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For: Liedtke C, Bangen JM, Freimuth J, Beraza N, Lambertz D, Cubero FJ, Hatting M, Karlmark KR, Streetz KL, Krombach GA. Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury. Gastroenterology. 2011;141:2176-2187. [PMID: 21878202 DOI: 10.1053/j.gastro.2011.08.037] [Cited by in Crossref: 89] [Cited by in F6Publishing: 76] [Article Influence: 8.9] [Reference Citation Analysis]
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8 Afonso MB, Rodrigues PM, Simão AL, Ofengeim D, Carvalho T, Amaral JD, Gaspar MM, Cortez-Pinto H, Castro RE, Yuan J, Rodrigues CM. Activation of necroptosis in human and experimental cholestasis. Cell Death Dis 2016;7:e2390. [PMID: 27685634 DOI: 10.1038/cddis.2016.280] [Cited by in Crossref: 64] [Cited by in F6Publishing: 57] [Article Influence: 12.8] [Reference Citation Analysis]
9 Huang D, Zheng X, Wang ZA, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J. The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process. Mol Cell Biol 2017;37:e00497-16. [PMID: 27920255 DOI: 10.1128/MCB.00497-16] [Cited by in Crossref: 53] [Cited by in F6Publishing: 38] [Article Influence: 13.3] [Reference Citation Analysis]
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12 Liao L, Schneider KM, Galvez EJC, Frissen M, Marschall HU, Su H, Hatting M, Wahlström A, Haybaeck J, Puchas P, Mohs A, Peng J, Bergheim I, Nier A, Hennings J, Reißing J, Zimmermann HW, Longerich T, Strowig T, Liedtke C, Cubero FJ, Trautwein C. Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis. Gut 2019;68:1477-92. [PMID: 30872395 DOI: 10.1136/gutjnl-2018-316670] [Cited by in Crossref: 38] [Cited by in F6Publishing: 30] [Article Influence: 19.0] [Reference Citation Analysis]
13 Kaemmerer E, Kuhn P, Schneider U, Jeon MK, Klaus C, Schiffer M, Weisner D, Liedtke C, Jäkel J, Kennes LN, Hilgers RD, Wagner N, Gassler N. Intestinal genetic inactivation of caspase-8 diminishes migration of enterocytes. World J Gastroenterol 2015;21:4499-508. [PMID: 25914458 DOI: 10.3748/wjg.v21.i15.4499] [Cited by in CrossRef: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
14 Hatting M, Zhao G, Schumacher F, Sellge G, Al Masaoudi M, Gaβler N, Boekschoten M, Müller M, Liedtke C, Cubero FJ. Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents. Hepatology. 2013;57:2189-2201. [PMID: 23339067 DOI: 10.1002/hep.26271] [Cited by in Crossref: 64] [Cited by in F6Publishing: 62] [Article Influence: 8.0] [Reference Citation Analysis]
15 Jun-Long H, Yi L, Bao-Lian Z, Jia-Si L, Ning Z, Zhou-Heng Y, Xue-Jun S, Wen-Wu L. Necroptosis Signaling Pathways in Stroke: From Mechanisms to Therapies. Curr Neuropharmacol 2018;16:1327-39. [PMID: 29663889 DOI: 10.2174/1570159X16666180416152243] [Cited by in Crossref: 15] [Cited by in F6Publishing: 7] [Article Influence: 5.0] [Reference Citation Analysis]
16 Huber Y, Gehrke N, Biedenbach J, Helmig S, Simon P, Straub BK, Bergheim I, Huber T, Schuppan D, Galle PR, Wörns MA, Schuchmann M, Schattenberg JM. Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu. Cell Death Dis 2017;8:e2893. [PMID: 28640248 DOI: 10.1038/cddis.2017.266] [Cited by in Crossref: 10] [Cited by in F6Publishing: 7] [Article Influence: 2.5] [Reference Citation Analysis]
17 Jouan-Lanhouet S, Riquet F, Duprez L, Vanden Berghe T, Takahashi N, Vandenabeele P. Necroptosis, in vivo detection in experimental disease models. Semin Cell Dev Biol 2014;35:2-13. [PMID: 25160988 DOI: 10.1016/j.semcdb.2014.08.010] [Cited by in Crossref: 99] [Cited by in F6Publishing: 92] [Article Influence: 14.1] [Reference Citation Analysis]
18 Shalini S, Dorstyn L, Dawar S, Kumar S. Old, new and emerging functions of caspases. Cell Death Differ 2015;22:526-39. [PMID: 25526085 DOI: 10.1038/cdd.2014.216] [Cited by in Crossref: 589] [Cited by in F6Publishing: 468] [Article Influence: 84.1] [Reference Citation Analysis]
