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For: Murga C, Arcones AC, Cruces-Sande M, Briones AM, Salaices M, Mayor F Jr. G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases. Front Pharmacol 2019;10:112. [PMID: 30837878 DOI: 10.3389/fphar.2019.00112] [Cited by in Crossref: 30] [Cited by in F6Publishing: 29] [Article Influence: 10.0] [Reference Citation Analysis]
Number Citing Articles
1 Takenaka Y, Tanaka R, Kitabatake K, Kuramochi K, Aoki S, Tsukimoto M. Profiling Differential Effects of 5 Selective Serotonin Reuptake Inhibitors on TLRs-Dependent and -Independent IL-6 Production in Immune Cells Identifies Fluoxetine as Preferred Anti-Inflammatory Drug Candidate. Front Pharmacol 2022;13:874375. [DOI: 10.3389/fphar.2022.874375] [Reference Citation Analysis]
2 Arcones AC, Vila-Bedmar R, Mirasierra M, Cruces-Sande M, Vallejo M, Jones B, Tomas A, Mayor F Jr, Murga C. GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo. BMC Biol 2021;19:40. [PMID: 33658023 DOI: 10.1186/s12915-021-00966-w] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
3 Abd Alla J, Quitterer U. The RAF Kinase Inhibitor Protein (RKIP): Good as Tumour Suppressor, Bad for the Heart. Cells 2022;11:654. [PMID: 35203304 DOI: 10.3390/cells11040654] [Reference Citation Analysis]
4 Cruces-Sande M, Arcones AC, Vila-Bedmar R, Val-Blasco A, Sharabi K, Díaz-Rodríguez D, Puigserver P, Mayor F Jr, Murga C. Autophagy mediates hepatic GRK2 degradation to facilitate glucagon-induced metabolic adaptation to fasting. FASEB J 2020;34:399-409. [PMID: 31914606 DOI: 10.1096/fj.201901444R] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.7] [Reference Citation Analysis]
5 Reichel M, Weitzel V, Klement L, Hoffmann C, Drube J. Suitability of GRK Antibodies for Individual Detection and Quantification of GRK Isoforms in Western Blots. Int J Mol Sci 2022;23:1195. [PMID: 35163118 DOI: 10.3390/ijms23031195] [Reference Citation Analysis]
6 Penela P, Inserte J, Ramos P, Rodriguez-Sinovas A, Garcia-Dorado D, Mayor F Jr. Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion. EBioMedicine 2019;48:605-18. [PMID: 31594751 DOI: 10.1016/j.ebiom.2019.09.019] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 4.3] [Reference Citation Analysis]
7 Palano G, Jansson M, Backmark A, Martinsson S, Sabirsh A, Hultenby K, Åkerblad P, Granberg KL, Jennbacken K, Müllers E, Hansson EM. A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity. J Mol Cell Cardiol 2020;142:105-17. [PMID: 32277974 DOI: 10.1016/j.yjmcc.2020.04.002] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
8 Li N, Shan S, Li XQ, Chen TT, Qi M, Zhang SN, Wang ZY, Zhang LL, Wei W, Sun WY. G Protein-Coupled Receptor Kinase 2 as Novel Therapeutic Target in Fibrotic Diseases. Front Immunol 2021;12:822345. [PMID: 35111168 DOI: 10.3389/fimmu.2021.822345] [Reference Citation Analysis]
9 Hounkpe BW, Benatti RO, Carvalho BS, De Paula EV. Identification of common and divergent gene expression signatures in patients with venous and arterial thrombosis using data from public repositories. PLoS One 2020;15:e0235501. [PMID: 32780732 DOI: 10.1371/journal.pone.0235501] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
10 Maning J, McCrink KA, Pollard CM, Desimine VL, Ghandour J, Perez A, Cora N, Ferraino KE, Parker BM, Brill AR, Aukszi B, Lymperopoulos A. Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition. Int J Mol Sci 2020;21:E2868. [PMID: 32326036 DOI: 10.3390/ijms21082868] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 3.5] [Reference Citation Analysis]
11 Perdices-lopez C, Avendaño MS, Barroso A, Gaytán F, Ruiz-pino F, Vázquez MJ, Leon S, Song YB, Sobrino V, Heras V, Romero-ruiz A, Roa J, Mayor F, Murga C, Pinilla L, Kaiser UB, Tena-sempere M. Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons. Metabolism 2022. [DOI: 10.1016/j.metabol.2022.155141] [Reference Citation Analysis]
