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For: Federico A, Dallio M, Loguercio C. Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. Molecules 2017;22:E191. [PMID: 28125040 DOI: 10.3390/molecules22020191] [Cited by in Crossref: 132] [Cited by in F6Publishing: 112] [Article Influence: 33.0] [Reference Citation Analysis]
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7 Drouet S, Tungmunnithum D, Lainé É, Hano C. Gene Expression Analysis and Metabolite Profiling of Silymarin Biosynthesis during Milk Thistle (Silybum marianum (L.) Gaertn.) Fruit Ripening. Int J Mol Sci 2020;21:E4730. [PMID: 32630801 DOI: 10.3390/ijms21134730] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 5.0] [Reference Citation Analysis]
8 de Souza Santos V, Peters B, Côco LZ, Alves GM, de Assis ALEM, Nogueira BV, Meyrelles SS, Porto ML, Vasquez EC, Campagnaro BP, Pereira TMC. Silymarin protects against radiocontrast-induced nephropathy in mice. Life Sciences 2019;228:305-15. [DOI: 10.1016/j.lfs.2019.04.061] [Cited by in Crossref: 7] [Cited by in F6Publishing: 9] [Article Influence: 3.5] [Reference Citation Analysis]
9 Lu C, Li X, Liang X, Zhang X, Yin T, Gou J, He H, Zhang Y, Tang X. Liver Targeting Albumin-Coated Silybin-Phospholipid Particles Prepared by Nab™ Technology for Improving Treatment Effect of Acute Liver Damage in Intravenous Administration. AAPS PharmSciTech 2019;20. [DOI: 10.1208/s12249-019-1504-y] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
10 Kuznietsova H, Lynchak O, Dziubenko N, Herheliuk T, Prylutskyy Y, Rybalchenko V, Ritter U. Water-soluble pristine C60 fullerene attenuates acetaminophen-induced liver injury. Bioimpacts 2019;9:227-37. [PMID: 31799159 DOI: 10.15171/bi.2019.28] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 4.5] [Reference Citation Analysis]
11 Belli V, Sforza V, Cardone C, Martinelli E, Barra G, Matrone N, Napolitano S, Morgillo F, Tuccillo C, Federico A, Dallio M, Loguercio C, Gravina AG, De Palma R, Ciardiello F, Troiani T. Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer. Oncotarget 2017;8:68305-16. [PMID: 28978118 DOI: 10.18632/oncotarget.20054] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 4.0] [Reference Citation Analysis]
12 Abenavoli L, Greco M, Milic N, Accattato F, Foti D, Gulletta E, Luzza F. Effect of Mediterranean Diet and Antioxidant Formulation in Non-Alcoholic Fatty Liver Disease: A Randomized Study. Nutrients 2017;9:E870. [PMID: 28805669 DOI: 10.3390/nu9080870] [Cited by in Crossref: 45] [Cited by in F6Publishing: 39] [Article Influence: 11.3] [Reference Citation Analysis]
13 Zhang R, Xu D, Zhang Y, Wang R, Yang N, Lou Y, Zhao H, Aa J, Wang G, Xie Y. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease. Drug Metab Dispos 2021;49:770-9. [PMID: 34183378 DOI: 10.1124/dmd.121.000438] [Reference Citation Analysis]
14 Sayed AM, Hassanein EH, Salem SH, Hussein OE, Mahmoud AM. Flavonoids-mediated SIRT1 signaling activation in hepatic disorders. Life Sciences 2020;259:118173. [DOI: 10.1016/j.lfs.2020.118173] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 7.0] [Reference Citation Analysis]
15 Sikander M, Malik S, Rodriguez A, Yallapu MM, Narula AS, Satapathy SK, Dhevan V, Chauhan SC, Jaggi M. Role of Nutraceuticals in COVID-19 Mediated Liver Dysfunction. Molecules 2020;25:E5905. [PMID: 33322162 DOI: 10.3390/molecules25245905] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
16 Liu B, Liu W, Liu P, Liu X, Song X, Hayashi T, Onodera S, Ikejima T. Silibinin Alleviates the Learning and Memory Defects in Overtrained Rats Accompanying Reduced Neuronal Apoptosis and Senescence. Neurochem Res 2019;44:1818-29. [PMID: 31102026 DOI: 10.1007/s11064-019-02816-2] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 4.5] [Reference Citation Analysis]
