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7 Gerisch M, Heinig R, Engelen A, Lang D, Kolkhof P, Radtke M, Platzek J, Lovis K, Rohde G, Schwarz T. Biotransformation of Finerenone, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, in Dogs, Rats, and Humans, In Vivo and In Vitro. Drug Metab Dispos 2018;46:1546-55. [PMID: 30171161 DOI: 10.1124/dmd.118.083337] [Cited by in Crossref: 14] [Cited by in F6Publishing: 5] [Article Influence: 4.7] [Reference Citation Analysis]
8 Taub ME, Ludwig-Schwellinger E, Ishiguro N, Kishimoto W, Yu H, Wagner K, Tweedie D. Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species. Chem Res Toxicol 2015;28:103-15. [PMID: 25489797 DOI: 10.1021/tx500380t] [Cited by in Crossref: 20] [Cited by in F6Publishing: 16] [Article Influence: 3.3] [Reference Citation Analysis]
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10 Yun J, Yoon J, Kang B, Cho N, Seok SH, Min S, Min JH, Che J, Kim YK. The toxicity and distribution of iron oxide-zinc oxide core-shell nanoparticles in C57BL/6 mice after repeated subcutaneous administration: Toxicity and distribution of Fe 3 O 4 -ZnO core-shell nanoparticles. J Appl Toxicol 2015;35:593-602. [DOI: 10.1002/jat.3102] [Cited by in Crossref: 15] [Cited by in F6Publishing: 12] [Article Influence: 2.5] [Reference Citation Analysis]
11 Grime K, Webborn PJH, Riley RJ. Functional Consequences of Active Hepatic Uptake on Cytochrome P450 Inhibition in Rat and Human Hepatocytes. Drug Metab Dispos 2008;36:1670-8. [DOI: 10.1124/dmd.108.021055] [Cited by in Crossref: 26] [Cited by in F6Publishing: 22] [Article Influence: 2.0] [Reference Citation Analysis]
12 Van der Ven LT, van de Kuil T, Leonards PE, Slob W, Cantón RF, Germer S, Visser TJ, Litens S, Håkansson H, Schrenk D, van den Berg M, Piersma AH, Vos JG, Opperhuizen A. A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE). Toxicology Letters 2008;179:6-14. [DOI: 10.1016/j.toxlet.2008.03.003] [Cited by in Crossref: 40] [Cited by in F6Publishing: 33] [Article Influence: 3.1] [Reference Citation Analysis]
13 Marumoto S, Oda Y, Miyazawa M. Antigenotoxic activity of naturally occurring furanocoumarins. Environ Mol Mutagen 2011;52:646-57. [DOI: 10.1002/em.20665] [Cited by in Crossref: 13] [Cited by in F6Publishing: 9] [Article Influence: 1.3] [Reference Citation Analysis]
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15 Clayton NP, Yoshizawa K, Kissling GE, Burka LT, Chan PC, Nyska A. Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract. Exp Toxicol Pathol 2007;58:223-36. [PMID: 17059882 DOI: 10.1016/j.etp.2006.08.002] [Cited by in Crossref: 38] [Cited by in F6Publishing: 27] [Article Influence: 2.5] [Reference Citation Analysis]
16 Park E, Ko G, Kim J, Sohn DH. Biotransformation of theophylline in cirrhotic rats induced by biliary obstruction. Arch Pharm Res 1999;22:60-7. [DOI: 10.1007/bf02976437] [Cited by in Crossref: 5] [Article Influence: 0.2] [Reference Citation Analysis]
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18 Hirao J, Arakawa S, Watanabe K, Ito K, Furukawa T. Effects of restricted feeding on daily fluctuations of hepatic functions including p450 monooxygenase activities in rats. J Biol Chem 2006;281:3165-71. [PMID: 16332680 DOI: 10.1074/jbc.M511194200] [Cited by in Crossref: 22] [Cited by in F6Publishing: 7] [Article Influence: 1.4] [Reference Citation Analysis]
19 N'guessan BB, Amponsah SK, Dugbartey GJ, Awuah KD, Dotse E, Aning A, Kukuia KKE, Asiedu-Gyekye IJ, Appiah-Opong R. In Vitro Antioxidant Potential and Effect of a Glutathione-Enhancer Dietary Supplement on Selected Rat Liver Cytochrome P450 Enzyme Activity. Evid Based Complement Alternat Med 2018;2018:7462839. [PMID: 29977317 DOI: 10.1155/2018/7462839] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 1.3] [Reference Citation Analysis]
20 Schmitz A, Demmel S, Peters LM, Leeb T, Mevissen M, Haase B. Comparative human-horse sequence analysis of the CYP3A subfamily gene cluster: Comparative human-horse sequence analysis. Animal Genetics 2010;41:72-9. [DOI: 10.1111/j.1365-2052.2010.02111.x] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 1.3] [Reference Citation Analysis]
