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For: Jaeschke A, Rincón M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci USA. 2005;102:6931-6935. [PMID: 15867147 DOI: 10.1073/pnas.0502143102] [Cited by in Crossref: 64] [Cited by in F6Publishing: 61] [Article Influence: 3.8] [Reference Citation Analysis]
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10 Abdelli S, Bonny C. JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: functional consequences for insulin signaling. PLoS One 2012;7:e35997. [PMID: 22563476 DOI: 10.1371/journal.pone.0035997] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 2.0] [Reference Citation Analysis]
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15 Choi Y, Hur CG, Park T. Induction of olfaction and cancer-related genes in mice fed a high-fat diet as assessed through the mode-of-action by network identification analysis. PLoS One 2013;8:e56610. [PMID: 23555558 DOI: 10.1371/journal.pone.0056610] [Cited by in Crossref: 15] [Cited by in F6Publishing: 11] [Article Influence: 1.7] [Reference Citation Analysis]
16 Ijaz A, Tejada T, Catanuto P, Xia X, Elliot SJ, Lenz O, Jauregui A, Saenz MO, Molano RD, Pileggi A, Ricordi C, Fornoni A. Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes. Kidney Int 2009;75:381-8. [PMID: 18971923 DOI: 10.1038/ki.2008.559] [Cited by in Crossref: 48] [Cited by in F6Publishing: 42] [Article Influence: 3.4] [Reference Citation Analysis]
17 Yang L, Huang P, Li F, Zhao L, Zhang Y, Li S, Gan Z, Lin A, Li W, Liu Y. c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells. PLoS One 2012;7:e48611. [PMID: 23139803 DOI: 10.1371/journal.pone.0048611] [Cited by in Crossref: 16] [Cited by in F6Publishing: 18] [Article Influence: 1.6] [Reference Citation Analysis]
18 Santos Júnior RR, Sartori A, Bonato VL, Coelho Castelo AA, Vilella CA, Zollner RL, Silva CL. Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression. Clin Exp Immunol 2007;149:570-8. [PMID: 17590177 DOI: 10.1111/j.1365-2249.2007.03433.x] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 1.5] [Reference Citation Analysis]
19 Zhao M, Zhang Y, Liu Y, Sun G, Tian H, Hong L. Polymorphisms in MAPK9 (rs4147385) and CSF1R (rs17725712) are associated with the development of inhibitors in patients with haemophilia A in North China. Int J Lab Hematol 2019;41:572-7. [PMID: 31149782 DOI: 10.1111/ijlh.13055] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
20 Kassouf T, Sumara G. Impact of Conventional and Atypical MAPKs on the Development of Metabolic Diseases. Biomolecules 2020;10:E1256. [PMID: 32872540 DOI: 10.3390/biom10091256] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 2.5] [Reference Citation Analysis]
21 Ebelt ND, Cantrell MA, Van Den Berg CL. c-Jun N-Terminal Kinases Mediate a Wide Range of Targets in the Metastatic Cascade. Genes Cancer 2013;4:378-87. [PMID: 24349635 DOI: 10.1177/1947601913485413] [Cited by in Crossref: 43] [Cited by in F6Publishing: 43] [Article Influence: 5.4] [Reference Citation Analysis]
22 Stanley WJ, Trivedi PM, Sutherland AP, Thomas HE, Gurzov EN. Differential regulation of pro-inflammatory cytokine signalling by protein tyrosine phosphatases in pancreatic β-cells. Journal of Molecular Endocrinology 2017;59:325-37. [DOI: 10.1530/jme-17-0089] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