17 Saeed M, Babazadeh D, Arif M, Arain M, Bhutto Z, Shar A, Kakar M, Manzoor R, Chao S. Silymarin: a potent hepatoprotective agent in poultry industry. World's Poultry Science Journal 2017;73:483-92. [DOI: 10.1017/s0043933917000538] [Cited by in Crossref: 18] [Article Influence: 9.0] [Reference Citation Analysis]
18 Bijak M, Synowiec E, Sitarek P, Sliwiński T, Saluk-Bijak J. Evaluation of the Cytotoxicity and Genotoxicity of Flavonolignans in Different Cellular Models. Nutrients 2017;9:E1356. [PMID: 29240674 DOI: 10.3390/nu9121356] [Cited by in Crossref: 15] [Cited by in F6Publishing: 17] [Article Influence: 3.8] [Reference Citation Analysis]
19 Zhang T, Kawaguchi N, Tsuji K, Hayama E, Furutani Y, Sugiyama H, Nakanishi T. Silibinin Upregulates CXCR4 Expression in Cultured Bone Marrow Cells (BMCs) Especially in Pulmonary Arterial Hypertension Rat Model. Cells 2020;9:E1276. [PMID: 32455728 DOI: 10.3390/cells9051276] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
20 Soleimani V, Delghandi PS, Moallem SA, Karimi G. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytotherapy Research 2019;33:1627-38. [DOI: 10.1002/ptr.6361] [Cited by in Crossref: 43] [Cited by in F6Publishing: 30] [Article Influence: 21.5] [Reference Citation Analysis]
21 Sahin E, Bagci R, Bektur Aykanat NE, Kacar S, Sahinturk V. Silymarin attenuated nonalcoholic fatty liver disease through the regulation of endoplasmic reticulum stress proteins GRP78 and XBP-1 in mice. J Food Biochem 2020;44:e13194. [PMID: 32189355 DOI: 10.1111/jfbc.13194] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 6.0] [Reference Citation Analysis]
22 Marchegiani A, Fruganti A, Gavazza A, Mangiaterra S, Candellone A, Fusi E, Rossi G, Cerquetella M. Evidences on Molecules Most Frequently Included in Canine and Feline Complementary Feed to Support Liver Function. Vet Med Int 2020;2020:9185759. [PMID: 32454964 DOI: 10.1155/2020/9185759] [Reference Citation Analysis]
23 Méndez-Sánchez N, Dibildox-Martinez M, Sosa-Noguera J, Sánchez-Medal R, Flores-Murrieta FJ. Superior silybin bioavailability of silybin-phosphatidylcholine complex in oily-medium soft-gel capsules versus conventional silymarin tablets in healthy volunteers. BMC Pharmacol Toxicol 2019;20:5. [PMID: 30635055 DOI: 10.1186/s40360-018-0280-8] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 5.0] [Reference Citation Analysis]
24 Jouhari S, Mohammadzadeh A, Soltanghoraee H, Mohammadi Z, Khazali S, Mirzadegan E, Lakpour N, Fatemi F, Zafardoust S, Mohazzab A, Naderi MM. Effects of silymarin, cabergoline and letrozole on rat model of endometriosis. Taiwan J Obstet Gynecol 2018;57:830-5. [PMID: 30545536 DOI: 10.1016/j.tjog.2018.10.011] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 5.0] [Reference Citation Analysis]
25 Valentino G, Zivko C, Weber F, Brülisauer L, Luciani P. Synergy of Phospholipid-Drug Formulations Significantly Deactivates Profibrogenic Human Hepatic Stellate Cells. Pharmaceutics 2019;11:E676. [PMID: 31842373 DOI: 10.3390/pharmaceutics11120676] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
26 Wojas O, Krzych-Fałta E, Samel-Kowalik P, Żalikowska-Gardocka M, Majsiak E, Mari A, Samoliński B. A case of allergy to Silybum marianum (milk thistle) and Eragrostis tef (teff). Allergy Asthma Clin Immunol 2020;16:23. [PMID: 32322285 DOI: 10.1186/s13223-020-00421-5] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
