BPG is committed to discovery and dissemination of knowledge
Cited by in F6Publishing
For: Romashkova JA, Makarov SS. NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature. 1999;401:86-90. [PMID: 10485711 DOI: 10.1038/43474] [Cited by in Crossref: 1363] [Cited by in F6Publishing: 1323] [Article Influence: 59.3] [Reference Citation Analysis]
Number Citing Articles
1 Heussler VT, Kuenzi P, Fraga F, Schwab RA, Hemmings BA, Dobbelaere DAE. The Akt/PKB pathway is constitutively activated in Theileria-transformed leucocytes, but does not directly control constitutive NF-kappaB activation. Cell Microbiol 2001;3:537-50. [DOI: 10.1046/j.1462-5822.2001.00134.x] [Cited by in Crossref: 43] [Cited by in F6Publishing: 38] [Article Influence: 2.0] [Reference Citation Analysis]
2 Kumar N, Srivastava S, Burek M, Förster CY, Roy P. Assessment of estradiol-induced gene regulation and proliferation in an immortalized mouse immature Sertoli cell line. Life Sci 2016;148:268-78. [PMID: 26784849 DOI: 10.1016/j.lfs.2016.01.027] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
3 Apte SM, Bucana CD, Killion JJ, Gershenson DM, Fidler IJ. Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines. Gynecologic Oncology 2004;93:78-86. [DOI: 10.1016/j.ygyno.2003.12.041] [Cited by in Crossref: 56] [Cited by in F6Publishing: 50] [Article Influence: 3.1] [Reference Citation Analysis]
4 Xu H, He L, Feng X, Kapoor A, Tang D. Specific Reduction of Fas-Associated Protein with Death Domain (FADD) in Clear Cell Renal Cell Carcinoma. Cancer Investigation 2009;27:836-43. [DOI: 10.1080/07357900902849681] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.2] [Reference Citation Analysis]
5 Vidal S, Bouzaher YH, El Motiam A, Seoane R, Rivas C. Overview of the regulation of the class IA PI3K/AKT pathway by SUMO. Semin Cell Dev Biol 2021:S1084-9521(21)00275-5. [PMID: 34753687 DOI: 10.1016/j.semcdb.2021.10.012] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
6 Cherla RP, Ganju RK. Stromal cell-derived factor 1 alpha-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways. J Immunol 2001;166:3067-74. [PMID: 11207257 DOI: 10.4049/jimmunol.166.5.3067] [Cited by in Crossref: 68] [Cited by in F6Publishing: 63] [Article Influence: 3.2] [Reference Citation Analysis]
7 Huang C, Fujimura M, Noshita N, Chang Y, Chan PH. SOD1 Down-Regulates NF-κB and c-Myc Expression in Mice after Transient Focal Cerebral Ischemia. J Cereb Blood Flow Metab 2001;21:163-73. [DOI: 10.1097/00004647-200102000-00008] [Cited by in Crossref: 88] [Cited by in F6Publishing: 86] [Article Influence: 14.7] [Reference Citation Analysis]
8 Ganesan LP, Wei G, Pengal RA, Moldovan L, Moldovan N, Ostrowski MC, Tridandapani S. The Serine/Threonine Kinase Akt Promotes Fcγ Receptor-mediated Phagocytosis in Murine Macrophages through the Activation of p70S6 Kinase. Journal of Biological Chemistry 2004;279:54416-25. [DOI: 10.1074/jbc.m408188200] [Cited by in Crossref: 54] [Cited by in F6Publishing: 35] [Article Influence: 3.0] [Reference Citation Analysis]
9 Chong ZZ, Kang JQ, Maiese K. Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades. J Cereb Blood Flow Metab. 2002;22:503-514. [PMID: 11973422 DOI: 10.1097/00004647-200205000-00001] [Cited by in Crossref: 135] [Cited by in F6Publishing: 137] [Article Influence: 6.8] [Reference Citation Analysis]
10 Madrid LV, Mayo MW, Reuther JY, Baldwin AS Jr. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J Biol Chem 2001;276:18934-40. [PMID: 11259436 DOI: 10.1074/jbc.M101103200] [Cited by in Crossref: 606] [Cited by in F6Publishing: 209] [Article Influence: 28.9] [Reference Citation Analysis]
11 Suzuki T, Yamashita C, Zemans RL, Briones N, Van Linden A, Downey GP. Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway. Am J Respir Cell Mol Biol 2009;41:742-55. [PMID: 19307610 DOI: 10.1165/rcmb.2008-0157OC] [Cited by in Crossref: 51] [Cited by in F6Publishing: 31] [Article Influence: 3.9] [Reference Citation Analysis]
12 Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, McFerran B, Wyche J, Kolch W, Sedivy JM. Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation. Mol Cell Biol. 2001;21:7207-7217. [PMID: 11585904 DOI: 10.1128/MCB.21.21.7207-7217.2001] [Cited by in Crossref: 271] [Cited by in F6Publishing: 133] [Article Influence: 12.9] [Reference Citation Analysis]
13 Rudelius M, Pittaluga S, Nishizuka S, Pham TH, Fend F, Jaffe ES, Quintanilla-Martinez L, Raffeld M. Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma. Blood 2006;108:1668-76. [PMID: 16645163 DOI: 10.1182/blood-2006-04-015586] [Cited by in Crossref: 183] [Cited by in F6Publishing: 182] [Article Influence: 11.4] [Reference Citation Analysis]
14 Tsai CY, Chang AY, Chan JY, Chan SH. Activation of PI3K/Akt signaling in rostral ventrolateral medulla impairs brain stem cardiovascular regulation that underpins circulatory depression during mevinphos intoxication. Biochem Pharmacol 2014;88:75-85. [PMID: 24462917 DOI: 10.1016/j.bcp.2014.01.014] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 1.4] [Reference Citation Analysis]
15 Kaufman CK, Fuchs E. It's got you covered. NF-kappaB in the epidermis. J Cell Biol 2000;149:999-1004. [PMID: 10831603 DOI: 10.1083/jcb.149.5.999] [Cited by in Crossref: 95] [Cited by in F6Publishing: 86] [Article Influence: 4.3] [Reference Citation Analysis]
16 Messeha SS, Zarmouh NO, Mendonca P, Cotton C, Soliman KFA. Molecular mechanism of gossypol mediating CCL2 and IL‑8 attenuation in triple‑negative breast cancer cells. Mol Med Rep 2020;22:1213-26. [PMID: 32627003 DOI: 10.3892/mmr.2020.11240] [Reference Citation Analysis]
17 Plate JM. PI3-Kinase Regulates Survival of Chronic Lymphocytic Leukemia B-Cells by Preventing Caspase 8 Activation. Leukemia & Lymphoma 2009;45:1519-29. [DOI: 10.1080/10428190410001683642] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 1.6] [Reference Citation Analysis]
18 Moon A. Differential functions of Ras for malignant phenotypic conversion. Arch Pharm Res 2006;29:113-22. [PMID: 16526274 DOI: 10.1007/BF02974271] [Cited by in Crossref: 22] [Cited by in F6Publishing: 6] [Article Influence: 1.4] [Reference Citation Analysis]
19 Lopez-Bergami P, Fitchman B, Ronai Z. Understanding signaling cascades in melanoma. Photochem Photobiol 2008;84:289-306. [PMID: 18086245 DOI: 10.1111/j.1751-1097.2007.00254.x] [Cited by in Crossref: 56] [Cited by in F6Publishing: 55] [Article Influence: 3.7] [Reference Citation Analysis]
20 Wang X, Khoshaba R, Shen Y, Cao Y, Lin M, Zhu Y, Cao Z, Liao DF, Cao D. Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice. Front Cell Dev Biol 2021;9:632805. [PMID: 33644071 DOI: 10.3389/fcell.2021.632805] [Reference Citation Analysis]
21 Roth I, Leroy V, Kwon HM, Martin PY, Féraille E, Hasler U. Osmoprotective transcription factor NFAT5/TonEBP modulates nuclear factor-kappaB activity. Mol Biol Cell. 2010;21:3459-3474. [PMID: 20685965 DOI: 10.1091/mbc.e10-02-0133] [Cited by in Crossref: 68] [Cited by in F6Publishing: 59] [Article Influence: 5.7] [Reference Citation Analysis]
22 Burns TF, el-Deiry WS. Cell death signaling in maligancy. Cancer Treat Res 2003;115:319-43. [PMID: 12613203 DOI: 10.1007/0-306-48158-8_13] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 0.5] [Reference Citation Analysis]
23 Beck M, Karch C, Wiese S, Sendtner M. Motoneuron cell death and neurotrophic factors: Basic models for development of new therapeutic strategies in ALS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 2009;2:s55-68. [DOI: 10.1080/146608201300079454] [Cited by in Crossref: 14] [Cited by in F6Publishing: 9] [Article Influence: 1.1] [Reference Citation Analysis]
24 Gupta S, Stuffrein S, Plattner R, Tencati M, Gray C, Whang YE, Stanbridge EJ. Role of phosphoinositide 3-kinase in the aggressive tumor growth of HT1080 human fibrosarcoma cells. Mol Cell Biol 2001;21:5846-56. [PMID: 11486024 DOI: 10.1128/MCB.21.17.5846-5856.2001] [Cited by in Crossref: 20] [Cited by in F6Publishing: 10] [Article Influence: 1.0] [Reference Citation Analysis]
25 Lee JY, Kim HS, Song YS. Genistein as a Potential Anticancer Agent against Ovarian Cancer. J Tradit Complement Med 2012;2:96-104. [PMID: 24716121 DOI: 10.1016/s2225-4110(16)30082-7] [Cited by in Crossref: 55] [Cited by in F6Publishing: 25] [Article Influence: 6.9] [Reference Citation Analysis]
26 Wang Y, Zhu Z, Church TD, Lugogo NL, Que LG, Francisco D, Ingram JL, Huggins M, Beaver DM, Wright JR, Kraft M. SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. J Immunol 2012;188:3371-81. [PMID: 22371396 DOI: 10.4049/jimmunol.1100573] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 1.4] [Reference Citation Analysis]
27 West KA, Sianna Castillo S, Dennis PA. Activation of the PI3K/Akt pathway and chemotherapeutic resistance. Drug Resistance Updates 2002;5:234-48. [DOI: 10.1016/s1368-7646(02)00120-6] [Cited by in Crossref: 390] [Cited by in F6Publishing: 196] [Article Influence: 19.5] [Reference Citation Analysis]
28 Son D, Na YR, Hwang ES, Seok SH. Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt and Bad phosphorylation. J Biol Chem 2014;289:6225-35. [PMID: 24421315 DOI: 10.1074/jbc.M113.508994] [Cited by in Crossref: 22] [Cited by in F6Publishing: 12] [Article Influence: 2.8] [Reference Citation Analysis]
29 Esteva FJ, Hortobagyi GN, Sahin AA, Smith TL, Chin DM, Liang SY, Pusztai L, Buzdar AU, Bacus SS. Expression of erbB/HER receptors, heregulin and P38 in primary breast cancer using quantitative immunohistochemistry. Pathol Oncol Res. 2001;7:171-177. [PMID: 11692142 DOI: 10.1007/BF03032345] [Cited by in Crossref: 50] [Cited by in F6Publishing: 20] [Article Influence: 2.5] [Reference Citation Analysis]
30 Yoshida S, Narita T, Koshida S, Ohta S, Takeuchi Y. TRAIL/Apo2L ligands induce apoptosis in malignant rhabdoid tumor cell lines. Pediatr Res 2003;54:709-17. [PMID: 12904602 DOI: 10.1203/01.PDR.0000085038.53151.D0] [Cited by in Crossref: 10] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
31 Saleem M, Afaq F, Adhami VM, Mukhtar H. Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 2004;23:5203-14. [PMID: 15122342 DOI: 10.1038/sj.onc.1207641] [Cited by in Crossref: 171] [Cited by in F6Publishing: 147] [Article Influence: 9.5] [Reference Citation Analysis]
32 Martin LJ. Fucoxanthin and Its Metabolite Fucoxanthinol in Cancer Prevention and Treatment. Mar Drugs 2015;13:4784-98. [PMID: 26264004 DOI: 10.3390/md13084784] [Cited by in Crossref: 53] [Cited by in F6Publishing: 48] [Article Influence: 7.6] [Reference Citation Analysis]
33 Otsuki T, Nagashima T, Komatsu N, Kirito K, Furukawa Y, Kobayashi Si S, Liu JM, Ozawa K. Phosphorylation of Fanconi anemia protein, FANCA, is regulated by Akt kinase. Biochem Biophys Res Commun 2002;291:628-34. [PMID: 11855836 DOI: 10.1006/bbrc.2002.6504] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 0.6] [Reference Citation Analysis]
34 Ohta T, Ohmichi M, Hayasaka T, Mabuchi S, Saitoh M, Kawagoe J, Takahashi K, Igarashi H, Du B, Doshida M. Inhibition of phosphatidylinositol 3-kinase increases efficacy of cisplatin in in vivo ovarian cancer models. Endocrinology. 2006;147:1761-1769. [PMID: 16396982 DOI: 10.1210/en.2005-1450] [Cited by in Crossref: 61] [Cited by in F6Publishing: 59] [Article Influence: 3.8] [Reference Citation Analysis]
35 Tsuruta F, Masuyama N, Gotoh Y. The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. J Biol Chem. 2002;277:14040-14047. [PMID: 11842081 DOI: 10.1074/jbc.m108975200] [Cited by in Crossref: 253] [Cited by in F6Publishing: 77] [Article Influence: 12.7] [Reference Citation Analysis]
36 Liu J, Tian Z, Gao B, Kunos G. Dose-dependent activation of antiapoptotic and proapoptotic pathways by ethanol treatment in human vascular endothelial cells: differential involvement of adenosine. J Biol Chem. 2002;277:20927-20933. [PMID: 11919181 DOI: 10.1074/jbc.m110712200] [Cited by in Crossref: 62] [Cited by in F6Publishing: 17] [Article Influence: 3.1] [Reference Citation Analysis]
37 Uzumcu M, Dirks KA, Skinner MK. Inhibition of platelet-derived growth factor actions in the embryonic testis influences normal cord development and morphology. Biol Reprod 2002;66:745-53. [PMID: 11870082 DOI: 10.1095/biolreprod66.3.745] [Cited by in Crossref: 30] [Cited by in F6Publishing: 31] [Article Influence: 1.5] [Reference Citation Analysis]
38 Li F, Zhang J, Arfuso F, Chinnathambi A, Zayed ME, Alharbi SA, Kumar AP, Ahn KS, Sethi G. NF-κB in cancer therapy. Arch Toxicol 2015;89:711-31. [PMID: 25690730 DOI: 10.1007/s00204-015-1470-4] [Cited by in Crossref: 115] [Cited by in F6Publishing: 112] [Article Influence: 16.4] [Reference Citation Analysis]
39 Vander Heiden MG, Plas DR, Rathmell JC, Fox CJ, Harris MH, Thompson CB. Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol Cell Biol 2001;21:5899-912. [PMID: 11486029 DOI: 10.1128/MCB.21.17.5899-5912.2001] [Cited by in Crossref: 374] [Cited by in F6Publishing: 174] [Article Influence: 17.8] [Reference Citation Analysis]
40 Carvalheira JB, Calegari VC, Zecchin HG, Nadruz W Jr, Guimarães RB, Ribeiro EB, Franchini KG, Velloso LA, Saad MJ. The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance. Endocrinology 2003;144:5604-14. [PMID: 12960006 DOI: 10.1210/en.2003-0788] [Cited by in Crossref: 45] [Cited by in F6Publishing: 43] [Article Influence: 2.4] [Reference Citation Analysis]
41 Jin KL, Mao XO, Greenberg DA. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc Natl Acad Sci U S A 2000;97:10242-7. [PMID: 10963684 DOI: 10.1073/pnas.97.18.10242] [Cited by in Crossref: 507] [Cited by in F6Publishing: 494] [Article Influence: 23.0] [Reference Citation Analysis]
42 Nakayama M, Hisatsune J, Yamasaki E, Isomoto H, Kurazono H, Hatakeyama M, Azuma T, Yamaoka Y, Yahiro K, Moss J. Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signaling pathway. J Biol Chem. 2009;284:1612-1619. [PMID: 18996844 DOI: 10.1074/jbc.m806981200] [Cited by in Crossref: 88] [Cited by in F6Publishing: 63] [Article Influence: 6.3] [Reference Citation Analysis]
43 Jo H, Zhang R, Zhang H, McKinsey TA, Shao J, Beauchamp RD, Ballard DW, Liang P. NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis. Oncogene. 2000;19:841-849. [PMID: 10702792 DOI: 10.1038/sj.onc.1203392] [Cited by in Crossref: 48] [Cited by in F6Publishing: 52] [Article Influence: 2.2] [Reference Citation Analysis]
44 Stanley G, Harvey K, Slivova V, Jiang J, Sliva D. Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells. Biochemical and Biophysical Research Communications 2005;330:46-52. [DOI: 10.1016/j.bbrc.2005.02.116] [Cited by in Crossref: 105] [Cited by in F6Publishing: 87] [Article Influence: 6.2] [Reference Citation Analysis]
45 Bournat J, Brown A, Soler AP. Wnt-1 dependent activation of the survival factor NF-?B in PC12 cells. J Neurosci Res 2000;61:21-32. [DOI: 10.1002/1097-4547(20000701)61:1<21::aid-jnr3>3.0.co;2-7] [Reference Citation Analysis]
46 McAuley JR, Freeman TJ, Ekambaram P, Lucas PC, McAllister-Lucas LM. CARMA3 Is a Critical Mediator of G Protein-Coupled Receptor and Receptor Tyrosine Kinase-Driven Solid Tumor Pathogenesis. Front Immunol. 2018;9:1887. [PMID: 30158935 DOI: 10.3389/fimmu.2018.01887] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 2.5] [Reference Citation Analysis]
47 Koul D, Yao Y, Abbruzzese JL, Yung WK, Reddy SA. Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway. J Biol Chem 2001;276:11402-8. [PMID: 11278366 DOI: 10.1074/jbc.M007806200] [Cited by in Crossref: 67] [Cited by in F6Publishing: 25] [Article Influence: 3.2] [Reference Citation Analysis]
48 Wierstra I, Alves J. The c‐myc Promoter: Still MysterY and Challenge. Elsevier; 2008. pp. 113-333. [DOI: 10.1016/s0065-230x(07)99004-1] [Cited by in Crossref: 133] [Cited by in F6Publishing: 79] [Article Influence: 9.5] [Reference Citation Analysis]
49 Bhardwaj A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S, Aggarwal BB. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood. 2007;109:2293-2302. [PMID: 17164350 DOI: 10.1182/blood-2006-02-003988] [Cited by in Crossref: 279] [Cited by in F6Publishing: 266] [Article Influence: 17.4] [Reference Citation Analysis]
50 Jiang Y, Chen D, Lyu S, Ling X, Krensky AM, Clayberger C. DQ 65–79, a Peptide Derived from HLA Class II, Induces IκB Expression. J Immunol 2002;168:3323-8. [DOI: 10.4049/jimmunol.168.7.3323] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.3] [Reference Citation Analysis]
51 Wang Z, Castresana MR, Newman WH. NF-κB is required for TNF-α-directed smooth muscle cell migration. FEBS Letters 2001;508:360-4. [DOI: 10.1016/s0014-5793(01)03109-x] [Cited by in Crossref: 53] [Cited by in F6Publishing: 15] [Article Influence: 2.5] [Reference Citation Analysis]
52 Shimamura T, Hsu T, Colburn NH, Bejcek BE. Activation of NF-κB Is Required for PDGF-B Chain to Transform NIH3T3 Cells. Experimental Cell Research 2002;274:157-67. [DOI: 10.1006/excr.2001.5449] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 0.3] [Reference Citation Analysis]
53 Liou JS, Chen C, Chen JS, Faller DV. Oncogenic Ras Mediates Apoptosis in Response to Protein Kinase C Inhibition through the Generation of Reactive Oxygen Species. Journal of Biological Chemistry 2000;275:39001-11. [DOI: 10.1074/jbc.m007154200] [Cited by in Crossref: 38] [Cited by in F6Publishing: 14] [Article Influence: 1.7] [Reference Citation Analysis]
54 Lin YH, Huang CJ, Chao JR, Chen ST, Lee SF, Yen JJ, Yang-Yen HF. Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor. Mol Cell Biol 2000;20:2734-42. [PMID: 10733576 DOI: 10.1128/MCB.20.8.2734-2742.2000] [Cited by in Crossref: 68] [Cited by in F6Publishing: 22] [Article Influence: 3.1] [Reference Citation Analysis]
