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For: Long HZ, Cheng Y, Zhou ZW, Luo HY, Wen DD, Gao LC. PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer's Disease and Parkinson's Disease. Front Pharmacol 2021;12:648636. [PMID: 33935751 DOI: 10.3389/fphar.2021.648636] [Cited by in Crossref: 41] [Cited by in F6Publishing: 48] [Article Influence: 41.0] [Reference Citation Analysis]
Number Citing Articles
1 Shen J, Hang L, He F, Xu X, Sun H. Clinical Effect of Application of Interventional Treatment Models for Improvement of Quality of Postoperative Recovery in Elderly Patients with Total Hip Arthroplasty. IJGM 2022;Volume 15:8343-8351. [DOI: 10.2147/ijgm.s388209] [Reference Citation Analysis]
2 Goyal A, Agrawal A, Verma A, Dubey N. The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease. Experimental and Molecular Pathology 2022. [DOI: 10.1016/j.yexmp.2022.104846] [Reference Citation Analysis]
3 Ojha U, Khanal S, Park P, Hong JT, Choi D. Intermittent fasting protects the nigral dopaminergic neurons from MPTP-mediated dopaminergic neuronal injury in mice. The Journal of Nutritional Biochemistry 2022. [DOI: 10.1016/j.jnutbio.2022.109212] [Reference Citation Analysis]
4 Kirchenwitz M, Stahnke S, Grunau K, Melcher L, van Ham M, Rottner K, Steffen A, Stradal TEB. The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection. Sci Rep 2022;12:17805. [PMID: 36284196 DOI: 10.1038/s41598-022-20563-3] [Reference Citation Analysis]
5 Wang Q, Shen Z, Zhang S, Sun Y, Zheng F, Li Y. Protective effects and mechanism of puerarin targeting PI3K/Akt signal pathway on neurological diseases. Front Pharmacol 2022;13. [DOI: 10.3389/fphar.2022.1022053] [Reference Citation Analysis]
6 Lin T, Chang K, Chiu Y, Weng Z, Sun Y, Lin W, Lee-chen G, Chen C. Neuroprotective Action of Coumarin Derivatives through Activation of TRKB-CREB-BDNF Pathway and Reduction of Caspase Activity in Neuronal Cells Expressing Pro-Aggregated Tau Protein. IJMS 2022;23:12734. [DOI: 10.3390/ijms232112734] [Reference Citation Analysis]
7 Kaviyarasan S, Chung Sia EL, Retinasamy T, Arulsamy A, Shaikh MF. Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases: A molecular crosstalk. Front Aging Neurosci 2022;14:1015837. [DOI: 10.3389/fnagi.2022.1015837] [Reference Citation Analysis]
8 Kishk SM, Eltamany EE, Nafie MS, Khinkar RM, Hareeri RH, Elhady SS, Yassen ASA. Design and Synthesis of Coumarin Derivatives as Cytotoxic Agents through PI3K/AKT Signaling Pathway Inhibition in HL60 and HepG2 Cancer Cells. Molecules 2022;27:6709. [PMID: 36235247 DOI: 10.3390/molecules27196709] [Reference Citation Analysis]
9 Dafnis I, Mountaki C, Fanarioti E, Mastellos DC, Karvelas M, Karathanos VT, Tzinia A, Dermon CR, Chroni A. Temporal Pattern of Neuroinflammation Associated with a Low Glycemic Index Diet in the 5xFAD Mouse Model of Alzheimer's Disease. Mol Neurobiol 2022. [PMID: 36175825 DOI: 10.1007/s12035-022-03047-3] [Reference Citation Analysis]
10 Gao CX, Tang CH, Wu TJ, Hu Y, Peng YL, Liu ML, Liu QW, Chen HF, Yang ZH, Zheng X. Anticancer activity of oleanolic acid and its derivatives modified at A-ring and C-28 position. J Asian Nat Prod Res 2022;:1-14. [PMID: 36151896 DOI: 10.1080/10286020.2022.2120863] [Reference Citation Analysis]
11 Wang X, Xiu C, Yang J, Liu Y, Zhang J, Lei Y. Whole-Transcriptome Sequencing Analysis Reveal Mechanisms of Yiqi Huoxue Yangyin (YHY) Decoction in Ameliorating D-gal-induced Cardiac Aging.. [DOI: 10.21203/rs.3.rs-2056422/v1] [Reference Citation Analysis]
