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For: Emmanouilidou E, Melachroinou K, Roumeliotis T, Garbis SD, Ntzouni M, Margaritis LH, Stefanis L, Vekrellis K. Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J Neurosci. 2010;30:6838-6851. [PMID: 20484626 DOI: 10.1523/jneurosci.5699-09.2010] [Cited by in Crossref: 660] [Cited by in F6Publishing: 455] [Article Influence: 55.0] [Reference Citation Analysis]
Number Citing Articles
1 Li XY, Yang W, Li X, Li XR, Li W, Song Q, Sun L, Lin F, Chen Z, Wang C, Yu S. Phosphorylated Alpha-Synuclein in Red Blood Cells as a Potential Diagnostic Biomarker for Multiple System Atrophy: A Pilot Study. Parkinsons Dis 2020;2020:8740419. [PMID: 32089817 DOI: 10.1155/2020/8740419] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
2 Yuyama K, Sun H, Sakai S, Mitsutake S, Okada M, Tahara H, Furukawa J, Fujitani N, Shinohara Y, Igarashi Y. Decreased amyloid-β pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice. J Biol Chem 2014;289:24488-98. [PMID: 25037226 DOI: 10.1074/jbc.M114.577213] [Cited by in Crossref: 149] [Cited by in F6Publishing: 100] [Article Influence: 18.6] [Reference Citation Analysis]
3 Brahic M, Bousset L, Bieri G, Melki R, Gitler AD. Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1. Acta Neuropathol 2016;131:539-48. [PMID: 26820848 DOI: 10.1007/s00401-016-1538-0] [Cited by in Crossref: 81] [Cited by in F6Publishing: 74] [Article Influence: 13.5] [Reference Citation Analysis]
4 Badawy SMM, Okada T, Kajimoto T, Hirase M, Matovelo SA, Nakamura S, Yoshida D, Ijuin T, Nakamura SI. Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G-protein signaling. J Biol Chem 2018;293:8208-16. [PMID: 29632069 DOI: 10.1074/jbc.RA118.001986] [Cited by in Crossref: 22] [Cited by in F6Publishing: 14] [Article Influence: 5.5] [Reference Citation Analysis]
5 Chung CG, Lee H, Lee SB. Mechanisms of protein toxicity in neurodegenerative diseases. Cell Mol Life Sci 2018;75:3159-80. [PMID: 29947927 DOI: 10.1007/s00018-018-2854-4] [Cited by in Crossref: 51] [Cited by in F6Publishing: 47] [Article Influence: 12.8] [Reference Citation Analysis]
6 Brück D, Wenning GK, Stefanova N, Fellner L. Glia and alpha-synuclein in neurodegeneration: A complex interaction. Neurobiol Dis 2016;85:262-74. [PMID: 25766679 DOI: 10.1016/j.nbd.2015.03.003] [Cited by in Crossref: 103] [Cited by in F6Publishing: 101] [Article Influence: 14.7] [Reference Citation Analysis]
7 Delenclos M, Trendafilova T, Mahesh D, Baine AM, Moussaud S, Yan IK, Patel T, McLean PJ. Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein. Front Neurosci 2017;11:172. [PMID: 28424577 DOI: 10.3389/fnins.2017.00172] [Cited by in Crossref: 48] [Cited by in F6Publishing: 47] [Article Influence: 9.6] [Reference Citation Analysis]
8 Borland H, Vilhardt F. Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds. Int J Mol Sci 2017;18:E227. [PMID: 28124989 DOI: 10.3390/ijms18010227] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 3.8] [Reference Citation Analysis]
9 Huo L, Du X, Li X, Liu S, Xu Y. The Emerging Role of Neural Cell-Derived Exosomes in Intercellular Communication in Health and Neurodegenerative Diseases. Front Neurosci 2021;15:738442. [PMID: 34531720 DOI: 10.3389/fnins.2021.738442] [Reference Citation Analysis]
10 Banigan MG, Kao PF, Kozubek JA, Winslow AR, Medina J, Costa J, Schmitt A, Schneider A, Cabral H, Cagsal-Getkin O, Vanderburg CR, Delalle I. Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. PLoS One 2013;8:e48814. [PMID: 23382797 DOI: 10.1371/journal.pone.0048814] [Cited by in Crossref: 134] [Cited by in F6Publishing: 128] [Article Influence: 14.9] [Reference Citation Analysis]
11 Castonguay AM, Gravel C, Lévesque M. Treating Parkinson's Disease with Antibodies: Previous Studies and Future Directions. J Parkinsons Dis 2021;11:71-92. [PMID: 33104039 DOI: 10.3233/JPD-202221] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
12 van der Vos KE, Balaj L, Skog J, Breakefield XO. Brain tumor microvesicles: insights into intercellular communication in the nervous system. Cell Mol Neurobiol 2011;31:949-59. [PMID: 21553248 DOI: 10.1007/s10571-011-9697-y] [Cited by in Crossref: 69] [Cited by in F6Publishing: 69] [Article Influence: 6.3] [Reference Citation Analysis]
13 Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, Bergmann A, Rockenstein E, Adame A, Marxreiter F, Mollenhauer B, Galasko D, Buzás EI, Schlötzer-Schrehardt U, Marcus K, Xiang W, Lie DC, Vekrellis K, Masliah E, Winkler J, Klucken J. Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype. Autophagy 2018;14:98-119. [PMID: 29198173 DOI: 10.1080/15548627.2017.1395992] [Cited by in Crossref: 100] [Cited by in F6Publishing: 93] [Article Influence: 25.0] [Reference Citation Analysis]
14 Abdulrahman BA, Abdelaziz DH, Schatzl HM. Autophagy regulates exosomal release of prions in neuronal cells. J Biol Chem 2018;293:8956-68. [PMID: 29700113 DOI: 10.1074/jbc.RA117.000713] [Cited by in Crossref: 55] [Cited by in F6Publishing: 39] [Article Influence: 13.8] [Reference Citation Analysis]
15 Henderson MX, Henrich MT, Geibl FF, Oertel WH, Brundin P, Surmeier DJ. The roles of connectivity and neuronal phenotype in determining the pattern of α-synuclein pathology in Parkinson's disease. Neurobiology of Disease 2022. [DOI: 10.1016/j.nbd.2022.105687] [Reference Citation Analysis]
16 Spencer B, Kim C, Gonzalez T, Bisquertt A, Patrick C, Rockenstein E, Adame A, Lee SJ, Desplats P, Masliah E. α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease. Hum Mol Genet 2016;25:1100-15. [PMID: 26740557 DOI: 10.1093/hmg/ddv633] [Cited by in Crossref: 34] [Cited by in F6Publishing: 34] [Article Influence: 5.7] [Reference Citation Analysis]
17 Ageta H, Tsuchida K. Post-translational modification and protein sorting to small extracellular vesicles including exosomes by ubiquitin and UBLs. Cell Mol Life Sci 2019;76:4829-48. [PMID: 31363817 DOI: 10.1007/s00018-019-03246-7] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 5.7] [Reference Citation Analysis]
18 Rey NL, Petit GH, Bousset L, Melki R, Brundin P. Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice. Acta Neuropathol 2013;126:555-73. [PMID: 23925565 DOI: 10.1007/s00401-013-1160-3] [Cited by in Crossref: 171] [Cited by in F6Publishing: 161] [Article Influence: 19.0] [Reference Citation Analysis]
19 Kim C, Ho DH, Suk JE, You S, Michael S, Kang J, Joong Lee S, Masliah E, Hwang D, Lee HJ, Lee SJ. Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia. Nat Commun 2013;4:1562. [PMID: 23463005 DOI: 10.1038/ncomms2534] [Cited by in Crossref: 399] [Cited by in F6Publishing: 398] [Article Influence: 44.3] [Reference Citation Analysis]
20 Garden GA, La Spada AR. Intercellular (mis)communication in neurodegenerative disease. Neuron 2012;73:886-901. [PMID: 22405200 DOI: 10.1016/j.neuron.2012.02.017] [Cited by in Crossref: 84] [Cited by in F6Publishing: 80] [Article Influence: 8.4] [Reference Citation Analysis]
21 Kalani A, Tyagi A, Tyagi N. Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics. Mol Neurobiol. 2014;49:590-600. [PMID: 23999871 DOI: 10.1007/s12035-013-8544-1] [Cited by in Crossref: 186] [Cited by in F6Publishing: 183] [Article Influence: 20.7] [Reference Citation Analysis]
22 Braccioli L, van Velthoven C, Heijnen CJ. Exosomes: a new weapon to treat the central nervous system. Mol Neurobiol 2014;49:113-9. [PMID: 23857502 DOI: 10.1007/s12035-013-8504-9] [Cited by in Crossref: 37] [Cited by in F6Publishing: 33] [Article Influence: 4.1] [Reference Citation Analysis]
23 Hunn BH, Cragg SJ, Bolam JP, Spillantini MG, Wade-Martins R. Impaired intracellular trafficking defines early Parkinson's disease. Trends Neurosci 2015;38:178-88. [PMID: 25639775 DOI: 10.1016/j.tins.2014.12.009] [Cited by in Crossref: 112] [Cited by in F6Publishing: 103] [Article Influence: 16.0] [Reference Citation Analysis]
24 George S, Rey NL, Reichenbach N, Steiner JA, Brundin P. α-Synuclein: the long distance runner. Brain Pathol 2013;23:350-7. [PMID: 23587141 DOI: 10.1111/bpa.12046] [Cited by in Crossref: 80] [Cited by in F6Publishing: 71] [Article Influence: 8.9] [Reference Citation Analysis]
25 Ouerdane Y, Hassaballah MY, Nagah A, Ibrahim TM, Mohamed HAH, El-baz A, Attia MS. Exosomes in Parkinson: Revisiting Their Pathologic Role and Potential Applications. Pharmaceuticals 2022;15:76. [DOI: 10.3390/ph15010076] [Reference Citation Analysis]
26 Davis AA, Leyns CEG, Holtzman DM. Intercellular Spread of Protein Aggregates in Neurodegenerative Disease. Annu Rev Cell Dev Biol 2018;34:545-68. [PMID: 30044648 DOI: 10.1146/annurev-cellbio-100617-062636] [Cited by in Crossref: 44] [Cited by in F6Publishing: 41] [Article Influence: 11.0] [Reference Citation Analysis]
27 Zhou W, Barkow JC, Freed CR. Running wheel exercise reduces α-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease. PLoS One 2017;12:e0190160. [PMID: 29272304 DOI: 10.1371/journal.pone.0190160] [Cited by in Crossref: 34] [Cited by in F6Publishing: 32] [Article Influence: 6.8] [Reference Citation Analysis]
28 von Einem B, Eschbach J, Kiechle M, Wahler A, Thal DR, McLean PJ, Weishaupt JH, Ludolph AC, von Arnim CAF, Danzer KM. The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion. Aging (Albany NY) 2017;9:1677-97. [PMID: 28722658 DOI: 10.18632/aging.101261] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.5] [Reference Citation Analysis]
29 Chung CC, Chan L, Chen JH, Hung YC, Hong CT. Plasma Extracellular Vesicle α-Synuclein Level in Patients with Parkinson's Disease. Biomolecules 2021;11:744. [PMID: 34067663 DOI: 10.3390/biom11050744] [Reference Citation Analysis]
30 Dudzik CG, Walter ED, Abrams BS, Jurica MS, Millhauser GL. Coordination of copper to the membrane-bound form of α-synuclein. Biochemistry 2013;52:53-60. [PMID: 23252394 DOI: 10.1021/bi301475q] [Cited by in Crossref: 30] [Cited by in F6Publishing: 26] [Article Influence: 3.0] [Reference Citation Analysis]
31 Peng C, Trojanowski JQ, Lee VM. Protein transmission in neurodegenerative disease. Nat Rev Neurol 2020;16:199-212. [PMID: 32203399 DOI: 10.1038/s41582-020-0333-7] [Cited by in Crossref: 99] [Cited by in F6Publishing: 88] [Article Influence: 49.5] [Reference Citation Analysis]
32 Guiney SJ, Adlard PA, Lei P, Mawal CH, Bush AI, Finkelstein DI, Ayton S. Fibrillar α-synuclein toxicity depends on functional lysosomes. J Biol Chem 2020;295:17497-513. [PMID: 33453994 DOI: 10.1074/jbc.RA120.013428] [Cited by in Crossref: 7] [Cited by in F6Publishing: 3] [Article Influence: 7.0] [Reference Citation Analysis]
33 Street JM, Barran PE, Mackay CL, Weidt S, Balmforth C, Walsh TS, Chalmers RT, Webb DJ, Dear JW. Identification and proteomic profiling of exosomes in human cerebrospinal fluid. J Transl Med. 2012;10:5. [PMID: 22221959 DOI: 10.1186/1479-5876-10-5] [Cited by in Crossref: 268] [Cited by in F6Publishing: 267] [Article Influence: 26.8] [Reference Citation Analysis]
34 Choi SI, Kim BY, Dadakhujaev S, Oh JY, Kim TI, Kim JY, Kim EK. Impaired autophagy and delayed autophagic clearance of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy type 2. Autophagy 2012;8:1782-97. [PMID: 22995918 DOI: 10.4161/auto.22067] [Cited by in Crossref: 37] [Cited by in F6Publishing: 36] [Article Influence: 3.7] [Reference Citation Analysis]
35 Iraci N, Leonardi T, Gessler F, Vega B, Pluchino S. Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles. Int J Mol Sci 2016;17:171. [PMID: 26861302 DOI: 10.3390/ijms17020171] [Cited by in Crossref: 140] [Cited by in F6Publishing: 130] [Article Influence: 23.3] [Reference Citation Analysis]
36 Caranci G, Piscopo P, Rivabene R, Traficante A, Riozzi B, Castellano AE, Ruggieri S, Vanacore N, Confaloni A. Gender differences in Parkinson's disease: focus on plasma α-synuclein. J Neural Transm (Vienna) 2013;120:1209-15. [PMID: 23328951 DOI: 10.1007/s00702-013-0972-6] [Cited by in Crossref: 26] [Cited by in F6Publishing: 28] [Article Influence: 2.9] [Reference Citation Analysis]
37 Chivet M, Javalet C, Laulagnier K, Blot B, Hemming FJ, Sadoul R. Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons. J Extracell Vesicles 2014;3:24722. [PMID: 25398455 DOI: 10.3402/jev.v3.24722] [Cited by in Crossref: 123] [Cited by in F6Publishing: 130] [Article Influence: 15.4] [Reference Citation Analysis]
38 Vafiadaki E, Arvanitis DA, Papalouka V, Terzis G, Roumeliotis TI, Spengos K, Garbis SD, Manta P, Kranias EG, Sanoudou D. Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiation. FEBS J 2014;281:3261-79. [PMID: 24860983 DOI: 10.1111/febs.12859] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 2.4] [Reference Citation Analysis]
39 Scheiblich H, Bousset L, Schwartz S, Griep A, Latz E, Melki R, Heneka MT. Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies. J Immunol 2021;207:2143-54. [PMID: 34507948 DOI: 10.4049/jimmunol.2100035] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
40 Desdín-micó G, Mittelbrunn M. Role of exosomes in the protection of cellular homeostasis. Cell Adhesion & Migration 2017;11:127-34. [DOI: 10.1080/19336918.2016.1251000] [Cited by in Crossref: 70] [Cited by in F6Publishing: 67] [Article Influence: 11.7] [Reference Citation Analysis]
41 Li H, Li C, Zhou Y, Luo C, Ou J, Li J, Mo Z. Expression of microRNAs in the serum exosomes of methamphetamine-dependent rats vs. ketamine-dependent rats. Exp Ther Med 2018;15:3369-75. [PMID: 29545857 DOI: 10.3892/etm.2018.5814] [Cited by in Crossref: 2] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
42 Scesa G, Moyano AL, Bongarzone ER, Givogri MI. Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles. J Neurosci Res 2016;94:1333-40. [PMID: 27638615 DOI: 10.1002/jnr.23798] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 1.6] [Reference Citation Analysis]
43 Lai JJ, Chau ZL, Chen SY, Hill JJ, Korpany KV, Liang NW, Lin LH, Lin YH, Liu JK, Liu YC, Lunde R, Shen WT. Exosome Processing and Characterization Approaches for Research and Technology Development. Adv Sci (Weinh) 2022;:e2103222. [PMID: 35332686 DOI: 10.1002/advs.202103222] [Reference Citation Analysis]
44 Shi M, Sheng L, Stewart T, Zabetian CP, Zhang J. New windows into the brain: Central nervous system-derived extracellular vesicles in blood. Prog Neurobiol 2019;175:96-106. [PMID: 30685501 DOI: 10.1016/j.pneurobio.2019.01.005] [Cited by in Crossref: 58] [Cited by in F6Publishing: 57] [Article Influence: 19.3] [Reference Citation Analysis]
45 Hooper C, Sainz-Fuertes R, Lynham S, Hye A, Killick R, Warley A, Bolondi C, Pocock J, Lovestone S. Wnt3a induces exosome secretion from primary cultured rat microglia. BMC Neurosci 2012;13:144. [PMID: 23173708 DOI: 10.1186/1471-2202-13-144] [Cited by in Crossref: 61] [Cited by in F6Publishing: 61] [Article Influence: 6.1] [Reference Citation Analysis]
46 Estes RE, Lin B, Khera A, Davis MY. Lipid Metabolism Influence on Neurodegenerative Disease Progression: Is the Vehicle as Important as the Cargo? Front Mol Neurosci 2021;14:788695. [PMID: 34987360 DOI: 10.3389/fnmol.2021.788695] [Reference Citation Analysis]
47 Yahi N, Di Scala C, Chahinian H, Fantini J. Innovative treatment targeting gangliosides aimed at blocking the formation of neurotoxic α-synuclein oligomers in Parkinson's disease. Glycoconj J 2021. [PMID: 34328594 DOI: 10.1007/s10719-021-10012-0] [Reference Citation Analysis]
48 Wilkaniec A, Cieślik M, Murawska E, Babiec L, Gąssowska-Dobrowolska M, Pałasz E, Jęśko H, Adamczyk A. P2X7 Receptor is Involved in Mitochondrial Dysfunction Induced by Extracellular Alpha Synuclein in Neuroblastoma SH-SY5Y Cells. Int J Mol Sci 2020;21:E3959. [PMID: 32486485 DOI: 10.3390/ijms21113959] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
49 Poehler AM, Xiang W, Spitzer P, May VE, Meixner H, Rockenstein E, Chutna O, Outeiro TF, Winkler J, Masliah E, Klucken J. Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment. Autophagy 2014;10:2171-92. [PMID: 25484190 DOI: 10.4161/auto.36436] [Cited by in Crossref: 131] [Cited by in F6Publishing: 121] [Article Influence: 18.7] [Reference Citation Analysis]
50 Shan FY, Fung KM, Zieneldien T, Kim J, Cao C, Huang JH. Examining the Toxicity of α-Synuclein in Neurodegenerative Disorders. Life (Basel) 2021;11:1126. [PMID: 34833002 DOI: 10.3390/life11111126] [Reference Citation Analysis]
51 Akers JC, Ramakrishnan V, Nolan JP, Duggan E, Fu CC, Hochberg FH, Chen CC, Carter BS. Comparative Analysis of Technologies for Quantifying Extracellular Vesicles (EVs) in Clinical Cerebrospinal Fluids (CSF). PLoS One 2016;11:e0149866. [PMID: 26901428 DOI: 10.1371/journal.pone.0149866] [Cited by in Crossref: 64] [Cited by in F6Publishing: 55] [Article Influence: 10.7] [Reference Citation Analysis]
52 Retana Moreira L, Rodríguez Serrano F, Osuna A. Extracellular vesicles of Trypanosoma cruzi tissue-culture cell-derived trypomastigotes: Induction of physiological changes in non-parasitized culture cells. PLoS Negl Trop Dis 2019;13:e0007163. [PMID: 30789912 DOI: 10.1371/journal.pntd.0007163] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 3.7] [Reference Citation Analysis]
53 Maurya SK, Bhattacharya N, Mishra S, Bhattacharya A, Banerjee P, Senapati S, Mishra R. Microglia Specific Drug Targeting Using Natural Products for the Regulation of Redox Imbalance in Neurodegeneration. Front Pharmacol 2021;12:654489. [PMID: 33927630 DOI: 10.3389/fphar.2021.654489] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
54 Karch CM, Jeng AT, Goate AM. Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies. J Biol Chem 2012;287:42751-62. [PMID: 23105105 DOI: 10.1074/jbc.M112.380642] [Cited by in Crossref: 110] [Cited by in F6Publishing: 67] [Article Influence: 11.0] [Reference Citation Analysis]
55 Picca A, Guerra F, Calvani R, Romano R, Coelho-Júnior HJ, Bucci C, Marzetti E. Mitochondrial Dysfunction, Protein Misfolding and Neuroinflammation in Parkinson's Disease: Roads to Biomarker Discovery. Biomolecules 2021;11:1508. [PMID: 34680141 DOI: 10.3390/biom11101508] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
56 Hornung S, Dutta S, Bitan G. CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges. Front Mol Neurosci 2020;13:38. [PMID: 32265650 DOI: 10.3389/fnmol.2020.00038] [Cited by in Crossref: 40] [Cited by in F6Publishing: 39] [Article Influence: 20.0] [Reference Citation Analysis]
57 Ulamec SM, Brockwell DJ, Radford SE. Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins. Front Neurosci 2020;14:611285. [PMID: 33335475 DOI: 10.3389/fnins.2020.611285] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 2.5] [Reference Citation Analysis]
58 Campbell LA, Mocchetti I. Extracellular Vesicles and HIV-Associated Neurocognitive Disorders: Implications in Neuropathogenesis and Disease Diagnosis. Neurotox Res 2021. [PMID: 34618322 DOI: 10.1007/s12640-021-00425-y] [Reference Citation Analysis]
59 Oliveira LMA, Gasser T, Edwards R, Zweckstetter M, Melki R, Stefanis L, Lashuel HA, Sulzer D, Vekrellis K, Halliday GM, Tomlinson JJ, Schlossmacher M, Jensen PH, Schulze-Hentrich J, Riess O, Hirst WD, El-Agnaf O, Mollenhauer B, Lansbury P, Outeiro TF. Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease. NPJ Parkinsons Dis 2021;7:65. [PMID: 34312398 DOI: 10.1038/s41531-021-00203-9] [Reference Citation Analysis]
