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For: van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, Clevers H. Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature. 2005;435:959-963. [PMID: 15959515 DOI: 10.1038/nature03659] [Cited by in Crossref: 1069] [Cited by in F6Publishing: 1016] [Article Influence: 66.8] [Reference Citation Analysis]
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4 Tamagawa Y, Ishimura N, Uno G, Yuki T, Kazumori H, Ishihara S, Amano Y, Kinoshita Y. Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus. Lab Invest. 2012;92:896-909. [PMID: 22449796 DOI: 10.1038/labinvest.2012.56] [Cited by in Crossref: 29] [Cited by in F6Publishing: 28] [Article Influence: 3.2] [Reference Citation Analysis]
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7 Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 2007;445:776-780. [PMID: 17259973 DOI: 10.1038/nature05571] [Cited by in Crossref: 1121] [Cited by in F6Publishing: 995] [Article Influence: 80.1] [Reference Citation Analysis]
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11 Bar Y, Efrat S. The NOTCH Pathway in β-Cell Growth and Differentiation. The Pancreatic Beta Cell. Elsevier; 2014. pp. 391-405. [DOI: 10.1016/b978-0-12-800174-5.00015-6] [Cited by in Crossref: 11] [Cited by in F6Publishing: 4] [Article Influence: 1.6] [Reference Citation Analysis]
12 Takebe N, Nguyen D, Yang SX. Targeting notch signaling pathway in cancer: clinical development advances and challenges. Pharmacol Ther. 2014;141:140-149. [PMID: 24076266 DOI: 10.1016/j.pharmthera.2013.09.005] [Cited by in Crossref: 240] [Cited by in F6Publishing: 212] [Article Influence: 30.0] [Reference Citation Analysis]
13 Domingo-Domenech J, Vidal SJ, Rodriguez-Bravo V, Castillo-Martin M, Quinn SA, Rodriguez-Barrueco R, Bonal DM, Charytonowicz E, Gladoun N, de la Iglesia-Vicente J. Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells. Cancer Cell. 2012;22:373-388. [PMID: 22975379 DOI: 10.1016/j.ccr.2012.07.016] [Cited by in Crossref: 277] [Cited by in F6Publishing: 248] [Article Influence: 30.8] [Reference Citation Analysis]
14 Sato T, Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science. 2013;340:1190-1194. [PMID: 23744940 DOI: 10.1126/science.1234852] [Cited by in Crossref: 680] [Cited by in F6Publishing: 582] [Article Influence: 85.0] [Reference Citation Analysis]
15 Souazé F, Bou-Hanna C, Kandel C, Leclair F, Devallière J, Charreau B, Bézieau S, Mosnier JF, Laboisse CL. Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study. PLoS One 2013;8:e55904. [PMID: 23409082 DOI: 10.1371/journal.pone.0055904] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
16 Bounaama A, Djerdjouri B, Laroche-Clary A, Le Morvan V, Robert J. Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-β1 and HES-1 transcripts in 1,2-dimethylhydrazine-colon carcinogenesis in mice. Toxicology 2012;302:308-17. [PMID: 22982865 DOI: 10.1016/j.tox.2012.08.014] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 2.1] [Reference Citation Analysis]
17 Chen W, Zhuo M, Lu X, Xia X, Zhao Y, Huang Z, Xu J, Li W, Yu C. SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression. Int J Biol Sci 2018;14:2051-64. [PMID: 30585268 DOI: 10.7150/ijbs.28576] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 2.0] [Reference Citation Analysis]
18 Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albà MM, Torres F. Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad Sci USA. 2009;106:6315-6320. [PMID: 19325125 DOI: 10.1073/pnas.081322] [Reference Citation Analysis]
19 Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, Devgan V, Lieb J, Raffoul W, Hohl D, Neel V, Garlick J, Chiorino G, Dotto GP. Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases. Genes Dev 2007;21:562-77. [PMID: 17344417 DOI: 10.1101/gad.1484707] [Cited by in Crossref: 215] [Cited by in F6Publishing: 205] [Article Influence: 15.4] [Reference Citation Analysis]
20 Heib M, Rose-John S, Adam D. Necroptosis, ADAM proteases and intestinal (dys)function. Int Rev Cell Mol Biol 2020;353:83-152. [PMID: 32381179 DOI: 10.1016/bs.ircmb.2020.02.001] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
21 Dunkin D, Iuga AC, Mimouna S, Harris CL, Haure-Mirande JV, Bozec D, Yeretssian G, Dahan S. Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma. Oncotarget 2018;9:33536-48. [PMID: 30323897 DOI: 10.18632/oncotarget.26086] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