27 Sharifpanah F, Ali EH, Wartenberg M, Sauer H. The milk thistle ( Silybum marianum ) compound Silibinin stimulates leukopoiesis from mouse embryonic stem cells. Phytotherapy Research 2018. [DOI: 10.1002/ptr.6241] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
28 Cicero AFG, Colletti A, Bellentani S. Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical Evidence. Nutrients 2018;10:E1153. [PMID: 30142943 DOI: 10.3390/nu10091153] [Cited by in Crossref: 48] [Cited by in F6Publishing: 39] [Article Influence: 16.0] [Reference Citation Analysis]
29 Liu CH, Jassey A, Hsu HY, Lin LT. Antiviral Activities of Silymarin and Derivatives.Molecules. 2019;24. [PMID: 31010179 DOI: 10.3390/molecules24081552] [Cited by in Crossref: 24] [Cited by in F6Publishing: 21] [Article Influence: 12.0] [Reference Citation Analysis]
30 Drouet S, Abbasi B, Falguières A, Ahmad W, Sumaira, Ferroud C, Doussot J, Vanier J, Lainé E, Hano C. Single Laboratory Validation of a Quantitative Core Shell-Based LC Separation for the Evaluation of Silymarin Variability and Associated Antioxidant Activity of Pakistani Ecotypes of Milk Thistle (Silybum Marianum L.). Molecules 2018;23:904. [DOI: 10.3390/molecules23040904] [Cited by in Crossref: 20] [Cited by in F6Publishing: 5] [Article Influence: 6.7] [Reference Citation Analysis]
31 Aghashahi M, Momeni HR, Darbandi N. Impact of aluminium toxicity on vital human sperm parameters-Protective effects of silymarin. Andrologia 2020;52:e13742. [PMID: 33616990 DOI: 10.1111/and.13742] [Reference Citation Analysis]
32 Xie Y, Zhang D, Zhang J, Yuan J. Metabolism, Transport and Drug-Drug Interactions of Silymarin. Molecules 2019;24:E3693. [PMID: 31615114 DOI: 10.3390/molecules24203693] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 7.0] [Reference Citation Analysis]
33 Ebrahimpour-Koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-Jafarabadi M. Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial. Phytomedicine 2018;44:39-44. [PMID: 29895491 DOI: 10.1016/j.phymed.2018.03.050] [Cited by in Crossref: 20] [Cited by in F6Publishing: 15] [Article Influence: 6.7] [Reference Citation Analysis]
34 Sun R, Xu D, Wei Q, Zhang B, Aa J, Wang G, Xie Y. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother 2020;123:109721. [PMID: 31865143 DOI: 10.1016/j.biopha.2019.109721] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 4.5] [Reference Citation Analysis]
35 Bi X, Yuan Z, Qu B, Zhou H, Liu Z, Xie Y. Piperine enhances the bioavailability of silybin via inhibition of efflux transporters BCRP and MRP2. Phytomedicine 2019;54:98-108. [PMID: 30668388 DOI: 10.1016/j.phymed.2018.09.217] [Cited by in Crossref: 19] [Cited by in F6Publishing: 16] [Article Influence: 6.3] [Reference Citation Analysis]
36 Fenclova M, Stranska-Zachariasova M, Benes F, Novakova A, Jonatova P, Kren V, Vitek L, Hajslova J. Liquid chromatography-drift tube ion mobility-mass spectrometry as a new challenging tool for the separation and characterization of silymarin flavonolignans. Anal Bioanal Chem 2020;412:819-32. [PMID: 31919606 DOI: 10.1007/s00216-019-02274-3] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 8.0] [Reference Citation Analysis]
37 El-Latif El-Ghazaly MA, Rashed ER, Shafey GM, Zaki HF, Attia AS. Amelioration of thioacetamide-induced hepatic encephalopathy in rats by low-dose gamma irradiation. Environ Sci Pollut Res Int 2020;27:334-43. [PMID: 31786756 DOI: 10.1007/s11356-019-06934-w] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 3.5] [Reference Citation Analysis]
