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For: Stennicke HR, Deveraux QL, Humke EW, Reed JC, Dixit VM, Salvesen GS. Caspase-9 can be activated without proteolytic processing. J Biol Chem. 1999;274:8359-8362. [PMID: 10085063 DOI: 10.1074/jbc.274.13.8359] [Cited by in Crossref: 344] [Cited by in F6Publishing: 319] [Article Influence: 15.0] [Reference Citation Analysis]
Number Citing Articles
1 Bibo-verdugo B, Salvesen GS. Caspase mechanisms in the regulation of inflammation. Molecular Aspects of Medicine 2022. [DOI: 10.1016/j.mam.2022.101085] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 5.0] [Reference Citation Analysis]
2 Araya LE, Soni IV, Hardy JA, Julien O. Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling. ACS Chem Biol 2021;16:2280-96. [PMID: 34553588 DOI: 10.1021/acschembio.1c00456] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
3 Sagwal SK, Bekeschus S. ROS Pleiotropy in Melanoma and Local Therapy with Physical Modalities. Oxid Med Cell Longev 2021;2021:6816214. [PMID: 34777692 DOI: 10.1155/2021/6816214] [Cited by in F6Publishing: 3] [Reference Citation Analysis]
4 Soni IV, Hardy JA. Caspase-9 Activation of Procaspase-3 but Not Procaspase-6 Is Based on the Local Context of Cleavage Site Motifs and on Sequence. Biochemistry 2021;60:2824-35. [PMID: 34472839 DOI: 10.1021/acs.biochem.1c00459] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
5 Behl T, Sharma A, Sharma L, Sehgal A, Singh S, Sharma N, Zengin G, Bungau S, Toma MM, Gitea D, Babes EE, Judea Pusta CT, Bumbu AG. Current Perspective on the Natural Compounds and Drug Delivery Techniques in Glioblastoma Multiforme. Cancers (Basel) 2021;13:2765. [PMID: 34199460 DOI: 10.3390/cancers13112765] [Cited by in F6Publishing: 5] [Reference Citation Analysis]
6 Molnár T, Pallagi P, Tél B, Király R, Csoma E, Jenei V, Varga Z, Gogolák P, Odile Hueber A, Máté Z, Erdélyi F, Szabó G, Pettkó-Szandtner A, Bácsi A, Virág L, Maléth J, Koncz G. Caspase-9 acts as a regulator of necroptotic cell death. FEBS J 2021. [PMID: 33899329 DOI: 10.1111/febs.15898] [Cited by in Crossref: 1] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
7 Karwi QG, Ho KL, Pherwani S, Ketema EB, Sun QY, Lopaschuk GD. Concurrent diabetes and heart failure: interplay and novel therapeutic approaches. Cardiovasc Res 2021:cvab120. [PMID: 33783483 DOI: 10.1093/cvr/cvab120] [Cited by in F6Publishing: 3] [Reference Citation Analysis]
8 Thiemicke A, Neuert G. Kinetics of osmotic stress regulate a cell fate switch of cell survival. Sci Adv 2021;7:eabe1122. [PMID: 33608274 DOI: 10.1126/sciadv.abe1122] [Cited by in Crossref: 3] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
9 Makoni NJ, Nichols MR. The intricate biophysical puzzle of caspase-1 activation. Arch Biochem Biophys 2021;699:108753. [PMID: 33453207 DOI: 10.1016/j.abb.2021.108753] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
10 Noori AR, Tashakor A, Nikkhah M, Eriksson LA, Hosseinkhani S, Fearnhead HO. Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9. Biochimie 2021;180:23-9. [PMID: 33132160 DOI: 10.1016/j.biochi.2020.10.013] [Cited by in Crossref: 2] [Cited by in F6Publishing: 8] [Article Influence: 1.0] [Reference Citation Analysis]
11 Savikj M, Kostovski E, Lundell LS, Iversen PO, Massart J, Widegren U. Altered oxidative stress and antioxidant defence in skeletal muscle during the first year following spinal cord injury. Physiol Rep 2019;7:e14218. [PMID: 31456346 DOI: 10.14814/phy2.14218] [Cited by in Crossref: 6] [Cited by in F6Publishing: 8] [Article Influence: 3.0] [Reference Citation Analysis]
12 Vigneswara V, Ahmed Z. The Role of Caspase-2 in Regulating Cell Fate. Cells 2020;9:E1259. [PMID: 32438737 DOI: 10.3390/cells9051259] [Cited by in Crossref: 11] [Cited by in F6Publishing: 20] [Article Influence: 5.5] [Reference Citation Analysis]
13 Fullstone G, Bauer TL, Guttà C, Salvucci M, Prehn JHM, Rehm M. The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer. Cell Death Differ 2020;27:2828-42. [PMID: 32341447 DOI: 10.1038/s41418-020-0545-9] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
14 Boon L, Ugarte-Berzal E, Vandooren J, Opdenakker G. Protease propeptide structures, mechanisms of activation, and functions. Crit Rev Biochem Mol Biol 2020;55:111-65. [PMID: 32290726 DOI: 10.1080/10409238.2020.1742090] [Cited by in Crossref: 9] [Cited by in F6Publishing: 15] [Article Influence: 4.5] [Reference Citation Analysis]
15 Boice A, Bouchier-Hayes L. Targeting apoptotic caspases in cancer. Biochim Biophys Acta Mol Cell Res 2020;1867:118688. [PMID: 32087180 DOI: 10.1016/j.bbamcr.2020.118688] [Cited by in Crossref: 34] [Cited by in F6Publishing: 71] [Article Influence: 17.0] [Reference Citation Analysis]
16 Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, Castoria G, Migliaccio A. ROS in cancer therapy: the bright side of the moon. Exp Mol Med 2020;52:192-203. [PMID: 32060354 DOI: 10.1038/s12276-020-0384-2] [Cited by in Crossref: 219] [Cited by in F6Publishing: 471] [Article Influence: 109.5] [Reference Citation Analysis]
17 Liu X, Song X, Luan D, Hu B, Xu K, Tang B. Real-Time in Situ Visualizing of the Sequential Activation of Caspase Cascade Using a Multicolor Gold-Selenium Bonding Fluorescent Nanoprobe. Anal Chem 2019;91:5994-6002. [PMID: 30942074 DOI: 10.1021/acs.analchem.9b00452] [Cited by in Crossref: 24] [Cited by in F6Publishing: 26] [Article Influence: 8.0] [Reference Citation Analysis]
18 Jacobs CL, Badiee RK, Lin MZ. StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins. Nat Methods 2018;15:523-6. [PMID: 29967496 DOI: 10.1038/s41592-018-0041-z] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 4.8] [Reference Citation Analysis]
19 Huber KL, Serrano BP, Hardy JA. Caspase-9 CARD : core domain interactions require a properly formed active site. Biochem J 2018;475:1177-96. [PMID: 29500231 DOI: 10.1042/BCJ20170913] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 3.3] [Reference Citation Analysis]
20 Charendoff CI, Bouchier-Hayes L. Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation. J Vis Exp 2018. [PMID: 29553529 DOI: 10.3791/57316] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
21 Noori AR, Hosseini ES, Nikkhah M, Hosseinkhani S. Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems. Arch Biochem Biophys 2018;642:46-51. [PMID: 29410086 DOI: 10.1016/j.abb.2018.01.017] [Cited by in Crossref: 8] [Cited by in F6Publishing: 13] [Article Influence: 2.0] [Reference Citation Analysis]
22 Serrano BP, Hardy JA. Phosphorylation by protein kinase A disassembles the caspase-9 core. Cell Death Differ 2018;25:1025-39. [PMID: 29352269 DOI: 10.1038/s41418-017-0052-9] [Cited by in Crossref: 21] [Cited by in F6Publishing: 20] [Article Influence: 5.3] [Reference Citation Analysis]
23 Serrano BP, Szydlo HS, Alfandari D, Hardy JA. Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9. J Biol Chem 2017;292:21352-65. [PMID: 29066624 DOI: 10.1074/jbc.M117.811976] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.2] [Reference Citation Analysis]
24 Li P, Zhou L, Zhao T, Liu X, Zhang P, Liu Y, Zheng X, Li Q. Caspase-9: structure, mechanisms and clinical application. Oncotarget 2017;8:23996-4008. [PMID: 28177918 DOI: 10.18632/oncotarget.15098] [Cited by in Crossref: 79] [Cited by in F6Publishing: 101] [Article Influence: 15.8] [Reference Citation Analysis]
25 He Y, Wang Y, Yang F, Jiang H. Manduca sexta hemolymph protease-1, activated by an unconventional non-proteolytic mechanism, mediates immune responses. Insect Biochem Mol Biol 2017;84:23-31. [PMID: 28366787 DOI: 10.1016/j.ibmb.2017.03.008] [Cited by in Crossref: 10] [Cited by in F6Publishing: 14] [Article Influence: 2.0] [Reference Citation Analysis]
26 Smith CE, Soti S, Jones TA, Nakagawa A, Xue D, Yin H. Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors. Cell Chem Biol 2017;24:281-92. [PMID: 28238723 DOI: 10.1016/j.chembiol.2017.02.003] [Cited by in Crossref: 36] [Cited by in F6Publishing: 37] [Article Influence: 7.2] [Reference Citation Analysis]
27 Li Y, Zhou M, Hu Q, Bai XC, Huang W, Scheres SH, Shi Y. Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme. Proc Natl Acad Sci U S A 2017;114:1542-7. [PMID: 28143931 DOI: 10.1073/pnas.1620626114] [Cited by in Crossref: 59] [Cited by in F6Publishing: 63] [Article Influence: 11.8] [Reference Citation Analysis]
28 Wu CC, Bratton SB. Caspase-9 swings both ways in the apoptosome. Mol Cell Oncol 2017;4:e1281865. [PMID: 28401186 DOI: 10.1080/23723556.2017.1281865] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 1.4] [Reference Citation Analysis]
29 Wu CC, Lee S, Malladi S, Chen MD, Mastrandrea NJ, Zhang Z, Bratton SB. The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities. Nat Commun 2016;7:13565. [PMID: 27882936 DOI: 10.1038/ncomms13565] [Cited by in Crossref: 41] [Cited by in F6Publishing: 41] [Article Influence: 6.8] [Reference Citation Analysis]
30 Hu J, Li F, Xu K, Ni M, Wang B, Tian J, Li Y, Shen W, Li B. Mechanisms of TiO 2 NPs-induced phoxim metabolism in silkworm ( Bombyx mori ) fat body. Pesticide Biochemistry and Physiology 2016;129:89-94. [DOI: 10.1016/j.pestbp.2015.11.004] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 3.0] [Reference Citation Analysis]
31 Xu H, Shen F, Lv Q. Celecoxib enhanced the cytotoxic effect of cisplatin in drug-resistant human gastric cancer cells by inhibition of cyclooxygenase-2. European Journal of Pharmacology 2015;769:1-7. [DOI: 10.1016/j.ejphar.2015.09.025] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 0.7] [Reference Citation Analysis]
32 Green DR, Llambi F. Cell Death Signaling. Cold Spring Harb Perspect Biol 2015;7:a006080. [PMID: 26626938 DOI: 10.1101/cshperspect.a006080] [Cited by in Crossref: 460] [Cited by in F6Publishing: 514] [Article Influence: 65.7] [Reference Citation Analysis]
33 Kang N, Cao SJ, Zhou Y, He H, Tashiro S, Onodera S, Qiu F, Ikejima T. Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells. Int J Oncol 2015;47:2045-56. [PMID: 26648189 DOI: 10.3892/ijo.2015.3186] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 3.4] [Reference Citation Analysis]
34 Zhang B, Xu Z, Zhang Y, Shao X, Xu X, Cheng J, Li Z. Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells. Pestic Biochem Physiol 2015;119:81-9. [PMID: 25868821 DOI: 10.1016/j.pestbp.2015.01.019] [Cited by in Crossref: 34] [Cited by in F6Publishing: 33] [Article Influence: 4.9] [Reference Citation Analysis]
35 Ehrenschwender M, Bittner S, Seibold K, Wajant H. XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis. Cell Death Dis 2014;5:e1570. [PMID: 25501831 DOI: 10.1038/cddis.2014.534] [Cited by in Crossref: 16] [Cited by in F6Publishing: 18] [Article Influence: 2.0] [Reference Citation Analysis]
36 Hu Q, Wu D, Chen W, Yan Z, Yan C, He T, Liang Q, Shi Y. Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome. Proc Natl Acad Sci U S A. 2014;111:16254-16261. [PMID: 25313070 DOI: 10.1073/pnas.1418000111] [Cited by in Crossref: 61] [Cited by in F6Publishing: 60] [Article Influence: 7.6] [Reference Citation Analysis]
37 Würstle ML, Rehm M. A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation. J Biol Chem 2014;289:26277-89. [PMID: 25107908 DOI: 10.1074/jbc.M114.590034] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 2.5] [Reference Citation Analysis]
38 Kobayashi Y, Shiga T, Shibata T, Sako M, Maenaka K, Koshiba T, Mizumura H, Oda T, Kawabata S. The N-terminal Arg residue is essential for autocatalytic activation of a lipopolysaccharide-responsive protease zymogen. J Biol Chem 2014;289:25987-95. [PMID: 25077965 DOI: 10.1074/jbc.M114.586933] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.5] [Reference Citation Analysis]
39 Xie Y, Wang B, Li F, Ma L, Ni M, Shen W, Hong F, Li B. Molecular mechanisms of reduced nerve toxicity by titanium dioxide nanoparticles in the phoxim-exposed brain of Bombyx mori. PLoS One 2014;9:e101062. [PMID: 24971466 DOI: 10.1371/journal.pone.0101062] [Cited by in Crossref: 19] [Cited by in F6Publishing: 20] [Article Influence: 2.4] [Reference Citation Analysis]
40 Zhao Y, Lei M, Wang Z, Qiao G, Yang T, Zhang J. TCR-induced, PKC-θ-mediated NF-κB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade. Biochem Biophys Res Commun 2014;450:526-31. [PMID: 24924627 DOI: 10.1016/j.bbrc.2014.06.010] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 2.0] [Reference Citation Analysis]