55 Wu Q, Wang H, Zhao X, Shi Y, Jin M, Wan B, Xu H, Cheng Y, Ge H, Zhang Y. Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma. Oncogene 2013;32:5541-50. [PMID: 23851494 DOI: 10.1038/onc.2013.264] [Cited by in Crossref: 89] [Cited by in F6Publishing: 84] [Article Influence: 9.9] [Reference Citation Analysis]
56 Heng MC. Signaling pathways targeted by curcumin in acute and chronic injury: burns and photo-damaged skin. Int J Dermatol 2013;52:531-43. [PMID: 23231506 DOI: 10.1111/j.1365-4632.2012.05703.x] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.2] [Reference Citation Analysis]
57 Hu MC, Hung MC. Role of IkappaB kinase in tumorigenesis. Future Oncol 2005;1:67-78. [PMID: 16555977 DOI: 10.1517/14796694.1.1.67] [Cited by in Crossref: 23] [Cited by in F6Publishing: 24] [Article Influence: 1.4] [Reference Citation Analysis]
58 Saitoh M, Ohmichi M, Takahashi K, Kawagoe J, Ohta T, Doshida M, Takahashi T, Igarashi H, Mori-Abe A, Du B, Tsutsumi S, Kurachi H. Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-kappaB cascade in human breast cancer cells. Endocrinology 2005;146:4917-25. [PMID: 16123159 DOI: 10.1210/en.2004-1535] [Cited by in Crossref: 50] [Cited by in F6Publishing: 52] [Article Influence: 2.9] [Reference Citation Analysis]
59 Ohta E, Kawakami F, Kubo M, Obata F. LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations. FEBS Lett 2011;585:2165-70. [PMID: 21658387 DOI: 10.1016/j.febslet.2011.05.044] [Cited by in Crossref: 46] [Cited by in F6Publishing: 47] [Article Influence: 4.2] [Reference Citation Analysis]
60 Machida H, Nakajima S, Shikano N, Nishio J, Okada S, Asayama M, Shirai M, Kubota N. Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis. Cancer Sci 2005;96:911-7. [PMID: 16367912 DOI: 10.1111/j.1349-7006.2005.00125.x] [Cited by in Crossref: 35] [Cited by in F6Publishing: 27] [Article Influence: 2.2] [Reference Citation Analysis]
61 Sato S, Fujita N, Tsuruo T. Modulation of Akt kinase activity by binding to Hsp90. Proc Natl Acad Sci U S A 2000;97:10832-7. [PMID: 10995457 DOI: 10.1073/pnas.170276797] [Cited by in Crossref: 664] [Cited by in F6Publishing: 653] [Article Influence: 30.2] [Reference Citation Analysis]
62 Kang JH, Song KH, Woo JK, Park MH, Rhee MH, Choi C, Oh SH. Ginsenoside Rp1 from Panax ginseng exhibits anti-cancer activity by down-regulation of the IGF-1R/Akt pathway in breast cancer cells. Plant Foods Hum Nutr 2011;66:298-305. [PMID: 21748437 DOI: 10.1007/s11130-011-0242-4] [Cited by in Crossref: 47] [Cited by in F6Publishing: 34] [Article Influence: 4.7] [Reference Citation Analysis]
63 Achiron A, Feldman A, Mandel M, Gurevich M. Impaired Expression of Peripheral Blood Apoptotic-Related Gene Transcripts in Acute Multiple Sclerosis Relapse. Annals of the New York Academy of Sciences 2007;1107:155-67. [DOI: 10.1196/annals.1381.017] [Cited by in Crossref: 48] [Cited by in F6Publishing: 45] [Article Influence: 3.2] [Reference Citation Analysis]
64 Mockridge JW, Marber MS, Heads RJ. Activation of Akt during simulated ischemia/reperfusion in cardiac myocytes. Biochem Biophys Res Commun 2000;270:947-52. [PMID: 10772931 DOI: 10.1006/bbrc.2000.2522] [Cited by in Crossref: 64] [Cited by in F6Publishing: 59] [Article Influence: 2.9] [Reference Citation Analysis]
65 Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M. Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. J Exp Med 2012;209:713-28. [PMID: 22473959 DOI: 10.1084/jem.20111470] [Cited by in Crossref: 86] [Cited by in F6Publishing: 79] [Article Influence: 8.6] [Reference Citation Analysis]
66 Hsieh H, Wu C, Sun C, Liao C, Lau Y, Yang C. Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells. J Cell Physiol 2006;207:757-66. [DOI: 10.1002/jcp.20621] [Cited by in Crossref: 58] [Cited by in F6Publishing: 56] [Article Influence: 3.6] [Reference Citation Analysis]
67 Tekpli X, Holme JA, Sergent O, Lagadic-gossmann D. Role for membrane remodeling in cell death: Implication for health and disease. Toxicology 2013;304:141-57. [DOI: 10.1016/j.tox.2012.12.014] [Cited by in Crossref: 45] [Cited by in F6Publishing: 43] [Article Influence: 5.0] [Reference Citation Analysis]
68 Ernfors P. Nuclear factor-kappaB to the rescue of cytokine-induced neuronal survival. J Cell Biol 2000;148:223-5. [PMID: 10648553 DOI: 10.1083/jcb.148.2.223] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 0.5] [Reference Citation Analysis]
69 Sarkar FH, Li Y. Indole-3-carbinol and prostate cancer. J Nutr. 2004;134:3493S-3498S. [PMID: 15570059 DOI: 10.1093/jn/134.12.3493s] [Cited by in Crossref: 89] [Cited by in F6Publishing: 30] [Article Influence: 5.2] [Reference Citation Analysis]
70 Heussler VT, Küenzi P, Rottenberg S. Inhibition of apoptosis by intracellular protozoan parasites. Int J Parasitol 2001;31:1166-76. [PMID: 11563357 DOI: 10.1016/s0020-7519(01)00271-5] [Cited by in Crossref: 116] [Cited by in F6Publishing: 46] [Article Influence: 5.8] [Reference Citation Analysis]
71 Sée V, Rajala NK, Spiller DG, White MR. Calcium-dependent regulation of the cell cycle via a novel MAPK--NF-kappaB pathway in Swiss 3T3 cells. J Cell Biol 2004;166:661-72. [PMID: 15326199 DOI: 10.1083/jcb.200402136] [Cited by in Crossref: 41] [Cited by in F6Publishing: 40] [Article Influence: 2.3] [Reference Citation Analysis]
72 Li S, Wang L, Berman MA, Zhang Y, Dorf ME. RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling. Mol Cell 2006;24:497-509. [PMID: 17188031 DOI: 10.1016/j.molcel.2006.10.015] [Cited by in Crossref: 101] [Cited by in F6Publishing: 103] [Article Influence: 6.7] [Reference Citation Analysis]
73 Fan S, Gao M, Meng Q, Laterra JJ, Symons MH, Coniglio S, Pestell RG, Goldberg ID, Rosen EM. Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection. Oncogene. 2005;24:1749-1766. [PMID: 15688034 DOI: 10.1038/sj.onc.1208327] [Cited by in Crossref: 87] [Cited by in F6Publishing: 85] [Article Influence: 5.1] [Reference Citation Analysis]
74 Kang DW, Min do S. Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFkappaB signaling pathway and enhances invasion of breast cancer cells. Cancer Lett 2010;294:125-33. [PMID: 20188462 DOI: 10.1016/j.canlet.2010.01.031] [Cited by in Crossref: 29] [Cited by in F6Publishing: 28] [Article Influence: 2.4] [Reference Citation Analysis]
75 Zhu WZ, Zheng M, Koch WJ, Lefkowitz RJ, Kobilka BK, Xiao RP. Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes. Proc Natl Acad Sci U S A 2001;98:1607-12. [PMID: 11171998 DOI: 10.1073/pnas.98.4.1607] [Cited by in Crossref: 327] [Cited by in F6Publishing: 299] [Article Influence: 15.6] [Reference Citation Analysis]
76 Kong J, Diao Z, Deng X. Inhibition of IGF receptor signaling and hepatoma cell growth by an antibody to ligand oligopeptide of receptor. Growth Factors 2009;26:35-43. [DOI: 10.1080/08977190801987315] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
77 Madge LA, Pober JS. A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells. J Biol Chem. 2000;275:15458-15465. [PMID: 10748004 DOI: 10.1074/jbc.m001237200] [Cited by in Crossref: 161] [Cited by in F6Publishing: 40] [Article Influence: 7.3] [Reference Citation Analysis]
78 Sonoda Y, Yamamoto D, Sakurai S, Hasegawa M, Aizu-yokota E, Momoi T, Kasahara T. FTY720, a Novel Immunosuppressive Agent, Induces Apoptosis in Human Glioma Cells. Biochemical and Biophysical Research Communications 2001;281:282-8. [DOI: 10.1006/bbrc.2001.4352] [Cited by in Crossref: 50] [Cited by in F6Publishing: 43] [Article Influence: 2.4] [Reference Citation Analysis]
79 Galetic I, Maira S, Andjelkovic M, Hemmings BA. Negative Regulation of ERK and Elk by Protein Kinase B Modulates c-fos Transcription. Journal of Biological Chemistry 2003;278:4416-23. [DOI: 10.1074/jbc.m210578200] [Cited by in Crossref: 29] [Cited by in F6Publishing: 12] [Article Influence: 1.5] [Reference Citation Analysis]
80 Liang J, Lu F, Li B, Liu L, Zeng G, Zhou Q, Chen L. IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function. Cell Cycle 2019;18:3300-12. [PMID: 31594449 DOI: 10.1080/15384101.2019.1674053] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
81 Cabezas R, Vega-vela NE, González-sanmiguel J, González J, Esquinas P, Echeverria V, Barreto GE. PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult. Mol Neurobiol 2018;55:3085-95. [DOI: 10.1007/s12035-017-0567-6] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 4.8] [Reference Citation Analysis]
82 Wang H, Zheng Z, Han W, Yuan Y, Li Y, Zhou K, Wang Q, Xie L, Xu K, Zhang H, Xu H, Wu Y, Xiao J. Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule. Oxid Med Cell Longev 2020;2020:9741369. [PMID: 31998447 DOI: 10.1155/2020/9741369] [Cited by in Crossref: 6] [Cited by in F6Publishing: 8] [Article Influence: 3.0] [Reference Citation Analysis]
83 Zhang Y, Zhang R, Ni H. Eriodictyol exerts potent anticancer activity against A549 human lung cancer cell line by inducing mitochondrial-mediated apoptosis, G2/M cell cycle arrest and inhibition of m-TOR/PI3K/Akt signalling pathway. Arch Med Sci 2020;16:446-52. [PMID: 32190156 DOI: 10.5114/aoms.2019.85152] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 3.3] [Reference Citation Analysis]
84 Martínez-López N, Varela-Rey M, Fernández-Ramos D, Woodhoo A, Vázquez-Chantada M, Embade N, Espinosa-Hevia L, Bustamante FJ, Parada LA, Rodriguez MS, Lu SC, Mato JM, Martínez-Chantar ML. Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis. Hepatology 2010;52:1621-31. [PMID: 20815019 DOI: 10.1002/hep.23860] [Cited by in Crossref: 46] [Cited by in F6Publishing: 48] [Article Influence: 3.8] [Reference Citation Analysis]
85 Meng Y, Wang W, Kang J, Wang X, Sun L. Role of the PI3K/AKT signalling pathway in apoptotic cell death in the cerebral cortex of streptozotocin-induced diabetic rats. Exp Ther Med 2017;13:2417-22. [PMID: 28565857 DOI: 10.3892/etm.2017.4259] [Cited by in Crossref: 17] [Cited by in F6Publishing: 18] [Article Influence: 3.4] [Reference Citation Analysis]
86 Tak PP, Firestein GS. NF-kappaB: a key role in inflammatory diseases. J Clin Invest. 2001;107:7-11. [PMID: 11134171 DOI: 10.1172/jci11830] [Cited by in Crossref: 2535] [Cited by in F6Publishing: 1048] [Article Influence: 120.7] [Reference Citation Analysis]
87 Kumari S, Liu X, Nguyen T, Zhang X, D'Mello SR. Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons. Brain Res Mol Brain Res 2001;96:157-62. [PMID: 11731021 DOI: 10.1016/s0006-8993(01)03045-1] [Cited by in Crossref: 28] [Cited by in F6Publishing: 4] [Article Influence: 1.4] [Reference Citation Analysis]
88 White M, Mccubrey J. Suppression of apoptosis: role in cell growth and neoplasia. Leukemia 2001;15:1011-21. [DOI: 10.1038/sj.leu.2402143] [Cited by in Crossref: 47] [Cited by in F6Publishing: 39] [Article Influence: 2.2] [Reference Citation Analysis]
89 Koeberle PD, Bähr M. Growth and guidance cues for regenerating axons: where have they gone? J Neurobiol 2004;59:162-80. [PMID: 15007834 DOI: 10.1002/neu.10345] [Cited by in Crossref: 56] [Cited by in F6Publishing: 59] [Article Influence: 3.1] [Reference Citation Analysis]
90 Neufeld TP. Body building: regulation of shape and size by PI3K/TOR signaling during development. Mech Dev 2003;120:1283-96. [PMID: 14623438 DOI: 10.1016/j.mod.2003.07.003] [Cited by in Crossref: 35] [Cited by in F6Publishing: 37] [Article Influence: 1.9] [Reference Citation Analysis]
91 Kassam S, Montoto S. Oncologic, Endocrine & Metabolic Emerging drugs in B-cell non-Hodgkin's lymphoma. Expert Opinion on Emerging Drugs 2008;13:323-43. [DOI: 10.1517/14728214.13.2.323] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
92 Lee CP, Colombo JS, Ayre WN, Sloan AJ, Waddington RJ. Elucidating the cellular actions of demineralised dentine matrix extract on a clonal dental pulp stem cell population in orchestrating dental tissue repair. J Tissue Eng 2015;6:2041731415586318. [PMID: 26019808 DOI: 10.1177/2041731415586318] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 2.9] [Reference Citation Analysis]
93 Gordon FK, Vallaster CS, Westerling T, Iyer LK, Brown M, Schnitzler GR. Research resource: Aorta- and liver-specific ERα-binding patterns and gene regulation by estrogen. Mol Endocrinol 2014;28:1337-51. [PMID: 24992180 DOI: 10.1210/me.2013-1395] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 2.0] [Reference Citation Analysis]
94 Lee KS, Park SJ, Kim SR, Min KH, Jin SM, Lee HK, Lee YC. Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma. J Immunol 2006;177:5248-57. [PMID: 17015710 DOI: 10.4049/jimmunol.177.8.5248] [Cited by in Crossref: 56] [Cited by in F6Publishing: 54] [Article Influence: 3.7] [Reference Citation Analysis]
95 Tramontano AF, Muniyappa R, Black AD, Blendea MC, Cohen I, Deng L, Sowers JR, Cutaia MV, El-sherif N. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochemical and Biophysical Research Communications 2003;308:990-4. [DOI: 10.1016/s0006-291x(03)01503-1] [Cited by in Crossref: 173] [Cited by in F6Publishing: 41] [Article Influence: 9.1] [Reference Citation Analysis]
96 Scholle F, Bendt KM, Raab-Traub N. Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt. J Virol. 2000;74:10681-10689. [PMID: 11044112 DOI: 10.1128/JVI.74.22.10681-10689.2000] [Cited by in Crossref: 197] [Cited by in F6Publishing: 109] [Article Influence: 9.0] [Reference Citation Analysis]
97 Paoli P, Giannoni E, Chiarugi P. Anoikis molecular pathways and its role in cancer progression. Biochim Biophys Acta. 2013;1833:3481-3498. [PMID: 23830918 DOI: 10.1016/j.bbamcr.2013.06.026] [Cited by in Crossref: 493] [Cited by in F6Publishing: 458] [Article Influence: 54.8] [Reference Citation Analysis]
98 Johnson RA, Wang X, Ma XL, Huong SM, Huang ES. Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: inhibition of PI3-K activity inhibits viral replication and virus-induced signaling. J Virol. 2001;75:6022-6032. [PMID: 11390604 DOI: 10.1128/jvi.75.13.6022-6032.2001] [Cited by in Crossref: 171] [Cited by in F6Publishing: 95] [Article Influence: 8.1] [Reference Citation Analysis]
99 Kwon O, Kim KA, He L, Jung M, Jeong SJ, Ahn JS, Kim BY. Complex formation of p65/RelA with nuclear Akt1 for enhanced transcriptional activation of NF-kappaB. Biochem Biophys Res Commun 2008;365:771-6. [PMID: 18035048 DOI: 10.1016/j.bbrc.2007.11.037] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
100 Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 2001;20:1287-99. [PMID: 11313873 DOI: 10.1038/sj.onc.1204257] [Cited by in Crossref: 186] [Cited by in F6Publishing: 170] [Article Influence: 8.9] [Reference Citation Analysis]
101 Bouraoui Y, Ben Rais N, Culig Z, Oueslati R. Involvement of interleukin-1β mediated nuclear factor κB signalling pathways to down-regulate prostate-specific antigen and cell proliferation in LNCaP prostate cancer cells. Cell Biol Int 2012;36:449-54. [PMID: 22103356 DOI: 10.1042/CBI20100922] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
102 Zhan XK, Li JL, Zhang S, Xing PY, Xia MF. Betulinic acid exerts potent antitumor effects on paclitaxel-resistant human lung carcinoma cells (H460) via G2/M phase cell cycle arrest and induction of mitochondrial apoptosis. Oncol Lett 2018;16:3628-34. [PMID: 30127971 DOI: 10.3892/ol.2018.9097] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 2.3] [Reference Citation Analysis]
103 Oishi H, Takano K, Tomita K, Takebe M, Yokoo H, Yamazaki M, Hattori Y. Olprinone and colforsin daropate alleviate septic lung inflammation and apoptosis through CREB-independent activation of the Akt pathway. Am J Physiol Lung Cell Mol Physiol 2012;303:L130-40. [PMID: 22610350 DOI: 10.1152/ajplung.00363.2011] [Cited by in Crossref: 33] [Cited by in F6Publishing: 33] [Article Influence: 3.3] [Reference Citation Analysis]
104 Maehara K, Oh‐hashi K, Isobe K. Early growth responsive‐1‐dependent manganese superoxide dismutase gene transcription mediated by platelet‐derived growth factor. FASEB j 2001;15:2025-6. [DOI: 10.1096/fj.00-0909fje] [Cited by in Crossref: 30] [Cited by in F6Publishing: 27] [Article Influence: 1.4] [Reference Citation Analysis]
105 Martin AG, San-Antonio B, Fresno M. Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha. J Biol Chem 2001;276:15840-9. [PMID: 11278885 DOI: 10.1074/jbc.M011313200] [Cited by in Crossref: 73] [Cited by in F6Publishing: 28] [Article Influence: 3.5] [Reference Citation Analysis]
106 Peng Q, Li K, Wang N, Li Q, Asgari E, Lu B, Woodruff TM, Sacks SH, Zhou W. Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol. 2009;183:6058-6068. [PMID: 19864610 DOI: 10.4049/jimmunol.0804186] [Cited by in Crossref: 85] [Cited by in F6Publishing: 89] [Article Influence: 6.5] [Reference Citation Analysis]
107 Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem 2006;281:10715-26. [PMID: 16484225 DOI: 10.1074/jbc.M511343200] [Cited by in Crossref: 123] [Cited by in F6Publishing: 69] [Article Influence: 7.7] [Reference Citation Analysis]
108 Youn BS, Kim YJ, Mantel C, Yu KY, Broxmeyer HE. Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction. Blood 2001;98:925-33. [PMID: 11493434 DOI: 10.1182/blood.v98.4.925] [Cited by in Crossref: 43] [Cited by in F6Publishing: 17] [Article Influence: 2.0] [Reference Citation Analysis]
109 Chen L, Xiong YQ, Xu J, Wang JP, Meng ZL, Hong YQ. Juglanin inhibits lung cancer by regulation of apoptosis, ROS and autophagy induction. Oncotarget 2017;8:93878-98. [PMID: 29212196 DOI: 10.18632/oncotarget.21317] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 3.4] [Reference Citation Analysis]
110 Yang L, Wang Y, Mao H, Fleig S, Omenetti A, Brown KD, Sicklick JK, Li YX, Diehl AM. Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. J Hepatol. 2008;48:98-106. [PMID: 18022723 DOI: 10.1016/j.jhep.2007.07.032] [Cited by in Crossref: 147] [Cited by in F6Publishing: 142] [Article Influence: 9.8] [Reference Citation Analysis]
