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For: Maione D, Di Carlo E, Li W, Musiani P, Modesti A, Peters M, Rose-John S, Della Rocca C, Tripodi M, Lazzaro D. Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver. EMBO J. 1998;17:5588-5597. [PMID: 9755159 DOI: 10.1093/emboj/17.19.5588] [Cited by in Crossref: 99] [Cited by in F6Publishing: 101] [Article Influence: 4.3] [Reference Citation Analysis]
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7 Cervello M, Notarbartolo M, Landino M, Cusimano A, Virruso L, Montalto G, D'alessandro N. Downregulation of wild-type β-catenin expression by interleukin 6 in human hepatocarcinoma HepG2 cells: a possible role in the growth-regulatory effects of the cytokine? European Journal of Cancer 2001;37:512-9. [DOI: 10.1016/s0959-8049(00)00421-4] [Cited by in Crossref: 12] [Cited by in F6Publishing: 5] [Article Influence: 0.6] [Reference Citation Analysis]
8 Braun O, Dewitz C, Möller-hackbarth K, Scheller J, Schiffelholz T, Baier PC, Rose-john S. Effects of Blockade of Peripheral Interleukin-6 Trans-Signaling on Hippocampus-Dependent and Independent Memory in Mice. Journal of Interferon & Cytokine Research 2013;33:254-60. [DOI: 10.1089/jir.2012.0096] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
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11 Rebouissou S, Amessou M, Couchy G, Poussin K, Imbeaud S, Pilati C, Izard T, Balabaud C, Bioulac-Sage P, Zucman-Rossi J. Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. Nature. 2009;457:200-204. [PMID: 19020503 DOI: 10.1038/nature07475] [Cited by in Crossref: 354] [Cited by in F6Publishing: 305] [Article Influence: 27.2] [Reference Citation Analysis]
12 Ohtani T, Ishihara K, Atsumi T, Yoshida Y, Nishida K, Narimatsu M, Shirogane T, Hibi M, Hirano T. gp130-mediated signalling as a therapeutic target. Emerging Therapeutic Targets 2005;4:459-79. [DOI: 10.1517/14728222.4.4.459] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.1] [Reference Citation Analysis]
13 Labbozzetta M, Notarbartolo M, Poma P, Giannitrapani L, Cervello M, Montalto G, D’Alessandro N. Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma. Ann N Y Acad Sci. 2006;1089:268-275. [PMID: 17261774 DOI: 10.1196/annals.1386.014] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
14 Howlett M, Menheniott TR, Judd LM, Giraud AS. Cytokine signalling via gp130 in gastric cancer. Biochim Biophys Acta 2009;1793:1623-33. [PMID: 19665497 DOI: 10.1016/j.bbamcr.2009.07.009] [Cited by in Crossref: 43] [Cited by in F6Publishing: 40] [Article Influence: 3.6] [Reference Citation Analysis]
15 Taniguchi K, Karin M. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Seminars in Immunology. 2014;26:54-74. [PMID: 24552665 DOI: 10.1016/j.smim.2014.01.001] [Cited by in Crossref: 319] [Cited by in F6Publishing: 275] [Article Influence: 45.6] [Reference Citation Analysis]
16 Bajari TM, Strasser V, Nimpf J, Schneider WJ. A model for modulation of leptin activity by association with clusterin. FASEB J 2003;17:1505-7. [PMID: 12824284 DOI: 10.1096/fj.02-1106fje] [Cited by in Crossref: 38] [Cited by in F6Publishing: 32] [Article Influence: 2.1] [Reference Citation Analysis]
17 Malchow S, Thaiss W, Jänner N, Waetzig GH, Gewiese-rabsch J, Garbers C, Yamamoto K, Rose-john S, Scheller J. Essential role of neutrophil mobilization in concanavalin A-induced hepatitis is based on classic IL-6 signaling but not on IL-6 trans-signaling. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2011;1812:290-301. [DOI: 10.1016/j.bbadis.2010.11.009] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 1.7] [Reference Citation Analysis]
18 Moran DM, Mattocks MA, Cahill PA, Koniaris LG, McKillop IH. Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway. J Surg Res 2008;147:23-33. [PMID: 17574577 DOI: 10.1016/j.jss.2007.04.022] [Cited by in Crossref: 40] [Cited by in F6Publishing: 34] [Article Influence: 2.9] [Reference Citation Analysis]
19 Moran DM, Mayes N, Koniaris LG, Cahill PA, McKillop IH. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. Liver Int. 2005;25:445-457. [PMID: 15780071 DOI: 10.1111/j.1478-3231.2005.01083.x] [Cited by in Crossref: 18] [Cited by in F6Publishing: 20] [Article Influence: 1.1] [Reference Citation Analysis]
