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For: Kramer J, Himmel HM, Lindqvist A, Stoelzle-Feix S, Chaudhary KW, Li D, Bohme GA, Bridgland-Taylor M, Hebeisen S, Fan J, Renganathan M, Imredy J, Humphries ESA, Brinkwirth N, Strassmaier T, Ohtsuki A, Danker T, Vanoye C, Polonchuk L, Fermini B, Pierson JB, Gintant G. Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells. Sci Rep 2020;10:5627. [PMID: 32221320 DOI: 10.1038/s41598-020-62344-w] [Cited by in Crossref: 23] [Cited by in F6Publishing: 23] [Article Influence: 11.5] [Reference Citation Analysis]
Number Citing Articles
1 Watt ED, Lee T, Feng SL, Kilfoil P, Ackley D, Keefer C, Wisialowski T, Jenkinson S. Use of high throughput ion channel profiling and statistical modeling to predict off-target arrhythmia risk - One pharma's experience and perspective. J Pharmacol Toxicol Methods 2022;118:107213. [PMID: 36084863 DOI: 10.1016/j.vascn.2022.107213] [Reference Citation Analysis]
2 Pugsley MK, Koshman YE, de Korte T, Authier S, Winters BR, Curtis MJ. Safety pharmacology in 2022: Taking one small step for cardiovascular safety assay development but one giant leap for regulatory drug safety assessment. Journal of Pharmacological and Toxicological Methods 2022. [DOI: 10.1016/j.vascn.2022.107206] [Reference Citation Analysis]
3 Windley MJ, Farr J, Tebay C, Vandenberg JI, Hill AP. Translating the measurement of hERG kinetics and drug block for CiPA to a high throughput platform. J Pharmacol Toxicol Methods 2022;:107192. [PMID: 35750310 DOI: 10.1016/j.vascn.2022.107192] [Reference Citation Analysis]
4 Lei CL, Fabbri A, Whittaker DG, Clerx M, Windley MJ, Hill AP, Mirams GR, de Boer TP. A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer. Wellcome Open Res 2020;5:152. [PMID: 34805549 DOI: 10.12688/wellcomeopenres.15968.2] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
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6 Pesti K, Földi MC, Zboray K, Toth AV, Lukacs P, Mike A. Characterization of Compound-Specific, Concentration-Independent Biophysical Properties of Sodium Channel Inhibitor Mechanism of Action Using Automated Patch-Clamp Electrophysiology. Front Pharmacol 2021;12:738460. [PMID: 34497526 DOI: 10.3389/fphar.2021.738460] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
7 Rotordam MG, Obergrussberger A, Brinkwirth N, Takasuna K, Becker N, Horváth A, Goetze TA, Rapedius M, Furukawa H, Hasegawa Y, Oka T, Fertig N, Stoelzle-Feix S. Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment. J Pharmacol Toxicol Methods 2021;112:107125. [PMID: 34500078 DOI: 10.1016/j.vascn.2021.107125] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 4.0] [Reference Citation Analysis]
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9 Pesti K, Földi MC, Zboray K, Toth AV, Lukacs P, Mike A. Compound-specific, concentration-independent biophysical properties of sodium channel inhibitor mechanism of action.. [DOI: 10.1101/2021.07.05.451191] [Reference Citation Analysis]
10 Mathie A, Veale EL, Golluscio A, Holden RG, Walsh Y. Pharmacological Approaches to Studying Potassium Channels. Handb Exp Pharmacol 2021;267:83-111. [PMID: 34195873 DOI: 10.1007/164_2021_502] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
11 Pugsley MK, Koshman Y, de Korte T, Authier S, Curtis MJ. Safety pharmacology during the COVID pandemic. J Pharmacol Toxicol Methods 2021;:107089. [PMID: 34182120 DOI: 10.1016/j.vascn.2021.107089] [Reference Citation Analysis]
12 Qu Y, Gao B, Arimura Z, Fang M, Vargas HM. Comprehensive in vitro pro-arrhythmic assays demonstrate that omecamtiv mecarbil has low pro-arrhythmic risk. Clin Transl Sci 2021;14:1600-10. [PMID: 33955165 DOI: 10.1111/cts.13039] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