41 Zeng W, Zhang J, Qi M, Peng C, Su J, Chen X, Yuan Z. αNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells. Cell Death Dis 2014;5:e1282. [PMID: 24901053 DOI: 10.1038/cddis.2014.192] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
42 Kim CH, Paik D, Rus F, Silverman N. The caspase-8 homolog Dredd cleaves Imd and Relish but is not inhibited by p35. J Biol Chem 2014;289:20092-101. [PMID: 24891502 DOI: 10.1074/jbc.M113.544841] [Cited by in Crossref: 28] [Cited by in F6Publishing: 26] [Article Influence: 3.5] [Reference Citation Analysis]
43 Poreba M, Kasperkiewicz P, Snipas SJ, Fasci D, Salvesen GS, Drag M. Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates. Cell Death Differ 2014;21:1482-92. [PMID: 24832467 DOI: 10.1038/cdd.2014.64] [Cited by in Crossref: 64] [Cited by in F6Publishing: 56] [Article Influence: 8.0] [Reference Citation Analysis]
44 Huber HJ, McKiernan RG, Prehn JH. Harnessing system models of cell death signalling for cytotoxic chemotherapy: towards personalised medicine approaches? J Mol Med (Berl) 2014;92:227-37. [PMID: 24477766 DOI: 10.1007/s00109-014-1126-5] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 1.0] [Reference Citation Analysis]
45 Chai J, Shi Y. Apoptosome and inflammasome: conserved machineries for caspase activation. National Science Review 2014;1:101-18. [DOI: 10.1093/nsr/nwt025] [Cited by in Crossref: 26] [Cited by in F6Publishing: 17] [Article Influence: 3.3] [Reference Citation Analysis]
46 Ma C, Cheng S, Hu Z, Li Q, Zhang R, Zhang S. Synthesis and characterization of a novel o-tolyltelluronic trimethyltin ester and its cytotoxic assessment in vitro. Dalton Trans 2014;43:671-9. [DOI: 10.1039/c3dt52326h] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 1.1] [Reference Citation Analysis]
47 Chandna S, Suman S, Chandna M, Pandey A, Singh V, Kumar A, Dwarakanath BS, Seth RK. Radioresistant Sf9 insect cells undergo an atypical form of Bax-dependent apoptosis at very high doses of γ-radiation. Int J Radiat Biol 2013;89:1017-27. [PMID: 23859363 DOI: 10.3109/09553002.2013.825059] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 1.2] [Reference Citation Analysis]
48 Raychaudhuri S, Raychaudhuri SC. Monte carlo study elucidates the type 1/type 2 choice in apoptotic death signaling in healthy and cancer cells. Cells 2013;2:361-92. [PMID: 24709706 DOI: 10.3390/cells2020361] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
49 Simon DJ, Weimer RM, McLaughlin T, Kallop D, Stanger K, Yang J, O'Leary DD, Hannoush RN, Tessier-Lavigne M. A caspase cascade regulating developmental axon degeneration. J Neurosci 2012;32:17540-53. [PMID: 23223278 DOI: 10.1523/JNEUROSCI.3012-12.2012] [Cited by in Crossref: 134] [Cited by in F6Publishing: 142] [Article Influence: 14.9] [Reference Citation Analysis]
50 Hu Q, Wu D, Chen W, Yan Z, Shi Y. Proteolytic processing of the caspase-9 zymogen is required for apoptosome-mediated activation of caspase-9. J Biol Chem 2013;288:15142-7. [PMID: 23572523 DOI: 10.1074/jbc.M112.441568] [Cited by in Crossref: 36] [Cited by in F6Publishing: 38] [Article Influence: 4.0] [Reference Citation Analysis]
51 Huang J, Lv C, Hu M, Zhong G. The mitochondria-mediate apoptosis of Lepidopteran cells induced by azadirachtin. PLoS One 2013;8:e58499. [PMID: 23516491 DOI: 10.1371/journal.pone.0058499] [Cited by in Crossref: 34] [Cited by in F6Publishing: 40] [Article Influence: 3.8] [Reference Citation Analysis]
52 de Pedro N, Cautain B, Melguizo A, Vicente F, Genilloud O, Peláez F, Tormo JR. Mitochondrial complex I inhibitors, acetogenins, induce HepG2 cell death through the induction of the complete apoptotic mitochondrial pathway. J Bioenerg Biomembr 2013;45:153-64. [PMID: 23180140 DOI: 10.1007/s10863-012-9489-1] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 2.3] [Reference Citation Analysis]
53 Wu CC, Bratton SB. Regulation of the intrinsic apoptosis pathway by reactive oxygen species. Antioxid Redox Signal 2013;19:546-58. [PMID: 22978471 DOI: 10.1089/ars.2012.4905] [Cited by in Crossref: 228] [Cited by in F6Publishing: 222] [Article Influence: 22.8] [Reference Citation Analysis]
54 Carvalho Rodrigues MA, Gobe G, Santos NAG, Santos AC. Carvedilol Protects Against Apoptotic Cell Death Induced by Cisplatin in Renal Tubular Epithelial Cells. Journal of Toxicology and Environmental Health, Part A 2012;75:981-90. [DOI: 10.1080/15287394.2012.696512] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 1.4] [Reference Citation Analysis]
55 Rodríguez-enfedaque A, Delmas E, Guillaume A, Gaumer S, Mignotte B, Vayssière J, Renaud F. zVAD-fmk upregulates caspase-9 cleavage and activity in etoposide-induced cell death of mouse embryonic fibroblasts. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2012;1823:1343-52. [DOI: 10.1016/j.bbamcr.2012.05.013] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 1.1] [Reference Citation Analysis]
56 Ribe EM, Jean YY, Goldstein RL, Manzl C, Stefanis L, Villunger A, Troy CM. Neuronal caspase 2 activity and function requires RAIDD, but not PIDD. Biochem J 2012;444:591-9. [PMID: 22515271 DOI: 10.1042/BJ20111588] [Cited by in Crossref: 31] [Cited by in F6Publishing: 29] [Article Influence: 3.1] [Reference Citation Analysis]
57 Edgington LE, van Raam BJ, Verdoes M, Wierschem C, Salvesen GS, Bogyo M. An optimized activity-based probe for the study of caspase-6 activation. Chem Biol 2012;19:340-52. [PMID: 22444589 DOI: 10.1016/j.chembiol.2011.12.021] [Cited by in Crossref: 42] [Cited by in F6Publishing: 42] [Article Influence: 4.2] [Reference Citation Analysis]
58 Parcq J, Bertrand T, Montagne A, Baron AF, Macrez R, Billard JM, Briens A, Hommet Y, Wu J, Yepes M, Lijnen HR, Dutar P, Anglés-Cano E, Vivien D. Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity. Cell Death Differ 2012;19:1983-91. [PMID: 22743997 DOI: 10.1038/cdd.2012.86] [Cited by in Crossref: 39] [Cited by in F6Publishing: 44] [Article Influence: 3.9] [Reference Citation Analysis]
59 Akhter A, Caution K, Abu Khweek A, Tazi M, Abdulrahman BA, Abdelaziz DH, Voss OH, Doseff AI, Hassan H, Azad AK, Schlesinger LS, Wewers MD, Gavrilin MA, Amer AO. Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. Immunity 2012;37:35-47. [PMID: 22658523 DOI: 10.1016/j.immuni.2012.05.001] [Cited by in Crossref: 129] [Cited by in F6Publishing: 129] [Article Influence: 12.9] [Reference Citation Analysis]
60 Huber KL, Hardy JA. Mechanism of zinc-mediated inhibition of caspase-9. Protein Sci 2012;21:1056-65. [PMID: 22573662 DOI: 10.1002/pro.2090] [Cited by in Crossref: 53] [Cited by in F6Publishing: 52] [Article Influence: 5.3] [Reference Citation Analysis]
61 Conus S, Pop C, Snipas SJ, Salvesen GS, Simon HU. Cathepsin D primes caspase-8 activation by multiple intra-chain proteolysis. J Biol Chem 2012;287:21142-51. [PMID: 22528489 DOI: 10.1074/jbc.M111.306399] [Cited by in Crossref: 34] [Cited by in F6Publishing: 38] [Article Influence: 3.4] [Reference Citation Analysis]
62 Reubold TF, Eschenburg S. A molecular view on signal transduction by the apoptosome. Cell Signal. 2012;24:1420-1425. [PMID: 22446004 DOI: 10.1016/j.cellsig.2012.03.007] [Cited by in Crossref: 95] [Cited by in F6Publishing: 100] [Article Influence: 9.5] [Reference Citation Analysis]
63 Würstle ML, Laussmann MA, Rehm M. The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp Cell Res. 2012;318:1213-1220. [PMID: 22406265 DOI: 10.1016/j.yexcr.2012.02.013] [Cited by in Crossref: 155] [Cited by in F6Publishing: 157] [Article Influence: 15.5] [Reference Citation Analysis]
64 Zhang X, Tao K, Hou T. Investigation of 1-(4-morpholinophenyl)-3-(4-fluorophenyl)-propenone and 1-(4-morpholinophenyl)-3-(3-fluorophenyl)-propenone as new apoptosis inducers on Spodoptera frugiperda (Sf9) cells. Toxicol Mech Methods 2012;22:315-20. [PMID: 22339240 DOI: 10.3109/15376516.2012.658979] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
65 Szegezdi E, van der Sloot AM, Mahalingam D, O'Leary L, Cool RH, Muñoz IG, Montoya G, Quax WJ, de Jong S, Samali A, Serrano L. Kinetics in signal transduction pathways involving promiscuous oligomerizing receptors can be determined by receptor specificity: apoptosis induction by TRAIL. Mol Cell Proteomics 2012;11:M111.013730. [PMID: 22213832 DOI: 10.1074/mcp.M111.013730] [Cited by in Crossref: 21] [Cited by in F6Publishing: 21] [Article Influence: 2.1] [Reference Citation Analysis]
66 Broz P, Monack DM. Molecular mechanisms of inflammasome activation during microbial infections. Immunol Rev. 2011;243:174-190. [PMID: 21884176 DOI: 10.1111/j.1600-065x.2011.01041.x] [Cited by in Crossref: 175] [Cited by in F6Publishing: 174] [Article Influence: 15.9] [Reference Citation Analysis]
67 Reubold T, Wohlgemuth S, Eschenburg S. Crystal Structure of Full-Length Apaf-1: How the Death Signal Is Relayed in the Mitochondrial Pathway of Apoptosis. Structure 2011;19:1074-83. [DOI: 10.1016/j.str.2011.05.013] [Cited by in Crossref: 80] [Cited by in F6Publishing: 82] [Article Influence: 7.3] [Reference Citation Analysis]
68 Boucher D, Blais V, Drag M, Denault JB. Molecular determinants involved in activation of caspase 7. Biosci Rep 2011;31:283-94. [PMID: 20942802 DOI: 10.1042/BSR20100111] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 1.4] [Reference Citation Analysis]
69 Huang J, Tian M, Lv C, Li H, Muhammad R, Zhong G. Preliminary studies on induction of apoptosis by abamectin in Spodoptera frugiperda (Sf9) cell line. Pesticide Biochemistry and Physiology 2011;100:256-63. [DOI: 10.1016/j.pestbp.2011.04.010] [Cited by in Crossref: 36] [Cited by in F6Publishing: 25] [Article Influence: 3.3] [Reference Citation Analysis]
70 Northington FJ, Chavez-Valdez R, Martin LJ. Neuronal cell death in neonatal hypoxia-ischemia. Ann Neurol 2011;69:743-58. [PMID: 21520238 DOI: 10.1002/ana.22419] [Cited by in Crossref: 237] [Cited by in F6Publishing: 224] [Article Influence: 21.5] [Reference Citation Analysis]
71 Manns J, Daubrawa M, Driessen S, Paasch F, Hoffmann N, Löffler A, Lauber K, Dieterle A, Alers S, Iftner T, Schulze-Osthoff K, Stork B, Wesselborg S. Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1. FASEB J 2011;25:3250-61. [PMID: 21659556 DOI: 10.1096/fj.10-177527] [Cited by in Crossref: 60] [Cited by in F6Publishing: 62] [Article Influence: 5.5] [Reference Citation Analysis]
72 Filhol O, Cochet C. Protein Kinases Curb Cell Death. Sci Signal 2011;4. [DOI: 10.1126/scisignal.2001921] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
73 Bratton SB, Salvesen GS. Regulation of the Apaf-1-caspase-9 apoptosome. J Cell Sci. 2010;123:3209-3214. [PMID: 20844150 DOI: 10.1242/jcs.073643] [Cited by in Crossref: 228] [Cited by in F6Publishing: 241] [Article Influence: 20.7] [Reference Citation Analysis]
74 Broz P, von Moltke J, Jones JW, Vance RE, Monack DM. Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe 2010;8:471-83. [PMID: 21147462 DOI: 10.1016/j.chom.2010.11.007] [Cited by in Crossref: 362] [Cited by in F6Publishing: 370] [Article Influence: 32.9] [Reference Citation Analysis]
75 Vaidya S, Velázquez-Delgado EM, Abbruzzese G, Hardy JA. Substrate-induced conformational changes occur in all cleaved forms of caspase-6. J Mol Biol 2011;406:75-91. [PMID: 21111746 DOI: 10.1016/j.jmb.2010.11.031] [Cited by in Crossref: 45] [Cited by in F6Publishing: 41] [Article Influence: 3.8] [Reference Citation Analysis]
76 Janson V, Johansson A, Grankvist K. Resistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance. Cell Death Dis 2010;1:e78. [PMID: 21364680 DOI: 10.1038/cddis.2010.54] [Cited by in Crossref: 16] [Cited by in F6Publishing: 20] [Article Influence: 1.3] [Reference Citation Analysis]
77 Lee HJ, Lee SH, Park SH, Sharoar MG, Shin SY, Lee JS, Cho B, Park IS. Purification of catalytically active caspase-12 and its biochemical characterization. Arch Biochem Biophys. 2010;502:68-73. [PMID: 20646990 DOI: 10.1016/j.abb.2010.07.013] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
78 Ripple MO, Abajian M, Springett R. Cytochrome c is rapidly reduced in the cytosol after mitochondrial outer membrane permeabilization. Apoptosis 2010;15:563-73. [PMID: 20094799 DOI: 10.1007/s10495-010-0455-2] [Cited by in Crossref: 34] [Cited by in F6Publishing: 36] [Article Influence: 2.8] [Reference Citation Analysis]
79 Shemarova IV. Signaling mechanisms of apoptosis-like programmed cell death in unicellular eukaryotes. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 2010;155:341-53. [DOI: 10.1016/j.cbpb.2010.01.010] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 1.8] [Reference Citation Analysis]
