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For: Zhang J, Zhou F, Wu X, Zhang X, Chen Y, Zha BS, Niu F, Lu M, Hao G, Sun Y, Sun J, Peng Y, Wang G. Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation by 20(S)-ginsenoside Rh2 in MCF-7/Adr cells. Br J Pharmacol 2012;165:120-34. [PMID: 21615726 DOI: 10.1111/j.1476-5381.2011.01505.x] [Cited by in Crossref: 55] [Cited by in F6Publishing: 52] [Article Influence: 5.5] [Reference Citation Analysis]
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10 Chen XY, Qian F, Wang YY, Liu Y, Sun Y, Zha WB, Hao K, Zhou F, Wang GJ, Zhang JW. Ginsenoside 20(S)-Rh2 promotes cellular pharmacokinetics and intracellular antibacterial activity of levofloxacin against Staphylococcus aureus through drug efflux inhibition and subcellular stabilization. Acta Pharmacol Sin 2021;42:1930-41. [PMID: 34462563 DOI: 10.1038/s41401-021-00751-z] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
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12 Kang Y, Cao P, Liu X, Jin Y, Yang X, Zhang Z. Determination of the effect of berberine on epirubicin concentration in MCF-7 cells by LC-MS/MS: the mechanism of synergism explained by intracellular pharmacokinetics. Journal of Pharmaceutical and Biomedical Analysis 2022. [DOI: 10.1016/j.jpba.2022.114692] [Reference Citation Analysis]
13 Zhang J, Sun Y, Wang Y, Lu M, He J, Liu J, Chen Q, Zhang X, Zhou F, Wang G, Sun X. Non-antibiotic agent ginsenoside 20(S)-Rh2 enhanced the antibacterial effects of ciprofloxacin in vitro and in vivo as a potential NorA inhibitor. Eur J Pharmacol 2014;740:277-84. [PMID: 25054686 DOI: 10.1016/j.ejphar.2014.07.020] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 3.3] [Reference Citation Analysis]
14 Zang X, Wang G, Cai Q, Zheng X, Zhang J, Chen Q, Wu B, Zhu X, Hao H, Zhou F. A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport. Drug Metab Dispos 2018;46:542-51. [DOI: 10.1124/dmd.117.079442] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 2.3] [Reference Citation Analysis]
15 Feng SL, Luo HB, Cai L, Zhang J, Wang D, Chen YJ, Zhan HX, Jiang ZH, Xie Y. Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: in vitro and in vivo study. J Ginseng Res 2020;44:247-57. [PMID: 32148406 DOI: 10.1016/j.jgr.2018.10.007] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.5] [Reference Citation Analysis]
16 Yao L, Zhang JW, Chen B, Cai MM, Feng D, Wang QZ, Wang XY, Sun JG, Zheng YW, Wang GJ, Zhou F. Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin. Acta Pharmacol Sin 2020;41:866-78. [PMID: 31937930 DOI: 10.1038/s41401-019-0342-5] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
17 Shi J, Cao B, Zha WB, Wu XL, Liu LS, Xiao WJ, Gu RR, Sun RB, Yu XY, Zheng T, Li MJ, Wang XW, Zhou J, Mao Y, Ge C, Ma T, Xia WJ, Aa JY, Wang GJ, Liu CX. Pharmacokinetic interactions between 20(S)-ginsenoside Rh2 and the HIV protease inhibitor ritonavir in vitro and in vivo. Acta Pharmacol Sin 2013;34:1349-58. [PMID: 23892274 DOI: 10.1038/aps.2013.69] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 1.6] [Reference Citation Analysis]
18 Cao B, Li M, Zha W, Zhao Q, Gu R, Liu L, Shi J, Zhou J, Zhou F, Wu X, Wu Z, Wang G, Aa J. Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells. Metabolomics 2013;9:960-73. [PMID: 24039617 DOI: 10.1007/s11306-013-0517-x] [Cited by in Crossref: 46] [Cited by in F6Publishing: 46] [Article Influence: 5.1] [Reference Citation Analysis]
