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For: Singh RP, Tyagi AK, Zhao J, Agarwal R. Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis. Carcinogenesis. 2002;23:499-510. [PMID: 11895866 DOI: 10.1093/carcin/23.3.499] [Cited by in Crossref: 95] [Cited by in F6Publishing: 87] [Article Influence: 4.8] [Reference Citation Analysis]
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22 Kim EJ, Lee MY, Jeon YJ. Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway. Korean J Physiol Pharmacol 2015;19:211-8. [PMID: 25954125 DOI: 10.4196/kjpp.2015.19.3.211] [Cited by in Crossref: 32] [Cited by in F6Publishing: 28] [Article Influence: 4.6] [Reference Citation Analysis]
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25 Varga Z, Ujhelyi L, Kiss A, Balla J, Czompa A, Antus S. Effect of silybin on phorbol myristate actetate-induced protein kinase C translocation, NADPH oxidase activity and apoptosis in human neutrophils. Phytomedicine 2004;11:206-12. [PMID: 15070174 DOI: 10.1078/0944-7113-00358] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 0.7] [Reference Citation Analysis]
26 Huang Q, Wu L, Tashiro S, Onodera S, Li L, Ikejima T. Silymarin augments human cervical cancer HeLa cell apoptosis via P38/JNK MAPK pathways in serum-free medium. Journal of Asian Natural Products Research 2005;7:701-9. [DOI: 10.1080/1028602042000324862] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 1.1] [Reference Citation Analysis]
27 Abouzid S, Ahmed OM. Silymarin Flavonolignans. Elsevier; 2013. pp. 469-84. [DOI: 10.1016/b978-0-444-59603-1.00014-x] [Cited by in Crossref: 10] [Article Influence: 1.1] [Reference Citation Analysis]
28 Kaur M, Agarwal R. Silymarin and epithelial cancer chemoprevention: how close we are to bedside? Toxicol Appl Pharmacol 2007;224:350-9. [PMID: 17184801 DOI: 10.1016/j.taap.2006.11.011] [Cited by in Crossref: 54] [Cited by in F6Publishing: 50] [Article Influence: 3.4] [Reference Citation Analysis]
29 Youn CK, Park SJ, Lee MY, Cha MJ, Kim OH, You HJ, Chang IY, Yoon SP, Jeon YJ. Silibinin Inhibits LPS-Induced Macrophage Activation by Blocking p38 MAPK in RAW 264.7 Cells. Biomol Ther (Seoul) 2013;21:258-63. [PMID: 24244809 DOI: 10.4062/biomolther.2013.044] [Cited by in Crossref: 38] [Cited by in F6Publishing: 38] [Article Influence: 4.2] [Reference Citation Analysis]
30 Chen P, Hsieh Y, Chiou H, Chu S. Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways. Chemico-Biological Interactions 2005;156:141-50. [DOI: 10.1016/j.cbi.2005.08.005] [Cited by in Crossref: 141] [Cited by in F6Publishing: 132] [Article Influence: 8.3] [Reference Citation Analysis]
31 Jeong JC, Kim MS, Kim TH, Kim YK. Kaempferol Induces Cell Death Through ERK and Akt-Dependent Down-Regulation of XIAP and Survivin in Human Glioma Cells. Neurochem Res 2009;34:991-1001. [DOI: 10.1007/s11064-008-9868-5] [Cited by in Crossref: 52] [Cited by in F6Publishing: 43] [Article Influence: 3.7] [Reference Citation Analysis]
32 Rigby CM, Roy S, Deep G, Guillermo-Lagae R, Jain AK, Dhar D, Orlicky DJ, Agarwal C, Agarwal R. Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis. Carcinogenesis 2017;38:40-50. [PMID: 27729375 DOI: 10.1093/carcin/bgw106] [Cited by in Crossref: 22] [Cited by in F6Publishing: 20] [Article Influence: 3.7] [Reference Citation Analysis]