19 Hirsova P, Gores GJ. Reply. Cell Mol Gastroenterol Hepatol 2015;1:265-6. [PMID: 28210680 DOI: 10.1016/j.jcmgh.2015.03.001] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
20 Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S. Synchronized renal tubular cell death involves ferroptosis. Proc Natl Acad Sci U S A 2014;111:16836-41. [PMID: 25385600 DOI: 10.1073/pnas.1415518111] [Cited by in Crossref: 411] [Cited by in F6Publishing: 375] [Article Influence: 58.7] [Reference Citation Analysis]
21 Carranza-Trejo AM, Vetvicka V, Vistejnova L, Kralickova M, Montufar EB. Hepatocyte and immune cell crosstalk in non-alcoholic fatty liver disease. Expert Rev Gastroenterol Hepatol 2021;15:783-96. [PMID: 33557653 DOI: 10.1080/17474124.2021.1887730] [Reference Citation Analysis]
22 Fernández-Álvarez S, Gutiérrez-de Juan V, Zubiete-Franco I, Barbier-Torres L, Lahoz A, Parés A, Luka Z, Wagner C, Lu SC, Mato JM. TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency. Lab Invest. 2015;95:223-236. [PMID: 25531568 DOI: 10.1038/labinvest.2014.151] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 2.3] [Reference Citation Analysis]
23 Freimuth J, Bangen JM, Lambertz D, Hu W, Nevzorova YA, Sonntag R, Gassler N, Riethmacher D, Trautwein C, Liedtke C. Loss of caspase-8 in hepatocytes accelerates the onset of liver regeneration in mice through premature nuclear factor kappa B activation. Hepatology 2013;58:1779-89. [PMID: 23728913 DOI: 10.1002/hep.26538] [Cited by in Crossref: 22] [Cited by in F6Publishing: 15] [Article Influence: 2.8] [Reference Citation Analysis]
24 Sahin H, Borkham-Kamphorst E, do O NT, Berres ML, Kaldenbach M, Schmitz P, Weiskirchen R, Liedtke C, Streetz KL, Maedler K, Trautwein C, Wasmuth HE. Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes. Hepatology 2013;57:797-805. [PMID: 22996399 DOI: 10.1002/hep.26069] [Cited by in Crossref: 39] [Cited by in F6Publishing: 37] [Article Influence: 4.9] [Reference Citation Analysis]
25 Kang YJ, Bang BR, Han KH, Hong L, Shim EJ, Ma J, Lerner RA, Otsuka M. Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling. Nat Commun 2015;6:8371. [PMID: 26381214 DOI: 10.1038/ncomms9371] [Cited by in Crossref: 56] [Cited by in F6Publishing: 59] [Article Influence: 9.3] [Reference Citation Analysis]
26 Wang K. Molecular mechanisms of liver injury: apoptosis or necrosis. Exp Toxicol Pathol. 2014;66:351-356. [PMID: 24867271 DOI: 10.1016/j.etp.2014.04.004] [Cited by in Crossref: 44] [Cited by in F6Publishing: 36] [Article Influence: 6.3] [Reference Citation Analysis]
27 Ucker DS, Levine JS. Exploitation of Apoptotic Regulation in Cancer. Front Immunol 2018;9:241. [PMID: 29535707 DOI: 10.3389/fimmu.2018.00241] [Cited by in Crossref: 20] [Cited by in F6Publishing: 16] [Article Influence: 6.7] [Reference Citation Analysis]
28 Arshad MI, Piquet-Pellorce C, Filliol A, L'Helgoualc'h A, Lucas-Clerc C, Jouan-Lanhouet S, Dimanche-Boitrel MT, Samson M. The chemical inhibitors of cellular death, PJ34 and Necrostatin-1, down-regulate IL-33 expression in liver. J Mol Med (Berl) 2015;93:867-78. [PMID: 25747661 DOI: 10.1007/s00109-015-1270-6] [Cited by in Crossref: 22] [Cited by in F6Publishing: 24] [Article Influence: 3.7] [Reference Citation Analysis]
29 Soliman B, Salem A, Ghazy M, Abu-Shahba N, El Hefnawi M. Bioinformatics functional analysis of let-7a, miR-34a, and miR-199a/b reveals novel insights into immune system pathways and cancer hallmarks for hepatocellular carcinoma. Tumour Biol 2018;40:1010428318773675. [PMID: 29775159 DOI: 10.1177/1010428318773675] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
