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For: Nakashima S, Hiraku Y, Tada-Oikawa S, Hishita T, Gabazza EC, Tamaki S, Imoto I, Adachi Y, Kawanishi S. Vacuolar H+-ATPase inhibitor induces apoptosis via lysosomal dysfunction in the human gastric cancer cell line MKN-1. J Biochem. 2003;134:359-364. [PMID: 14561721 DOI: 10.1093/jb/mvg153] [Cited by in Crossref: 71] [Cited by in F6Publishing: 73] [Article Influence: 3.7] [Reference Citation Analysis]
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1 Haugen ØP, Khuu C, Weidemann HM, Utheim TP, Bergersen LH. Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells. Gene 2022;822:146346. [PMID: 35182679 DOI: 10.1016/j.gene.2022.146346] [Reference Citation Analysis]
2 Abulikemu A, Zhao X, Qi Y, Liu Y, Wang J, Zhou W, Duan H, Li Y, Sun Z, Guo C. Lysosomal impairment-mediated autophagy dysfunction responsible for the vascular endothelial apoptosis caused by silica nanoparticle via ROS/PARP1/AIF signaling pathway. Environ Pollut 2022;:119202. [PMID: 35358632 DOI: 10.1016/j.envpol.2022.119202] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
3 Iessi E, Vona R, Cittadini C, Matarrese P. Targeting the Interplay between Cancer Metabolic Reprogramming and Cell Death Pathways as a Viable Therapeutic Path. Biomedicines 2021;9:1942. [PMID: 34944758 DOI: 10.3390/biomedicines9121942] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
4 Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y. Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1. Food Chem Toxicol 2021;157:112540. [PMID: 34500008 DOI: 10.1016/j.fct.2021.112540] [Cited by in Crossref: 2] [Article Influence: 1.0] [Reference Citation Analysis]
5 Machado ER, Annunziata I, van de Vlekkert D, Grosveld GC, d'Azzo A. Lysosomes and Cancer Progression: A Malignant Liaison. Front Cell Dev Biol 2021;9:642494. [PMID: 33718382 DOI: 10.3389/fcell.2021.642494] [Cited by in Crossref: 7] [Cited by in F6Publishing: 9] [Article Influence: 3.5] [Reference Citation Analysis]
6 Hu M, Carraway KL 3rd. Repurposing Cationic Amphiphilic Drugs and Derivatives to Engage Lysosomal Cell Death in Cancer Treatment. Front Oncol 2020;10:605361. [PMID: 33425762 DOI: 10.3389/fonc.2020.605361] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
7 Chen R, Jäättelä M, Liu B. Lysosome as a Central Hub for Rewiring PH Homeostasis in Tumors. Cancers (Basel) 2020;12:E2437. [PMID: 32867178 DOI: 10.3390/cancers12092437] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 5.0] [Reference Citation Analysis]
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10 Shaikh S, Nandy SK, Cantí C, Lavandero S. Bafilomycin-A1 and ML9 Exert Different Lysosomal Actions to Induce Cell Death. Curr Mol Pharmacol 2019;12:261-71. [PMID: 30854984 DOI: 10.2174/1874467212666190308131250] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
11 Ward C, Meehan J, Gray ME, Murray AF, Argyle DJ, Kunkler IH, Langdon SP. The impact of tumour pH on cancer progression: strategies for clinical intervention. Exploration of Targeted Anti-tumor Therapy 2020;1:71-100. [DOI: 10.37349/etat.2020.00005] [Cited by in Crossref: 30] [Cited by in F6Publishing: 30] [Article Influence: 10.0] [Reference Citation Analysis]
12 Zhang C, Feng X, He L, Zhang Y, Shao L. The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells. J Nanobiotechnology 2020;18:52. [PMID: 32188458 DOI: 10.1186/s12951-020-00605-6] [Cited by in Crossref: 16] [Cited by in F6Publishing: 17] [Article Influence: 5.3] [Reference Citation Analysis]