12 Khezri MR, Esmaeili A, Ghasemnejad-berenji M. Platelet Activation and Alzheimer’s Disease: The Probable Role of PI3K/AKT Pathway. JAD 2022. [DOI: 10.3233/jad-220663] [Reference Citation Analysis]
13 Li HL, Zhang SY, Ren YS, Zhou JC, Zhou YX, Huang WZ, Piao XH, Yang ZY, Wang SM, Ge YW. Identification of ellagic acid and urolithins as natural inhibitors of Aβ25-35-induced neurotoxicity and the mechanism predication using network pharmacology analysis and molecular docking. Front Nutr 2022;9:966276. [PMID: 35983489 DOI: 10.3389/fnut.2022.966276] [Reference Citation Analysis]
14 Poddar NK, Agarwal D, Agrawal Y, Wijayasinghe YS, Mukherjee A, Khan S. Deciphering the enigmatic crosstalk between prostate cancer and Alzheimer's disease: A current update on molecular mechanisms and combination therapy. Biochim Biophys Acta Mol Basis Dis 2022;1868:166524. [PMID: 35985445 DOI: 10.1016/j.bbadis.2022.166524] [Reference Citation Analysis]
15 Guo L, Qu B, Song C, Zhu S, Gong N, Sun J. Celastrol attenuates 6-hydroxydopamine-induced neurotoxicity by regulating the miR-146a/PI3K/Akt/mTOR signaling pathways in differentiated rat pheochromocytoma cells. J Affect Disord 2022;316:233-42. [PMID: 35981627 DOI: 10.1016/j.jad.2022.08.026] [Reference Citation Analysis]
16 Wang Y, Wu X, Yang K, Liu Q, Jiang B, Yang R, Xiao P, He C. Integrating network pharmacology analysis and pharmacodynamic evaluation for exploring the active components and molecular mechanism of moutan seed coat extract to improve cognitive impairment. Front Pharmacol 2022;13:952876. [DOI: 10.3389/fphar.2022.952876] [Reference Citation Analysis]
17 Md Razip NN, Mohd Noor S, Norazit A, Nordin N, Sakeh NM, Khaza’ai H. An Association between Insulin Resistance and Neurodegeneration in Zebrafish Larval Model (Danio rerio). IJMS 2022;23:8290. [DOI: 10.3390/ijms23158290] [Reference Citation Analysis]
18 Sanchez-Mirasierra I, Ghimire S, Hernandez-Diaz S, Soukup SF. Targeting Macroautophagy as a Therapeutic Opportunity to Treat Parkinson's Disease. Front Cell Dev Biol 2022;10:921314. [PMID: 35874822 DOI: 10.3389/fcell.2022.921314] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
19 Dai Y, Jia P, Zhao Z, Gottlieb A. A Method for Bridging Population-Specific Genotypes to Detect Gene Modules Associated with Alzheimer's Disease. Cells 2022;11:2219. [PMID: 35883662 DOI: 10.3390/cells11142219] [Reference Citation Analysis]
20 Yao Z, Li J, Bian L, Li Q, Wang X, Yang X, Wei X, Wan G, Wang Y, Shi J, Guo J. Nootkatone alleviates rotenone-induced Parkinson's disease symptoms through activation of the PI3K/Akt signaling pathway. Phytother Res 2022. [PMID: 35833337 DOI: 10.1002/ptr.7552] [Reference Citation Analysis]
21 La Rosa F, Zoia CP, Bazzini C, Bolognini A, Saresella M, Conti E, Ferrarese C, Piancone F, Marventano I, Galimberti D, Fenoglio C, Scarpini E, Clerici M. Modulation of MAPK- and PI3/AKT-Dependent Autophagy Signaling by Stavudine (D4T) in PBMC of Alzheimer’s Disease Patients. Cells 2022;11:2180. [DOI: 10.3390/cells11142180] [Reference Citation Analysis]
22 Kim YJ. Activity-induced synaptic structural modifications by Akt. Biochem Biophys Res Commun 2022;621:94-100. [PMID: 35820284 DOI: 10.1016/j.bbrc.2022.06.093] [Reference Citation Analysis]