80 Oberst A, Pop C, Tremblay AG, Blais V, Denault JB, Salvesen GS, Green DR. Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation. J Biol Chem 2010;285:16632-42. [PMID: 20308068 DOI: 10.1074/jbc.M109.095083] [Cited by in Crossref: 133] [Cited by in F6Publishing: 124] [Article Influence: 11.1] [Reference Citation Analysis]
81 Pratt MR, Sekedat MD, Chiang KP, Muir TW. Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe. Chem Biol 2009;16:1001-12. [PMID: 19778728 DOI: 10.1016/j.chembiol.2009.07.011] [Cited by in Crossref: 29] [Cited by in F6Publishing: 30] [Article Influence: 2.4] [Reference Citation Analysis]
82 Ummanni R, Lehnigk U, Zimmermann U, Woenckhaus C, Walther R, Giebel J. Immunohistochemical expression of caspase-1 and -9, uncleaved caspase-3 and -6, cleaved caspase-3 and -6 as well as Bcl-2 in benign epithelium and cancer of the prostate. Exp Ther Med 2010;1:47-52. [PMID: 23136591 DOI: 10.3892/etm_00000008] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 1.1] [Reference Citation Analysis]
83 Zhai D, Yu E, Jin C, Welsh K, Shiau CW, Chen L, Salvesen GS, Liddington R, Reed JC. Vaccinia virus protein F1L is a caspase-9 inhibitor. J Biol Chem 2010;285:5569-80. [PMID: 20022954 DOI: 10.1074/jbc.M109.078113] [Cited by in Crossref: 31] [Cited by in F6Publishing: 31] [Article Influence: 2.4] [Reference Citation Analysis]
84 Reubold TF, Wohlgemuth S, Eschenburg S. A new model for the transition of APAF-1 from inactive monomer to caspase-activating apoptosome. J Biol Chem 2009;284:32717-24. [PMID: 19801675 DOI: 10.1074/jbc.M109.014027] [Cited by in Crossref: 46] [Cited by in F6Publishing: 46] [Article Influence: 3.5] [Reference Citation Analysis]
85 Kitevska T, Spencer DM, Hawkins CJ. Caspase-2: controversial killer or checkpoint controller? Apoptosis 2009;14:829-48. [PMID: 19479377 DOI: 10.1007/s10495-009-0365-3] [Cited by in Crossref: 33] [Cited by in F6Publishing: 31] [Article Influence: 2.5] [Reference Citation Analysis]
86 Chen L, Hu L, Chan TH, Tsao GS, Xie D, Huo KK, Fu L, Ma S, Zheng BJ, Guan XY. Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival. Hepatology. 2009;50:122-129. [PMID: 19441106 DOI: org/10.1002/hep.22933] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
87 Beck M, Karch C, Wiese S, Sendtner M. Motoneuron cell death and neurotrophic factors: Basic models for development of new therapeutic strategies in ALS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 2009;2:s55-68. [DOI: 10.1080/146608201300079454] [Cited by in Crossref: 14] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
88 Chen L, Hu L, Chan TH, Tsao GS, Xie D, Huo KK, Fu L, Ma S, Zheng BJ, Guan XY. Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival. Hepatology 2009;50:122-9. [PMID: 19441106 DOI: 10.1002/hep.22933] [Cited by in Crossref: 49] [Cited by in F6Publishing: 54] [Article Influence: 3.8] [Reference Citation Analysis]
89 Malladi S, Challa-Malladi M, Fearnhead HO, Bratton SB. The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer. EMBO J 2009;28:1916-25. [PMID: 19494828 DOI: 10.1038/emboj.2009.152] [Cited by in Crossref: 81] [Cited by in F6Publishing: 82] [Article Influence: 6.2] [Reference Citation Analysis]
90 Orme M, Meier P. Inhibitor of apoptosis proteins in Drosophila: gatekeepers of death. Apoptosis 2009;14:950-60. [PMID: 19495985 DOI: 10.1007/s10495-009-0358-2] [Cited by in Crossref: 82] [Cited by in F6Publishing: 74] [Article Influence: 6.3] [Reference Citation Analysis]
91 Keller N, Mares J, Zerbe O, Grütter MG. Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation. Structure 2009;17:438-48. [PMID: 19278658 DOI: 10.1016/j.str.2008.12.019] [Cited by in Crossref: 63] [Cited by in F6Publishing: 57] [Article Influence: 4.8] [Reference Citation Analysis]
92 Ryu S, Lin SC, Ugel N, Antoniotti M, Mishra B. Mathematical modeling of the formation of apoptosome in intrinsic pathway of apoptosis. Syst Synth Biol 2008;2:49-66. [PMID: 19333786 DOI: 10.1007/s11693-009-9022-y] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
93 Inoue S, Browne G, Melino G, Cohen GM. Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway. Cell Death Differ. 2009;16:1053-1061. [PMID: 19325570 DOI: 10.1038/cdd.2009.29] [Cited by in Crossref: 141] [Cited by in F6Publishing: 138] [Article Influence: 10.8] [Reference Citation Analysis]
94 Sohn D, Graupner V, Neise D, Essmann F, Schulze-osthoff K, Jänicke RU. Pifithrin-α protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53. Cell Death Differ 2009;16:869-78. [DOI: 10.1038/cdd.2009.17] [Cited by in Crossref: 71] [Cited by in F6Publishing: 69] [Article Influence: 5.5] [Reference Citation Analysis]
95 Kumarswamy R, Seth RK, Dwarakanath BS, Chandna S. Mitochondrial regulation of insect cell apoptosis: evidence for permeability transition pore-independent cytochrome-c release in the Lepidopteran Sf9 cells. Int J Biochem Cell Biol 2009;41:1430-40. [PMID: 19146980 DOI: 10.1016/j.biocel.2008.12.009] [Cited by in Crossref: 50] [Cited by in F6Publishing: 55] [Article Influence: 3.6] [Reference Citation Analysis]
96 de Bruin EC, Medema JP. Apoptosis and non-apoptotic deaths in cancer development and treatment response. Cancer Treatment Reviews 2008;34:737-49. [DOI: 10.1016/j.ctrv.2008.07.001] [Cited by in Crossref: 188] [Cited by in F6Publishing: 185] [Article Influence: 13.4] [Reference Citation Analysis]
97 Jin D, Ojcius DM, Sun D, Dong H, Luo Y, Mao Y, Yan J. Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways. Infect Immun 2009;77:799-809. [PMID: 19029301 DOI: 10.1128/IAI.00914-08] [Cited by in Crossref: 55] [Cited by in F6Publishing: 47] [Article Influence: 3.9] [Reference Citation Analysis]
98 Seifert A, Allan LA, Clarke PR. DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine. FEBS J 2008;275:6268-80. [PMID: 19016842 DOI: 10.1111/j.1742-4658.2008.06751.x] [Cited by in Crossref: 81] [Cited by in F6Publishing: 86] [Article Influence: 5.8] [Reference Citation Analysis]
99 Paschen SA, Christian JG, Vier J, Schmidt F, Walch A, Ojcius DM, Häcker G. Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease. J Cell Biol 2008;182:117-27. [PMID: 18625845 DOI: 10.1083/jcb.200804023] [Cited by in Crossref: 44] [Cited by in F6Publishing: 43] [Article Influence: 3.1] [Reference Citation Analysis]
100 Yu X, Acehan D, Ménétret JF, Booth CR, Ludtke SJ, Riedl SJ, Shi Y, Wang X, Akey CW. A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. Structure 2005;13:1725-35. [PMID: 16271896 DOI: 10.1016/j.str.2005.09.006] [Cited by in Crossref: 115] [Cited by in F6Publishing: 101] [Article Influence: 8.2] [Reference Citation Analysis]
101 Kurokawa M, Zhao C, Reya T, Kornbluth S. Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias. Mol Cell Biol 2008;28:5494-506. [PMID: 18591256 DOI: 10.1128/MCB.00265-08] [Cited by in Crossref: 58] [Cited by in F6Publishing: 55] [Article Influence: 4.1] [Reference Citation Analysis]
102 Simpson CD, Anyiwe K, Schimmer AD. Anoikis resistance and tumor metastasis. Cancer Lett. 2008;272:177-185. [PMID: 18579285 DOI: 10.1016/j.canlet.2008.05.029] [Cited by in Crossref: 321] [Cited by in F6Publishing: 335] [Article Influence: 22.9] [Reference Citation Analysis]
103 Salvesen GS, Riedl SJ. Caspase mechanisms. Adv Exp Med Biol 2008;615:13-23. [PMID: 18437889 DOI: 10.1007/978-1-4020-6554-5_2] [Cited by in Crossref: 145] [Cited by in F6Publishing: 147] [Article Influence: 10.4] [Reference Citation Analysis]
104 McDonnell MA, Abedin MJ, Melendez M, Platikanova TN, Ecklund JR, Ahmed K, Kelekar A. Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8. J Biol Chem 2008;283:20149-58. [PMID: 18467326 DOI: 10.1074/jbc.M802846200] [Cited by in Crossref: 36] [Cited by in F6Publishing: 33] [Article Influence: 2.6] [Reference Citation Analysis]
105 Kaufmann SH, Lee SH, Meng XW, Loegering DA, Kottke TJ, Henzing AJ, Ruchaud S, Samejima K, Earnshaw WC. Apoptosis-associated caspase activation assays. Methods 2008;44:262-72. [PMID: 18314058 DOI: 10.1016/j.ymeth.2007.11.005] [Cited by in Crossref: 56] [Cited by in F6Publishing: 50] [Article Influence: 4.0] [Reference Citation Analysis]
106 MacKenzie SH, Clark AC. Targeting cell death in tumors by activating caspases. Curr Cancer Drug Targets 2008;8:98-109. [PMID: 18336192 DOI: 10.2174/156800908783769391] [Cited by in Crossref: 59] [Cited by in F6Publishing: 58] [Article Influence: 4.2] [Reference Citation Analysis]
107 Snipas SJ, Drag M, Stennicke HR, Salvesen GS. Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC. Cell Death Differ 2008;15:938-45. [PMID: 18309328 DOI: 10.1038/cdd.2008.23] [Cited by in Crossref: 33] [Cited by in F6Publishing: 30] [Article Influence: 2.4] [Reference Citation Analysis]
108 Son KN, Becker RP, Kallio P, Lipton HL. Theiler's virus-induced intrinsic apoptosis in M1-D macrophages is Bax mediated and restricts virus infectivity: a mechanism for persistence of a cytolytic virus. J Virol 2008;82:4502-10. [PMID: 18287228 DOI: 10.1128/JVI.02349-07] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 1.6] [Reference Citation Analysis]
109 Dorstyn L, Kumar S. A biochemical analysis of the activation of the Drosophila caspase DRONC. Cell Death Differ 2008;15:461-70. [DOI: 10.1038/sj.cdd.4402288] [Cited by in Crossref: 42] [Cited by in F6Publishing: 36] [Article Influence: 2.8] [Reference Citation Analysis]
110 Lang-Rollin I, Maniati M, Jabado O, Vekrellis K, Papantonis S, Rideout HJ, Stefanis L. Apoptosis and the conformational change of Bax induced by proteasomal inhibition of PC12 cells are inhibited by bcl-xL and bcl-2. Apoptosis 2005;10:809-20. [PMID: 16133871 DOI: 10.1007/s10495-005-0378-5] [Cited by in Crossref: 27] [Cited by in F6Publishing: 22] [Article Influence: 1.8] [Reference Citation Analysis]
111 Ozben T. Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci 2007;96:2181-96. [PMID: 17593552 DOI: 10.1002/jps.20874] [Cited by in Crossref: 450] [Cited by in F6Publishing: 454] [Article Influence: 30.0] [Reference Citation Analysis]
112 McStay GP, Salvesen GS, Green DR. Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways. Cell Death Differ 2008;15:322-31. [PMID: 17975551 DOI: 10.1038/sj.cdd.4402260] [Cited by in Crossref: 232] [Cited by in F6Publishing: 209] [Article Influence: 15.5] [Reference Citation Analysis]
113 Hunter AM, LaCasse EC, Korneluk RG. The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis. 2007;12:1543-1568. [PMID: 17573556 DOI: 10.1007/s10495-007-0087-3] [Cited by in Crossref: 379] [Cited by in F6Publishing: 357] [Article Influence: 25.3] [Reference Citation Analysis]
114 Twiddy D, Cain K. Caspase-9 cleavage, do you need it? Biochem J 2007;405:e1-2. [PMID: 17555401 DOI: 10.1042/BJ20070617] [Cited by in Crossref: 38] [Cited by in F6Publishing: 37] [Article Influence: 2.5] [Reference Citation Analysis]
115 Franklin EE, Robertson JD. Requirement of Apaf-1 for mitochondrial events and the cleavage or activation of all procaspases during genotoxic stress-induced apoptosis. Biochem J 2007;405:115-22. [PMID: 17348858 DOI: 10.1042/BJ20061576] [Cited by in Crossref: 25] [Cited by in F6Publishing: 21] [Article Influence: 1.7] [Reference Citation Analysis]
116 Denault JB, Eckelman BP, Shin H, Pop C, Salvesen GS. Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9. Biochem J 2007;405:11-9. [PMID: 17437405 DOI: 10.1042/BJ20070288] [Cited by in Crossref: 70] [Cited by in F6Publishing: 61] [Article Influence: 4.7] [Reference Citation Analysis]
117 Gao MQ, Guo SB, Chen XH, Du W, Wang CB. Molecular mechanisms of polypeptide from Chlamys farreri protecting HaCaT cells from apoptosis induced by UVA plus UVB. Acta Pharmacol Sin 2007;28:1007-14. [PMID: 17588337 DOI: 10.1111/j.1745-7254.2007.00594.x] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 0.7] [Reference Citation Analysis]
118 Sharma R, Gow A. Minimal role for caspase 12 in the unfolded protein response in oligodendrocytes in vivo. J Neurochem 2007;101:889-97. [PMID: 17394578 DOI: 10.1111/j.1471-4159.2007.04541.x] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 1.0] [Reference Citation Analysis]
119 Serradell MC, Guasconi L, Cervi L, Chiapello LS, Masih DT. Excretory-secretory products from Fasciola hepatica induce eosinophil apoptosis by a caspase-dependent mechanism. Vet Immunol Immunopathol 2007;117:197-208. [PMID: 17449115 DOI: 10.1016/j.vetimm.2007.03.007] [Cited by in Crossref: 56] [Cited by in F6Publishing: 54] [Article Influence: 3.7] [Reference Citation Analysis]