30 Kuttkat N, Mohs A, Ohl K, Hooiveld G, Longerich T, Tenbrock K, Cubero FJ, Trautwein C. Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease. Gut 2017;66:908-19. [PMID: 27686093 DOI: 10.1136/gutjnl-2015-311119] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
31 Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J. Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. J Biol Chem 2013;288:16247-61. [PMID: 23612963 DOI: 10.1074/jbc.M112.435545] [Cited by in Crossref: 155] [Cited by in F6Publishing: 89] [Article Influence: 19.4] [Reference Citation Analysis]
32 Orning P, Lien E. Multiple roles of caspase-8 in cell death, inflammation, and innate immunity. J Leukoc Biol 2021;109:121-41. [PMID: 32531842 DOI: 10.1002/JLB.3MR0420-305R] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 6.0] [Reference Citation Analysis]
33 Ehlken H, Krishna-Subramanian S, Ochoa-Callejero L, Kondylis V, Nadi NE, Straub BK, Schirmacher P, Walczak H, Kollias G, Pasparakis M. Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout. Cell Death Differ 2014;21:1721-32. [PMID: 24971483 DOI: 10.1038/cdd.2014.83] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 3.3] [Reference Citation Analysis]
34 Yang YM, Seki E. TNFα in liver fibrosis. Curr Pathobiol Rep 2015;3:253-61. [PMID: 26726307 DOI: 10.1007/s40139-015-0093-z] [Cited by in Crossref: 58] [Cited by in F6Publishing: 46] [Article Influence: 9.7] [Reference Citation Analysis]
35 Zhou Z, Han V, Han J. New components of the necroptotic pathway. Protein Cell. 2012;3:811-817. [PMID: 23073834 DOI: 10.1007/s13238-012-2083-9] [Cited by in Crossref: 52] [Cited by in F6Publishing: 47] [Article Influence: 5.8] [Reference Citation Analysis]
36 Hébert M, Jevnikar AM. The Impact of Regulated Cell Death Pathways on Alloimmune Responses and Graft Injury. Curr Transpl Rep 2015;2:242-58. [DOI: 10.1007/s40472-015-0067-4] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 0.7] [Reference Citation Analysis]
37 Afonso MB, Rodrigues PM, Carvalho T, Caridade M, Borralho P, Cortez-Pinto H, Castro RE, Rodrigues CM. Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis. Clin Sci (Lond). 2015;129:721-739. [PMID: 26201023 DOI: 10.1042/cs20140732] [Cited by in Crossref: 98] [Cited by in F6Publishing: 55] [Article Influence: 16.3] [Reference Citation Analysis]
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39 Dara L, Liu ZX, Kaplowitz N. Questions and controversies: the role of necroptosis in liver disease. Cell Death Discov 2016;2:16089. [PMID: 27924226 DOI: 10.1038/cddiscovery.2016.89] [Cited by in Crossref: 44] [Cited by in F6Publishing: 41] [Article Influence: 8.8] [Reference Citation Analysis]
40 Khan N, Lawlor KE, Murphy JM, Vince JE. More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling. Current Opinion in Immunology 2014;26:76-89. [DOI: 10.1016/j.coi.2013.10.017] [Cited by in Crossref: 56] [Cited by in F6Publishing: 48] [Article Influence: 8.0] [Reference Citation Analysis]
41 Linkermann A, Hackl MJ, Kunzendorf U, Walczak H, Krautwald S, Jevnikar AM. Necroptosis in immunity and ischemia-reperfusion injury. Am J Transplant. 2013;13:2797-2804. [PMID: 24103029 DOI: 10.1111/ajt.12448] [Cited by in Crossref: 114] [Cited by in F6Publishing: 98] [Article Influence: 14.3] [Reference Citation Analysis]
42 Chaudhary K, Liedtke C, Wertenbruch S, Trautwein C, Streetz KL. Caspase 8 differentially controls hepatocytes and non-parenchymal liver cells during chronic cholestatic liver injury in mice. Journal of Hepatology 2013;59:1292-8. [DOI: 10.1016/j.jhep.2013.07.026] [Cited by in Crossref: 10] [Cited by in F6Publishing: 6] [Article Influence: 1.3] [Reference Citation Analysis]