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22 Margalef M, Pons Z, Iglesias-carres L, Arola L, Muguerza B, Arola-arnal A. Gender-related similarities and differences in the body distribution of grape seed flavanols in rats. Mol Nutr Food Res 2016;60:760-72. [DOI: 10.1002/mnfr.201500717] [Cited by in Crossref: 32] [Cited by in F6Publishing: 22] [Article Influence: 6.4] [Reference Citation Analysis]
23 Simpson J, Ryan C, Curley A, Mulcaire J, Kelly JP. Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests. Prog Neuropsychopharmacol Biol Psychiatry 2012;37:227-36. [PMID: 22353173 DOI: 10.1016/j.pnpbp.2012.02.004] [Cited by in Crossref: 64] [Cited by in F6Publishing: 51] [Article Influence: 7.1] [Reference Citation Analysis]
24 Quintieri L, Fantin M, Palatini P, De Martin S, Rosato A, Caruso M, Geroni C, Floreani M. In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: A comparison with human liver microsomes. Biochemical Pharmacology 2008;76:784-95. [DOI: 10.1016/j.bcp.2008.07.003] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 1.2] [Reference Citation Analysis]
25 Johnson KA, Prakash C. METABOLISM, EXCRETION, AND PHARMACOKINETICS OF (3-{[4- TERT -BUTYL-BENZYL)-(PYRIDINE-3-SULFONYL)-AMINO]-METHYL}-PHENOXY)-ACETIC ACID, AN EP2 RECEPTOR-SELECTIVE PROSTAGLANDIN E2 AGONIST, IN MALE AND FEMALE SPRAGUE-DAWLEY RATS. Drug Metab Dispos 2005;33:1191-201. [DOI: 10.1124/dmd.105.004713] [Cited by in Crossref: 5] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
26 Patel NN, Crincoli CM, Frederick DM, Tchao R, Harvison PJ. Effect of structural modifications on 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione-induced hepatotoxicity in Fischer 344 rats. J Appl Toxicol 2012;32:108-17. [PMID: 21337588 DOI: 10.1002/jat.1639] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
27 Maronpot RR, Yoshizawa K, Nyska A, Harada T, Flake G, Mueller G, Singh B, Ward JM. Hepatic Enzyme Induction: Histopathology. Toxicol Pathol 2010;38:776-95. [DOI: 10.1177/0192623310373778] [Cited by in Crossref: 113] [Cited by in F6Publishing: 82] [Article Influence: 10.3] [Reference Citation Analysis]
28 Ohyama K, Maki S, Sato K, Kato Y. Comparative in vitro metabolism of the suspected pro-oestrogenic compound, methoxychlor in precision-cut liver slices from male and female rats. Xenobiotica 2008;35:331-42. [DOI: 10.1080/00498250500087309] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
29 Bartholomaeus A, Parrott W, Bondy G, Walker K; ILSI International Food Biotechnology Committee Task Force on Use of Mammalian Toxicology Studies in Safety Assessment of GM Foods. The use of whole food animal studies in the safety assessment of genetically modified crops: limitations and recommendations. Crit Rev Toxicol 2013;43 Suppl 2:1-24. [PMID: 24164514 DOI: 10.3109/10408444.2013.842955] [Cited by in Crossref: 39] [Cited by in F6Publishing: 24] [Article Influence: 5.6] [Reference Citation Analysis]
30 Melia T, Waxman DJ. Genetic factors contributing to extensive variability of sex-specific hepatic gene expression in Diversity Outbred mice. PLoS One 2020;15:e0242665. [PMID: 33264334 DOI: 10.1371/journal.pone.0242665] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
31 Bano F, Mohanty B. Thyroid disrupting pesticides mancozeb and fipronil in mixture caused oxidative damage and genotoxicity in lymphoid organs of mice. Environmental Toxicology and Pharmacology 2020;79:103408. [DOI: 10.1016/j.etap.2020.103408] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
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33 Hosoe K, Kitano M, Kishida H, Kubo H, Fujii K, Kitahara M. Study on safety and bioavailability of ubiquinol (Kaneka QH™) after single and 4-week multiple oral administration to healthy volunteers. Regulatory Toxicology and Pharmacology 2007;47:19-28. [DOI: 10.1016/j.yrtph.2006.07.001] [Cited by in Crossref: 89] [Cited by in F6Publishing: 58] [Article Influence: 6.4] [Reference Citation Analysis]
