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For: Weng LP, Brown JL, Eng C. PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model. Hum Mol Genet. 2001;10:599-604. [PMID: 11230179 DOI: 10.1093/hmg/10.6.599] [Cited by in Crossref: 183] [Cited by in F6Publishing: 170] [Article Influence: 8.7] [Reference Citation Analysis]
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14 Dwivedi SKD, Samanta K, Yadav M, Jana AK, Singh AK, Chakravarti B, Mondal S, Konwar R, Trivedi AK, Chattopadhyay N, Sanyal S, Panda G. Amino acids derived benzoxazepines: Design, synthesis and antitumor activity. Bioorganic & Medicinal Chemistry Letters 2013;23:6816-21. [DOI: 10.1016/j.bmcl.2013.10.013] [Cited by in Crossref: 13] [Cited by in F6Publishing: 9] [Article Influence: 1.4] [Reference Citation Analysis]
15 Hang Y, Zheng YC, Cao Y, Li QS, Sui YJ. Suppression of gastric cancer growth by adenovirus-mediated transfer of the PTEN gene. World J Gastroenterol 2005; 11(15): 2224-2229 [PMID: 15818730 DOI: 10.3748/wjg.v11.i15.2224] [Cited by in CrossRef: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.5] [Reference Citation Analysis]
16 Martinez JD, Mo Q, Xu Y, Qin L, Li Y, Xu J. Common Genomic Aberrations in Mouse and Human Breast Cancers with Concurrent P53 Deficiency and Activated PTEN-PI3K-AKT Pathway. Int J Biol Sci 2022;18:229-41. [PMID: 34975329 DOI: 10.7150/ijbs.65763] [Reference Citation Analysis]
17 Tu T, Chen J, Chen L, Stiles BL. Dual-Specific Protein and Lipid Phosphatase PTEN and Its Biological Functions. Cold Spring Harb Perspect Med 2020;10:a036301. [PMID: 31548229 DOI: 10.1101/cshperspect.a036301] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
18 Davé V, Wert SE, Tanner T, Thitoff AR, Loudy DE, Whitsett JA. Conditional deletion of Pten causes bronchiolar hyperplasia. Am J Respir Cell Mol Biol 2008;38:337-45. [PMID: 17921358 DOI: 10.1165/rcmb.2007-0182OC] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 1.4] [Reference Citation Analysis]
19 Zhang H, Wang S, Cacalano N, Zhu H, Liu Q, Xie M, Kamrava M, Konecny G, Jin S. Oncogenic Y68 frame shift mutation of PTEN represents a mechanism of docetaxel resistance in endometrial cancer cell lines. Sci Rep 2019;9:2111. [PMID: 30765787 DOI: 10.1038/s41598-019-38585-9] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
20 Hlobilková A, Knillová J, Bártek J, Lukás J, Kolár Z. The mechanism of action of the tumour suppressor gene PTEN. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2003;147:19-25. [PMID: 15034601 DOI: 10.5507/bp.2003.003] [Cited by in Crossref: 40] [Cited by in F6Publishing: 17] [Article Influence: 2.9] [Reference Citation Analysis]
21 Whiteman DC, Zhou XP, Cummings MC, Pavey S, Hayward NK, Eng C. Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. Int J Cancer. 2002;99:63-67. [PMID: 11948493 DOI: 10.1002/ijc.10294] [Cited by in Crossref: 121] [Cited by in F6Publishing: 120] [Article Influence: 6.1] [Reference Citation Analysis]
22 Tan MH, Mester J, Peterson C, Yang Y, Chen JL, Rybicki LA, Milas K, Pederson H, Remzi B, Orloff MS, Eng C. A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands. Am J Hum Genet 2011;88:42-56. [PMID: 21194675 DOI: 10.1016/j.ajhg.2010.11.013] [Cited by in Crossref: 257] [Cited by in F6Publishing: 217] [Article Influence: 23.4] [Reference Citation Analysis]
23 Estaras M, Martinez R, García A, Ortiz-placin C, Iovanna JL, Santofimia-castaño P, Gonzalez A. Melatonin modulates metabolic adaptation of pancreatic stellate cells subjected to hypoxia. Biochemical Pharmacology 2022. [DOI: 10.1016/j.bcp.2022.115118] [Reference Citation Analysis]
24 Dillon LM, Miller TW. Therapeutic targeting of cancers with loss of PTEN function. Curr Drug Targets 2014;15:65-79. [PMID: 24387334 DOI: 10.2174/1389450114666140106100909] [Cited by in Crossref: 140] [Cited by in F6Publishing: 125] [Article Influence: 17.5] [Reference Citation Analysis]
