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For: Medina-Carmona E, Neira JL, Salido E, Fuchs JE, Palomino-Morales R, Timson DJ, Pey AL. Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism. Sci Rep 2017;7:44532. [PMID: 28291250 DOI: 10.1038/srep44532] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 4.4] [Reference Citation Analysis]
Number Citing Articles
1 Neira JL, Díaz-garcía C, Prieto M, Coutinho A. The C-terminal SAM domain of p73 binds to the N terminus of MDM2. Biochimica et Biophysica Acta (BBA) - General Subjects 2019;1863:760-70. [DOI: 10.1016/j.bbagen.2019.01.019] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 1.3] [Reference Citation Analysis]
2 Megarity CF, Abdel‐aal Bettley H, Caraher MC, Scott KA, Whitehead RC, Jowitt TA, Gutierrez A, Bryce RA, Nolan KA, Stratford IJ, Timson DJ. Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1). ChemBioChem 2019;20:2841-9. [DOI: 10.1002/cbic.201900313] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
3 Pacheco-García JL, Cano-Muñoz M, Sánchez-Ramos I, Salido E, Pey AL. Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein. J Pers Med 2020;10:E207. [PMID: 33153185 DOI: 10.3390/jpm10040207] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
4 Medina-Carmona E, Rizzuti B, Martín-Escolano R, Pacheco-García JL, Mesa-Torres N, Neira JL, Guzzi R, Pey AL. Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability. Int J Biol Macromol 2019;125:1275-88. [PMID: 30243998 DOI: 10.1016/j.ijbiomac.2018.09.108] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.8] [Reference Citation Analysis]
5 Clavería-Gimeno R, Velazquez-Campoy A, Pey AL. Thermodynamics of cooperative binding of FAD to human NQO1: Implications to understanding cofactor-dependent function and stability of the flavoproteome. Arch Biochem Biophys 2017;636:17-27. [PMID: 29100982 DOI: 10.1016/j.abb.2017.10.020] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 2.8] [Reference Citation Analysis]
6 Pey AL. Anion-specific interaction with human NQO1 inhibits flavin binding. Int J Biol Macromol 2019;126:1223-33. [PMID: 30615965 DOI: 10.1016/j.ijbiomac.2019.01.016] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 1.3] [Reference Citation Analysis]
7 Medina-carmona E, Betancor-fernández I, Santos J, Mesa-torres N, Grottelli S, Batlle C, Naganathan AN, Oppici E, Cellini B, Ventura S, Salido E, Pey AL. Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses. Human Molecular Genetics 2019;28:1-15. [DOI: 10.1093/hmg/ddy323] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 3.0] [Reference Citation Analysis]
8 Anoz-Carbonell E, Timson DJ, Pey AL, Medina M. The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity. Antioxidants (Basel) 2020;9:E772. [PMID: 32825392 DOI: 10.3390/antiox9090772] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
9 Ross D, Siegel D. The diverse functionality of NQO1 and its roles in redox control. Redox Biol 2021;41:101950. [PMID: 33774477 DOI: 10.1016/j.redox.2021.101950] [Cited by in Crossref: 6] [Cited by in F6Publishing: 10] [Article Influence: 6.0] [Reference Citation Analysis]
10 Villanueva R, Romero-Tamayo S, Laplaza R, Martínez-Olivan J, Velázquez-Campoy A, Sancho J, Ferreira P, Medina M. Redox- and Ligand Binding-Dependent Conformational Ensembles in the Human Apoptosis-Inducing Factor Regulate Its Pro-Life and Cell Death Functions. Antioxid Redox Signal 2019;30:2013-29. [PMID: 30450916 DOI: 10.1089/ars.2018.7658] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
11 Vankova P, Salido E, Timson DJ, Man P, Pey AL. A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer. Biomolecules 2019;9:E728. [PMID: 31726777 DOI: 10.3390/biom9110728] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
