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For: Coward J, Harding A. Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer. Front Oncol 2014;4:123. [PMID: 24904834 DOI: 10.3389/fonc.2014.00123] [Cited by in Crossref: 102] [Cited by in F6Publishing: 99] [Article Influence: 12.8] [Reference Citation Analysis]
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11 Mirzayans R, Murray D. Do TUNEL and Other Apoptosis Assays Detect Cell Death in Preclinical Studies? Int J Mol Sci 2020;21:E9090. [PMID: 33260475 DOI: 10.3390/ijms21239090] [Cited by in Crossref: 6] [Cited by in F6Publishing: 8] [Article Influence: 3.0] [Reference Citation Analysis]
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13 Mirzayans R, Andrais B, Murray D. Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents? Int J Mol Sci 2017;18:E1679. [PMID: 28767065 DOI: 10.3390/ijms18081679] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 2.0] [Reference Citation Analysis]
14 Chiang JL, Yang YW. Modulation of the anticancer activities of paclitaxel by Cremophor micelles. Int J Pharm 2021;603:120699. [PMID: 33992713 DOI: 10.1016/j.ijpharm.2021.120699] [Reference Citation Analysis]
15 Donne R, Saroul-Aïnama M, Cordier P, Celton-Morizur S, Desdouets C. Polyploidy in liver development, homeostasis and disease. Nat Rev Gastroenterol Hepatol 2020;17:391-405. [PMID: 32242122 DOI: 10.1038/s41575-020-0284-x] [Cited by in Crossref: 33] [Cited by in F6Publishing: 31] [Article Influence: 16.5] [Reference Citation Analysis]
16 Sikora E, Czarnecka-herok J, Bojko A, Sunderland P. Therapy-induced polyploidization and senescence: Coincidence or interconnection? Seminars in Cancer Biology 2020. [DOI: 10.1016/j.semcancer.2020.11.015] [Cited by in Crossref: 9] [Cited by in F6Publishing: 11] [Article Influence: 4.5] [Reference Citation Analysis]
17 Ozawa H, Imazeki H, Ogiwara Y, Kawakubo H, Fukuda K, Kitagawa Y, Kudo-Saito C. Targeting AURKA in treatment of peritoneal tumor dissemination in gastrointestinal cancer. Transl Oncol 2021;16:101307. [PMID: 34902741 DOI: 10.1016/j.tranon.2021.101307] [Reference Citation Analysis]
18 Fan Y, Zhang G, Zhao K, Fu W, Chen S, Liu J, Liu W, Peng L, Ren L, Liu S, Xiao Y. Characteristics of SP600125 Induced Tetraploid Cells in Comparison With Diploid and Tetraploid Cells of Fish. Front Genet 2021;12:781007. [PMID: 34938322 DOI: 10.3389/fgene.2021.781007] [Reference Citation Analysis]
19 Willison KR. The structure and evolution of eukaryotic chaperonin-containing TCP-1 and its mechanism that folds actin into a protein spring. Biochemical Journal 2018;475:3009-34. [DOI: 10.1042/bcj20170378] [Cited by in Crossref: 17] [Cited by in F6Publishing: 10] [Article Influence: 4.3] [Reference Citation Analysis]
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21 Mosieniak G, Sliwinska MA, Alster O, Strzeszewska A, Sunderland P, Piechota M, Was H, Sikora E. Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence. Neoplasia 2015;17:882-93. [PMID: 26696370 DOI: 10.1016/j.neo.2015.11.008] [Cited by in Crossref: 68] [Cited by in F6Publishing: 67] [Article Influence: 11.3] [Reference Citation Analysis]
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23 Galofré C, Gönül Geyik Ö, Asensio E, Wangsa D, Hirsch D, Parra C, Saez J, Mollà M, Yüce Z, Castells A, Ried T, Camps J. Tetraploidy-Associated Genetic Heterogeneity Confers Chemo-Radiotherapy Resistance to Colorectal Cancer Cells. Cancers (Basel) 2020;12:E1118. [PMID: 32365785 DOI: 10.3390/cancers12051118] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
24 Erenpreisa J, Salmina K, Huna A, Jackson TR, Vazquez-Martin A, Cragg MS. The "virgin birth", polyploidy, and the origin of cancer. Oncoscience 2015;2:3-14. [PMID: 25821840 DOI: 10.18632/oncoscience.108] [Cited by in Crossref: 40] [Cited by in F6Publishing: 36] [Article Influence: 5.0] [Reference Citation Analysis]
25 Gjelsvik KJ, Besen-McNally R, Losick VP. Solving the Polyploid Mystery in Health and Disease. Trends Genet 2019;35:6-14. [PMID: 30470486 DOI: 10.1016/j.tig.2018.10.005] [Cited by in Crossref: 27] [Cited by in F6Publishing: 22] [Article Influence: 6.8] [Reference Citation Analysis]
26 White-Gilbertson S, Lu P, Jones CM, Chiodini S, Hurley D, Das A, Delaney JR, Norris JS, Voelkel-Johnson C. Tamoxifen is a candidate first-in-class inhibitor of acid ceramidase that reduces amitotic division in polyploid giant cancer cells-Unrecognized players in tumorigenesis. Cancer Med 2020;9:3142-52. [PMID: 32135040 DOI: 10.1002/cam4.2960] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 7.0] [Reference Citation Analysis]