60 Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, Binder LI, Mandelkow EM, Diamond MI, Lee VM, Holtzman DM. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J Neurosci 2011;31:13110-7. [PMID: 21917794 DOI: 10.1523/JNEUROSCI.2569-11.2011] [Cited by in Crossref: 217] [Cited by in F6Publishing: 152] [Article Influence: 19.7] [Reference Citation Analysis]
61 Gleixner AM, Hutchison DF, Sannino S, Bhatia TN, Leak LC, Flaherty PT, Wipf P, Brodsky JL, Leak RK. N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione. Mol Pharmacol 2017;92:564-75. [PMID: 28830914 DOI: 10.1124/mol.117.109926] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 3.8] [Reference Citation Analysis]
62 Jiang L, Dong H, Cao H, Ji X, Luan S, Liu J. Exosomes in Pathogenesis, Diagnosis, and Treatment of Alzheimer's Disease. Med Sci Monit 2019;25:3329-35. [PMID: 31056537 DOI: 10.12659/MSM.914027] [Cited by in Crossref: 20] [Cited by in F6Publishing: 13] [Article Influence: 6.7] [Reference Citation Analysis]
63 Zampese E, Surmeier DJ. Calcium, Bioenergetics, and Parkinson's Disease. Cells 2020;9:E2045. [PMID: 32911641 DOI: 10.3390/cells9092045] [Cited by in Crossref: 15] [Cited by in F6Publishing: 10] [Article Influence: 7.5] [Reference Citation Analysis]
64 Dexter E, Kong Q. Neuroprotective effect and potential of cellular prion protein and its cleavage products for treatment of neurodegenerative disorders part II: strategies for therapeutics development. Expert Rev Neurother 2021;21:983-91. [PMID: 34470554 DOI: 10.1080/14737175.2021.1965882] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
65 Payandeh Z, Pirpour Tazehkand A, Azargoonjahromi A, Almasi F, Alagheband Bahrami A. The Role of Cell Organelles in Rheumatoid Arthritis with Focus on Exosomes. Biol Proced Online 2021;23:20. [PMID: 34736402 DOI: 10.1186/s12575-021-00158-4] [Reference Citation Analysis]
66 Ramirez AE, Fernández-Pérez EJ, Olivos N, Burgos CF, Boopathi S, Armijo-Weingart L, Pacheco CR, González W, Aguayo LG. The Stimulatory Effects of Intracellular α-Synuclein on Synaptic Transmission Are Attenuated by 2-Octahydroisoquinolin-2(1H)-ylethanamine. Int J Mol Sci 2021;22:13253. [PMID: 34948050 DOI: 10.3390/ijms222413253] [Reference Citation Analysis]
67 Falsone A, Falsone SF. Legal but lethal: functional protein aggregation at the verge of toxicity. Front Cell Neurosci 2015;9:45. [PMID: 25741240 DOI: 10.3389/fncel.2015.00045] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 2.1] [Reference Citation Analysis]
68 Foulds PG, Yokota O, Thurston A, Davidson Y, Ahmed Z, Holton J, Thompson JC, Akiyama H, Arai T, Hasegawa M, Gerhard A, Allsop D, Mann DM. Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies. Neurobiol Dis 2012;45:188-95. [PMID: 21856424 DOI: 10.1016/j.nbd.2011.08.003] [Cited by in Crossref: 61] [Cited by in F6Publishing: 57] [Article Influence: 5.5] [Reference Citation Analysis]
69 Hanspal MA, Dobson CM, Yerbury JJ, Kumita JR. The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis. Biochim Biophys Acta Mol Basis Dis 2017;1863:2762-71. [PMID: 28711596 DOI: 10.1016/j.bbadis.2017.07.007] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 2.6] [Reference Citation Analysis]
70 Li HC, Lin YB, Li C, Luo CH, Zhou YT, Ou JY, Li J, Mo ZX. Expression of miRNAs in Serum Exosomes versus Hippocampus in Methamphetamine-Induced Rats and Intervention of Rhynchophylline. Evid Based Complement Alternat Med 2018;2018:8025062. [PMID: 29636786 DOI: 10.1155/2018/8025062] [Cited by in Crossref: 2] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
71 Sauerbeck AD, Goldstein EZ, Alfredo AN, Norenberg M, Marcillo A, McTigue DM. Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss. Sci Rep 2021;11:11720. [PMID: 34083630 DOI: 10.1038/s41598-021-91116-3] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
72 Brás IC, Outeiro TF. Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies. Cells 2021;10:375. [PMID: 33673034 DOI: 10.3390/cells10020375] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
73 Roberts HL, Brown DR. Seeking a mechanism for the toxicity of oligomeric α-synuclein. Biomolecules 2015;5:282-305. [PMID: 25816357 DOI: 10.3390/biom5020282] [Cited by in Crossref: 122] [Cited by in F6Publishing: 114] [Article Influence: 17.4] [Reference Citation Analysis]
74 He J, Ren W, Wang W, Han W, Jiang L, Zhang D, Guo M. Exosomal targeting and its potential clinical application. Drug Deliv Transl Res 2021. [PMID: 34973131 DOI: 10.1007/s13346-021-01087-1] [Reference Citation Analysis]
75 Ugras S, Daniels MJ, Fazelinia H, Gould NS, Yocum AK, Luk KC, Luna E, Ding H, McKennan C, Seeholzer S, Martinez D, Evans P, Brown D, Duda JE, Ischiropoulos H. Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders. EBioMedicine 2018;31:307-19. [PMID: 29759483 DOI: 10.1016/j.ebiom.2018.05.007] [Cited by in F6Publishing: 20] [Reference Citation Analysis]
76 Masuda-Suzukake M, Nonaka T, Hosokawa M, Oikawa T, Arai T, Akiyama H, Mann DM, Hasegawa M. Prion-like spreading of pathological α-synuclein in brain. Brain. 2013;136:1128-1138. [PMID: 23466394 DOI: 10.1093/brain/awt037] [Cited by in Crossref: 485] [Cited by in F6Publishing: 463] [Article Influence: 53.9] [Reference Citation Analysis]
77 Guo BB, Bellingham SA, Hill AF. The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes. J Biol Chem. 2015;290:3455-3467. [PMID: 25505180 DOI: 10.1074/jbc.m114.605253] [Cited by in Crossref: 120] [Cited by in F6Publishing: 83] [Article Influence: 15.0] [Reference Citation Analysis]
78 Sato H, Kato T, Arawaka S. Potential of Cellular and Animal Models Based on a Prion-Like Propagation of α-Synuclein for Assessing Antiparkinson Agents. Mol Neurobiol 2015;52:226-35. [PMID: 25143237 DOI: 10.1007/s12035-014-8858-7] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
79 Zeidan B, Jackson TR, Larkin SE, Cutress RI, Coulton GR, Ashton-Key M, Murray N, Packham G, Gorgoulis V, Garbis SD, Townsend PA. Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target. Oncotarget 2015;6:21421-7. [PMID: 26093083 DOI: 10.18632/oncotarget.4070] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
80 Fellner L, Buchinger E, Brueck D, Irschick R, Wenning GK, Stefanova N. Limited effects of dysfunctional macroautophagy on the accumulation of extracellularly derived α-synuclein in oligodendroglia: implications for MSA pathogenesis. BMC Neurosci 2018;19:32. [PMID: 29783943 DOI: 10.1186/s12868-018-0431-2] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
81 Miller SJ, Campbell CE, Jimenez-corea HA, Wu G, Logan R. Neuroglial Senescence, α-Synucleinopathy, and the Therapeutic Potential of Senolytics in Parkinson’s Disease. Front Neurosci 2022;16:824191. [DOI: 10.3389/fnins.2022.824191] [Reference Citation Analysis]
82 Hinzman CP, Baulch JE, Mehta KY, Girgis M, Bansal S, Gill K, Li Y, Limoli CL, Cheema AK. Plasma-derived extracellular vesicles yield predictive markers of cranial irradiation exposure in mice. Sci Rep 2019;9:9460. [PMID: 31263197 DOI: 10.1038/s41598-019-45970-x] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 3.7] [Reference Citation Analysis]
83 Agnati LF, Fuxe K. Extracellular-vesicle type of volume transmission and tunnelling-nanotube type of wiring transmission add a new dimension to brain neuro-glial networks. Philos Trans R Soc Lond B Biol Sci 2014;369:20130505. [PMID: 25135966 DOI: 10.1098/rstb.2013.0505] [Cited by in Crossref: 41] [Cited by in F6Publishing: 37] [Article Influence: 5.9] [Reference Citation Analysis]
84 Doyle LM, Wang MZ. Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis. Cells. 2019;8. [PMID: 31311206 DOI: 10.3390/cells8070727] [Cited by in Crossref: 353] [Cited by in F6Publishing: 363] [Article Influence: 117.7] [Reference Citation Analysis]
85 Namme JN, Bepari AK, Takebayashi H. Cofilin Signaling in the CNS Physiology and Neurodegeneration. Int J Mol Sci 2021;22:10727. [PMID: 34639067 DOI: 10.3390/ijms221910727] [Reference Citation Analysis]
86 Chu Y, Kordower JH. The prion hypothesis of Parkinson's disease. Curr Neurol Neurosci Rep 2015;15:28. [PMID: 25868519 DOI: 10.1007/s11910-015-0549-x] [Cited by in Crossref: 43] [Cited by in F6Publishing: 36] [Article Influence: 6.1] [Reference Citation Analysis]
87 Han C, Xiong N, Guo X, Huang J, Ma K, Liu L, Xia Y, Shen Y, Li J, Jiang H, Wang L, Guo S, Xu X, Zhang G, Liu J, Cao X, Zhang Z, Lin Z, Wang T. Exosomes from patients with Parkinson's disease are pathological in mice. J Mol Med (Berl) 2019;97:1329-44. [PMID: 31302715 DOI: 10.1007/s00109-019-01810-z] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 6.7] [Reference Citation Analysis]
88 Shin EJ, Jeong JH, Hwang Y, Sharma N, Dang DK, Nguyen BT, Nah SY, Jang CG, Bing G, Nabeshima T, Kim HC. Methamphetamine-induced dopaminergic neurotoxicity as a model of Parkinson's disease. Arch Pharm Res 2021;44:668-88. [PMID: 34286473 DOI: 10.1007/s12272-021-01341-7] [Reference Citation Analysis]
89 Cheng J, Lu Q, Song L, Ho MS. α-Synuclein Trafficking in Parkinson's Disease: Insights From Fly and Mouse Models. ASN Neuro 2018;10:1759091418812587. [PMID: 30482039 DOI: 10.1177/1759091418812587] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 3.0] [Reference Citation Analysis]
90 Parres-Gold J, Chieng A, Wong Su S, Wang Y. Real-Time Characterization of Cell Membrane Disruption by α-Synuclein Oligomers in Live SH-SY5Y Neuroblastoma Cells. ACS Chem Neurosci 2020;11:2528-34. [PMID: 32786327 DOI: 10.1021/acschemneuro.0c00309] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 2.5] [Reference Citation Analysis]
91 Surmeier DJ, Sulzer D. The pathology roadmap in Parkinson disease. Prion 2013;7:85-91. [PMID: 23324593 DOI: 10.4161/pri.23582] [Cited by in Crossref: 44] [Cited by in F6Publishing: 40] [Article Influence: 4.9] [Reference Citation Analysis]
92 Van Den Berge N, Ulusoy A. Animal models of brain-first and body-first Parkinson's disease. Neurobiology of Disease 2022;163:105599. [DOI: 10.1016/j.nbd.2021.105599] [Reference Citation Analysis]
93 Chen ZJ, Liang CY, Yang LQ, Ren SM, Xia YM, Cui L, Li XF, Gao BL. Association of Parkinson's Disease With Microbes and Microbiological Therapy. Front Cell Infect Microbiol 2021;11:619354. [PMID: 33763383 DOI: 10.3389/fcimb.2021.619354] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
94 Exner N, Lutz AK, Haass C, Winklhofer KF. Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences. EMBO J 2012;31:3038-62. [PMID: 22735187 DOI: 10.1038/emboj.2012.170] [Cited by in Crossref: 363] [Cited by in F6Publishing: 335] [Article Influence: 36.3] [Reference Citation Analysis]
95 Zhao ZH, Chen ZT, Zhou RL, Zhang X, Ye QY, Wang YZ. Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson's Disease. Front Aging Neurosci 2018;10:438. [PMID: 30692923 DOI: 10.3389/fnagi.2018.00438] [Cited by in Crossref: 51] [Cited by in F6Publishing: 48] [Article Influence: 17.0] [Reference Citation Analysis]
96 Choi JY, Kim S, Kwak HB, Park DH, Park JH, Ryu JS, Park CS, Kang JH. Extracellular Vesicles as a Source of Urological Biomarkers: Lessons Learned From Advances and Challenges in Clinical Applications to Major Diseases. Int Neurourol J. 2017;21:83-96. [PMID: 28673066 DOI: 10.5213/inj.1734961.458] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.6] [Reference Citation Analysis]
97 Twohig D, Rodriguez-Vieitez E, Sando SB, Berge G, Lauridsen C, Møller I, Grøntvedt GR, Bråthen G, Patra K, Bu G, Benzinger TLS, Karch CM, Fagan A, Morris JC, Bateman RJ, Nordberg A, White LR, Nielsen HM; Dominantly Inherited Alzheimer Network (DIAN). The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease. Acta Neuropathol Commun 2018;6:130. [PMID: 30477568 DOI: 10.1186/s40478-018-0624-z] [Cited by in Crossref: 24] [Cited by in F6Publishing: 21] [Article Influence: 6.0] [Reference Citation Analysis]
98 Jackson WS. Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein. Dis Model Mech 2014;7:21-9. [PMID: 24396151 DOI: 10.1242/dmm.012146] [Cited by in Crossref: 52] [Cited by in F6Publishing: 45] [Article Influence: 6.5] [Reference Citation Analysis]
99 Jadli AS, Ballasy N, Edalat P, Patel VB. Inside(sight) of tiny communicator: exosome biogenesis, secretion, and uptake. Mol Cell Biochem 2020;467:77-94. [PMID: 32088833 DOI: 10.1007/s11010-020-03703-z] [Cited by in Crossref: 35] [Cited by in F6Publishing: 36] [Article Influence: 17.5] [Reference Citation Analysis]
100 Leggio L, Paternò G, Vivarelli S, Falzone GG, Giachino C, Marchetti B, Iraci N. Extracellular Vesicles as Novel Diagnostic and Prognostic Biomarkers for Parkinson's Disease. Aging Dis 2021;12:1494-515. [PMID: 34527424 DOI: 10.14336/AD.2021.0527] [Reference Citation Analysis]
101 Bellingham SA, Coleman BM, Hill AF. Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Nucleic Acids Res. 2012;40:10937-10949. [PMID: 22965126 DOI: 10.1093/nar/gks832] [Cited by in Crossref: 283] [Cited by in F6Publishing: 269] [Article Influence: 28.3] [Reference Citation Analysis]
102 Vandendriessche C, Bruggeman A, Van Cauwenberghe C, Vandenbroucke RE. Extracellular Vesicles in Alzheimer's and Parkinson's Disease: Small Entities with Large Consequences. Cells 2020;9:E2485. [PMID: 33203181 DOI: 10.3390/cells9112485] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 5.5] [Reference Citation Analysis]
103 Menéndez-González M, Padilla-Zambrano HS, Tomás-Zapico C, García BF. Clearing Extracellular Alpha-Synuclein from Cerebrospinal Fluid: A New Therapeutic Strategy in Parkinson's Disease. Brain Sci 2018;8:E52. [PMID: 29570693 DOI: 10.3390/brainsci8040052] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
104 Colla E, Coune P, Liu Y, Pletnikova O, Troncoso JC, Iwatsubo T, Schneider BL, Lee MK. Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo. J Neurosci 2012;32:3306-20. [PMID: 22399753 DOI: 10.1523/JNEUROSCI.5367-11.2012] [Cited by in Crossref: 232] [Cited by in F6Publishing: 147] [Article Influence: 23.2] [Reference Citation Analysis]
105 Graykowski DR, Wang YZ, Upadhyay A, Savas JN. The Dichotomous Role of Extracellular Vesicles in the Central Nervous System. iScience 2020;23:101456. [PMID: 32835924 DOI: 10.1016/j.isci.2020.101456] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 2.5] [Reference Citation Analysis]
106 Cai Q, Ganesan D. Regulation of neuronal autophagy and the implications in neurodegenerative diseases. Neurobiol Dis 2022;162:105582. [PMID: 34890791 DOI: 10.1016/j.nbd.2021.105582] [Reference Citation Analysis]
107 Gonçalves SA, Outeiro TF. Traffic jams and the complex role of α-Synuclein aggregation in Parkinson disease. Small GTPases 2017;8:78-84. [PMID: 27314512 DOI: 10.1080/21541248.2016.1199191] [Cited by in Crossref: 7] [Cited by in F6Publishing: 4] [Article Influence: 1.2] [Reference Citation Analysis]
108 Smethurst P, Franklin H, Clarke BE, Sidle K, Patani R. The role of astrocytes in prion-like mechanisms of neurodegeneration. Brain 2022:awab366. [PMID: 35265969 DOI: 10.1093/brain/awab366] [Reference Citation Analysis]
109 Tian C, Liu G, Gao L, Soltys D, Pan C, Stewart T, Shi M, Xie Z, Liu N, Feng T, Zhang J. Erythrocytic α-Synuclein as a potential biomarker for Parkinson's disease. Transl Neurodegener 2019;8:15. [PMID: 31123587 DOI: 10.1186/s40035-019-0155-y] [Cited by in Crossref: 23] [Cited by in F6Publishing: 23] [Article Influence: 7.7] [Reference Citation Analysis]
110 Barile L, Gherghiceanu M, Popescu LM, Moccetti T, Vassalli G. Ultrastructural evidence of exosome secretion by progenitor cells in adult mouse myocardium and adult human cardiospheres. J Biomed Biotechnol 2012;2012:354605. [PMID: 23226938 DOI: 10.1155/2012/354605] [Cited by in Crossref: 45] [Cited by in F6Publishing: 49] [Article Influence: 4.5] [Reference Citation Analysis]
111 Bellingham SA, Guo BB, Coleman BM, Hill AF. Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front Physiol 2012;3:124. [PMID: 22563321 DOI: 10.3389/fphys.2012.00124] [Cited by in Crossref: 229] [Cited by in F6Publishing: 238] [Article Influence: 22.9] [Reference Citation Analysis]
112 Mahul-Mellier AL, Vercruysse F, Maco B, Ait-Bouziad N, De Roo M, Muller D, Lashuel HA. Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death. Cell Death Differ 2015;22:2107-22. [PMID: 26138444 DOI: 10.1038/cdd.2015.79] [Cited by in Crossref: 61] [Cited by in F6Publishing: 54] [Article Influence: 8.7] [Reference Citation Analysis]
113 Liu S, Hossinger A, Hofmann JP, Denner P, Vorberg IM. Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles. mBio 2016;7:e00915-16. [PMID: 27406566 DOI: 10.1128/mBio.00915-16] [Cited by in Crossref: 26] [Cited by in F6Publishing: 18] [Article Influence: 4.3] [Reference Citation Analysis]
114 Menon S, Armstrong S, Hamzeh A, Visanji NP, Sardi SP, Tandon A. Alpha-Synuclein Targeting Therapeutics for Parkinson's Disease and Related Synucleinopathies. Front Neurol 2022;13:852003. [DOI: 10.3389/fneur.2022.852003] [Reference Citation Analysis]
115 Gosselin RD, Meylan P, Decosterd I. Extracellular microvesicles from astrocytes contain functional glutamate transporters: regulation by protein kinase C and cell activation. Front Cell Neurosci 2013;7:251. [PMID: 24368897 DOI: 10.3389/fncel.2013.00251] [Cited by in Crossref: 28] [Cited by in F6Publishing: 31] [Article Influence: 3.1] [Reference Citation Analysis]
116 Grad LI, Cashman NR. Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis. Prion. 2014;8:33-41. [PMID: 24394345 DOI: 10.4161/pri.27602] [Cited by in Crossref: 40] [Cited by in F6Publishing: 39] [Article Influence: 5.7] [Reference Citation Analysis]
117 Budnik V, Ruiz-Cañada C, Wendler F. Extracellular vesicles round off communication in the nervous system. Nat Rev Neurosci 2016;17:160-72. [PMID: 26891626 DOI: 10.1038/nrn.2015.29] [Cited by in Crossref: 291] [Cited by in F6Publishing: 288] [Article Influence: 48.5] [Reference Citation Analysis]
118 Jiang Z, de Messieres M, Lee JC. Membrane remodeling by α-synuclein and effects on amyloid formation. J Am Chem Soc 2013;135:15970-3. [PMID: 24099487 DOI: 10.1021/ja405993r] [Cited by in Crossref: 79] [Cited by in F6Publishing: 75] [Article Influence: 8.8] [Reference Citation Analysis]
119 Quadri Z, Elsherbini A, Bieberich E. Extracellular vesicles in pharmacology: Novel approaches in diagnostics and therapy. Pharmacol Res 2021;175:105980. [PMID: 34863822 DOI: 10.1016/j.phrs.2021.105980] [Reference Citation Analysis]
120 Song Z, Xu Y, Deng W, Zhang L, Zhu H, Yu P, Qu Y, Zhao W, Han Y, Qin C. Brain Derived Exosomes Are a Double-Edged Sword in Alzheimer's Disease. Front Mol Neurosci 2020;13:79. [PMID: 32547364 DOI: 10.3389/fnmol.2020.00079] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 7.5] [Reference Citation Analysis]
121 Santa-Maria I, Varghese M, Ksiezak-Reding H, Dzhun A, Wang J, Pasinetti GM. Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes. J Biol Chem 2012;287:20522-33. [PMID: 22496370 DOI: 10.1074/jbc.M111.323279] [Cited by in Crossref: 88] [Cited by in F6Publishing: 52] [Article Influence: 8.8] [Reference Citation Analysis]
122 Kim KS, Choi YR, Park JY, Lee JH, Kim DK, Lee SJ, Paik SR, Jou I, Park SM. Proteolytic cleavage of extracellular α-synuclein by plasmin: implications for Parkinson disease. J Biol Chem 2012;287:24862-72. [PMID: 22619171 DOI: 10.1074/jbc.M112.348128] [Cited by in Crossref: 45] [Cited by in F6Publishing: 22] [Article Influence: 4.5] [Reference Citation Analysis]
123 Kisos H, Pukaß K, Ben-Hur T, Richter-Landsberg C, Sharon R. Increased neuronal α-synuclein pathology associates with its accumulation in oligodendrocytes in mice modeling α-synucleinopathies. PLoS One 2012;7:e46817. [PMID: 23077527 DOI: 10.1371/journal.pone.0046817] [Cited by in Crossref: 66] [Cited by in F6Publishing: 64] [Article Influence: 6.6] [Reference Citation Analysis]