19 Liu D, Li Y, Yao N, Xu J, Chen Z, Yiu A, Zhang C, Ye W, Zhang D. Acerinol, a cyclolanstane triterpenoid from Cimicifuga acerina, reverses ABCB1-mediated multidrug resistance in HepG2/ADM and MCF-7/ADR cells. European Journal of Pharmacology 2014;733:34-44. [DOI: 10.1016/j.ejphar.2014.03.043] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 1.8] [Reference Citation Analysis]
20 Kullenberg F, Degerstedt O, Calitz C, Pavlović N, Balgoma D, Gråsjö J, Sjögren E, Hedeland M, Heindryckx F, Lennernäs H. In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma. Cells 2021;10:1717. [PMID: 34359887 DOI: 10.3390/cells10071717] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
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22 Oh S, Han H, Kang K, Lee Y, Lee M. Menadione serves as a substrate for P-glycoprotein: implication in chemosensitizing activity. Arch Pharm Res 2013;36:509-16. [DOI: 10.1007/s12272-013-0052-3] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 1.2] [Reference Citation Analysis]
23 Zhang J, Lu M, Zhou F, Sun H, Hao G, Wu X, Wang G. Key role of nuclear factor-κB in the cellular pharmacokinetics of adriamycin in MCF-7/Adr cells: the potential mechanism for synergy with 20(S)-ginsenoside Rh2. Drug Metab Dispos 2012;40:1900-8. [PMID: 22745335 DOI: 10.1124/dmd.112.045187] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 2.4] [Reference Citation Analysis]
24 Yun UJ, Lee JH, Koo KH, Ye SK, Kim SY, Lee CH, Kim YN. Lipid raft modulation by Rp1 reverses multidrug resistance via inactivating MDR-1 and Src inhibition. Biochem Pharmacol 2013;85:1441-53. [PMID: 23473805 DOI: 10.1016/j.bcp.2013.02.025] [Cited by in Crossref: 24] [Cited by in F6Publishing: 25] [Article Influence: 2.7] [Reference Citation Analysis]
25 An T, Zhang C, Han X, Wan G, Wang D, Yang Z, Wang Y, Zhang L, Wang Y. Hyaluronic acid-coated poly(β-amino) ester nanoparticles as carrier of doxorubicin for overcoming drug resistance in breast cancer cells. RSC Adv 2016;6:38624-36. [DOI: 10.1039/c6ra03997a] [Cited by in Crossref: 19] [Article Influence: 3.2] [Reference Citation Analysis]
26 Bao K. An elementary mathematical modeling of drug resistance in cancer. Math Biosci Eng 2020;18:339-53. [PMID: 33525095 DOI: 10.3934/mbe.2021018] [Reference Citation Analysis]
27 Lan XY, Chung TT, Huang CL, Lee YJ, Li WC. Traditional Herbal Medicine Mediated Regulations during Head and Neck Carcinogenesis. Biomolecules 2020;10:E1321. [PMID: 32942674 DOI: 10.3390/biom10091321] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
28 Xu XH, Li T, Fong CM, Chen X, Chen XJ, Wang YT, Huang MQ, Lu JJ. Saponins from Chinese Medicines as Anticancer Agents. Molecules 2016;21:E1326. [PMID: 27782048 DOI: 10.3390/molecules21101326] [Cited by in Crossref: 59] [Cited by in F6Publishing: 51] [Article Influence: 9.8] [Reference Citation Analysis]
29 Xu JF, Wan Y, Tang F, Chen L, Yang Y, Xia J, Wu JJ, Ao H, Peng C. Emerging Significance of Ginsenosides as Potentially Reversal Agents of Chemoresistance in Cancer Therapy. Front Pharmacol 2021;12:720474. [PMID: 34975466 DOI: 10.3389/fphar.2021.720474] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
30 Xiang L, Hu YF, Wu JS, Wang L, Huang WG, Xu CS, Meng XL, Wang P. Semi-Mechanism-Based Pharmacodynamic Model for the Anti-Inflammatory Effect of Baicalein in LPS-Stimulated RAW264.7 Macrophages. Front Pharmacol 2018;9:793. [PMID: 30072902 DOI: 10.3389/fphar.2018.00793] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 1.8] [Reference Citation Analysis]