111 Yamane K, Ihn H, Tamaki K. Epidermal growth factor up-regulates expression of transforming growth factor ? receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblasts. Arthritis & Rheumatism 2003;48:1652-66. [DOI: 10.1002/art.11029] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 1.2] [Reference Citation Analysis]
112 Hunter RB, Stevenson E, Koncarevic A, Mitchell-Felton H, Essig DA, Kandarian SC. Activation of an alternative NF-kappaB pathway in skeletal muscle during disuse atrophy. FASEB J. 2002;16:529-538. [PMID: 11919155 DOI: 10.1096/fj.01-0866com] [Cited by in Crossref: 204] [Cited by in F6Publishing: 191] [Article Influence: 10.2] [Reference Citation Analysis]
113 Wang Q, Kim S, Wang X, Evers B. Activation of NF-κB Binding in HT-29 Colon Cancer Cells by Inhibition of Phosphatidylinositol 3-Kinase. Biochemical and Biophysical Research Communications 2000;273:853-8. [DOI: 10.1006/bbrc.2000.3034] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 0.7] [Reference Citation Analysis]
114 Kuo AH, Stoica GE, Riegel AT, Wellstein A. Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase. Oncogene 2007;26:859-69. [PMID: 16878150 DOI: 10.1038/sj.onc.1209840] [Cited by in Crossref: 33] [Cited by in F6Publishing: 33] [Article Influence: 2.1] [Reference Citation Analysis]
115 El-dydamony NM, Abdelnaby RM, Abdelhady R, Ali O, Fahmy MI, R. Fakhr Eldeen R, Helwa AA. Pyrimidine-5-carbonitrile based potential anticancer agents as apoptosis inducers through PI3K/AKT axis inhibition in leukaemia K562. Journal of Enzyme Inhibition and Medicinal Chemistry 2022;37:895-911. [DOI: 10.1080/14756366.2022.2051022] [Reference Citation Analysis]
116 Matsumoto M, Ogawa W, Hino Y, Furukawa K, Ono Y, Takahashi M, Ohba M, Kuroki T, Kasuga M. Inhibition of Insulin-induced Activation of Akt by a Kinase-deficient Mutant of the ε Isozyme of Protein Kinase C. Journal of Biological Chemistry 2001;276:14400-6. [DOI: 10.1074/jbc.m011093200] [Cited by in Crossref: 27] [Cited by in F6Publishing: 14] [Article Influence: 1.3] [Reference Citation Analysis]
117 Singh S, Srivastava SK, Bhardwaj A, Owen LB, Singh AP. CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy. Br J Cancer. 2010;103:1671-1679. [PMID: 21045835 DOI: 10.1038/sj.bjc.6605968] [Cited by in Crossref: 128] [Cited by in F6Publishing: 153] [Article Influence: 10.7] [Reference Citation Analysis]
118 Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A. IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nat Commun 2011;2:318. [PMID: 21587235 DOI: 10.1038/ncomms1317] [Cited by in Crossref: 24] [Cited by in F6Publishing: 26] [Article Influence: 2.2] [Reference Citation Analysis]
119 Harrigan MR. Angiogenic Factors in the Central Nervous System. Neurosurgery 2003;53:639-61. [DOI: 10.1227/01.neu.0000079575.09923.59] [Cited by in Crossref: 67] [Cited by in F6Publishing: 20] [Article Influence: 3.5] [Reference Citation Analysis]
120 Halvorsen EM, Dennis J, Keeney PM, Sturgill TW, Tuttle JB, Bennett JP. Methylpyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells. Brain Research 2002;952:98-110. [DOI: 10.1016/s0006-8993(02)03216-x] [Cited by in Crossref: 45] [Cited by in F6Publishing: 10] [Article Influence: 2.3] [Reference Citation Analysis]
121 Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC. The emerging role of the PI3-K-Akt pathway in prostate cancer progression. Prostate Cancer Prostatic Dis 2005;8:108-18. [PMID: 15724144 DOI: 10.1038/sj.pcan.4500776] [Cited by in Crossref: 90] [Cited by in F6Publishing: 82] [Article Influence: 5.3] [Reference Citation Analysis]
122 Gustin JA, Maehama T, Dixon JE, Donner DB. The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity. J Biol Chem 2001;276:27740-4. [PMID: 11356844 DOI: 10.1074/jbc.M102559200] [Cited by in Crossref: 83] [Cited by in F6Publishing: 27] [Article Influence: 4.0] [Reference Citation Analysis]
123 Yano S, Morioka M, Fukunaga K, Kawano T, Hara T, Kai Y, Hamada J, Miyamoto E, Ushio Y. Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus. J Cereb Blood Flow Metab 2001;21:351-60. [PMID: 11323521 DOI: 10.1097/00004647-200104000-00004] [Cited by in Crossref: 180] [Cited by in F6Publishing: 178] [Article Influence: 8.6] [Reference Citation Analysis]
124 Simakajornboon N, Szerlip NJ, Gozal E, Anonetapipat JW, Gozal D. In vivo PDGF beta receptor activation in the dorsocaudal brainstem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD. Brain Res 2001;895:111-8. [PMID: 11259767 DOI: 10.1016/s0006-8993(01)02054-6] [Cited by in Crossref: 28] [Cited by in F6Publishing: 7] [Article Influence: 1.3] [Reference Citation Analysis]
125 Arafa el-SA, Zhu Q, Barakat BM, Wani G, Zhao Q, El-Mahdy MA, Wani AA. Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway. Cancer Res 2009;69:8910-7. [PMID: 19903849 DOI: 10.1158/0008-5472.CAN-09-1543] [Cited by in Crossref: 84] [Cited by in F6Publishing: 37] [Article Influence: 6.5] [Reference Citation Analysis]
126 Yan J, Li M, Threadgill MD, Wang Y, Fu W. Decreasing P-selectin and ICAM-1 via activating Akt: a possible mechanism by which PARG inhibits adhesion of mouse colorectal carcinoma CT26 cells to platelets. Cancer Gene Ther 2013;20:487-92. [PMID: 23949281 DOI: 10.1038/cgt.2013.44] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
127 Thomas KW, Monick MM, Staber JM, Yarovinsky T, Carter AB, Hunninghake GW. Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway. J Biol Chem 2002;277:492-501. [PMID: 11687577 DOI: 10.1074/jbc.M108107200] [Cited by in Crossref: 104] [Cited by in F6Publishing: 57] [Article Influence: 5.0] [Reference Citation Analysis]
128 Ahmad A, Wang Z, Kong D, Ali R, Ali S, Banerjee S, Sarkar FH. Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways. Breast Cancer Res Treat. 2011;126:15-25. [PMID: 20379844 DOI: 10.1007/s10549-010-0883-2] [Cited by in Crossref: 45] [Cited by in F6Publishing: 44] [Article Influence: 3.8] [Reference Citation Analysis]
129 Israely E, Ginsberg M, Nolan D, Ding BS, James D, Elemento O, Rafii S, Rabbany SY. Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells. Stem Cells 2014;32:177-90. [PMID: 23963623 DOI: 10.1002/stem.1521] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 2.3] [Reference Citation Analysis]
130 Juuti-Uusitalo KM, Kaukinen K, Mäki M, Tuimala J, Kainulainen H. Gene expression in TGFbeta-induced epithelial cell differentiation in a three-dimensional intestinal epithelial cell differentiation model. BMC Genomics 2006;7:279. [PMID: 17074098 DOI: 10.1186/1471-2164-7-279] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 0.6] [Reference Citation Analysis]
131 Cai Q, Lanting L, Natarajan R. Interaction of monocytes with vascular smooth muscle cells regulates monocyte survival and differentiation through distinct pathways. Arterioscler Thromb Vasc Biol 2004;24:2263-70. [PMID: 15458980 DOI: 10.1161/01.ATV.0000146552.16943.5e] [Cited by in Crossref: 47] [Cited by in F6Publishing: 24] [Article Influence: 2.6] [Reference Citation Analysis]
132 Kociok N, Radetzky S, Krohne TU, Gavranic C, Liang Y, Semkova I, Joussen AM. ICAM-1 depletion does not alter retinal vascular development in a model of oxygen-mediated neovascularization. Exp Eye Res 2009;89:503-10. [PMID: 19482023 DOI: 10.1016/j.exer.2009.05.005] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 0.7] [Reference Citation Analysis]
133 Meng F, Henson R, Patel T. Chemotherapeutic stress selectively activates NF-κB-dependent AKT and VEGF expression in liver cancer-derived endothelial cells. American Journal of Physiology-Cell Physiology 2007;293:C749-60. [DOI: 10.1152/ajpcell.00537.2006] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 0.9] [Reference Citation Analysis]
134 Wang HJ, Cao JP, Yu JK, Zhang LC, Jiang ZJ, Gao DS. Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-kappaB signaling pathway. Eur J Pharmacol 2008;595:7-12. [PMID: 18703048 DOI: 10.1016/j.ejphar.2008.07.044] [Cited by in Crossref: 18] [Cited by in F6Publishing: 19] [Article Influence: 1.3] [Reference Citation Analysis]
135 Saida L, Tulasi CDSLN, Narasu ML. Evaluation of chemo-preventive efficacy of Ficus religiosa latex extract by flow cytometry analysis and gene expression studies performed by RT-PCR in various cell lines. Futur J Pharm Sci 2021;7. [DOI: 10.1186/s43094-021-00182-x] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
136 Wickenden JA, Watson CJ. Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts. Breast Cancer Res 2010;12:202. [PMID: 20398329 DOI: 10.1186/bcr2558] [Cited by in Crossref: 65] [Cited by in F6Publishing: 61] [Article Influence: 5.4] [Reference Citation Analysis]
137 Tsuchiya K, Banks AS, Liang CP, Tabas I, Tall AR, Accili D. Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis. Arterioscler Thromb Vasc Biol 2011;31:2920-8. [PMID: 21940942 DOI: 10.1161/ATVBAHA.110.219477] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 1.2] [Reference Citation Analysis]
138 Zhou J, Eksioglu EA, Fortenbery NR, Chen X, Wang H, Epling-Burnette PK, Djeu JY, Wei S. Bone marrow mononuclear cells up-regulate toll-like receptor expression and produce inflammatory mediators in response to cigarette smoke extract. PLoS One. 2011;6:e21173. [PMID: 21738617 DOI: 10.1371/journal.pone.0021173] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 1.3] [Reference Citation Analysis]
139 Hsieh H, Wang H, Wu C, Tung W, Yang C. Lipoteichoic Acid Induces Matrix Metalloproteinase-9 Expression via Transactivation of PDGF Receptors and NF-κB Activation in Rat Brain Astrocytes. Neurotox Res 2010;17:344-59. [DOI: 10.1007/s12640-009-9111-4] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 1.7] [Reference Citation Analysis]
140 Giri S, Rattan R, Singh AK, Singh I. The 15-Deoxy-δ12,14-Prostaglandin J 2 Inhibits the Inflammatory Response in Primary Rat Astrocytes via Down-Regulating Multiple Steps in Phosphatidylinositol 3-Kinase-Akt-NF-κB-p300 Pathway Independent of Peroxisome Proliferator-Activated Receptor γ. J Immunol 2004;173:5196-208. [DOI: 10.4049/jimmunol.173.8.5196] [Cited by in Crossref: 108] [Cited by in F6Publishing: 108] [Article Influence: 6.0] [Reference Citation Analysis]
141 Gao Z, Sasaoka T, Fujimori T, Oya T, Ishii Y, Sabit H, Kawaguchi M, Kurotaki Y, Naito M, Wada T. Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing. J Biol Chem. 2005;280:9375-9389. [PMID: 15590688 DOI: 10.1074/jbc.m413081200] [Cited by in Crossref: 69] [Cited by in F6Publishing: 32] [Article Influence: 3.8] [Reference Citation Analysis]
142 Soubannier V, Stifani S. NF-κB Signalling in Glioblastoma. Biomedicines 2017;5:E29. [PMID: 28598356 DOI: 10.3390/biomedicines5020029] [Cited by in Crossref: 28] [Cited by in F6Publishing: 23] [Article Influence: 5.6] [Reference Citation Analysis]
143 Solary E, Droin N, Sordet O, Rebe C, Filomenko R, Wotawa A, Plenchette S, Ducoroy P. CELL DEATH PATHWAYS AS TARGETS FOR ANTICANCER DRUGS. Anticancer Drug Development. Elsevier; 2002. pp. 55-76. [DOI: 10.1016/b978-012072651-6/50005-x] [Cited by in Crossref: 2] [Article Influence: 0.1] [Reference Citation Analysis]
144 Kwon Y, Min J, Kim K, Lee D, Billiar TR, Kim Y. Sphingosine 1-Phosphate Protects Human Umbilical Vein Endothelial Cells from Serum-deprived Apoptosis by Nitric Oxide Production. Journal of Biological Chemistry 2001;276:10627-33. [DOI: 10.1074/jbc.m011449200] [Cited by in Crossref: 154] [Cited by in F6Publishing: 39] [Article Influence: 7.3] [Reference Citation Analysis]
145 Lin F, Ren XD, Pan Z, Macri L, Zong WX, Tonnesen MG, Rafailovich M, Bar-Sagi D, Clark RA. Fibronectin growth factor-binding domains are required for fibroblast survival. J Invest Dermatol 2011;131:84-98. [PMID: 20811396 DOI: 10.1038/jid.2010.253] [Cited by in Crossref: 55] [Cited by in F6Publishing: 51] [Article Influence: 4.6] [Reference Citation Analysis]
146 Gennebäck N, Hellman U, Malm L, Larsson G, Ronquist G, Waldenström A, Mörner S. Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Journal of Extracellular Vesicles 2013;2:20167. [DOI: 10.3402/jev.v2i0.20167] [Cited by in Crossref: 47] [Cited by in F6Publishing: 45] [Article Influence: 5.2] [Reference Citation Analysis]
147 Zha H, Raffeld M, Charboneau L, Pittaluga S, Kwak LW, Petricoin E, Liotta LA, Jaffe ES. Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray. Lab Invest 2004;84:235-44. [DOI: 10.1038/labinvest.3700051] [Cited by in Crossref: 72] [Cited by in F6Publishing: 56] [Article Influence: 4.0] [Reference Citation Analysis]
148 Israël A. The IKK complex: an integrator of all signals that activate NF-kappaB? Trends Cell Biol. 2000;10:129-133. [PMID: 10740266 DOI: 10.1016/s0962-8924(00)01729-3] [Cited by in Crossref: 294] [Cited by in F6Publishing: 94] [Article Influence: 13.4] [Reference Citation Analysis]
149 Spiegelman VS, Stavropoulos P, Latres E, Pagano M, Ronai Z, Slaga TJ, Fuchs SY. Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB. Journal of Biological Chemistry 2001;276:27152-8. [DOI: 10.1074/jbc.m100031200] [Cited by in Crossref: 49] [Cited by in F6Publishing: 21] [Article Influence: 2.3] [Reference Citation Analysis]
150 Hyckel P, Berndt A, Schleier P, Clement JH, Beensen V, Peters H, Kosmehl H. Cherubism – new hypotheses on pathogenesis and therapeutic consequences. Journal of Cranio-Maxillofacial Surgery 2005;33:61-8. [DOI: 10.1016/j.jcms.2004.07.006] [Cited by in Crossref: 64] [Cited by in F6Publishing: 57] [Article Influence: 3.8] [Reference Citation Analysis]
151 Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res 2004;94:884-91. [PMID: 14988230 DOI: 10.1161/01.RES.0000124394.01180.BE] [Cited by in Crossref: 159] [Cited by in F6Publishing: 83] [Article Influence: 8.8] [Reference Citation Analysis]
152 Scheid MP, Woodgett JR. PKB/AKT: functional insights from genetic models. Nat Rev Mol Cell Biol. 2001;2:760-768. [PMID: 11584303 DOI: 10.1038/35096067] [Cited by in Crossref: 434] [Cited by in F6Publishing: 435] [Article Influence: 20.7] [Reference Citation Analysis]
153 Dhandapani KM, Wade FM, Wakade C, Mahesh VB, Brann DW. Neuroprotection by stem cell factor in rat cortical neurons involves AKT and NFκB: Akt/NFκB regulates SCF-mediated survival. Journal of Neurochemistry 2005;95:9-19. [DOI: 10.1111/j.1471-4159.2005.03319.x] [Cited by in Crossref: 74] [Cited by in F6Publishing: 70] [Article Influence: 4.4] [Reference Citation Analysis]
154 Macleod K. Tumor suppressor genes. Current Opinion in Genetics & Development 2000;10:81-93. [DOI: 10.1016/s0959-437x(99)00041-6] [Cited by in Crossref: 103] [Cited by in F6Publishing: 19] [Article Influence: 4.7] [Reference Citation Analysis]
155 Steele-Mortimer O, Knodler LA, Marcus SL, Scheid MP, Goh B, Pfeifer CG, Duronio V, Finlay BB. Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD. J Biol Chem 2000;275:37718-24. [PMID: 10978351 DOI: 10.1074/jbc.M008187200] [Cited by in Crossref: 151] [Cited by in F6Publishing: 68] [Article Influence: 7.2] [Reference Citation Analysis]
156 Li J, Zhang D, Stoner GD, Huang C. Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes. Mol Carcinog 2008;47:286-94. [PMID: 18085529 DOI: 10.1002/mc.20377] [Cited by in Crossref: 28] [Cited by in F6Publishing: 22] [Article Influence: 2.0] [Reference Citation Analysis]
157 Castellino RC, Durden DL. Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors. Nat Clin Pract Neurol 2007;3:682-93. [PMID: 18046441 DOI: 10.1038/ncpneuro0661] [Cited by in Crossref: 79] [Cited by in F6Publishing: 73] [Article Influence: 5.6] [Reference Citation Analysis]
158 Wiles TJ, Dhakal BK, Eto DS, Mulvey MA. Inactivation of host Akt/protein kinase B signaling by bacterial pore-forming toxins. Mol Biol Cell 2008;19:1427-38. [PMID: 18234841 DOI: 10.1091/mbc.e07-07-0638] [Cited by in Crossref: 66] [Cited by in F6Publishing: 48] [Article Influence: 4.7] [Reference Citation Analysis]
159 Kim JH, Lee G, Cho YL, Kim CK, Han S, Lee H, Choi JS, Choe J, Won MH, Kwon YG, Ha KS, Kim YM. Desmethylanhydroicaritin inhibits NF-kappaB-regulated inflammatory gene expression by modulating the redox-sensitive PI3K/PTEN/Akt pathway. Eur J Pharmacol 2009;602:422-31. [PMID: 19027002 DOI: 10.1016/j.ejphar.2008.10.062] [Cited by in Crossref: 29] [Cited by in F6Publishing: 27] [Article Influence: 2.1] [Reference Citation Analysis]
160 Nebigil CG, Etienne N, Messaddeq N, Maroteaux L. Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT2B receptor signaling. FASEB J 2003;17:1373-5. [PMID: 12738797 DOI: 10.1096/fj.02-1122fje] [Cited by in Crossref: 105] [Cited by in F6Publishing: 91] [Article Influence: 5.5] [Reference Citation Analysis]
161 Yum HK, Arcaroli J, Kupfner J, Shenkar R, Penninger JM, Sasaki T, Yang KY, Park JS, Abraham E. Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. J Immunol. 2001;167:6601-6608. [PMID: 11714830 DOI: 10.4049/jimmunol.167.11.6601] [Cited by in Crossref: 154] [Cited by in F6Publishing: 151] [Article Influence: 7.7] [Reference Citation Analysis]
162 Goel A, Dispenzieri A, Witzig TE, Russell SJ. Enhancing the therapeutic index of radiation in multiple myeloma. Drug Discovery Today: Disease Mechanisms 2006;3:515-22. [DOI: 10.1016/j.ddmec.2006.11.012] [Cited by in Crossref: 5] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
163 Janjetovic K, Vucicevic L, Misirkic M, Vilimanovich U, Tovilovic G, Zogovic N, Nikolic Z, Jovanovic S, Bumbasirevic V, Trajkovic V, Harhaji-Trajkovic L. Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of Akt. Eur J Pharmacol 2011;651:41-50. [PMID: 21114978 DOI: 10.1016/j.ejphar.2010.11.005] [Cited by in Crossref: 70] [Cited by in F6Publishing: 66] [Article Influence: 5.8] [Reference Citation Analysis]
164 Hou D, Kumamoto T. Flavonoids as Protein Kinase Inhibitors for Cancer Chemoprevention: Direct Binding and Molecular Modeling. Antioxidants & Redox Signaling 2010;13:691-719. [DOI: 10.1089/ars.2009.2816] [Cited by in Crossref: 125] [Cited by in F6Publishing: 107] [Article Influence: 10.4] [Reference Citation Analysis]