124 Twohig D, Nielsen HM. α-synuclein in the pathophysiology of Alzheimer's disease. Mol Neurodegener 2019;14:23. [PMID: 31186026 DOI: 10.1186/s13024-019-0320-x] [Cited by in Crossref: 54] [Cited by in F6Publishing: 49] [Article Influence: 18.0] [Reference Citation Analysis]
125 Sawada H, Oeda T, Umemura A, Tomita S, Kohsaka M, Park K, Yamamoto K, Sugiyama H. Baseline C-Reactive Protein Levels and Life Prognosis in Parkinson Disease. PLoS One 2015;10:e0134118. [PMID: 26218286 DOI: 10.1371/journal.pone.0134118] [Cited by in Crossref: 22] [Cited by in F6Publishing: 21] [Article Influence: 3.1] [Reference Citation Analysis]
126 Cremers CM, Knoefler D, Gates S, Martin N, Dahl JU, Lempart J, Xie L, Chapman MR, Galvan V, Southworth DR, Jakob U. Polyphosphate: A Conserved Modifier of Amyloidogenic Processes. Mol Cell 2016;63:768-80. [PMID: 27570072 DOI: 10.1016/j.molcel.2016.07.016] [Cited by in Crossref: 70] [Cited by in F6Publishing: 65] [Article Influence: 11.7] [Reference Citation Analysis]
127 Lim S, Chun Y, Lee JS, Lee SJ. Neuroinflammation in Synucleinopathies. Brain Pathol 2016;26:404-9. [PMID: 26940152 DOI: 10.1111/bpa.12371] [Cited by in Crossref: 32] [Cited by in F6Publishing: 35] [Article Influence: 8.0] [Reference Citation Analysis]
128 Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL. Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity. Cell Res 2017;27:882-97. [PMID: 28429770 DOI: 10.1038/cr.2017.62] [Cited by in Crossref: 114] [Cited by in F6Publishing: 123] [Article Influence: 22.8] [Reference Citation Analysis]
129 Ivanova MV, Chekanova EO, Belugin BV, Tutykhina IL, Dolzhikova IV, Zakroishchikova IV, Vasil’ev AV, Zakharova MN. Exosomal Transport and Progression of Neurodegeneration in Amyotrophic Lateral Sclerosis. Neurochem J 2019;13:229-39. [DOI: 10.1134/s1819712419030085] [Reference Citation Analysis]
130 Tsunemi T, Hamada K, Krainc D. ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein. J Neurosci 2014;34:15281-7. [PMID: 25392495 DOI: 10.1523/JNEUROSCI.1629-14.2014] [Cited by in Crossref: 107] [Cited by in F6Publishing: 70] [Article Influence: 15.3] [Reference Citation Analysis]
131 Prymaczok NC, Riek R, Gerez J. More than a Rumor Spreads in Parkinson's Disease. Front Hum Neurosci 2016;10:608. [PMID: 27994545 DOI: 10.3389/fnhum.2016.00608] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.3] [Reference Citation Analysis]
132 D'Anca M, Fenoglio C, Serpente M, Arosio B, Cesari M, Scarpini EA, Galimberti D. Exosome Determinants of Physiological Aging and Age-Related Neurodegenerative Diseases. Front Aging Neurosci 2019;11:232. [PMID: 31555123 DOI: 10.3389/fnagi.2019.00232] [Cited by in Crossref: 44] [Cited by in F6Publishing: 43] [Article Influence: 14.7] [Reference Citation Analysis]
133 Gartz M, Lin CW, Sussman MA, Lawlor MW, Strande JL. Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy. Dis Model Mech 2020;13:dmm045559. [PMID: 33188007 DOI: 10.1242/dmm.045559] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
134 Domingues R, Sant’anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF. Extracellular alpha-synuclein: Sensors, receptors, and responses. Neurobiology of Disease 2022. [DOI: 10.1016/j.nbd.2022.105696] [Reference Citation Analysis]
135 Polissidis A, Petropoulou-Vathi L, Nakos-Bimpos M, Rideout HJ. The Future of Targeted Gene-Based Treatment Strategies and Biomarkers in Parkinson's Disease. Biomolecules 2020;10:E912. [PMID: 32560161 DOI: 10.3390/biom10060912] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
136 Rodríguez-Losada N, de la Rosa J, Larriva M, Wendelbo R, Aguirre JA, Castresana JS, Ballaz SJ. Overexpression of alpha-synuclein promotes both cell proliferation and cell toxicity in human SH-SY5Y neuroblastoma cells. J Adv Res 2020;23:37-45. [PMID: 32071790 DOI: 10.1016/j.jare.2020.01.009] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 5.0] [Reference Citation Analysis]
137 Eitan E, Hutchison ER, Marosi K, Comotto J, Mustapic M, Nigam SM, Suire C, Maharana C, Jicha GA, Liu D, Machairaki V, Witwer KW, Kapogiannis D, Mattson MP. Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic and Ca2+-Handling Deficits in Alzheimer's Disease Models. NPJ Aging Mech Dis 2016;2:16019. [PMID: 27928512 DOI: 10.1038/npjamd.2016.19] [Cited by in Crossref: 61] [Cited by in F6Publishing: 57] [Article Influence: 10.2] [Reference Citation Analysis]
138 Ebrahimi-Fakhari D, Wahlster L, McLean PJ. Protein degradation pathways in Parkinson's disease: curse or blessing. Acta Neuropathol 2012;124:153-72. [PMID: 22744791 DOI: 10.1007/s00401-012-1004-6] [Cited by in Crossref: 158] [Cited by in F6Publishing: 142] [Article Influence: 15.8] [Reference Citation Analysis]
139 Guan Y, Zhao X, Liu F, Yan S, Wang Y, Du C, Cui X, Li R, Zhang CX. Pathogenic Mutations Differentially Regulate Cell-to-Cell Transmission of α-Synuclein. Front Cell Neurosci 2020;14:159. [PMID: 32595456 DOI: 10.3389/fncel.2020.00159] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 2.5] [Reference Citation Analysis]
140 Deng H, Xiu X, Jankovic J. Genetic convergence of Parkinson's disease and lysosomal storage disorders. Mol Neurobiol 2015;51:1554-68. [PMID: 25099932 DOI: 10.1007/s12035-014-8832-4] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 2.3] [Reference Citation Analysis]
141 Walker DG, Lue LF, Tang TM, Adler CH, Caviness JN, Sabbagh MN, Serrano GE, Sue LI, Beach TG. Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology. Neurobiol Aging 2017;54:175-86. [PMID: 28390825 DOI: 10.1016/j.neurobiolaging.2017.03.007] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 3.6] [Reference Citation Analysis]
142 Hansen C, Angot E, Bergström AL, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li JY, Brundin P. α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 2011;121:715-25. [PMID: 21245577 DOI: 10.1172/JCI43366] [Cited by in Crossref: 575] [Cited by in F6Publishing: 363] [Article Influence: 52.3] [Reference Citation Analysis]
143 Watson MD, Flynn JD, Lee JC. Raman spectral imaging of 13C2H15N-labeled α-synuclein amyloid fibrils in cells. Biophys Chem 2021;269:106528. [PMID: 33418468 DOI: 10.1016/j.bpc.2020.106528] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
144 Díaz-Hernández M, Gómez-Ramos A, Rubio A, Gómez-Villafuertes R, Naranjo JR, Miras-Portugal MT, Avila J. Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau. J Biol Chem 2010;285:32539-48. [PMID: 20634292 DOI: 10.1074/jbc.M110.145003] [Cited by in Crossref: 108] [Cited by in F6Publishing: 61] [Article Influence: 9.0] [Reference Citation Analysis]
145 Danzer KM, McLean PJ. Drug targets from genetics: α-synuclein. CNS Neurol Disord Drug Targets 2011;10:712-23. [PMID: 21838671 DOI: 10.2174/187152711797247867] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.9] [Reference Citation Analysis]
146 Fares MB, Jagannath S, Lashuel HA. Reverse engineering Lewy bodies: how far have we come and how far can we go? Nat Rev Neurosci 2021;22:111-31. [PMID: 33432241 DOI: 10.1038/s41583-020-00416-6] [Cited by in Crossref: 18] [Cited by in F6Publishing: 22] [Article Influence: 18.0] [Reference Citation Analysis]
147 Angot E, Steiner JA, Lema Tomé CM, Ekström P, Mattsson B, Björklund A, Brundin P. Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo. PLoS One. 2012;7:e39465. [PMID: 22737239 DOI: 10.1371/journal.pone.0039465] [Cited by in Crossref: 174] [Cited by in F6Publishing: 170] [Article Influence: 17.4] [Reference Citation Analysis]
148 Bátiz LF, Castro MA, Burgos PV, Velásquez ZD, Muñoz RI, Lafourcade CA, Troncoso-Escudero P, Wyneken U. Exosomes as Novel Regulators of Adult Neurogenic Niches. Front Cell Neurosci 2015;9:501. [PMID: 26834560 DOI: 10.3389/fncel.2015.00501] [Cited by in Crossref: 43] [Cited by in F6Publishing: 58] [Article Influence: 7.2] [Reference Citation Analysis]
149 Marchetti B, Leggio L, L'Episcopo F, Vivarelli S, Tirolo C, Paternò G, Giachino C, Caniglia S, Serapide MF, Iraci N. Glia-Derived Extracellular Vesicles in Parkinson's Disease. J Clin Med 2020;9:E1941. [PMID: 32575923 DOI: 10.3390/jcm9061941] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 4.5] [Reference Citation Analysis]
150 Tanik SA, Schultheiss CE, Volpicelli-Daley LA, Brunden KR, Lee VM. Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy. J Biol Chem 2013;288:15194-210. [PMID: 23532841 DOI: 10.1074/jbc.M113.457408] [Cited by in Crossref: 183] [Cited by in F6Publishing: 109] [Article Influence: 20.3] [Reference Citation Analysis]
151 Bougea A, Stefanis L, Paraskevas GP, Emmanouilidou E, Vekrelis K, Kapaki E. Plasma alpha-synuclein levels in patients with Parkinson's disease: a systematic review and meta-analysis. Neurol Sci 2019;40:929-38. [PMID: 30715632 DOI: 10.1007/s10072-019-03738-1] [Cited by in Crossref: 28] [Cited by in F6Publishing: 24] [Article Influence: 9.3] [Reference Citation Analysis]
152 Sepúlveda D, Cisternas-olmedo M, Arcos J, Nassif M, Vidal RL. Contribution of Autophagy-Lysosomal Pathway in the Exosomal Secretion of Alpha-Synuclein and Its Impact in the Progression of Parkinson’s Disease. Front Mol Neurosci 2022;15:805087. [DOI: 10.3389/fnmol.2022.805087] [Reference Citation Analysis]
153 Castro-Seoane R, Hummerich H, Sweeting T, Tattum MH, Linehan JM, Fernandez de Marco M, Brandner S, Collinge J, Klöhn PC. Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. PLoS Pathog 2012;8:e1002538. [PMID: 22359509 DOI: 10.1371/journal.ppat.1002538] [Cited by in Crossref: 36] [Cited by in F6Publishing: 33] [Article Influence: 3.6] [Reference Citation Analysis]
154 Gassama Y, Favereaux A. Emerging Roles of Extracellular Vesicles in the Central Nervous System: Physiology, Pathology, and Therapeutic Perspectives. Front Cell Neurosci 2021;15:626043. [PMID: 33708073 DOI: 10.3389/fncel.2021.626043] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
155 Ciregia F, Urbani A, Palmisano G. Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases. Front Mol Neurosci 2017;10:276. [PMID: 28912682 DOI: 10.3389/fnmol.2017.00276] [Cited by in Crossref: 53] [Cited by in F6Publishing: 52] [Article Influence: 10.6] [Reference Citation Analysis]
156 Busquets MA, Espargaró A, Estelrich J, Sabate R. Could α-synuclein amyloid-like aggregates trigger a prionic neuronal invasion? Biomed Res Int 2015;2015:172018. [PMID: 25866763 DOI: 10.1155/2015/172018] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
157 Tang BL. Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin. Cells 2018;7:E59. [PMID: 29904030 DOI: 10.3390/cells7060059] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 3.0] [Reference Citation Analysis]
158 Lashuel HA, Overk CR, Oueslati A, Masliah E. The many faces of α-synuclein: from structure and toxicity to therapeutic target. Nat Rev Neurosci 2013;14:38-48. [PMID: 23254192 DOI: 10.1038/nrn3406] [Cited by in Crossref: 869] [Cited by in F6Publishing: 798] [Article Influence: 96.6] [Reference Citation Analysis]
159 Iliescu FS, Vrtačnik D, Neuzil P, Iliescu C. Microfluidic Technology for Clinical Applications of Exosomes. Micromachines (Basel) 2019;10:E392. [PMID: 31212754 DOI: 10.3390/mi10060392] [Cited by in Crossref: 22] [Cited by in F6Publishing: 19] [Article Influence: 7.3] [Reference Citation Analysis]
160 Okada T, Hirai C, Badawy SMM, Zhang L, Kajimoto T, Nakamura SI. Impairment of PDGF-induced chemotaxis by extracellular α-synuclein through selective inhibition of Rac1 activation. Sci Rep 2016;6:37810. [PMID: 27886249 DOI: 10.1038/srep37810] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
161 Kalra H, Drummen GP, Mathivanan S. Focus on Extracellular Vesicles: Introducing the Next Small Big Thing. Int J Mol Sci 2016;17:170. [PMID: 26861301 DOI: 10.3390/ijms17020170] [Cited by in Crossref: 362] [Cited by in F6Publishing: 349] [Article Influence: 60.3] [Reference Citation Analysis]
162 Perez-Gonzalez R, Gauthier SA, Kumar A, Levy E. The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space. J Biol Chem. 2012;287:43108-43115. [PMID: 23129776 DOI: 10.1074/jbc.m112.404467] [Cited by in Crossref: 207] [Cited by in F6Publishing: 158] [Article Influence: 20.7] [Reference Citation Analysis]
163 Guo YJ, Xiong H, Chen K, Zou JJ, Lei P. Brain regions susceptible to alpha-synuclein spreading. Mol Psychiatry 2021. [PMID: 34561613 DOI: 10.1038/s41380-021-01296-7] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
164 Zheng T, Zhao C, Zhao B, Liu H, Wang S, Wang L, Liu P. Impairment of the autophagy-lysosomal pathway and activation of pyroptosis in macular corneal dystrophy. Cell Death Discov 2020;6:85. [PMID: 32983576 DOI: 10.1038/s41420-020-00320-z] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
165 Lee J, Ye Y. The Roles of Endo-Lysosomes in Unconventional Protein Secretion. Cells 2018;7:E198. [PMID: 30400277 DOI: 10.3390/cells7110198] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 3.8] [Reference Citation Analysis]
166 Vatsa P, Negi R, Ansari UA, Khanna VK, Pant AB. Insights of Extracellular Vesicles of Mesenchymal Stem Cells: a Prospective Cell-Free Regenerative Medicine for Neurodegenerative Disorders. Mol Neurobiol 2021. [PMID: 34714469 DOI: 10.1007/s12035-021-02603-7] [Reference Citation Analysis]
167 Grassi S, Giussani P, Mauri L, Prioni S, Sonnino S, Prinetti A. Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases. J Lipid Res 2020;61:636-54. [PMID: 31871065 DOI: 10.1194/jlr.TR119000427] [Cited by in Crossref: 22] [Cited by in F6Publishing: 17] [Article Influence: 7.3] [Reference Citation Analysis]
168 Beatriz M, Vilaça R, Lopes C. Exosomes: Innocent Bystanders or Critical Culprits in Neurodegenerative Diseases. Front Cell Dev Biol 2021;9:635104. [PMID: 34055771 DOI: 10.3389/fcell.2021.635104] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
169 Cerri S, Ghezzi C, Ongari G, Croce S, Avenali M, Zangaglia R, Di Monte DA, Valente EM, Blandini F. GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease. Int J Mol Sci 2021;22:2215. [PMID: 33672321 DOI: 10.3390/ijms22042215] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
170 Cossetti C, Smith JA, Iraci N, Leonardi T, Alfaro-Cervello C, Pluchino S. Extracellular membrane vesicles and immune regulation in the brain. Front Physiol 2012;3:117. [PMID: 22557978 DOI: 10.3389/fphys.2012.00117] [Cited by in Crossref: 39] [Cited by in F6Publishing: 35] [Article Influence: 3.9] [Reference Citation Analysis]
171 Okuzumi A, Kurosawa M, Hatano T, Takanashi M, Nojiri S, Fukuhara T, Yamanaka T, Miyazaki H, Yoshinaga S, Furukawa Y, Shimogori T, Hattori N, Nukina N. Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment. Acta Neuropathol Commun 2018;6:96. [PMID: 30231908 DOI: 10.1186/s40478-018-0587-0] [Cited by in Crossref: 29] [Cited by in F6Publishing: 27] [Article Influence: 7.3] [Reference Citation Analysis]
172 Li XH, Zhang J, Li DF, Wu W, Xie ZW, Liu Q. Physiological and pathological insights into exosomes in the brain. Zool Res 2020;41:365-72. [PMID: 32400978 DOI: 10.24272/j.issn.2095-8137.2020.043] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
173 Gendreau KL, Hall GF. Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing Problem. Front Neurol 2013;4:160. [PMID: 24151487 DOI: 10.3389/fneur.2013.00160] [Cited by in Crossref: 35] [Cited by in F6Publishing: 37] [Article Influence: 3.9] [Reference Citation Analysis]
174 Wu Q, Shaikh MA, Meymand ES, Zhang B, Luk KC, Trojanowski JQ, Lee VM. Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo. Acta Neuropathol 2020;140:831-49. [PMID: 33021680 DOI: 10.1007/s00401-020-02227-6] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
175 Xu L, Pu J. Alpha-Synuclein in Parkinson's Disease: From Pathogenetic Dysfunction to Potential Clinical Application. Parkinsons Dis 2016;2016:1720621. [PMID: 27610264 DOI: 10.1155/2016/1720621] [Cited by in Crossref: 51] [Cited by in F6Publishing: 56] [Article Influence: 8.5] [Reference Citation Analysis]
176 Schiera G, Di Liegro CM, Di Liegro I. Extracellular Membrane Vesicles as Vehicles for Brain Cell-to-Cell Interactions in Physiological as well as Pathological Conditions. Biomed Res Int 2015;2015:152926. [PMID: 26583089 DOI: 10.1155/2015/152926] [Cited by in Crossref: 37] [Cited by in F6Publishing: 38] [Article Influence: 5.3] [Reference Citation Analysis]
177 Wood LB, Winslow AR, Strasser SD. Systems biology of neurodegenerative diseases. Integr Biol (Camb). 2015;7:758-775. [PMID: 26065845 DOI: 10.1039/c5ib00031a] [Cited by in Crossref: 26] [Cited by in F6Publishing: 9] [Article Influence: 4.3] [Reference Citation Analysis]
178 Stefanini AC, da Cunha BR, Henrique T, Tajara EH. Involvement of Kallikrein-Related Peptidases in Normal and Pathologic Processes. Dis Markers 2015;2015:946572. [PMID: 26783378 DOI: 10.1155/2015/946572] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 2.7] [Reference Citation Analysis]
179 Harischandra DS, Ghaisas S, Rokad D, Kanthasamy AG. Exosomes in Toxicology: Relevance to Chemical Exposure and Pathogenesis of Environmentally Linked Diseases. Toxicol Sci 2017;158:3-13. [PMID: 28505322 DOI: 10.1093/toxsci/kfx074] [Cited by in Crossref: 24] [Cited by in F6Publishing: 22] [Article Influence: 6.0] [Reference Citation Analysis]
180 Mattson MP, Arumugam TV. Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States. Cell Metab 2018;27:1176-99. [PMID: 29874566 DOI: 10.1016/j.cmet.2018.05.011] [Cited by in Crossref: 245] [Cited by in F6Publishing: 222] [Article Influence: 81.7] [Reference Citation Analysis]
181 Kam TI, Mao X, Park H, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmachari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, Bekris LM, Leverenz JB, Pantelyat A, Ko HS, Rosenthal LS, Dawson TM, Dawson VL. Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease. Science 2018;362:eaat8407. [PMID: 30385548 DOI: 10.1126/science.aat8407] [Cited by in Crossref: 151] [Cited by in F6Publishing: 133] [Article Influence: 37.8] [Reference Citation Analysis]
182 He C, Zheng S, Luo Y, Wang B. Exosome Theranostics: Biology and Translational Medicine. Theranostics 2018;8:237-55. [PMID: 29290805 DOI: 10.7150/thno.21945] [Cited by in Crossref: 211] [Cited by in F6Publishing: 244] [Article Influence: 52.8] [Reference Citation Analysis]
183 Leandrou E, Emmanouilidou E, Vekrellis K. Voltage-Gated Calcium Channels and α-Synuclein: Implications in Parkinson's Disease. Front Mol Neurosci 2019;12:237. [PMID: 31649506 DOI: 10.3389/fnmol.2019.00237] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 3.7] [Reference Citation Analysis]
184 Harischandra DS, Ghaisas S, Rokad D, Zamanian M, Jin H, Anantharam V, Kimber M, Kanthasamy A, Kanthasamy AG. Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity. Neurotoxicology 2018;64:267-77. [PMID: 28450057 DOI: 10.1016/j.neuro.2017.04.007] [Cited by in Crossref: 40] [Cited by in F6Publishing: 41] [Article Influence: 8.0] [Reference Citation Analysis]
185 Moreira R, Mendonça LS, Pereira de Almeida L. Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases. Int J Mol Sci 2021;22:12288. [PMID: 34830171 DOI: 10.3390/ijms222212288] [Reference Citation Analysis]