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24 Seriani R, Junqueira Mde S, de Toledo AC, Martins MA, Seckler M, Alencar AM, Negri EM, Silva LF, Mauad T, Saldiva PH, Macchione M. Diesel exhaust particulates affect cell signaling, mucin profiles, and apoptosis in trachea explants of Balb/C mice. Environ Toxicol 2015;30:1297-308. [PMID: 24777914 DOI: 10.1002/tox.22000] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.8] [Reference Citation Analysis]
25 Winchester CL, Ohzeki H, Vouyiouklis DA, Thompson R, Penninger JM, Yamagami K, Norrie JD, Hunter R, Pratt JA, Morris BJ. Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia. Human Molecular Genetics 2012;21:4910-21. [DOI: 10.1093/hmg/dds331] [Cited by in Crossref: 33] [Cited by in F6Publishing: 33] [Article Influence: 3.3] [Reference Citation Analysis]
26 Manieri E, Sabio G. Stress kinases in the modulation of metabolism and energy balance. J Mol Endocrinol 2015;55:R11-22. [PMID: 26363062 DOI: 10.1530/JME-15-0146] [Cited by in Crossref: 42] [Cited by in F6Publishing: 26] [Article Influence: 7.0] [Reference Citation Analysis]
27 Gehi BR, Gadhave K, Uversky VN, Giri R. Intrinsic disorder in proteins associated with oxidative stress-induced JNK signaling. Cell Mol Life Sci 2022;79:202. [PMID: 35325330 DOI: 10.1007/s00018-022-04230-4] [Reference Citation Analysis]
28 Wang Y, Singh R, Lefkowitch JH, Rigoli RM, Czaja MJ. Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway. J Biol Chem. 2006;281:15258-15267. [PMID: 16571730 DOI: 10.1074/jbc.m512953200] [Cited by in Crossref: 167] [Cited by in F6Publishing: 87] [Article Influence: 10.4] [Reference Citation Analysis]
29 Zhang W, Liang F, Li Q, Sun H, Li F, Jiao Z, Lei J. LncRNA MIR205HG accelerates cell proliferation, migration and invasion in hepatoblastoma through the activation of MAPK signaling pathway and PI3K/AKT signaling pathway. Biol Direct 2022;17:2. [PMID: 34996511 DOI: 10.1186/s13062-021-00309-3] [Reference Citation Analysis]
30 Shaw D, Wang SM, Villaseñor AG, Tsing S, Walter D, Browner MF, Barnett J, Kuglstatter A. The Crystal Structure of JNK2 Reveals Conformational Flexibility in the MAP Kinase Insert and Indicates Its Involvement in the Regulation of Catalytic Activity. Journal of Molecular Biology 2008;383:885-93. [DOI: 10.1016/j.jmb.2008.08.086] [Cited by in Crossref: 40] [Cited by in F6Publishing: 40] [Article Influence: 2.9] [Reference Citation Analysis]
31 Lim W, Gee K, Mishra S, Kumar A. Regulation of B7.1 costimulatory molecule is mediated by the IFN regulatory factor-7 through the activation of JNK in lipopolysaccharide-stimulated human monocytic cells. J Immunol 2005;175:5690-700. [PMID: 16237059 DOI: 10.4049/jimmunol.175.9.5690] [Cited by in Crossref: 29] [Cited by in F6Publishing: 32] [Article Influence: 1.7] [Reference Citation Analysis]
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33 Rincón M, Davis RJ. Regulation of the immune response by stress-activated protein kinases. Immunol Rev. 2009;228:212-224. [PMID: 19290930 DOI: 10.1111/j.1600-065x.2008.00744.x] [Cited by in Crossref: 181] [Cited by in F6Publishing: 106] [Article Influence: 13.9] [Reference Citation Analysis]
34 Jeffrey KL, Camps M, Rommel C, Mackay CR. Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov 2007;6:391-403. [PMID: 17473844 DOI: 10.1038/nrd2289] [Cited by in Crossref: 308] [Cited by in F6Publishing: 293] [Article Influence: 20.5] [Reference Citation Analysis]
35 Osto E, Cosentino F. The Role of Oxidative Stress in Endothelial Dysfunction and Vascular Inflammation. Nitric Oxide. Elsevier; 2010. pp. 705-54. [DOI: 10.1016/b978-0-12-373866-0.00022-8] [Cited by in Crossref: 7] [Article Influence: 0.6] [Reference Citation Analysis]