25 Agrawal S, Pilarski R, Eng C. Different splicing defects lead to differential effects downstream of the lipid and protein phosphatase activities of PTEN. Human Molecular Genetics 2005;14:2459-68. [DOI: 10.1093/hmg/ddi246] [Cited by in Crossref: 28] [Cited by in F6Publishing: 25] [Article Influence: 1.6] [Reference Citation Analysis]
26 Ge H, Cao YY, Chen LQ, Wang YM, Chen ZF, Wen DG, Zhang XF, Guo W, Wang N, Li Y. PTEN polymorphisms and the risk of esophageal carcinoma and gastric cardiac carcinoma in a high incidence region of China. Dis Esophagus. 2008;21:409-415. [PMID: 19125794 DOI: 10.1111/j.1442-2050.2007.00786.x] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 1.5] [Reference Citation Analysis]
27 Mester J, Eng C. When overgrowth bumps into cancer: the PTEN-opathies. Am J Med Genet C Semin Med Genet 2013;163C:114-21. [PMID: 23613428 DOI: 10.1002/ajmg.c.31364] [Cited by in Crossref: 87] [Cited by in F6Publishing: 80] [Article Influence: 9.7] [Reference Citation Analysis]
28 Marino M, Acconcia F, Trentalance A. Biphasic estradiol-induced AKT phosphorylation is modulated by PTEN via MAP kinase in HepG2 cells. Mol Biol Cell. 2003;14:2583-2591. [PMID: 12808053 DOI: 10.1091/mbc.e02-09-0621] [Cited by in Crossref: 82] [Cited by in F6Publishing: 42] [Article Influence: 4.3] [Reference Citation Analysis]
29 Li X, Lin G, Wu B, Zhou X, Zhou K. Overexpression of PTEN induces cell growth arrest and apoptosis in human breast cancer ZR-75-1 cells. Acta Biochim Biophys Sin (Shanghai) 2007;39:745-50. [PMID: 17928923 DOI: 10.1111/j.1745-7270.2007.00337.x] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 0.9] [Reference Citation Analysis]
30 Capodanno A, Camerini A, Orlandini C, Baldini E, Resta ML, Bevilacqua G, Collecchi P. Dysregulated PI3K/Akt/PTEN pathway is a marker of a short disease-free survival in node-negative breast carcinoma. Hum Pathol. 2009;40:1408-1417. [PMID: 19428048 DOI: 10.1016/j.humpath.2009.02.005] [Cited by in Crossref: 36] [Cited by in F6Publishing: 36] [Article Influence: 2.8] [Reference Citation Analysis]
31 Nielsen-Preiss SM, Silva SR, Gillette JM. Role of PTEN and Akt in the regulation of growth and apoptosis in human osteoblastic cells. J Cell Biochem. 2003;90:964-975. [PMID: 14624456 DOI: 10.1002/jcb.10709] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 1.2] [Reference Citation Analysis]
32 Mereniuk TR, El Gendy MA, Mendes-Pereira AM, Lord CJ, Ghosh S, Foley E, Ashworth A, Weinfeld M. Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase. Mol Cancer Ther 2013;12:2135-44. [PMID: 23883586 DOI: 10.1158/1535-7163.MCT-12-1093] [Cited by in Crossref: 16] [Cited by in F6Publishing: 8] [Article Influence: 1.8] [Reference Citation Analysis]
33 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM. Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev 2006;20:1308-20. [PMID: 16702404 DOI: 10.1101/gad.1413606] [Cited by in Crossref: 89] [Cited by in F6Publishing: 94] [Article Influence: 5.6] [Reference Citation Analysis]
34 Peyrou M, Bourgoin L, Foti M. PTEN in liver diseases and cancer. World J Gastroenterol 2010; 16(37): 4627-4633 [PMID: 20872961 DOI: 10.3748/wjg.v16.i37.4627] [Cited by in CrossRef: 56] [Cited by in F6Publishing: 47] [Article Influence: 4.7] [Reference Citation Analysis]
35 Yokoyama A, Igarashi K, Sato T, Takagi K, Otsuka I M, Shishido Y, Baba T, Ito R, Kanno J, Ohkawa Y, Morohashi K, Sugawara A. Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex. J Biol Chem 2014;289:18152-62. [PMID: 24828497 DOI: 10.1074/jbc.M114.566448] [Cited by in Crossref: 25] [Cited by in F6Publishing: 18] [Article Influence: 3.1] [Reference Citation Analysis]