186 Niu C, Wang X, Zhao M, Cai T, Liu P, Li J, Willard B, Zu L, Zhou E, Li Y, Pan B, Yang F, Zheng L. Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion. J Am Heart Assoc 2016;5:e004099. [PMID: 27792649 DOI: 10.1161/JAHA.116.004099] [Cited by in Crossref: 50] [Cited by in F6Publishing: 39] [Article Influence: 8.3] [Reference Citation Analysis]
187 Chaudhuri AD, Dastgheyb RM, Yoo SW, Trout A, Talbot CC Jr, Hao H, Witwer KW, Haughey NJ. TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons. Cell Death Dis 2018;9:363. [PMID: 29507357 DOI: 10.1038/s41419-018-0369-4] [Cited by in Crossref: 62] [Cited by in F6Publishing: 66] [Article Influence: 15.5] [Reference Citation Analysis]
188 Brundin P, Ma J, Kordower JH. How strong is the evidence that Parkinson's disease is a prion disorder? Curr Opin Neurol 2016;29:459-66. [PMID: 27257944 DOI: 10.1097/WCO.0000000000000349] [Cited by in Crossref: 43] [Cited by in F6Publishing: 19] [Article Influence: 7.2] [Reference Citation Analysis]
189 Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, Takeda A. The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein. PLoS One 2011;6:e29460. [PMID: 22216284 DOI: 10.1371/journal.pone.0029460] [Cited by in Crossref: 96] [Cited by in F6Publishing: 96] [Article Influence: 8.7] [Reference Citation Analysis]
190 Simon C, Soga T, Okano HJ, Parhar I. α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox. Cell Biosci 2021;11:196. [PMID: 34798911 DOI: 10.1186/s13578-021-00709-y] [Reference Citation Analysis]
191 Bendor JT, Logan TP, Edwards RH. The function of α-synuclein. Neuron 2013;79:1044-66. [PMID: 24050397 DOI: 10.1016/j.neuron.2013.09.004] [Cited by in Crossref: 407] [Cited by in F6Publishing: 367] [Article Influence: 45.2] [Reference Citation Analysis]
192 Uchihara T, Giasson BI. Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies. Acta Neuropathol 2016;131:49-73. [PMID: 26446103 DOI: 10.1007/s00401-015-1485-1] [Cited by in Crossref: 114] [Cited by in F6Publishing: 106] [Article Influence: 16.3] [Reference Citation Analysis]
193 Fuller OK, Whitham M, Mathivanan S, Febbraio MA. The Protective Effect of Exercise in Neurodegenerative Diseases: The Potential Role of Extracellular Vesicles. Cells 2020;9:E2182. [PMID: 32998245 DOI: 10.3390/cells9102182] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 3.5] [Reference Citation Analysis]
194 Ngolab J, Trinh I, Rockenstein E, Mante M, Florio J, Trejo M, Masliah D, Adame A, Masliah E, Rissman RA. Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology. Acta Neuropathol Commun 2017;5:46. [PMID: 28599681 DOI: 10.1186/s40478-017-0445-5] [Cited by in Crossref: 97] [Cited by in F6Publishing: 94] [Article Influence: 19.4] [Reference Citation Analysis]
195 Hejjaoui M, Butterfield S, Fauvet B, Vercruysse F, Cui J, Dikiy I, Prudent M, Olschewski D, Zhang Y, Eliezer D, Lashuel HA. Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125. J Am Chem Soc 2012;134:5196-210. [PMID: 22339654 DOI: 10.1021/ja210866j] [Cited by in Crossref: 71] [Cited by in F6Publishing: 67] [Article Influence: 7.1] [Reference Citation Analysis]
196 Reza-Zaldivar EE, Hernández-Sapiéns MA, Minjarez B, Gutiérrez-Mercado YK, Márquez-Aguirre AL, Canales-Aguirre AA. Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer's Disease. Front Cell Neurosci 2018;12:317. [PMID: 30319358 DOI: 10.3389/fncel.2018.00317] [Cited by in Crossref: 54] [Cited by in F6Publishing: 62] [Article Influence: 13.5] [Reference Citation Analysis]
197 Shen Y, Guo X, Han C, Wan F, Ma K, Guo S, Wang L, Xia Y, Liu L, Lin Z, Huang J, Xiong N, Wang T. The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease. Cell Mol Life Sci 2017;74:3741-68. [PMID: 28623510 DOI: 10.1007/s00018-017-2549-2] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
198 Creed RB, Roberts RC, Farmer CB, McMahon LL, Goldberg MS. Increased glutamate transmission onto dorsal striatum spiny projection neurons in Pink1 knockout rats. Neurobiol Dis 2021;150:105246. [PMID: 33387634 DOI: 10.1016/j.nbd.2020.105246] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
199 Fellner L, Stefanova N. The role of glia in α-synucleinopathies. Mol Neurobiol 2013;47:575-86. [PMID: 22941028 DOI: 10.1007/s12035-012-8340-3] [Cited by in Crossref: 48] [Cited by in F6Publishing: 49] [Article Influence: 4.8] [Reference Citation Analysis]
200 Guo JL, Lee VM. Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases. Nat Med. 2014;20:130-138. [PMID: 24504409 DOI: 10.1038/nm.3457] [Cited by in Crossref: 394] [Cited by in F6Publishing: 364] [Article Influence: 49.3] [Reference Citation Analysis]
201 Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH, Schneider A. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathol 2015;129:695-713. [PMID: 25778619 DOI: 10.1007/s00401-015-1408-1] [Cited by in Crossref: 86] [Cited by in F6Publishing: 86] [Article Influence: 12.3] [Reference Citation Analysis]
202 Rokad D, Ghaisas S, Harischandra DS, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation. Brain Res Bull 2017;133:60-70. [PMID: 27993598 DOI: 10.1016/j.brainresbull.2016.12.003] [Cited by in Crossref: 22] [Cited by in F6Publishing: 23] [Article Influence: 3.7] [Reference Citation Analysis]
203 Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT. Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Cell 2021;184:5089-5106.e21. [PMID: 34555357 DOI: 10.1016/j.cell.2021.09.007] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
204 Badiola N, de Oliveira RM, Herrera F, Guardia-Laguarta C, Gonçalves SA, Pera M, Suárez-Calvet M, Clarimon J, Outeiro TF, Lleó A. Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy. PLoS One 2011;6:e26609. [PMID: 22039514 DOI: 10.1371/journal.pone.0026609] [Cited by in Crossref: 81] [Cited by in F6Publishing: 80] [Article Influence: 7.4] [Reference Citation Analysis]
205 Sullivan R, Maresh G, Zhang X, Salomon C, Hooper J, Margolin D, Li L. The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond. Front Endocrinol (Lausanne) 2017;8:194. [PMID: 28848498 DOI: 10.3389/fendo.2017.00194] [Cited by in Crossref: 35] [Cited by in F6Publishing: 39] [Article Influence: 7.0] [Reference Citation Analysis]
206 Lopes da Fonseca T, Villar-Piqué A, Outeiro TF. The Interplay between Alpha-Synuclein Clearance and Spreading. Biomolecules 2015;5:435-71. [PMID: 25874605 DOI: 10.3390/biom5020435] [Cited by in Crossref: 54] [Cited by in F6Publishing: 57] [Article Influence: 7.7] [Reference Citation Analysis]
207 Lopes DM, Llewellyn SK, Harrison IF. Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system. Transl Neurodegener 2022;11. [DOI: 10.1186/s40035-022-00293-2] [Reference Citation Analysis]
208 Kaufman SK, Diamond MI. Prion-like propagation of protein aggregation and related therapeutic strategies. Neurotherapeutics 2013;10:371-82. [PMID: 23801258 DOI: 10.1007/s13311-013-0196-3] [Cited by in Crossref: 23] [Cited by in F6Publishing: 23] [Article Influence: 2.9] [Reference Citation Analysis]
209 Lee HJ, Bae EJ, Lee SJ. Extracellular α--synuclein-a novel and crucial factor in Lewy body diseases. Nat Rev Neurol 2014;10:92-8. [PMID: 24468877 DOI: 10.1038/nrneurol.2013.275] [Cited by in Crossref: 181] [Cited by in F6Publishing: 180] [Article Influence: 22.6] [Reference Citation Analysis]
210 Schiess MC, Barnes JL, Ellmore TM, Poindexter BJ, Dinh K, Bick RJ. CSF from Parkinson disease patients differentially affects cultured microglia and astrocytes. BMC Neurosci 2010;11:151. [PMID: 21114836 DOI: 10.1186/1471-2202-11-151] [Cited by in Crossref: 11] [Cited by in F6Publishing: 13] [Article Influence: 0.9] [Reference Citation Analysis]
211 Grey M, Dunning CJ, Gaspar R, Grey C, Brundin P, Sparr E, Linse S. Acceleration of α-synuclein aggregation by exosomes. J Biol Chem 2015;290:2969-82. [PMID: 25425650 DOI: 10.1074/jbc.M114.585703] [Cited by in Crossref: 196] [Cited by in F6Publishing: 121] [Article Influence: 24.5] [Reference Citation Analysis]
212 EL Andaloussi S, Mäger I, Breakefield XO, Wood MJ. Extracellular vesicles: biology and emerging therapeutic opportunities. Nat Rev Drug Discov 2013;12:347-57. [PMID: 23584393 DOI: 10.1038/nrd3978] [Cited by in Crossref: 1564] [Cited by in F6Publishing: 1515] [Article Influence: 173.8] [Reference Citation Analysis]
213 Bae EJ, Yang NY, Lee C, Kim S, Lee HJ, Lee SJ. Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates. Cell Death Dis 2015;6:e1901. [PMID: 26448324 DOI: 10.1038/cddis.2015.283] [Cited by in Crossref: 43] [Cited by in F6Publishing: 43] [Article Influence: 6.1] [Reference Citation Analysis]
214 Yuyama K, Sun H, Mitsutake S, Igarashi Y. Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia. J Biol Chem 2012;287:10977-89. [PMID: 22303002 DOI: 10.1074/jbc.M111.324616] [Cited by in Crossref: 300] [Cited by in F6Publishing: 212] [Article Influence: 30.0] [Reference Citation Analysis]
215 Sun T, Ding ZX, Luo X, Liu QS, Cheng Y. Blood Exosomes Have Neuroprotective Effects in a Mouse Model of Parkinson's Disease. Oxid Med Cell Longev 2020;2020:3807476. [PMID: 33294121 DOI: 10.1155/2020/3807476] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
216 Killinger BA, Labrie V. Vertebrate food products as a potential source of prion-like α-synuclein. NPJ Parkinsons Dis 2017;3:33. [PMID: 29184902 DOI: 10.1038/s41531-017-0035-z] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 2.8] [Reference Citation Analysis]
217 Boza-Serrano A, Yang Y, Paulus A, Deierborg T. Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer's disease mouse model 5xFAD. Sci Rep 2018;8:1550. [PMID: 29367720 DOI: 10.1038/s41598-018-19699-y] [Cited by in Crossref: 45] [Cited by in F6Publishing: 41] [Article Influence: 11.3] [Reference Citation Analysis]
218 Zhang L, Okada T, Badawy SMM, Hirai C, Kajimoto T, Nakamura SI. Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact. Sci Rep 2017;7:44248. [PMID: 28300069 DOI: 10.1038/srep44248] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.8] [Reference Citation Analysis]
219 Rastogi S, Sharma V, Bharti PS, Rani K, Modi GP, Nikolajeff F, Kumar S. The Evolving Landscape of Exosomes in Neurodegenerative Diseases: Exosomes Characteristics and a Promising Role in Early Diagnosis. Int J Mol Sci 2021;22:E440. [PMID: 33406804 DOI: 10.3390/ijms22010440] [Cited by in Crossref: 7] [Cited by in F6Publishing: 10] [Article Influence: 7.0] [Reference Citation Analysis]
220 Wang S, West AB. Caught in the act: LRRK2 in exosomes. Biochem Soc Trans 2019;47:663-70. [PMID: 30837321 DOI: 10.1042/BST20180467] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 3.0] [Reference Citation Analysis]
221 Bieri G, Gitler AD, Brahic M. Internalization, axonal transport and release of fibrillar forms of alpha-synuclein. Neurobiol Dis 2018;109:219-25. [PMID: 28323023 DOI: 10.1016/j.nbd.2017.03.007] [Cited by in Crossref: 43] [Cited by in F6Publishing: 44] [Article Influence: 8.6] [Reference Citation Analysis]
222 de Rivero Vaccari JP, Brand F 3rd, Adamczak S, Lee SW, Perez-Barcena J, Wang MY, Bullock MR, Dietrich WD, Keane RW. Exosome-mediated inflammasome signaling after central nervous system injury. J Neurochem 2016;136 Suppl 1:39-48. [PMID: 25628216 DOI: 10.1111/jnc.13036] [Cited by in Crossref: 109] [Cited by in F6Publishing: 114] [Article Influence: 15.6] [Reference Citation Analysis]
223 Di Liegro CM, Schiera G, Di Liegro I. Extracellular Vesicle-Associated RNA as a Carrier of Epigenetic Information. Genes (Basel) 2017;8:E240. [PMID: 28937658 DOI: 10.3390/genes8100240] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 4.6] [Reference Citation Analysis]
224 Jurj A, Pop-Bica C, Slaby O, Ştefan CD, Cho WC, Korban SS, Berindan-Neagoe I. Tiny Actors in the Big Cellular World: Extracellular Vesicles Playing Critical Roles in Cancer. Int J Mol Sci 2020;21:E7688. [PMID: 33080788 DOI: 10.3390/ijms21207688] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
225 Yu H, Sun T, An J, Wen L, Liu F, Bu Z, Cui Y, Feng J. Potential Roles of Exosomes in Parkinson's Disease: From Pathogenesis, Diagnosis, and Treatment to Prognosis. Front Cell Dev Biol 2020;8:86. [PMID: 32154247 DOI: 10.3389/fcell.2020.00086] [Cited by in Crossref: 29] [Cited by in F6Publishing: 26] [Article Influence: 14.5] [Reference Citation Analysis]
226 Zhang S, Eitan E, Wu TY, Mattson MP. Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal. Neurobiol Aging 2018;61:52-65. [PMID: 29035751 DOI: 10.1016/j.neurobiolaging.2017.09.016] [Cited by in Crossref: 31] [Cited by in F6Publishing: 27] [Article Influence: 6.2] [Reference Citation Analysis]
227 Krejciova Z, Carlson GA, Giles K, Prusiner SB. Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein. Acta Neuropathol Commun 2019;7:81. [PMID: 31109379 DOI: 10.1186/s40478-019-0703-9] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 3.0] [Reference Citation Analysis]
228 Cisterna BA, Cardozo C, Sáez JC. Neuronal involvement in muscular atrophy. Front Cell Neurosci 2014;8:405. [PMID: 25540609 DOI: 10.3389/fncel.2014.00405] [Cited by in Crossref: 28] [Cited by in F6Publishing: 25] [Article Influence: 3.5] [Reference Citation Analysis]
229 Ge Y, Xu K. Alpha-synuclein contributes to malignant progression of human meningioma via the Akt/mTOR pathway. Cancer Cell Int 2016;16:86. [PMID: 27895530 DOI: 10.1186/s12935-016-0361-y] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 2.0] [Reference Citation Analysis]
230 Krauss S, Vorberg I. Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins. Int J Cell Biol 2013;2013:704546. [PMID: 24282413 DOI: 10.1155/2013/704546] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 1.7] [Reference Citation Analysis]
231 Baharlooi H, Azimi M, Salehi Z, Izad M. Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Ace Card to Address Autoimmune Diseases. Int J Stem Cells 2020;13:13-23. [PMID: 31887849 DOI: 10.15283/ijsc19108] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 8.5] [Reference Citation Analysis]
232 Mi X, Li Q, Wen X, Xie J, Wang Y, Song N. Extracellular α-Synuclein Modulates Iron Metabolism Related Proteins via Endoplasmic Reticulum Stress in MES23.5 Dopaminergic Cells. Neurochem Res 2021;46:1502-13. [PMID: 33704649 DOI: 10.1007/s11064-021-03292-3] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
233 Mbefo MK, Fares MB, Paleologou K, Oueslati A, Yin G, Tenreiro S, Pinto M, Outeiro T, Zweckstetter M, Masliah E, Lashuel HA. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. J Biol Chem 2015;290:9412-27. [PMID: 25657004 DOI: 10.1074/jbc.M114.610774] [Cited by in Crossref: 39] [Cited by in F6Publishing: 24] [Article Influence: 5.6] [Reference Citation Analysis]
234 Guillot-Sestier MV, Town T. Let's make microglia great again in neurodegenerative disorders. J Neural Transm (Vienna) 2018;125:751-70. [PMID: 29027011 DOI: 10.1007/s00702-017-1792-x] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 2.6] [Reference Citation Analysis]
235 Schneider A, Simons M. Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders. Cell Tissue Res. 2013;352:33-47. [PMID: 22610588 DOI: 10.1007/s00441-012-1428-2] [Cited by in Crossref: 189] [Cited by in F6Publishing: 194] [Article Influence: 18.9] [Reference Citation Analysis]
236 Tansey MG, Romero-Ramos M. Immune system responses in Parkinson's disease: Early and dynamic. Eur J Neurosci 2019;49:364-83. [PMID: 30474172 DOI: 10.1111/ejn.14290] [Cited by in Crossref: 30] [Cited by in F6Publishing: 32] [Article Influence: 7.5] [Reference Citation Analysis]
237 Surguchev AA, Emamzadeh FN, Surguchov A. Cell Responses to Extracellular α-Synuclein. Molecules 2019;24:E305. [PMID: 30650656 DOI: 10.3390/molecules24020305] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 5.7] [Reference Citation Analysis]
238 Zhao X, Guan Y, Liu F, Yan S, Wang Y, Hu M, Li Y, Li R, Zhang CX. SNARE Proteins Mediate α-Synuclein Secretion via Multiple Vesicular Pathways. Mol Neurobiol 2021. [PMID: 34705229 DOI: 10.1007/s12035-021-02599-0] [Reference Citation Analysis]
239 McAndrews KM, Kalluri R. Mechanisms associated with biogenesis of exosomes in cancer. Mol Cancer. 2019;18:52. [PMID: 30925917 DOI: 10.1186/s12943-019-0963-9] [Cited by in Crossref: 91] [Cited by in F6Publishing: 103] [Article Influence: 30.3] [Reference Citation Analysis]
240 Valdinocci D, Radford RA, Siow SM, Chung RS, Pountney DL. Potential Modes of Intercellular α-Synuclein Transmission. Int J Mol Sci 2017;18:E469. [PMID: 28241427 DOI: 10.3390/ijms18020469] [Cited by in Crossref: 47] [Cited by in F6Publishing: 49] [Article Influence: 9.4] [Reference Citation Analysis]
241 Du XY, Xie XX, Liu RT. The Role of α-Synuclein Oligomers in Parkinson's Disease. Int J Mol Sci 2020;21:E8645. [PMID: 33212758 DOI: 10.3390/ijms21228645] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 4.0] [Reference Citation Analysis]
242 Wong Su S, Chieng A, Parres-Gold J, Chang M, Wang Y. Real-time determination of aggregated alpha-synuclein induced membrane disruption at neuroblastoma cells using scanning ion conductance microscopy. Faraday Discuss 2018;210:131-43. [PMID: 29974096 DOI: 10.1039/c8fd00059j] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 1.3] [Reference Citation Analysis]
243 Brettschneider J, Del Tredici K, Lee VM, Trojanowski JQ. Spreading of pathology in neurodegenerative diseases: a focus on human studies. Nat Rev Neurosci 2015;16:109-20. [PMID: 25588378 DOI: 10.1038/nrn3887] [Cited by in Crossref: 448] [Cited by in F6Publishing: 399] [Article Influence: 64.0] [Reference Citation Analysis]
244 Smith JA, Leonardi T, Huang B, Iraci N, Vega B, Pluchino S. Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases. Biogerontology 2015;16:147-85. [PMID: 24973266 DOI: 10.1007/s10522-014-9510-7] [Cited by in Crossref: 39] [Cited by in F6Publishing: 34] [Article Influence: 4.9] [Reference Citation Analysis]
245 Jin Q, Wu P, Zhou X, Qian H, Xu W. Extracellular Vesicles: Novel Roles in Neurological Disorders. Stem Cells Int 2021;2021:6640836. [PMID: 33679989 DOI: 10.1155/2021/6640836] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
246 Peng W, Minakaki G, Nguyen M, Krainc D. Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration. Neurotherapeutics 2019;16:611-34. [PMID: 31183763 DOI: 10.1007/s13311-019-00742-3] [Cited by in Crossref: 20] [Cited by in F6Publishing: 20] [Article Influence: 10.0] [Reference Citation Analysis]
247 Ross A, Xing V, Wang TT, Bureau SC, Link GA, Fortin T, Zhang H, Hayley S, Sun H. Alleviating toxic α-Synuclein accumulation by membrane depolarization: evidence from an in vitro model of Parkinson's disease. Mol Brain 2020;13:108. [PMID: 32736645 DOI: 10.1186/s13041-020-00648-8] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
248 Frühbeis C, Fröhlich D, Krämer-Albers EM. Emerging roles of exosomes in neuron-glia communication. Front Physiol 2012;3:119. [PMID: 22557979 DOI: 10.3389/fphys.2012.00119] [Cited by in Crossref: 158] [Cited by in F6Publishing: 160] [Article Influence: 15.8] [Reference Citation Analysis]
249 Fan TS, Liu SC, Wu RM. Alpha-Synuclein and Cognitive Decline in Parkinson Disease. Life (Basel) 2021;11:1239. [PMID: 34833115 DOI: 10.3390/life11111239] [Reference Citation Analysis]
250 Kanthasamy A, Jin H, Charli A, Vellareddy A, Kanthasamy A. Environmental neurotoxicant-induced dopaminergic neurodegeneration: a potential link to impaired neuroinflammatory mechanisms. Pharmacol Ther 2019;197:61-82. [PMID: 30677475 DOI: 10.1016/j.pharmthera.2019.01.001] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 3.3] [Reference Citation Analysis]