22 Li Y, Zhang T, Guo C, Geng M, Gai S, Qi W, Li Z, Song Y, Luo X, Wang N. Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1. Pathog Dis. 2020;78. [PMID: 32166323 DOI: 10.1093/femspd/ftaa016] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 6.0] [Reference Citation Analysis]
23 Ricca BL, Venugopalan G, Furuta S, Tanner K, Orellana WA, Reber CD, Brownfield DG, Bissell MJ, Fletcher DA. Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling. Elife 2018;7:e26161. [PMID: 29560858 DOI: 10.7554/eLife.26161] [Cited by in Crossref: 18] [Cited by in F6Publishing: 11] [Article Influence: 6.0] [Reference Citation Analysis]
24 Kuratnik A, Giardina C. Intestinal organoids as tissue surrogates for toxicological and pharmacological studies. Biochem Pharmacol. 2013;85:1721-1726. [PMID: 23623789 DOI: 10.1016/j.bcp.2013.04.016] [Cited by in Crossref: 31] [Cited by in F6Publishing: 22] [Article Influence: 3.9] [Reference Citation Analysis]
25 Hales EC, Taub JW, Matherly LH. New insights into Notch1 regulation of the PI3K–AKT–mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia. Cellular Signalling 2014;26:149-61. [DOI: 10.1016/j.cellsig.2013.09.021] [Cited by in Crossref: 101] [Cited by in F6Publishing: 93] [Article Influence: 14.4] [Reference Citation Analysis]
26 Groot AJ, Vooijs MA. The role of Adams in Notch signaling. Adv Exp Med Biol 2012;727:15-36. [PMID: 22399336 DOI: 10.1007/978-1-4614-0899-4_2] [Cited by in Crossref: 42] [Cited by in F6Publishing: 39] [Article Influence: 4.7] [Reference Citation Analysis]
27 Tagami S, Okochi M, Yanagida K, Ikuta A, Fukumori A, Matsumoto N, Ishizuka-Katsura Y, Nakayama T, Itoh N, Jiang J, Nishitomi K, Kamino K, Morihara T, Hashimoto R, Tanaka T, Kudo T, Chiba S, Takeda M. Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1. Mol Cell Biol 2008;28:165-76. [PMID: 17967888 DOI: 10.1128/MCB.00863-07] [Cited by in Crossref: 82] [Cited by in F6Publishing: 47] [Article Influence: 5.9] [Reference Citation Analysis]
28 Kim TH, Shivdasani RA. Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression. J Biol Chem. 2011;286:11427-11433. [PMID: 21282114 DOI: 10.1074/jbc.m110.188797] [Cited by in Crossref: 60] [Cited by in F6Publishing: 40] [Article Influence: 6.0] [Reference Citation Analysis]
29 Babaei-Jadidi R, Li N, Saadeddin A, Spencer-Dene B, Jandke A, Muhammad B, Ibrahim EE, Muraleedharan R, Abuzinadah M, Davis H, Lewis A, Watson S, Behrens A, Tomlinson I, Nateri AS. FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation. J Exp Med. 2011;208:295-312. [PMID: 21282377 DOI: 10.1084/jem.20100830] [Cited by in Crossref: 121] [Cited by in F6Publishing: 111] [Article Influence: 12.1] [Reference Citation Analysis]
30 Gregorieff A, Stange DE, Kujala P, Begthel H, van den Born M, Korving J, Peters PJ, Clevers H. The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium. Gastroenterology. 2009;137:1333-1345.e1-3. [PMID: 19549527 DOI: 10.1053/j.gastro.2009.06.044] [Cited by in Crossref: 151] [Cited by in F6Publishing: 144] [Article Influence: 12.6] [Reference Citation Analysis]
31 Kokubu H, Ohtsuka T, Kageyama R. Mash1 is required for neuroendocrine cell development in the glandular stomach. Genes Cells 2008;13:41-51. [PMID: 18173746 DOI: 10.1111/j.1365-2443.2007.01146.x] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 1.5] [Reference Citation Analysis]
32 Dorfman MD, Kerr B, Garcia-Rudaz C, Paredes AH, Dissen GA, Ojeda SR. Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development. Endocrinology 2011;152:5005-16. [PMID: 22028443 DOI: 10.1210/en.2011-1465] [Cited by in Crossref: 18] [Cited by in F6Publishing: 15] [Article Influence: 1.8] [Reference Citation Analysis]
33 Niranjan T, Bielesz B, Gruenwald A, Ponda MP, Kopp JB, Thomas DB, Susztak K. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat Med 2008;14:290-8. [DOI: 10.1038/nm1731] [Cited by in Crossref: 279] [Cited by in F6Publishing: 255] [Article Influence: 21.5] [Reference Citation Analysis]
34 Imbimbo BP, Hutter-Paier B, Villetti G, Facchinetti F, Cenacchi V, Volta R, Lanzillotta A, Pizzi M, Windisch M. CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease. Br J Pharmacol 2009;156:982-93. [PMID: 19239474 DOI: 10.1111/j.1476-5381.2008.00097.x] [Cited by in Crossref: 59] [Cited by in F6Publishing: 55] [Article Influence: 4.9] [Reference Citation Analysis]
