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For: Nag SA, Qin JJ, Wang W, Wang MH, Wang H, Zhang R. Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure-Activity Relationships, and Molecular Mechanisms of Action. Front Pharmacol. 2012;3:25. [PMID: 22403544 DOI: 10.3389/fphar.2012.00025] [Cited by in Crossref: 164] [Cited by in F6Publishing: 158] [Article Influence: 16.4] [Reference Citation Analysis]
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3 Mechesso AF, Quah Y, Park SC. Ginsenoside Rg3 reduces the adhesion, invasion, and intracellular survival of Salmonella enterica serovar Typhimurium. J Ginseng Res 2021;45:75-85. [PMID: 33437159 DOI: 10.1016/j.jgr.2019.09.002] [Cited by in Crossref: 1] [Article Influence: 0.3] [Reference Citation Analysis]
4 Liang LD, He T, Du TW, Fan YG, Chen DS, Wang Y. Ginsenoside‑Rg5 induces apoptosis and DNA damage in human cervical cancer cells. Mol Med Rep 2015;11:940-6. [PMID: 25355274 DOI: 10.3892/mmr.2014.2821] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 3.3] [Reference Citation Analysis]
5 Dueregger A, Heidegger I, Ofer P, Perktold B, Ramoner R, Klocker H, Eder IE. The use of dietary supplements to alleviate androgen deprivation therapy side effects during prostate cancer treatment. Nutrients 2014;6:4491-519. [PMID: 25338271 DOI: 10.3390/nu6104491] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 1.5] [Reference Citation Analysis]
6 Li J, Lu J, Ye Z, Han X, Zheng X, Hou H, Chen W, Li X, Zhao L. 20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer. Oncotarget 2017;8:53375-86. [PMID: 28881818 DOI: 10.18632/oncotarget.18482] [Cited by in Crossref: 17] [Cited by in F6Publishing: 19] [Article Influence: 3.4] [Reference Citation Analysis]
7 Yan M, Wang Y, Shen X, Dong S, Diao M, Zhao Y, Zhang T. Enhanced foaming properties of lactoferrin by forming functional complexes with ginsenoside Re and Rb1. Food Hydrocolloids 2022;123:107159. [DOI: 10.1016/j.foodhyd.2021.107159] [Reference Citation Analysis]
8 He B, Chen P, Xie Y, Li S, Zhang X, Yang R, Wang G, Shen Z, Wang H. 20(R)-Ginsenoside Rg3 protects SH-SY5Y cells against apoptosis induced by oxygen and glucose deprivation/reperfusion. Bioorganic & Medicinal Chemistry Letters 2017;27:3867-71. [DOI: 10.1016/j.bmcl.2017.06.045] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
9 Kim JH, Kim M, Yun S, Lee S, No JH, Suh DH, Kim K, Kim YB. Ginsenoside Rh2 induces apoptosis and inhibits epithelial-mesenchymal transition in HEC1A and Ishikawa endometrial cancer cells. Biomedicine & Pharmacotherapy 2017;96:871-6. [DOI: 10.1016/j.biopha.2017.09.033] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.2] [Reference Citation Analysis]
10 Jo S, Lee H, Kim S, Lee CH, Chung H. Korean red ginseng extract induces proliferation to differentiation transition of human acute promyelocytic leukemia cells via MYC-SKP2-CDKN1B axis. Journal of Ethnopharmacology 2013;150:700-7. [DOI: 10.1016/j.jep.2013.09.036] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 0.8] [Reference Citation Analysis]
11 Han S, Jeong AJ, Yang H, Bin Kang K, Lee H, Yi EH, Kim B, Cho C, Chung JW, Sung SH, Ye S. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells. Journal of Ethnopharmacology 2016;194:83-90. [DOI: 10.1016/j.jep.2016.08.039] [Cited by in Crossref: 40] [Cited by in F6Publishing: 35] [Article Influence: 6.7] [Reference Citation Analysis]