43 Roychowdhury S, McCullough RL, Sanz-Garcia C, Saikia P, Alkhouri N, Matloob A, Pollard KA, McMullen MR, Croniger CM, Nagy LE. Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. Hepatology. 2016;64:1518-1533. [PMID: 27301788 DOI: 10.1002/hep.28676] [Cited by in Crossref: 69] [Cited by in F6Publishing: 60] [Article Influence: 13.8] [Reference Citation Analysis]
44 Baidya R, Crawford DHG, Gautheron J, Wang H, Bridle KR. Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury. Int J Mol Sci 2020;21:E5931. [PMID: 32824744 DOI: 10.3390/ijms21165931] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
45 Cubero FJ, Peng J, Liao L, Su H, Zhao G, Zoubek ME, Macías-Rodríguez R, Ruiz-Margain A, Reißing J, Zimmermann HW, Gassler N, Luedde T, Liedtke C, Hatting M, Trautwein C. Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis. J Hepatol 2018;69:1326-34. [PMID: 30144553 DOI: 10.1016/j.jhep.2018.08.015] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
46 Tonnus W, Linkermann A. The in vivo evidence for regulated necrosis. Immunol Rev 2017;277:128-49. [PMID: 28462528 DOI: 10.1111/imr.12551] [Cited by in Crossref: 56] [Cited by in F6Publishing: 48] [Article Influence: 18.7] [Reference Citation Analysis]
47 Van TM, Polykratis A, Straub BK, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest 2017;127:2662-77. [PMID: 28628031 DOI: 10.1172/JCI92508] [Cited by in Crossref: 18] [Cited by in F6Publishing: 13] [Article Influence: 4.5] [Reference Citation Analysis]
48 Zhu Y, Cui H, Xia Y, Gan H. RIPK3-Mediated Necroptosis and Apoptosis Contributes to Renal Tubular Cell Progressive Loss and Chronic Kidney Disease Progression in Rats. PLoS One 2016;11:e0156729. [PMID: 27281190 DOI: 10.1371/journal.pone.0156729] [Cited by in Crossref: 28] [Cited by in F6Publishing: 25] [Article Influence: 5.6] [Reference Citation Analysis]
49 Engin A. Bile Acid Toxicity and Protein Kinases. Adv Exp Med Biol 2021;1275:229-58. [PMID: 33539018 DOI: 10.1007/978-3-030-49844-3_9] [Reference Citation Analysis]
50 Tayel A, Abd El Galil KH, Ebrahim MA, Ibrahim AS, El-Gayar AM, Al-Gayyar MM. Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme. Eur J Pharmacol 2014;728:151-60. [PMID: 24530413 DOI: 10.1016/j.ejphar.2014.02.001] [Cited by in Crossref: 20] [Cited by in F6Publishing: 20] [Article Influence: 2.9] [Reference Citation Analysis]
51 Cui H, Zhu Y, Jiang D. The RIP1-RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats. PLoS One 2016;11:e0150805. [PMID: 26985994 DOI: 10.1371/journal.pone.0150805] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 1.4] [Reference Citation Analysis]
52 Filliol A, Piquet-Pellorce C, Le Seyec J, Farooq M, Genet V, Lucas-Clerc C, Bertin J, Gough PJ, Dimanche-Boitrel MT, Vandenabeele P, Bertrand MJ, Samson M. RIPK1 protects from TNF-α-mediated liver damage during hepatitis. Cell Death Dis 2016;7:e2462. [PMID: 27831558 DOI: 10.1038/cddis.2016.362] [Cited by in Crossref: 42] [Cited by in F6Publishing: 40] [Article Influence: 8.4] [Reference Citation Analysis]
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54 Kondylis V, Pasparakis M. RIP Kinases in Liver Cell Death, Inflammation and Cancer. Trends Mol Med 2019;25:47-63. [PMID: 30455045 DOI: 10.1016/j.molmed.2018.10.007] [Cited by in Crossref: 30] [Cited by in F6Publishing: 23] [Article Influence: 10.0] [Reference Citation Analysis]
55 Booth L, Roberts JL, Cruickshanks N, Conley A, Durrant DE, Das A, Fisher PB, Kukreja RC, Grant S, Poklepovic A, Dent P. Phosphodiesterase 5 inhibitors enhance chemotherapy killing in gastrointestinal/genitourinary cancer cells. Mol Pharmacol 2014;85:408-19. [PMID: 24353313 DOI: 10.1124/mol.113.090043] [Cited by in Crossref: 40] [Cited by in F6Publishing: 38] [Article Influence: 5.0] [Reference Citation Analysis]
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