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For: Tyagi A, Agarwal C, Harrison G, Glode LM, Agarwal R. Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages. Carcinogenesis. 2004;25:1711-1720. [PMID: 15117815 DOI: 10.1093/carcin/bgh180] [Cited by in Crossref: 87] [Cited by in F6Publishing: 79] [Article Influence: 4.8] [Reference Citation Analysis]
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13 Sabarwal A, Agarwal R, Singh RP. Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells. Mol Carcinog 2017;56:499-514. [PMID: 27254419 DOI: 10.1002/mc.22512] [Cited by in Crossref: 38] [Cited by in F6Publishing: 33] [Article Influence: 6.3] [Reference Citation Analysis]
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17 Momeny M, Malehmir M, Zakidizaji M, Ghasemi R, Ghadimi H, Shokrgozar MA, Emami AH, Nafissi S, Ghavamzadeh A, Ghaffari SH. Silibinin inhibits invasive properties of human glioblastoma U87MG cells through suppression of cathepsin B and nuclear factor kappa B-mediated induction of matrix metalloproteinase 9. Anti-Cancer Drugs 2010;21:252-60. [DOI: 10.1097/cad.0b013e3283340cd7] [Cited by in Crossref: 24] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis]
18 Yun DG, Lee DG. Silibinin triggers yeast apoptosis related to mitochondrial Ca2+ influx in Candida albicans. The International Journal of Biochemistry & Cell Biology 2016;80:1-9. [DOI: 10.1016/j.biocel.2016.09.008] [Cited by in Crossref: 42] [Cited by in F6Publishing: 39] [Article Influence: 7.0] [Reference Citation Analysis]
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24 Ge Y, Zhang Y, Chen Y, Li Q, Chen J, Dong Y, Shi W. Silibinin causes apoptosis and cell cycle arrest in some human pancreatic cancer cells. Int J Mol Sci 2011;12:4861-71. [PMID: 21954330 DOI: 10.3390/ijms12084861] [Cited by in Crossref: 22] [Cited by in F6Publishing: 23] [Article Influence: 2.0] [Reference Citation Analysis]
25 Tuli HS, Mittal S, Aggarwal D, Parashar G, Parashar NC, Upadhyay SK, Barwal TS, Jain A, Kaur G, Savla R, Sak K, Kumar M, Varol M, Iqubal A, Sharma AK. Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance. Semin Cancer Biol 2021;73:196-218. [PMID: 33130037 DOI: 10.1016/j.semcancer.2020.09.014] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
26 Pravettoni A, Mornati O, Martini PG, Marino M, Colciago A, Celotti F, Motta M, Negri-Cesi P. Estrogen receptor beta (ERbeta) and inhibition of prostate cancer cell proliferation: studies on the possible mechanism of action in DU145 cells. Mol Cell Endocrinol 2007;263:46-54. [PMID: 17023111 DOI: 10.1016/j.mce.2006.08.008] [Cited by in Crossref: 52] [Cited by in F6Publishing: 55] [Article Influence: 3.3] [Reference Citation Analysis]
27 Jahanafrooz Z, Motamed N, Rinner B, Mokhtarzadeh A, Baradaran B. Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator. Life Sci 2018;213:236-47. [PMID: 30308184 DOI: 10.1016/j.lfs.2018.10.009] [Cited by in Crossref: 30] [Cited by in F6Publishing: 28] [Article Influence: 7.5] [Reference Citation Analysis]
28 Sameri S, Mohammadi C, Mehrabani M, Najafi R. Targeting the hallmarks of cancer: the effects of silibinin on proliferation, cell death, angiogenesis, and migration in colorectal cancer. BMC Complement Med Ther 2021;21:160. [PMID: 34059044 DOI: 10.1186/s12906-021-03330-1] [Reference Citation Analysis]
29 Özer N, Bülbüloğlu E, Yormaz S, Ece İ. Evaluation of silybum marinaum efficacy on University of Wisconsin and histidine-tryptophan-ketoglutarate solutions latter the damage of the perfused liver. Acta Cir Bras 2017;32:407-17. [PMID: 28700002 DOI: 10.1590/s0102-865020170060000001] [Reference Citation Analysis]