120 Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol. 2007;8:405-413. [PMID: 17377525 DOI: 10.1038/nrm2153] [Cited by in Crossref: 689] [Cited by in F6Publishing: 671] [Article Influence: 45.9] [Reference Citation Analysis]
121 Bao Q, Lu W, Rabinowitz JD, Shi Y. Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1. Mol Cell. 2007;25:181-192. [PMID: 17244527 DOI: 10.1016/j.molcel.2006.12.013] [Cited by in Crossref: 67] [Cited by in F6Publishing: 64] [Article Influence: 4.5] [Reference Citation Analysis]
122 Ma X, Kalakonda S, Srinivasula SM, Reddy SP, Platanias LC, Kalvakolanu DV. GRIM-19 associates with the serine protease HtrA2 for promoting cell death. Oncogene 2007;26:4842-9. [DOI: 10.1038/sj.onc.1210287] [Cited by in Crossref: 30] [Cited by in F6Publishing: 29] [Article Influence: 2.0] [Reference Citation Analysis]
123 Checinska A, Hoogeland BS, Rodriguez JA, Giaccone G, Kruyt FA. Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation. Exp Cell Res. 2007;313:1215-1224. [PMID: 17291493 DOI: 10.1016/j.yexcr.2006.12.011] [Cited by in Crossref: 32] [Cited by in F6Publishing: 31] [Article Influence: 2.0] [Reference Citation Analysis]
124 Feeney B, Pop C, Swartz P, Mattos C, Clark AC. Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3. Biochemistry 2006;45:13249-63. [PMID: 17073446 DOI: 10.1021/bi0611964] [Cited by in Crossref: 50] [Cited by in F6Publishing: 49] [Article Influence: 3.1] [Reference Citation Analysis]
125 Festjens N, Cornelis S, Lamkanfi M, Vandenabeele P. Caspase-containing complexes in the regulation of cell death and inflammation. Biol Chem 2006;387:1005-16. [PMID: 16895469 DOI: 10.1515/BC.2006.124] [Cited by in Crossref: 20] [Cited by in F6Publishing: 22] [Article Influence: 1.3] [Reference Citation Analysis]
126 Timmer JC, Salvesen GS. Caspase substrates. Cell Death Differ 2007;14:66-72. [DOI: 10.1038/sj.cdd.4402059] [Cited by in Crossref: 287] [Cited by in F6Publishing: 266] [Article Influence: 17.9] [Reference Citation Analysis]
127 Eckhart L, Kittel C, Ballaun C, Tschachler E. Caspase-15 is autoprocessed at two sites that contain an aspartate residue in the P1' position. Biochem Biophys Res Commun 2006;350:955-9. [PMID: 17045244 DOI: 10.1016/j.bbrc.2006.09.130] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
128 Bao Q, Shi Y. Apoptosome: a platform for the activation of initiator caspases. Cell Death Differ 2007;14:56-65. [DOI: 10.1038/sj.cdd.4402028] [Cited by in Crossref: 264] [Cited by in F6Publishing: 246] [Article Influence: 16.5] [Reference Citation Analysis]
129 Gyrd-Hansen M, Farkas T, Fehrenbacher N, Bastholm L, Høyer-Hansen M, Elling F, Wallach D, Flavell R, Kroemer G, Nylandsted J, Jäättelä M. Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol Cell Biol 2006;26:7880-91. [PMID: 16966373 DOI: 10.1128/MCB.00716-06] [Cited by in Crossref: 81] [Cited by in F6Publishing: 77] [Article Influence: 5.1] [Reference Citation Analysis]
130 Ganesan R, Jelakovic S, Campbell AJ, Li ZZ, Asgian JL, Powers JC, Grütter MG. Exploring the S4 and S1 prime subsite specificities in caspase-3 with aza-peptide epoxide inhibitors. Biochemistry 2006;45:9059-67. [PMID: 16866351 DOI: 10.1021/bi060364p] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 1.2] [Reference Citation Analysis]
131 Berger AB, Witte MD, Denault J, Sadaghiani AM, Sexton KM, Salvesen GS, Bogyo M. Identification of Early Intermediates of Caspase Activation Using Selective Inhibitors and Activity-Based Probes. Molecular Cell 2006;23:509-21. [DOI: 10.1016/j.molcel.2006.06.021] [Cited by in Crossref: 95] [Cited by in F6Publishing: 89] [Article Influence: 5.9] [Reference Citation Analysis]
132 Pop C, Timmer J, Sperandio S, Salvesen GS. The apoptosome activates caspase-9 by dimerization. Mol Cell 2006;22:269-75. [PMID: 16630894 DOI: 10.1016/j.molcel.2006.03.009] [Cited by in Crossref: 198] [Cited by in F6Publishing: 181] [Article Influence: 12.4] [Reference Citation Analysis]
133 Yin Q, Park HH, Chung JY, Lin SC, Lo YC, da Graca LS, Jiang X, Wu H. Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine. Mol Cell 2006;22:259-68. [PMID: 16630893 DOI: 10.1016/j.molcel.2006.03.030] [Cited by in Crossref: 68] [Cited by in F6Publishing: 63] [Article Influence: 4.3] [Reference Citation Analysis]
134 Richburg JH. The Role of Death Receptor Signaling in Testicular Germ-Cell Apoptosis Triggered by Mono-(2-ethylhexyl) Phthalate (MEHP)-Induced Sertoli Cell Injury and Its Implications for Risk Assessment. Journal of Toxicology and Environmental Health, Part A 2006;69:793-809. [DOI: 10.1080/15287390600591447] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
135 Darnowski JW, Goulette FA, Guan YJ, Chatterjee D, Yang ZF, Cousens LP, Chin YE. Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. J Biol Chem 2006;281:17707-17. [PMID: 16636048 DOI: 10.1074/jbc.M600088200] [Cited by in Crossref: 38] [Cited by in F6Publishing: 38] [Article Influence: 2.4] [Reference Citation Analysis]
136 Theas M, Rival C, Dietrich S, Guazzone V, Lustig L. Death receptor and mitochondrial pathways are involved in germ cell apoptosis in an experimental model of autoimmune orchitis. Human Reproduction 2006;21:1734-42. [DOI: 10.1093/humrep/del066] [Cited by in Crossref: 27] [Cited by in F6Publishing: 20] [Article Influence: 1.7] [Reference Citation Analysis]
137 Sadhukhan R, Leone JW, Lull J, Wang Z, Kletzien RF, Heinrikson RL, Tomasselli AG. An efficient method to express and refold a truncated human procaspase-9: A caspase with activity toward Glu-X bonds. Protein Expression and Purification 2006;46:299-308. [DOI: 10.1016/j.pep.2005.09.006] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
138 Pelletier N, Casamayor-Pallejà M, De Luca K, Mondière P, Saltel F, Jurdic P, Bella C, Genestier L, Defrance T. The endoplasmic reticulum is a key component of the plasma cell death pathway. J Immunol 2006;176:1340-7. [PMID: 16424160 DOI: 10.4049/jimmunol.176.3.1340] [Cited by in Crossref: 46] [Cited by in F6Publishing: 47] [Article Influence: 2.9] [Reference Citation Analysis]
139 Daniels I, Abulayha AM, Thomson BJ, Haynes AP. Caspase-independent killing of Burkitt lymphoma cell lines by rituximab. Apoptosis 2006;11:1013-23. [DOI: 10.1007/s10495-006-6314-5] [Cited by in Crossref: 35] [Cited by in F6Publishing: 30] [Article Influence: 2.2] [Reference Citation Analysis]
140 Li W, Galey D, Mattson MP, Nath A. Molecular and cellular mechanisms of neuronal cell death in HIV dementia. Neurotox Res 2005;8:119-34. [PMID: 16260390 DOI: 10.1007/BF03033824] [Cited by in Crossref: 59] [Cited by in F6Publishing: 58] [Article Influence: 3.7] [Reference Citation Analysis]
141 Yan N, Huh JR, Schirf V, Demeler B, Hay BA, Shi Y. Structure and activation mechanism of the Drosophila initiator caspase Dronc. J Biol Chem 2006;281:8667-74. [PMID: 16446367 DOI: 10.1074/jbc.M513232200] [Cited by in Crossref: 36] [Cited by in F6Publishing: 35] [Article Influence: 2.3] [Reference Citation Analysis]
142 Yu X, Wang L, Acehan D, Wang X, Akey CW. Three-dimensional Structure of a Double Apoptosome Formed by the Drosophila Apaf-1 Related Killer. Journal of Molecular Biology 2006;355:577-89. [DOI: 10.1016/j.jmb.2005.10.040] [Cited by in Crossref: 99] [Cited by in F6Publishing: 89] [Article Influence: 6.2] [Reference Citation Analysis]
143 Tu S, Mcstay GP, Boucher L, Mak T, Beere HM, Green DR. In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis. Nat Cell Biol 2006;8:72-7. [DOI: 10.1038/ncb1340] [Cited by in Crossref: 143] [Cited by in F6Publishing: 137] [Article Influence: 8.4] [Reference Citation Analysis]
144 Twiddy D, Cohen GM, Macfarlane M, Cain K. Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex. J Biol Chem 2006;281:3876-88. [PMID: 16352606 DOI: 10.1074/jbc.M507393200] [Cited by in Crossref: 41] [Cited by in F6Publishing: 35] [Article Influence: 2.4] [Reference Citation Analysis]
145 Eckelman BP, Salvesen GS. The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J Biol Chem 2006;281:3254-60. [PMID: 16339151 DOI: 10.1074/jbc.M510863200] [Cited by in Crossref: 254] [Cited by in F6Publishing: 252] [Article Influence: 14.9] [Reference Citation Analysis]
146 Karki P, Lee J, Shin SY, Cho B, Park IS. Kinetic comparison of procaspase-3 and caspase-3. Arch Biochem Biophys 2005;442:125-32. [PMID: 16140256 DOI: 10.1016/j.abb.2005.07.023] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
147 Park IS, Kim JE. Potassium efflux during apoptosis. J Biochem Mol Biol 2002;35:41-6. [PMID: 16248968 DOI: 10.5483/bmbrep.2002.35.1.041] [Cited by in Crossref: 11] [Cited by in F6Publishing: 15] [Article Influence: 0.6] [Reference Citation Analysis]
148 Ho P, Hawkins CJ. Mammalian initiator apoptotic caspases. FEBS Journal 2005;272:5436-53. [DOI: 10.1111/j.1742-4658.2005.04966.x] [Cited by in Crossref: 117] [Cited by in F6Publishing: 113] [Article Influence: 6.9] [Reference Citation Analysis]
149 Nutku E, Hudson SA, Bochner BS. Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injury. Biochem Biophys Res Commun 2005;336:918-24. [PMID: 16157303 DOI: 10.1016/j.bbrc.2005.08.202] [Cited by in Crossref: 76] [Cited by in F6Publishing: 69] [Article Influence: 4.5] [Reference Citation Analysis]
150 Kornbluth S, White K. Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm). J Cell Sci 2005;118:1779-87. [PMID: 15860727 DOI: 10.1242/jcs.02377] [Cited by in Crossref: 131] [Cited by in F6Publishing: 131] [Article Influence: 7.7] [Reference Citation Analysis]
151 Meyer K, Basu A, Saito K, Ray RB, Ray R. Inhibition of hepatitis C virus core protein expression in immortalized human hepatocytes induces cytochrome c-independent increase in Apaf-1 and caspase-9 activation for cell death. Virology 2005;336:198-207. [PMID: 15892961 DOI: 10.1016/j.virol.2005.03.016] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 0.8] [Reference Citation Analysis]
152 Obeng EA, Boise LH. Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis. J Biol Chem. 2005;280:29578-29587. [PMID: 15975932 DOI: 10.1074/jbc.M502685200] [Cited by in Crossref: 124] [Cited by in F6Publishing: 117] [Article Influence: 7.3] [Reference Citation Analysis]
153 Lemaire C, Godefroy N, Costina-Parvu I, Rincheval V, Renaud F, Trotot P, Bouleau S, Mignotte B, Vayssière JL. Caspase-9 can antagonize p53-induced apoptosis by generating a p76(Rb) truncated form of Rb. Oncogene. 2005;24:3297-3308. [PMID: 15735701 DOI: 10.1038/sj.onc.1208493] [Cited by in Crossref: 14] [Cited by in F6Publishing: 17] [Article Influence: 0.8] [Reference Citation Analysis]
154 Crow MT, Mani K, Nam YJ, Kitsis RN. The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 2004;95:957-70. [PMID: 15539639 DOI: 10.1161/01.RES.0000148632.35500.d9] [Cited by in Crossref: 402] [Cited by in F6Publishing: 382] [Article Influence: 23.6] [Reference Citation Analysis]
155 Dahmer MK. Caspases-2, -3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells. J Neurosci Res 2005;80:576-83. [DOI: 10.1002/jnr.20471] [Cited by in Crossref: 44] [Cited by in F6Publishing: 45] [Article Influence: 2.6] [Reference Citation Analysis]
156 Fuentes-Prior P, Salvesen GS. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem J. 2004;384:201-232. [PMID: 15450003 DOI: 10.1042/bj20041142] [Cited by in Crossref: 567] [Cited by in F6Publishing: 550] [Article Influence: 33.4] [Reference Citation Analysis]
157 Stefanis L. Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury. Neuroscientist 2005;11:50-62. [PMID: 15632278 DOI: 10.1177/1073858404271087] [Cited by in Crossref: 95] [Cited by in F6Publishing: 85] [Article Influence: 5.6] [Reference Citation Analysis]
158 Piana S, Taylor Z, Rothlisberger U. Folding pathways for initiator and effector procaspases from computer simulations. Proteins 2005;59:765-72. [DOI: 10.1002/prot.20451] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.2] [Reference Citation Analysis]
159 Chin MY, Ng KCP, Li G. The novel tumor suppressor p33ING2 enhances UVB-induced apoptosis in human melanoma cells. Experimental Cell Research 2005;304:531-43. [DOI: 10.1016/j.yexcr.2004.11.023] [Cited by in Crossref: 25] [Cited by in F6Publishing: 22] [Article Influence: 1.5] [Reference Citation Analysis]
160 Tsang WP, Ho FY, Fung KP, Kong SK, Kwok TT. p53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis. Int J Cancer 2005;114:331-6. [PMID: 15578696 DOI: 10.1002/ijc.20818] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 1.4] [Reference Citation Analysis]
