie YL, Hai YN, Jiao M. Delisheng, a Chinese medicinal compound, exerts anti-proliferative and pro-apoptotic effects on HepG2 cells through extrinsic and intrinsic pathways. Mol Biol Rep 2010;37:3407-12. [PMID: 20012371 DOI: 10.1007/s11033-009-9930-7] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 1.2] [Reference Citation Analysis]
|
| 76 |
Lu CX, Nan KJ, Lei Y. Agents from amphibians with anticancer properties. Anticancer Drugs 2008;19:931-9. [PMID: 18827558 DOI: 10.1097/CAD.0b013e3283139100] [Cited by in Crossref: 64] [Cited by in F6Publishing: 71] [Article Influence: 4.6] [Reference Citation Analysis]
|
| 77 |
Mijatovic T, Ingrassia L, Facchini V, Kiss R. Na+/K+-ATPase alpha subunits as new targets in anticancer therapy. Expert Opin Ther Targets 2008;12:1403-17. [PMID: 18851696 DOI: 10.1517/14728222.12.11.1403] [Cited by in Crossref: 60] [Cited by in F6Publishing: 62] [Article Influence: 4.3] [Reference Citation Analysis]
|
| 78 |
Chen A, Yu J, Zhang L, Sun Y, Zhang Y, Guo H, Zhou Y, Mitchelson K, Cheng J. Microarray and biochemical analysis of bufalin-induced apoptosis of HL-60 Cells. Biotechnol Lett. 2009;31:487-494. [PMID: 19039527 DOI: 10.1007/s10529-008-9888-x] [Cited by in Crossref: 24] [Cited by in F6Publishing: 22] [Article Influence: 1.6] [Reference Citation Analysis]
|
| 79 |
Yu CH, Kan SF, Pu HF, Jea Chien E, Wang PS. Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells. Cancer Sci. 2008;99:2467-2476. [PMID: 19037992 DOI: 10.1111/j.1349-7006.2008.00966.x] [Cited by in Crossref: 117] [Cited by in F6Publishing: 123] [Article Influence: 7.8] [Reference Citation Analysis]
|
| 80 |
Prassas I, Diamandis EP. Novel therapeutic applications of cardiac glycosides. Nat Rev Drug Discov. 2008;7:926-935. [PMID: 18948999 DOI: 10.1038/nrd2682] [Cited by in Crossref: 432] [Cited by in F6Publishing: 446] [Article Influence: 28.8] [Reference Citation Analysis]
|