12 Qin JJ, Nag S, Voruganti S, Wang W, Zhang R. Natural product MDM2 inhibitors: anticancer activity and mechanisms of action. Curr Med Chem 2012;19:5705-25. [PMID: 22830335 DOI: 10.2174/092986712803988910] [Cited by in Crossref: 35] [Cited by in F6Publishing: 37] [Article Influence: 3.9] [Reference Citation Analysis]
13 Du J, Long F, Chen C. Research Progress on Natural Triterpenoid Saponins in the Chemoprevention and Chemotherapy of Cancer. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids. Elsevier; 2014. pp. 95-130. [DOI: 10.1016/b978-0-12-802215-3.00006-9] [Cited by in Crossref: 18] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
14 Wang X, Su GY, Zhao C, Qu FZ, Wang P, Zhao YQ. Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells. J Ginseng Res 2018;42:133-43. [PMID: 29719459 DOI: 10.1016/j.jgr.2016.12.014] [Cited by in Crossref: 16] [Cited by in F6Publishing: 12] [Article Influence: 2.7] [Reference Citation Analysis]
15 Zhou J, Zhang J, Li J, Guan Y, Shen T, Li F, Li X, Yang X, Hu W. Ginsenoside F2 Suppresses Adipogenesis in 3T3-L1 Cells and Obesity in Mice via the AMPK Pathway. J Agric Food Chem 2021;69:9299-312. [PMID: 34342980 DOI: 10.1021/acs.jafc.1c03420] [Reference Citation Analysis]
16 Chen S, Wang Z, Huang Y, O'Barr SA, Wong RA, Yeung S, Chow MS. Ginseng and anticancer drug combination to improve cancer chemotherapy: a critical review. Evid Based Complement Alternat Med 2014;2014:168940. [PMID: 24876866 DOI: 10.1155/2014/168940] [Cited by in Crossref: 23] [Cited by in F6Publishing: 23] [Article Influence: 2.9] [Reference Citation Analysis]
17 Liu W, Wang S, Yang Q, Feng X, Yu B, Yu X. 20(s)-ginsenoside Rh2 promotes TRAIL-induced apoptosis by upregulating DR5 in human hepatocellular carcinoma cells. Med Oncol 2022;39:70. [PMID: 35568793 DOI: 10.1007/s12032-022-01663-6] [Reference Citation Analysis]
18 Xin C, Kim J, Quan H, Yin M, Jeong S, Choi JI, Jang EA, Lee CH, Kim DH, Bae HB. Ginsenoside Rg3 promotes Fc gamma receptor-mediated phagocytosis of bacteria by macrophages via an extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent mechanism. Int Immunopharmacol 2019;77:105945. [PMID: 31644962 DOI: 10.1016/j.intimp.2019.105945] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 2.7] [Reference Citation Analysis]
19 Zhu Y, Liang J, Gao C, Wang A, Xia J, Hong C, Zhong Z, Zuo Z, Kim J, Ren H, Li S, Wang Q, Zhang F, Wang J. Multifunctional ginsenoside Rg3-based liposomes for glioma targeting therapy. Journal of Controlled Release 2021;330:641-57. [DOI: 10.1016/j.jconrel.2020.12.036] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
20 Ma Z, Mi Y, Han X, Li H, Tian M, Duan Z, Fan D, Ma P. Transformation of ginsenoside via deep eutectic solvents based on choline chloride as an enzymatic reaction medium. Bioprocess Biosyst Eng 2020;43:1195-208. [DOI: 10.1007/s00449-020-02314-8] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
21 Gwak YS, Han JY, Choi YE. Production of ginsenoside aglycone (protopanaxatriol) and male sterility of transgenic tobacco co-overexpressing three Panax ginseng genes: PgDDS, CYP716A47, and CYP716A53v2. J Ginseng Res 2019;43:261-71. [PMID: 30976164 DOI: 10.1016/j.jgr.2018.02.005] [Cited by in Crossref: 4] [Article Influence: 1.3] [Reference Citation Analysis]