161 Cornelis S, Bruynooghe Y, Van Loo G, Saelens X, Vandenabeele P, Beyaert R. Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1. Oncogene 2005;24:1552-62. [PMID: 15674327 DOI: 10.1038/sj.onc.1208401] [Cited by in Crossref: 20] [Cited by in F6Publishing: 21] [Article Influence: 1.2] [Reference Citation Analysis]
162 Czerski L, Nuñez G. Apoptosome formation and caspase activation: is it different in the heart? J Mol Cell Cardiol 2004;37:643-52. [PMID: 15350837 DOI: 10.1016/j.yjmcc.2004.04.016] [Cited by in Crossref: 45] [Cited by in F6Publishing: 42] [Article Influence: 2.6] [Reference Citation Analysis]
163 Siu PM, Alway SE. Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle. J Physiol. 2005;565:309-323. [PMID: 15774533 DOI: 10.1113/jphysiol.2004.081083] [Cited by in Crossref: 147] [Cited by in F6Publishing: 155] [Article Influence: 8.6] [Reference Citation Analysis]
164 Lee W, Kim DH, Boo JH, Kim YH, Park I, Mook-jung I. ER stress-induced caspase-12 activation is inhibited by PKC in neuronal cells. Apoptosis 2005;10:407-15. [DOI: 10.1007/s10495-005-0814-6] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 0.9] [Reference Citation Analysis]
165 Kornblau SM, Konopleva M, Andreeff M. Apoptosis regulating proteins as targets of therapy for haematological malignancies. Expert Opinion on Investigational Drugs 2005;8:2027-57. [DOI: 10.1517/13543784.8.12.2027] [Cited by in Crossref: 14] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
166 Straathof KC, Pulè MA, Yotnda P, Dotti G, Vanin EF, Brenner MK, Heslop HE, Spencer DM, Rooney CM. An inducible caspase 9 safety switch for T-cell therapy. Blood. 2005;105:4247-4254. [PMID: 15728125 DOI: 10.1182/blood-2004-11-4564] [Cited by in Crossref: 419] [Cited by in F6Publishing: 413] [Article Influence: 24.6] [Reference Citation Analysis]
167 Tang CH, Hu CC, Wei CW, Wang JJ. Synergism of Rana catesbeiana ribonuclease and IFN-gamma triggers distinct death machineries in different human cancer cells. FEBS Lett 2005;579:265-70. [PMID: 15620724 DOI: 10.1016/j.febslet.2004.11.086] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 1.1] [Reference Citation Analysis]
168 Shi Y. Caspase activation, inhibition, and reactivation: a mechanistic view. Protein Sci 2004;13:1979-87. [PMID: 15273300 DOI: 10.1110/ps.04789804] [Cited by in Crossref: 189] [Cited by in F6Publishing: 186] [Article Influence: 11.1] [Reference Citation Analysis]
169 Liu H, Chang DW, Yang X. Interdimer processing and linearity of procaspase-3 activation. A unifying mechanism for the activation of initiator and effector caspases. J Biol Chem 2005;280:11578-82. [PMID: 15664982 DOI: 10.1074/jbc.M414385200] [Cited by in Crossref: 29] [Cited by in F6Publishing: 29] [Article Influence: 1.7] [Reference Citation Analysis]
170 Raina D, Pandey P, Ahmad R, Bharti A, Ren J, Kharbanda S, Weichselbaum R, Kufe D. c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem 2005;280:11147-51. [PMID: 15657060 DOI: 10.1074/jbc.M413787200] [Cited by in Crossref: 41] [Cited by in F6Publishing: 38] [Article Influence: 2.4] [Reference Citation Analysis]
171 Wright KM, Linhoff MW, Potts PR, Deshmukh M. Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis. J Cell Biol 2004;167:303-13. [PMID: 15504912 DOI: 10.1083/jcb.200406073] [Cited by in Crossref: 63] [Cited by in F6Publishing: 66] [Article Influence: 3.5] [Reference Citation Analysis]
172 Bose K, Clark AC. pH effects on the stability and dimerization of procaspase-3. Protein Sci 2005;14:24-36. [PMID: 15576551 DOI: 10.1110/ps.041003305] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 0.9] [Reference Citation Analysis]
173 Califice S, Castronovo V, Bracke M, van den Brûle F. Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3. Oncogene. 2004;23:7527-7536. [PMID: 15326483 DOI: 10.1038/sj.onc.1207997] [Cited by in Crossref: 120] [Cited by in F6Publishing: 111] [Article Influence: 6.7] [Reference Citation Analysis]
174 De Falco M, Fedele V, Cobellis L, Mastrogiacomo A, Leone S, Giraldi D, De Luca B, Laforgia V, De Luca A. Immunohistochemical distribution of proteins belonging to the receptor-mediated and the mitochondrial apoptotic pathways in human placenta during gestation. Cell Tissue Res 2004;318:599-608. [PMID: 15578274 DOI: 10.1007/s00441-004-0969-4] [Cited by in Crossref: 24] [Cited by in F6Publishing: 21] [Article Influence: 1.3] [Reference Citation Analysis]
175 Muro I, Monser K, Clem RJ. Mechanism of Dronc activation in Drosophila cells. Journal of Cell Science 2004;117:5035-41. [DOI: 10.1242/jcs.01376] [Cited by in Crossref: 55] [Cited by in F6Publishing: 49] [Article Influence: 3.1] [Reference Citation Analysis]
176 Dirks AJ, Leeuwenburgh C. Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free Radic Biol Med 2004;36:27-39. [PMID: 14732288 DOI: 10.1016/j.freeradbiomed.2003.10.003] [Cited by in Crossref: 149] [Cited by in F6Publishing: 142] [Article Influence: 8.3] [Reference Citation Analysis]
177 Carroll WL, Bhojwani D, Min DJ, Raetz E, Relling M, Davies S, Downing JR, Willman CL, Reed JC. Pediatric acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program. 2003;102-131. [PMID: 14633779 DOI: 10.1182/asheducation-2003.1.102] [Cited by in Crossref: 74] [Cited by in F6Publishing: 74] [Article Influence: 4.1] [Reference Citation Analysis]
178 Wilkinson JC, Cepero E, Boise LH, Duckett CS. Upstream regulatory role for XIAP in receptor-mediated apoptosis. Mol Cell Biol 2004;24:7003-14. [PMID: 15282301 DOI: 10.1128/MCB.24.16.7003-7014.2004] [Cited by in Crossref: 82] [Cited by in F6Publishing: 74] [Article Influence: 4.6] [Reference Citation Analysis]
179 Cain K. Chemical-induced apoptosis: formation of the Apaf-1 apoptosome. Drug Metab Rev. 2003;35:337-363. [PMID: 14705865 DOI: 10.1081/DMR-120026497] [Cited by in Crossref: 51] [Cited by in F6Publishing: 47] [Article Influence: 2.8] [Reference Citation Analysis]
180 Boatright KM, Salvesen GS. Mechanisms of caspase activation. Curr Opin Cell Biol 2003;15:725-31. [PMID: 14644197 DOI: 10.1016/j.ceb.2003.10.009] [Cited by in Crossref: 885] [Cited by in F6Publishing: 855] [Article Influence: 49.2] [Reference Citation Analysis]
181 Wang T, Chen F, Chen Z, Wu YF, Xu XL, Zheng S, Hu X. Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO. World J Gastroenterol 2004; 10(15): 2205-2208 [PMID: 15259066 DOI: 10.3748/wjg.v10.i15.2205] [Cited by in CrossRef: 94] [Cited by in F6Publishing: 76] [Article Influence: 5.2] [Reference Citation Analysis]
182 Wagner KW, Engels IH, Deveraux QL. Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway. J Biol Chem 2004;279:35047-52. [PMID: 15173176 DOI: 10.1074/jbc.M400708200] [Cited by in Crossref: 90] [Cited by in F6Publishing: 87] [Article Influence: 5.0] [Reference Citation Analysis]
183 Hildesheim J, Fornace AJ. The dark side of light: the damaging effects of UV rays and the protective efforts of MAP kinase signaling in the epidermis. DNA Repair 2004;3:567-80. [DOI: 10.1016/j.dnarep.2004.02.012] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 0.9] [Reference Citation Analysis]
184 Shi Y. Caspase Activation. Cell 2004;117:855-8. [DOI: 10.1016/j.cell.2004.06.007] [Cited by in Crossref: 234] [Cited by in F6Publishing: 209] [Article Influence: 13.0] [Reference Citation Analysis]
185 Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B. Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell. 2004;5:25-35. [PMID: 14749124 DOI: 10.1016/S1535-6108(03)00332-5] [Cited by in Crossref: 312] [Cited by in F6Publishing: 264] [Article Influence: 17.3] [Reference Citation Analysis]
186 Saelens X, Festjens N, Vande Walle L, van Gurp M, van Loo G, Vandenabeele P. Toxic proteins released from mitochondria in cell death. Oncogene. 2004;23:2861-2874. [PMID: 15077149 DOI: 10.1038/sj.onc.1207523] [Cited by in Crossref: 582] [Cited by in F6Publishing: 554] [Article Influence: 32.3] [Reference Citation Analysis]
187 Salvesen GS, Abrams JM. Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies. Oncogene 2004;23:2774-84. [PMID: 15077141 DOI: 10.1038/sj.onc.1207522] [Cited by in Crossref: 180] [Cited by in F6Publishing: 177] [Article Influence: 10.0] [Reference Citation Analysis]
188 Vera Y, Diaz-romero M, Rodriguez S, Lue Y, Wang C, Swerdloff RS, Sinha Hikim AP. Mitochondria-Dependent Pathway Is Involved in Heat-Induced Male Germ Cell Death: Lessons from Mutant Mice1. Biology of Reproduction 2004;70:1534-40. [DOI: 10.1095/biolreprod.103.024661] [Cited by in Crossref: 69] [Cited by in F6Publishing: 69] [Article Influence: 3.8] [Reference Citation Analysis]
189 Li P, Nijhawan D, Wang X. Mitochondrial activation of apoptosis. Cell 2004;116:S57-9, 2 p following S59. [PMID: 15055583 DOI: 10.1016/s0092-8674(04)00031-5] [Cited by in Crossref: 79] [Cited by in F6Publishing: 78] [Article Influence: 4.4] [Reference Citation Analysis]
190 Droin NM, Green DR. Role of Bcl-2 family members in immunity and disease. Biochim Biophys Acta 2004;1644:179-88. [PMID: 14996502 DOI: 10.1016/j.bbamcr.2003.10.011] [Cited by in Crossref: 43] [Cited by in F6Publishing: 40] [Article Influence: 2.4] [Reference Citation Analysis]
191 Sanchis D, Mayorga M, Ballester M, Comella JX. Lack of Apaf-1 expression confers resistance to cytochrome c-driven apoptosis in cardiomyocytes. Cell Death Differ 2003;10:977-86. [PMID: 12934072 DOI: 10.1038/sj.cdd.4401267] [Cited by in Crossref: 51] [Cited by in F6Publishing: 49] [Article Influence: 2.8] [Reference Citation Analysis]
192 Twiddy D, Brown DG, Adrain C, Jukes R, Martin SJ, Cohen GM, MacFarlane M, Cain K. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex. J Biol Chem. 2004;279:19665-19682. [PMID: 14993223 DOI: 10.1074/jbc.M311388200] [Cited by in Crossref: 72] [Cited by in F6Publishing: 73] [Article Influence: 4.0] [Reference Citation Analysis]
193 Festjens N, van Gurp M, van Loo G, Saelens X, Vandenabeele P. Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death. Acta Haematol 2004;111:7-27. [PMID: 14646342 DOI: 10.1159/000074483] [Cited by in Crossref: 70] [Cited by in F6Publishing: 64] [Article Influence: 3.9] [Reference Citation Analysis]
194 Hoetelmans RW, Van de Velde CJ, Van Dierendonck JH. The presence of 19-kDa Bcl-2 in dividing cells. Cell Prolif 2003;36:293-306. [PMID: 14710848 DOI: 10.1046/j.1365-2184.2003.00286.x] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 0.3] [Reference Citation Analysis]
195 Crnkovic-Mertens I, Hoppe-Seyler F, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene. 2003;22:8330-8336. [PMID: 14614456 DOI: 10.1038/sj.onc.1206973] [Cited by in Crossref: 69] [Cited by in F6Publishing: 62] [Article Influence: 3.8] [Reference Citation Analysis]
196 Kim JE, Tannenbaum SR. S-Nitrosation regulates the activation of endogenous procaspase-9 in HT-29 human colon carcinoma cells. J Biol Chem 2004;279:9758-64. [PMID: 14701803 DOI: 10.1074/jbc.M312722200] [Cited by in Crossref: 56] [Cited by in F6Publishing: 50] [Article Influence: 2.9] [Reference Citation Analysis]
197 Troy CM, Shelanski ML. Caspase-2 redux. Cell Death Differ 2003;10:101-7. [PMID: 12655298 DOI: 10.1038/sj.cdd.4401175] [Cited by in Crossref: 94] [Cited by in F6Publishing: 95] [Article Influence: 4.9] [Reference Citation Analysis]
198 Bose K, Pop C, Feeney B, Clark AC. An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3. Biochemistry 2003;42:12298-310. [PMID: 14567691 DOI: 10.1021/bi034998x] [Cited by in Crossref: 53] [Cited by in F6Publishing: 48] [Article Influence: 2.8] [Reference Citation Analysis]
199 Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene 2003;22:8543-67. [DOI: 10.1038/sj.onc.1207107] [Cited by in Crossref: 754] [Cited by in F6Publishing: 720] [Article Influence: 39.7] [Reference Citation Analysis]
200 Kashkar H, Haefs C, Shin H, Hamilton-Dutoit SJ, Salvesen GS, Kronke M, Jurgensmeier JM. XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells. J Exp Med 2003;198:341-7. [PMID: 12874265 DOI: 10.1084/jem.20021279] [Cited by in Crossref: 99] [Cited by in F6Publishing: 86] [Article Influence: 5.2] [Reference Citation Analysis]
201 Mcdonnell MA, Wang D, Khan SM, Vander Heiden MG, Kelekar A. Caspase-9 is activated in a cytochrome c-independent manner early during TNFα-induced apoptosis in murine cells. Cell Death Differ 2003;10:1005-15. [DOI: 10.1038/sj.cdd.4401271] [Cited by in Crossref: 71] [Cited by in F6Publishing: 70] [Article Influence: 3.7] [Reference Citation Analysis]