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37 Baker JR, Satarug S, Reilly PE, Edwards RJ, Ariyoshi N, Kamataki T, Moore MR, Williams DJ. Relationships between non-occupational cadmium exposure and expression of nine cytochrome P450 forms in human liver and kidney cortex samples. Biochem Pharmacol. 2001;62:713-721. [PMID: 11551516 DOI: 10.1016/s0006-2952(01)00716-x] [Cited by in Crossref: 37] [Cited by in F6Publishing: 9] [Article Influence: 1.9] [Reference Citation Analysis]
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40 Mankowski DC, Lawton MP, Ekins S. Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates. Xenobiotica 2008;30:745-54. [DOI: 10.1080/00498250050119817] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
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42 Zhu HJ, Appel DI, Jiang Y, Markowitz JS. Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver. Drug Metab Dispos 2009;37:1819-25. [PMID: 19487248 DOI: 10.1124/dmd.109.028209] [Cited by in Crossref: 73] [Cited by in F6Publishing: 58] [Article Influence: 6.1] [Reference Citation Analysis]
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45 Patel NN, Crincoli CM, Kennedy EL, Frederick DM, Tchao R, Harvison PJ. Effect of gender, dose, and time on 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT)-induced hepatotoxicity in Fischer 344 rats. Xenobiotica 2008;38:435-49. [PMID: 18340566 DOI: 10.1080/00498250701830267] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
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49 Tejpar S, Yan P, Piessevaux H, Dietrich D, Brauchli P, Klingbiel D, Fiocca R, Delorenzi M, Bosman F, Roth AD. Clinical and pharmacogenetic determinants of 5-fluorouracyl/leucovorin/irinotecan toxicity: Results of the PETACC-3 trial. Eur J Cancer 2018;99:66-77. [PMID: 29909091 DOI: 10.1016/j.ejca.2018.05.009] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 2.7] [Reference Citation Analysis]
50 Lee J, Son J, Chae Y, Ahn SH, Lee W, Kim D, Chung S. Gender differences in the hepatic elimination and pharmacokinetics of lobeglitazone in rats: Gender Difference of Lobeglitazone in Rats. Biopharm Drug Dispos 2015;36:410-5. [DOI: 10.1002/bdd.1954] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
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52 Oshida K, Vasani N, Waxman DJ, Corton JC. Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event. PLoS One 2016;11:e0148308. [PMID: 26959975 DOI: 10.1371/journal.pone.0148308] [Cited by in Crossref: 33] [Cited by in F6Publishing: 27] [Article Influence: 6.6] [Reference Citation Analysis]
53 Ruiz-Laguna J, Abril N, García-Barrera T, Gómez-Ariza JL, López-Barea J, Pueyo C. Absolute transcript expression signatures of Cyp and Gst genes in Mus spretus to detect environmental contamination. Environ Sci Technol 2006;40:3646-52. [PMID: 16786706 DOI: 10.1021/es060056e] [Cited by in Crossref: 35] [Cited by in F6Publishing: 30] [Article Influence: 2.3] [Reference Citation Analysis]
54 Karanewsky DS, Arthur AJ, Liu H, Chi B, Markison S. Toxicological evaluation of a novel cooling compound: 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide. Toxicol Rep 2015;2:1291-309. [PMID: 28962472 DOI: 10.1016/j.toxrep.2015.09.001] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
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58 Pryde DC, Maw GN, Planken S, Platts MY, Sanderson V, Corless M, Stobie A, Barber CG, Russell R, Foster L, Barker L, Wayman C, Van Der Graaf P, Stacey P, Morren D, Kohl C, Beaumont K, Coggon S, Tute M. Novel Selective Inhibitors of Neutral Endopeptidase for the Treatment of Female Sexual Arousal Disorder. Synthesis and Activity of Functionalized Glutaramides. J Med Chem 2006;49:4409-24. [DOI: 10.1021/jm060133g] [Cited by in Crossref: 29] [Cited by in F6Publishing: 17] [Article Influence: 1.9] [Reference Citation Analysis]
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