12 Zou D, Wang H, Liu X, Xu ZP, Roberts MS, Zhao CX. Artificial cells for the treatment of liver diseases. Acta Biomater 2021;130:98-114. [PMID: 34126265 DOI: 10.1016/j.actbio.2021.06.012] [Reference Citation Analysis]
13 Reglero C, Ortiz Del Castillo B, Rivas V, Mayor F Jr, Penela P. Mdm2-Mediated Downmodulation of GRK2 Restricts Centrosome Separation for Proper Chromosome Congression. Cells 2021;10:729. [PMID: 33806062 DOI: 10.3390/cells10040729] [Reference Citation Analysis]
14 Lee SP, Qi J, Xu G, Rankin MM, Littrell J, Xu JZ, Bakaj I, Pocai A. GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action. Front Endocrinol (Lausanne) 2021;12:652628. [PMID: 34054727 DOI: 10.3389/fendo.2021.652628] [Reference Citation Analysis]
15 Knox M, Vinet R, Fuentes L, Morales B, Martínez JL. A Review of Endothelium-Dependent and -Independent Vasodilation Induced by Phytochemicals in Isolated Rat Aorta. Animals (Basel) 2019;9:E623. [PMID: 31470540 DOI: 10.3390/ani9090623] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
16 Verma K, Pant M, Paliwal S, Dwivedi J, Sharma S. An Insight on Multicentric Signaling of Angiotensin II in Cardiovascular system: A Recent Update. Front Pharmacol 2021;12:734917. [PMID: 34489714 DOI: 10.3389/fphar.2021.734917] [Reference Citation Analysis]
17 Echeverría E, Velez Rueda AJ, Cabrera M, Juritz E, Burghi V, Fabián L, Davio C, Lorenzano Menna P, Fernández NC. Identification of inhibitors of the RGS homology domain of GRK2 by docking-based virtual screening. Life Sciences 2019;239:116872. [DOI: 10.1016/j.lfs.2019.116872] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
18 Rosales TO, Horewicz VV, Ferreira MA, Nardi GM, Assreuy J. Dynamics of GRK2 in the kidney: a putative mechanism for sepsis-associated kidney injury. Clin Sci (Lond) 2021;135:2341-56. [PMID: 34622918 DOI: 10.1042/CS20210462] [Reference Citation Analysis]
19 Carlson EL, Karuppagounder V, Pinamont WJ, Yoshioka NK, Ahmad A, Schott EM, Le Bleu HK, Zuscik MJ, Elbarbary RA, Kamal F. Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis. Sci Transl Med 2021;13:eaau8491. [PMID: 33568523 DOI: 10.1126/scitranslmed.aau8491] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
20 Alonazi ASA, Willets JM. G protein-coupled receptor kinase 2 is essential to enable vasoconstrictor-mediated arterial smooth muscle proliferation. Cell Signal 2021;88:110152. [PMID: 34555505 DOI: 10.1016/j.cellsig.2021.110152] [Reference Citation Analysis]
21 Arcones AC, Cruces-Sande M, Ramos P, Mayor F Jr, Murga C. Sex Differences in High Fat Diet-Induced Metabolic Alterations Correlate with Changes in the Modulation of GRK2 Levels. Cells 2019;8:E1464. [PMID: 31752326 DOI: 10.3390/cells8111464] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
22 Zhai R, Snyder J, Montgomery S, Sato PY. Double life: How GRK2 and β-arrestin signaling participate in diseases. Cellular Signalling 2022. [DOI: 10.1016/j.cellsig.2022.110333] [Reference Citation Analysis]
23 Bencivenga L, Palaia ME, Sepe I, Gambino G, Komici K, Cannavo A, Femminella GD, Rengo G. Why Do We Not Assess Sympathetic Nervous System Activity in Heart Failure Management: Might GRK2 Serve as a New Biomarker? Cells 2021;10:457. [PMID: 33669936 DOI: 10.3390/cells10020457] [Reference Citation Analysis]
24 Xu G, Gaul MD, Liu Z, DesJarlais RL, Qi J, Wang W, Krosky D, Petrounia I, Milligan CM, Hermans A, Lu HR, Huang DZ, Xu JZ, Spurlino JC. Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor. Bioorg Med Chem Lett 2020;30:127602. [PMID: 33038544 DOI: 10.1016/j.bmcl.2020.127602] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
25 Kowalska M, Nowaczyk J, Fijałkowski Ł, Nowaczyk A. Paroxetine-Overview of the Molecular Mechanisms of Action. Int J Mol Sci 2021;22:1662. [PMID: 33562229 DOI: 10.3390/ijms22041662] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