13 Kreutzer FP, Meinecke A, Schmidt K, Fiedler J, Thum T. Alternative strategies in cardiac preclinical research and new clinical trial formats. Cardiovasc Res 2021:cvab075. [PMID: 33693475 DOI: 10.1093/cvr/cvab075] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 4.0] [Reference Citation Analysis]
14 Iop L. Toward the Effective Bioengineering of a Pathological Tissue for Cardiovascular Disease Modeling: Old Strategies and New Frontiers for Prevention, Diagnosis, and Therapy. Front Cardiovasc Med 2020;7:591583. [PMID: 33748193 DOI: 10.3389/fcvm.2020.591583] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
15 Lemoine MD, Christ T. Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: The New Working Horse in Cardiovascular Pharmacology? J Cardiovasc Pharmacol 2021;77:265-6. [PMID: 33433138 DOI: 10.1097/FJC.0000000000000981] [Reference Citation Analysis]
16 Okada JI, Yoshinaga T, Washio T, Sawada K, Sugiura S, Hisada T. Chloroquine and hydroxychloroquine provoke arrhythmias at concentrations higher than those clinically used to treat COVID-19: A simulation study. Clin Transl Sci 2021;14:1092-100. [PMID: 33404133 DOI: 10.1111/cts.12976] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 4.0] [Reference Citation Analysis]
17 Dou HH, Mallari R, Pipathsouk A, Das A, Lo MC. An Automated High-Throughput Fluorescence In Situ Hybridization (FISH) Assay Platform for Use in the Identification and Optimization of siRNA-Based Therapeutics. SLAS Discov 2021;26:281-91. [PMID: 33016168 DOI: 10.1177/2472555220960045] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
18 Stevens EB, Wright PD. Ion channel discovery – partnering to access specialized expertise. Future Drug Discovery 2020;2:FDD47. [DOI: 10.4155/fdd-2020-0020] [Reference Citation Analysis]
19 Vargas HM, Rolf MG, Wisialowski TA, Achanzar W, Bahinski A, Bass A, Benson CT, Chaudhary KW, Couvreur N, Dota C, Engwall MJ, Michael Foley C, Gallacher D, Greiter-Wilke A, Guillon JM, Guth B, Himmel HM, Hegele-Hartung C, Ito M, Jenkinson S, Chiba K, Lagrutta A, Levesque P, Martel E, Okai Y, Peri R, Pointon A, Qu Y, Teisman A, Traebert M, Yoshinaga T, Gintant GA, Leishman DJ, Valentin JP. Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective. Clin Pharmacol Ther 2021;109:310-8. [PMID: 32866317 DOI: 10.1002/cpt.2029] [Cited by in Crossref: 27] [Cited by in F6Publishing: 28] [Article Influence: 13.5] [Reference Citation Analysis]
20 Stella Stoter AM, Hirt MN, Stenzig J, Weinberger F. Assessment of Cardiotoxicity With Stem Cell-based Strategies. Clin Ther 2020;42:1892-910. [PMID: 32938533 DOI: 10.1016/j.clinthera.2020.08.012] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
21 Brinkwirth N, Takasuna K, Doi M, Becker N, Obergrussberger A, Friis S, Furukawa H, Hasegawa Y, Oka T, Ohtsuki A, Fertig N, Stoelzle-feix S. Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment. Journal of Pharmacological and Toxicological Methods 2020;105:106884. [DOI: 10.1016/j.vascn.2020.106884] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 6.5] [Reference Citation Analysis]
22 Obergrussberger A, Friis S, Brüggemann A, Fertig N. Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade. Expert Opin Drug Discov 2021;16:1-5. [PMID: 32646308 DOI: 10.1080/17460441.2020.1791079] [Cited by in Crossref: 23] [Cited by in F6Publishing: 15] [Article Influence: 11.5] [Reference Citation Analysis]
23 Lei CL, Fabbri A, Whittaker DG, Clerx M, Windley MJ, Hill AP, Mirams GR, de Boer TP. A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer. Wellcome Open Res 2020;5:152. [DOI: 10.12688/wellcomeopenres.15968.1] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]