23 Saleh DO, Mahmoud SS, Hassan A, Sanad EF. Doxorubicin-induced hepatic toxicity in rats: Mechanistic protective role of Omega-3 fatty acids through Nrf2/HO-1 activation and PI3K/Akt/GSK-3β axis modulation. Saudi Journal of Biological Sciences 2022;29:103308. [DOI: 10.1016/j.sjbs.2022.103308] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
24 Li Q, Rubin L, Silva M, Li S, Yang C, Lazarovici P, Zheng W. Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease. Oxid Med Cell Longev 2022;2022:3777021. [PMID: 35746960 DOI: 10.1155/2022/3777021] [Reference Citation Analysis]
25 Kang J, Wang Y, Guo X, He X, Liu W, Chen H, Wang Z, Lin A, Kang X. N-acetylserotonin protects PC12 cells from hydrogen peroxide induced damage through ROS mediated PI3K / AKT pathway. Cell Cycle 2022;:1-15. [PMID: 35758219 DOI: 10.1080/15384101.2022.2092817] [Reference Citation Analysis]
26 Huang J, Xu Z, Chen H, Lin Y, Wei J, Wang S, Yu H, Huang S, Zhang Y, Li C, Zhou X. Shen Qi Wan Ameliorates Learning and Memory Impairment Induced by STZ in AD Rats through PI3K/AKT Pathway. Brain Sci 2022;12:758. [PMID: 35741643 DOI: 10.3390/brainsci12060758] [Reference Citation Analysis]
27 Faenza I, Blalock WL. Innate Immunity: A Balance between Disease and Adaption to Stress. Biomolecules 2022;12:737. [PMID: 35625664 DOI: 10.3390/biom12050737] [Reference Citation Analysis]
28 Moayedi K, Orandi S, Ebrahimi R, Tanhapour M, Moradi M, Abbastabar M, Golestani A. A novel approach to type 3 diabetes mechanism: The interplay between noncoding RNAs and insulin signaling pathway in Alzheimer's disease. J Cell Physiol 2022. [PMID: 35580144 DOI: 10.1002/jcp.30779] [Reference Citation Analysis]
29 Lang XY, Hu Y, Bai JP, Wang J, Qin XY, Lan R. Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation. Front Pharmacol 2022;13:903235. [PMID: 35571135 DOI: 10.3389/fphar.2022.903235] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
30 Huuki-myers LA, Montgomery KD, Kwon SH, Page SC, Hicks SC, Maynard KR, Collado-torres L. Data-driven Identification of Total RNA Expression Genes (TREGs) for Estimation of RNA Abundance in Heterogeneous Cell Types.. [DOI: 10.1101/2022.04.28.489923] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
31 Sarić N, Hashimoto-Torii K, Jevtović-Todorović V, Ishibashi N. Nonapoptotic caspases in neural development and in anesthesia-induced neurotoxicity. Trends Neurosci 2022:S0166-2236(22)00058-3. [PMID: 35491256 DOI: 10.1016/j.tins.2022.03.007] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
32 Han R, Yu Y, Zhao K, Wei J, Hui Y, Gao JM. Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 cells. Phytomedicine 2022;101:154124. [PMID: 35487038 DOI: 10.1016/j.phymed.2022.154124] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
33 Moreira NCDS, Lima JEBDF, Fiori Marchiori M, Carvalho I, Sakamoto-hojo ET. Neuroprotective Effects of Cholinesterase Inhibitors: Current Scenario in Therapies for Alzheimer’s Disease and Future Perspectives. ADR 2022. [DOI: 10.3233/adr-210061] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
34 da Rosa-junior NT, Parmeggiani B, Glänzel NM, de Moura Alvorcem L, Brondani M, Britto R, Grings M, Ortiz VD, Turck P, da Rosa Araujo AS, Wajner M, Leipnitz G. Antioxidant system disturbances and mitochondrial dysfunction induced by 3-methyglutaric acid in rat heart are prevented by bezafibrate. European Journal of Pharmacology 2022. [DOI: 10.1016/j.ejphar.2022.174950] [Reference Citation Analysis]