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37 Gunawan BK, Liu ZX, Han D, Hanawa N, Gaarde WA, Kaplowitz N. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. Gastroenterology. 2006;131:165-178. [PMID: 16831600 DOI: 10.1053/j.gastro.2006.03.045] [Cited by in Crossref: 320] [Cited by in F6Publishing: 304] [Article Influence: 20.0] [Reference Citation Analysis]
38 Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci U S A 2006;103:10741-6. [PMID: 16818881 DOI: 10.1073/pnas.0603509103] [Cited by in Crossref: 252] [Cited by in F6Publishing: 233] [Article Influence: 15.8] [Reference Citation Analysis]
39 Bogoyevitch MA, Arthur PG. Inhibitors of c-Jun N-terminal kinases: JuNK no more? Biochim Biophys Acta 2008;1784:76-93. [PMID: 17964301 DOI: 10.1016/j.bbapap.2007.09.013] [Cited by in Crossref: 90] [Cited by in F6Publishing: 95] [Article Influence: 6.0] [Reference Citation Analysis]
40 Satoh T, Abiru N, Kobayashi M, Zhou H, Nakamura K, Kuriya G, Nakamura H, Nagayama Y, Kawasaki E, Yamasaki H, Yu L, Eisenbarth GS, Araki E, Mori M, Oyadomari S, Eguchi K. CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse. Apoptosis 2011;16:438-48. [DOI: 10.1007/s10495-011-0576-2] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 1.4] [Reference Citation Analysis]
41 Novoselova EG, Glushkova OV, Lunin SM, Khrenov MO, Parfenyuk SB, Novoselova TV, Sharapov MG, Gordeeva AE, Novoselov VI, Fesenko EE. Thymulin and peroxiredoxin 6 have protective effects against streptozotocin-induced type 1 diabetes in mice. Int J Immunopathol Pharmacol 2021;35:20587384211005645. [PMID: 33779346 DOI: 10.1177/20587384211005645] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
42 Xie XL, Zhou WT, Zhang KK, Yuan Y, Qiu EM, Shen YW, Wang Q. PCB52 induces hepatotoxicity in male offspring through aggravating loss of clearance capacity and activating the apoptosis: Sex-biased effects on rats. Chemosphere 2019;227:389-400. [PMID: 31003123 DOI: 10.1016/j.chemosphere.2019.04.077] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
43 Osto E, Matter CM, Kouroedov A, Malinski T, Bachschmid M, Camici GG, Kilic U, Stallmach T, Boren J, Iliceto S, Lüscher TF, Cosentino F. c-Jun N-Terminal Kinase 2 Deficiency Protects Against Hypercholesterolemia-Induced Endothelial Dysfunction and Oxidative Stress. Circulation 2008;118:2073-80. [DOI: 10.1161/circulationaha.108.765032] [Cited by in Crossref: 68] [Cited by in F6Publishing: 36] [Article Influence: 4.9] [Reference Citation Analysis]
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45 Koch P, Gehringer M, Laufer SA. Inhibitors of c-Jun N-terminal kinases: an update. J Med Chem 2015;58:72-95. [PMID: 25415535 DOI: 10.1021/jm501212r] [Cited by in Crossref: 56] [Cited by in F6Publishing: 51] [Article Influence: 7.0] [Reference Citation Analysis]
46 Temkin V, Karin M. From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey. Immunol Rev 2007;220:8-21. [DOI: 10.1111/j.1600-065x.2007.00560.x] [Cited by in Crossref: 82] [Cited by in F6Publishing: 34] [Article Influence: 5.5] [Reference Citation Analysis]
47 Tran EH, Azuma YT, Chen M, Weston C, Davis RJ, Flavell RA. Inactivation of JNK1 enhances innate IL-10 production and dampens autoimmune inflammation in the brain. Proc Natl Acad Sci U S A 2006;103:13451-6. [PMID: 16938889 DOI: 10.1073/pnas.0601155103] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 1.9] [Reference Citation Analysis]
48 Nikolic I, Leiva M, Sabio G. The role of stress kinases in metabolic disease. Nat Rev Endocrinol 2020;16:697-716. [PMID: 33067545 DOI: 10.1038/s41574-020-00418-5] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 5.5] [Reference Citation Analysis]