251 Yoshida S, Hasegawa T. Deciphering the prion-like behavior of pathogenic protein aggregates in neurodegenerative diseases. Neurochem Int 2022;:105307. [PMID: 35181393 DOI: 10.1016/j.neuint.2022.105307] [Reference Citation Analysis]
252 Falkenburger BH. N-terminal fusion potentiates α-synuclein secretion [correction]. Cell Mol Neurobiol 2018;38:1551-4. [PMID: 30288630 DOI: 10.1007/s10571-018-0621-6] [Cited by in Crossref: 1] [Article Influence: 0.3] [Reference Citation Analysis]
253 Svarcbahs R, Julku UH, Norrbacka S, Myöhänen TT. Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo. Sci Rep 2018;8:1552. [PMID: 29367610 DOI: 10.1038/s41598-018-19823-y] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 4.0] [Reference Citation Analysis]
254 Sterzenbach U, Putz U, Low LH, Silke J, Tan SS, Howitt J. Engineered Exosomes as Vehicles for Biologically Active Proteins. Mol Ther 2017;25:1269-78. [PMID: 28412169 DOI: 10.1016/j.ymthe.2017.03.030] [Cited by in Crossref: 119] [Cited by in F6Publishing: 122] [Article Influence: 23.8] [Reference Citation Analysis]
255 Bryl R, Borowiec B, Siroma RS, Pinto N, Melo MA, Shibli JA, Dyszkiewicz-konwińska M. Current application of exosomes in medicine. Medical Journal of Cell Biology 2020;8:101-11. [DOI: 10.2478/acb-2020-0013] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 1.5] [Reference Citation Analysis]
256 Hebron ML, Lonskaya I, Moussa CE. Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models. Hum Mol Genet 2013;22:3315-28. [PMID: 23666528 DOI: 10.1093/hmg/ddt192] [Cited by in Crossref: 181] [Cited by in F6Publishing: 178] [Article Influence: 20.1] [Reference Citation Analysis]
257 Ray B, Mahalakshmi AM, Tuladhar S, Bhat A, Srinivasan A, Pellegrino C, Kannan A, Bolla SR, Chidambaram SB, Sakharkar MK. "Janus-Faced" α-Synuclein: Role in Parkinson's Disease. Front Cell Dev Biol 2021;9:673395. [PMID: 34124057 DOI: 10.3389/fcell.2021.673395] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
258 Karampetsou M, Sykioti VS, Leandrou E, Melachroinou K, Lambiris A, Giannelos A, Emmanouilidou E, Vekrellis K. Intrastriatal Administration of Exosome-Associated Pathological Alpha-Synuclein Is Not Sufficient by Itself to Cause Pathology Transmission. Front Neurosci 2020;14:246. [PMID: 32372894 DOI: 10.3389/fnins.2020.00246] [Cited by in Crossref: 5] [Cited by in F6Publishing: 2] [Article Influence: 2.5] [Reference Citation Analysis]
259 Ridder K, Keller S, Dams M, Rupp AK, Schlaudraff J, Del Turco D, Starmann J, Macas J, Karpova D, Devraj K, Depboylu C, Landfried B, Arnold B, Plate KH, Höglinger G, Sültmann H, Altevogt P, Momma S. Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. PLoS Biol 2014;12:e1001874. [PMID: 24893313 DOI: 10.1371/journal.pbio.1001874] [Cited by in Crossref: 202] [Cited by in F6Publishing: 206] [Article Influence: 25.3] [Reference Citation Analysis]
260 Izco M, Carlos E, Alvarez-erviti L. Impact of endolysosomal dysfunction upon exosomes in neurodegenerative diseases. Neurobiology of Disease 2022. [DOI: 10.1016/j.nbd.2022.105651] [Reference Citation Analysis]
261 Abati E, Di Fonzo A, Corti S. In vitro models of multiple system atrophy from primary cells to induced pluripotent stem cells. J Cell Mol Med 2018;22:2536-46. [PMID: 29502349 DOI: 10.1111/jcmm.13563] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 2.5] [Reference Citation Analysis]
262 Zhu C, Bilousova T, Focht S, Jun M, Elias CJ, Melnik M, Chandra S, Campagna J, Cohn W, Hatami A, Spilman P, Gylys KH, John V. Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model. Mol Brain 2021;14:70. [PMID: 33875010 DOI: 10.1186/s13041-021-00776-9] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
263 Aheget H, Mazini L, Martin F, Belqat B, Marchal JA, Benabdellah K. Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases. Cancers (Basel) 2020;13:E84. [PMID: 33396739 DOI: 10.3390/cancers13010084] [Cited by in Crossref: 7] [Cited by in F6Publishing: 9] [Article Influence: 3.5] [Reference Citation Analysis]
264 Wiklander OP, Nordin JZ, O'Loughlin A, Gustafsson Y, Corso G, Mäger I, Vader P, Lee Y, Sork H, Seow Y, Heldring N, Alvarez-Erviti L, Smith CI, Le Blanc K, Macchiarini P, Jungebluth P, Wood MJ, Andaloussi SE. Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting. J Extracell Vesicles 2015;4:26316. [PMID: 25899407 DOI: 10.3402/jev.v4.26316] [Cited by in Crossref: 536] [Cited by in F6Publishing: 540] [Article Influence: 76.6] [Reference Citation Analysis]
265 Hasegawa M, Nonaka T, Masuda-Suzukake M. α-Synuclein: Experimental Pathology. Cold Spring Harb Perspect Med 2016;6:a024273. [PMID: 27481772 DOI: 10.1101/cshperspect.a024273] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 3.7] [Reference Citation Analysis]
266 Vieira BD, Radford RA, Chung RS, Guillemin GJ, Pountney DL. Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation. Front Cell Neurosci 2015;9:437. [PMID: 26778958 DOI: 10.3389/fncel.2015.00437] [Cited by in Crossref: 48] [Cited by in F6Publishing: 47] [Article Influence: 6.9] [Reference Citation Analysis]
267 Urbanelli L, Magini A, Buratta S, Brozzi A, Sagini K, Polchi A, Tancini B, Emiliani C. Signaling pathways in exosomes biogenesis, secretion and fate. Genes (Basel). 2013;4:152-170. [PMID: 24705158 DOI: 10.3390/genes4020152] [Cited by in Crossref: 185] [Cited by in F6Publishing: 192] [Article Influence: 20.6] [Reference Citation Analysis]
268 Caruso Bavisotto C, Scalia F, Marino Gammazza A, Carlisi D, Bucchieri F, Conway de Macario E, Macario AJL, Cappello F, Campanella C. Extracellular Vesicle-Mediated Cell⁻Cell Communication in the Nervous System: Focus on Neurological Diseases. Int J Mol Sci 2019;20:E434. [PMID: 30669512 DOI: 10.3390/ijms20020434] [Cited by in Crossref: 57] [Cited by in F6Publishing: 52] [Article Influence: 19.0] [Reference Citation Analysis]
269 Sharma P, Schiapparelli L, Cline HT. Exosomes function in cell-cell communication during brain circuit development. Curr Opin Neurobiol 2013;23:997-1004. [PMID: 23998929 DOI: 10.1016/j.conb.2013.08.005] [Cited by in Crossref: 45] [Cited by in F6Publishing: 49] [Article Influence: 5.0] [Reference Citation Analysis]
270 Jones LB, Kumar S, Bell CR, Peoples VA, Crenshaw BJ, Coats MT, Scoffield JA, Rowe GC, Sims B, Matthews QL. Effects of Pseudomonas aeruginosa on Microglial-Derived Extracellular Vesicle Biogenesis and Composition. Pathogens 2019;8:E297. [PMID: 31847332 DOI: 10.3390/pathogens8040297] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
271 Tian Y, Fu C, Wu Y, Lu Y, Liu X, Zhang Y. Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases. Oxid Med Cell Longev 2021;2021:9965564. [PMID: 34336127 DOI: 10.1155/2021/9965564] [Reference Citation Analysis]
272 Martin ZS, Neugebauer V, Dineley KT, Kayed R, Zhang W, Reese LC, Taglialatela G. α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases. J Neurochem 2012;120:440-52. [PMID: 22060133 DOI: 10.1111/j.1471-4159.2011.07576.x] [Cited by in Crossref: 69] [Cited by in F6Publishing: 72] [Article Influence: 6.3] [Reference Citation Analysis]
273 Choi YR, Kim JB, Kang SJ, Noh HR, Jou I, Joe EH, Park SM. The dual role of c-src in cell-to-cell transmission of α-synuclein. EMBO Rep 2020;21:e48950. [PMID: 32372484 DOI: 10.15252/embr.201948950] [Cited by in Crossref: 2] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
274 Tofaris GK. A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson's Disease. J Parkinsons Dis 2017;7:569-76. [PMID: 28922170 DOI: 10.3233/JPD-171176] [Cited by in Crossref: 41] [Cited by in F6Publishing: 29] [Article Influence: 10.3] [Reference Citation Analysis]
275 Fernandes HJ, Hartfield EM, Christian HC, Emmanoulidou E, Zheng Y, Booth H, Bogetofte H, Lang C, Ryan BJ, Sardi SP, Badger J, Vowles J, Evetts S, Tofaris GK, Vekrellis K, Talbot K, Hu MT, James W, Cowley SA, Wade-Martins R. ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons. Stem Cell Reports 2016;6:342-56. [PMID: 26905200 DOI: 10.1016/j.stemcr.2016.01.013] [Cited by in Crossref: 172] [Cited by in F6Publishing: 168] [Article Influence: 28.7] [Reference Citation Analysis]
276 Kayed R, Dettmer U, Lesné SE. Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk. J Parkinsons Dis 2020;10:791-818. [PMID: 32508330 DOI: 10.3233/JPD-201965] [Cited by in Crossref: 13] [Cited by in F6Publishing: 8] [Article Influence: 13.0] [Reference Citation Analysis]
277 Yang Y, Keene CD, Peskind ER, Galasko DR, Hu SC, Cudaback E, Wilson AM, Li G, Yu CE, Montine KS, Zhang J, Baird GS, Hyman BT, Montine TJ. Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease. J Neuropathol Exp Neurol 2015;74:672-87. [PMID: 26083568 DOI: 10.1097/NEN.0000000000000207] [Cited by in Crossref: 23] [Cited by in F6Publishing: 13] [Article Influence: 3.3] [Reference Citation Analysis]
278 Chiu CC, Yeh TH, Lai SC, Weng YH, Huang YC, Cheng YC, Chen RS, Huang YZ, Hung J, Chen CC, Lin WY, Chang HC, Chen YJ, Chen CL, Chen HY, Lin YW, Wu-Chou YH, Wang HL, Lu CS. Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson's disease. Oncotarget 2016;7:54215-27. [PMID: 27509057 DOI: 10.18632/oncotarget.11090] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 5.0] [Reference Citation Analysis]
279 Di Liegro CM, Schiera G, Di Liegro I. H1.0 Linker Histone as an Epigenetic Regulator of Cell Proliferation and Differentiation. Genes (Basel) 2018;9:E310. [PMID: 29925815 DOI: 10.3390/genes9060310] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 2.8] [Reference Citation Analysis]
280 Yasuda T, Nakata Y, Mochizuki H. α-Synuclein and neuronal cell death. Mol Neurobiol 2013;47:466-83. [PMID: 22936307 DOI: 10.1007/s12035-012-8327-0] [Cited by in Crossref: 70] [Cited by in F6Publishing: 68] [Article Influence: 7.0] [Reference Citation Analysis]
281 Uemura N, Uemura MT, Luk KC, Lee VM, Trojanowski JQ. Cell-to-Cell Transmission of Tau and α-Synuclein. Trends Mol Med 2020;26:936-52. [PMID: 32371172 DOI: 10.1016/j.molmed.2020.03.012] [Cited by in Crossref: 27] [Cited by in F6Publishing: 25] [Article Influence: 13.5] [Reference Citation Analysis]
282 Brundin P, Melki R. Prying into the Prion Hypothesis for Parkinson's Disease. J Neurosci 2017;37:9808-18. [PMID: 29021298 DOI: 10.1523/JNEUROSCI.1788-16.2017] [Cited by in Crossref: 132] [Cited by in F6Publishing: 82] [Article Influence: 26.4] [Reference Citation Analysis]
283 Luk KC, Kehm VM, Zhang B, O’Brien P, Trojanowski JQ, Lee VM. Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice. J Exp Med. 2012;209:975-986. [PMID: 22508839 DOI: 10.1084/jem.20112457] [Cited by in Crossref: 656] [Cited by in F6Publishing: 638] [Article Influence: 65.6] [Reference Citation Analysis]
284 Vogel A, Upadhya R, Shetty AK. Neural stem cell derived extracellular vesicles: Attributes and prospects for treating neurodegenerative disorders. EBioMedicine 2018;38:273-82. [PMID: 30472088 DOI: 10.1016/j.ebiom.2018.11.026] [Cited by in Crossref: 43] [Cited by in F6Publishing: 47] [Article Influence: 10.8] [Reference Citation Analysis]
285 Underwood R, Wang B, Carico C, Whitaker RH, Placzek WJ, Yacoubian TA. The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein. J Biol Chem 2020;295:8005-16. [PMID: 32350025 DOI: 10.1074/jbc.RA120.013337] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
286 Wong YC, Krainc D. α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies. Nat Med 2017;23:1-13. [PMID: 28170377 DOI: 10.1038/nm.4269] [Cited by in Crossref: 337] [Cited by in F6Publishing: 302] [Article Influence: 67.4] [Reference Citation Analysis]
287 Ferreira JV, Rosa Soares A, Ramalho JS, Ribeiro-Rodrigues T, Máximo C, Zuzarte M, Girão H, Pereira P. Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis. PLoS One 2019;14:e0223790. [PMID: 31613922 DOI: 10.1371/journal.pone.0223790] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 2.3] [Reference Citation Analysis]
288 Wang Q, Han CL, Wang KL, Sui YP, Li ZB, Chen N, Fan SY, Shimabukuro M, Wang F, Meng FG. Integrated analysis of exosomal lncRNA and mRNA expression profiles reveals the involvement of lnc-MKRN2-42:1 in the pathogenesis of Parkinson's disease. CNS Neurosci Ther 2020;26:527-37. [PMID: 31814304 DOI: 10.1111/cns.13277] [Cited by in Crossref: 11] [Cited by in F6Publishing: 18] [Article Influence: 3.7] [Reference Citation Analysis]
289 Wennström M, Surova Y, Hall S, Nilsson C, Minthon L, Boström F, Hansson O, Nielsen HM. Low CSF levels of both α-synuclein and the α-synuclein cleaving enzyme neurosin in patients with synucleinopathy. PLoS One 2013;8:e53250. [PMID: 23308173 DOI: 10.1371/journal.pone.0053250] [Cited by in Crossref: 88] [Cited by in F6Publishing: 88] [Article Influence: 9.8] [Reference Citation Analysis]
290 Wang S, Okun MS, Suslov O, Zheng T, McFarland NR, Vedam-Mai V, Foote KD, Roper SN, Yachnis AT, Siebzehnrubl FA, Steindler DA. Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains. Brain Res 2012;1464:61-72. [PMID: 22652067 DOI: 10.1016/j.brainres.2012.04.039] [Cited by in Crossref: 20] [Cited by in F6Publishing: 23] [Article Influence: 2.0] [Reference Citation Analysis]
291 Odegaard KE, Chand S, Wheeler S, Tiwari S, Flores A, Hernandez J, Savine M, Gowen A, Pendyala G, Yelamanchili SV. Role of Extracellular Vesicles in Substance Abuse and HIV-Related Neurological Pathologies. Int J Mol Sci 2020;21:E6765. [PMID: 32942668 DOI: 10.3390/ijms21186765] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
292 Steindler DA, Okun MS, Scheffler B. Stem cell pathologies and neurological disease. Mod Pathol 2012;25:157-62. [PMID: 22056951 DOI: 10.1038/modpathol.2011.165] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 0.9] [Reference Citation Analysis]
293 Wang JD, Cao YL, Li Q, Yang YP, Jin M, Chen D, Wang F, Wang GH, Qin ZH, Hu LF, Liu CF. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy 2015;11:2057-73. [PMID: 26649942 DOI: 10.1080/15548627.2015.1100930] [Cited by in Crossref: 43] [Cited by in F6Publishing: 46] [Article Influence: 6.1] [Reference Citation Analysis]
294 Marques O, Outeiro TF. Alpha-synuclein: from secretion to dysfunction and death. Cell Death Dis. 2012;3:e350. [PMID: 22825468 DOI: 10.1038/cddis.2012.94] [Cited by in Crossref: 185] [Cited by in F6Publishing: 174] [Article Influence: 18.5] [Reference Citation Analysis]
295 Ha TY, Choi YR, Noh HR, Cha SH, Kim JB, Park SM. Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons. Mol Brain 2021;14:122. [PMID: 34321069 DOI: 10.1186/s13041-021-00834-2] [Reference Citation Analysis]
296 Lee SJ, Lim HS, Masliah E, Lee HJ. Protein aggregate spreading in neurodegenerative diseases: problems and perspectives. Neurosci Res 2011;70:339-48. [PMID: 21624403 DOI: 10.1016/j.neures.2011.05.008] [Cited by in Crossref: 109] [Cited by in F6Publishing: 95] [Article Influence: 9.9] [Reference Citation Analysis]
297 Yoon YJ, Kim OY, Gho YS. Extracellular vesicles as emerging intercellular communicasomes. BMB Rep 2014;47:531-9. [PMID: 25104400 DOI: 10.5483/bmbrep.2014.47.10.164] [Cited by in Crossref: 123] [Cited by in F6Publishing: 79] [Article Influence: 17.6] [Reference Citation Analysis]
298 Zappulli V, Friis KP, Fitzpatrick Z, Maguire CA, Breakefield XO. Extracellular vesicles and intercellular communication within the nervous system. J Clin Invest 2016;126:1198-207. [PMID: 27035811 DOI: 10.1172/JCI81134] [Cited by in Crossref: 117] [Cited by in F6Publishing: 80] [Article Influence: 19.5] [Reference Citation Analysis]
299 Segura-Ulate I, Yang B, Vargas-Medrano J, Perez RG. FTY720 (Fingolimod) reverses α-synuclein-induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells. Neuropharmacology 2017;117:149-57. [PMID: 28153532 DOI: 10.1016/j.neuropharm.2017.01.028] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 4.0] [Reference Citation Analysis]
300 Dolatshahi M, Pourmirbabaei S, Kamalian A, Ashraf-Ganjouei A, Yaseri M, Aarabi MH. Longitudinal Alterations of Alpha-Synuclein, Amyloid Beta, Total, and Phosphorylated Tau in Cerebrospinal Fluid and Correlations Between Their Changes in Parkinson's Disease. Front Neurol 2018;9:560. [PMID: 30050494 DOI: 10.3389/fneur.2018.00560] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 5.0] [Reference Citation Analysis]
301 Takanashi Y, Kahyo T, Kamamoto S, Zhang H, Chen B, Ping Y, Mizuno K, Kawase A, Koizumi K, Satou M, Funai K, Shiiya N, Setou M. Ubiquitin-like 3 as a new protein-sorting factor for small extracellular vesicles. Cell Struct Funct 2022;47:1-18. [PMID: 35197392 DOI: 10.1247/csf.21078] [Reference Citation Analysis]
302 Ebrahimi-Fakhari D, Cantuti-Castelvetri I, Fan Z, Rockenstein E, Masliah E, Hyman BT, McLean PJ, Unni VK. Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein. J Neurosci 2011;31:14508-20. [PMID: 21994367 DOI: 10.1523/JNEUROSCI.1560-11.2011] [Cited by in Crossref: 233] [Cited by in F6Publishing: 151] [Article Influence: 21.2] [Reference Citation Analysis]
303 Pergande MR, Kang C, George D, Sutter PA, Crocker SJ, Cologna SM, Givogri MI. Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice. Lipids Health Dis 2022;21:32. [PMID: 35351138 DOI: 10.1186/s12944-022-01644-8] [Reference Citation Analysis]
304 Wang P, Li X, Li X, Yang W, Yu S. Blood Plasma of Patients with Parkinson's Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity. Parkinsons Dis 2016;2016:7596482. [PMID: 27965913 DOI: 10.1155/2016/7596482] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
305 Xiao L, Hareendran S, Loh YP. Function of exosomes in neurological disorders and brain tumors. Extracell Vesicles Circ Nucl Acids 2021;2:55-79. [PMID: 34368812 DOI: 10.20517/evcna.2021.04] [Reference Citation Analysis]
306 Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Mol Neurodegener. 2012;7:42. [PMID: 22920859 DOI: 10.1186/1750-1326-7-42] [Cited by in Crossref: 493] [Cited by in F6Publishing: 482] [Article Influence: 49.3] [Reference Citation Analysis]
307 Li D, Li YP, Li YX, Zhu XH, Du XG, Zhou M, Li WB, Deng HY. Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases. Chin Med J (Engl) 2018;131:2216-25. [PMID: 30203797 DOI: 10.4103/0366-6999.240817] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 5.8] [Reference Citation Analysis]
308 Park SM, Kim KS. Proteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson disease. Prion 2013;7:121-6. [PMID: 23154633 DOI: 10.4161/pri.22850] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 1.5] [Reference Citation Analysis]
309 Christensen DP, Ejlerskov P, Rasmussen I, Vilhardt F. Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axis. J Neuroinflammation 2016;13:59. [PMID: 26957005 DOI: 10.1186/s12974-016-0519-5] [Cited by in Crossref: 13] [Cited by in F6Publishing: 15] [Article Influence: 2.2] [Reference Citation Analysis]
310 Hyun CH, Yoon CY, Lee HJ, Lee SJ. LRRK2 as a Potential Genetic Modifier of Synucleinopathies: Interlacing the Two Major Genetic Factors of Parkinson's Disease. Exp Neurobiol 2013;22:249-57. [PMID: 24465140 DOI: 10.5607/en.2013.22.4.249] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 1.3] [Reference Citation Analysis]
311 Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, Pham E, Masliah E, Gage FH, Riek R. In vivo demonstration that alpha-synuclein oligomers are toxic. Proc Natl Acad Sci U S A 2011;108:4194-9. [PMID: 21325059 DOI: 10.1073/pnas.1100976108] [Cited by in Crossref: 895] [Cited by in F6Publishing: 858] [Article Influence: 81.4] [Reference Citation Analysis]