35 Haider S, Meinhardt G, Velicky P, Otti GR, Whitley G, Fiala C, Pollheimer J, Knöfler M. Notch signaling plays a critical role in motility and differentiation of human first-trimester cytotrophoblasts. Endocrinology 2014;155:263-74. [PMID: 24189144 DOI: 10.1210/en.2013-1455] [Cited by in Crossref: 34] [Cited by in F6Publishing: 34] [Article Influence: 4.3] [Reference Citation Analysis]
36 Nakamura Y, Kimura S, Hase K. M cell-dependent antigen uptake on follicle-associated epithelium for mucosal immune surveillance. Inflamm Regen 2018;38:15. [PMID: 30186536 DOI: 10.1186/s41232-018-0072-y] [Cited by in Crossref: 16] [Cited by in F6Publishing: 10] [Article Influence: 5.3] [Reference Citation Analysis]
37 Fletcher AG, Murray PJ, Maini PK. Multiscale modelling of intestinal crypt organization and carcinogenesis. Math Models Methods Appl Sci 2015;25:2563-85. [DOI: 10.1142/s0218202515400187] [Cited by in Crossref: 18] [Article Influence: 3.0] [Reference Citation Analysis]
38 Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni CW, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D. Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development 2015;142:1050-61. [PMID: 25758220 DOI: 10.1242/dev.119180] [Cited by in Crossref: 80] [Cited by in F6Publishing: 58] [Article Influence: 13.3] [Reference Citation Analysis]
39 Singh BN, Singh HB, Singh A, Naqvi AH, Singh BR. Dietary phytochemicals alter epigenetic events and signaling pathways for inhibition of metastasis cascade: phytoblockers of metastasis cascade. Cancer Metastasis Rev 2014;33:41-85. [PMID: 24390421 DOI: 10.1007/s10555-013-9457-1] [Cited by in Crossref: 41] [Cited by in F6Publishing: 35] [Article Influence: 6.8] [Reference Citation Analysis]
40 Suman S, Das TP, Ankem MK, Damodaran C. Targeting Notch Signaling in Colorectal Cancer. Curr Colorectal Cancer Rep. 2014;10:411-416. [PMID: 25395896 DOI: 10.1007/s11888-014-0252-3] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 2.9] [Reference Citation Analysis]
41 Parang B, Rosenblatt D, Williams AD, Washington MK, Revetta F, Short SP, Reddy VK, Hunt A, Shroyer NF, Engel ME, Hiebert SW, Williams CS. The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation. FASEB J 2015;29:786-95. [PMID: 25398765 DOI: 10.1096/fj.14-254284] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 1.1] [Reference Citation Analysis]
42 Chatterjee S, Sil PC. Targeting the crosstalks of Wnt pathway with Hedgehog and Notch for cancer therapy. Pharmacol Res 2019;142:251-61. [PMID: 30826456 DOI: 10.1016/j.phrs.2019.02.027] [Cited by in Crossref: 34] [Cited by in F6Publishing: 28] [Article Influence: 17.0] [Reference Citation Analysis]
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45 Ratsimandresy RA, Indramohan M, Dorfleutner A, Stehlik C. The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway. Cell Mol Immunol 2017;14:127-42. [PMID: 27524110 DOI: 10.1038/cmi.2016.35] [Cited by in Crossref: 63] [Cited by in F6Publishing: 61] [Article Influence: 12.6] [Reference Citation Analysis]
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47 Shen Z, Liu Y, Dewidar B, Hu J, Park O, Feng T, Xu C, Yu C, Li Q, Meyer C, Ilkavets I, Müller A, Stump-Guthier C, Munker S, Liebe R, Zimmer V, Lammert F, Mertens PR, Li H, Ten Dijke P, Augustin HG, Li J, Gao B, Ebert MP, Dooley S, Li Y, Weng HL. Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression. Am J Pathol 2016;186:1874-89. [PMID: 27171900 DOI: 10.1016/j.ajpath.2016.03.010] [Cited by in Crossref: 21] [Cited by in F6Publishing: 21] [Article Influence: 4.2] [Reference Citation Analysis]
48 Markstein M. Modeling colorectal cancer as a 3-dimensional disease in a dish: the case for drug screening using organoids, zebrafish, and fruit flies. Drug Discov Today Technol 2013;10:e73-81. [PMID: 24050233 DOI: 10.1016/j.ddtec.2012.12.005] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 1.6] [Reference Citation Analysis]
49 Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R. Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors. Biochem Biophys Res Commun. 2017;482:1296-1303. [PMID: 27939883 DOI: 10.1016/j.bbrc.2016.12.031] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 1.4] [Reference Citation Analysis]
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