26 Laudette M, Formoso K, Lezoualc'h F. GRKs and Epac1 Interaction in Cardiac Remodeling and Heart Failure. Cells 2021;10:154. [PMID: 33466800 DOI: 10.3390/cells10010154] [Reference Citation Analysis]
27 Kang JH, Toita R, Kawano T, Murata M, Asai D. Design of substrates and inhibitors of G protein-coupled receptor kinase 2 (GRK2) based on its phosphorylation reaction. Amino Acids 2020;52:863-70. [PMID: 32577910 DOI: 10.1007/s00726-020-02864-x] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
28 Arcones AC, Martínez-Cignoni MR, Vila-Bedmar R, Yáñez C, Lladó I, Proenza AM, Mayor F Jr, Murga C. Cardiac GRK2 Protein Levels Show Sexual Dimorphism during Aging and Are Regulated by Ovarian Hormones. Cells 2021;10:673. [PMID: 33803070 DOI: 10.3390/cells10030673] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
29 Kraboth Z, Kajtár B, Gálik B, Gyenesei A, Miseta A, Kalman B. Involvement of the Catecholamine Pathway in Glioblastoma Development. Cells 2021;10:549. [PMID: 33806345 DOI: 10.3390/cells10030549] [Reference Citation Analysis]
30 Cheng H, Guo P, Su T, Jiang C, Zhu Z, Wei W, Zhang L, Wang Q. G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions and inflammation. Cellular Signalling 2022. [DOI: 10.1016/j.cellsig.2022.110337] [Reference Citation Analysis]
31 Echeverría E, Ripoll S, Fabián L, Shayo C, Monczor F, Fernández NC. Novel inhibitors of phosphorylation independent activity of GRK2 modulate cAMP signaling. Pharmacology Res & Perspec 2022;10. [DOI: 10.1002/prp2.913] [Reference Citation Analysis]
32 González-Amor M, Vila-Bedmar R, Rodrigues-Díez R, Moreno-Carriles R, Arcones AC, Cruces-Sande M, Salaices M, Mayor F Jr, Briones AM, Murga C. Myeloid GRK2 Regulates Obesity-Induced Endothelial Dysfunction by Modulating Inflammatory Responses in Perivascular Adipose Tissue. Antioxidants (Basel) 2020;9:E953. [PMID: 33020373 DOI: 10.3390/antiox9100953] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
33 Fu J, Li L, Chen L, Su C, Feng X, Huang K, Zhang L, Yang X, Fu Q. PGE2 protects against heart failure through inhibiting TGF-β1 synthesis in cardiomyocytes and crosstalk between TGF-β1 and GRK2. Journal of Molecular and Cellular Cardiology 2022. [DOI: 10.1016/j.yjmcc.2022.07.012] [Reference Citation Analysis]
34 Sorriento D, Rusciano MR, Visco V, Fiordelisi A, Cerasuolo FA, Poggio P, Ciccarelli M, Iaccarino G. The Metabolic Role of GRK2 in Insulin Resistance and Associated Conditions. Cells 2021;10:167. [PMID: 33467677 DOI: 10.3390/cells10010167] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
35 Zhang Y, Wang S, Huang H, Zeng A, Han Y, Zeng C, Zheng S, Ren H, Wang Y, Huang Y, Jose PA, Ma XL, Zeng C, Chen K. GRK4-mediated adiponectin receptor-1 phosphorylative desensitization as a novel mechanism of reduced renal sodium excretion in hypertension. Clin Sci (Lond) 2020;134:2453-67. [PMID: 32940654 DOI: 10.1042/CS20200671] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
36 Kurose H. Cardiac Fibrosis and Fibroblasts. Cells 2021;10:1716. [PMID: 34359886 DOI: 10.3390/cells10071716] [Reference Citation Analysis]
37 Kang XL, Li YX, Li YL, Wang JX, Zhao XF. The homotetramerization of a GPCR transmits the 20-hydroxyecdysone signal and increases its entry into cells for insect metamorphosis. Development 2021;148:dev196667. [PMID: 33692089 DOI: 10.1242/dev.196667] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
38 Matthees ESF, Haider RS, Hoffmann C, Drube J. Differential Regulation of GPCRs-Are GRK Expression Levels the Key? Front Cell Dev Biol 2021;9:687489. [PMID: 34109182 DOI: 10.3389/fcell.2021.687489] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
39 Jankauskas SS, Kansakar U, Varzideh F, Wilson S, Mone P, Lombardi A, Gambardella J, Santulli G. Heart failure in diabetes. Metabolism 2021;125:154910. [PMID: 34627874 DOI: 10.1016/j.metabol.2021.154910] [Cited by in Crossref: 18] [Cited by in F6Publishing: 13] [Article Influence: 18.0] [Reference Citation Analysis]