312 Smith L, Schapira AHV. GBA Variants and Parkinson Disease: Mechanisms and Treatments. Cells 2022;11:1261. [DOI: 10.3390/cells11081261] [Reference Citation Analysis]
313 Ye Y. Regulation of protein homeostasis by unconventional protein secretion in mammalian cells. Semin Cell Dev Biol 2018;83:29-35. [PMID: 29549062 DOI: 10.1016/j.semcdb.2018.03.006] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 3.0] [Reference Citation Analysis]
314 Liu C, Qu L, Zhao C, Shou C. Extracellular gamma-synuclein promotes tumor cell motility by activating β1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion. J Exp Clin Cancer Res 2018;37:117. [PMID: 29903032 DOI: 10.1186/s13046-018-0783-6] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
315 Ingelsson M. Alpha-Synuclein Oligomers-Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders. Front Neurosci 2016;10:408. [PMID: 27656123 DOI: 10.3389/fnins.2016.00408] [Cited by in Crossref: 139] [Cited by in F6Publishing: 131] [Article Influence: 23.2] [Reference Citation Analysis]
316 Sugiura A, McLelland GL, Fon EA, McBride HM. A new pathway for mitochondrial quality control: mitochondrial-derived vesicles. EMBO J 2014;33:2142-56. [PMID: 25107473 DOI: 10.15252/embj.201488104] [Cited by in Crossref: 381] [Cited by in F6Publishing: 355] [Article Influence: 47.6] [Reference Citation Analysis]
317 Cascella R, Bigi A, Cremades N, Cecchi C. Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies. Cell Mol Life Sci 2022;79:174. [PMID: 35244787 DOI: 10.1007/s00018-022-04166-9] [Reference Citation Analysis]
318 Thompson AG, Gray E, Heman-Ackah SM, Mäger I, Talbot K, Andaloussi SE, Wood MJ, Turner MR. Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers. Nat Rev Neurol 2016;12:346-57. [PMID: 27174238 DOI: 10.1038/nrneurol.2016.68] [Cited by in Crossref: 154] [Cited by in F6Publishing: 149] [Article Influence: 25.7] [Reference Citation Analysis]
319 Luna E, Luk KC. Bent out of shape: α-Synuclein misfolding and the convergence of pathogenic pathways in Parkinson's disease. FEBS Lett 2015;589:3749-59. [PMID: 26505673 DOI: 10.1016/j.febslet.2015.10.023] [Cited by in Crossref: 38] [Cited by in F6Publishing: 35] [Article Influence: 5.4] [Reference Citation Analysis]
320 Harischandra DS, Ghaisas S, Zenitsky G, Jin H, Kanthasamy A, Anantharam V, Kanthasamy AG. Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation. Front Neurosci 2019;13:654. [PMID: 31293375 DOI: 10.3389/fnins.2019.00654] [Cited by in Crossref: 56] [Cited by in F6Publishing: 51] [Article Influence: 18.7] [Reference Citation Analysis]
321 Laulagnier K, Javalet C, Hemming FJ, Chivet M, Lachenal G, Blot B, Chatellard C, Sadoul R. Amyloid precursor protein products concentrate in a subset of exosomes specifically endocytosed by neurons. Cell Mol Life Sci 2018;75:757-73. [PMID: 28956068 DOI: 10.1007/s00018-017-2664-0] [Cited by in Crossref: 58] [Cited by in F6Publishing: 57] [Article Influence: 11.6] [Reference Citation Analysis]
322 Kujawska M, Jodynis-Liebert J. What is the Evidence That Parkinson's Disease is a Prion Disorder, Which Originates in the Gut? Int J Mol Sci 2018;19:E3573. [PMID: 30424585 DOI: 10.3390/ijms19113573] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 4.3] [Reference Citation Analysis]
323 Íñigo-Marco I, Valencia M, Larrea L, Bugallo R, Martínez-Goikoetxea M, Zuriguel I, Arrasate M. E46K α-synuclein pathological mutation causes cell-autonomous toxicity without altering protein turnover or aggregation. Proc Natl Acad Sci U S A 2017;114:E8274-83. [PMID: 28900007 DOI: 10.1073/pnas.1703420114] [Cited by in Crossref: 25] [Cited by in F6Publishing: 17] [Article Influence: 5.0] [Reference Citation Analysis]
324 Adav SS, Sze SK. Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profiling. Mol Brain 2016;9:92. [PMID: 27809929 DOI: 10.1186/s13041-016-0272-9] [Cited by in Crossref: 24] [Cited by in F6Publishing: 24] [Article Influence: 4.0] [Reference Citation Analysis]
325 You Y, Ikezu T. Emerging roles of extracellular vesicles in neurodegenerative disorders. Neurobiol Dis 2019;130:104512. [PMID: 31229685 DOI: 10.1016/j.nbd.2019.104512] [Cited by in Crossref: 41] [Cited by in F6Publishing: 33] [Article Influence: 13.7] [Reference Citation Analysis]
326 Alvarez-Erviti L, Seow Y, Schapira AH, Gardiner C, Sargent IL, Wood MJ, Cooper JM. Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. Neurobiol Dis. 2011;42:360-367. [PMID: 21303699 DOI: 10.1016/j.nbd.2011.01.029] [Cited by in Crossref: 433] [Cited by in F6Publishing: 414] [Article Influence: 39.4] [Reference Citation Analysis]
327 Ibrahim T, McLaurin J. Protein seeding in Alzheimer’s disease and Parkinson’s disease: Similarities and differences. World J Neurol 2014; 4(4): 23-35 [DOI: 10.5316/wjn.v4.i4.23] [Reference Citation Analysis]
328 Di Pietro C. Exosome-mediated communication in the ovarian follicle. J Assist Reprod Genet 2016;33:303-11. [PMID: 26814471 DOI: 10.1007/s10815-016-0657-9] [Cited by in Crossref: 48] [Cited by in F6Publishing: 50] [Article Influence: 8.0] [Reference Citation Analysis]
329 Jiang TF, Chen SD. Dysfunction of two lysosome degradation pathways of α-synuclein in Parkinson's disease: potential therapeutic targets? Neurosci Bull 2012;28:649-57. [PMID: 22961477 DOI: 10.1007/s12264-012-1263-1] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 0.8] [Reference Citation Analysis]
330 Acosta SA, Tajiri N, de la Pena I, Bastawrous M, Sanberg PR, Kaneko Y, Borlongan CV. Alpha-synuclein as a pathological link between chronic traumatic brain injury and Parkinson's disease. J Cell Physiol 2015;230:1024-32. [PMID: 25251017 DOI: 10.1002/jcp.24830] [Cited by in Crossref: 76] [Cited by in F6Publishing: 73] [Article Influence: 10.9] [Reference Citation Analysis]
331 Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A. Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. Mol Neurodegener 2012;7:38. [PMID: 22892036 DOI: 10.1186/1750-1326-7-38] [Cited by in Crossref: 75] [Cited by in F6Publishing: 71] [Article Influence: 7.5] [Reference Citation Analysis]
332 Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200:373-383. [PMID: 23420871 DOI: 10.1083/jcb.201211138] [Cited by in Crossref: 4005] [Cited by in F6Publishing: 3878] [Article Influence: 445.0] [Reference Citation Analysis]
333 Dolcetti E, Bruno A, Guadalupi L, Rizzo FR, Musella A, Gentile A, De Vito F, Caioli S, Bullitta S, Fresegna D, Vanni V, Balletta S, Sanna K, Buttari F, Stampanoni Bassi M, Centonze D, Mandolesi G. Emerging Role of Extracellular Vesicles in the Pathophysiology of Multiple Sclerosis. Int J Mol Sci 2020;21:E7336. [PMID: 33020408 DOI: 10.3390/ijms21197336] [Cited by in Crossref: 11] [Cited by in F6Publishing: 14] [Article Influence: 5.5] [Reference Citation Analysis]
334 Valdinocci D, Radford RAW, Goulding M, Hayashi J, Chung RS, Pountney DL. Extracellular Interactions of Alpha-Synuclein in Multiple System Atrophy. Int J Mol Sci 2018;19:E4129. [PMID: 30572656 DOI: 10.3390/ijms19124129] [Cited by in Crossref: 13] [Cited by in F6Publishing: 10] [Article Influence: 3.3] [Reference Citation Analysis]
335 Mkrtchian S, Ebberyd A, Veerman RE, Méndez-lago M, Gabrielsson S, Eriksson LI, Gómez-galán M. Surgical Trauma in Mice Modifies the Content of Circulating Extracellular Vesicles. Front Immunol 2022;12:824696. [DOI: 10.3389/fimmu.2021.824696] [Reference Citation Analysis]
336 Di Marco Vieira B, Radford RAW, Hayashi J, Eaton ED, Greenaway B, Jambas M, Petcu EB, Chung RS, Pountney DL. Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes. Life (Basel) 2020;10:E183. [PMID: 32911644 DOI: 10.3390/life10090183] [Cited by in Crossref: 2] [Article Influence: 1.0] [Reference Citation Analysis]
337 Shim KH, Go HG, Bae H, Jeong DE, Kim D, Youn YC, Kim S, An SSA, Kang MJ. Decreased Exosomal Acetylcholinesterase Activity in the Plasma of Patients With Parkinson's Disease. Front Aging Neurosci 2021;13:665400. [PMID: 34122043 DOI: 10.3389/fnagi.2021.665400] [Reference Citation Analysis]
338 Basso M, Pozzi S, Tortarolo M, Fiordaliso F, Bisighini C, Pasetto L, Spaltro G, Lidonnici D, Gensano F, Battaglia E, Bendotti C, Bonetto V. Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis. J Biol Chem 2013;288:15699-711. [PMID: 23592792 DOI: 10.1074/jbc.M112.425066] [Cited by in Crossref: 140] [Cited by in F6Publishing: 91] [Article Influence: 15.6] [Reference Citation Analysis]
339 Zhu X, Hollinger KR, Huang Y, Borjabad A, Kim B, Arab T, Thomas AG, Moniruzzaman M, Lovell L, Turchinovich A, Witwer KW, Volsky DJ, Haughey NJ, Slusher BS. Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV. Neurobiology of Disease 2022;169:105734. [DOI: 10.1016/j.nbd.2022.105734] [Reference Citation Analysis]
340 Chakrabarti R, Wichmann C. Nanomachinery Organizing Release at Neuronal and Ribbon Synapses. Int J Mol Sci 2019;20:E2147. [PMID: 31052288 DOI: 10.3390/ijms20092147] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 1.7] [Reference Citation Analysis]
341 Klann EM, Dissanayake U, Gurrala A, Farrer M, Shukla AW, Ramirez-zamora A, Mai V, Vedam-mai V. The Gut–Brain Axis and Its Relation to Parkinson’s Disease: A Review. Front Aging Neurosci 2022;13:782082. [DOI: 10.3389/fnagi.2021.782082] [Reference Citation Analysis]
342 Chen Y, Zhao Y, Yin Y, Jia X, Mao L. Mechanism of cargo sorting into small extracellular vesicles. Bioengineered 2021;12:8186-201. [PMID: 34661500 DOI: 10.1080/21655979.2021.1977767] [Reference Citation Analysis]
343 Toni M, Massimino ML, De Mario A, Angiulli E, Spisni E. Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach. Front Neurosci 2017;11:3. [PMID: 28154522 DOI: 10.3389/fnins.2017.00003] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 4.2] [Reference Citation Analysis]
344 Vassileff N, Vella LJ, Rajapaksha H, Shambrook M, Kenari AN, McLean C, Hill AF, Cheng L. Revealing the Proteome of Motor Cortex Derived Extracellular Vesicles Isolated from Amyotrophic Lateral Sclerosis Human Postmortem Tissues. Cells 2020;9:E1709. [PMID: 32708779 DOI: 10.3390/cells9071709] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
345 Brandel JP, Corbillé AG, Derkinderen P, Haïk S. [Is Parkinson's disease a prion disease?]. Rev Neurol (Paris) 2015;171:812-24. [PMID: 26563663 DOI: 10.1016/j.neurol.2015.10.005] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.7] [Reference Citation Analysis]
346 Minakaki G, Krainc D, Burbulla LF. The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson's Disease. Front Cell Dev Biol 2020;8:580634. [PMID: 33381501 DOI: 10.3389/fcell.2020.580634] [Cited by in Crossref: 7] [Cited by in F6Publishing: 3] [Article Influence: 3.5] [Reference Citation Analysis]
347 Burré J, Sharma M, Südhof TC. Cell Biology and Pathophysiology of α-Synuclein. Cold Spring Harb Perspect Med 2018;8:a024091. [PMID: 28108534 DOI: 10.1101/cshperspect.a024091] [Cited by in Crossref: 114] [Cited by in F6Publishing: 111] [Article Influence: 28.5] [Reference Citation Analysis]
348 Gangoda L, Boukouris S, Liem M, Kalra H, Mathivanan S. Extracellular vesicles including exosomes are mediators of signal transduction: are they protective or pathogenic? Proteomics 2015;15:260-71. [PMID: 25307053 DOI: 10.1002/pmic.201400234] [Cited by in Crossref: 143] [Cited by in F6Publishing: 142] [Article Influence: 17.9] [Reference Citation Analysis]
349 Eitan E, Suire C, Zhang S, Mattson MP. Impact of lysosome status on extracellular vesicle content and release. Ageing Res Rev 2016;32:65-74. [PMID: 27238186 DOI: 10.1016/j.arr.2016.05.001] [Cited by in Crossref: 106] [Cited by in F6Publishing: 107] [Article Influence: 17.7] [Reference Citation Analysis]
350 Espargaró A, Busquets MA, Estelrich J, Sabate R. Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal Invasion. Front Mol Neurosci 2016;9:29. [PMID: 27147962 DOI: 10.3389/fnmol.2016.00029] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 2.0] [Reference Citation Analysis]
351 Stuendl A, Kunadt M, Kruse N, Bartels C, Moebius W, Danzer KM, Mollenhauer B, Schneider A. Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain 2016;139:481-94. [PMID: 26647156 DOI: 10.1093/brain/awv346] [Cited by in Crossref: 217] [Cited by in F6Publishing: 206] [Article Influence: 31.0] [Reference Citation Analysis]
352 Emmer KL, Waxman EA, Covy JP, Giasson BI. E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment. J Biol Chem 2011;286:35104-18. [PMID: 21846727 DOI: 10.1074/jbc.M111.247965] [Cited by in Crossref: 87] [Cited by in F6Publishing: 63] [Article Influence: 7.9] [Reference Citation Analysis]
353 Aulić S, Masperone L, Narkiewicz J, Isopi E, Bistaffa E, Ambrosetti E, Pastore B, De Cecco E, Scaini D, Zago P, Moda F, Tagliavini F, Legname G. α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication. Sci Rep 2017;7:10050. [PMID: 28855681 DOI: 10.1038/s41598-017-10236-x] [Cited by in Crossref: 62] [Cited by in F6Publishing: 61] [Article Influence: 12.4] [Reference Citation Analysis]
354 Daniele SG, Béraud D, Davenport C, Cheng K, Yin H, Maguire-Zeiss KA. Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders. Sci Signal 2015;8:ra45. [PMID: 25969543 DOI: 10.1126/scisignal.2005965] [Cited by in Crossref: 132] [Cited by in F6Publishing: 125] [Article Influence: 18.9] [Reference Citation Analysis]
355 Gagliardi D, Bresolin N, Comi GP, Corti S. Extracellular vesicles and amyotrophic lateral sclerosis: from misfolded protein vehicles to promising clinical biomarkers. Cell Mol Life Sci 2021;78:561-72. [PMID: 32803397 DOI: 10.1007/s00018-020-03619-3] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
356 Tittelmeier J, Nachman E, Nussbaum-Krammer C. Molecular Chaperones: A Double-Edged Sword in Neurodegenerative Diseases. Front Aging Neurosci 2020;12:581374. [PMID: 33132902 DOI: 10.3389/fnagi.2020.581374] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 2.5] [Reference Citation Analysis]
357 Pei Y, Maitta RW. Alpha synuclein in hematopoiesis and immunity. Heliyon 2019;5:e02590. [PMID: 31692680 DOI: 10.1016/j.heliyon.2019.e02590] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 3.3] [Reference Citation Analysis]
358 Breda C, Nugent ML, Estranero JG, Kyriacou CP, Outeiro TF, Steinert JR, Giorgini F. Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour. Hum Mol Genet 2015;24:1077-91. [PMID: 25305083 DOI: 10.1093/hmg/ddu521] [Cited by in Crossref: 65] [Cited by in F6Publishing: 61] [Article Influence: 8.1] [Reference Citation Analysis]
359 Sheehan P, Waites CL. Coordination of synaptic vesicle trafficking and turnover by the Rab35 signaling network. Small GTPases 2019;10:54-63. [PMID: 28129039 DOI: 10.1080/21541248.2016.1270392] [Cited by in Crossref: 15] [Cited by in F6Publishing: 12] [Article Influence: 3.0] [Reference Citation Analysis]
360 Sacino AN, Giasson BI. Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology? Alzheimers Res Ther 2012;4:48. [PMID: 23245350 DOI: 10.1186/alzrt151] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
361 Chivet M, Hemming F, Pernet-Gallay K, Fraboulet S, Sadoul R. Emerging role of neuronal exosomes in the central nervous system. Front Physiol 2012;3:145. [PMID: 22654762 DOI: 10.3389/fphys.2012.00145] [Cited by in Crossref: 131] [Cited by in F6Publishing: 129] [Article Influence: 13.1] [Reference Citation Analysis]
362 Klyubin I, Cullen WK, Hu NW, Rowan MJ. Alzheimer's disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory. Mol Brain 2012;5:25. [PMID: 22805374 DOI: 10.1186/1756-6606-5-25] [Cited by in Crossref: 62] [Cited by in F6Publishing: 64] [Article Influence: 6.2] [Reference Citation Analysis]
363 Béraud D, Twomey M, Bloom B, Mittereder A, Ton V, Neitzke K, Chasovskikh S, Mhyre TR, Maguire-Zeiss KA. α-Synuclein Alters Toll-Like Receptor Expression. Front Neurosci 2011;5:80. [PMID: 21747756 DOI: 10.3389/fnins.2011.00080] [Cited by in Crossref: 106] [Cited by in F6Publishing: 102] [Article Influence: 9.6] [Reference Citation Analysis]
364 Schiera G, Di Liegro CM, Di Liegro I. Cell-to-Cell Communication in Learning and Memory: From Neuro- and Glio-Transmission to Information Exchange Mediated by Extracellular Vesicles. Int J Mol Sci 2019;21:E266. [PMID: 31906013 DOI: 10.3390/ijms21010266] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 4.0] [Reference Citation Analysis]
365 Stefanis L. α-Synuclein in Parkinson's disease. Cold Spring Harb Perspect Med 2012;2:a009399. [PMID: 22355802 DOI: 10.1101/cshperspect.a009399] [Cited by in Crossref: 482] [Cited by in F6Publishing: 450] [Article Influence: 53.6] [Reference Citation Analysis]
366 Cardinale A, Calabrese V, de Iure A, Picconi B. Alpha-Synuclein as a Prominent Actor in the Inflammatory Synaptopathy of Parkinson's Disease. Int J Mol Sci 2021;22:6517. [PMID: 34204581 DOI: 10.3390/ijms22126517] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
367 Dexter E, Kong Q. Neuroprotective effect and potential of cellular prion protein and its cleavage products for treatment of neurodegenerative disorders part I. a literature review. Expert Rev Neurother 2021;21:969-82. [PMID: 34470561 DOI: 10.1080/14737175.2021.1965881] [Reference Citation Analysis]
368 Sandhof CA, Hoppe SO, Tittelmeier J, Nussbaum-Krammer C. C. elegans Models to Study the Propagation of Prions and Prion-Like Proteins. Biomolecules 2020;10:E1188. [PMID: 32824215 DOI: 10.3390/biom10081188] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
369 Sorrentino ZA, Giasson BI, Chakrabarty P. α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease. Acta Neuropathol 2019;138:1-21. [PMID: 30798354 DOI: 10.1007/s00401-019-01977-2] [Cited by in Crossref: 43] [Cited by in F6Publishing: 39] [Article Influence: 14.3] [Reference Citation Analysis]
370 Sanders DW, Kaufman SK, Holmes BB, Diamond MI. Prions and Protein Assemblies that Convey Biological Information in Health and Disease. Neuron 2016;89:433-48. [PMID: 26844828 DOI: 10.1016/j.neuron.2016.01.026] [Cited by in Crossref: 50] [Cited by in F6Publishing: 45] [Article Influence: 8.3] [Reference Citation Analysis]
371 Melnik BC. Synergistic Effects of Milk-Derived Exosomes and Galactose on α-Synuclein Pathology in Parkinson's Disease and Type 2 Diabetes Mellitus. Int J Mol Sci 2021;22:1059. [PMID: 33494388 DOI: 10.3390/ijms22031059] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
372 Fellner L, Jellinger KA, Wenning GK, Stefanova N. Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts. Acta Neuropathol 2011;121:675-93. [PMID: 21562886 DOI: 10.1007/s00401-011-0833-z] [Cited by in Crossref: 128] [Cited by in F6Publishing: 124] [Article Influence: 11.6] [Reference Citation Analysis]
373 Gamage TKJB, Fraser M. The Role of Extracellular Vesicles in the Developing Brain: Current Perspective and Promising Source of Biomarkers and Therapy for Perinatal Brain Injury. Front Neurosci 2021;15:744840. [PMID: 34630028 DOI: 10.3389/fnins.2021.744840] [Reference Citation Analysis]
374 Song P, Trajkovic K, Tsunemi T, Krainc D. Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway. J Neurosci 2016;36:2425-37. [PMID: 26911690 DOI: 10.1523/JNEUROSCI.2569-15.2016] [Cited by in Crossref: 79] [Cited by in F6Publishing: 54] [Article Influence: 13.2] [Reference Citation Analysis]
375 Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF. Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J Biol Chem 2012;287:3842-9. [PMID: 22057275 DOI: 10.1074/jbc.M111.277061] [Cited by in Crossref: 556] [Cited by in F6Publishing: 375] [Article Influence: 50.5] [Reference Citation Analysis]