12 Betancor-fernández I, Timson DJ, Salido E, Pey AL. Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer. In: Ulloa-aguirre A, Tao Y, editors. Targeting Trafficking in Drug Development. Cham: Springer International Publishing; 2018. pp. 155-90. [DOI: 10.1007/164_2017_55] [Cited by in Crossref: 3] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
13 Neira JL, Rizzuti B, Ortega-Alarcón D, Giudici AM, Abián O, Fárez-Vidal ME, Velázquez-Campoy A. The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73. Biochim Biophys Acta Gen Subj 2021;1865:129914. [PMID: 33872756 DOI: 10.1016/j.bbagen.2021.129914] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
14 Beaver SK, Mesa-Torres N, Pey AL, Timson DJ. NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms. Biochim Biophys Acta Proteins Proteom 2019;1867:663-76. [PMID: 31091472 DOI: 10.1016/j.bbapap.2019.05.002] [Cited by in Crossref: 35] [Cited by in F6Publishing: 32] [Article Influence: 11.7] [Reference Citation Analysis]
15 Salido E, Timson DJ, Betancor-fernández I, Palomino-morales R, Anoz-carbonell E, Pacheco-garcía JL, Medina M, Pey AL. Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1. JPM 2022;12:747. [DOI: 10.3390/jpm12050747] [Reference Citation Analysis]
16 Mesa-Torres N, Betancor-Fernández I, Oppici E, Cellini B, Salido E, Pey AL. Evolutionary Divergent Suppressor Mutations in Conformational Diseases. Genes (Basel) 2018;9:E352. [PMID: 30011855 DOI: 10.3390/genes9070352] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 2.8] [Reference Citation Analysis]
17 Vabulas RM. Ferroptosis-Related Flavoproteins: Their Function and Stability. Int J Mol Sci 2021;22:E430. [PMID: 33406703 DOI: 10.3390/ijms22010430] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
18 Pacheco-Garcia JL, Loginov D, Rizzuti B, Vankova P, Neira JL, Kavan D, Mesa-Torres N, Guzzi R, Man P, Pey AL. A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation. FEBS Lett 2021. [PMID: 34817874 DOI: 10.1002/1873-3468.14238] [Reference Citation Analysis]
19 Pey AL. Biophysical and functional perturbation analyses at cancer-associated P187 and K240 sites of the multifunctional NADP(H):quinone oxidoreductase 1. Int J Biol Macromol 2018;118:1912-23. [PMID: 30009918 DOI: 10.1016/j.ijbiomac.2018.07.051] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.8] [Reference Citation Analysis]
20 Dong H, Hao L, Zhang W, Zhong W, Guo W, Yue R, Sun X, Zhou Z. Activation of AhR-NQO1 Signaling Pathway Protects Against Alcohol-Induced Liver Injury by Improving Redox Balance. Cell Mol Gastroenterol Hepatol 2021;12:793-811. [PMID: 34082111 DOI: 10.1016/j.jcmgh.2021.05.013] [Reference Citation Analysis]
21 Pacheco-Garcia JL, Anoz-Carbonell E, Vankova P, Kannan A, Palomino-Morales R, Mesa-Torres N, Salido E, Man P, Medina M, Naganathan AN, Pey AL. Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue. Redox Biol 2021;46:102112. [PMID: 34537677 DOI: 10.1016/j.redox.2021.102112] [Reference Citation Analysis]
22 Muñoz IG, Morel B, Medina‐carmona E, Pey AL. A mechanism for cancer‐associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R. FEBS Lett 2017;591:2826-35. [DOI: 10.1002/1873-3468.12772] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 3.4] [Reference Citation Analysis]
23 Megarity CF, Timson DJ. Cancer-associated variants of human NQO1: impacts on inhibitor binding and cooperativity. Biosci Rep 2019;39:BSR20191874. [PMID: 31431515 DOI: 10.1042/BSR20191874] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 1.3] [Reference Citation Analysis]
24 Pey AL, Megarity CF, Timson DJ. NAD(P)H quinone oxidoreductase (NQO1): an enzyme which needs just enough mobility, in just the right places. Biosci Rep 2019;39:BSR20180459. [PMID: 30518535 DOI: 10.1042/BSR20180459] [Cited by in Crossref: 21] [Cited by in F6Publishing: 5] [Article Influence: 7.0] [Reference Citation Analysis]