30 Parry JW, Cheng Z, Moore J, Yu LL. Fatty Acid Composition, Antioxidant Properties, and Antiproliferative Capacity of Selected Cold-Pressed Seed Flours. J Am Oil Chem Soc 2008;85:457-64. [DOI: 10.1007/s11746-008-1207-0] [Cited by in Crossref: 29] [Cited by in F6Publishing: 18] [Article Influence: 2.1] [Reference Citation Analysis]
31 Momeny M, Ghasemi R, Valenti G, Miranda M, Zekri A, Zarrinrad G, Javadikooshesh S, Yaghmaie M, Alimoghaddam K, Ghavamzadeh A, Ghaffari SH. Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway. Tumor Biol 2016;37:3913-23. [DOI: 10.1007/s13277-015-4220-6] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 1.4] [Reference Citation Analysis]
32 Yassin NYS, AbouZid SF, El-Kalaawy AM, Ali TM, Almehmadi MM, Ahmed OM. Silybum marianum total extract, silymarin and silibinin abate hepatocarcinogenesis and hepatocellular carcinoma growth via modulation of the HGF/c-Met, Wnt/β-catenin, and PI3K/Akt/mTOR signaling pathways. Biomed Pharmacother 2021;145:112409. [PMID: 34781148 DOI: 10.1016/j.biopha.2021.112409] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
33 Li XQ, Bai YL, Zhang DL, Jiao HS, He RX. Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest. Onco Targets Ther 2018;11:4395-405. [PMID: 30100745 DOI: 10.2147/OTT.S166018] [Cited by in Crossref: 1] [Article Influence: 0.3] [Reference Citation Analysis]
34 Karthi N, Kalaiyarasu T, Kandakumar S, Mariyappan P, Manju V. Pelargonidin induces apoptosis and cell cycle arrest via a mitochondria mediated intrinsic apoptotic pathway in HT29 cells. RSC Adv 2016;6:45064-76. [DOI: 10.1039/c5ra20984f] [Cited by in Crossref: 13] [Article Influence: 2.2] [Reference Citation Analysis]
35 Kaur M, Agarwal R. Silymarin and epithelial cancer chemoprevention: how close we are to bedside? Toxicol Appl Pharmacol 2007;224:350-9. [PMID: 17184801 DOI: 10.1016/j.taap.2006.11.011] [Cited by in Crossref: 54] [Cited by in F6Publishing: 50] [Article Influence: 3.4] [Reference Citation Analysis]
36 Hogan FS, Krishnegowda NK, Mikhailova M, Kahlenberg MS. Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer. J Surg Res. 2007;143:58-65. [PMID: 17950073 DOI: 10.1016/j.jss.2007.03.080] [Cited by in Crossref: 106] [Cited by in F6Publishing: 101] [Article Influence: 7.1] [Reference Citation Analysis]
37 Yang X, Li X, An L, Bai B, Chen J. Silibinin induced the apoptosis of Hep-2 cells via oxidative stress and down-regulating survivin expression. Eur Arch Otorhinolaryngol 2013;270:2289-97. [PMID: 23580032 DOI: 10.1007/s00405-013-2444-x] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.7] [Reference Citation Analysis]
38 Choi ES, Oh S, Jang B, Yu HJ, Shin JA, Cho NP, Yang IH, Won DH, Kwon HJ, Hong SD, Cho SD. Silymarin and its active component silibinin act as novel therapeutic alternatives for salivary gland cancer by targeting the ERK1/2-Bim signaling cascade. Cell Oncol (Dordr) 2017;40:235-46. [PMID: 28401485 DOI: 10.1007/s13402-017-0318-8] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 2.6] [Reference Citation Analysis]
39 Zhang Y, Yang DH, Zhang YT, Chen XM, Li LL, Cai SQ. Biotransformation on the flavonolignan constituents of Silybi Fructus by an intestinal bacterial strain Eubacterium limosum ZL-II. Fitoterapia 2014;92:61-71. [PMID: 24125915 DOI: 10.1016/j.fitote.2013.10.001] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.9] [Reference Citation Analysis]
40 Zhang X, Liu J, Zhang P, Dai L, Wu Z, Wang L, Cao M, Jiang J. Silibinin induces G1 arrest, apoptosis and JNK/SAPK upregulation in SW1990 human pancreatic cancer cells. Oncol Lett 2018;15:9868-76. [PMID: 29805688 DOI: 10.3892/ol.2018.8541] [Cited by in Crossref: 5] [Cited by in F6Publishing: 8] [Article Influence: 1.3] [Reference Citation Analysis]