20 Yang XP, Schaper F, Teubner A, Lammert F, Heinrich PC, Matern S, Siewert E. Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo. J Hepatol. 2005;43:704-710. [PMID: 16040151 DOI: 10.1016/j.jhep.2005.02.048] [Cited by in Crossref: 34] [Cited by in F6Publishing: 31] [Article Influence: 2.1] [Reference Citation Analysis]
21 Peters M, Blinn G, Jostock T, Schirmacher P, Büschenfelde KMZ, Galle PR, Rose–john S. Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration. Gastroenterology 2000;119:1663-71. [DOI: 10.1053/gast.2000.20236] [Cited by in Crossref: 89] [Cited by in F6Publishing: 82] [Article Influence: 4.2] [Reference Citation Analysis]
22 Galun E, Rose-john S. The Regenerative Activity of Interleukin-6. In: Ghezzi P, Cerami A, editors. Tissue-Protective Cytokines. Totowa: Humana Press; 2013. pp. 59-77. [DOI: 10.1007/978-1-62703-308-4_4] [Cited by in Crossref: 20] [Cited by in F6Publishing: 14] [Article Influence: 2.5] [Reference Citation Analysis]
23 Croquelois A, Blindenbacher A, Terracciano L, Wang X, Langer I, Radtke F, Heim MH. Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. Hepatology. 2005;41:487-496. [PMID: 15723439 DOI: 10.1002/hep.20571] [Cited by in Crossref: 79] [Cited by in F6Publishing: 70] [Article Influence: 4.9] [Reference Citation Analysis]
24 Anderson SP, Dunn CS, Cattley RC, Corton J. Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFα signaling. Carcinogenesis 2001;22:1843-51. [DOI: 10.1093/carcin/22.11.1843] [Cited by in Crossref: 25] [Cited by in F6Publishing: 20] [Article Influence: 1.3] [Reference Citation Analysis]
25 Zvibel I, Brill S, Kariv R, Traister A, Golan T, Chebath J, Halpern Z, Revel M, Oren R. Chimeric molecule IL-6/soluble IL-6 receptor is a potent mitogen for fetal hepatocytes. J Cell Physiol 2004;200:245-52. [DOI: 10.1002/jcp.20019] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
26 Leu JI, Crissey MA, Leu JP, Ciliberto G, Taub R. Interleukin-6-induced STAT3 and AP-1 amplify hepatocyte nuclear factor 1-mediated transactivation of hepatic genes, an adaptive response to liver injury. Mol Cell Biol. 2001;21:414-424. [PMID: 11134330 DOI: 10.1128/mcb.21.2.414-424.2001] [Cited by in Crossref: 101] [Cited by in F6Publishing: 36] [Article Influence: 5.1] [Reference Citation Analysis]
27 Sabrautzki S, Janas E, Lorenz-Depiereux B, Calzada-Wack J, Aguilar-Pimentel JA, Rathkolb B, Adler T, Cohrs C, Hans W, Diener S, Fuchs H, Gailus-Durner V, Busch DH, Höfler H, Ollert M, Strom TM, Wolf E, Neff F, Hrabě de Angelis M. An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease. Am J Pathol 2013;183:352-68. [PMID: 23791841 DOI: 10.1016/j.ajpath.2013.04.027] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 1.5] [Reference Citation Analysis]
28 Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 2004;5:836-47. [DOI: 10.1038/nrm1489] [Cited by in Crossref: 1020] [Cited by in F6Publishing: 913] [Article Influence: 60.0] [Reference Citation Analysis]
29 Rose-John S. The soluble interleukin-6 receptor and related proteins. Best Pract Res Clin Endocrinol Metab 2015;29:787-97. [PMID: 26522462 DOI: 10.1016/j.beem.2015.07.001] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 3.8] [Reference Citation Analysis]
30 Kuo M, Chuang S, Lin M, Yang S. The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogene 2001;20:677-85. [DOI: 10.1038/sj.onc.1204140] [Cited by in Crossref: 111] [Cited by in F6Publishing: 96] [Article Influence: 5.6] [Reference Citation Analysis]
31 Fazel Modares N, Polz R, Haghighi F, Lamertz L, Behnke K, Zhuang Y, Kordes C, Häussinger D, Sorg UR, Pfeffer K, Floss DM, Moll JM, Piekorz RP, Ahmadian MR, Lang PA, Scheller J. IL-6 Trans-signaling Controls Liver Regeneration After Partial Hepatectomy. Hepatology 2019;70:2075-91. [PMID: 31100194 DOI: 10.1002/hep.30774] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 12.0] [Reference Citation Analysis]
32 Soresi M, Giannitrapani L, D'Antona F, Florena AM, La Spada E, Terranova A, Cervello M, D'Alessandro N, Montalto G. Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma. World J Gastroenterol 2006;12:2563-8. [PMID: 16688802 DOI: 10.3748/wjg.v12.i16.2563] [Cited by in CrossRef: 65] [Cited by in F6Publishing: 67] [Article Influence: 4.3] [Reference Citation Analysis]