165 Wang X, Chen L, Maures TJ, Herrington J, Carter-Su C. SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells. J Biol Chem. 2004;279:133-141. [PMID: 14565960 DOI: 10.1074/jbc.m310040200] [Cited by in Crossref: 22] [Cited by in F6Publishing: 10] [Article Influence: 1.2] [Reference Citation Analysis]
166 Bresin A, Callegari E, D'Abundo L, Cattani C, Bassi C, Zagatti B, Narducci MG, Caprini E, Pekarsky Y, Croce CM, Sabbioni S, Russo G, Negrini M. miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model. Oncotarget 2015;6:19807-18. [PMID: 26090867 DOI: 10.18632/oncotarget.4415] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 3.5] [Reference Citation Analysis]
167 Daily D, Vlamis-Gardikas A, Offen D, Mittelman L, Melamed E, Holmgren A, Barzilai A. Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. J Biol Chem. 2001;276:21618-21626. [PMID: 11290748 DOI: 10.1074/jbc.M101400200] [Cited by in Crossref: 62] [Cited by in F6Publishing: 18] [Article Influence: 3.0] [Reference Citation Analysis]
168 Makarov SS. NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res 2001;3:200-6. [PMID: 11438035 DOI: 10.1186/ar300] [Cited by in Crossref: 254] [Cited by in F6Publishing: 252] [Article Influence: 12.1] [Reference Citation Analysis]
169 Nakazawa T, Shimura M, Tomita H, Akiyama H, Yoshioka Y, Kudou H, Tamai M. Intrinsic activation of PI3K/Akt signaling pathway and its neuroprotective effect against retinal injury. Curr Eye Res 2003;26:55-63. [PMID: 12789537 DOI: 10.1076/ceyr.26.1.55.14254] [Cited by in Crossref: 54] [Cited by in F6Publishing: 53] [Article Influence: 2.8] [Reference Citation Analysis]
170 Pati S, Cavrois M, Guo HG, Foulke JS Jr, Kim J, Feldman RA, Reitz M. Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis. J Virol 2001;75:8660-73. [PMID: 11507211 DOI: 10.1128/jvi.75.18.8660-8673.2001] [Cited by in Crossref: 131] [Cited by in F6Publishing: 60] [Article Influence: 6.2] [Reference Citation Analysis]
171 Guo S, Wu X, Zheng J, Smith SA, Dong P, Xiao H. Identification of 4'-Demethyltangeretin as a Major Urinary Metabolite of Tangeretin in Mice and Its Anti-inflammatory Activities. J Agric Food Chem 2021;69:4381-91. [PMID: 33787243 DOI: 10.1021/acs.jafc.0c06334] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
172 Sharma SD, Katiyar SK. Leptin deficiency-induced obesity exacerbates ultraviolet B radiation-induced cyclooxygenase-2 expression and cell survival signals in ultraviolet B-irradiated mouse skin. Toxicol Appl Pharmacol 2010;244:328-35. [PMID: 20122948 DOI: 10.1016/j.taap.2010.01.010] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 1.7] [Reference Citation Analysis]
173 Clark J, Freeman J, Donninger H. Loss of RASSF2 Enhances Tumorigencity of Lung Cancer Cells and Confers Resistance to Chemotherapy. Mol Biol Int 2012;2012:705948. [PMID: 22693671 DOI: 10.1155/2012/705948] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 1.1] [Reference Citation Analysis]
174 Barthel A, Ostrakhovitch EA, Walter PL, Kampkötter A, Klotz LO. Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: mechanisms and consequences. Arch Biochem Biophys 2007;463:175-82. [PMID: 17509519 DOI: 10.1016/j.abb.2007.04.015] [Cited by in Crossref: 95] [Cited by in F6Publishing: 86] [Article Influence: 6.3] [Reference Citation Analysis]
175 Maiti D, Bhattacharyya A, Basu J. Lipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem 2001;276:329-33. [PMID: 11020382 DOI: 10.1074/jbc.M002650200] [Cited by in Crossref: 107] [Cited by in F6Publishing: 39] [Article Influence: 5.1] [Reference Citation Analysis]
176 Sugano M, Tsuchida K, Makino N. A protein tyrosine phosphatase inhibitor accelerates angiogenesis in a rat model of hindlimb ischemia. J Cardiovasc Pharmacol 2004;44:460-5. [PMID: 15454854 DOI: 10.1097/01.fjc.0000143275.45289.0a] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 1.1] [Reference Citation Analysis]
177 Troussard AA, Costello P, Yoganathan TN, Kumagai S, Roskelley CD, Dedhar S. The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9). Oncogene. 2000;19:5444-5452. [PMID: 11114721 DOI: 10.1038/sj.onc.1203928] [Cited by in Crossref: 133] [Cited by in F6Publishing: 138] [Article Influence: 6.0] [Reference Citation Analysis]
178 Kang JS, Yoon YD, Han MH, Han SB, Lee K, Lee KH, Park SK, Kim HM. Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways. Mol Pharmacol 2006;69:941-9. [PMID: 16354764 DOI: 10.1124/mol.105.017442] [Cited by in Crossref: 42] [Cited by in F6Publishing: 40] [Article Influence: 2.5] [Reference Citation Analysis]
179 Han DW, Lim HR, Baek HS, Lee MH, Lee SJ, Hyon SH, Park JC. Inhibitory effects of epigallocatechin-3-O-gallate on serum-stimulated rat aortic smooth muscle cells via nuclear factor-kappaB down-modulation. Biochem Biophys Res Commun 2006;345:148-55. [PMID: 16677605 DOI: 10.1016/j.bbrc.2006.04.072] [Cited by in Crossref: 18] [Cited by in F6Publishing: 15] [Article Influence: 1.1] [Reference Citation Analysis]
180 Pal A, Tewari-Singh N, Gu M, Agarwal C, Huang J, Day BJ, White CW, Agarwal R. Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice. Free Radic Biol Med 2009;47:1640-51. [PMID: 19761830 DOI: 10.1016/j.freeradbiomed.2009.09.011] [Cited by in Crossref: 63] [Cited by in F6Publishing: 59] [Article Influence: 4.8] [Reference Citation Analysis]
181 Mantamadiotis T. Towards Targeting PI3K-Dependent Regulation of Gene Expression in Brain Cancer. Cancers (Basel) 2017;9:E60. [PMID: 28556811 DOI: 10.3390/cancers9060060] [Cited by in Crossref: 17] [Cited by in F6Publishing: 15] [Article Influence: 3.4] [Reference Citation Analysis]
182 Kaur G, Balasubramaniam SD, Lee YJ. IGFBP-2 in cervical cancer development. Exp Mol Pathol 2020;113:104362. [PMID: 31870856 DOI: 10.1016/j.yexmp.2019.104362] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
183 Amit S, Ben-Neriah Y. NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach. Semin Cancer Biol 2003;13:15-28. [PMID: 12507553 DOI: 10.1016/s1044-579x(02)00096-2] [Cited by in Crossref: 96] [Cited by in F6Publishing: 35] [Article Influence: 5.1] [Reference Citation Analysis]
184 Attwell S, Roskelley C, Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene. 2000;19:3811-3815. [PMID: 10949937 DOI: 10.1038/sj.onc.1203711] [Cited by in Crossref: 160] [Cited by in F6Publishing: 164] [Article Influence: 7.3] [Reference Citation Analysis]
185 Sun X, Yasuda O, Takemura Y, Kawamoto H, Higuchi M, Baba Y, Katsuya T, Fukuo K, Ogihara T, Rakugi H. Akt activation prevents Apop-1-induced death of cells. Biochemical and Biophysical Research Communications 2008;377:1097-101. [DOI: 10.1016/j.bbrc.2008.10.109] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
186 Hasegawa Y, Morioka M, Hasegawa S, Matsumoto J, Kawano T, Kai Y, Yano S, Fukunaga K, Kuratsu J. Therapeutic Time Window and Dose Dependence of Neuroprotective Effects of Sodium Orthovanadate following Transient Middle Cerebral Artery Occlusion in Rats. J Pharmacol Exp Ther 2006;317:875-81. [DOI: 10.1124/jpet.105.096677] [Cited by in Crossref: 27] [Cited by in F6Publishing: 24] [Article Influence: 1.7] [Reference Citation Analysis]
187 Drosten M, Hilken G, Böckmann M, Rödicker F, Mise N, Cranston AN, Dahmen U, Ponder BA, Pützer BM. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. J Natl Cancer Inst 2004;96:1231-9. [PMID: 15316058 DOI: 10.1093/jnci/djh226] [Cited by in Crossref: 52] [Cited by in F6Publishing: 47] [Article Influence: 2.9] [Reference Citation Analysis]
188 Eda H, Shimada H, Beidler DR, Monahan JB. Proinflammatory cytokines, IL-1β and TNF-α, induce expression of interleukin-34 mRNA via JNK- and p44/42 MAPK-NF-κB pathway but not p38 pathway in osteoblasts. Rheumatol Int 2011;31:1525-30. [DOI: 10.1007/s00296-010-1688-7] [Cited by in Crossref: 65] [Cited by in F6Publishing: 64] [Article Influence: 5.4] [Reference Citation Analysis]
189 Yang JY, Walicki J, Abderrahmani A, Cornu M, Waeber G, Thorens B, Widmann C. Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem 2005;280:32835-42. [PMID: 16046410 DOI: 10.1074/jbc.M504058200] [Cited by in Crossref: 16] [Cited by in F6Publishing: 6] [Article Influence: 0.9] [Reference Citation Analysis]
190 Scupoli MT, Pizzolo G. Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia. Expert Rev Hematol 2012;5:341-8. [PMID: 22780213 DOI: 10.1586/ehm.12.21] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 1.7] [Reference Citation Analysis]
191 He X, Wang Y, Hu H, Zhang Z. In Vitro and in Vivo Antimammary Tumor Activities and Mechanisms of the Apple Total Triterpenoids. J Agric Food Chem 2012;60:9430-6. [DOI: 10.1021/jf3026925] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 1.2] [Reference Citation Analysis]
192 Yang CH, Murti A, Pfeffer SR, Kim JG, Donner DB, Pfeffer LM. Interferon α/β Promotes Cell Survival by Activating Nuclear Factor κB through Phosphatidylinositol 3-Kinase and Akt. Journal of Biological Chemistry 2001;276:13756-61. [DOI: 10.1074/jbc.m011006200] [Cited by in Crossref: 159] [Cited by in F6Publishing: 52] [Article Influence: 7.6] [Reference Citation Analysis]
193 Hua F, Ha T, Ma J, Li Y, Kelley J, Gao X, Browder IW, Kao RL, Williams DL, Li C. Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanism. J Immunol 2007;178:7317-24. [PMID: 17513782 DOI: 10.4049/jimmunol.178.11.7317] [Cited by in Crossref: 114] [Cited by in F6Publishing: 118] [Article Influence: 7.6] [Reference Citation Analysis]
194 Hu HZ, Yang YB, Xu XD, Shen HW, Shu YM, Ren Z, Li XM, Shen HM, Zeng HT. Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line. Acta Pharmacol Sin. 2007;28:1819-1826. [PMID: 17959034 DOI: 10.1111/j.1745-7254.2007.00667.x] [Cited by in Crossref: 59] [Cited by in F6Publishing: 51] [Article Influence: 4.5] [Reference Citation Analysis]
195 Fan H, Tu T, Zhang X, Yang Q, Liu G, Zhang T, Bao Y, Lu Y, Dong Z, Dong J, Zhao P. Sinomenine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress, inflammation and apoptosis in mice. Food Chem Toxicol 2021;159:112759. [PMID: 34883223 DOI: 10.1016/j.fct.2021.112759] [Reference Citation Analysis]
196 Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K. Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development. Sci Rep 2015;5:12841. [PMID: 26269411 DOI: 10.1038/srep12841] [Cited by in Crossref: 25] [Cited by in F6Publishing: 25] [Article Influence: 3.6] [Reference Citation Analysis]
197 Petro JB, Khan WN. Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappaB signaling pathway in B lymphocytes. J Biol Chem 2001;276:1715-9. [PMID: 11042193 DOI: 10.1074/jbc.M009137200] [Cited by in Crossref: 95] [Cited by in F6Publishing: 42] [Article Influence: 4.3] [Reference Citation Analysis]
198 Zhang HS, Cao EH, Qin JF. Homocysteine induces cell cycle G1 arrest in endothelial cells through the PI3K/Akt/FOXO signaling pathway. Pharmacology 2005;74:57-64. [PMID: 15677884 DOI: 10.1159/000083684] [Cited by in Crossref: 20] [Cited by in F6Publishing: 22] [Article Influence: 1.2] [Reference Citation Analysis]
199 Ansari KM, Rundhaug JE, Fischer SM. Multiple signaling pathways are responsible for prostaglandin E2-induced murine keratinocyte proliferation. Mol Cancer Res 2008;6:1003-16. [PMID: 18567804 DOI: 10.1158/1541-7786.MCR-07-2144] [Cited by in Crossref: 58] [Cited by in F6Publishing: 30] [Article Influence: 4.1] [Reference Citation Analysis]
200 Park YH. The nuclear factor-kappa B pathway and response to treatment in breast cancer. Pharmacogenomics 2017;18:1697-709. [PMID: 29182047 DOI: 10.2217/pgs-2017-0044] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 4.0] [Reference Citation Analysis]
201 Chen Z, Wang J, Yang W, Chen J, Meng Y, Geng B, Cui Q, Yang J. FAM3A mediates PPARγ's protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress. Oncotarget 2017;8:49882-96. [PMID: 28562339 DOI: 10.18632/oncotarget.17805] [Cited by in Crossref: 16] [Cited by in F6Publishing: 17] [Article Influence: 4.0] [Reference Citation Analysis]
202 Kalra K, Eberhard J, Farbehi N, Chong JJ, Xaymardan M. Role of PDGF-A/B Ligands in Cardiac Repair After Myocardial Infarction. Front Cell Dev Biol 2021;9:669188. [PMID: 34513823 DOI: 10.3389/fcell.2021.669188] [Reference Citation Analysis]
203 Rosenwald IB. The role of translation in neoplastic transformation from a pathologist's point of view. Oncogene. 2004;23:3230-3247. [PMID: 15094773 DOI: 10.1038/sj.onc.1207552] [Cited by in Crossref: 81] [Cited by in F6Publishing: 76] [Article Influence: 4.5] [Reference Citation Analysis]
204 Yoganathan N, Yee A, Zhang Z, Leung D, Yan J, Fazli L, Kojic DL, Costello PC, Jabali M, Dedhar S, Sanghera J. Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties. Pharmacol Ther 2002;93:233-42. [PMID: 12191615 DOI: 10.1016/s0163-7258(02)00192-4] [Cited by in Crossref: 43] [Cited by in F6Publishing: 13] [Article Influence: 2.3] [Reference Citation Analysis]
205 Dumas E, Neagoe PE, McDonald PP, White M, Sirois MG. New Insights into the Pro-Inflammatory Activities of Ang1 on Neutrophils: Induction of MIP-1β Synthesis and Release. PLoS One 2016;11:e0163140. [PMID: 27632174 DOI: 10.1371/journal.pone.0163140] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.7] [Reference Citation Analysis]
206 Roy P, Nigam N, Singh M, George J, Srivastava S, Naqvi H, Shukla Y. Tea polyphenols inhibit cyclooxygenase-2 expression and block activation of nuclear factor-kappa B and Akt in diethylnitrosoamine induced lung tumors in Swiss mice. Invest New Drugs 2010;28:466-71. [PMID: 19517063 DOI: 10.1007/s10637-009-9274-0] [Cited by in Crossref: 17] [Cited by in F6Publishing: 14] [Article Influence: 1.3] [Reference Citation Analysis]
207 Ali AY, Farrand L, Kim JY, Byun S, Suh JY, Lee HJ, Tsang BK. Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrum. Ann N Y Acad Sci. 2012;1271:58-67. [PMID: 23050965 DOI: 10.1111/j.1749-6632.2012.06734.x] [Cited by in Crossref: 58] [Cited by in F6Publishing: 58] [Article Influence: 6.4] [Reference Citation Analysis]
208 Hammerich KH, Frolov A, Li R, Ittmann M, Ayala GE. Cellular interactions of the phosphorylated form of AKT in prostate cancer. Human Pathology 2017;63:98-109. [DOI: 10.1016/j.humpath.2017.02.014] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
209 Li Y, Kong D, Ahmad A, Bao B, Sarkar FH. Antioxidant function of isoflavone and 3,3'-diindolylmethane: are they important for cancer prevention and therapy? Antioxid Redox Signal 2013;19:139-50. [PMID: 23391445 DOI: 10.1089/ars.2013.5233] [Cited by in Crossref: 32] [Cited by in F6Publishing: 28] [Article Influence: 3.6] [Reference Citation Analysis]
210 Sarkar FH, Li Y. Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy. Acta Pharmacologica Sinica 2007;28:1305-15. [DOI: 10.1111/j.1745-7254.2007.00689.x] [Cited by in Crossref: 44] [Cited by in F6Publishing: 37] [Article Influence: 2.9] [Reference Citation Analysis]
211 Sakoda H, Gotoh Y, Katagiri H, Kurokawa M, Ono H, Onishi Y, Anai M, Ogihara T, Fujishiro M, Fukushima Y, Abe M, Shojima N, Kikuchi M, Oka Y, Hirai H, Asano T. Differing Roles of Akt and Serum- and Glucocorticoid-regulated Kinase in Glucose Metabolism, DNA Synthesis, and Oncogenic Activity. Journal of Biological Chemistry 2003;278:25802-7. [DOI: 10.1074/jbc.m301127200] [Cited by in Crossref: 89] [Cited by in F6Publishing: 34] [Article Influence: 4.7] [Reference Citation Analysis]
212 Neznanov N, Neznanova L, Kondratov RV, Burdelya L, Kandel ES, O'Rourke DM, Ullrich A, Gudkov AV. Dominant negative form of signal-regulatory protein-alpha (SIRPalpha /SHPS-1) inhibits tumor necrosis factor-mediated apoptosis by activation of NF-kappa B. J Biol Chem 2003;278:3809-15. [PMID: 12446684 DOI: 10.1074/jbc.M210698200] [Cited by in Crossref: 27] [Cited by in F6Publishing: 16] [Article Influence: 1.4] [Reference Citation Analysis]
213 Zhu QS, Ren W, Korchin B, Lahat G, Dicker A, Lu Y, Mills G, Pollock RE, Lev D. Soft tissue sarcoma cells are highly sensitive to AKT blockade: a role for p53-independent up-regulation of GADD45 alpha. Cancer Res 2008;68:2895-903. [PMID: 18413758 DOI: 10.1158/0008-5472.CAN-07-6268] [Cited by in Crossref: 40] [Cited by in F6Publishing: 24] [Article Influence: 2.9] [Reference Citation Analysis]
214 Zhang H, Wang Y, Xie JF, Liang X, Liu D, Yang P, Hsu H, Ray RB, Mountz JD. Regulation of tumor necrosis factor ?-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt. Arthritis & Rheumatism 2001;44:1555-67. [DOI: 10.1002/1529-0131(200107)44:7<1555::aid-art279>3.0.co;2-m] [Cited by in Crossref: 83] [Cited by in F6Publishing: 38] [Article Influence: 4.0] [Reference Citation Analysis]
215 Tessier C, Prigent-Tessier A, Ferguson-Gottschall S, Gu Y, Gibori G. PRL antiapoptotic effect in the rat decidua involves the PI3K/protein kinase B-mediated inhibition of caspase-3 activity. Endocrinology 2001;142:4086-94. [PMID: 11517188 DOI: 10.1210/endo.142.9.8381] [Cited by in Crossref: 23] [Cited by in F6Publishing: 31] [Article Influence: 1.1] [Reference Citation Analysis]
216 Neznanov N, Neznanova L, Kondratov RV, O'Rourke DM, Ullrich A, Gudkov AV. The ability of protein tyrosine phosphatase SHP-1 to suppress NFkappaB can be inhibited by dominant negative mutant of SIRPalpha. DNA Cell Biol 2004;23:175-82. [PMID: 15068587 DOI: 10.1089/104454904322964779] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 0.8] [Reference Citation Analysis]
217 Sajid M, Yan C, Li D, Merugu SB, Negi H, Khan MR. Potent anti-cancer activity of Alnus nitida against lung cancer cells; in vitro and in vivo studies. Biomed Pharmacother 2019;110:254-64. [PMID: 30508737 DOI: 10.1016/j.biopha.2018.11.138] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 1.3] [Reference Citation Analysis]