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42 Pljesa-ercegovac M, Savic-radojevic A, Dragicevic D, Mimic-oka J, Matic M, Sasic T, Pekmezovic T, Vuksanovic A, Simic T. Enhanced GSTP1 expression in transitional cell carcinoma of urinary bladder is associated with altered apoptotic pathways. Urologic Oncology: Seminars and Original Investigations 2011;29:70-7. [DOI: 10.1016/j.urolonc.2008.10.019] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.3] [Reference Citation Analysis]
43 Colombo V, Lupi M, Falcetta F, Forestieri D, D'Incalci M, Ubezio P. Chemotherapeutic activity of silymarin combined with doxorubicin or paclitaxel in sensitive and multidrug-resistant colon cancer cells. Cancer Chemother Pharmacol 2011;67:369-79. [PMID: 20431887 DOI: 10.1007/s00280-010-1335-8] [Cited by in Crossref: 26] [Cited by in F6Publishing: 17] [Article Influence: 2.2] [Reference Citation Analysis]
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45 Sameri S, Saidijam M, Bahreini F, Najafi R. Cancer Chemopreventive Activities of Silibinin on Colorectal Cancer through Regulation of E-Cadherin/β-Catenin Pathway. Nutr Cancer 2021;73:1389-99. [PMID: 32748663 DOI: 10.1080/01635581.2020.1800764] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 2.5] [Reference Citation Analysis]
46 Kim S, Kim K, Yu S, Park S, Choi H, Ji J, Ahn S. Autophagy inhibition enhances silibinin-induced apoptosis by regulating reactive oxygen species production in human prostate cancer PC-3 cells. Biochemical and Biophysical Research Communications 2015;468:151-6. [DOI: 10.1016/j.bbrc.2015.10.143] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 3.0] [Reference Citation Analysis]
47 Woo J, Shin S, Cho E, Ryu D, Garandeau D, Chajra H, Fréchet M, Park D, Jung E. Senotherapeutic-like effect of Silybum marianum flower extract revealed on human skin cells. PLoS One 2021;16:e0260545. [PMID: 34914725 DOI: 10.1371/journal.pone.0260545] [Reference Citation Analysis]
48 Mateen S, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators. Mol Carcinog. 2010;49:247-258. [PMID: 19908243 DOI: 10.1002/mc.20595] [Cited by in Crossref: 54] [Cited by in F6Publishing: 56] [Article Influence: 4.5] [Reference Citation Analysis]
49 Guo D, Ye Y, Qi J, Xu L, Zhang L, Tan X, Tan Z, Yu X, Zhang Y, Ma Y, Li Y. MicroRNA-195a-5p inhibits mouse medullary thymic epithelial cells proliferation by directly targeting Smad7. Acta Biochim Biophys Sin (Shanghai) 2016;48:290-7. [PMID: 26837421 DOI: 10.1093/abbs/gmv136] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 2.0] [Reference Citation Analysis]
50 Gu M, Dhanalakshmi S, Mohan S, Singh RP, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin. Carcinogenesis 2005;26:1404-13. [PMID: 15831527 DOI: 10.1093/carcin/bgi096] [Cited by in Crossref: 47] [Cited by in F6Publishing: 40] [Article Influence: 2.8] [Reference Citation Analysis]
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52 Wu K, Ning Z, Zeng J, Fan J, Zhou J, Zhang T, Zhang L, Chen Y, Gao Y, Wang B, Guo P, Li L, Wang X, He D. Silibinin inhibits β-catenin/ZEB1 signaling and suppresses bladder cancer metastasis via dual-blocking epithelial-mesenchymal transition and stemness. Cell Signal 2013;25:2625-33. [PMID: 24012496 DOI: 10.1016/j.cellsig.2013.08.028] [Cited by in Crossref: 64] [Cited by in F6Publishing: 65] [Article Influence: 7.1] [Reference Citation Analysis]
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58 Milić N, Milošević N, Suvajdžić L, Žarkov M, Abenavoli L. New Therapeutic Potentials of Milk Thistle ( Silybum marianum ). Natural Product Communications 2013;8:1934578X1300801. [DOI: 10.1177/1934578x1300801236] [Cited by in Crossref: 9] [Article Influence: 1.0] [Reference Citation Analysis]
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