13 Xue YW, Hayata A, Itoh H, Inoue M. Biological Effects of a Simplified Synthetic Analogue of Ion-Channel-Forming Polytheonamide B on Plasma Membrane and Lysosomes. Chemistry 2019;25:15198-204. [PMID: 31549755 DOI: 10.1002/chem.201903974] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
14 Patil R, Powrozek O, Kumar B, Seibel W, Beaman K, Waris G, Sharma-walia N, Patil S. Bisbenzimidazoles: Anticancer Vacuolar (H+)-ATPase Inhibitors. Chemistry and Applications of Benzimidazole and its Derivatives 2019. [DOI: 10.5772/intechopen.85231] [Reference Citation Analysis]
15 Stamenkovic M, Janjetovic K, Paunovic V, Ciric D, Kravic-stevovic T, Trajkovic V. Comparative analysis of cell death mechanisms induced by lysosomal autophagy inhibitors. European Journal of Pharmacology 2019;859:172540. [DOI: 10.1016/j.ejphar.2019.172540] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 3.3] [Reference Citation Analysis]
16 Tan XY, Wang X, Liu QS, Xie XQ, Li Y, Li BQ, Li ZQ, Xia QY, Zhao P. Inhibition of silkworm vacuolar-type ATPase activity by its inhibitor Bafilomycin A1 induces caspase-dependent apoptosis in an embryonic cell line of silkworm. Arch Insect Biochem Physiol 2018;99:e21507. [PMID: 30246413 DOI: 10.1002/arch.21507] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
17 Martins BX, Arruda RF, Costa GA, Jerdy H, de Souza SB, Santos JM, de Freitas WR, Kanashiro MM, de Carvalho ECQ, Sant'Anna NF, Antunes F, Martinez-Zaguilan R, Souad S, Okorokova-Façanha AL, Façanha AR. Myrtenal-induced V-ATPase inhibition - A toxicity mechanism behind tumor cell death and suppressed migration and invasion in melanoma. Biochim Biophys Acta Gen Subj 2019;1863:1-12. [PMID: 30279148 DOI: 10.1016/j.bbagen.2018.09.006] [Cited by in Crossref: 20] [Cited by in F6Publishing: 20] [Article Influence: 4.0] [Reference Citation Analysis]
18 Hayata A, Itoh H, Inoue M. Solid-Phase Total Synthesis and Dual Mechanism of Action of the Channel-Forming 48-mer Peptide Polytheonamide B. J Am Chem Soc 2018;140:10602-11. [PMID: 30040396 DOI: 10.1021/jacs.8b06755] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 3.0] [Reference Citation Analysis]
19 Domagala A, Fidyt K, Bobrowicz M, Stachura J, Szczygiel K, Firczuk M. Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy. Int J Mol Sci 2018;19:E2256. [PMID: 30071644 DOI: 10.3390/ijms19082256] [Cited by in Crossref: 41] [Cited by in F6Publishing: 44] [Article Influence: 8.2] [Reference Citation Analysis]
20 Lei Y, Wang C, Jiang Q, Sun X, Du Y, Zhu Y, Lu Y. Calpain activation and disturbance of autophagy are induced in cortical neurons in vitro by exposure to HA/β-Ga2O3:Cr3+ nanoparticles. PeerJ 2018;6:e4365. [PMID: 29441243 DOI: 10.7717/peerj.4365] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
21 Iessi E, Logozzi M, Mizzoni D, Di Raimo R, Supuran CT, Fais S. Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy. Metabolites 2017;8:E2. [PMID: 29295495 DOI: 10.3390/metabo8010002] [Cited by in Crossref: 35] [Cited by in F6Publishing: 42] [Article Influence: 5.8] [Reference Citation Analysis]
22 Licon-Munoz Y, Michel V, Fordyce CA, Parra KJ. F-actin reorganization by V-ATPase inhibition in prostate cancer. Biol Open 2017;6:1734-44. [PMID: 29038303 DOI: 10.1242/bio.028837] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 2.3] [Reference Citation Analysis]
23 Wiedmer T, Blank A, Pantasis S, Normand L, Bill R, Krebs P, Tschan MP, Marinoni I, Perren A. Autophagy Inhibition Improves Sunitinib Efficacy in Pancreatic Neuroendocrine Tumors via a Lysosome-dependent Mechanism. Mol Cancer Ther 2017;16:2502-15. [PMID: 28729403 DOI: 10.1158/1535-7163.MCT-17-0136] [Cited by in Crossref: 41] [Cited by in F6Publishing: 44] [Article Influence: 6.8] [Reference Citation Analysis]
