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For: Hartmann W, Digon-Söntgerath B, Koch A, Waha A, Endl E, Dani I, Denkhaus D, Goodyer CG, Sörensen N, Wiestler OD. Phosphatidylinositol 3’-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN. Clin Cancer Res. 2006;12:3019-3027. [PMID: 16707597 DOI: 10.1158/1078-0432.ccr-05-2187] [Cited by in Crossref: 100] [Cited by in F6Publishing: 56] [Article Influence: 6.3] [Reference Citation Analysis]
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10 Liu J, Zhang M, Kan Y, Wang W, Liu J, Gong J, Yang J. Nuclear Factor-κB Activating Protein Plays an Oncogenic Role in Neuroblastoma Tumorigenesis and Recurrence Through the Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway. Front Cell Dev Biol 2020;8:622793. [PMID: 33553160 DOI: 10.3389/fcell.2020.622793] [Reference Citation Analysis]
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12 Söderberg-Nauclér C, Johnsen JI. Cytomegalovirus in human brain tumors: Role in pathogenesis and potential treatment options. World J Exp Med 2015; 5(1): 1-10 [PMID: 25699229 DOI: 10.5493/wjem.v5.i1.1] [Cited by in CrossRef: 28] [Cited by in F6Publishing: 26] [Article Influence: 4.0] [Reference Citation Analysis]
13 Li X, Wu C, Chen N, Gu H, Yen A, Cao L, Wang E, Wang L. PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma. Oncotarget 2016;7:33440-50. [PMID: 26967052 DOI: 10.18632/oncotarget.7961] [Cited by in Crossref: 202] [Cited by in F6Publishing: 202] [Article Influence: 40.4] [Reference Citation Analysis]
14 Wang YB, Hu Y, Li Z, Wang P, Xue YX, Yao YL, Yu B, Liu YH. Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells. PLoS One 2013;8:e60834. [PMID: 23593320 DOI: 10.1371/journal.pone.0060834] [Cited by in Crossref: 18] [Cited by in F6Publishing: 19] [Article Influence: 2.0] [Reference Citation Analysis]
15 Thomaz A, Pinheiro KV, Souza BK, Gregianin L, Brunetto AL, Brunetto AT, de Farias CB, Jaeger MDC, Ramaswamy V, Nör C, Taylor MD, Roesler R. Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma. Front Pharmacol 2019;10:698. [PMID: 31297057 DOI: 10.3389/fphar.2019.00698] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
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17 Singh AR, Joshi S, Zulcic M, Alcaraz M, Garlich JR, Morales GA, Cho YJ, Bao L, Levy ML, Newbury R, Malicki D, Messer K, Crawford J, Durden DL. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma. PLoS One 2016;11:e0150836. [PMID: 26938241 DOI: 10.1371/journal.pone.0150836] [Cited by in Crossref: 20] [Cited by in F6Publishing: 16] [Article Influence: 3.3] [Reference Citation Analysis]
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19 Pei Y, Moore CE, Wang J, Tewari AK, Eroshkin A, Cho YJ, Witt H, Korshunov A, Read TA, Sun JL. An animal model of MYC-driven medulloblastoma. Cancer Cell. 2012;21:155-167. [PMID: 22340590 DOI: 10.1016/j.ccr.2011.12.021] [Cited by in Crossref: 201] [Cited by in F6Publishing: 182] [Article Influence: 20.1] [Reference Citation Analysis]
20 Ward SA, Rubin JB. Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain Tumorigenesis. Cancers (Basel) 2015;7:1484-98. [PMID: 26258793 DOI: 10.3390/cancers7030848] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.4] [Reference Citation Analysis]
21 Jiang T, Wu SH, He S, Wen FF, Gao XQ, Li YY. Clinical significance of expression of PI3Kp110α, PI3Kp110β, Bcl-2 and CyclinD1 in primary colorectal cancer and lymph node metastases. Shijie Huaren Xiaohua Zazhi 2015; 23(20): 3226-3234 [DOI: 10.11569/wcjd.v23.i20.3226] [Reference Citation Analysis]