202 Sattar R, Ali S, Abbasi A. Molecular mechanism of apoptosis: prediction of three-dimensional structure of caspase-6 and its interactions by homology modeling. Biochemical and Biophysical Research Communications 2003;308:497-504. [DOI: 10.1016/s0006-291x(03)01394-9] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 0.6] [Reference Citation Analysis]
203 Pollett JB, Zhu Y, Gandhi S, Bali M, Masih-khan E, Li Z, Wen X, Stewart A. RU486-inducible retrovirus-mediated caspase-3 overexpression is cytotoxic to bcl-xl-expressing myeloma cells in vitro and in vivo. Molecular Therapy 2003;8:230-7. [DOI: 10.1016/s1525-0016(03)00146-1] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
204 Kim TW, Hung CF, Ling M, Juang J, He L, Hardwick JM, Kumar S, Wu TC. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J Clin Invest. 2003;112:109-117. [PMID: 12840065 DOI: 10.1172/jci17293] [Cited by in Crossref: 5] [Cited by in F6Publishing: 59] [Article Influence: 0.3] [Reference Citation Analysis]
205 Marusawa H, Matsuzawa S, Welsh K, Zou H, Armstrong R, Tamm I, Reed JC. HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J. 2003;22:2729-2740. [PMID: 12773388 DOI: 10.1093/emboj/cdg263] [Cited by in Crossref: 305] [Cited by in F6Publishing: 309] [Article Influence: 16.1] [Reference Citation Analysis]
206 Kim TW, Hung C, Ling M, Juang J, He L, Hardwick JM, Kumar S, Wu T. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J Clin Invest 2003;112:109-17. [DOI: 10.1172/jci200317293] [Cited by in Crossref: 136] [Cited by in F6Publishing: 71] [Article Influence: 7.2] [Reference Citation Analysis]
207 Ryan CA, Salvesen GS. Caspases and Neuronal Development. Biological Chemistry 2003;384:855-61. [DOI: 10.1515/bc.2003.096] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 0.5] [Reference Citation Analysis]
208 Ferrer M, Izeboud T, Ferreira CG, Span SW, Giaccone G, Kruyt FA. Cisplatin triggers apoptotic or nonapoptotic cell death in Fanconi anemia lymphoblasts in a concentration-dependent manner. Experimental Cell Research 2003;286:381-95. [DOI: 10.1016/s0014-4827(03)00112-5] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 0.8] [Reference Citation Analysis]
209 Potokar M, Milisav I, Kreft M, Stenovec M, Zorec R. Apoptosis triggered redistribution of caspase-9 from cytoplasm to mitochondria. FEBS Letters 2003;544:153-9. [DOI: 10.1016/s0014-5793(03)00494-0] [Cited by in Crossref: 20] [Cited by in F6Publishing: 22] [Article Influence: 1.1] [Reference Citation Analysis]
210 Lakhani S, Flavell RA. Caspases and T lymphocytes: a flip of the coin?: Lakhani et al · Caspases and T lymphocytes. Immunological Reviews 2003;193:22-30. [DOI: 10.1034/j.1600-065x.2003.00046.x] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 0.7] [Reference Citation Analysis]
211 Chang DW, Ditsworth D, Liu H, Srinivasula SM, Alnemri ES, Yang X. Oligomerization Is a General Mechanism for the Activation of Apoptosis Initiator and Inflammatory Procaspases. Journal of Biological Chemistry 2003;278:16466-9. [DOI: 10.1074/jbc.c300089200] [Cited by in Crossref: 57] [Cited by in F6Publishing: 47] [Article Influence: 3.0] [Reference Citation Analysis]
212 Donepudi M, Mac Sweeney A, Briand C, Grütter MG. Insights into the regulatory mechanism for caspase-8 activation. Mol Cell 2003;11:543-9. [PMID: 12620240 DOI: 10.1016/s1097-2765(03)00059-5] [Cited by in Crossref: 206] [Cited by in F6Publishing: 177] [Article Influence: 10.8] [Reference Citation Analysis]
213 Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM, Ricci JE, Edris WA, Sutherlin DP, Green DR, Salvesen GS. A unified model for apical caspase activation. Mol Cell 2003;11:529-41. [PMID: 12620239 DOI: 10.1016/s1097-2765(03)00051-0] [Cited by in Crossref: 675] [Cited by in F6Publishing: 593] [Article Influence: 35.5] [Reference Citation Analysis]
214 Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C, Brancolini C. Role of Caspases, Bid, and p53 in the Apoptotic Response Triggered by Histone Deacetylase Inhibitors Trichostatin-A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA). Journal of Biological Chemistry 2003;278:12579-89. [DOI: 10.1074/jbc.m213093200] [Cited by in Crossref: 119] [Cited by in F6Publishing: 102] [Article Influence: 6.3] [Reference Citation Analysis]
215 Caballero-Benítez A, Morán J. Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2. J Neurosci Res 2003;71:383-96. [PMID: 12526027 DOI: 10.1002/jnr.10493] [Cited by in Crossref: 34] [Cited by in F6Publishing: 34] [Article Influence: 1.8] [Reference Citation Analysis]
216 Pfister Y, Savioz A, Vallet P, Dubois-dauphin M. Permanent cerebral ischemia induces sustained procaspase 9L increase not controlled by Bcl-2. Brain Research 2003;966:26-39. [DOI: 10.1016/s0006-8993(02)04147-1] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.3] [Reference Citation Analysis]
217 Sutton VR, Wowk ME, Cancilla M, Trapani JA. Caspase Activation by Granzyme B Is Indirect, and Caspase Autoprocessing Requires the Release of Proapoptotic Mitochondrial Factors. Immunity 2003;18:319-29. [DOI: 10.1016/s1074-7613(03)00050-5] [Cited by in Crossref: 120] [Cited by in F6Publishing: 109] [Article Influence: 6.3] [Reference Citation Analysis]
218 Zou H, Yang R, Hao J, Wang J, Sun C, Fesik SW, Wu JC, Tomaselli KJ, Armstrong RC. Regulation of the Apaf-1/Caspase-9 Apoptosome by Caspase-3 and XIAP. Journal of Biological Chemistry 2003;278:8091-8. [DOI: 10.1074/jbc.m204783200] [Cited by in Crossref: 158] [Cited by in F6Publishing: 140] [Article Influence: 8.3] [Reference Citation Analysis]
219 Mikolajczyk J, Boatright KM, Stennicke HR, Nazif T, Potempa J, Bogyo M, Salvesen GS. Sequential Autolytic Processing Activates the Zymogen of Arg-gingipain. Journal of Biological Chemistry 2003;278:10458-64. [DOI: 10.1074/jbc.m210564200] [Cited by in Crossref: 49] [Cited by in F6Publishing: 52] [Article Influence: 2.6] [Reference Citation Analysis]
220 Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis. Cell Death Differ. 2002;9:881-892. [PMID: 12181739 DOI: 10.1038/sj.cdd.4401069] [Cited by in Crossref: 88] [Cited by in F6Publishing: 89] [Article Influence: 4.6] [Reference Citation Analysis]
221 Read SH, Baliga BC, Ekert PG, Vaux DL, Kumar S. A novel Apaf-1-independent putative caspase-2 activation complex. J Cell Biol 2002;159:739-45. [PMID: 12460989 DOI: 10.1083/jcb.200209004] [Cited by in Crossref: 124] [Cited by in F6Publishing: 113] [Article Influence: 6.2] [Reference Citation Analysis]
222 Adams JM, Cory S. Apoptosomes: engines for caspase activation. Current Opinion in Cell Biology 2002;14:715-20. [DOI: 10.1016/s0955-0674(02)00381-2] [Cited by in Crossref: 199] [Cited by in F6Publishing: 185] [Article Influence: 10.0] [Reference Citation Analysis]
223 Ryan CA, Stennicke HR, Nava VE, Burch JB, Hardwick JM, Salvesen GS. Inhibitor specificity of recombinant and endogenous caspase-9. Biochem J 2002;366:595-601. [PMID: 12067274 DOI: 10.1042/BJ20020863] [Cited by in Crossref: 29] [Cited by in F6Publishing: 23] [Article Influence: 1.5] [Reference Citation Analysis]
224 Salgado J, García-sáez AJ, Malet G, Mingarro I, Pérez-payá E. Peptides in apoptosis research: PEPTIDES IN APOPTOSIS RESEARCH. J Peptide Sci 2002;8:543-60. [DOI: 10.1002/psc.414] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.4] [Reference Citation Analysis]
225 van der Kolk L, Evers L, Omene C, Lens S, Lederman S, van Lier R, van Oers M, Eldering E. CD20-induced B cell death can bypass mitochondria and caspase activation. Leukemia 2002;16:1735-44. [DOI: 10.1038/sj.leu.2402559] [Cited by in Crossref: 62] [Cited by in F6Publishing: 56] [Article Influence: 3.1] [Reference Citation Analysis]
226 Schauvliege R, Vanrobaeys J, Schotte P, Beyaert R. Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-kappa B and signal transducer and activator of transcription (STAT) 1. J Biol Chem 2002;277:41624-30. [PMID: 12198138 DOI: 10.1074/jbc.M207852200] [Cited by in Crossref: 109] [Cited by in F6Publishing: 108] [Article Influence: 5.5] [Reference Citation Analysis]
227 Kang BH, Ko E, Kwon OK, Choi KY. The structure of procaspase 6 is similar to that of active mature caspase 6. Biochem J 2002;364:629-34. [PMID: 12049625 DOI: 10.1042/BJ20011787] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 0.8] [Reference Citation Analysis]
228 Troy CM, Salvesen GS. Caspases on the brain. J Neurosci Res 2002;69:145-50. [PMID: 12111795 DOI: 10.1002/jnr.10294] [Cited by in Crossref: 79] [Cited by in F6Publishing: 81] [Article Influence: 4.0] [Reference Citation Analysis]
229 Chien AJ, Presland RB, Kuechle MK. Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation. Biochemical and Biophysical Research Communications 2002;296:911-7. [DOI: 10.1016/s0006-291x(02)02015-6] [Cited by in Crossref: 33] [Cited by in F6Publishing: 29] [Article Influence: 1.7] [Reference Citation Analysis]
230 Luu Y, Bush J, Cheung KJ, Li G. The p53 stabilizing compound CP-31398 induces apoptosis by activating the intrinsic Bax/mitochondrial/caspase-9 pathway. Exp Cell Res. 2002;276:214-222. [PMID: 12027451 DOI: 10.1006/excr.2002.5526] [Cited by in Crossref: 61] [Cited by in F6Publishing: 57] [Article Influence: 3.1] [Reference Citation Analysis]
231 Salvesen GS, Duckett CS. IAP proteins: blocking the road to death’s door. Nat Rev Mol Cell Biol. 2002;3:401-410. [PMID: 12042762 DOI: 10.1038/nrm830] [Cited by in Crossref: 1242] [Cited by in F6Publishing: 1169] [Article Influence: 62.1] [Reference Citation Analysis]
232 Little SA, Mirkes PE. Teratogen-Induced Activation of Caspase-9 and the Mitochondrial Apoptotic Pathway in Early Postimplantation Mouse Embryos. Toxicology and Applied Pharmacology 2002;181:142-51. [DOI: 10.1006/taap.2002.9414] [Cited by in Crossref: 25] [Cited by in F6Publishing: 22] [Article Influence: 1.3] [Reference Citation Analysis]
233 Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell. 2002;9:459-470. [PMID: 11931755 DOI: 10.1016/s1097-2765(02)00482-3] [Cited by in Crossref: 1123] [Cited by in F6Publishing: 1086] [Article Influence: 56.2] [Reference Citation Analysis]
234 Herold MJ, Kuss AW, Kraus C, Berberich I. Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells. J Immunol. 2002;168:3902-3909. [PMID: 11937545 DOI: 10.4049/jimmunol.168.8.3902] [Cited by in Crossref: 40] [Cited by in F6Publishing: 40] [Article Influence: 2.0] [Reference Citation Analysis]
235 Teitz T, Wei T, Liu D, Valentine V, Valentine M, Grenet J, Lahti JM, Kidd VJ. Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN. Oncogene 2002;21:1848-58. [PMID: 11896617 DOI: 10.1038/sj.onc.1205180] [Cited by in Crossref: 32] [Cited by in F6Publishing: 29] [Article Influence: 1.6] [Reference Citation Analysis]
236 Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, Akey CW. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell. 2002;9:423-432. [PMID: 11864614 DOI: 10.1016/s1097-2765(02)00442-2] [Cited by in Crossref: 567] [Cited by in F6Publishing: 501] [Article Influence: 28.4] [Reference Citation Analysis]
237 Sitailo LA, Tibudan SS, Denning MF. Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes. J Biol Chem. 2002;277:19346-19352. [PMID: 11919192 DOI: 10.1074/jbc.m200401200] [Cited by in Crossref: 112] [Cited by in F6Publishing: 106] [Article Influence: 5.6] [Reference Citation Analysis]
238 Shiozaki EN, Chai J, Shi Y. Oligomerization and activation of caspase-9, induced by Apaf-1 CARD. Proc Natl Acad Sci U S A 2002;99:4197-202. [PMID: 11904389 DOI: 10.1073/pnas.072544399] [Cited by in Crossref: 97] [Cited by in F6Publishing: 89] [Article Influence: 4.9] [Reference Citation Analysis]
239 Zimmermann KC, Bonzon C, Green DR. The machinery of programmed cell death. Pharmacol Ther. 2001;92:57-70. [PMID: 11750036 DOI: 10.1016/s0163-7258(01)00159-0] [Cited by in Crossref: 551] [Cited by in F6Publishing: 533] [Article Influence: 27.6] [Reference Citation Analysis]
240 Shi Y. Apoptosome. Structure 2002;10:285-8. [DOI: 10.1016/s0969-2126(02)00732-3] [Cited by in Crossref: 80] [Cited by in F6Publishing: 69] [Article Influence: 4.0] [Reference Citation Analysis]
241 Cain K, Bratton SB, Cohen GM. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie 2002;84:203-14. [DOI: 10.1016/s0300-9084(02)01376-7] [Cited by in Crossref: 278] [Cited by in F6Publishing: 260] [Article Influence: 13.9] [Reference Citation Analysis]