24 Miyayama T, Fujiki K, Matsuoka M. Silver nanoparticles induce lysosomal-autophagic defects and decreased expression of transcription factor EB in A549 human lung adenocarcinoma cells. Toxicol In Vitro 2018;46:148-54. [PMID: 28987793 DOI: 10.1016/j.tiv.2017.10.009] [Cited by in Crossref: 22] [Cited by in F6Publishing: 24] [Article Influence: 3.7] [Reference Citation Analysis]
25 Lu ZN, Tian B, Guo XL. Repositioning of proton pump inhibitors in cancer therapy. Cancer Chemother Pharmacol 2017;80:925-37. [PMID: 28861639 DOI: 10.1007/s00280-017-3426-2] [Cited by in Crossref: 37] [Cited by in F6Publishing: 43] [Article Influence: 6.2] [Reference Citation Analysis]
26 Eyraud V, Balmand S, Karaki L, Rahioui I, Sivignon C, Delmas AF, Royer C, Rahbé Y, Da Silva P, Gressent F. The interaction of the bioinsecticide PA1b (Pea Albumin 1 subunit b) with the insect V-ATPase triggers apoptosis. Sci Rep 2017;7:4902. [PMID: 28687751 DOI: 10.1038/s41598-017-05315-y] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
27 Asgharzadeh MR, Barar J, Pourseif MM, Eskandani M, Jafari Niya M, Mashayekhi MR, Omidi Y. Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapy. Bioimpacts 2017;7:115-33. [PMID: 28752076 DOI: 10.15171/bi.2017.15] [Cited by in Crossref: 70] [Cited by in F6Publishing: 73] [Article Influence: 11.7] [Reference Citation Analysis]
28 Wang P, Wang L, Sha J, Lou G, Lu N, Hang B, Mao JH, Zou X. Expression and Transcriptional Regulation of Human ATP6V1A Gene in Gastric Cancers. Sci Rep 2017;7:3015. [PMID: 28592880 DOI: 10.1038/s41598-017-03021-3] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
29 Kitazawa S, Nishizawa S, Nakagawa H, Funata M, Nishimura K, Soga T, Hara T. Cancer with low cathepsin D levels is susceptible to vacuolar (H+ )-ATPase inhibition. Cancer Sci 2017;108:1185-93. [PMID: 28317223 DOI: 10.1111/cas.13240] [Cited by in Crossref: 12] [Cited by in F6Publishing: 14] [Article Influence: 2.0] [Reference Citation Analysis]
30 Yan Y, Jiang K, Liu P, Zhang X, Dong X, Gao J, Liu Q, Barr MP, Zhang Q, Hou X, Meng S, Gong P. Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways. Sci Rep 2016;6:37052. [PMID: 27845389 DOI: 10.1038/srep37052] [Cited by in Crossref: 54] [Cited by in F6Publishing: 59] [Article Influence: 7.7] [Reference Citation Analysis]
31 Jäättelä M, Kallunki T. Lysosome and Cancer. Lysosomes: Biology, Diseases, and Therapeutics 2016. [DOI: 10.1002/9781118978320.ch10] [Reference Citation Analysis]
32 Mao B, Tsai J, Chen C, Yan S, Wang Y. Mechanisms of silver nanoparticle-induced toxicity and important role of autophagy. Nanotoxicology 2016;10:1021-40. [DOI: 10.1080/17435390.2016.1189614] [Cited by in Crossref: 151] [Cited by in F6Publishing: 144] [Article Influence: 21.6] [Reference Citation Analysis]
33 Schneider LS, Ulrich M, Lehr T, Menche D, Müller R, von Schwarzenberg K. MDM2 antagonist nutlin-3a sensitizes tumors to V-ATPase inhibition. Mol Oncol 2016;10:1054-62. [PMID: 27157929 DOI: 10.1016/j.molonc.2016.04.005] [Cited by in Crossref: 12] [Cited by in F6Publishing: 16] [Article Influence: 1.7] [Reference Citation Analysis]
34 Miyayama T, Matsuoka M. Involvement of lysosomal dysfunction in silver nanoparticle-induced cellular damage in A549 human lung alveolar epithelial cells. J Occup Med Toxicol 2016;11:1. [PMID: 26759602 DOI: 10.1186/s12995-016-0090-0] [Cited by in Crossref: 29] [Cited by in F6Publishing: 36] [Article Influence: 4.1] [Reference Citation Analysis]