376 Lima LMTR, Sisnande T. Nutrient-sensing amyloid metastasis. Biofactors 2022. [PMID: 35128738 DOI: 10.1002/biof.1825] [Reference Citation Analysis]
377 West A, Brummel BE, Braun AR, Rhoades E, Sachs JN. Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein. Biochim Biophys Acta 2016;1858:1594-609. [PMID: 26972046 DOI: 10.1016/j.bbamem.2016.03.012] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 5.2] [Reference Citation Analysis]
378 Allen Reish HE, Standaert DG. Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease. J Parkinsons Dis 2015;5:1-19. [PMID: 25588354 DOI: 10.3233/JPD-140491] [Cited by in Crossref: 87] [Cited by in F6Publishing: 67] [Article Influence: 12.4] [Reference Citation Analysis]
379 Steiner JA, Angot E, Brundin P. A deadly spread: cellular mechanisms of α-synuclein transfer. Cell Death Differ 2011;18:1425-33. [PMID: 21566660 DOI: 10.1038/cdd.2011.53] [Cited by in Crossref: 89] [Cited by in F6Publishing: 89] [Article Influence: 8.1] [Reference Citation Analysis]
380 Sitia R, Rubartelli A. Evolution, role in inflammation, and redox control of leaderless secretory proteins. J Biol Chem 2020;295:7799-811. [PMID: 32332096 DOI: 10.1074/jbc.REV119.008907] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 6.0] [Reference Citation Analysis]
381 Couceiro JR, Gallardo R, De Smet F, De Baets G, Baatsen P, Annaert W, Roose K, Saelens X, Schymkowitz J, Rousseau F. Sequence-dependent internalization of aggregating peptides. J Biol Chem 2015;290:242-58. [PMID: 25391649 DOI: 10.1074/jbc.M114.586636] [Cited by in Crossref: 17] [Cited by in F6Publishing: 11] [Article Influence: 2.1] [Reference Citation Analysis]
382 Yuyama K, Takahashi K, Usuki S, Mikami D, Sun H, Hanamatsu H, Furukawa J, Mukai K, Igarashi Y. Plant sphingolipids promote extracellular vesicle release and alleviate amyloid-β pathologies in a mouse model of Alzheimer's disease. Sci Rep 2019;9:16827. [PMID: 31727994 DOI: 10.1038/s41598-019-53394-w] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 3.0] [Reference Citation Analysis]
383 Tofaris GK, Goedert M, Spillantini MG. The Transcellular Propagation and Intracellular Trafficking of α-Synuclein. Cold Spring Harb Perspect Med 2017;7:a024380. [PMID: 27920026 DOI: 10.1101/cshperspect.a024380] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 3.2] [Reference Citation Analysis]
384 Lim J, Yue Z. Neuronal aggregates: formation, clearance, and spreading. Dev Cell 2015;32:491-501. [PMID: 25710535 DOI: 10.1016/j.devcel.2015.02.002] [Cited by in Crossref: 126] [Cited by in F6Publishing: 115] [Article Influence: 18.0] [Reference Citation Analysis]
385 Edgar JR. Q&A: What are exosomes, exactly? BMC Biol 2016;14:46. [PMID: 27296830 DOI: 10.1186/s12915-016-0268-z] [Cited by in Crossref: 147] [Cited by in F6Publishing: 130] [Article Influence: 24.5] [Reference Citation Analysis]
386 Oueslati A, Ximerakis M, Vekrellis K. Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like Propagation. Exp Neurobiol 2014;23:324-36. [PMID: 25548532 DOI: 10.5607/en.2014.23.4.324] [Cited by in Crossref: 33] [Cited by in F6Publishing: 30] [Article Influence: 4.1] [Reference Citation Analysis]
387 Kim KM, Abdelmohsen K, Mustapic M, Kapogiannis D, Gorospe M. RNA in extracellular vesicles. Wiley Interdiscip Rev RNA. 2017;8. [PMID: 28130830 DOI: 10.1002/wrna.1413] [Cited by in Crossref: 173] [Cited by in F6Publishing: 177] [Article Influence: 34.6] [Reference Citation Analysis]
388 Dutta S, Hornung S, Kruayatidee A, Maina KN, Del Rosario I, Paul KC, Wong DY, Duarte Folle A, Markovic D, Palma JA, Serrano GE, Adler CH, Perlman SL, Poon WW, Kang UJ, Alcalay RN, Sklerov M, Gylys KH, Kaufmann H, Fogel BL, Bronstein JM, Ritz B, Bitan G. α-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson's disease from multiple system atrophy. Acta Neuropathol 2021;142:495-511. [PMID: 33991233 DOI: 10.1007/s00401-021-02324-0] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
389 Obergasteiger J, Frapporti G, Pramstaller PP, Hicks AA, Volta M. A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics. Mol Neurodegener. 2018;13:40. [PMID: 30071902 DOI: 10.1186/s13024-018-0273-5] [Cited by in Crossref: 37] [Cited by in F6Publishing: 35] [Article Influence: 9.3] [Reference Citation Analysis]
390 Emmanouilidou E, Elenis D, Papasilekas T, Stranjalis G, Gerozissis K, Ioannou PC, Vekrellis K. Assessment of α-synuclein secretion in mouse and human brain parenchyma. PLoS One 2011;6:e22225. [PMID: 21779395 DOI: 10.1371/journal.pone.0022225] [Cited by in Crossref: 99] [Cited by in F6Publishing: 102] [Article Influence: 9.0] [Reference Citation Analysis]
391 Longobardi A, Benussi L, Nicsanu R, Bellini S, Ferrari C, Saraceno C, Zanardini R, Catania M, Di Fede G, Squitti R, Binetti G, Ghidoni R. Plasma Extracellular Vesicle Size and Concentration Are Altered in Alzheimer's Disease, Dementia With Lewy Bodies, and Frontotemporal Dementia. Front Cell Dev Biol 2021;9:667369. [PMID: 34046409 DOI: 10.3389/fcell.2021.667369] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
392 Béraud D, Hathaway HA, Trecki J, Chasovskikh S, Johnson DA, Johnson JA, Federoff HJ, Shimoji M, Mhyre TR, Maguire-Zeiss KA. Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein. J Neuroimmune Pharmacol 2013;8:94-117. [PMID: 23054368 DOI: 10.1007/s11481-012-9401-0] [Cited by in Crossref: 107] [Cited by in F6Publishing: 104] [Article Influence: 10.7] [Reference Citation Analysis]
393 Basso M, Bonetto V. Extracellular Vesicles and a Novel Form of Communication in the Brain. Front Neurosci 2016;10:127. [PMID: 27065789 DOI: 10.3389/fnins.2016.00127] [Cited by in Crossref: 89] [Cited by in F6Publishing: 89] [Article Influence: 14.8] [Reference Citation Analysis]
394 Gaspar R, Pallbo J, Weininger U, Linse S, Sparr E. Ganglioside lipids accelerate α-synuclein amyloid formation. Biochim Biophys Acta Proteins Proteom 2018:S1570-9639(18)30116-X. [PMID: 30077783 DOI: 10.1016/j.bbapap.2018.07.004] [Cited by in Crossref: 30] [Cited by in F6Publishing: 26] [Article Influence: 7.5] [Reference Citation Analysis]
395 Wilkaniec A, Lenkiewicz AM, Czapski GA, Jęśko HM, Hilgier W, Brodzik R, Gąssowska-Dobrowolska M, Culmsee C, Adamczyk A. Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson's Disease Etiopathology. Mol Neurobiol 2019;56:125-40. [PMID: 29681024 DOI: 10.1007/s12035-018-1082-0] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 5.3] [Reference Citation Analysis]
396 Marković I, Kresojević N, Kostić VS. Glucocerebrosidase and parkinsonism: lessons to learn. J Neurol 2016;263:1033-44. [PMID: 26995357 DOI: 10.1007/s00415-016-8085-4] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
397 Ejlerskov P, Rasmussen I, Nielsen TT, Bergström AL, Tohyama Y, Jensen PH, Vilhardt F. Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion. J Biol Chem 2013;288:17313-35. [PMID: 23629650 DOI: 10.1074/jbc.M112.401174] [Cited by in Crossref: 135] [Cited by in F6Publishing: 93] [Article Influence: 15.0] [Reference Citation Analysis]
398 Leite K, Garg P, Spitzner FP, Guerin Darvas S, Bähr M, Priesemann V, Kügler S. α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals. Front Mol Neurosci 2022;15:868790. [DOI: 10.3389/fnmol.2022.868790] [Reference Citation Analysis]
399 Golde TE, Borchelt DR, Giasson BI, Lewis J. Thinking laterally about neurodegenerative proteinopathies. J Clin Invest 2013;123:1847-55. [PMID: 23635781 DOI: 10.1172/JCI66029] [Cited by in Crossref: 71] [Cited by in F6Publishing: 44] [Article Influence: 7.9] [Reference Citation Analysis]
400 Witt SN. Molecular chaperones, α-synuclein, and neurodegeneration. Mol Neurobiol 2013;47:552-60. [PMID: 22923346 DOI: 10.1007/s12035-012-8325-2] [Cited by in Crossref: 31] [Cited by in F6Publishing: 32] [Article Influence: 3.1] [Reference Citation Analysis]
401 Gustafsson G, Lööv C, Persson E, Lázaro DF, Takeda S, Bergström J, Erlandsson A, Sehlin D, Balaj L, György B, Hallbeck M, Outeiro TF, Breakefield XO, Hyman BT, Ingelsson M. Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells. Cell Mol Neurobiol 2018;38:1539-50. [PMID: 30288631 DOI: 10.1007/s10571-018-0622-5] [Cited by in Crossref: 35] [Cited by in F6Publishing: 27] [Article Influence: 8.8] [Reference Citation Analysis]
402 Yamada J, Jinno S. Promotion of synaptogenesis and neural circuit development by exosomes. Ann Transl Med 2019;7:S323. [PMID: 32016041 DOI: 10.21037/atm.2019.09.154] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
403 Luo HT, Zhang JP, Miao F. Effects of pramipexole treatment on the α-synuclein content in serum exosomes of Parkinson's disease patients. Exp Ther Med 2016;12:1373-6. [PMID: 27588058 DOI: 10.3892/etm.2016.3471] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
404 Hall GF, Patuto BA. Is tau ready for admission to the prion club? Prion 2012;6:223-33. [PMID: 22561167 DOI: 10.4161/pri.19912] [Cited by in Crossref: 25] [Cited by in F6Publishing: 29] [Article Influence: 2.5] [Reference Citation Analysis]
405 Wang R, Sun H, Ren H, Wang G. α-Synuclein aggregation and transmission in Parkinson's disease: a link to mitochondria and lysosome. Sci China Life Sci 2020;63:1850-9. [PMID: 32681494 DOI: 10.1007/s11427-020-1756-9] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 2.5] [Reference Citation Analysis]
406 Gerson JE, Kayed R. Formation and propagation of tau oligomeric seeds. Front Neurol. 2013;4:93. [PMID: 23882255 DOI: 10.3389/fneur.2013.00093] [Cited by in Crossref: 62] [Cited by in F6Publishing: 70] [Article Influence: 6.9] [Reference Citation Analysis]
407 Ugalde CL, Gordon SE, Shambrook M, Nasiri Kenari A, Coleman BM, Perugini MA, Lawson VA, Finkelstein DI, Hill AF. An intact membrane is essential for small extracellular vesicle-induced modulation of α-synuclein fibrillization. J Extracell Vesicles 2020;10:e12034. [PMID: 33318779 DOI: 10.1002/jev2.12034] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
408 Recasens A, Dehay B. Alpha-synuclein spreading in Parkinson's disease. Front Neuroanat 2014;8:159. [PMID: 25565982 DOI: 10.3389/fnana.2014.00159] [Cited by in Crossref: 107] [Cited by in F6Publishing: 94] [Article Influence: 13.4] [Reference Citation Analysis]
409 Delenclos M, Trendafilova T, Jones DR, Moussaud S, Baine AM, Yue M, Hirst WD, McLean PJ. A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo. Front Neurosci 2015;9:511. [PMID: 26834539 DOI: 10.3389/fnins.2015.00511] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
410 Hijaz BA, Volpicelli-Daley LA. Initiation and propagation of α-synuclein aggregation in the nervous system. Mol Neurodegener 2020;15:19. [PMID: 32143659 DOI: 10.1186/s13024-020-00368-6] [Cited by in Crossref: 42] [Cited by in F6Publishing: 49] [Article Influence: 21.0] [Reference Citation Analysis]
411 Correll VL, Otto JJ, Risi CM, Main BP, Boutros PC, Kislinger T, Galkin VE, Nyalwidhe JO, Semmes OJ, Yang L. Optimization of small extracellular vesicle isolation from expressed prostatic secretions in urine for in-depth proteomic analysis. J Extracell Vesicles 2022;11:e12184. [PMID: 35119778 DOI: 10.1002/jev2.12184] [Reference Citation Analysis]
412 Candelario KM, Steindler DA. The role of extracellular vesicles in the progression of neurodegenerative disease and cancer. Trends Mol Med 2014;20:368-74. [PMID: 24835084 DOI: 10.1016/j.molmed.2014.04.003] [Cited by in Crossref: 62] [Cited by in F6Publishing: 57] [Article Influence: 7.8] [Reference Citation Analysis]
413 Lee MJ, Park DH, Kang JH. Exosomes as the source of biomarkers of metabolic diseases. Ann Pediatr Endocrinol Metab 2016;21:119-25. [PMID: 27777903 DOI: 10.6065/apem.2016.21.3.119] [Cited by in Crossref: 32] [Cited by in F6Publishing: 30] [Article Influence: 5.3] [Reference Citation Analysis]
414 Azizi F, Askari S, Javadpour P, Hadjighassem M, Ghasemi R. Potential role of exosome in post-stroke reorganization and/or neurodegeneration. EXCLI J 2020;19:1590-606. [PMID: 33408596 DOI: 10.17179/excli2020-3025] [Reference Citation Analysis]
415 Kwakye GF, McMinimy RA, Aschner M. Disease-Toxicant Interactions in Parkinson's Disease Neuropathology. Neurochem Res 2017;42:1772-86. [PMID: 27613618 DOI: 10.1007/s11064-016-2052-4] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 1.7] [Reference Citation Analysis]
416 Alvarez-Castelao B, Gorostidi A, Ruíz-Martínez J, López de Munain A, Castaño JG. Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls. Front Aging Neurosci 2014;6:169. [PMID: 25076905 DOI: 10.3389/fnagi.2014.00169] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
417 de Pablos Torró LM, Retana Moreira L, Osuna A. Extracellular Vesicles in Chagas Disease: A New Passenger for an Old Disease. Front Microbiol 2018;9:1190. [PMID: 29910793 DOI: 10.3389/fmicb.2018.01190] [Cited by in Crossref: 18] [Cited by in F6Publishing: 14] [Article Influence: 4.5] [Reference Citation Analysis]
418 Sandhof CA, Hoppe SO, Druffel-Augustin S, Gallrein C, Kirstein J, Voisine C, Nussbaum-Krammer C. Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. Autophagy 2020;16:878-99. [PMID: 31354022 DOI: 10.1080/15548627.2019.1643657] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 3.3] [Reference Citation Analysis]
419 Rietdijk CD, Perez-Pardo P, Garssen J, van Wezel RJ, Kraneveld AD. Exploring Braak's Hypothesis of Parkinson's Disease. Front Neurol 2017;8:37. [PMID: 28243222 DOI: 10.3389/fneur.2017.00037] [Cited by in Crossref: 99] [Cited by in F6Publishing: 87] [Article Influence: 19.8] [Reference Citation Analysis]
420 Bellani S, Mescola A, Ronzitti G, Tsushima H, Tilve S, Canale C, Valtorta F, Chieregatti E. GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein. Cell Death Differ 2014;21:1971-83. [PMID: 25124556 DOI: 10.1038/cdd.2014.111] [Cited by in Crossref: 41] [Cited by in F6Publishing: 40] [Article Influence: 5.1] [Reference Citation Analysis]
421 Schapansky J, Nardozzi JD, LaVoie MJ. The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease. Neuroscience 2015;302:74-88. [PMID: 25284317 DOI: 10.1016/j.neuroscience.2014.09.049] [Cited by in Crossref: 80] [Cited by in F6Publishing: 70] [Article Influence: 10.0] [Reference Citation Analysis]
422 López-Guerrero JA, Ripa I, Andreu S, Bello-Morales R. The Role of Extracellular Vesicles in Demyelination of the Central Nervous System. Int J Mol Sci 2020;21:E9111. [PMID: 33266211 DOI: 10.3390/ijms21239111] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
423 Emmanouilidou E, Vekrellis K. Exocytosis and Spreading of Normal and Aberrant α-Synuclein. Brain Pathol 2016;26:398-403. [PMID: 26940375 DOI: 10.1111/bpa.12373] [Cited by in Crossref: 38] [Cited by in F6Publishing: 40] [Article Influence: 9.5] [Reference Citation Analysis]
424 Zhang Q, Kim YC, Narayanan NS. Disease-modifying therapeutic directions for Lewy-Body dementias. Front Neurosci 2015;9:293. [PMID: 26347604 DOI: 10.3389/fnins.2015.00293] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 1.6] [Reference Citation Analysis]
425 Emanuele M, Chieregatti E. Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous role. Biomolecules 2015;5:865-92. [PMID: 25985082 DOI: 10.3390/biom5020865] [Cited by in Crossref: 27] [Cited by in F6Publishing: 25] [Article Influence: 3.9] [Reference Citation Analysis]
426 Gegg ME, Verona G, Schapira AHV. Glucocerebrosidase deficiency promotes release of α-synuclein fibrils from cultured neurons. Hum Mol Genet 2020;29:1716-28. [PMID: 32391886 DOI: 10.1093/hmg/ddaa085] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 9.0] [Reference Citation Analysis]
427 Song X, Ding Y, Liu G, Yang X, Zhao R, Zhang Y, Zhao X, Anderson GJ, Nie G. Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases. J Biol Chem 2016;291:8453-64. [PMID: 26895960 DOI: 10.1074/jbc.M116.716316] [Cited by in Crossref: 51] [Cited by in F6Publishing: 35] [Article Influence: 8.5] [Reference Citation Analysis]
428 Hoshino A, Helwig M, Rezaei S, Berridge C, Eriksen JL, Lindberg I. A novel function for proSAAS as an amyloid anti-aggregant in Alzheimer's disease. J Neurochem 2014;128:419-30. [PMID: 24102330 DOI: 10.1111/jnc.12454] [Cited by in Crossref: 24] [Cited by in F6Publishing: 22] [Article Influence: 2.7] [Reference Citation Analysis]
429 Hamlett ED, LaRosa A, Mufson EJ, Fortea J, Ledreux A, Granholm AC. Exosome release and cargo in Down syndrome. Dev Neurobiol 2019;79:639-55. [PMID: 31347291 DOI: 10.1002/dneu.22712] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 3.3] [Reference Citation Analysis]
430 Cerri S, Ghezzi C, Sampieri M, Siani F, Avenali M, Dornini G, Zangaglia R, Minafra B, Blandini F. The Exosomal/Total α-Synuclein Ratio in Plasma Is Associated With Glucocerebrosidase Activity and Correlates With Measures of Disease Severity in PD Patients. Front Cell Neurosci 2018;12:125. [PMID: 29867358 DOI: 10.3389/fncel.2018.00125] [Cited by in Crossref: 37] [Cited by in F6Publishing: 35] [Article Influence: 9.3] [Reference Citation Analysis]
431 Barreto BR, D'Acunzo P, Ungania JM, Das S, Hashim A, Goulbourne CN, Canals-Baker S, Saito M, Saito M, Sershen H, Levy E. Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner. Neurochem Res 2022. [PMID: 35501523 DOI: 10.1007/s11064-022-03612-1] [Reference Citation Analysis]
432 Ferreira SA, Romero-Ramos M. Microglia Response During Parkinson's Disease: Alpha-Synuclein Intervention. Front Cell Neurosci 2018;12:247. [PMID: 30127724 DOI: 10.3389/fncel.2018.00247] [Cited by in Crossref: 75] [Cited by in F6Publishing: 67] [Article Influence: 18.8] [Reference Citation Analysis]
433 Tatullo M, Codispoti B, Spagnuolo G, Zavan B. Human Periapical Cyst-Derived Stem Cells Can Be A Smart "Lab-on-A-Cell" to Investigate Neurodegenerative Diseases and the Related Alteration of the Exosomes' Content. Brain Sci 2019;9:E358. [PMID: 31817546 DOI: 10.3390/brainsci9120358] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
434 Ardiles AO, Grabrucker AM, Scholl FG, Rudenko G, Borsello T. Molecular and Cellular Mechanisms of Synaptopathies. Neural Plast 2017;2017:2643943. [PMID: 28540088 DOI: 10.1155/2017/2643943] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
435 Trajkovic K, Jeong H, Krainc D. Mutant Huntingtin Is Secreted via a Late Endosomal/Lysosomal Unconventional Secretory Pathway. J Neurosci 2017;37:9000-12. [PMID: 28821645 DOI: 10.1523/JNEUROSCI.0118-17.2017] [Cited by in Crossref: 37] [Cited by in F6Publishing: 25] [Article Influence: 7.4] [Reference Citation Analysis]
436 Rosa-Fernandes L, Rocha VB, Carregari VC, Urbani A, Palmisano G. A Perspective on Extracellular Vesicles Proteomics. Front Chem 2017;5:102. [PMID: 29209607 DOI: 10.3389/fchem.2017.00102] [Cited by in Crossref: 56] [Cited by in F6Publishing: 52] [Article Influence: 11.2] [Reference Citation Analysis]
437 Shi M, Liu C, Cook TJ, Bullock KM, Zhao Y, Ginghina C, Li Y, Aro P, Dator R, He C, Hipp MJ, Zabetian CP, Peskind ER, Hu SC, Quinn JF, Galasko DR, Banks WA, Zhang J. Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease. Acta Neuropathol 2014;128:639-50. [PMID: 24997849 DOI: 10.1007/s00401-014-1314-y] [Cited by in Crossref: 288] [Cited by in F6Publishing: 278] [Article Influence: 36.0] [Reference Citation Analysis]
438 Brenna S, Krisp C, Altmeppen HC, Magnus T, Puig B. Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective. Int J Mol Sci 2021;22:1365. [PMID: 33573018 DOI: 10.3390/ijms22031365] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