35 Park YJ, Lim JY, Kwon S, Shin M. Aucubin suppresses lipopolysaccharide-induced pro-inflammatory responses by blocking the NF-κB translocation signaling pathways in activated microglial cells. Phytochemistry Letters 2022;48:120-7. [DOI: 10.1016/j.phytol.2022.02.006] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
36 Varela L, Garcia-Rendueles MER. Oncogenic Pathways in Neurodegenerative Diseases. Int J Mol Sci 2022;23:3223. [PMID: 35328644 DOI: 10.3390/ijms23063223] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
37 Ren X, Zhang J, Zhao Y, Sun L. Senegenin Inhibits Aβ1-42-Induced PC12 Cells Apoptosis and Oxidative Stress via Activation of the PI3K/Akt Signaling Pathway. NDT 2022;Volume 18:513-24. [DOI: 10.2147/ndt.s346238] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 5.0] [Reference Citation Analysis]
38 Tan MA, Sharma N, An SSA. Phyto-Carbazole Alkaloids from the Rutaceae Family as Potential Protective Agents against Neurodegenerative Diseases. Antioxidants 2022;11:493. [DOI: 10.3390/antiox11030493] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 4.0] [Reference Citation Analysis]
39 Pushparaj PN, Kalamegam G, Wali Sait KH, Rasool M. Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia. Front Pharmacol 2022;12:720170. [DOI: 10.3389/fphar.2021.720170] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
40 Nelke A, García-lópez S, Martínez-serrano A, Pereira MP. Multifactoriality of Parkinson’s Disease as Explored Through Human Neural Stem Cells and Their Transplantation in Middle-Aged Parkinsonian Mice. Front Pharmacol 2022;12:773925. [DOI: 10.3389/fphar.2021.773925] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
41 Chen P, Chen F, Lei J, Wang G, Zhou B. The Gut Microbiota Metabolite Urolithin B Improves Cognitive Deficits by Inhibiting Cyt C-Mediated Apoptosis and Promoting the Survival of Neurons Through the PI3K Pathway in Aging Mice. Front Pharmacol 2021;12:768097. [PMID: 34867396 DOI: 10.3389/fphar.2021.768097] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
42 Varlamova EG, Turovsky EA, Babenko VA, Plotnikov EY. The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca2+ Signaling System of Astrocytes and Reactive Astrogliosis. Int J Mol Sci 2021;22:12825. [PMID: 34884629 DOI: 10.3390/ijms222312825] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 5.0] [Reference Citation Analysis]
43 Xie Y, Yan B, Hou M, Zhou M, Liu C, Sun M, He K, Fang C, Chen Y, Huang L. Erzhi pills ameliorate cognitive dysfunction and alter proteomic hippocampus profiles induced by d-galactose and Aβ1-40 injection in ovariectomized Alzheimer's disease model rats. Pharm Biol 2021;59:1402-14. [PMID: 34672897 DOI: 10.1080/13880209.2021.1990353] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
44 Nebrisi EE. Neuroprotective Activities of Curcumin in Parkinson's Disease: A Review of the Literature. Int J Mol Sci 2021;22:11248. [PMID: 34681908 DOI: 10.3390/ijms222011248] [Cited by in Crossref: 12] [Cited by in F6Publishing: 14] [Article Influence: 12.0] [Reference Citation Analysis]
45 Zhou Y, Wang C, Kou J, Wang M, Rong X, Pu X, Xie X, Han G, Pang X. Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis. Pharm Biol 2021;59:1378-87. [PMID: 34629029 DOI: 10.1080/13880209.2021.1986077] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
46 Regenthal R, Rong P, Krügel U. Nutraceuticals in mental diseases - Bridging the gap between traditional use and modern pharmacology. Curr Opin Pharmacol 2021;61:62-8. [PMID: 34628304 DOI: 10.1016/j.coph.2021.08.017] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]