35 Gölz JP, Bockelmann S, Mayer K, Steinhoff H, Wieczorek H, Huss M, Klare JP, Menche D. EPR Studies of V-ATPase with Spin-Labeled Inhibitors DCC and Archazolid: Interaction Dynamics with Proton Translocating Subunit c. ChemMedChem 2016;11:420-8. [DOI: 10.1002/cmdc.201500500] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 1.5] [Reference Citation Analysis]
36 Fuchs R, Stracke A, Ebner N, Zeller CW, Raninger AM, Schittmayer M, Kueznik T, Absenger-Novak M, Birner-Gruenberger R. The cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P. Toxicology 2015;338:17-29. [PMID: 26449523 DOI: 10.1016/j.tox.2015.09.008] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
37 Lu X, Chen L, Chen Y, Shao Q, Qin W. Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expression. Exp Ther Med 2015;10:1829-34. [PMID: 26640557 DOI: 10.3892/etm.2015.2758] [Cited by in Crossref: 20] [Cited by in F6Publishing: 23] [Article Influence: 2.5] [Reference Citation Analysis]
38 Walsh M, Fais S, Spugnini EP, Harguindey S, Abu Izneid T, Scacco L, Williams P, Allegrucci C, Rauch C, Omran Z. Proton pump inhibitors for the treatment of cancer in companion animals. J Exp Clin Cancer Res 2015;34:93. [PMID: 26337905 DOI: 10.1186/s13046-015-0204-z] [Cited by in Crossref: 27] [Cited by in F6Publishing: 28] [Article Influence: 3.4] [Reference Citation Analysis]
39 Kao M, Rao YK, Hsieh Y, Weng S, Lu T, Tzeng DT, Liu J, Lin C, Lai C, Tzeng Y. A cyclohexadepsipeptide from entomogenous fungi Metarhizium anisopliae inhibits the Helicobacter pylori induced pathogenesis through attenuation of vacuolating cytotoxin-A activity. Process Biochemistry 2015;50:134-9. [DOI: 10.1016/j.procbio.2014.10.017] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
40 Yuan N, Song L, Zhang S, Lin W, Cao Y, Xu F, Fang Y, Wang Z, Zhang H, Li X. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica. 2015;100:345-356. [PMID: 25512644 DOI: 10.3324/haematol.2014.113324] [Cited by in Crossref: 97] [Cited by in F6Publishing: 105] [Article Influence: 10.8] [Reference Citation Analysis]
41 Cerella C, Teiten M, Radogna F, Dicato M, Diederich M. From nature to bedside: Pro-survival and cell death mechanisms as therapeutic targets in cancer treatment. Biotechnology Advances 2014;32:1111-22. [DOI: 10.1016/j.biotechadv.2014.03.006] [Cited by in Crossref: 48] [Cited by in F6Publishing: 53] [Article Influence: 5.3] [Reference Citation Analysis]
42 Kobia F, Duchi S, Deflorian G, Vaccari T. Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling. Mol Oncol 2014;8:207-20. [PMID: 24309677 DOI: 10.1016/j.molonc.2013.11.002] [Cited by in Crossref: 46] [Cited by in F6Publishing: 47] [Article Influence: 4.6] [Reference Citation Analysis]
43 Müller C, Maeso I, Wittbrodt J, Martínez-Morales JR. The medaka mutation tintachina sheds light on the evolution of V-ATPase B subunits in vertebrates. Sci Rep 2013;3:3217. [PMID: 24225653 DOI: 10.1038/srep03217] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
44 Kallifatidis G, Hoepfner D, Jaeg T, Guzmán EA, Wright AE. The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Mar Drugs 2013;11:3500-16. [PMID: 24048269 DOI: 10.3390/md11093500] [Cited by in Crossref: 41] [Cited by in F6Publishing: 43] [Article Influence: 4.1] [Reference Citation Analysis]
45 Yoshimine S, Kikuchi E, Kosaka T, Mikami S, Miyajima A, Okada Y, Oya M. Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma. Br J Cancer 2013;108:2312-20. [PMID: 23674090 DOI: 10.1038/bjc.2013.216] [Cited by in Crossref: 19] [Cited by in F6Publishing: 22] [Article Influence: 1.9] [Reference Citation Analysis]