22 Lee JO, Kim JH, Kim S, Kim MY, Hong YH, Kim HG, Cho JY. Gastroprotective effects of the nonsaponin fraction of Korean Red Ginseng through cyclooxygenase-1 upregulation. J Ginseng Res 2020;44:655-63. [PMID: 32617046 DOI: 10.1016/j.jgr.2019.11.001] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 3.7] [Reference Citation Analysis]
23 Siddiqi MZ, Ximenes HA, Song BK, Park HY, Lee WH, Han H, Im WT. Enhanced production of ginsenoside Rh2(S) from PPD-type major ginsenosides using BglSk cloned from Saccharibacillus kuerlensis together with two glycosidase in series. Saudi J Biol Sci 2021;28:4668-76. [PMID: 34354454 DOI: 10.1016/j.sjbs.2021.04.079] [Reference Citation Analysis]
24 Phi LTH, Wijaya YT, Sari IN, Kim KS, Yang YG, Lee MW, Kwon HY. 20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis. Onco Targets Ther 2019;12:10885-95. [PMID: 31849492 DOI: 10.2147/OTT.S219063] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.7] [Reference Citation Analysis]
25 Kim JH, Choi J. Effect of Ginsenoside Rh-2 via Activation of Caspase-3 and Bcl-2-Insensitive Pathway in Ovarian Cancer Cells. Physiol Res. [DOI: 10.33549/physiolres.933367] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.5] [Reference Citation Analysis]
26 Yan YB, Tian Q, Zhang JF, Xiang Y. Antitumor effects and molecular mechanisms of action of natural products in ovarian cancer. Oncol Lett 2020;20:141. [PMID: 32934709 DOI: 10.3892/ol.2020.12001] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
27 Zhang X, Zhang S, Sun Q, Jiao W, Yan Y, Zhang X. Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3. Molecules. 2018;23:pii: E1482. [PMID: 29921768 DOI: 10.3390/molecules23061482] [Cited by in Crossref: 19] [Cited by in F6Publishing: 20] [Article Influence: 4.8] [Reference Citation Analysis]
28 Phi LTH, Wijaya YT, Sari IN, Yang YG, Lee YK, Kwon HY. The anti-metastatic effect of ginsenoside Rb2 in colorectal cancer in an EGFR/SOX2-dependent manner. Cancer Med 2018;7:5621-31. [PMID: 30264477 DOI: 10.1002/cam4.1800] [Cited by in Crossref: 8] [Cited by in F6Publishing: 10] [Article Influence: 2.0] [Reference Citation Analysis]
29 Chu Y, Zhang W, Kanimozhi G, Brindha GR, Tian D. Ginsenoside Rg1 Induces Apoptotic Cell Death in Triple-Negative Breast Cancer Cell Lines and Prevents Carcinogen-Induced Breast Tumorigenesis in Sprague Dawley Rats. Evid Based Complement Alternat Med 2020;2020:8886955. [PMID: 33178325 DOI: 10.1155/2020/8886955] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
30 Pu J, Akter R, Rupa EJ, Awais M, Mathiyalagan R, Han Y, Kang J, Yang DC, Kang SC. Role of Ginsenosides in Browning of White Adipose Tissue to Combat Obesity: A Narrative Review on Molecular Mechanism. Archives of Medical Research 2021. [DOI: 10.1016/j.arcmed.2021.11.003] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
31 Im DS, Nah SY. Yin and Yang of ginseng pharmacology: ginsenosides vs gintonin. Acta Pharmacol Sin 2013;34:1367-73. [PMID: 24122014 DOI: 10.1038/aps.2013.100] [Cited by in Crossref: 56] [Cited by in F6Publishing: 44] [Article Influence: 6.2] [Reference Citation Analysis]
32 Im DS. Pro-Resolving Effect of Ginsenosides as an Anti-Inflammatory Mechanism of Panax ginseng. Biomolecules 2020;10:E444. [PMID: 32183094 DOI: 10.3390/biom10030444] [Cited by in Crossref: 18] [Cited by in F6Publishing: 10] [Article Influence: 9.0] [Reference Citation Analysis]