218 He Z, Cho Y, Ma W, Choi HS, Bode AM, Dong Z. Regulation of Ultraviolet B-induced Phosphorylation of Histone H3 at Serine 10 by Fyn Kinase. Journal of Biological Chemistry 2005;280:2446-54. [DOI: 10.1074/jbc.m402053200] [Cited by in Crossref: 36] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
219 Demoulin J, Essaghir A. PDGF receptor signaling networks in normal and cancer cells. Cytokine & Growth Factor Reviews 2014;25:273-83. [DOI: 10.1016/j.cytogfr.2014.03.003] [Cited by in Crossref: 143] [Cited by in F6Publishing: 132] [Article Influence: 17.9] [Reference Citation Analysis]
220 Zheng H, Dai T, Zhou B, Zhu J, Huang H, Wang M, Fu G. SDF-1α/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway. Atherosclerosis 2008;201:36-42. [DOI: 10.1016/j.atherosclerosis.2008.02.011] [Cited by in Crossref: 69] [Cited by in F6Publishing: 62] [Article Influence: 4.9] [Reference Citation Analysis]
221 Watters KM, Dean J, Hasegawa H, Sawa H, Hall W, Sheehy N. Cytokine and growth factor expression by HTLV-1 Lck-tax transgenic cells in SCID mice. AIDS Res Hum Retroviruses 2010;26:593-603. [PMID: 20438380 DOI: 10.1089/aid.2009.0212] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
222 Teng FY, Tang BL. NF-kappaB signaling in neurite growth and neuronal survival. Rev Neurosci 2010;21:299-313. [PMID: 21086762 DOI: 10.1515/revneuro.2010.21.4.299] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 1.3] [Reference Citation Analysis]
223 Lee NY, Chung K, Jin JS, Lee Y, An H. The Inhibitory Effect of Nodakenin on Mast‐Cell‐Mediated Allergic Inflammation Via Downregulation of NF‐κB and Caspase‐1 Activation. J Cell Biochem 2017;118:3993-4001. [DOI: 10.1002/jcb.26055] [Cited by in Crossref: 13] [Cited by in F6Publishing: 14] [Article Influence: 2.6] [Reference Citation Analysis]
224 Burow ME, Weldon CB, Melnik LI, Duong BN, Collins-Burow BM, Beckman BS, McLachlan JA. PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis. Biochem Biophys Res Commun 2000;271:342-5. [PMID: 10799299 DOI: 10.1006/bbrc.2000.2626] [Cited by in Crossref: 83] [Cited by in F6Publishing: 78] [Article Influence: 3.8] [Reference Citation Analysis]
225 Lopez-Bergami P, Barbero G. The emerging role of Wnt5a in the promotion of a pro-inflammatory and immunosuppressive tumor microenvironment. Cancer Metastasis Rev 2020;39:933-52. [PMID: 32435939 DOI: 10.1007/s10555-020-09878-7] [Cited by in Crossref: 10] [Cited by in F6Publishing: 15] [Article Influence: 10.0] [Reference Citation Analysis]
226 Lu Y, Tao F, Zhou MT, Tang KF. The signaling pathways that mediate the anti-cancer effects of caloric restriction. Pharmacol Res 2019;141:512-20. [PMID: 30641278 DOI: 10.1016/j.phrs.2019.01.021] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
227 Kane LP, Mollenauer MN, Xu Z, Turck CW, Weiss A. Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription. Mol Cell Biol. 2002;22:5962-5974. [PMID: 12138205 DOI: 10.1128/MCB.22.16.5962-5974.2002] [Cited by in Crossref: 116] [Cited by in F6Publishing: 44] [Article Influence: 5.8] [Reference Citation Analysis]
228 Shioda N, Han F, Moriguchi S, Fukunaga K. Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia: Calcineurin mediates Fas-ligand expression. Journal of Neurochemistry 2007;102:1506-17. [DOI: 10.1111/j.1471-4159.2007.04600.x] [Cited by in Crossref: 58] [Cited by in F6Publishing: 55] [Article Influence: 3.9] [Reference Citation Analysis]
229 Gerling N, Culmsee C, Klumpp S, Krieglstein J. The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons. Neurochemistry International 2004;44:505-20. [DOI: 10.1016/j.neuint.2003.08.013] [Cited by in Crossref: 18] [Cited by in F6Publishing: 19] [Article Influence: 1.0] [Reference Citation Analysis]
230 Steelman LS, Abrams SL, Whelan J, Bertrand FE, Ludwig DE, Bäsecke J, Libra M, Stivala F, Milella M, Tafuri A, Lunghi P, Bonati A, Martelli AM, Mccubrey JA. Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. Leukemia 2008;22:686-707. [DOI: 10.1038/leu.2008.26] [Cited by in Crossref: 251] [Cited by in F6Publishing: 246] [Article Influence: 17.9] [Reference Citation Analysis]
231 Yang S, Lin H, Diehl AM. Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation. Am J Physiol Gastrointest Liver Physiol 2001;281:G382-92. [PMID: 11447019 DOI: 10.1152/ajpgi.2001.281.2.G382] [Cited by in Crossref: 61] [Cited by in F6Publishing: 26] [Article Influence: 2.9] [Reference Citation Analysis]
232 Wong ML, Kaye AH, Hovens CM. Targeting malignant glioma survival signalling to improve clinical outcomes. Journal of Clinical Neuroscience 2007;14:301-8. [DOI: 10.1016/j.jocn.2006.11.005] [Cited by in Crossref: 70] [Cited by in F6Publishing: 66] [Article Influence: 4.7] [Reference Citation Analysis]
233 Yasuoka C, Ihara Y, Ikeda S, Miyahara Y, Kondo T, Kohno S. Antiapoptotic Activity of Akt Is Down-regulated by Ca2+ in Myocardiac H9c2 Cells. Journal of Biological Chemistry 2004;279:51182-92. [DOI: 10.1074/jbc.m407225200] [Cited by in Crossref: 37] [Cited by in F6Publishing: 6] [Article Influence: 2.1] [Reference Citation Analysis]
234 Schmitz I, Kirchhoff S, Krammer PH. Regulation of death receptor-mediated apoptosis pathways. Int J Biochem Cell Biol. 2000;32:1123-1136. [PMID: 11137452 DOI: 10.1016/s1357-2725(00)00048-0] [Cited by in Crossref: 167] [Cited by in F6Publishing: 55] [Article Influence: 8.0] [Reference Citation Analysis]
235 Fulda S. Shifting the balance of mitochondrial apoptosis: therapeutic perspectives. Front Oncol 2012;2:121. [PMID: 23061040 DOI: 10.3389/fonc.2012.00121] [Cited by in Crossref: 16] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
236 Zhu M, Li D, Wu Y, Huang X, Wu M. TREM-2 promotes macrophage-mediated eradication of Pseudomonas aeruginosa via a PI3K/Akt pathway. Scand J Immunol 2014;79:187-96. [PMID: 24383713 DOI: 10.1111/sji.12148] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 3.3] [Reference Citation Analysis]
237 Curnock AP, Logan MK, Ward SG. Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases. Immunology 2002;105:125-36. [PMID: 11872087 DOI: 10.1046/j.1365-2567.2002.01345.x] [Cited by in Crossref: 104] [Cited by in F6Publishing: 95] [Article Influence: 5.2] [Reference Citation Analysis]
238 Baldwin AS. NF-κB in Oncogenesis and As a Target for Cancer Therapy. In: Beyaert R, editor. Nuclear Factor кB. Dordrecht: Springer Netherlands; 2003. pp. 393-408. [DOI: 10.1007/978-94-010-0163-2_18] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
239 Sutherland CL, Chalupny NJ, Schooley K, VandenBos T, Kubin M, Cosman D. UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells. J Immunol 2002;168:671-9. [PMID: 11777960 DOI: 10.4049/jimmunol.168.2.671] [Cited by in Crossref: 182] [Cited by in F6Publishing: 170] [Article Influence: 9.1] [Reference Citation Analysis]
240 Tor YS, Yazan LS, Foo JB, Armania N, Cheah YK, Abdullah R, Imam MU, Ismail N, Ismail M. Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa. BMC Complement Altern Med 2014;14:55. [PMID: 24524627 DOI: 10.1186/1472-6882-14-55] [Cited by in Crossref: 35] [Cited by in F6Publishing: 29] [Article Influence: 4.4] [Reference Citation Analysis]
241 Zhuang S, Kochevar IE. Singlet oxygen-induced activation of Akt/protein kinase B is independent of growth factor receptors. Photochem Photobiol 2003;78:361-71. [PMID: 14626664 DOI: 10.1562/0031-8655(2003)078<0361:soaopk>2.0.co;2] [Cited by in Crossref: 30] [Cited by in F6Publishing: 15] [Article Influence: 1.7] [Reference Citation Analysis]
242 Shields JM, Pruitt K, McFall A, Shaub A, Der CJ. Understanding Ras: 'it ain't over 'til it's over'. Trends Cell Biol. 2000;10:147-154. [PMID: 10740269 DOI: 10.1016/S0962-8924(00)01740-2] [Cited by in Crossref: 553] [Cited by in F6Publishing: 206] [Article Influence: 25.1] [Reference Citation Analysis]
243 Liptay S, Weber CK, Ludwig L, Wagner M, Adler G, Schmid RM. Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer. Int J Cancer. 2003;105:735-746. [PMID: 12767057 DOI: 10.1002/ijc.11081] [Cited by in Crossref: 129] [Cited by in F6Publishing: 111] [Article Influence: 6.8] [Reference Citation Analysis]
244 Law NC, Hunzicker-Dunn ME. Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation. J Biol Chem 2016;291:4547-60. [PMID: 26702053 DOI: 10.1074/jbc.M115.698761] [Cited by in Crossref: 27] [Cited by in F6Publishing: 19] [Article Influence: 3.9] [Reference Citation Analysis]
245 Nishida S, Yoshioka S, Kinoshita-Kimoto S, Kotani M, Tsubaki M, Fujii Y, Tomura TT, Irimajiri K. Pretreatment with PKC inhibitor triggers TNF-alpha induced apoptosis in TNF-alpha-resistant B16 melanoma BL6 cells. Life Sci 2003;74:781-92. [PMID: 14654170 DOI: 10.1016/j.lfs.2003.07.012] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.3] [Reference Citation Analysis]
246 Smith D, Shimamura T, Barbera S, Bejcek BE. NF-kappaB controls growth of glioblastomas/astrocytomas. Mol Cell Biochem 2008;307:141-7. [PMID: 17828582 DOI: 10.1007/s11010-007-9593-4] [Cited by in Crossref: 38] [Cited by in F6Publishing: 37] [Article Influence: 2.5] [Reference Citation Analysis]
247 Liu Y, Wang Y, Yamakuchi M, Masuda S, Tokioka T, Yamaoka S, Maruyama I, Kitajima I. Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax. Oncogene 2001;20:2514-26. [DOI: 10.1038/sj.onc.1204364] [Cited by in Crossref: 48] [Cited by in F6Publishing: 54] [Article Influence: 2.3] [Reference Citation Analysis]
248 Brunet A, Datta SR, Greenberg ME. Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol. 2001;11:297-305. [PMID: 11399427 DOI: 10.1016/s0959-4388(00)00211-7] [Cited by in Crossref: 831] [Cited by in F6Publishing: 352] [Article Influence: 39.6] [Reference Citation Analysis]
249 Lassus P, Roux P, Zugasti O, Philips A, Fort P, Hibner U. Extinction of Rac1 and Cdc42Hs signalling defines a novel p53-dependent apoptotic pathway. Oncogene 2000;19:2377-85. [DOI: 10.1038/sj.onc.1203553] [Cited by in Crossref: 30] [Cited by in F6Publishing: 29] [Article Influence: 1.4] [Reference Citation Analysis]
250 Suri S, Mirza MA, Anwer MK, Alshetaili AS, Alshahrani SM, Ahmed FJ, Iqbal Z. Development of NIPAAm-PEG acrylate polymeric nanoparticles for co-delivery of paclitaxel with ellagic acid for the treatment of breast cancer. Journal of Polymer Engineering 2019;39:271-8. [DOI: 10.1515/polyeng-2018-0169] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 1.3] [Reference Citation Analysis]
251 Flusberg DA, Numaguchi Y, Ingber DE. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Mol Biol Cell 2001;12:3087-94. [PMID: 11598193 DOI: 10.1091/mbc.12.10.3087] [Cited by in Crossref: 67] [Cited by in F6Publishing: 61] [Article Influence: 3.4] [Reference Citation Analysis]
252 Zhang N, Yin Y, Xu SJ, Chen WS. 5-Fluorouracil: mechanisms of resistance and reversal strategies. Molecules. 2008;13:1551-1569. [PMID: 18794772 DOI: 10.3390/molecules13081551] [Cited by in Crossref: 291] [Cited by in F6Publishing: 269] [Article Influence: 20.8] [Reference Citation Analysis]
253 Chopra M, Schrenk D. Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death. Crit Rev Toxicol 2011;41:292-320. [PMID: 21323611 DOI: 10.3109/10408444.2010.524635] [Cited by in Crossref: 64] [Cited by in F6Publishing: 56] [Article Influence: 5.8] [Reference Citation Analysis]
254 Deng XT, Tang SM, Wu PY, Li QP, Ge XX, Xu BM, Wang HS, Miao L. SP/NK-1R promotes gallbladder cancer cell proliferation and migration. J Cell Mol Med 2019;23:7961-73. [PMID: 30903649 DOI: 10.1111/jcmm.14230] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
255 Krishnan K, Steptoe AL, Martin HC, Pattabiraman DR, Nones K, Waddell N, Mariasegaram M, Simpson PT, Lakhani SR, Vlassov A, Grimmond SM, Cloonan N. miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA 2013;19:1767-80. [PMID: 24158791 DOI: 10.1261/rna.042143.113] [Cited by in Crossref: 99] [Cited by in F6Publishing: 94] [Article Influence: 11.0] [Reference Citation Analysis]
256 Carlin CR. New Insights to Adenovirus-Directed Innate Immunity in Respiratory Epithelial Cells. Microorganisms 2019;7:E216. [PMID: 31349602 DOI: 10.3390/microorganisms7080216] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.7] [Reference Citation Analysis]
257 Cai Y, Wang J, Li R, Ayala G, Ittmann M, Liu M. GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression. Cancer Res 2009;69:819-27. [PMID: 19176382 DOI: 10.1158/0008-5472.CAN-08-2537] [Cited by in Crossref: 27] [Cited by in F6Publishing: 25] [Article Influence: 2.1] [Reference Citation Analysis]
258 Bozinovski S, Jones JE, Vlahos R, Hamilton JA, Anderson GP. Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo. J Biol Chem. 2002;277:42808-42814. [PMID: 12208854 DOI: 10.1074/jbc.m207840200] [Cited by in Crossref: 118] [Cited by in F6Publishing: 54] [Article Influence: 5.9] [Reference Citation Analysis]
259 Madrid LV, Wang CY, Guttridge DC, Schottelius AJ, Baldwin AS Jr, Mayo MW. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Mol Cell Biol 2000;20:1626-38. [PMID: 10669740 DOI: 10.1128/MCB.20.5.1626-1638.2000] [Cited by in Crossref: 487] [Cited by in F6Publishing: 142] [Article Influence: 22.1] [Reference Citation Analysis]
260 Volling K, Thywissen A, Brakhage AA, Saluz HP. Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling. Cell Microbiol 2011;13:1130-48. [PMID: 21501368 DOI: 10.1111/j.1462-5822.2011.01605.x] [Cited by in Crossref: 52] [Cited by in F6Publishing: 51] [Article Influence: 4.7] [Reference Citation Analysis]
261 Windebank AJ, Mcdonald ES. Neurotrophic Factors in the Peripheral Nervous System. Peripheral Neuropathy. Elsevier; 2005. pp. 377-86. [DOI: 10.1016/b978-0-7216-9491-7.50020-x] [Cited by in Crossref: 10] [Article Influence: 0.6] [Reference Citation Analysis]
262 Wu H, Yang TY, Li Y, Ye WL, Liu F, He XS, Wang JR, Gan WJ, Li XM, Zhang S, Zhao YY, Li JM. Tumor Necrosis Factor Receptor-Associated Factor 6 Promotes Hepatocarcinogenesis by Interacting With Histone Deacetylase 3 to Enhance c-Myc Gene Expression and Protein Stability. Hepatology 2020;71:148-63. [PMID: 31155734 DOI: 10.1002/hep.30801] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 4.0] [Reference Citation Analysis]
263 Muraoka RS, Koh Y, Roebuck LR, Sanders ME, Brantley-Sieders D, Gorska AE, Moses HL, Arteaga CL. Increased malignancy of Neu-induced mammary tumors overexpressing active transforming growth factor beta1. Mol Cell Biol. 2003;23:8691-8703. [PMID: 14612410 DOI: 10.1128/MCB.23.23.8691-8703.2003] [Cited by in Crossref: 149] [Cited by in F6Publishing: 84] [Article Influence: 7.8] [Reference Citation Analysis]
264 Choy G, Liu JW, Chandra D, Tang DG. Cell survival signaling during apoptosis: implications in drug resistance and anti-cancer therapeutic development. Prog Drug Res 2005;63:115-45. [PMID: 16265879 DOI: 10.1007/3-7643-7414-4_6] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
265 Fonteh AN, Marion CR, Barham BJ, Edens MB, Atsumi G, Samet JM, High KP, Chilton FH. Enhancement of mast cell survival: a novel function of some secretory phospholipase A(2) isotypes. J Immunol. 2001;167:4161-4171. [PMID: 11591736 DOI: 10.4049/jimmunol.167.8.4161] [Cited by in Crossref: 22] [Cited by in F6Publishing: 23] [Article Influence: 1.0] [Reference Citation Analysis]
266 Mayo MW, Denlinger CE, Broad RM, Yeung F, Reilly ET, Shi Y, Jones DR. Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J Biol Chem 2003;278:18980-9. [PMID: 12649266 DOI: 10.1074/jbc.M211695200] [Cited by in Crossref: 142] [Cited by in F6Publishing: 56] [Article Influence: 7.5] [Reference Citation Analysis]
267 Jiang T, Grabiner B, Zhu Y, Jiang C, Li H, You Y, Lang J, Hung MC, Lin X. CARMA3 is crucial for EGFR-Induced activation of NF-κB and tumor progression. Cancer Res 2011;71:2183-92. [PMID: 21406399 DOI: 10.1158/0008-5472.CAN-10-3626] [Cited by in Crossref: 67] [Cited by in F6Publishing: 40] [Article Influence: 6.1] [Reference Citation Analysis]
268 Deng Y, Deng Y, He X, Chu J, Zhou J, Zhang Q, Guo W, Huang P, Guan X, Tang Y, Wei Y, Zhao S, Zhang X, Wei C, Namaka M, Yi P, Yu J, Li X. Prenatal inflammation-induced NF-κB dyshomeostasis contributes to renin-angiotensin system over-activity resulting in prenatally programmed hypertension in offspring. Sci Rep 2016;6:21692. [PMID: 26877256 DOI: 10.1038/srep21692] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 2.7] [Reference Citation Analysis]
269 Morley SP, Bierer BE. The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction. Elsevier; 2001. pp. 1-43. [DOI: 10.1016/s0065-2776(01)77013-7] [Cited by in Crossref: 4] [Article Influence: 0.2] [Reference Citation Analysis]
270 Natarajan U, Venkatesan T, Dhandayuthapani S, Dondapatti P, Rathinavelu A. Differential mechanisms involved in RG-7388 and Nutlin-3 induced cell death in SJSA-1 osteosarcoma cells. Cell Signal 2020;75:109742. [PMID: 32827690 DOI: 10.1016/j.cellsig.2020.109742] [Reference Citation Analysis]
271 Chadha R, Bhalla Y, Jain A, Chadha K, Karan M. Dietary Soy Isoflavone: A Mechanistic Insight. Natural Product Communications 2017;12:1934578X1701200. [DOI: 10.1177/1934578x1701200439] [Cited by in Crossref: 6] [Article Influence: 1.2] [Reference Citation Analysis]
272 Stout MC, Asiimwe E, Birkenstamm JR, Kim SY, Campbell PM. Analyzing Ras-associated cell proliferation signaling. Methods Mol Biol 2014;1170:393-409. [PMID: 24906326 DOI: 10.1007/978-1-4939-0888-2_21] [Cited by in Crossref: 10] [Cited by in F6Publishing: 6] [Article Influence: 1.4] [Reference Citation Analysis]
273 He YT, Liu DW, Ding LY, Li Q, Xiao YH. Therapeutic effects and molecular mechanisms of anti-fibrosis herbs and selenium on rats with hepatic fibrosis. World J Gastroenterol 2004; 10(5): 703-706 [PMID: 14991942 DOI: 10.3748/wjg.v10.i5.703] [Cited by in CrossRef: 13] [Cited by in F6Publishing: 13] [Article Influence: 0.7] [Reference Citation Analysis]