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50 Astermark J, Donfield SM, Gomperts ED, Schwarz J, Menius ED, Pavlova A, Oldenburg J, Kessing B, DiMichele DM, Shapiro AD, Winkler CA, Berntorp E; Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort. The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort. Blood 2013;121:1446-54. [PMID: 23223434 DOI: 10.1182/blood-2012-06-434803] [Cited by in Crossref: 72] [Cited by in F6Publishing: 59] [Article Influence: 7.2] [Reference Citation Analysis]
51 Tarantino G, Caputi A. JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease. World J Gastroenterol 2011; 17(33): 3785-3794 [PMID: 21987620 DOI: 10.3748/wjg.v17.i33.3785] [Cited by in CrossRef: 82] [Cited by in F6Publishing: 80] [Article Influence: 7.5] [Reference Citation Analysis]
52 Chen J, Teng D, Wu Z, Li W, Feng Y, Tang Y, Liu G. Insights into the Molecular Mechanisms of Liuwei Dihuang Decoction via Network Pharmacology. Chem Res Toxicol 2021;34:91-102. [PMID: 33332098 DOI: 10.1021/acs.chemrestox.0c00359] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
53 Kaneto H, Katakami N, Kawamori D, Miyatsuka T, Sakamoto K, Matsuoka TA, Matsuhisa M, Yamasaki Y. Involvement of oxidative stress in the pathogenesis of diabetes. Antioxid Redox Signal. 2007;9:355-366. [PMID: 17184181 DOI: 10.1089/ars.2006.1465] [Cited by in Crossref: 159] [Cited by in F6Publishing: 146] [Article Influence: 10.6] [Reference Citation Analysis]
54 Larsen CM, Døssing MG, Papa S, Franzoso G, Billestrup N, Mandrup-Poulsen T. Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells. Diabetologia 2006;49:980-9. [PMID: 16528573 DOI: 10.1007/s00125-006-0164-0] [Cited by in Crossref: 25] [Cited by in F6Publishing: 23] [Article Influence: 1.6] [Reference Citation Analysis]
55 Leibowitz G, Cerasi E, Ketzinel-Gilad M. The role of mTOR in the adaptation and failure of beta-cells in type 2 diabetes. Diabetes Obes Metab 2008;10 Suppl 4:157-69. [PMID: 18834443 DOI: 10.1111/j.1463-1326.2008.00952.x] [Cited by in Crossref: 45] [Cited by in F6Publishing: 45] [Article Influence: 3.2] [Reference Citation Analysis]
56 Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling. Diabetes 2008;57:3034-44. [PMID: 18591394 DOI: 10.2337/db07-1802] [Cited by in Crossref: 103] [Cited by in F6Publishing: 101] [Article Influence: 7.4] [Reference Citation Analysis]
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58 Rozo AV, Vijayvargia R, Weiss HR, Ruan H. Silencing Jnk1 and Jnk2 accelerates basal lipolysis and promotes fatty acid re-esterification in mouse adipocytes. Diabetologia 2008;51:1493-504. [PMID: 18528680 DOI: 10.1007/s00125-008-1036-6] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 1.2] [Reference Citation Analysis]
59 Yang TY, Yen CC, Lee KI, Su CC, Yang CY, Wu CC, Hsieh SS, Ueng KC, Huang CF. Molybdenum induces pancreatic β-cell dysfunction and apoptosis via interdependent of JNK and AMPK activation-regulated mitochondria-dependent and ER stress-triggered pathways. Toxicol Appl Pharmacol 2016;294:54-64. [PMID: 26806093 DOI: 10.1016/j.taap.2016.01.013] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.5] [Reference Citation Analysis]
60 Graczyk PP. JNK inhibitors as anti-inflammatory and neuroprotective agents. Future Med Chem 2013;5:539-51. [PMID: 23573972 DOI: 10.4155/fmc.13.34] [Cited by in Crossref: 26] [Cited by in F6Publishing: 24] [Article Influence: 2.9] [Reference Citation Analysis]
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