33 Li KK, Li SS, Xu F, Gong XJ. Six new dammarane-type triterpene saponins from Panax ginseng flower buds and their cytotoxicity. J Ginseng Res 2020;44:215-21. [PMID: 32148402 DOI: 10.1016/j.jgr.2018.12.008] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
34 Lee JH, Lim H, Shehzad O, Kim YS, Kim HP. Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation. Eur J Pharmacol 2014;724:145-51. [PMID: 24384406 DOI: 10.1016/j.ejphar.2013.12.035] [Cited by in Crossref: 24] [Cited by in F6Publishing: 21] [Article Influence: 2.7] [Reference Citation Analysis]
35 Gurău F, Baldoni S, Prattichizzo F, Espinosa E, Amenta F, Procopio AD, Albertini MC, Bonafè M, Olivieri F. Anti-senescence compounds: A potential nutraceutical approach to healthy aging. Ageing Res Rev 2018;46:14-31. [PMID: 29742452 DOI: 10.1016/j.arr.2018.05.001] [Cited by in Crossref: 92] [Cited by in F6Publishing: 71] [Article Influence: 23.0] [Reference Citation Analysis]
36 Voruganti S, Qin JJ, Sarkar S, Nag S, Walbi IA, Wang S, Zhao Y, Wang W, Zhang R. Oral nano-delivery of anticancer ginsenoside 25-OCH3-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action. Oncotarget 2015;6:21379-94. [PMID: 26041888 DOI: 10.18632/oncotarget.4091] [Cited by in Crossref: 41] [Cited by in F6Publishing: 41] [Article Influence: 6.8] [Reference Citation Analysis]
37 Zare-Zardini H, Alemi A, Taheri-Kafrani A, Hosseini SA, Soltaninejad H, Hamidieh AA, Haghi Karamallah M, Farrokhifar M, Farrokhifar M. Assessment of a New Ginsenoside Rh2 Nanoniosomal Formulation for Enhanced Antitumor Efficacy on Prostate Cancer: An in vitro Study. Drug Des Devel Ther 2020;14:3315-24. [PMID: 32884236 DOI: 10.2147/DDDT.S261027] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
38 An W, Lai H, Zhang Y, Liu M, Lin X, Cao S. Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese Medicines. Front Pharmacol 2019;10:758. [PMID: 31354479 DOI: 10.3389/fphar.2019.00758] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 6.0] [Reference Citation Analysis]
39 Oh J, Jeon SB, Lee Y, Lee H, Kim J, Kwon BR, Yu K, Cha J, Hwang S, Choi K, Jeong Y. Fermented Red Ginseng Extract Inhibits Cancer Cell Proliferation and Viability. Journal of Medicinal Food 2015;18:421-8. [DOI: 10.1089/jmf.2014.3248] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 3.0] [Reference Citation Analysis]
40 Le TH, Lee SY, Kim TR, Kim JY, Kwon SW, Nguyen NK, Park JH, Nguyen MD. Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity. J Ginseng Res 2014;38:154-9. [PMID: 24748840 DOI: 10.1016/j.jgr.2013.11.015] [Cited by in Crossref: 28] [Cited by in F6Publishing: 22] [Article Influence: 3.1] [Reference Citation Analysis]
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42 Oh J, Yoon HJ, Jang JH, Kim DH, Surh YJ. The standardized Korean Red Ginseng extract and its ingredient ginsenoside Rg3 inhibit manifestation of breast cancer stem cell-like properties through modulation of self-renewal signaling. J Ginseng Res 2019;43:421-30. [PMID: 31308814 DOI: 10.1016/j.jgr.2018.05.004] [Cited by in Crossref: 15] [Cited by in F6Publishing: 10] [Article Influence: 3.8] [Reference Citation Analysis]
43 Sodrul IMD, Wang C, Chen X, Du J, Sun H. Role of ginsenosides in reactive oxygen species-mediated anticancer therapy. Oncotarget 2018;9:2931-50. [PMID: 29416826 DOI: 10.18632/oncotarget.23407] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 4.0] [Reference Citation Analysis]