274 Jeay S, Sonenshein GE, Postel-Vinay MC, Kelly PA, Baixeras E. Growth hormone can act as a cytokine controlling survival and proliferation of immune cells: new insights into signaling pathways. Mol Cell Endocrinol. 2002;188:1-7. [PMID: 11911939 DOI: 10.1016/s0303-7207(02)00014-x] [Cited by in Crossref: 85] [Cited by in F6Publishing: 24] [Article Influence: 4.3] [Reference Citation Analysis]
275 Shimamura A, Ballif BA, Richards SA, Blenis J. Rsk1 mediates a MEK-MAP kinase cell survival signal. Curr Biol 2000;10:127-35. [PMID: 10679322 DOI: 10.1016/s0960-9822(00)00310-9] [Cited by in Crossref: 209] [Cited by in F6Publishing: 98] [Article Influence: 9.5] [Reference Citation Analysis]
276 Kovacs K, Hanto K, Bognar Z, Tapodi A, Bognar E, Kiss GN, Szabo A, Rappai G, Kiss T, Sumegi B, Gallyas F Jr. Prevalent role of Akt and ERK activation in cardioprotective effect of Ca(2+) channel- and beta-adrenergic receptor blockers. Mol Cell Biochem 2009;321:155-64. [PMID: 18975057 DOI: 10.1007/s11010-008-9929-8] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 1.4] [Reference Citation Analysis]
277 Yang K, Arcaroli JJ, Abraham E. Early Alterations in Neutrophil Activation Are Associated with Outcome in Acute Lung Injury. Am J Respir Crit Care Med 2003;167:1567-74. [DOI: 10.1164/rccm.200207-664oc] [Cited by in Crossref: 101] [Cited by in F6Publishing: 46] [Article Influence: 5.3] [Reference Citation Analysis]
278 Nemenoff RA, Weiser-Evans M, Winn RA. Activation and Molecular Targets of Peroxisome Proliferator-Activated Receptor-gamma Ligands in Lung Cancer. PPAR Res 2008;2008:156875. [PMID: 18509496 DOI: 10.1155/2008/156875] [Cited by in Crossref: 16] [Cited by in F6Publishing: 14] [Article Influence: 1.5] [Reference Citation Analysis]
279 Ge X, Zhao L, He L, Chen W, Li X. Vascular endothelial growth factor receptor 2 (VEGFR2, Flk-1/KDR) protects HEK293 cells against CoCl 2 -induced hypoxic toxicity: KDR PROTECTS HEK293 CELLS. Cell Biochem Funct 2012;30:151-7. [DOI: 10.1002/cbf.1829] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
280 Cho DH, Lee HJ, Kim HJ, Hong SH, Pyo JO, Cho C, Jung YK. Suppression of hypoxic cell death by APIP-induced sustained activation of AKT and ERK1/2. Oncogene 2007;26:2809-14. [PMID: 17086211 DOI: 10.1038/sj.onc.1210080] [Cited by in Crossref: 24] [Cited by in F6Publishing: 26] [Article Influence: 1.5] [Reference Citation Analysis]
281 Bhushan S, Malik F, Kumar A, Isher HK, Kaur IP, Taneja SC, Singh J. Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata. Mol Carcinog 2009;48:1093-108. [PMID: 19544329 DOI: 10.1002/mc.20559] [Cited by in Crossref: 29] [Cited by in F6Publishing: 23] [Article Influence: 2.2] [Reference Citation Analysis]
282 Aggarwal BB, Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol. 2006;71:1397-1421. [PMID: 16563357 DOI: 10.1016/j.bcp.2006.02.009] [Cited by in Crossref: 1115] [Cited by in F6Publishing: 959] [Article Influence: 69.7] [Reference Citation Analysis]
283 Paula FM, Barbosa HC, Carneiro EM, Persaud SJ, Gagliardino JJ, Boschero AC, Souza KL. Requirement of NF-kappaB signalling pathway for modulation of the cholinergic muscarinic M3 receptor expression by INGAP-PP in insulin-producing cells. European Journal of Pharmacology 2010;642:37-46. [DOI: 10.1016/j.ejphar.2010.05.056] [Cited by in Crossref: 11] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
284 Akca H, Akan SY, Yanikoglu A, Ozes ON. Suppression of TNF-α Mediated Apoptosis by EGF in TNF-α Sensitive Human Cervical Carcinoma Cell Line. Growth Factors 2009;21:31-9. [DOI: 10.1080/0897719031000115369] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
285 Ciechomska I, Pyrzynska B, Kazmierczak P, Kaminska B. Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells. Oncogene 2003;22:7617-27. [DOI: 10.1038/sj.onc.1207137] [Cited by in Crossref: 60] [Cited by in F6Publishing: 60] [Article Influence: 3.2] [Reference Citation Analysis]
286 Shao G, Gao C, Lu G. Alterations of Hypoxia-Inducible Factor-1 Alpha in the Hippocampus of Mice Acutely and Repeatedly Exposed to Hypoxia. Neurosignals 2005;14:255-61. [DOI: 10.1159/000088641] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 1.1] [Reference Citation Analysis]
287 Tas SW, Vervoordeldonk MJ, Tak PP. Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer. Curr Gene Ther 2009;9:160-70. [PMID: 19519361 DOI: 10.2174/156652309788488569] [Cited by in Crossref: 46] [Cited by in F6Publishing: 37] [Article Influence: 3.5] [Reference Citation Analysis]
288 Zhong X, Rescorla FJ. Cell surface adhesion molecules and adhesion-initiated signaling: understanding of anoikis resistance mechanisms and therapeutic opportunities. Cell Signal 2012;24:393-401. [PMID: 22024283 DOI: 10.1016/j.cellsig.2011.10.005] [Cited by in Crossref: 86] [Cited by in F6Publishing: 73] [Article Influence: 7.8] [Reference Citation Analysis]
289 Condorelli G, Morisco C, Latronico MV, Claudio PP, Dent P, Tsichlis P, Condorelli G, Frati G, Drusco A, Croce CM, Napoli C. TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor. FASEB J 2002;16:1732-7. [PMID: 12409315 DOI: 10.1096/fj.02-0419com] [Cited by in Crossref: 54] [Cited by in F6Publishing: 51] [Article Influence: 2.7] [Reference Citation Analysis]
290 Li QQ, Lee RX, Liang H, Wang G, Li JM, Zhong Y, Reed E. β-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK. Int J Oncol 2013;43:721-8. [PMID: 23817665 DOI: 10.3892/ijo.2013.1996] [Cited by in Crossref: 34] [Cited by in F6Publishing: 32] [Article Influence: 3.8] [Reference Citation Analysis]
291 Zhu L, Guan H, Cui C, Tian S, Yang D, Wang X, Zhang S, Wang L, Jiang H. Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo. Int J Mol Med 2012;30:1034-40. [PMID: 22922870 DOI: 10.3892/ijmm.2012.1100] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
292 Giardina C, Hubbard AK. Growing old with nuclear factor-kappaB. Cell Stress Chaperones 2002;7:207-12. [PMID: 12380689 DOI: 10.1379/1466-1268(2002)007<0207:gownfb>2.0.co;2] [Cited by in Crossref: 21] [Cited by in F6Publishing: 11] [Article Influence: 1.1] [Reference Citation Analysis]
293 Qin C, Nguyen T, Stewart J, Samudio I, Burghardt R, Safe S. Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex. Mol Endocrinol 2002;16:1793-809. [PMID: 12145335 DOI: 10.1210/me.2002-0006] [Cited by in Crossref: 39] [Cited by in F6Publishing: 35] [Article Influence: 2.1] [Reference Citation Analysis]
294 Manavathi B, Kumar R. Steering estrogen signals from the plasma membrane to the nucleus: Two sides of the coin. J Cell Physiol 2006;207:594-604. [DOI: 10.1002/jcp.20551] [Cited by in Crossref: 132] [Cited by in F6Publishing: 102] [Article Influence: 8.3] [Reference Citation Analysis]
295 Sun Y, Zhao Y, Wang X, Zhao L, Li W, Ding Y, Kong L, Guo Q, Lu N. Wogonoside prevents colitis-associated colorectal carcinogenesis and colon cancer progression in inflammation-related microenvironment via inhibiting NF-κB activation through PI3K/Akt pathway. Oncotarget 2016;7:34300-15. [PMID: 27102438 DOI: 10.18632/oncotarget.8815] [Cited by in Crossref: 23] [Cited by in F6Publishing: 27] [Article Influence: 5.8] [Reference Citation Analysis]
296 Maurer U, Charvet C, Wagman AS, Dejardin E, Green DR. Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1. Molecular Cell 2006;21:749-60. [DOI: 10.1016/j.molcel.2006.02.009] [Cited by in Crossref: 614] [Cited by in F6Publishing: 595] [Article Influence: 38.4] [Reference Citation Analysis]
297 Reddy SA, Huang JH, Liao WS. Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation. J Immunol. 2000;164:1355-1363. [PMID: 10640750 DOI: 10.4049/jimmunol.164.3.1355] [Cited by in Crossref: 138] [Cited by in F6Publishing: 141] [Article Influence: 6.3] [Reference Citation Analysis]
298 Sugatani T, Hruska KA. Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors. J Biol Chem 2005;280:3583-9. [PMID: 15545269 DOI: 10.1074/jbc.M410480200] [Cited by in Crossref: 143] [Cited by in F6Publishing: 66] [Article Influence: 7.9] [Reference Citation Analysis]
299 Ghosh-Choudhury N, Mandal CC, Choudhury GG. Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation. J Biol Chem 2007;282:4983-93. [PMID: 17179158 DOI: 10.1074/jbc.M606706200] [Cited by in Crossref: 104] [Cited by in F6Publishing: 42] [Article Influence: 6.5] [Reference Citation Analysis]
300 Lauder A, Castellanos A, Weston K. c-Myb transcription is activated by protein kinase B (PKB) following interleukin 2 stimulation of Tcells and is required for PKB-mediated protection from apoptosis. Mol Cell Biol 2001;21:5797-805. [PMID: 11486019 DOI: 10.1128/MCB.21.17.5797-5805.2001] [Cited by in Crossref: 62] [Cited by in F6Publishing: 18] [Article Influence: 3.0] [Reference Citation Analysis]
301 Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, Schmidt M, Mills GB, Mendelsohn J, Fan Z. HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Oncogene. 2003;22:3205-3212. [PMID: 12761490 DOI: 10.1038/sj.onc.1206394] [Cited by in Crossref: 317] [Cited by in F6Publishing: 289] [Article Influence: 16.7] [Reference Citation Analysis]
302 Antonia RJ, Hagan RS, Baldwin AS. Expanding the View of IKK: New Substrates and New Biology. Trends Cell Biol 2021;31:166-78. [PMID: 33422358 DOI: 10.1016/j.tcb.2020.12.003] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
303 Park CS, Schneider IC, Haugh JM. Kinetic analysis of platelet-derived growth factor receptor/phosphoinositide 3-kinase/Akt signaling in fibroblasts. J Biol Chem 2003;278:37064-72. [PMID: 12871957 DOI: 10.1074/jbc.M304968200] [Cited by in Crossref: 79] [Cited by in F6Publishing: 45] [Article Influence: 4.2] [Reference Citation Analysis]
304 Stafeev IS, Vorotnikov AV, Ratner EI, Menshikov MY, Parfyonova YV. Latent Inflammation and Insulin Resistance in Adipose Tissue. Int J Endocrinol 2017;2017:5076732. [PMID: 28912810 DOI: 10.1155/2017/5076732] [Cited by in Crossref: 34] [Cited by in F6Publishing: 32] [Article Influence: 6.8] [Reference Citation Analysis]
305 Zhao N, Coyne J, Abune L, Shi P, Lian XL, Zhang G, Wang Y. Exogenous Signaling Molecules Released from Aptamer-Functionalized Hydrogels Promote the Survival of Mesenchymal Stem Cell Spheroids. ACS Appl Mater Interfaces 2020;12:24599-610. [PMID: 32384232 DOI: 10.1021/acsami.0c05681] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
306 Chen M, Wu X, Tao G, Liu C, Chen J, Wang L, Lu P. Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro. Int J Cancer 2012;131:2487-98. [DOI: 10.1002/ijc.27548] [Cited by in Crossref: 36] [Cited by in F6Publishing: 38] [Article Influence: 3.6] [Reference Citation Analysis]
307 Jackson-bernitsas DG, Ichikawa H, Takada Y, Myers JN, Lin XL, Darnay BG, Chaturvedi MM, Aggarwal BB. Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-κB activation and proliferation in human head and neck squamous cell carcinoma. Oncogene 2007;26:1385-97. [DOI: 10.1038/sj.onc.1209945] [Cited by in Crossref: 134] [Cited by in F6Publishing: 127] [Article Influence: 8.4] [Reference Citation Analysis]
308 Baumgartner M, Chaussepied M, Moreau M, Werling D, Davis WC, Garcia A, Langsley G. Constitutive PI3-K activity is essential for proliferation, but not survival, of Theileria parva-transformed B cells. Cell Microbiol 2000;2:329-39. [DOI: 10.1046/j.1462-5822.2000.00062.x] [Cited by in Crossref: 53] [Cited by in F6Publishing: 48] [Article Influence: 2.4] [Reference Citation Analysis]
309 Matsuzaki H, Namikawa K, Kiyama H, Mori N, Sato K. Brain-derived neurotrophic factor rescues neuronal death induced by methamphetamine. Biol Psychiatry 2004;55:52-60. [PMID: 14706425 DOI: 10.1016/s0006-3223(03)00785-6] [Cited by in Crossref: 32] [Cited by in F6Publishing: 10] [Article Influence: 1.8] [Reference Citation Analysis]
310 Feng Y, Bhatt AJ, Fratkin JD, Rhodes PG. Neuroprotective effects of sodium orthovanadate after hypoxic-ischemic brain injury in neonatal rats. Brain Res Bull 2008;76:102-8. [PMID: 18395618 DOI: 10.1016/j.brainresbull.2008.01.012] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 0.5] [Reference Citation Analysis]
311 Biswas DK, Dai SC, Cruz A, Weiser B, Graner E, Pardee AB. The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers. Proc Natl Acad Sci U S A 2001;98:10386-91. [PMID: 11517301 DOI: 10.1073/pnas.151257998] [Cited by in Crossref: 116] [Cited by in F6Publishing: 99] [Article Influence: 5.5] [Reference Citation Analysis]
312 Agarwal E, Brattain MG, Chowdhury S. Cell survival and metastasis regulation by Akt signaling in colorectal cancer. Cell Signal. 2013;25:1711-1719. [PMID: 23603750 DOI: 10.1016/j.cellsig.2013.03.025] [Cited by in Crossref: 103] [Cited by in F6Publishing: 97] [Article Influence: 11.4] [Reference Citation Analysis]
313 Kashii Y, Uchida M, Kirito K, Tanaka M, Nishijima K, Toshima M, Ando T, Koizumi K, Endoh T, Sawada K, Momoi M, Miura Y, Ozawa K, Komatsu N. A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction. Blood 2000;96:941-9. [DOI: 10.1182/blood.v96.3.941] [Cited by in Crossref: 107] [Article Influence: 4.9] [Reference Citation Analysis]
314 Nori S, Nakamura M, Okano H. Plasticity and regeneration in the injured spinal cord after cell transplantation therapy. Functional Neural Transplantation IV - Translation to Clinical Application, Part B. Elsevier; 2017. pp. 33-56. [DOI: 10.1016/bs.pbr.2016.12.007] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 2.8] [Reference Citation Analysis]
315 Korn SH, Wouters EF, Vos N, Janssen-heininger YM. Cytokine-induced Activation of Nuclear Factor-κB Is Inhibited by Hydrogen Peroxide through Oxidative Inactivation of IκB Kinase. Journal of Biological Chemistry 2001;276:35693-700. [DOI: 10.1074/jbc.m104321200] [Cited by in Crossref: 145] [Cited by in F6Publishing: 55] [Article Influence: 6.9] [Reference Citation Analysis]
316 Johnson LR. Apoptosis in the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract. Elsevier; 2006. pp. 345-73. [DOI: 10.1016/b978-012088394-3/50015-5] [Cited by in Crossref: 2] [Article Influence: 0.1] [Reference Citation Analysis]
317 Vantler M, Caglayan E, Zimmermann WH, Bäumer AT, Rosenkranz S. Systematic Evaluation of Anti-apoptotic Growth Factor Signaling in Vascular Smooth Muscle Cells. Journal of Biological Chemistry 2005;280:14168-76. [DOI: 10.1074/jbc.m413310200] [Cited by in Crossref: 41] [Cited by in F6Publishing: 15] [Article Influence: 2.4] [Reference Citation Analysis]
318 Wang VY, Li Y, Kim D, Zhong X, Du Q, Ghassemian M, Ghosh G. Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity. Mol Cell 2017;67:484-497.e5. [PMID: 28689659 DOI: 10.1016/j.molcel.2017.06.011] [Cited by in Crossref: 26] [Cited by in F6Publishing: 24] [Article Influence: 5.2] [Reference Citation Analysis]
319 Thrash BR, Menges CW, Pierce RH, McCance DJ. AKT1 provides an essential survival signal required for differentiation and stratification of primary human keratinocytes. J Biol Chem 2006;281:12155-62. [PMID: 16517604 DOI: 10.1074/jbc.M512116200] [Cited by in Crossref: 59] [Cited by in F6Publishing: 26] [Article Influence: 3.7] [Reference Citation Analysis]
320 So T, Croft M. Regulation of the PKCθ-NF-κB Axis in T Lymphocytes by the Tumor Necrosis Factor Receptor Family Member OX40. Front Immunol 2012;3:133. [PMID: 22654884 DOI: 10.3389/fimmu.2012.00133] [Cited by in Crossref: 9] [Cited by in F6Publishing: 11] [Article Influence: 0.9] [Reference Citation Analysis]
321 Bonavia R, Inda MM, Vandenberg S, Cheng SY, Nagane M, Hadwiger P, Tan P, Sah DW, Cavenee WK, Furnari FB. EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway. Oncogene 2012;31:4054-66. [PMID: 22139077 DOI: 10.1038/onc.2011.563] [Cited by in Crossref: 108] [Cited by in F6Publishing: 105] [Article Influence: 9.8] [Reference Citation Analysis]
322 Mu W, Wang Z, Ma C, Jiang Y, Zhang N, Hu K, Li L, Wang Z. Metformin promotes the proliferation and differentiation of murine preosteoblast by regulating the expression of sirt6 and oct4. Pharmacol Res. 2018;129:462-474. [PMID: 29162538 DOI: 10.1016/j.phrs.2017.11.020] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 3.8] [Reference Citation Analysis]
323 Kohno T, Kubo Y, Yasui K, Haraguchi M, Shigematsu S, Chua KJ, Matsuyama T, Hayashi H. Serum starvation activates NF-κB through G protein β2 subunit-mediated signal. DNA Cell Biol 2012;31:1636-44. [PMID: 22917497 DOI: 10.1089/dna.2012.1666] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.7] [Reference Citation Analysis]
324 Mehrhof FB, Müller FU, Bergmann MW, Li P, Wang Y, Schmitz W, Dietz R, von Harsdorf R. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein. Circulation. 2001;104:2088-2094. [PMID: 11673351 DOI: 10.1161/hc4201.097133] [Cited by in Crossref: 117] [Cited by in F6Publishing: 116] [Article Influence: 5.6] [Reference Citation Analysis]
325 Basse AL, Dixen K, Yadav R, Tygesen MP, Qvortrup K, Kristiansen K, Quistorff B, Gupta R, Wang J, Hansen JB. Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling. BMC Genomics 2015;16:215. [PMID: 25887780 DOI: 10.1186/s12864-015-1405-8] [Cited by in Crossref: 32] [Cited by in F6Publishing: 29] [Article Influence: 4.6] [Reference Citation Analysis]
326 Koduru S, Sowmyalakshmi S, Kumar R, Gomathinayagam R, Rohr J, Damodaran C. Identification of a potent herbal molecule for the treatment of breast cancer. BMC Cancer 2009;9:41. [PMID: 19183448 DOI: 10.1186/1471-2407-9-41] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
327 Fan Q, Yin X, Rababa'h A, Diaz Diaz A, Wijaya CS, Singh S, Suryavanshi SV, Vo HH, Saeed M, Zhang Y, McConnell BK. Absence of gravin-mediated signaling inhibits development of high-fat diet-induced hyperlipidemia and atherosclerosis. Am J Physiol Heart Circ Physiol 2019;317:H793-810. [PMID: 31441691 DOI: 10.1152/ajpheart.00215.2019] [Reference Citation Analysis]