439 Ferrara D, Pasetto L, Bonetto V, Basso M. Role of Extracellular Vesicles in Amyotrophic Lateral Sclerosis. Front Neurosci 2018;12:574. [PMID: 30174585 DOI: 10.3389/fnins.2018.00574] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 5.3] [Reference Citation Analysis]
440 Bourdenx M, Bezard E, Dehay B. Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. Front Neuroanat 2014;8:83. [PMID: 25177278 DOI: 10.3389/fnana.2014.00083] [Cited by in Crossref: 53] [Cited by in F6Publishing: 52] [Article Influence: 6.6] [Reference Citation Analysis]
441 Sacino AN, Brooks MM, Chakrabarty P, Saha K, Khoshbouei H, Golde TE, Giasson BI. Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology. J Neurochem 2017;140:662-78. [PMID: 27424880 DOI: 10.1111/jnc.13743] [Cited by in Crossref: 38] [Cited by in F6Publishing: 36] [Article Influence: 6.3] [Reference Citation Analysis]
442 Kolonics F, Szeifert V, Timár CI, Ligeti E, Lőrincz ÁM. The Functional Heterogeneity of Neutrophil-Derived Extracellular Vesicles Reflects the Status of the Parent Cell. Cells 2020;9:E2718. [PMID: 33353087 DOI: 10.3390/cells9122718] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 3.5] [Reference Citation Analysis]
443 Katorcha E, Makarava N, Lee YJ, Lindberg I, Monteiro MJ, Kovacs GG, Baskakov IV. Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy. PLoS Pathog 2017;13:e1006563. [PMID: 28797122 DOI: 10.1371/journal.ppat.1006563] [Cited by in Crossref: 25] [Cited by in F6Publishing: 24] [Article Influence: 5.0] [Reference Citation Analysis]
444 Tan LY, Tang KH, Lim LYY, Ong JX, Park H, Jung S. α-Synuclein at the Presynaptic Axon Terminal as a Double-Edged Sword. Biomolecules 2022;12:507. [DOI: 10.3390/biom12040507] [Reference Citation Analysis]
445 Kalia LV, Kalia SK, McLean PJ, Lozano AM, Lang AE. α-Synuclein oligomers and clinical implications for Parkinson disease. Ann Neurol 2013;73:155-69. [PMID: 23225525 DOI: 10.1002/ana.23746] [Cited by in Crossref: 194] [Cited by in F6Publishing: 192] [Article Influence: 19.4] [Reference Citation Analysis]
446 Morrow KA, Ochoa CD, Balczon R, Zhou C, Cauthen L, Alexeyev M, Schmalzer KM, Frank DW, Stevens T. Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy. Am J Physiol Lung Cell Mol Physiol 2016;310:L337-53. [PMID: 26637633 DOI: 10.1152/ajplung.00103.2015] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 3.0] [Reference Citation Analysis]
447 Plotegher N, Gratton E, Bubacco L. Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells. Biochim Biophys Acta 2014;1840:2014-24. [PMID: 24561157 DOI: 10.1016/j.bbagen.2014.02.013] [Cited by in Crossref: 56] [Cited by in F6Publishing: 50] [Article Influence: 7.0] [Reference Citation Analysis]
448 Lim YJ, Lee SJ. Are exosomes the vehicle for protein aggregate propagation in neurodegenerative diseases? Acta Neuropathol Commun 2017;5:64. [PMID: 28851422 DOI: 10.1186/s40478-017-0467-z] [Cited by in Crossref: 29] [Cited by in F6Publishing: 28] [Article Influence: 5.8] [Reference Citation Analysis]
449 Anakor E, Le Gall L, Dumonceaux J, Duddy WJ, Duguez S. Exosomes in Ageing and Motor Neurone Disease: Biogenesis, Uptake Mechanisms, Modifications in Disease and Uses in the Development of Biomarkers and Therapeutics. Cells 2021;10:2930. [PMID: 34831153 DOI: 10.3390/cells10112930] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
450 Xing Y, Cheng Z, Wang R, Lv C, James TD, Yu F. Analysis of extracellular vesicles as emerging theranostic nanoplatforms. Coordination Chemistry Reviews 2020;424:213506. [DOI: 10.1016/j.ccr.2020.213506] [Cited by in Crossref: 9] [Cited by in F6Publishing: 3] [Article Influence: 4.5] [Reference Citation Analysis]
451 Levy E. Exosomes in the Diseased Brain: First Insights from In vivo Studies. Front Neurosci 2017;11:142. [PMID: 28386213 DOI: 10.3389/fnins.2017.00142] [Cited by in Crossref: 41] [Cited by in F6Publishing: 43] [Article Influence: 8.2] [Reference Citation Analysis]
452 Jo M, Lee S, Jeon YM, Kim S, Kwon Y, Kim HJ. The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies. Exp Mol Med 2020;52:1652-62. [PMID: 33051572 DOI: 10.1038/s12276-020-00513-7] [Cited by in Crossref: 18] [Cited by in F6Publishing: 12] [Article Influence: 9.0] [Reference Citation Analysis]
453 Lai CP, Breakefield XO. Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Front Physiol. 2012;3:228. [PMID: 22754538 DOI: 10.3389/fphys.2012.00228] [Cited by in Crossref: 154] [Cited by in F6Publishing: 178] [Article Influence: 15.4] [Reference Citation Analysis]
454 Wang B, Underwood R, Kamath A, Britain C, McFerrin MB, McLean PJ, Volpicelli-Daley LA, Whitaker RH, Placzek WJ, Becker K, Ma J, Yacoubian TA. 14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein. J Neurosci 2018;38:8211-32. [PMID: 30093536 DOI: 10.1523/JNEUROSCI.1134-18.2018] [Cited by in Crossref: 26] [Cited by in F6Publishing: 21] [Article Influence: 6.5] [Reference Citation Analysis]
455 Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T. LRRK2 secretion in exosomes is regulated by 14-3-3. Hum Mol Genet. 2013;22:4988-5000. [PMID: 23886663 DOI: 10.1093/hmg/ddt346] [Cited by in Crossref: 108] [Cited by in F6Publishing: 104] [Article Influence: 12.0] [Reference Citation Analysis]
456 Koh YH, Tan LY, Ng SY. Patient-Derived Induced Pluripotent Stem Cells and Organoids for Modeling Alpha Synuclein Propagation in Parkinson's Disease. Front Cell Neurosci 2018;12:413. [PMID: 30483063 DOI: 10.3389/fncel.2018.00413] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
457 Sampaio-Marques B, Ludovico P. Sirtuins and proteolytic systems: implications for pathogenesis of synucleinopathies. Biomolecules 2015;5:735-57. [PMID: 25946078 DOI: 10.3390/biom5020735] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
458 Chen HJ, Anagnostou G, Chai A, Withers J, Morris A, Adhikaree J, Pennetta G, de Belleroche JS. Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis. J Biol Chem 2010;285:40266-81. [PMID: 20940299 DOI: 10.1074/jbc.M110.161398] [Cited by in Crossref: 114] [Cited by in F6Publishing: 69] [Article Influence: 9.5] [Reference Citation Analysis]
459 Schapansky J, Khasnavis S, DeAndrade MP, Nardozzi JD, Falkson SR, Boyd JD, Sanderson JB, Bartels T, Melrose HL, LaVoie MJ. Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons. Neurobiol Dis 2018;111:26-35. [PMID: 29246723 DOI: 10.1016/j.nbd.2017.12.005] [Cited by in Crossref: 63] [Cited by in F6Publishing: 58] [Article Influence: 12.6] [Reference Citation Analysis]
460 Harischandra DS, Rokad D, Neal ML, Ghaisas S, Manne S, Sarkar S, Panicker N, Zenitsky G, Jin H, Lewis M, Huang X, Anantharam V, Kanthasamy A, Kanthasamy AG. Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein. Sci Signal 2019;12:eaau4543. [PMID: 30862700 DOI: 10.1126/scisignal.aau4543] [Cited by in Crossref: 59] [Cited by in F6Publishing: 55] [Article Influence: 19.7] [Reference Citation Analysis]
461 Bae EJ, Lee HJ, Rockenstein E, Ho DH, Park EB, Yang NY, Desplats P, Masliah E, Lee SJ. Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission. J Neurosci. 2012;32:13454-13469. [PMID: 23015436 DOI: 10.1523/jneurosci.1292-12.2012] [Cited by in Crossref: 212] [Cited by in F6Publishing: 143] [Article Influence: 21.2] [Reference Citation Analysis]
462 Bowers EC, Hassanin AAI, Ramos KS. In vitro models of exosome biology and toxicology: New frontiers in biomedical research. Toxicol In Vitro 2020;64:104462. [PMID: 31628015 DOI: 10.1016/j.tiv.2019.02.016] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.7] [Reference Citation Analysis]
463 Soria FN, Pampliega O, Bourdenx M, Meissner WG, Bezard E, Dehay B. Exosomes, an Unmasked Culprit in Neurodegenerative Diseases. Front Neurosci 2017;11:26. [PMID: 28197068 DOI: 10.3389/fnins.2017.00026] [Cited by in Crossref: 71] [Cited by in F6Publishing: 74] [Article Influence: 14.2] [Reference Citation Analysis]
464 Hernandez SM, Tikhonova EB, Karamyshev AL. Protein-Protein Interactions in Alpha-Synuclein Biogenesis: New Potential Targets in Parkinson's Disease. Front Aging Neurosci 2020;12:72. [PMID: 32256340 DOI: 10.3389/fnagi.2020.00072] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 2.5] [Reference Citation Analysis]
465 Vasili E, Dominguez-Meijide A, Outeiro TF. Spreading of α-Synuclein and Tau: A Systematic Comparison of the Mechanisms Involved. Front Mol Neurosci 2019;12:107. [PMID: 31105524 DOI: 10.3389/fnmol.2019.00107] [Cited by in Crossref: 38] [Cited by in F6Publishing: 35] [Article Influence: 12.7] [Reference Citation Analysis]
466 Gupta A, Pulliam L. Exosomes as mediators of neuroinflammation. J Neuroinflammation 2014;11:68. [PMID: 24694258 DOI: 10.1186/1742-2094-11-68] [Cited by in Crossref: 164] [Cited by in F6Publishing: 157] [Article Influence: 20.5] [Reference Citation Analysis]
467 Gonçalves SA, Macedo D, Raquel H, Simões PD, Giorgini F, Ramalho JS, Barral DC, Ferreira Moita L, Outeiro TF. shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity. PLoS Genet 2016;12:e1005995. [PMID: 27123591 DOI: 10.1371/journal.pgen.1005995] [Cited by in Crossref: 41] [Cited by in F6Publishing: 40] [Article Influence: 6.8] [Reference Citation Analysis]
468 Madsen DA, Schmidt SI, Blaabjerg M, Meyer M. Interaction between Parkin and α-Synuclein in PARK2-Mediated Parkinson's Disease. Cells 2021;10:283. [PMID: 33572534 DOI: 10.3390/cells10020283] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
469 Lee JY, Kim HS. Extracellular Vesicles in Neurodegenerative Diseases: A Double-Edged Sword. Tissue Eng Regen Med 2017;14:667-78. [PMID: 30603519 DOI: 10.1007/s13770-017-0090-x] [Cited by in Crossref: 15] [Cited by in F6Publishing: 17] [Article Influence: 3.0] [Reference Citation Analysis]
470 Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep 2013;14:389-94. [PMID: 23412472 DOI: 10.1038/embor.2013.15] [Cited by in Crossref: 334] [Cited by in F6Publishing: 324] [Article Influence: 37.1] [Reference Citation Analysis]
471 Ke T, Santamaria A, Rocha JBT, Tinkov AA, Lu R, Bowman AB, Aschner M. The Role of Human LRRK2 in Methylmercury-Induced Inhibition of Microvesicle Formation of Cephalic Neurons in Caenorhabditis elegans. Neurotox Res 2020;38:751-64. [PMID: 32725544 DOI: 10.1007/s12640-020-00262-5] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
472 Pampalakis G, Sykioti VS, Ximerakis M, Stefanakou-Kalakou I, Melki R, Vekrellis K, Sotiropoulou G. KLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species. Oncotarget 2017;8:14502-15. [PMID: 27845893 DOI: 10.18632/oncotarget.13264] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 4.2] [Reference Citation Analysis]
473 Lee HJ, Cho ED, Lee KW, Kim JH, Cho SG, Lee SJ. Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein. Exp Mol Med 2013;45:e22. [PMID: 23661100 DOI: 10.1038/emm.2013.45] [Cited by in Crossref: 123] [Cited by in F6Publishing: 124] [Article Influence: 13.7] [Reference Citation Analysis]
474 Beauchamp LC, Chan J, Hung LW, Padman BS, Vella LJ, Liu XM, Coleman B, Bush AI, Lazarou M, Hill AF, Jacobson L, Barnham KJ. Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease. Acta Neuropathol Commun 2018;6:57. [PMID: 29976255 DOI: 10.1186/s40478-018-0560-y] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.8] [Reference Citation Analysis]
475 Upadhya R, Shetty AK. Extracellular Vesicles for the Diagnosis and Treatment of Parkinson's Disease. Aging Dis 2021;12:1438-50. [PMID: 34527420 DOI: 10.14336/AD.2021.0516] [Reference Citation Analysis]
476 Lee JS, Lee SJ. Mechanism of Anti-α-Synuclein Immunotherapy. J Mov Disord 2016;9:14-9. [PMID: 26828212 DOI: 10.14802/jmd.15059] [Cited by in Crossref: 30] [Cited by in F6Publishing: 27] [Article Influence: 5.0] [Reference Citation Analysis]
477 Amro Z, Yool AJ, Collins-Praino LE. The potential role of glial cells in driving the prion-like transcellular propagation of tau in tauopathies. Brain Behav Immun Health 2021;14:100242. [PMID: 34589757 DOI: 10.1016/j.bbih.2021.100242] [Reference Citation Analysis]
478 Funk KE, Kuret J. Lysosomal fusion dysfunction as a unifying hypothesis for Alzheimer's disease pathology. Int J Alzheimers Dis 2012;2012:752894. [PMID: 22970406 DOI: 10.1155/2012/752894] [Cited by in Crossref: 12] [Cited by in F6Publishing: 28] [Article Influence: 1.2] [Reference Citation Analysis]
479 Wu X, Zheng T, Zhang B. Exosomes in Parkinson's Disease. Neurosci Bull 2017;33:331-8. [PMID: 28025780 DOI: 10.1007/s12264-016-0092-z] [Cited by in Crossref: 63] [Cited by in F6Publishing: 60] [Article Influence: 10.5] [Reference Citation Analysis]
480 Lööv C, Scherzer CR, Hyman BT, Breakefield XO, Ingelsson M. α-Synuclein in Extracellular Vesicles: Functional Implications and Diagnostic Opportunities. Cell Mol Neurobiol 2016;36:437-48. [PMID: 26993503 DOI: 10.1007/s10571-015-0317-0] [Cited by in Crossref: 38] [Cited by in F6Publishing: 35] [Article Influence: 6.3] [Reference Citation Analysis]
481 Jarvela TS, Lam HA, Helwig M, Lorenzen N, Otzen DE, McLean PJ, Maidment NT, Lindberg I. The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity. Proc Natl Acad Sci U S A 2016;113:E4708-15. [PMID: 27457957 DOI: 10.1073/pnas.1601091113] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 3.5] [Reference Citation Analysis]
482 Holmes BB, Diamond MI. Cellular mechanisms of protein aggregate propagation. Curr Opin Neurol 2012;25:721-6. [PMID: 23108252 DOI: 10.1097/WCO.0b013e32835a3ee0] [Cited by in Crossref: 53] [Cited by in F6Publishing: 28] [Article Influence: 5.9] [Reference Citation Analysis]
483 Frühbeis C, Fröhlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Möbius W, Goebbels S, Nave KA, Schneider A, Simons M, Klugmann M, Trotter J, Krämer-Albers EM. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol 2013;11:e1001604. [PMID: 23874151 DOI: 10.1371/journal.pbio.1001604] [Cited by in Crossref: 429] [Cited by in F6Publishing: 423] [Article Influence: 47.7] [Reference Citation Analysis]
484 Panicker N, Ge P, Dawson VL, Dawson TM. The cell biology of Parkinson's disease. J Cell Biol 2021;220:e202012095. [PMID: 33749710 DOI: 10.1083/jcb.202012095] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
485 Longhena F, Faustini G, Missale C, Pizzi M, Spano P, Bellucci A. The Contribution of α-Synuclein Spreading to Parkinson's Disease Synaptopathy. Neural Plast 2017;2017:5012129. [PMID: 28133550 DOI: 10.1155/2017/5012129] [Cited by in Crossref: 43] [Cited by in F6Publishing: 36] [Article Influence: 8.6] [Reference Citation Analysis]
486 Haque S, Sinha N, Ranjit S, Midde NM, Kashanchi F, Kumar S. Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication. Sci Rep 2017;7:16120. [PMID: 29170447 DOI: 10.1038/s41598-017-16301-9] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 4.4] [Reference Citation Analysis]
487 Yamada K, Iwatsubo T. Extracellular α-synuclein levels are regulated by neuronal activity. Mol Neurodegener 2018;13:9. [PMID: 29467003 DOI: 10.1186/s13024-018-0241-0] [Cited by in Crossref: 49] [Cited by in F6Publishing: 47] [Article Influence: 12.3] [Reference Citation Analysis]
488 Pinson MR, Chung DD, Adams AM, Scopice C, Payne EA, Sivakumar M, Miranda RC. Extracellular Vesicles in Premature Aging and Diseases in Adulthood Due to Developmental Exposures. Aging Dis 2021;12:1516-35. [PMID: 34527425 DOI: 10.14336/AD.2021.0322] [Reference Citation Analysis]
489 Mathews PM, Levy E. Exosome Production Is Key to Neuronal Endosomal Pathway Integrity in Neurodegenerative Diseases. Front Neurosci 2019;13:1347. [PMID: 31911768 DOI: 10.3389/fnins.2019.01347] [Cited by in Crossref: 22] [Cited by in F6Publishing: 20] [Article Influence: 7.3] [Reference Citation Analysis]
490 Bae EJ, Ho DH, Park E, Jung JW, Cho K, Hong JH, Lee HJ, Kim KP, Lee SJ. Lipid peroxidation product 4-hydroxy-2-nonenal promotes seeding-capable oligomer formation and cell-to-cell transfer of α-synuclein. Antioxid Redox Signal 2013;18:770-83. [PMID: 22867050 DOI: 10.1089/ars.2011.4429] [Cited by in Crossref: 65] [Cited by in F6Publishing: 57] [Article Influence: 6.5] [Reference Citation Analysis]
491 Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T. Microglia as modulators of exosomal alpha-synuclein transmission. Cell Death Dis 2019;10:174. [PMID: 30787269 DOI: 10.1038/s41419-019-1404-9] [Cited by in Crossref: 52] [Cited by in F6Publishing: 53] [Article Influence: 17.3] [Reference Citation Analysis]
492 Fellner L, Wenning GK, Stefanova N. Models of multiple system atrophy. Curr Top Behav Neurosci 2015;22:369-93. [PMID: 24338664 DOI: 10.1007/7854_2013_269] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 1.7] [Reference Citation Analysis]
493 Wang Q, Xue X, Huang Z, Wang Y. Microglia Share the Burden. Neurosci Bull 2022. [PMID: 35415798 DOI: 10.1007/s12264-022-00854-5] [Reference Citation Analysis]
494 Zoey FL, Palanivel M, Padmanabhan P, Gulyás B. Parkinson's Disease: A Nanotheranostic Approach Targeting Alpha-Synuclein Aggregation. Front Cell Dev Biol 2021;9:707441. [PMID: 34490255 DOI: 10.3389/fcell.2021.707441] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
495 Zhu H, Guariglia S, Yu RY, Li W, Brancho D, Peinado H, Lyden D, Salzer J, Bennett C, Chow CW. Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes. Mol Biol Cell 2013;24:1619-37, S1-3. [PMID: 23576546 DOI: 10.1091/mbc.E12-07-0544] [Cited by in Crossref: 53] [Cited by in F6Publishing: 48] [Article Influence: 5.9] [Reference Citation Analysis]
496 García-Yagüe ÁJ, Lastres-Becker I, Stefanis L, Vassilatis DK, Cuadrado A. α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks. Mol Neurobiol 2021;58:6697-711. [PMID: 34609698 DOI: 10.1007/s12035-021-02558-9] [Reference Citation Analysis]
497 El Turk F, De Genst E, Guilliams T, Fauvet B, Hejjaoui M, Di Trani J, Chiki A, Mittermaier A, Vendruscolo M, Lashuel HA, Dobson CM. Exploring the role of post-translational modifications in regulating α-synuclein interactions by studying the effects of phosphorylation on nanobody binding. Protein Sci 2018;27:1262-74. [PMID: 29603451 DOI: 10.1002/pro.3412] [Cited by in Crossref: 15] [Cited by in F6Publishing: 12] [Article Influence: 5.0] [Reference Citation Analysis]
498 Vella LJ, Hill AF, Cheng L. Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease. Int J Mol Sci 2016;17:173. [PMID: 26861304 DOI: 10.3390/ijms17020173] [Cited by in Crossref: 118] [Cited by in F6Publishing: 116] [Article Influence: 19.7] [Reference Citation Analysis]
499 Moons R, Konijnenberg A, Mensch C, Van Elzen R, Johannessen C, Maudsley S, Lambeir AM, Sobott F. Metal ions shape α-synuclein. Sci Rep 2020;10:16293. [PMID: 33004902 DOI: 10.1038/s41598-020-73207-9] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 4.0] [Reference Citation Analysis]
500 Yu Z, Shi M, Stewart T, Fernagut PO, Huang Y, Tian C, Dehay B, Atik A, Yang D, De Giorgi F, Ichas F, Canron MH, Ceravolo R, Frosini D, Kim HJ, Feng T, Meissner WG, Zhang J. Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction. Brain 2020;143:1780-97. [PMID: 32428221 DOI: 10.1093/brain/awaa110] [Cited by in Crossref: 9] [Cited by in F6Publishing: 12] [Article Influence: 9.0] [Reference Citation Analysis]
501 Natale G, Pompili E, Biagioni F, Paparelli S, Lenzi P, Fornai F. Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases. Eur J Histochem 2013;57:e5. [PMID: 23549464 DOI: 10.4081/ejh.2013.e5] [Cited by in Crossref: 9] [Cited by in F6Publishing: 13] [Article Influence: 1.0] [Reference Citation Analysis]