44 Li XF, Zhao GQ, Li LY. Ginsenoside impedes proliferation and induces apoptosis of human osteosarcoma cells by down-regulating β-catenin. Cancer Biomark 2019;24:395-404. [PMID: 30909183 DOI: 10.3233/CBM-182046] [Reference Citation Analysis]
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46 Ali MY, Zaib S, Jannat S, Khan I. Inhibition of Angiotensin-I Converting Enzyme by Ginsenosides: Structure-Activity Relationships and Inhibitory Mechanism. J Agric Food Chem 2021;69:6073-86. [PMID: 34014666 DOI: 10.1021/acs.jafc.1c01231] [Reference Citation Analysis]
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49 Li KR, Zhang ZQ, Yao J, Zhao YX, Duan J, Cao C, Jiang Q. Ginsenoside Rg-1 protects retinal pigment epithelium (RPE) cells from cobalt chloride (CoCl2) and hypoxia assaults. PLoS One 2013;8:e84171. [PMID: 24386346 DOI: 10.1371/journal.pone.0084171] [Cited by in Crossref: 37] [Cited by in F6Publishing: 38] [Article Influence: 4.1] [Reference Citation Analysis]
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55 Park S, Ko E, Lee JH, Song Y, Cui CH, Hou J, Jeon BM, Kim HS, Kim SC. Gypenoside LXXV Promotes Cutaneous Wound Healing In Vivo by Enhancing Connective Tissue Growth Factor Levels Via the Glucocorticoid Receptor Pathway. Molecules 2019;24:E1595. [PMID: 31018484 DOI: 10.3390/molecules24081595] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 2.3] [Reference Citation Analysis]
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57 Chen X, Wang M, Xu X, Liu J, Mei B, Fu P, Zhao D, Sun L. Panax ginseng total protein promotes proliferation and secretion of collagen in NIH/3T3 cells by activating extracellular signal-related kinase pathway. J Ginseng Res 2017;41:411-8. [PMID: 28701885 DOI: 10.1016/j.jgr.2017.02.001] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 2.2] [Reference Citation Analysis]
58 Koczurkiewicz P, Podolak I, Skrzeczyńska-Moncznik J, Sarna M, Wójcik KA, Ryszawy D, Galanty A, Lasota S, Madeja Z, Czyż J, Michalik M. Triterpene saponosides from Lysimachia ciliata differentially attenuate invasive potential of prostate cancer cells. Chem Biol Interact 2013;206:6-17. [PMID: 23954719 DOI: 10.1016/j.cbi.2013.08.003] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
59 Qu Q, Yang F, Zhao C, Liu X, Yang P, Li Z, Han L, Shi X. Effects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea. J Ethnopharmacol 2021;267:113594. [PMID: 33217518 DOI: 10.1016/j.jep.2020.113594] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
60 Saba E, Irfan M, Jeong D, Ameer K, Lee YY, Park CK, Hong SB, Rhee MH. Mediation of antiinflammatory effects of Rg3-enriched red ginseng extract from Korean Red Ginseng via retinoid X receptor α-peroxisome-proliferating receptor γ nuclear receptors. J Ginseng Res 2019;43:442-51. [PMID: 31308816 DOI: 10.1016/j.jgr.2018.06.005] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
61 Wang W, Liu J, Xin Y, He T, Qiu Y, Qu M, Song Y, Qiu Z. Highly regioselective bioconversion of ginsenoside Re into 20(S/R)-Rf2 by an optimized culture of Cordyceps sinensis. New J Chem 2020;44:14005-14. [DOI: 10.1039/d0nj01828g] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
62 Dai L, Zhu W, Si C, Lei J. "Nano-Ginseng" for Enhanced Cytotoxicity AGAINST Cancer Cells. Int J Mol Sci 2018;19:E627. [PMID: 29473838 DOI: 10.3390/ijms19020627] [Cited by in Crossref: 8] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
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