242 Green DR, Evan GI. A matter of life and death. Cancer Cell 2002;1:19-30. [DOI: 10.1016/s1535-6108(02)00024-7] [Cited by in Crossref: 740] [Cited by in F6Publishing: 682] [Article Influence: 37.0] [Reference Citation Analysis]
243 Riedl SJ, Fuentes-Prior P, Renatus M, Kairies N, Krapp S, Huber R, Salvesen GS, Bode W. Structural basis for the activation of human procaspase-7. Proc Natl Acad Sci USA. 2001;98:14790-14795. [PMID: 11752425 DOI: 10.1073/pnas.221580098] [Cited by in Crossref: 158] [Cited by in F6Publishing: 147] [Article Influence: 7.9] [Reference Citation Analysis]
244 Costantini P, Bruey J, Castedo M, Métivier D, Loeffler M, Susin SA, Ravagnan L, Zamzami N, Garrido C, Kroemer G. Pre-processed caspase-9 contained in mitochondria participates in apoptosis. Cell Death Differ 2002;9:82-8. [DOI: 10.1038/sj.cdd.4400932] [Cited by in Crossref: 53] [Cited by in F6Publishing: 54] [Article Influence: 2.7] [Reference Citation Analysis]
245 Pop C, Chen YR, Smith B, Bose K, Bobay B, Tripathy A, Franzen S, Clark AC. Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer. Biochemistry 2001;40:14224-35. [PMID: 11714276 DOI: 10.1021/bi011037e] [Cited by in Crossref: 48] [Cited by in F6Publishing: 52] [Article Influence: 2.4] [Reference Citation Analysis]
246 Renatus M, Stennicke HR, Scott FL, Liddington RC, Salvesen GS. Dimer formation drives the activation of the cell death protease caspase 9. Proc Natl Acad Sci U S A 2001;98:14250-5. [PMID: 11734640 DOI: 10.1073/pnas.231465798] [Cited by in Crossref: 307] [Cited by in F6Publishing: 289] [Article Influence: 15.4] [Reference Citation Analysis]
247 Chai J, Wu Q, Shiozaki E, Srinivasula SM, Alnemri ES, Shi Y. Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding. Cell. 2001;107:399-407. [PMID: 11701129 DOI: 10.1016/s0092-8674(01)00544-x] [Cited by in Crossref: 172] [Cited by in F6Publishing: 158] [Article Influence: 8.2] [Reference Citation Analysis]
248 Dewson G, Cohen GM, Wardlaw AJ. Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils. Blood 2001;98:2239-47. [PMID: 11568012 DOI: 10.1182/blood.v98.7.2239] [Cited by in Crossref: 59] [Cited by in F6Publishing: 58] [Article Influence: 2.8] [Reference Citation Analysis]
249 U M, Miyashita T, Ohtsuka Y, Okamura-Oho Y, Shikama Y, Yamada M. Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates. Cell Death Differ 2001;8:377-86. [PMID: 11550089 DOI: 10.1038/sj.cdd.4400819] [Cited by in Crossref: 24] [Cited by in F6Publishing: 25] [Article Influence: 1.1] [Reference Citation Analysis]
250 Wobser H, Düssmann H, Kögel D, Wang H, Reimertz C, Wollheim CB, Byrne MM, Prehn JH. Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. J Biol Chem 2002;277:6413-21. [PMID: 11724785 DOI: 10.1074/jbc.M108390200] [Cited by in Crossref: 46] [Cited by in F6Publishing: 38] [Article Influence: 2.2] [Reference Citation Analysis]
251 Zörnig M, Hueber A, Baum W, Evan G. Apoptosis regulators and their role in tumorigenesis. Biochim Biophys Acta. 2001;1551:F1-37. [PMID: 11591448 DOI: 10.1016/s0304-419x(01)00031-2] [Cited by in Crossref: 18] [Cited by in F6Publishing: 63] [Article Influence: 0.9] [Reference Citation Analysis]
252 Jones DT, Ganeshaguru K, Virchis AE, Folarin NI, Lowdell MW, Mehta AB, Prentice HG, Hoffbrand AV, Wickremasinghe RG. Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or γ radiation. Blood 2001;98:2800-7. [DOI: 10.1182/blood.v98.9.2800] [Cited by in Crossref: 50] [Cited by in F6Publishing: 49] [Article Influence: 2.4] [Reference Citation Analysis]
253 Shinoura N, Sakurai S, Asai A, Kirino T, Hamada H. Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U-87MG glioma cells. Neurosurgery 2001;49:177-86; discussion 186-7. [PMID: 11440440 DOI: 10.1097/00006123-200107000-00027] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
254 Bose K, Clark AC. Dimeric Procaspase-3 Unfolds via a Four-State Equilibrium Process. Biochemistry 2001;40:14236-42. [DOI: 10.1021/bi0110387] [Cited by in Crossref: 37] [Cited by in F6Publishing: 41] [Article Influence: 1.8] [Reference Citation Analysis]
255 Dubois-dauphin M, Pfister Y, Vallet P, Savioz A. Prevention of apoptotic neuronal death by controlling procaspases? A point of view. Brain Research Reviews 2001;36:196-203. [DOI: 10.1016/s0165-0173(01)00095-9] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 0.7] [Reference Citation Analysis]
256 Almond J, Snowden R, Hunter A, Dinsdale D, Cain K, Cohen G. Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an ∼700 kDa Apaf-1 containing apoptosome complex. Leukemia 2001;15:1388-97. [DOI: 10.1038/sj.leu.2402201] [Cited by in Crossref: 61] [Cited by in F6Publishing: 53] [Article Influence: 2.9] [Reference Citation Analysis]
257 Adrain C, Martin SJ. The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Trends Biochem Sci. 2001;26:390-397. [PMID: 11406413 DOI: 10.1016/s0968-0004(01)01844-8] [Cited by in Crossref: 363] [Cited by in F6Publishing: 339] [Article Influence: 17.3] [Reference Citation Analysis]
258 Jones C, Ciacci-Zanella JR, Zhang Y, Henderson G, Dickman M. Analysis of fumonisin B1-induced apoptosis. Environ Health Perspect 2001;109 Suppl 2:315-20. [PMID: 11359701 DOI: 10.1289/ehp.01109s2315] [Cited by in Crossref: 7] [Cited by in F6Publishing: 11] [Article Influence: 0.3] [Reference Citation Analysis]
259 Pardo J, Pérez-galán P, Gamen S, Marzo I, Monleón I, Kaspar AA, Susín SA, Kroemer G, Krensky AM, Naval J, Anel A. A Role of the Mitochondrial Apoptosis-Inducing Factor in Granulysin-Induced Apoptosis. J Immunol 2001;167:1222-9. [DOI: 10.4049/jimmunol.167.3.1222] [Cited by in Crossref: 84] [Cited by in F6Publishing: 83] [Article Influence: 4.0] [Reference Citation Analysis]
260 Kaufmann SH, Kottke TJ, Martins LM, Henzing AJ, Earnshaw WC. Analysis of Caspase Activation During Apoptosis. Current Protocols in Cell Biology 2001;11. [DOI: 10.1002/0471143030.cb1802s11] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
261 Silke J, Ekert PG, Day CL, Hawkins CJ, Baca M, Chew J, Pakusch M, Verhagen AM, Vaux DL. Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP. EMBO J 2001;20:3114-23. [PMID: 11406588 DOI: 10.1093/emboj/20.12.3114] [Cited by in Crossref: 81] [Cited by in F6Publishing: 77] [Article Influence: 3.9] [Reference Citation Analysis]
262 Richter BW, Mir SS, Eiben LJ, Lewis J, Reffey SB, Frattini A, Tian L, Frank S, Youle RJ, Nelson DL, Notarangelo LD, Vezzoni P, Fearnhead HO, Duckett CS. Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family. Mol Cell Biol 2001;21:4292-301. [PMID: 11390657 DOI: 10.1128/MCB.21.13.4292-4301.2001] [Cited by in Crossref: 69] [Cited by in F6Publishing: 66] [Article Influence: 3.3] [Reference Citation Analysis]
263 Meergans T, Hildebrandt AK, Horak D, Haenisch C, Wendel A. The short prodomain influences caspase-3 activation in HeLa cells. Biochem J. 2000;349:135-140. [PMID: 10861221 DOI: 10.1042/bj3490135] [Cited by in Crossref: 21] [Cited by in F6Publishing: 15] [Article Influence: 1.0] [Reference Citation Analysis]
264 Meergans T, Hildebrandt AK, Horak D, Haenisch C, Wendel A. The short prodomain influences caspase-3 activation in HeLa cells. Biochem J 2000;349:135-40. [PMID: 10861221 DOI: 10.1042/0264-6021:3490135] [Cited by in Crossref: 10] [Cited by in F6Publishing: 17] [Article Influence: 0.5] [Reference Citation Analysis]
265 Rao RV, Hermel E, Castro-Obregon S, del Rio G, Ellerby LM, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J Biol Chem. 2001;276:33869-33874. [PMID: 11448953 DOI: 10.1074/jbc.m102225200] [Cited by in Crossref: 422] [Cited by in F6Publishing: 407] [Article Influence: 20.1] [Reference Citation Analysis]
266 Kaspar AA, Okada S, Kumar J, Poulain FR, Drouvalakis KA, Kelekar A, Hanson DA, Kluck RM, Hitoshi Y, Johnson DE, Froelich CJ, Thompson CB, Newmeyer DD, Anel A, Clayberger C, Krensky AM. A Distinct Pathway of Cell-Mediated Apoptosis Initiated by Granulysin. J Immunol 2001;167:350-6. [DOI: 10.4049/jimmunol.167.1.350] [Cited by in Crossref: 104] [Cited by in F6Publishing: 98] [Article Influence: 5.0] [Reference Citation Analysis]
267 Navratil JS, Ahearn JM. Apoptosis, clearance mechanisms, and the development of systemic lupus erythematosus. Curr Rheumatol Rep 2001;3:191-8. [DOI: 10.1007/s11926-001-0018-1] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 1.2] [Reference Citation Analysis]
268 Paroni G, Henderson C, Schneider C, Brancolini C. Caspase-2-induced Apoptosis Is Dependent on Caspase-9, but Its Processing during UV- or Tumor Necrosis Factor-dependent Cell Death Requires Caspase-3. Journal of Biological Chemistry 2001;276:21907-15. [DOI: 10.1074/jbc.m011565200] [Cited by in Crossref: 74] [Cited by in F6Publishing: 73] [Article Influence: 3.5] [Reference Citation Analysis]
269 Drewett V, Devitt A, Saxton J, Portman N, Greaney P, Cheong NE, Alnemri TF, Alnemri E, Shaw PE. Serum response factor cleavage by caspases 3 and 7 linked to apoptosis in human BJAB cells. J Biol Chem 2001;276:33444-51. [PMID: 11387340 DOI: 10.1074/jbc.M103877200] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 1.0] [Reference Citation Analysis]
270 Lauber K, Appel HA, Schlosser SF, Gregor M, Schulze-Osthoff K, Wesselborg S. The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis. J Biol Chem 2001;276:29772-81. [PMID: 11387322 DOI: 10.1074/jbc.M101524200] [Cited by in Crossref: 60] [Cited by in F6Publishing: 56] [Article Influence: 2.9] [Reference Citation Analysis]
271 Huang Q, Deveraux QL, Maeda S, Stennicke HR, Hammock BD, Reed JC. Cloning and characterization of an inhibitor of apoptosis protein (IAP) from Bombyx mori. Biochim Biophys Acta 2001;1499:191-8. [PMID: 11341966 DOI: 10.1016/s0167-4889(00)00105-1] [Cited by in Crossref: 43] [Cited by in F6Publishing: 38] [Article Influence: 2.0] [Reference Citation Analysis]
272 Kraft C, Suerbaum S. Mutation and recombination in Helicobacter pylori: mechanisms and role in generating strain diversity. Int J Med Microbiol. 2005;295:299-305. [PMID: 11292739 DOI: 10.1128/iai.69.5.3181-3189.2001] [Cited by in Crossref: 42] [Cited by in F6Publishing: 44] [Article Influence: 2.0] [Reference Citation Analysis]
273 Fujita E, Egashira J, Urase K, Kuida K, Momoi T. Caspase-9 processing by caspase-3 via a feedback amplification loop in vivo. Cell Death Differ 2001;8:335-44. [DOI: 10.1038/sj.cdd.4400824] [Cited by in Crossref: 79] [Cited by in F6Publishing: 81] [Article Influence: 3.8] [Reference Citation Analysis]
274 Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES, Cohen GM. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. EMBO J 2001;20:998-1009. [PMID: 11230124 DOI: 10.1093/emboj/20.5.998] [Cited by in Crossref: 277] [Cited by in F6Publishing: 263] [Article Influence: 13.2] [Reference Citation Analysis]
275 Walke DW, Morgan JI. A comparison of the expression and properties of Apaf-1 and Apaf-1L. Brain Res 2000;886:73-81. [PMID: 11119689 DOI: 10.1016/s0006-8993(00)02916-4] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
276 Stoka V, Turk B, Schendel SL, Kim T, Cirman T, Snipas SJ, Ellerby LM, Bredesen D, Freeze H, Abrahamson M, Brömme D, Krajewski S, Reed JC, Yin X, Turk V, Salvesen GS. Lysosomal Protease Pathways to Apoptosis. Journal of Biological Chemistry 2001;276:3149-57. [DOI: 10.1074/jbc.m008944200] [Cited by in Crossref: 482] [Cited by in F6Publishing: 455] [Article Influence: 23.0] [Reference Citation Analysis]
277 Denault J, Salvesen GS. Caspases. Current Protocols in Protein Science 2001;26. [DOI: 10.1002/0471140864.ps2108s26] [Cited by in Crossref: 3] [Cited by in F6Publishing: 7] [Article Influence: 0.1] [Reference Citation Analysis]
278 Angelastro JM, Moon NY, Liu DX, Yang AS, Greene LA, Franke TF. Characterization of a novel isoform of caspase-9 that inhibits apoptosis. J Biol Chem 2001;276:12190-200. [PMID: 11278518 DOI: 10.1074/jbc.M009523200] [Cited by in Crossref: 29] [Cited by in F6Publishing: 31] [Article Influence: 1.4] [Reference Citation Analysis]
279 Chang HY, Yang X. Proteases for cell suicide: functions and regulation of caspases. Microbiol Mol Biol Rev. 2000;64:821-846. [PMID: 11104820 DOI: 10.1128/mmbr.64.4.821-846.2000] [Cited by in Crossref: 479] [Cited by in F6Publishing: 427] [Article Influence: 22.8] [Reference Citation Analysis]
280 K�hn K, Lotz M. Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes. Arthritis & Rheumatism 2001;44:1644-53. [DOI: 10.1002/1529-0131(200107)44:7<1644::aid-art287>3.0.co;2-s] [Cited by in Crossref: 44] [Cited by in F6Publishing: 47] [Article Influence: 2.1] [Reference Citation Analysis]