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37 Marsit CJ, Zheng S, Aldape K, Hinds PW, Nelson HH, Wiencke JK, Kelsey KT. PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Hum Pathol 2005;36:768-76. [PMID: 16084946 DOI: 10.1016/j.humpath.2005.05.006] [Cited by in Crossref: 173] [Cited by in F6Publishing: 174] [Article Influence: 10.2] [Reference Citation Analysis]
38 Steelman LS, Bertrand FE, Mccubrey JA. The complexity of PTEN: mutation, marker and potential target for therapeutic intervention. Expert Opinion on Therapeutic Targets 2005;8:537-50. [DOI: 10.1517/14728222.8.6.537] [Cited by in Crossref: 74] [Cited by in F6Publishing: 65] [Article Influence: 4.4] [Reference Citation Analysis]
39 Dupont J, Renou JP, Shani M, Hennighausen L, LeRoith D. PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium. J Clin Invest 2002;110:815-25. [PMID: 12235113 DOI: 10.1172/JCI13829] [Cited by in Crossref: 1] [Cited by in F6Publishing: 36] [Article Influence: 0.1] [Reference Citation Analysis]
40 Seo J, Lee HS, Ryoo S, Seo JH, Min BS, Lee JH. Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation. Eur J Pharmacol 2011;673:56-64. [PMID: 22040922 DOI: 10.1016/j.ejphar.2011.10.011] [Cited by in Crossref: 46] [Cited by in F6Publishing: 42] [Article Influence: 4.2] [Reference Citation Analysis]
41 Zhou H, Yu C, Kong L, Xu X, Yan J, Li Y, An T, Gong L, Gong Y, Zhu H, Zhang H, Yang X, Li Y. B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells. Oncogene 2019;38:3371-86. [PMID: 30635656 DOI: 10.1038/s41388-018-0674-5] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 3.7] [Reference Citation Analysis]
42 Zhou XP, Loukola A, Salovaara R, Nystrom-Lahti M, Peltomäki P, de la Chapelle A, Aaltonen LA, Eng C. PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers. Am J Pathol. 2002;161:439-447. [PMID: 12163369 DOI: 10.1016/s0002-9440(10)64200-9] [Cited by in Crossref: 131] [Cited by in F6Publishing: 71] [Article Influence: 6.6] [Reference Citation Analysis]
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44 Azimi A, Azimi A. Hypothesis: ROBOPHERA, a phosphatase and tensin homolog-targeted antineoplastic therapy. Anticancer Drugs 2017;28:369-75. [PMID: 28301379 DOI: 10.1097/CAD.0000000000000476] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
45 Louro AF, Paiva MA, Oliveira MR, Kasper KA, Alves PM, Gomes-Alves P, Serra M. Bioactivity and miRNome Profiling of Native Extracellular Vesicles in Human Induced Pluripotent Stem Cell-Cardiomyocyte Differentiation. Adv Sci (Weinh) 2022;9:e2104296. [PMID: 35322574 DOI: 10.1002/advs.202104296] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
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47 Al-Zaid T, Ditelberg JS, Prieto VG, Lev D, Luthra R, Davies MA, Diwan AH, Wang WL, Lazar AJ. Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors. J Cutan Pathol 2012;39:493-9. [PMID: 22486434 DOI: 10.1111/j.1600-0560.2012.01888.x] [Cited by in Crossref: 35] [Cited by in F6Publishing: 18] [Article Influence: 3.5] [Reference Citation Analysis]
48 Eng C. PTEN: One Gene, Many Syndromes. Hum Mutat 2003;22:183-98. [DOI: 10.1002/humu.10257] [Cited by in Crossref: 587] [Cited by in F6Publishing: 502] [Article Influence: 30.9] [Reference Citation Analysis]
49 Ravi Y, Selvendiran K, Meduru S, Citro L, Naidu S, Khan M, Rivera BK, Sai-Sudhakar CB, Kuppusamy P. Dysregulation of PTEN in cardiopulmonary vascular remodeling induced by pulmonary hypertension. Cell Biochem Biophys 2013;67:363-72. [PMID: 22205501 DOI: 10.1007/s12013-011-9332-z] [Cited by in Crossref: 19] [Cited by in F6Publishing: 21] [Article Influence: 2.4] [Reference Citation Analysis]
50 Jahanafrooz Z, Motamed N, Rinner B, Mokhtarzadeh A, Baradaran B. Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator. Life Sci 2018;213:236-47. [PMID: 30308184 DOI: 10.1016/j.lfs.2018.10.009] [Cited by in Crossref: 30] [Cited by in F6Publishing: 28] [Article Influence: 7.5] [Reference Citation Analysis]