328 Higa M, Shimabukuro M, Shimajiri Y, Takasu N, Shinjyo T, Inaba T. Protein kinase B/Akt signalling is required for palmitate-induced beta-cell lipotoxicity. Diabetes Obes Metab 2006;8:228-33. [PMID: 16448528 DOI: 10.1111/j.1463-1326.2005.00488.x] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 1.4] [Reference Citation Analysis]
329 Wiese S, Beck M, Karch C, Sendtner M. Signalling mechanisms for survival of lesioned motoneurons. Acta Neurochir Suppl 2004;89:21-35. [PMID: 15335098 DOI: 10.1007/978-3-7091-0603-7_4] [Cited by in Crossref: 3] [Cited by in F6Publishing: 6] [Article Influence: 0.2] [Reference Citation Analysis]
330 Haga M, Yamashita A, Paszkowiak J, Sumpio BE, Dardik A. Oscillatory shear stress increases smooth muscle cell proliferation and Akt phosphorylation. J Vasc Surg 2003;37:1277-84. [PMID: 12764276 DOI: 10.1016/s0741-5214(03)00329-x] [Cited by in Crossref: 53] [Cited by in F6Publishing: 17] [Article Influence: 2.8] [Reference Citation Analysis]
331 Zhu Y, Liu B, Zheng X, Wu J, Chen S, Chen Z, Chen T, Huang Z, Lei W. Partial decortication ameliorates dopamine depletion‑induced striatal neuron lesions in rats. Int J Mol Med 2019;44:1414-24. [PMID: 31364729 DOI: 10.3892/ijmm.2019.4288] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
332 Kasaj A, Willershausen B, Reichert C, Gortan-kasaj A, Zafiropoulos G, Schmidt M. Human periodontal fibroblast response to a nanostructured hydroxyapatite bone replacement graft in vitro. Archives of Oral Biology 2008;53:683-9. [DOI: 10.1016/j.archoralbio.2008.01.009] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 1.4] [Reference Citation Analysis]
333 Kawano A, Kadomatsu R, Ono M, Kojima S, Tsukimoto M, Sakamoto H. Autocrine Regulation of UVA-Induced IL-6 Production via Release of ATP and Activation of P2Y Receptors. PLoS One 2015;10:e0127919. [PMID: 26030257 DOI: 10.1371/journal.pone.0127919] [Cited by in Crossref: 15] [Cited by in F6Publishing: 12] [Article Influence: 2.1] [Reference Citation Analysis]
334 Carneiro BA, Kaplan JB, Altman JK, Giles FJ, Platanias LC. Targeting mTOR signaling pathways and related negative feedback loops for the treatment of acute myeloid leukemia. Cancer Biol Ther 2015;16:648-56. [PMID: 25801978 DOI: 10.1080/15384047.2015.1026510] [Cited by in Crossref: 23] [Cited by in F6Publishing: 23] [Article Influence: 3.8] [Reference Citation Analysis]
335 Meng F, Liu L, Chin PC, D'Mello SR. Akt is a downstream target of NF-kappa B. J Biol Chem. 2002;277:29674-29680. [PMID: 12052823 DOI: 10.1074/jbc.M112464200] [Cited by in Crossref: 135] [Cited by in F6Publishing: 62] [Article Influence: 6.8] [Reference Citation Analysis]
336 Parhar K, Eivemark S, Assi K, Gómez-Muñoz A, Yee A, Salh B. Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events. Mol Cell Biochem 2007;300:113-27. [PMID: 17136479 DOI: 10.1007/s11010-006-9375-4] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.2] [Reference Citation Analysis]
337 Hiscott J, Kwon H, Génin P. Hostile takeovers: viral appropriation of the NF-kappaB pathway. J Clin Invest. 2001;107:143-151. [PMID: 11160127 DOI: 10.1172/JCI11918] [Cited by in Crossref: 401] [Cited by in F6Publishing: 214] [Article Influence: 19.1] [Reference Citation Analysis]
338 Iavarone C, Catania A, Marinissen MJ, Visconti R, Acunzo M, Tarantino C, Carlomagno MS, Bruni CB, Gutkind JS, Chiariello M. The Platelet-derived Growth Factor Controls c-myc Expression through a JNK- and AP-1-dependent Signaling Pathway. Journal of Biological Chemistry 2003;278:50024-30. [DOI: 10.1074/jbc.m308617200] [Cited by in Crossref: 42] [Cited by in F6Publishing: 24] [Article Influence: 2.2] [Reference Citation Analysis]
339 Sun M, Zhu M, Chen K, Nie X, Deng Q, Hazlett LD, Wu Y, Li M, Wu M, Huang X. TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway. Invest Ophthalmol Vis Sci 2013;54:3451-62. [PMID: 23611998 DOI: 10.1167/iovs.12-10938] [Cited by in Crossref: 37] [Cited by in F6Publishing: 39] [Article Influence: 4.1] [Reference Citation Analysis]
340 Tian F, Zang WD, Hou WH, Liu HT, Xue LX. Nuclear Factor-κB Signaling Pathway Constitutively Activated in EsophagealSquamous Cell Carcinoma Cell Lines and Inhibition of Growth of Cells by Small Interfering RNA. Acta Biochim Biophys Sin. 2006;38:318-326. [PMID: 16680372 DOI: 10.1111/j.1349-7006.2011.02025.x] [Cited by in Crossref: 46] [Cited by in F6Publishing: 39] [Article Influence: 2.9] [Reference Citation Analysis]
341 Kim JH, Kim SM, Pan C, Choi J, Lee JK. Evaluation of Anti-inflammatory Activities and Mechanisms of Microalga Phaeodactylum tricornutum. Journal of Applied Biological Chemistry 2013;56:61-7. [DOI: 10.3839/jabc.2013.011] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
342 Sadler TM, Achilleos M, Ragunathan S, Pitkin A, LaRocque J, Morin J, Annable R, Greenberger LM, Frost P, Zhang Y. Development and comparison of two nonradioactive kinase assays for I kappa B kinase. Anal Biochem 2004;326:106-13. [PMID: 14769342 DOI: 10.1016/j.ab.2003.11.021] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 0.9] [Reference Citation Analysis]
343 Sommermann TG, O'Neill K, Plas DR, Cahir-McFarland E. IKKβ and NF-κB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1. Cancer Res. 2011;71:7291-7300. [PMID: 21987722 DOI: 10.1158/0008-5472.can-11-1715] [Cited by in Crossref: 71] [Cited by in F6Publishing: 48] [Article Influence: 6.5] [Reference Citation Analysis]
344 Ye K. PIKE/nuclear PI 3-kinase signaling in preventing programmed cell death. J Cell Biochem 2005;96:463-72. [PMID: 16088938 DOI: 10.1002/jcb.20549] [Cited by in Crossref: 28] [Cited by in F6Publishing: 28] [Article Influence: 1.6] [Reference Citation Analysis]
345 Davies JM, Radford KJ, Begun J, Levesque JP, Winkler IG. Adhesion to E-selectin primes macrophages for activation through AKT and mTOR. Immunol Cell Biol 2021;99:622-39. [PMID: 33565143 DOI: 10.1111/imcb.12447] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
346 Zhang Y, Zhang L, Yan M, Zheng X. Inhibition of phosphatidylinositol 3-kinase causes cell death in rat osteoblasts through inactivation of Akt. Biomedicine & Pharmacotherapy 2007;61:277-84. [DOI: 10.1016/j.biopha.2007.02.014] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 0.7] [Reference Citation Analysis]
347 Douillette A, Bibeau-Poirier A, Gravel SP, Clément JF, Chénard V, Moreau P, Servant MJ. The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex. J Biol Chem 2006;281:13275-84. [PMID: 16513650 DOI: 10.1074/jbc.M512815200] [Cited by in Crossref: 52] [Cited by in F6Publishing: 30] [Article Influence: 3.3] [Reference Citation Analysis]
348 Chen YH, Lu Y, De Plaen IG, Wang LY, Tan XD. Transcription factor NF-kappaB signals antianoikic function of trefoil factor 3 on intestinal epithelial cells. Biochem Biophys Res Commun. 2000;274:576-582. [PMID: 10924320 DOI: 10.1006/bbrc.2000.3176] [Cited by in Crossref: 49] [Cited by in F6Publishing: 54] [Article Influence: 2.2] [Reference Citation Analysis]
349 Kim D, Chung J. Akt: Versatile Mediator of Cell Survival and Beyond. BMB Reports 2002;35:106-15. [DOI: 10.5483/bmbrep.2002.35.1.106] [Cited by in Crossref: 78] [Cited by in F6Publishing: 51] [Article Influence: 3.9] [Reference Citation Analysis]
350 Thomas PE, Peters-Golden M, White ES, Thannickal VJ, Moore BB. PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling. Am J Physiol Lung Cell Mol Physiol 2007;293:L417-28. [PMID: 17557799 DOI: 10.1152/ajplung.00489.2006] [Cited by in Crossref: 70] [Cited by in F6Publishing: 67] [Article Influence: 4.7] [Reference Citation Analysis]
351 Jost PJ, Ruland J. Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications. Blood 2007;109:2700-7. [PMID: 17119127 DOI: 10.1182/blood-2006-07-025809] [Cited by in Crossref: 293] [Cited by in F6Publishing: 259] [Article Influence: 19.5] [Reference Citation Analysis]
352 Peng F, Dhillon N, Callen S, Yao H, Bokhari S, Zhu X, Baydoun HH, Buch S. Platelet-derived growth factor protects neurons against gp120-mediated toxicity. J Neurovirol 2008;14:62-72. [PMID: 18300076 DOI: 10.1080/13550280701809084] [Cited by in Crossref: 33] [Cited by in F6Publishing: 37] [Article Influence: 2.4] [Reference Citation Analysis]
353 Bone H, Williams NA. Antigen-receptor cross-linking and lipopolysaccharide trigger distinct phosphoinositide 3-kinase-dependent pathways to NF-kappa B activation in primary B cells. Int Immunol 2001;13:807-16. [PMID: 11369709 DOI: 10.1093/intimm/13.6.807] [Cited by in Crossref: 33] [Cited by in F6Publishing: 34] [Article Influence: 1.6] [Reference Citation Analysis]
354 Horiguchi K, Arai S, Nishihara T, Nishikawa J. AIB1 promotes DNA replication by JNK repression and AKT activation during cellular stress. J Biochem 2006;140:409-19. [PMID: 16877447 DOI: 10.1093/jb/mvj167] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 0.6] [Reference Citation Analysis]
355 Hamidi A, Song J, Thakur N, Itoh S, Marcusson A, Bergh A, Heldin CH, Landström M. TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α. Sci Signal 2017;10:eaal4186. [PMID: 28676490 DOI: 10.1126/scisignal.aal4186] [Cited by in Crossref: 96] [Cited by in F6Publishing: 94] [Article Influence: 19.2] [Reference Citation Analysis]
356 Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature. 2000;406:86-90. [PMID: 10894547 DOI: 10.1038/35017574] [Cited by in Crossref: 1003] [Cited by in F6Publishing: 1010] [Article Influence: 45.6] [Reference Citation Analysis]
357 Yanagida M, Miura Y, Yagasaki K, Taoka M, Isobe T, Takahashi N. Matrix assisted laser desorption/ionization-time of flight-mass spectrometry analysis of proteins detected by anti-phosphotyrosine antibody on two-dimensional-gels of fibrolast cell lysates after tumor necrosis factor-α stimulation. Electrophoresis 2000;21:1890-8. [DOI: 10.1002/(sici)1522-2683(20000501)21:9<1890::aid-elps1890>3.0.co;2-7] [Cited by in Crossref: 41] [Cited by in F6Publishing: 7] [Article Influence: 1.9] [Reference Citation Analysis]
358 Fauzee NJS, Li Q, Wang Y, Pan J. Silencing Poly (ADP-Ribose) Glycohydrolase (PARG) Expression Inhibits Growth of Human Colon Cancer Cells In Vitro via PI3K/Akt/NFκ-B Pathway. Pathol Oncol Res 2012;18:191-9. [DOI: 10.1007/s12253-011-9428-1] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 1.5] [Reference Citation Analysis]
359 Koul D, Shen R, Shishodia S, Takada Y, Bhat KP, Reddy SA, Aggarwal BB, Yung WK. PTEN down regulates AP-1 and targets c-fos in human glioma cells via PI3-kinase/Akt pathway. Mol Cell Biochem 2007;300:77-87. [PMID: 17235455 DOI: 10.1007/s11010-006-9371-8] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 1.7] [Reference Citation Analysis]
360 Wu D, Cederbaum AI. Removal of Glutathione Produces Apoptosis and Necrosis in HepG2 Cells Overexpressing CYP2E1. Alcoholism Clin Exp Res 2001;25:619-28. [DOI: 10.1111/j.1530-0277.2001.tb02259.x] [Cited by in Crossref: 66] [Cited by in F6Publishing: 47] [Article Influence: 3.1] [Reference Citation Analysis]
361 Ceni C, Unsain N, Zeinieh MP, Barker PA. Neurotrophins in the regulation of cellular survival and death. Handb Exp Pharmacol 2014;220:193-221. [PMID: 24668474 DOI: 10.1007/978-3-642-45106-5_8] [Cited by in Crossref: 37] [Cited by in F6Publishing: 39] [Article Influence: 4.6] [Reference Citation Analysis]
362 Zhan Y, Liu R, Wang W, Li J, Ou Yang X, Zhang Y. Total saponins isolated from Radix et Rhizoma Leonticis suppresses tumor cells growth by regulation of PI3K/Akt/mTOR and p38 MAPK pathways. Environmental Toxicology and Pharmacology 2016;41:39-44. [DOI: 10.1016/j.etap.2015.10.008] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.7] [Reference Citation Analysis]
363 Lu DY, Tang CH, Yeh WL, Wong KL, Lin CP, Chen YH, Lai CH, Chen YF, Leung YM, Fu WM. SDF-1alpha up-regulates interleukin-6 through CXCR4, PI3K/Akt, ERK, and NF-kappaB-dependent pathway in microglia. Eur J Pharmacol 2009;613:146-54. [PMID: 19285061 DOI: 10.1016/j.ejphar.2009.03.001] [Cited by in Crossref: 91] [Cited by in F6Publishing: 89] [Article Influence: 7.0] [Reference Citation Analysis]
364 Vallée A, Lecarpentier Y. Curcumin and Endometriosis. Int J Mol Sci 2020;21:E2440. [PMID: 32244563 DOI: 10.3390/ijms21072440] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 6.5] [Reference Citation Analysis]
365 Santos M, Perez P, Segrelles C, Ruiz S, Jorcano JL, Paramio JM. Impaired NF-kappa B activation and increased production of tumor necrosis factor alpha in transgenic mice expressing keratin K10 in the basal layer of the epidermis. J Biol Chem 2003;278:13422-30. [PMID: 12566451 DOI: 10.1074/jbc.M208170200] [Cited by in Crossref: 19] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
366 Liu Z, Ouyang L, Peng H, Zhang WZ. Oridonin: targeting programmed cell death pathways as an anti-tumour agent. Cell Prolif 2012;45:499-507. [PMID: 23106297 DOI: 10.1111/j.1365-2184.2012.00849.x] [Cited by in Crossref: 44] [Cited by in F6Publishing: 37] [Article Influence: 4.9] [Reference Citation Analysis]
367 Zhang F, Cheng J, Hackett NR, Lam G, Shido K, Pergolizzi R, Jin DK, Crystal RG, Rafii S. Adenovirus E4 gene promotes selective endothelial cell survival and angiogenesis via activation of the vascular endothelial-cadherin/Akt signaling pathway. J Biol Chem 2004;279:11760-6. [PMID: 14660586 DOI: 10.1074/jbc.M312221200] [Cited by in Crossref: 36] [Cited by in F6Publishing: 22] [Article Influence: 1.9] [Reference Citation Analysis]
368 Gruber HE, Norton HJ, Hanley EN. Anti-apoptotic effects of IGF-1 and PDGF on human intervertebral disc cells in vitro. Spine (Phila Pa 1976). 2000;25:2153-2157. [PMID: 10973395 DOI: 10.1097/00007632-200009010-00002] [Cited by in Crossref: 168] [Cited by in F6Publishing: 150] [Article Influence: 7.6] [Reference Citation Analysis]
369 Yu L, Guo Y, Chang Z, Zhang D, Zhang S, Pei H, Pang J, Zhao ZJ, Chen Y. Bidirectional Interaction Between Cancer Cells and Platelets Provides Potential Strategies for Cancer Therapies. Front Oncol 2021;11:764119. [PMID: 34722319 DOI: 10.3389/fonc.2021.764119] [Reference Citation Analysis]
370 Timp W, Levchenko A, Feinberg AP. A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction. Cell Cycle 2009;8:383-90. [PMID: 19177016 DOI: 10.4161/cc.8.3.7542] [Cited by in Crossref: 27] [Cited by in F6Publishing: 19] [Article Influence: 2.1] [Reference Citation Analysis]
371 Hong J, Wang Y, Hu BC, Xu L, Liu JQ, Chen MH, Wang JZ, Han F, Zheng Y, Chen X, Li Q, Yang XH, Sun RH, Mo SJ. Transcriptional downregulation of microRNA-19a by ROS production and NF-κB deactivation governs resistance to oxidative stress-initiated apoptosis. Oncotarget 2017;8:70967-81. [PMID: 29050336 DOI: 10.18632/oncotarget.20235] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 2.8] [Reference Citation Analysis]
372 Weinstein N, Mendoza L, Álvarez-Buylla ER. A Computational Model of the Endothelial to Mesenchymal Transition. Front Genet 2020;11:40. [PMID: 32226439 DOI: 10.3389/fgene.2020.00040] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
373 Yang CH, Murti A, Pfeffer LM. Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival. J Biol Chem 2005;280:31530-6. [PMID: 16009713 DOI: 10.1074/jbc.M503120200] [Cited by in Crossref: 55] [Cited by in F6Publishing: 36] [Article Influence: 3.2] [Reference Citation Analysis]
374 Billie Au PY, Martin N, Chau H, Moemeni B, Chia M, Liu F, Minden M, Yeh W. The oncogene PDGF-B provides a key switch from cell death to survival induced by TNF. Oncogene 2005;24:3196-205. [DOI: 10.1038/sj.onc.1208516] [Cited by in Crossref: 17] [Cited by in F6Publishing: 18] [Article Influence: 1.0] [Reference Citation Analysis]
375 Volanti C, Hendrickx N, Van Lint J, Matroule JY, Agostinis P, Piette J. Distinct transduction mechanisms of cyclooxygenase 2 gene activation in tumour cells after photodynamic therapy. Oncogene 2005;24:2981-91. [PMID: 15735712 DOI: 10.1038/sj.onc.1208481] [Cited by in Crossref: 28] [Cited by in F6Publishing: 27] [Article Influence: 1.6] [Reference Citation Analysis]
376 Grünwald V, Hidalgo M. Developing inhibitors of the epidermal growth factor receptor for cancer treatment. J Natl Cancer Inst 2003;95:851-67. [PMID: 12813169 DOI: 10.1093/jnci/95.12.851] [Cited by in Crossref: 252] [Cited by in F6Publishing: 206] [Article Influence: 13.3] [Reference Citation Analysis]
377 Rössig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM, Dimmeler S. Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol. 2001;21:5644-5657. [PMID: 11463845 DOI: 10.1128/mcb.21.16.5644-5657.2001] [Cited by in Crossref: 242] [Cited by in F6Publishing: 112] [Article Influence: 11.5] [Reference Citation Analysis]
378 Zhang HM, Yuan J, Cheung P, Luo H, Yanagawa B, Chau D, Stephan-tozy N, Wong BW, Zhang J, Wilson JE, Mcmanus BM, Yang D. Overexpression of Interferon-γ-inducible GTPase Inhibits Coxsackievirus B3-induced Apoptosis through the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway and Inhibition of Viral Replication. Journal of Biological Chemistry 2003;278:33011-9. [DOI: 10.1074/jbc.m305352200] [Cited by in Crossref: 49] [Cited by in F6Publishing: 21] [Article Influence: 2.6] [Reference Citation Analysis]
379 Zhande R, Karsan A. Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL. Am J Physiol Heart Circ Physiol 2007;292:H2467-74. [PMID: 17237249 DOI: 10.1152/ajpheart.00649.2006] [Cited by in Crossref: 21] [Cited by in F6Publishing: 21] [Article Influence: 1.4] [Reference Citation Analysis]
380 Tsuchiya K, Tanaka J, Shuiqing Y, Welch CL, DePinho RA, Tabas I, Tall AR, Goldberg IJ, Accili D. FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metab. 2012;15:372-381. [PMID: 22405072 DOI: 10.1016/j.cmet.2012.01.018] [Cited by in Crossref: 110] [Cited by in F6Publishing: 103] [Article Influence: 11.0] [Reference Citation Analysis]
381 Wu GC, Liao WI, Wu SY, Pao HP, Tang SE, Li MH, Huang KL, Chu SJ. Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats. Respir Res 2017;18:71. [PMID: 28438162 DOI: 10.1186/s12931-017-0557-2] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 2.8] [Reference Citation Analysis]