281 Svingen PA, Karp JE, Krajewski S, Mesner PW, Gore SD, Burke PJ, Reed JC, Lazebnik YA, Kaufmann SH. Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood 2000;96:3922-31. [DOI: 10.1182/blood.v96.12.3922] [Cited by in Crossref: 37] [Cited by in F6Publishing: 25] [Article Influence: 1.7] [Reference Citation Analysis]
282 Svingen PA, Karp JE, Krajewski S, Mesner PW, Gore SD, Burke PJ, Reed JC, Lazebnik YA, Kaufmann SH. Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood 2000;96:3922-31. [DOI: 10.1182/blood.v96.12.3922.h8003922_3922_3931] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.1] [Reference Citation Analysis]
283 Kim IK, Chung CW, Woo HN, Hong GS, Nagata S, Jung YK. Reconstitution of caspase-8 sensitizes JB6 cells to TRAIL. Biochem Biophys Res Commun. 2000;277:311-316. [PMID: 11032723 DOI: 10.1006/bbrc.2000.3673] [Cited by in Crossref: 13] [Cited by in F6Publishing: 15] [Article Influence: 0.6] [Reference Citation Analysis]
284 Angell JE, Lindner DJ, Shapiro PS, Hofmann ER, Kalvakolanu DV. Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach. J Biol Chem. 2000;275:33416-33426. [PMID: 10924506 DOI: 10.1074/jbc.M003929200] [Cited by in Crossref: 159] [Cited by in F6Publishing: 151] [Article Influence: 7.2] [Reference Citation Analysis]
285 Datta R, Oki E, Endo K, Biedermann V, Ren J, Kufe D. XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage. J Biol Chem 2000;275:31733-8. [PMID: 10930419 DOI: 10.1074/jbc.M910231199] [Cited by in Crossref: 66] [Cited by in F6Publishing: 60] [Article Influence: 3.0] [Reference Citation Analysis]
286 Ritchie H, Fragoyannis A. Thrombin inhibits apoptosis of monocytes and plasminogen activator inhibitor 2 (PAI-2) is not responsible for this inhibition. Exp Cell Res 2000;260:20-9. [PMID: 11010807 DOI: 10.1006/excr.2000.4957] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 0.6] [Reference Citation Analysis]
287 Hengartner MO. The biochemistry of apoptosis. Nature. 2000;407:770-776. [PMID: 11048727 DOI: 10.1038/35037710] [Cited by in Crossref: 4935] [Cited by in F6Publishing: 4654] [Article Influence: 224.3] [Reference Citation Analysis]
288 Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol. 2000;2:469-475. [PMID: 10934466 DOI: 10.1038/35019501] [Cited by in Crossref: 1046] [Cited by in F6Publishing: 985] [Article Influence: 47.5] [Reference Citation Analysis]
289 Gottlieb RA. Mitochondria: execution central. FEBS Letters 2000;482:6-12. [DOI: 10.1016/s0014-5793(00)02010-x] [Cited by in Crossref: 127] [Cited by in F6Publishing: 122] [Article Influence: 5.8] [Reference Citation Analysis]
290 Talanian RV, Brady KD, Cryns VL. Caspases as Targets for Anti-Inflammatory and Anti-Apoptotic Drug Discovery. J Med Chem 2000;43:3351-71. [DOI: 10.1021/jm000060f] [Cited by in Crossref: 79] [Cited by in F6Publishing: 80] [Article Influence: 3.6] [Reference Citation Analysis]
291 Zhuang S, Simon G. Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells. American Journal of Physiology-Cell Physiology 2000;279:C341-51. [DOI: 10.1152/ajpcell.2000.279.2.c341] [Cited by in Crossref: 71] [Cited by in F6Publishing: 68] [Article Influence: 3.2] [Reference Citation Analysis]
292 Babél LM, Linneversl CJ, Schmidt BF. Production of Active Mammalian and Viral Proteases in Bacterial Expression Systems. Biotechnology and Genetic Engineering Reviews 2000;17:213-54. [DOI: 10.1080/02648725.2000.10647993] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.1] [Reference Citation Analysis]
293 Saunders PA, Cooper JA, Roodell MM, Schroeder DA, Borchert CJ, Isaacson AL, Schendel MJ, Godfrey KG, Cahill DR, Walz AM, Loegering RT, Gaylord H, Woyno IJ, Kaluyzhny AE, Krzyzek RA, Mortari F, Tsang M, Roff CF. Quantification of Active Caspase 3 in Apoptotic Cells. Analytical Biochemistry 2000;284:114-24. [DOI: 10.1006/abio.2000.4690] [Cited by in Crossref: 31] [Cited by in F6Publishing: 31] [Article Influence: 1.4] [Reference Citation Analysis]
294 Hotti A, Järvinen K, Siivola P, Hölttä E. Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases. Oncogene. 2000;19:2354-2362. [PMID: 10822387 DOI: 10.1038/sj.onc.1203567] [Cited by in Crossref: 48] [Cited by in F6Publishing: 48] [Article Influence: 2.2] [Reference Citation Analysis]
295 Hermisson M, Wagenknecht B, Wolburg H, Glaser T, Dichgans J, Weller M. Sensitization to CD95 ligand-induced apoptosis in human glioma cells by hyperthermia involves enhanced cytochrome c release. Oncogene. 2000;19:2338-2345. [PMID: 10822385 DOI: 10.1038/sj.onc.1203554] [Cited by in Crossref: 26] [Cited by in F6Publishing: 26] [Article Influence: 1.2] [Reference Citation Analysis]
296 Kang SJ, Wang S, Hara H, Peterson EP, Namura S, Amin-Hanjani S, Huang Z, Srinivasan A, Tomaselli KJ, Thornberry NA, Moskowitz MA, Yuan J. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol 2000;149:613-22. [PMID: 10791975 DOI: 10.1083/jcb.149.3.613] [Cited by in Crossref: 233] [Cited by in F6Publishing: 227] [Article Influence: 10.6] [Reference Citation Analysis]
297 Pandey P, Farber R, Nakazawa A, Kumar S, Bharti A, Nalin C, Weichselbaum R, Kufe D, Kharbanda S. Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene 2000;19:1975-81. [PMID: 10803458 DOI: 10.1038/sj.onc.1203531] [Cited by in Crossref: 222] [Cited by in F6Publishing: 205] [Article Influence: 10.1] [Reference Citation Analysis]
298 Stennicke HR, Salvesen GS. Caspases - controlling intracellular signals by protease zymogen activation. Biochim Biophys Acta 2000;1477:299-306. [PMID: 10708865 DOI: 10.1016/s0167-4838(99)00281-2] [Cited by in Crossref: 215] [Cited by in F6Publishing: 205] [Article Influence: 9.8] [Reference Citation Analysis]
299 Kaufmann SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res. 2000;256:42-49. [PMID: 10739650 DOI: 10.1006/excr.2000.4838] [Cited by in Crossref: 780] [Cited by in F6Publishing: 755] [Article Influence: 35.5] [Reference Citation Analysis]
300 Ritter PM, Marti A, Blanc C, Baltzer A, Krajewski S, Reed JC, Jaggi R. Nuclear localization of procaspase-9 and processing by a caspase-3-like activity in mammary epithelial cells. European Journal of Cell Biology 2000;79:358-64. [DOI: 10.1078/s0171-9335(04)70040-0] [Cited by in Crossref: 31] [Cited by in F6Publishing: 33] [Article Influence: 1.4] [Reference Citation Analysis]
301 Grullich C, Sullards MC, Fuks Z, Merrill AH Jr, Kolesnick R. CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis. J Biol Chem 2000;275:8650-6. [PMID: 10722705 DOI: 10.1074/jbc.275.12.8650] [Cited by in Crossref: 69] [Cited by in F6Publishing: 65] [Article Influence: 3.1] [Reference Citation Analysis]
302 Bratton SB, Macfarlane M, Cain K, Cohen GM. Protein Complexes Activate Distinct Caspase Cascades in Death Receptor and Stress-Induced Apoptosis. Experimental Cell Research 2000;256:27-33. [DOI: 10.1006/excr.2000.4835] [Cited by in Crossref: 223] [Cited by in F6Publishing: 207] [Article Influence: 10.1] [Reference Citation Analysis]
303 Huang Q, Deveraux QL, Maeda S, Salvesen GS, Stennicke HR, Hammock BD, Reed JC. Evolutionary conservation of apoptosis mechanisms: lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9. Proc Natl Acad Sci U S A 2000;97:1427-32. [PMID: 10677478 DOI: 10.1073/pnas.97.4.1427] [Cited by in Crossref: 91] [Cited by in F6Publishing: 86] [Article Influence: 4.1] [Reference Citation Analysis]
304 Chua BT, Guo K, Li P. Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases. J Biol Chem 2000;275:5131-5. [PMID: 10671558 DOI: 10.1074/jbc.275.7.5131] [Cited by in Crossref: 222] [Cited by in F6Publishing: 207] [Article Influence: 10.1] [Reference Citation Analysis]
305 Mirkes PE, Little SA. Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine. Toxicol Appl Pharmacol 2000;162:197-206. [PMID: 10652248 DOI: 10.1006/taap.1999.8849] [Cited by in Crossref: 49] [Cited by in F6Publishing: 42] [Article Influence: 2.2] [Reference Citation Analysis]
306 Fiers W, Beyaert R, Declercq W, Vandenabeele P. More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene. 1999;18:7719-7730. [PMID: 10618712 DOI: 10.1038/sj.onc.1203249] [Cited by in Crossref: 606] [Cited by in F6Publishing: 583] [Article Influence: 27.5] [Reference Citation Analysis]
307 Waterhouse NJ, Green DR. Mitochondria and apoptosis: HQ or high-security prison? J Clin Immunol 1999;19:378-87. [PMID: 10634211 DOI: 10.1023/a:1020550716138] [Cited by in Crossref: 39] [Cited by in F6Publishing: 37] [Article Influence: 1.8] [Reference Citation Analysis]
308 Rodriguez J, Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev 1999;13:3179-84. [PMID: 10617566 DOI: 10.1101/gad.13.24.3179] [Cited by in Crossref: 385] [Cited by in F6Publishing: 357] [Article Influence: 17.5] [Reference Citation Analysis]
309 Salvesen GS. Caspase 8: igniting the death machine. Structure 1999;7:R225-9. [PMID: 10545333 DOI: 10.1016/s0969-2126(00)80048-9] [Cited by in Crossref: 28] [Cited by in F6Publishing: 27] [Article Influence: 1.2] [Reference Citation Analysis]
310 Wolf BB, Schuler M, Echeverri F, Green DR. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J Biol Chem. 1999;274:30651-30656. [PMID: 10521451 DOI: 10.1074/jbc.274.43.30651] [Cited by in Crossref: 333] [Cited by in F6Publishing: 328] [Article Influence: 14.5] [Reference Citation Analysis]
311 Wiese S, Digby MR, Gunnersen JM, Götz R, Pei G, Holtmann B, Lowenthal J, Sendtner M. The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons. Nat Neurosci 1999;2:978-83. [DOI: 10.1038/14777] [Cited by in Crossref: 48] [Cited by in F6Publishing: 50] [Article Influence: 2.1] [Reference Citation Analysis]
312 Salvesen GS, Dixit VM. Caspase activation: the induced-proximity model. Proc Natl Acad Sci USA. 1999;96:10964-10967. [PMID: 10500109 DOI: 10.1073/pnas.96.20.10964] [Cited by in Crossref: 626] [Cited by in F6Publishing: 586] [Article Influence: 27.2] [Reference Citation Analysis]
313 Mesner PW Jr, Bible KC, Martins LM, Kottke TJ, Srinivasula SM, Svingen PA, Chilcote TJ, Basi GS, Tung JS, Krajewski S, Reed JC, Alnemri ES, Earnshaw WC, Kaufmann SH. Characterization of caspase processing and activation in HL-60 cell cytosol under cell-free conditions. Nucleotide requirement and inhibitor profile. J Biol Chem 1999;274:22635-45. [PMID: 10428844 DOI: 10.1074/jbc.274.32.22635] [Cited by in Crossref: 53] [Cited by in F6Publishing: 48] [Article Influence: 2.3] [Reference Citation Analysis]
314 Kelley TW, Graham MM, Doseff AI, Pomerantz RW, Lau SM, Ostrowski MC, Franke TF, Marsh CB. Macrophage Colony-stimulating Factor Promotes Cell Survival through Akt/Protein Kinase B. Journal of Biological Chemistry 1999;274:26393-8. [DOI: 10.1074/jbc.274.37.26393] [Cited by in Crossref: 120] [Cited by in F6Publishing: 119] [Article Influence: 5.2] [Reference Citation Analysis]
315 Wolf BB, Goldstein JC, Stennicke HR, Beere H, Amarante-mendes GP, Salvesen GS, Green DR. Calpain Functions in a Caspase-Independent Manner to Promote Apoptosis-Like Events During Platelet Activation. Blood 1999;94:1683-92. [DOI: 10.1182/blood.v94.5.1683.417k37_1683_1692] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 0.6] [Reference Citation Analysis]
316 Wolf BB, Goldstein JC, Stennicke HR, Beere H, Amarante-mendes GP, Salvesen GS, Green DR. Calpain Functions in a Caspase-Independent Manner to Promote Apoptosis-Like Events During Platelet Activation. Blood 1999;94:1683-92. [DOI: 10.1182/blood.v94.5.1683] [Cited by in Crossref: 229] [Cited by in F6Publishing: 173] [Article Influence: 10.0] [Reference Citation Analysis]
317 Wolf BB, Green DR. Suicidal tendencies: apoptotic cell death by caspase family proteinases. J Biol Chem. 1999;274:20049-20052. [PMID: 10400609 DOI: 10.1074/jbc.274.29.20049] [Cited by in Crossref: 639] [Cited by in F6Publishing: 622] [Article Influence: 27.8] [Reference Citation Analysis]
318 Saleh A, Srinivasula SM, Acharya S, Fishel R, Alnemri ES. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem 1999;274:17941-5. [PMID: 10364241 DOI: 10.1074/jbc.274.25.17941] [Cited by in Crossref: 342] [Cited by in F6Publishing: 323] [Article Influence: 14.9] [Reference Citation Analysis]
319 Yuan J, Yankner BA. Caspase activity sows the seeds of neuronal death. Nat Cell Biol 1999;1:E44-5. [DOI: 10.1038/10037] [Cited by in Crossref: 32] [Cited by in F6Publishing: 28] [Article Influence: 1.4] [Reference Citation Analysis]