27 Shenk EM, Ganem NJ. Generation and Purification of Tetraploid Cells. Methods Mol Biol 2016;1413:393-401. [PMID: 27193862 DOI: 10.1007/978-1-4939-3542-0_24] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
28 Lin KC, Torga G, Sun Y, Axelrod R, Pienta KJ, Sturm JC, Austin RH. The role of heterogeneous environment and docetaxel gradient in the emergence of polyploid, mesenchymal and resistant prostate cancer cells. Clin Exp Metastasis 2019;36:97-108. [PMID: 30810874 DOI: 10.1007/s10585-019-09958-1] [Cited by in Crossref: 26] [Cited by in F6Publishing: 24] [Article Influence: 8.7] [Reference Citation Analysis]
29 Bowers RR, Andrade MF, Jones CM, White-gilbertson S, Voelkel-johnson C, Delaney JR. Autophagy modulating therapeutics inhibit ovarian cancer colony generation by polyploid giant cancer cells (PGCCs). BMC Cancer 2022;22. [DOI: 10.1186/s12885-022-09503-6] [Reference Citation Analysis]
30 Gomes CJ, Centuori SM, Harman MW, Putnam CW, Wolgemuth CW, Martinez JD. The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ. Genes Cancer 2017;8:771-83. [PMID: 29321819 DOI: 10.18632/genesandcancer.161] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.4] [Reference Citation Analysis]
31 Van de Peer Y, Mizrachi E, Marchal K. The evolutionary significance of polyploidy. Nat Rev Genet 2017;18:411-24. [PMID: 28502977 DOI: 10.1038/nrg.2017.26] [Cited by in Crossref: 550] [Cited by in F6Publishing: 401] [Article Influence: 110.0] [Reference Citation Analysis]
32 Yant L, Bomblies K. Genome management and mismanagement--cell-level opportunities and challenges of whole-genome duplication. Genes Dev 2015;29:2405-19. [PMID: 26637526 DOI: 10.1101/gad.271072.115] [Cited by in Crossref: 23] [Cited by in F6Publishing: 15] [Article Influence: 3.8] [Reference Citation Analysis]
33 Thomson GJ, Hernon C, Austriaco N, Shapiro RS, Belenky P, Bennett RJ. Metabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells. EMBO J 2019;38:e101597. [PMID: 31448850 DOI: 10.15252/embj.2019101597] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 5.7] [Reference Citation Analysis]
34 Farina AR, Cappabianca LA, Zelli V, Sebastiano M, Mackay AR. Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting. World J Stem Cells 2021; 13(7): 685-736 [PMID: 34367474 DOI: 10.4252/wjsc.v13.i7.685] [Reference Citation Analysis]
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36 Raveh E, Matouk IJ, Gilon M, Hochberg A. The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theory. Mol Cancer. 2015;14:184. [PMID: 26536864 DOI: 10.1186/s12943-015-0458-2] [Cited by in Crossref: 302] [Cited by in F6Publishing: 308] [Article Influence: 43.1] [Reference Citation Analysis]
37 Ren D, Song J, Ni M, Kang L, Guo W. Regulatory Mechanisms of Cell Polyploidy in Insects. Front Cell Dev Biol 2020;8:361. [PMID: 32548115 DOI: 10.3389/fcell.2020.00361] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
38 Mirzayans R, Andrais B, Murray D. Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment. Cancers (Basel) 2018;10:E118. [PMID: 29662021 DOI: 10.3390/cancers10040118] [Cited by in Crossref: 67] [Cited by in F6Publishing: 61] [Article Influence: 16.8] [Reference Citation Analysis]
39 Loreth D, Schuette M, Zinke J, Mohme M, Piffko A, Schneegans S, Stadler J, Janning M, Loges S, Joosse SA, Lamszus K, Westphal M, Müller V, Glatzel M, Matschke J, Gebhardt C, Schneider SW, Belczacka I, Volkmer B, Greinert R, Yaspo ML, Harter PN, Pantel K, Wikman H. CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis. Int J Mol Sci 2021;22:6993. [PMID: 34209696 DOI: 10.3390/ijms22136993] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
40 He Q, Au B, Kulkarni M, Shen Y, Lim KJ, Maimaiti J, Wong CK, Luijten MNH, Chong HC, Lim EH, Rancati G, Sinha I, Fu Z, Wang X, Connolly JE, Crasta KC. Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects. Oncogenesis 2018;7:62. [PMID: 30108207 DOI: 10.1038/s41389-018-0072-4] [Cited by in Crossref: 20] [Cited by in F6Publishing: 20] [Article Influence: 5.0] [Reference Citation Analysis]
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42 Mirzayans R, Murray D. Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence. Int J Mol Sci 2020;21:E1308. [PMID: 32075223 DOI: 10.3390/ijms21041308] [Cited by in Crossref: 18] [Cited by in F6Publishing: 19] [Article Influence: 9.0] [Reference Citation Analysis]