38 Abbas NAT, Awad MM, Nafea OE. Silymarin in combination with chlorogenic acid protects against hepatotoxicity induced by doxorubicin in rats: possible role of adenosine monophosphate-activated protein kinase pathway. Toxicol Res (Camb) 2020;9:771-7. [PMID: 33447361 DOI: 10.1093/toxres/tfaa080] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
39 Poór M, Boda G, Mohos V, Kuzma M, Bálint M, Hetényi C, Bencsik T. Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin. Biomedicine & Pharmacotherapy 2018;102:912-21. [DOI: 10.1016/j.biopha.2018.03.146] [Cited by in Crossref: 16] [Cited by in F6Publishing: 14] [Article Influence: 5.3] [Reference Citation Analysis]
40 Lee MK. Liposomes for Enhanced Bioavailability of Water-Insoluble Drugs: In Vivo Evidence and Recent Approaches. Pharmaceutics 2020;12:E264. [PMID: 32183185 DOI: 10.3390/pharmaceutics12030264] [Cited by in Crossref: 35] [Cited by in F6Publishing: 24] [Article Influence: 35.0] [Reference Citation Analysis]
41 Kim HG, Kim YH, Lee SB, Lee JS, Chae SW, Kim DG, Son CG. An Herbal Formula CGplus Ameliorates Stress-Induced Hepatic Injury in a BALB/c Mouse Model. Front Pharmacol 2020;11:447. [PMID: 32346367 DOI: 10.3389/fphar.2020.00447] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
42 Gugliandolo E, Crupi R, Biondi V, Licata P, Cuzzocrea S, Passantino A. Protective Effect of Silibinin on Lipopolysaccharide-Induced Inflammatory Responses in Equine Peripheral Blood Mononuclear Cells, an In Vitro Study. Animals (Basel) 2020;10:E2022. [PMID: 33153060 DOI: 10.3390/ani10112022] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
43 Chao CT, Yeh HY, Tsai YT, Chuang PH, Yuan TH, Huang JW, Chen HW. Natural and non-natural antioxidative compounds: potential candidates for treatment of vascular calcification. Cell Death Discov 2019;5:145. [PMID: 31754473 DOI: 10.1038/s41420-019-0225-z] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 9.5] [Reference Citation Analysis]
44 Kumar N, Jose J. Current developments in the nanomediated delivery of photoprotective phytochemicals. Environ Sci Pollut Res Int 2020;27:38446-71. [PMID: 32761528 DOI: 10.1007/s11356-020-10100-y] [Reference Citation Analysis]
45 Kronborg TM, Ytting H, Hobolth L, Møller S, Kimer N. Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study. Front Med (Lausanne) 2021;8:718896. [PMID: 34631742 DOI: 10.3389/fmed.2021.718896] [Reference Citation Analysis]
46 Chao WW, Chen SJ, Peng HC, Liao JW, Chou ST. Antioxidant Activity of Graptopetalum paraguayense E. Walther Leaf Extract Counteracts Oxidative Stress Induced by Ethanol and Carbon Tetrachloride Co-Induced Hepatotoxicity in Rats. Antioxidants (Basel) 2019;8:E251. [PMID: 31357705 DOI: 10.3390/antiox8080251] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
47 Al Kury LT, Dayyan F, Ali Shah F, Malik Z, Khalil AAK, Alattar A, Alshaman R, Ali A, Khan Z. Ginkgo biloba Extract Protects against Methotrexate-Induced Hepatotoxicity: A Computational and Pharmacological Approach. Molecules 2020;25:E2540. [PMID: 32486047 DOI: 10.3390/molecules25112540] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 7.0] [Reference Citation Analysis]
48 Anushiravani A, Haddadi N, Pourfarmanbar M, Mohammadkarimi V. Treatment options for nonalcoholic fatty liver disease: a double-blinded randomized placebo-controlled trial.Eur J Gastroenterol Hepatol. 2019;31:613-617. [PMID: 30920975 DOI: 10.1097/MEG.0000000000001369] [Cited by in Crossref: 22] [Cited by in F6Publishing: 12] [Article Influence: 11.0] [Reference Citation Analysis]
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50 Park S, Cho SM, Jin BR, Yang HJ, Yi QJ. Mixture of blackberry leaf and fruit extracts alleviates non-alcoholic steatosis, enhances intestinal integrity, and increases Lactobacillus and Akkermansia in rats. Exp Biol Med (Maywood) 2019;244:1629-41. [PMID: 31752528 DOI: 10.1177/1535370219889319] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