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47 Zhang Y, Yang ND, Zhou F, Shen T, Duan T, Zhou J, Shi Y, Zhu XQ, Shen HM. (-)-Epigallocatechin-3-gallate induces non-apoptotic cell death in human cancer cells via ROS-mediated lysosomal membrane permeabilization. PLoS One. 2012;7:e46749. [PMID: 23056433 DOI: 10.1371/journal.pone.0046749] [Cited by in Crossref: 63] [Cited by in F6Publishing: 68] [Article Influence: 5.7] [Reference Citation Analysis]
48 Koshkaryev A, Piroyan A, Torchilin VP. Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes. Cancer Biol Ther 2012;13:50-60. [PMID: 22336588 DOI: 10.4161/cbt.13.1.18871] [Cited by in Crossref: 71] [Cited by in F6Publishing: 74] [Article Influence: 6.5] [Reference Citation Analysis]
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50 Arnandis T, Ferrer-Vicens I, García-Trevijano ER, Miralles VJ, García C, Torres L, Viña JR, Zaragozá R. Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization. Cell Death Differ 2012;19:1536-48. [PMID: 22555453 DOI: 10.1038/cdd.2012.46] [Cited by in Crossref: 43] [Cited by in F6Publishing: 45] [Article Influence: 3.9] [Reference Citation Analysis]
51 Li D, Hérault K, Isacoff EY, Oheim M, Ropert N. Optogenetic activation of LiGluR-expressing astrocytes evokes anion channel-mediated glutamate release. J Physiol 2012;590:855-73. [PMID: 22219341 DOI: 10.1113/jphysiol.2011.219345] [Cited by in Crossref: 56] [Cited by in F6Publishing: 64] [Article Influence: 5.1] [Reference Citation Analysis]
52 Ma X, Wu Y, Jin S, Tian Y, Zhang X, Zhao Y, Yu L, Liang XJ. Gold nanoparticles induce autophagosome accumulation through size-dependent nanoparticle uptake and lysosome impairment. ACS Nano 2011;5:8629-39. [PMID: 21974862 DOI: 10.1021/nn202155y] [Cited by in Crossref: 434] [Cited by in F6Publishing: 464] [Article Influence: 36.2] [Reference Citation Analysis]
53 Chuang HC, Huang CC, Chien CY, Chuang JH. Toll-like receptor 3-mediated tumor invasion in head and neck cancer. Oral Oncol 2012;48:226-32. [PMID: 22070917 DOI: 10.1016/j.oraloncology.2011.10.008] [Cited by in Crossref: 32] [Cited by in F6Publishing: 33] [Article Influence: 2.7] [Reference Citation Analysis]
54 Rommelaere G, Michel S, Malaisse J, Charlier S, Arnould T, Renard P. Hypersensitivity of A8344G MERRF mutated cybrid cells to staurosporine-induced cell death is mediated by calcium-dependent activation of calpains. Int J Biochem Cell Biol 2012;44:139-49. [PMID: 22037425 DOI: 10.1016/j.biocel.2011.10.009] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 0.8] [Reference Citation Analysis]
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58 McHenry P, Wang WL, Devitt E, Kluesner N, Davisson VJ, McKee E, Schweitzer D, Helquist P, Tenniswood M. Iejimalides A and B inhibit lysosomal vacuolar H+-ATPase (V-ATPase) activity and induce S-phase arrest and apoptosis in MCF-7 cells. J Cell Biochem 2010;109:634-42. [PMID: 20039309 DOI: 10.1002/jcb.22438] [Cited by in Crossref: 9] [Cited by in F6Publishing: 22] [Article Influence: 0.7] [Reference Citation Analysis]
59 Thomas TP, Majoros I, Kotlyar A, Mullen D, Holl MM, Baker JR Jr. Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations. Biomacromolecules 2009;10:3207-14. [PMID: 19924846 DOI: 10.1021/bm900683r] [Cited by in Crossref: 92] [Cited by in F6Publishing: 100] [Article Influence: 7.1] [Reference Citation Analysis]
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