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23 Wojtalla A, Salm F, Christiansen DG, Cremona T, Cwiek P, Shalaby T, Gross N, Grotzer MA, Arcaro A. Novel agents targeting the IGF-1R/PI3K pathway impair cell proliferation and survival in subsets of medulloblastoma and neuroblastoma. PLoS One 2012;7:e47109. [PMID: 23056595 DOI: 10.1371/journal.pone.0047109] [Cited by in Crossref: 13] [Cited by in F6Publishing: 17] [Article Influence: 1.3] [Reference Citation Analysis]
24 Gao Q, Ye F, Xia X, Xing H, Lu Y, Zhou J, Ma D. Correlation between PTEN expression and PI3K/Akt signal pathway in endometrial carcinoma. J Huazhong Univ Sci Technolog Med Sci 2009;29:59-63. [PMID: 19224164 DOI: 10.1007/s11596-009-0112-6] [Cited by in Crossref: 12] [Cited by in F6Publishing: 15] [Article Influence: 0.9] [Reference Citation Analysis]
25 Tsangaris GT, Papathanasiou C, Adamopoulos PG, Scorilas A, Vorgias CE, Prodromou N, Stathopoulou FT, Stravopodis DJ, Anagnostopoulos AK. Pediatric Ependymoma: A Proteomics Perspective. Cancer Genomics Proteomics 2017;14:127-36. [PMID: 28387652 DOI: 10.21873/cgp.20025] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
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27 Chen H, Wang X, Han J, Fan Z, Sadia S, Zhang R, Guo Y, Jiang Y, Wu Y. AKT and its related molecular feature in aged mice skin. PLoS One 2017;12:e0178969. [PMID: 28591208 DOI: 10.1371/journal.pone.0178969] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 1.6] [Reference Citation Analysis]
28 Holland H, Xu LX, Ahnert P, Kirsten H, Koschny R, Bauer M, Schober R, Meixensberger J, Krupp W. Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma. Pathol Res Pract 2013;209:541-7. [PMID: 23896263 DOI: 10.1016/j.prp.2013.06.001] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
29 Ceccarelli M, D'Andrea G, Micheli L, Gentile G, Cavallaro S, Merlino G, Papoff G, Tirone F. Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/-/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611. Front Oncol 2021;11:692053. [PMID: 34395258 DOI: 10.3389/fonc.2021.692053] [Reference Citation Analysis]
30 Yang F, Jove V, Xin H, Hedvat M, Van Meter TE, Yu H. Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways. Mol Cancer Res. 2010;8:35-45. [PMID: 20053726 DOI: 10.1158/1541-7786.mcr-09-0220] [Cited by in Crossref: 78] [Cited by in F6Publishing: 45] [Article Influence: 6.5] [Reference Citation Analysis]
31 Eckerdt F, Clymer J, Bell JB, Beauchamp EM, Blyth GT, Goldman S, Platanias LC. Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma. Sci Rep 2019;9:12822. [PMID: 31492956 DOI: 10.1038/s41598-019-49299-3] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
32 Eckerdt F, Bell JB, Beauchamp EM, Clymer J, Blyth GT, Kosciuczuk EM, Ma Q, Chen DZ, Horbinski C, Goldman S, Munshi HG, Hashizume R, Platanias LC. Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma. Mol Cancer Res 2019;17:1305-15. [PMID: 30842251 DOI: 10.1158/1541-7786.MCR-18-1193] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
33 Baocheng W, Zhao Y, Meng W, Han Y, Wang J, Liu F, Qin S, Ma J. Polymorphisms of insulin receptor substrate 2 are putative biomarkers for pediatric medulloblastoma: considering the genetic susceptibility and pathological diagnoses. Nagoya J Med Sci 2017;79:47-54. [PMID: 28303061 DOI: 10.18999/nagjms.79.1.47] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
34 Huang WS, Wang TB, He Y, Chen YJ, Zhong SL, Tan M. Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon cancer cell SW948. World J Gastroenterol 2012; 18(26): 3458-3464 [PMID: 22807617 DOI: 10.3748/wjg.v18.i26.3458] [Cited by in CrossRef: 2] [Cited by in F6Publishing: 3] [Article Influence: 0.2] [Reference Citation Analysis]
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