51 Oprea E, Ruta LL, Farcasanu IC. Pharmacological Aspects and Health Impact of Sports and Energy Drinks. Sports and Energy Drinks. Elsevier; 2019. pp. 65-129. [DOI: 10.1016/b978-0-12-815851-7.00003-6] [Cited by in Crossref: 2] [Article Influence: 1.0] [Reference Citation Analysis]
52 Cuyàs E, Verdura S, Micol V, Joven J, Bosch-barrera J, Encinar JA, Menendez JA. Revisiting silibinin as a novobiocin-like Hsp90 C-terminal inhibitor: Computational modeling and experimental validation. Food and Chemical Toxicology 2019;132:110645. [DOI: 10.1016/j.fct.2019.110645] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 3.5] [Reference Citation Analysis]
53 Feng R, Chen JH, Liu CH, Xia FB, Xiao Z, Zhang X, Wan JB. A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease in mice. Phytomedicine 2019;58:152824. [PMID: 30836218 DOI: 10.1016/j.phymed.2019.152824] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 6.0] [Reference Citation Analysis]
54 Vrba J, Papoušková B, Kosina P, Lněničková K, Valentová K, Ulrichová J. Identification of Human Sulfotransferases Active towards Silymarin Flavonolignans and Taxifolin. Metabolites 2020;10:E329. [PMID: 32806559 DOI: 10.3390/metabo10080329] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
55 Shen Y, Zhao H, Wang Z, Guan W, Kang X, Tai X, Sun Y. Silibinin declines blue light-induced apoptosis and inflammation through MEK/ERK/CREB of retinal ganglion cells. Artif Cells Nanomed Biotechnol 2019;47:4059-65. [PMID: 31631701 DOI: 10.1080/21691401.2019.1671430] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 7.0] [Reference Citation Analysis]
56 Kato E, Kushibiki N, Satoh H, Kawabata J. Silychristin derivatives conjugated with coniferylalcohols from silymarin and their pancreatic α-amylase inhibitory activity. Natural Product Research 2020;34:759-65. [DOI: 10.1080/14786419.2018.1499639] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
57 Yue H, Wang P, Zhang L, Ning D, Cai W, Wang Y, Wang J. Sialoglycoproteins isolated from the eggs of Carassius auratus alleviates CCL4-induced liver injury via downregulation of the IRE-α/NF-κB signaling pathway. J Food Biochem 2021;:e13964. [PMID: 34730246 DOI: 10.1111/jfbc.13964] [Reference Citation Analysis]
58 Camini FC, da Silva TF, da Silva Caetano CC, Almeida LT, Ferraz AC, Alves Vitoreti VM, de Mello Silva B, de Queiroz Silva S, de Magalhães JC, de Brito Magalhães CL. Antiviral activity of silymarin against Mayaro virus and protective effect in virus-induced oxidative stress. Antiviral Res 2018;158:8-12. [PMID: 30076863 DOI: 10.1016/j.antiviral.2018.07.023] [Cited by in Crossref: 30] [Cited by in F6Publishing: 27] [Article Influence: 10.0] [Reference Citation Analysis]
59 Liang CW, Yang HC, Islam MM, Nguyen PAA, Feng YT, Hou ZY, Huang CW, Poly TN, Li YJ. Predicting Hepatocellular Carcinoma With Minimal Features From Electronic Health Records: Development of a Deep Learning Model. JMIR Cancer 2021;7:e19812. [PMID: 34709180 DOI: 10.2196/19812] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
60 Piotrowska-Kempisty H, Nowicki M, Jodynis-Liebert J, Kurpik M, Ewertowska M, Adamska T, Oszmiański J, Kujawska M. Assessment of Hepatoprotective Effect of Chokeberry Juice in Rats Treated Chronically with Carbon Tetrachloride. Molecules 2020;25:E1268. [PMID: 32168847 DOI: 10.3390/molecules25061268] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 5.0] [Reference Citation Analysis]
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