31 Chen Q, Chen H, Wang W, Liu J, Liu W, Ni P, Sang G, Wang G, Zhou F, Zhang J. Glycyrrhetic acid, but not glycyrrhizic acid, strengthened entecavir activity by promoting its subcellular distribution in the liver via efflux inhibition. Eur J Pharm Sci 2017;106:313-27. [PMID: 28627473 DOI: 10.1016/j.ejps.2017.06.015] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 4.2] [Reference Citation Analysis]
32 Li Y, Lu L, Wang L, Qu W, Liu W, Xie Y, Zheng H, Wang Y, Qi X, Hu M, Zhu L, Liu Z. Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol. Mol Pharm 2018;15:5602-14. [PMID: 30376625 DOI: 10.1021/acs.molpharmaceut.8b00782] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
33 Liu WY, Zhang JW, Yao XQ, Jiang C, He JC, Ni P, Liu JL, Chen QY, Li QR, Zang XJ, Yao L, Liu YZ, Wang ML, Shen PQ, Wang GJ, Zhou F. Shenmai injection enhances the cytotoxicity of chemotherapeutic drugs against colorectal cancers via improving their subcellular distribution. Acta Pharmacol Sin 2017;38:264-76. [PMID: 27867186 DOI: 10.1038/aps.2016.99] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 4.6] [Reference Citation Analysis]
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36 Liu J, Yan F, Chen H, Wang W, Liu W, Hao K, Wang G, Zhou F, Zhang J. A novel individual-cell-based mathematical model based on multicellular tumour spheroids for evaluating doxorubicin-related delivery in avascular regions. Br J Pharmacol 2017;174:2862-79. [PMID: 28608595 DOI: 10.1111/bph.13909] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
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40 Liu J, Geng T, Duan K, Gao X, Huang C, Wang J, Huang W, Huang L, Wang Z, Xiao W. Cellular pharmacokinetics and pharmacodynamics mechanisms of ginkgo diterpene lactone and its modulation of P‐glycoprotein expression in human SH‐SY5Y cells. Biomedical Chromatography 2019;33. [DOI: 10.1002/bmc.4692] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
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44 Zhang J, Li W, Yuan Q, Zhou J, Zhang J, Cao Y, Fu G, Hu W. Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells. Front Pharmacol 2019;10:1331. [PMID: 31780945 DOI: 10.3389/fphar.2019.01331] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
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47 Yun UJ, Lee IH, Lee JS, Shim J, Kim YN. Ginsenoside Rp1, A Ginsenoside Derivative, Augments Anti-Cancer Effects of Actinomycin D via Downregulation of an AKT-SIRT1 Pathway. Cancers (Basel) 2020;12:E605. [PMID: 32151067 DOI: 10.3390/cancers12030605] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
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49 Liu J, Zhou F, Chen Q, Kang A, Lu M, Liu W, Zang X, Wang G, Zhang J. Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice. Sci Rep 2015;5:13558. [PMID: 26324318 DOI: 10.1038/srep13558] [Cited by in Crossref: 24] [Cited by in F6Publishing: 17] [Article Influence: 3.4] [Reference Citation Analysis]
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51 Jiang S, Luo Y, Zhan Z, Tang Z, Zou J, Ying Y, Lin H, Huang D, Luo L. AMP-activated protein kinase re-sensitizes A549 to paclitaxel via up-regulating solute carrier organic anion transporter family member 1B3 expression. Cellular Signalling 2022;91:110215. [DOI: 10.1016/j.cellsig.2021.110215] [Reference Citation Analysis]
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