43 Raftopoulou C, Roumelioti FM, Dragona E, Gimelli S, Sloan-Béna F, Gorgoulis V, Antonarakis SE, Gagos S. Karyotypic Flexibility of the Complex Cancer Genome and the Role of Polyploidization in Maintenance of Structural Integrity of Cancer Chromosomes. Cancers (Basel) 2020;12:E591. [PMID: 32150835 DOI: 10.3390/cancers12030591] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
44 Almengló C, Caamaño P, Fraga M, Devesa J, Costoya JA, Arce VM. From neural stem cells to glioblastoma: A natural history of GBM recapitulated in vitro. J Cell Physiol 2021. [PMID: 33959982 DOI: 10.1002/jcp.30409] [Reference Citation Analysis]
45 Moein S, Adibi R, da Silva Meirelles L, Nardi NB, Gheisari Y. Cancer regeneration: Polyploid cells are the key drivers of tumor progression. Biochim Biophys Acta Rev Cancer. 2020;1874:188408. [PMID: 32827584 DOI: 10.1016/j.bbcan.2020.188408] [Cited by in Crossref: 10] [Cited by in F6Publishing: 12] [Article Influence: 5.0] [Reference Citation Analysis]
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47 Lazebnik Y. The shock of being united and symphiliosis. Another lesson from plants? Cell Cycle 2014;13:2323-9. [PMID: 25483182 DOI: 10.4161/cc.29704] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 1.6] [Reference Citation Analysis]
48 Binan L, Bélanger F, Uriarte M, Lemay JF, Pelletier De Koninck JC, Roy J, Affar EB, Drobetsky E, Wurtele H, Costantino S. Opto-magnetic capture of individual cells based on visual phenotypes. Elife 2019;8:e45239. [PMID: 30969169 DOI: 10.7554/eLife.45239] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.7] [Reference Citation Analysis]
49 de Castro E Gloria H, Jesuíno Nogueira L, Bencke Grudzinski P, da Costa Ghignatti PV, Guecheva TN, Motta Leguisamo N, Saffi J. Olaparib-mediated enhancement of 5-fluorouracil cytotoxicity in mismatch repair deficient colorectal cancer cells. BMC Cancer 2021;21:448. [PMID: 33888065 DOI: 10.1186/s12885-021-08188-7] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
50 Pienta KJ, Hammarlund EU, Austin RH, Axelrod R, Brown JS, Amend SR. Cancer cells employ an evolutionarily conserved polyploidization program to resist therapy. Semin Cancer Biol 2020:S1044-579X(20)30254-6. [PMID: 33276091 DOI: 10.1016/j.semcancer.2020.11.016] [Cited by in Crossref: 4] [Cited by in F6Publishing: 9] [Article Influence: 2.0] [Reference Citation Analysis]
51 Mahadevan D, Rogers GC. Janus Face of Drug-Induced Tetraploidy in Non-Hodgkin Lymphoma. Trends Cancer 2020;6:627-30. [PMID: 32291237 DOI: 10.1016/j.trecan.2020.03.009] [Reference Citation Analysis]
52 Obara EAA, Aguilar-Morante D, Rasmussen RD, Frias A, Vitting-Serup K, Lim YC, Elbæk KJ, Pedersen H, Vardouli L, Jensen KE, Skjoth-Rasmussen J, Brennum J, Tuckova L, Strauss R, Dinant C, Bartek J, Hamerlik P. SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells. Nat Commun 2020;11:4709. [PMID: 32948765 DOI: 10.1038/s41467-020-18549-8] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
53 Fang Z, Lagier M, Méresse S. Production of Murine Macrophages from Hoxb8-Immortalized Myeloblasts: Utility and Use in the Context of Salmonella Infection. Methods Mol Biol 2021;2182:117-26. [PMID: 32894491 DOI: 10.1007/978-1-0716-0791-6_11] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
54 Candiota AP, Arús C. Establishing Imaging Biomarkers of Host Immune System Efficacy during Glioblastoma Therapy Response: Challenges, Obstacles and Future Perspectives. Metabolites 2022;12:243. [DOI: 10.3390/metabo12030243] [Reference Citation Analysis]
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56 Zarghami N, Murrell DH, Jensen MD, Dick FA, Chambers AF, Foster PJ, Wong E. Half brain irradiation in a murine model of breast cancer brain metastasis: magnetic resonance imaging and histological assessments of dose-response. Radiat Oncol 2018;13:104. [PMID: 29859114 DOI: 10.1186/s13014-018-1028-8] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
57 Arif KMT, Elliott EK, Haupt LM, Griffiths LR. Regulatory Mechanisms of Epigenetic miRNA Relationships in Human Cancer and Potential as Therapeutic Targets. Cancers (Basel) 2020;12:E2922. [PMID: 33050637 DOI: 10.3390/cancers12102922] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 7.5] [Reference Citation Analysis]
58 Gemble S, Basto R. CHRONOCRISIS: When Cell Cycle Asynchrony Generates DNA Damage in Polyploid Cells. Bioessays 2020;42:e2000105. [PMID: 32885500 DOI: 10.1002/bies.202000105] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
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