51 Goto M, Iwase A, Ando H, Kurotsuchi S, Harata T, Kikkawa F. PTEN and Akt expression during growth of human ovarian follicles. J Assist Reprod Genet 2007;24:541-6. [PMID: 17999178 DOI: 10.1007/s10815-007-9156-3] [Cited by in Crossref: 35] [Cited by in F6Publishing: 37] [Article Influence: 2.3] [Reference Citation Analysis]
52 Leslie NR, Downes CP. PTEN: The down side of PI 3-kinase signalling. Cell Signal. 2002;14:285-295. [PMID: 11858936 DOI: 10.1016/S0898-6568(01)00234-0] [Cited by in Crossref: 284] [Cited by in F6Publishing: 109] [Article Influence: 14.2] [Reference Citation Analysis]
53 Renner O, Blanco-Aparicio C, Carnero A. Genetic modelling of the PTEN/AKT pathway in cancer research. Clin Transl Oncol 2008;10:618-27. [PMID: 18940742 DOI: 10.1007/s12094-008-0262-1] [Cited by in Crossref: 14] [Cited by in F6Publishing: 15] [Article Influence: 1.1] [Reference Citation Analysis]
54 Froment P, Bontoux M, Pisselet C, Monget P, Dupont J. PTEN expression in ovine granulosa cells increases during terminal follicular growth. FEBS Letters 2005;579:2376-82. [DOI: 10.1016/j.febslet.2005.03.036] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 1.2] [Reference Citation Analysis]
55 Puig I, Champeval D, De Santa Barbara P, Jaubert F, Lyonnet S, Larue L. Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. J Clin Invest 2009;119:3586-96. [PMID: 19884655 DOI: 10.1172/JCI39929] [Cited by in Crossref: 45] [Cited by in F6Publishing: 23] [Article Influence: 3.5] [Reference Citation Analysis]
56 Zhao C, Sun G, Li S, Lang MF, Yang S, Li W, Shi Y. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc Natl Acad Sci U S A 2010;107:1876-81. [PMID: 20133835 DOI: 10.1073/pnas.0908750107] [Cited by in Crossref: 265] [Cited by in F6Publishing: 268] [Article Influence: 22.1] [Reference Citation Analysis]
57 Li W, Sun G, Yang S, Qu Q, Nakashima K, Shi Y. Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain. Mol Endocrinol 2008;22:56-64. [PMID: 17901127 DOI: 10.1210/me.2007-0290] [Cited by in Crossref: 83] [Cited by in F6Publishing: 81] [Article Influence: 5.5] [Reference Citation Analysis]
58 Yanagawa N, Leduc C, Kohler D, Saieg MA, John T, Sykes J, Yoshimoto M, Pintilie M, Squire J, Shepherd FA, Tsao MS. Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma. J Thorac Oncol 2012;7:1513-21. [PMID: 22982652 DOI: 10.1097/JTO.0b013e3182641d4f] [Cited by in Crossref: 37] [Cited by in F6Publishing: 25] [Article Influence: 4.1] [Reference Citation Analysis]
59 Lee DY, Jeyapalan Z, Fang L, Yang J, Zhang Y, Yee AY, Li M, Du WW, Shatseva T, Yang BB. Expression of versican 3’-untranslated region modulates endogenous microRNA functions. PLoS One. 2010;5:e13599. [PMID: 21049042 DOI: 10.1371/journal.pone.0013599] [Cited by in Crossref: 101] [Cited by in F6Publishing: 101] [Article Influence: 8.4] [Reference Citation Analysis]
60 Lai JP, Dalton JT, Knoell DL. Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair. Br J Pharmacol 2007;152:1172-84. [PMID: 17922022 DOI: 10.1038/sj.bjp.0707501] [Cited by in Crossref: 40] [Cited by in F6Publishing: 41] [Article Influence: 2.7] [Reference Citation Analysis]
61 Ma X, Lin JS, Yang ZF, Li PY, Song DP. Effects of geldanamycin on PKB/Akt phosphorylation and cell cycle in human hepatoma HepG2 cells. Shijie Huaren Xiaohua Zazhi 2004; 12(8): 1793-1795 [DOI: 10.11569/wcjd.v12.i8.1793] [Reference Citation Analysis]
62 Yao D, Alexander CL, Quinn JA, Chan W, Wu H, Greenhalgh DA. Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21WAF-induced differentiation triggered by GSK3β inactivation and reduced AKT activity. Journal of Cell Science 2008;121:1758-69. [DOI: 10.1242/jcs.021147] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 1.0] [Reference Citation Analysis]
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