33 Schmidt-Arras D, Rose-John S. IL-6 pathway in the liver: From physiopathology to therapy. J Hepatol. 2016;64:1403-1415. [PMID: 26867490 DOI: 10.1016/j.jhep.2016.02.004] [Cited by in Crossref: 305] [Cited by in F6Publishing: 276] [Article Influence: 61.0] [Reference Citation Analysis]
34 Galun E, Zeira E, Pappo O, Peters M, Rose-John S. Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury. FASEB J. 2000;14:1979-1987. [PMID: 11023982 DOI: 10.1096/fj.99-0913com] [Cited by in Crossref: 87] [Cited by in F6Publishing: 71] [Article Influence: 4.1] [Reference Citation Analysis]
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36 Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls. Toxicol Appl Pharmacol 2002;179:172-84. [PMID: 11906247 DOI: 10.1006/taap.2001.9360] [Cited by in Crossref: 84] [Cited by in F6Publishing: 73] [Article Influence: 4.4] [Reference Citation Analysis]
37 Nakagawa H, Maeda S. Inflammation- and stress-related signaling pathways in hepatocarcinogenesis. World J Gastroenterol. 2012;18:4071-4081. [PMID: 22919237 DOI: 10.3748/wjg.v18.i31.4071] [Cited by in CrossRef: 83] [Cited by in F6Publishing: 75] [Article Influence: 10.4] [Reference Citation Analysis]
38 Zimmers TA, McKillop IH, Pierce RH, Yoo JY, Koniaris LG. Massive liver growth in mice induced by systemic interleukin 6 administration. Hepatology. 2003;38:326-334. [PMID: 12883476 DOI: 10.1053/jhep.2003.50318] [Cited by in Crossref: 101] [Cited by in F6Publishing: 97] [Article Influence: 5.6] [Reference Citation Analysis]
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42 Ronot M, Kerbaol A, Rautou P, Brancatelli G, Bedossa P, Cazals-hatem D, Valla D, Vilgrain V. Acute extrahepatic infectious or inflammatory diseases are a cause of transient mosaic pattern on CT and MR imaging related to sinusoidal dilatation of the liver. Eur Radiol 2016;26:3094-101. [DOI: 10.1007/s00330-015-4124-2] [Cited by in Crossref: 15] [Cited by in F6Publishing: 6] [Article Influence: 2.5] [Reference Citation Analysis]
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50 Ohbayashi N, Kawakami S, Muromoto R, Togi S, Ikeda O, Kamitani S, Sekine Y, Honjoh T, Matsuda T. The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. Biochem Biophys Res Commun 2008;371:823-8. [PMID: 18474224 DOI: 10.1016/j.bbrc.2008.04.179] [Cited by in Crossref: 13] [Cited by in F6Publishing: 17] [Article Influence: 1.0] [Reference Citation Analysis]
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52 Migita K, Abiru S, Maeda Y, Daikoku M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K. Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection. Hum Immunol. 2006;67:27-32. [PMID: 16698422 DOI: 10.1016/j.humimm.2006.02.025] [Cited by in Crossref: 37] [Cited by in F6Publishing: 32] [Article Influence: 2.5] [Reference Citation Analysis]
53 Scheller J, Grötzinger J, Rose-john S. Updating interleukin-6 classic- and trans-signaling. Signal Transduction 2006;6:240-59. [DOI: 10.1002/sita.200600086] [Cited by in Crossref: 37] [Cited by in F6Publishing: 19] [Article Influence: 2.5] [Reference Citation Analysis]
54 Zhou Y, Xu J, Liu Y, Li J, Chang C, Xu C. Rat hepatocytes weighted gene co-expression network analysis identifies specific modules and hub genes related to liver regeneration after partial hepatectomy. PLoS One 2014;9:e94868. [PMID: 24743545 DOI: 10.1371/journal.pone.0094868] [Cited by in Crossref: 15] [Cited by in F6Publishing: 8] [Article Influence: 2.1] [Reference Citation Analysis]
55 Bard-Chapeau EA, Yuan J, Droin N, Long S, Zhang EE, Nguyen TV, Feng GS. Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection. Mol Cell Biol 2006;26:4664-74. [PMID: 16738330 DOI: 10.1128/MCB.02253-05] [Cited by in Crossref: 69] [Cited by in F6Publishing: 45] [Article Influence: 4.6] [Reference Citation Analysis]
56 Lukashevich IS, Rodas JD, Tikhonov II, Zapata JC, Yang Y, Djavani M, Salvato MS. LCMV-mediated hepatitis in rhesus macaques: WE but not ARM strain activates hepatocytes and induces liver regeneration. Arch Virol 2004;149:2319-36. [PMID: 15338320 DOI: 10.1007/s00705-004-0385-9] [Cited by in Crossref: 37] [Cited by in F6Publishing: 31] [Article Influence: 2.2] [Reference Citation Analysis]
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