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35 Tyagi AK, Agarwal C, Singh RP, Shroyer KR, Glode LM, Agarwal R. Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells. Biochem Biophys Res Commun. 2003;312:1178-1184. [PMID: 14651997 DOI: 10.1016/j.bbrc.2003.11.038] [Cited by in Crossref: 42] [Cited by in F6Publishing: 37] [Article Influence: 2.3] [Reference Citation Analysis]
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39 Rigby C, Deep G, Jain A, Orlicky DJ, Agarwal C, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma. Mol Carcinog 2019;58:1260-71. [PMID: 30912211 DOI: 10.1002/mc.23008] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
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41 Yassin NYS, AbouZid SF, El-Kalaawy AM, Ali TM, Almehmadi MM, Ahmed OM. Silybum marianum total extract, silymarin and silibinin abate hepatocarcinogenesis and hepatocellular carcinoma growth via modulation of the HGF/c-Met, Wnt/β-catenin, and PI3K/Akt/mTOR signaling pathways. Biomed Pharmacother 2021;145:112409. [PMID: 34781148 DOI: 10.1016/j.biopha.2021.112409] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
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44 Kim SH, Choo GS, Yoo ES, Woo JS, Lee JH, Han SH, Jung SH, Kim HJ, Jung JY. Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis. Oncol Lett 2021;21:492. [PMID: 33968208 DOI: 10.3892/ol.2021.12753] [Reference Citation Analysis]
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51 Comelli MC, Mengs U, Schneider C, Prosdocimi M. Toward the Definition of the Mechanism of Action of Silymarin: Activities Related to Cellular Protection From Toxic Damage Induced by Chemotherapy. Integr Cancer Ther 2007;6:120-9. [DOI: 10.1177/1534735407302349] [Cited by in Crossref: 72] [Cited by in F6Publishing: 67] [Article Influence: 12.0] [Reference Citation Analysis]
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53 Abdollahi P, Ebrahimi M, Motamed N, Samani FS. Silibinin affects tumor cell growth because of reduction of stemness properties and induction of apoptosis in 2D and 3D models of MDA-MB-468. Anticancer Drugs 2015;26:487-97. [PMID: 25603020 DOI: 10.1097/CAD.0000000000000205] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 1.1] [Reference Citation Analysis]
54 Lah JJ, Cui W, Hu KQ. Effects and mechanisms of silibinin on human hepatoma cell lines. World J Gastroenterol 2007; 13(40): 5299-5305 [PMID: 17879397 DOI: 10.3748/wjg.v13.i40.5299] [Cited by in CrossRef: 65] [Cited by in F6Publishing: 58] [Article Influence: 4.3] [Reference Citation Analysis]
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57 Hoh CSL, Boocock DJ, Marczylo TH, Brown VA, Cai H, Steward WP, Berry DP, Gescher AJ. Quantitation of Silibinin, a Putative Cancer Chemopreventive Agent Derived from Milk Thistle ( Silybum marianum ), in Human Plasma by High-Performance Liquid Chromatography and Identification of Possible Metabolites. J Agric Food Chem 2007;55:2532-5. [DOI: 10.1021/jf063156c] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 1.7] [Reference Citation Analysis]
58 Aghemo A, Alekseeva OP, Angelico F, Bakulin IG, Bakulina NV, Bordin D, Bueverov AO, Drapkina OM, Gillessen A, Kagarmanova EM, Korochanskaya NV, Kucheryavii UA, Lazebnik LB, Livzan MA, Maev IV, Martynov AI, Osipenko MF, Sas EI, Starodubova A, Uspensky YP, Vinnitskaya EV, Yakovenko EP, Yakovlev AA. Role of silymarin as antioxidant in clinical management of chronic liver diseases: a narrative review. Annals of Medicine 2022;54:1548-60. [DOI: 10.1080/07853890.2022.2069854] [Reference Citation Analysis]
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