382 Liu Q, White LR, Clark SA, Heffner DJ, Winston BW, Tibbles LA, Muruve DA. Akt/protein kinase B activation by adenovirus vectors contributes to NFkappaB-dependent CXCL10 expression. J Virol 2005;79:14507-15. [PMID: 16282450 DOI: 10.1128/JVI.79.23.14507-14515.2005] [Cited by in Crossref: 23] [Cited by in F6Publishing: 18] [Article Influence: 1.4] [Reference Citation Analysis]
383 Jordà M, Olmeda D, Vinyals A, Valero E, Cubillo E, Llorens A, Cano A, Fabra A. Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. J Cell Sci 2005;118:3371-85. [PMID: 16079281 DOI: 10.1242/jcs.02465] [Cited by in Crossref: 162] [Cited by in F6Publishing: 157] [Article Influence: 9.5] [Reference Citation Analysis]
384 Lee SH, Byun JS, Kong PJ, Lee HJ, Kim DK, Kim HS, Sohn JH, Lee JJ, Lim SY, Chun W, Kim SS. Inhibition of eNOS/sGC/PKG Pathway Decreases Akt Phosphorylation Induced by Kainic Acid in Mouse Hippocampus. Korean J Physiol Pharmacol 2010;14:37-43. [PMID: 20221278 DOI: 10.4196/kjpp.2010.14.1.37] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.7] [Reference Citation Analysis]
385 Shankar E, Vykhovanets EV, Vykhovanets OV, Maclennan GT, Singh R, Bhaskaran N, Shukla S, Gupta S. High-fat diet activates pro-inflammatory response in the prostate through association of Stat-3 and NF-κB. Prostate 2012;72:233-43. [PMID: 21604287 DOI: 10.1002/pros.21425] [Cited by in Crossref: 43] [Cited by in F6Publishing: 43] [Article Influence: 3.9] [Reference Citation Analysis]
386 Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell. 2007;129:1261-1274. [PMID: 17604717 DOI: 10.1016/j.cell.2007.06.009] [Cited by in Crossref: 3936] [Cited by in F6Publishing: 3850] [Article Influence: 262.4] [Reference Citation Analysis]
387 Adeniran C, Hamelberg D. Redox-Specific Allosteric Modulation of the Conformational Dynamics of κB DNA by Pirin in the NF-κB Supramolecular Complex. Biochemistry 2017;56:5002-10. [DOI: 10.1021/acs.biochem.7b00528] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
388 Qin X, Zhang Z, Xu H, Wu Y. Notch signaling protects retina from nuclear factor-κB- and poly-ADP-ribose-polymerase-mediated apoptosis under high-glucose stimulation. Acta Biochim Biophys Sin (Shanghai) 2011;43:703-11. [PMID: 21813561 DOI: 10.1093/abbs/gmr069] [Cited by in Crossref: 23] [Cited by in F6Publishing: 20] [Article Influence: 2.1] [Reference Citation Analysis]
389 Nguyen DM, Chen GA, Reddy R, Tsai W, Schrump WD, Cole G, Schrump DS. Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway. J Thorac Cardiovasc Surg. 2004;127:365-375. [PMID: 14762343 DOI: 10.1016/j.jtcvs.2003.09.033] [Cited by in Crossref: 40] [Cited by in F6Publishing: 35] [Article Influence: 2.2] [Reference Citation Analysis]
390 Molgat AS, Gagnon A, Sorisky A. Macrophage-induced preadipocyte survival depends on signaling through Akt, ERK1/2, and reactive oxygen species. Exp Cell Res 2011;317:521-30. [PMID: 21056559 DOI: 10.1016/j.yexcr.2010.10.024] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
391 Yang JY, Della-Fera MA, Hausman DB, Baile CA. Enhancement of ajoene-induced apoptosis by conjugated linoleic acid in 3T3-L1 adipocytes. Apoptosis 2007;12:1117-28. [PMID: 17318368 DOI: 10.1007/s10495-006-0043-7] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 0.9] [Reference Citation Analysis]
392 Tsai M, Lai C, Chang Y, Chen W, Ho C, Pan M. Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis. Food Funct 2012;3:1185. [DOI: 10.1039/c2fo30105a] [Cited by in Crossref: 37] [Cited by in F6Publishing: 32] [Article Influence: 3.7] [Reference Citation Analysis]
393 Croft M, So T, Duan W, Soroosh P. The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol Rev 2009;229:173-91. [PMID: 19426222 DOI: 10.1111/j.1600-065X.2009.00766.x] [Cited by in Crossref: 291] [Cited by in F6Publishing: 175] [Article Influence: 22.4] [Reference Citation Analysis]
394 Bandyopadhaya A, Bhowmick S, Chaudhuri K. Activation of proinflammatory response in human intestinal epithelial cells following Vibrio cholerae infection through PI3K/Akt pathway. Can J Microbiol 2009;55:1310-8. [PMID: 19940940 DOI: 10.1139/w09-093] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.7] [Reference Citation Analysis]
395 Tiwari N, Gheldof A, Tatari M, Christofori G. EMT as the ultimate survival mechanism of cancer cells. Seminars in Cancer Biology 2012;22:194-207. [DOI: 10.1016/j.semcancer.2012.02.013] [Cited by in Crossref: 306] [Cited by in F6Publishing: 280] [Article Influence: 30.6] [Reference Citation Analysis]
396 Manson MM, Howells LM, Hudson EA. Signalling Pathways as Targets in Cancer Prevention. In: Vainio HU, Hietanen EK, editors. Mechanisms in Carcinogenesis and Cancer Prevention. Berlin: Springer Berlin Heidelberg; 2003. pp. 41-56. [DOI: 10.1007/978-3-662-08602-5_4] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
397 Hsiung S, Tin A, Tamir H, Franke TF, Liu K. Inhibition of 5‐HT 1A receptor‐dependent cell survival by cAMP/protein kinase A: Role of protein phosphatase 2A and Bax. J Neurosci Res 2008;86:2326-38. [DOI: 10.1002/jnr.21676] [Cited by in Crossref: 16] [Cited by in F6Publishing: 18] [Article Influence: 1.1] [Reference Citation Analysis]
398 Samimi M, Pourhanifeh MH, Mehdizadehkashi A, Eftekhar T, Asemi Z. The role of inflammation, oxidative stress, angiogenesis, and apoptosis in the pathophysiology of endometriosis: Basic science and new insights based on gene expression. J Cell Physiol 2019;234:19384-92. [PMID: 31004368 DOI: 10.1002/jcp.28666] [Cited by in Crossref: 32] [Cited by in F6Publishing: 32] [Article Influence: 10.7] [Reference Citation Analysis]
399 Miller-Jensen K, Janes KA, Wong YL, Griffith LG, Lauffenburger DA. Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis. J Cell Sci 2006;119:3788-98. [PMID: 16940353 DOI: 10.1242/jcs.03102] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 1.3] [Reference Citation Analysis]
400 Han DW, Jung DY, Park JC, Cho HH, Hyon SH, Han DK. Underlying mechanism for suppression of vascular smooth muscle cells by green tea polyphenol EGCG released from biodegradable polymers for stent application. J Biomed Mater Res A 2010;95:424-33. [PMID: 20648542 DOI: 10.1002/jbm.a.32870] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 0.9] [Reference Citation Analysis]
401 Gnesutta N, Minden A. Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4. Mol Cell Biol. 2003;23:7838-7848. [PMID: 14560027 DOI: 10.1128/mcb.23.21.7838-7848.2003] [Cited by in Crossref: 74] [Cited by in F6Publishing: 37] [Article Influence: 3.9] [Reference Citation Analysis]
402 Shiojima I, Walsh K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ Res 2002;90:1243-50. [PMID: 12089061 DOI: 10.1161/01.res.0000022200.71892.9f] [Cited by in Crossref: 697] [Cited by in F6Publishing: 304] [Article Influence: 34.9] [Reference Citation Analysis]
403 Hua F, Ma J, Ha T, Kelley JL, Kao RL, Schweitzer JB, Kalbfleisch JH, Williams DL, Li C. Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice. Brain Res 2009;1262:100-8. [PMID: 19401158 DOI: 10.1016/j.brainres.2009.01.018] [Cited by in Crossref: 98] [Cited by in F6Publishing: 102] [Article Influence: 7.5] [Reference Citation Analysis]
404 Hwang IK, Yoo K, Kim DW, Lee B, Kang T, Choi SY, Han BH, Kim JS, Won MH. Ischemia-related changes of glial-derived neurotrophic factor and phosphatidylinositol 3-kinase in the hippocampus: Their possible correlation in astrocytes. Brain Research 2006;1072:215-23. [DOI: 10.1016/j.brainres.2005.12.012] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 0.8] [Reference Citation Analysis]
405 Puvvada SD, Funkhouser WK, Greene K, Deal A, Chu H, Baldwin AS, Tepper JE, O'Neil BH. NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer. Oncology 2010;78:181-8. [PMID: 20414006 DOI: 10.1159/000313697] [Cited by in Crossref: 53] [Cited by in F6Publishing: 49] [Article Influence: 4.4] [Reference Citation Analysis]
406 Yu Y, Fu X, Ran Q, Yang K, Wen Y, Li H, Wang F. Globularifolin exerts anticancer effects on glioma U87 cells through inhibition of Akt/mTOR and MEK/ERK signaling pathways in vitro and inhibits tumor growth in vivo. Biochimie 2017;142:144-51. [PMID: 28912095 DOI: 10.1016/j.biochi.2017.09.005] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.6] [Reference Citation Analysis]
407 Song I, Jeong YJ, Jeong SH, Kim HK, Ha N, Shin M, Ko KS, Rhee BD, Shim S, Jang S, Han J. Pharmacologic inhibition of AKT leads to cell death in relapsed multiple myeloma. Cancer Letters 2018;432:205-15. [DOI: 10.1016/j.canlet.2018.06.020] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
408 Cahill KE, Morshed RA, Yamini B. Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy. Neuro Oncol 2016;18:329-39. [PMID: 26534766 DOI: 10.1093/neuonc/nov265] [Cited by in Crossref: 54] [Cited by in F6Publishing: 55] [Article Influence: 7.7] [Reference Citation Analysis]
409 Jiang C, Lin X. Regulation of NF-κB by the CARD proteins. Immunol Rev 2012;246:141-53. [PMID: 22435552 DOI: 10.1111/j.1600-065X.2012.01110.x] [Cited by in Crossref: 58] [Cited by in F6Publishing: 35] [Article Influence: 5.8] [Reference Citation Analysis]
410 Babaev VR, Chew JD, Ding L, Davis S, Breyer MD, Breyer RM, Oates JA, Fazio S, Linton MF. Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis. Cell Metab 2008;8:492-501. [PMID: 19041765 DOI: 10.1016/j.cmet.2008.09.005] [Cited by in Crossref: 77] [Cited by in F6Publishing: 73] [Article Influence: 5.9] [Reference Citation Analysis]
411 Cheon H, Sun YK, Yu SJ, Lee YH, Ji JD, Song GG, Lee JH, Kim MK, Sohn J. Platelet-derived growth factor-AA increases IL-1beta and IL-8 expression and activates NF-kappaB in rheumatoid fibroblast-like synoviocytes. Scand J Immunol 2004;60:455-62. [PMID: 15541037 DOI: 10.1111/j.0300-9475.2004.01505.x] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 1.0] [Reference Citation Analysis]
412 Jaspers I, Zhang W, Fraser A, Samet JM, Reed W. Hydrogen peroxide has opposing effects on IKK activity and IkappaBalpha breakdown in airway epithelial cells. Am J Respir Cell Mol Biol 2001;24:769-77. [PMID: 11415944 DOI: 10.1165/ajrcmb.24.6.4344] [Cited by in Crossref: 75] [Cited by in F6Publishing: 73] [Article Influence: 3.6] [Reference Citation Analysis]
413 Rauch BH, Weber A, Braun M, Zimmermann N, Schrör K. PDGF-induced Akt phosphorylation does not activate NF-κB in human vascular smooth muscle cells and fibroblasts. FEBS Letters 2000;481:3-7. [DOI: 10.1016/s0014-5793(00)01957-8] [Cited by in Crossref: 40] [Cited by in F6Publishing: 10] [Article Influence: 1.8] [Reference Citation Analysis]
414 O'gorman D, Cotter T. Molecular signals in anti-apoptotic survival pathways. Leukemia 2001;15:21-34. [DOI: 10.1038/sj.leu.2401998] [Cited by in Crossref: 50] [Cited by in F6Publishing: 50] [Article Influence: 2.4] [Reference Citation Analysis]
415 Thakkar A, Sutaria D, Grandhi BK, Wang J, Prabhu S. The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer. Oncol Rep 2013;29:1671-7. [PMID: 23404329 DOI: 10.3892/or.2013.2276] [Cited by in Crossref: 25] [Cited by in F6Publishing: 21] [Article Influence: 2.8] [Reference Citation Analysis]
416 Chen J, Hsiao G, Lee A, Wu C, Yen M. Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway. Biochemical Pharmacology 2004;67:1337-45. [DOI: 10.1016/j.bcp.2003.12.015] [Cited by in Crossref: 50] [Cited by in F6Publishing: 50] [Article Influence: 2.8] [Reference Citation Analysis]
417 Kanayama S, Yamada Y, Onogi A, Shigetomi H, Ueda S, Tsuji Y, Haruta S, Kawaguchi R, Yoshida S, Sakata M, Sado T, Kitanaka T, Oi H, Yagyu T, Kobayashi H. Bikunin suppresses expression of pro-inflammatory cytokines induced by lipopolysaccharide in neutrophils. J Endotoxin Res 2007;13:369-76. [PMID: 18182464 DOI: 10.1177/0968051907086464] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
418 Yan X, Shen H, Jiang H, Zhang C, Hu D, Wang J, Wu X. External Qi of Yan Xin Qigong differentially regulates the Akt and extracellular signal-regulated kinase pathways and is cytotoxic to cancer cells but not to normal cells. Int J Biochem Cell Biol 2006;38:2102-13. [PMID: 16893670 DOI: 10.1016/j.biocel.2006.06.002] [Cited by in Crossref: 24] [Cited by in F6Publishing: 16] [Article Influence: 1.5] [Reference Citation Analysis]
419 Nakamura H, Aoki H, Hino O, Moriyama M. HCV core protein promotes heparin binding EGF-like growth factor expression and activates Akt. Hepatol Res 2011;41:455-62. [PMID: 21418450 DOI: 10.1111/j.1872-034X.2011.00792.x] [Cited by in Crossref: 25] [Cited by in F6Publishing: 16] [Article Influence: 2.3] [Reference Citation Analysis]
420 Dardik A, Chen L, Frattini J, Asada H, Aziz F, Kudo FA, Sumpio BE. Differential effects of orbital and laminar shear stress on endothelial cells. Journal of Vascular Surgery 2005;41:869-80. [DOI: 10.1016/j.jvs.2005.01.020] [Cited by in Crossref: 195] [Cited by in F6Publishing: 172] [Article Influence: 11.5] [Reference Citation Analysis]
421 Albanese C, Wu K, D'Amico M, Jarrett C, Joyce D, Hughes J, Hulit J, Sakamaki T, Fu M, Ben-Ze'ev A, Bromberg JF, Lamberti C, Verma U, Gaynor RB, Byers SW, Pestell RG. IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Mol Biol Cell 2003;14:585-99. [PMID: 12589056 DOI: 10.1091/mbc.02-06-0101] [Cited by in Crossref: 111] [Cited by in F6Publishing: 107] [Article Influence: 5.8] [Reference Citation Analysis]
422 Astoul E, Laurence AD, Totty N, Beer S, Alexander DR, Cantrell DA. Approaches to Define Antigen Receptor-induced Serine Kinase Signal Transduction Pathways. Journal of Biological Chemistry 2003;278:9267-75. [DOI: 10.1074/jbc.m211252200] [Cited by in Crossref: 27] [Cited by in F6Publishing: 12] [Article Influence: 1.4] [Reference Citation Analysis]
423 Shen GN, Li J, Jin YH, Sun HN, Hao YY, Jin MH, Liu R, Li WL, Zhang YQ, Yu JB, Yu NN, Wang WD, Yu LY, Kim JS, Kwon T, Han YH. The compound 2-benzylthio-5,8-dimethoxynaphthalene-1,4-dione leads to apoptotic cell death by increasing the cellular reactive oxygen species levels in Ras-mutated liver cancer cells. Exp Ther Med 2020;20:82. [PMID: 32968439 DOI: 10.3892/etm.2020.9209] [Reference Citation Analysis]
424 Miraglia AG, Travaglione S, Meschini S, Falzano L, Matarrese P, Quaranta MG, Viora M, Fiorentini C, Fabbri A. Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2. Mol Biol Cell 2007;18:2735-44. [PMID: 17507655 DOI: 10.1091/mbc.e06-10-0910] [Cited by in Crossref: 39] [Cited by in F6Publishing: 27] [Article Influence: 2.6] [Reference Citation Analysis]
425 Tamura A, Matsunobu T, Tamura R, Kawauchi S, Sato S, Shiotani A. Photobiomodulation rescues the cochlea from noise-induced hearing loss via upregulating nuclear factor κB expression in rats. Brain Res 2016;1646:467-74. [PMID: 27342816 DOI: 10.1016/j.brainres.2016.06.031] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 1.3] [Reference Citation Analysis]
426 Arunkumar R, Sharmila G, Elumalai P, Senthilkumar K, Banudevi S, Gunadharini DN, Benson CS, Daisy P, Arunakaran J. Effect of diallyl disulfide on insulin-like growth factor signaling molecules involved in cell survival and proliferation of human prostate cancer cells in vitro and in silico approach through docking analysis. Phytomedicine 2012;19:912-23. [PMID: 22739413 DOI: 10.1016/j.phymed.2012.04.009] [Cited by in Crossref: 24] [Cited by in F6Publishing: 20] [Article Influence: 2.4] [Reference Citation Analysis]
427 Ghatak S, Misra S, Moreno-Rodrigue RA, Hascall VC, Leone GW, Markwald RR. Periostin/β1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization. Biochim Biophys Acta Gen Subj 2019;1863:813-29. [PMID: 30742951 DOI: 10.1016/j.bbagen.2018.12.015] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 1.3] [Reference Citation Analysis]
428 Sephton CF, Mousseau DD. Dephosphorylation of Akt in C6 cells grown in serum-free conditions corresponds with redistribution of p85/PI3K to the nucleus. J Neurosci Res 2008;86:675-82. [PMID: 17918740 DOI: 10.1002/jnr.21516] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
429 Vandermoere F, El Yazidi-Belkoura I, Adriaenssens E, Lemoine J, Hondermarck H. The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-kappaB activation induced via interaction between Akt and IkappaB kinase-beta in breast cancer cells. Oncogene. 2005;24:5482-5491. [PMID: 15856005 DOI: 10.1038/sj.onc.1208713] [Cited by in Crossref: 68] [Cited by in F6Publishing: 65] [Article Influence: 4.0] [Reference Citation Analysis]
430 Wong SC, Chew WK, Tan JE, Melendez AJ, Francis F, Lam KP. Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cells. J Biol Chem 2002;277:30707-15. [PMID: 12070149 DOI: 10.1074/jbc.M202460200] [Cited by in Crossref: 71] [Cited by in F6Publishing: 30] [Article Influence: 3.6] [Reference Citation Analysis]
431 Achiwa Y, Hasegawa K, Udagawa Y. Regulation of the phosphatidylinositol 3-kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells. Biosci Biotechnol Biochem. 2007;71:31-37. [PMID: 17213663 DOI: 10.1271/bbb.60288] [Cited by in Crossref: 35] [Cited by in F6Publishing: 32] [Article Influence: 2.3] [Reference Citation Analysis]
432 Zhang B, Spandau DF, Roman A. E5 protein of human papillomavirus type 16 protects human foreskin keratinocytes from UV B-irradiation-induced apoptosis. J Virol 2002;76:220-31. [PMID: 11739687 DOI: 10.1128/jvi.76.1.220-231.2002] [Cited by in Crossref: 70] [Cited by in F6Publishing: 30] [Article Influence: 3.5] [Reference Citation Analysis]
433 Yin X, Zhang Q, Miao B, Zhang G. Neuroprotective effects of preconditioning ischaemia on ischaemic brain injury through inhibition of mixed-lineage kinase 3 via NMDA receptor-mediated Akt1 activation. J Neurochem 2005;93:1021-9. [DOI: 10.1111/j.1471-4159.2005.03096.x] [Cited by in Crossref: 33] [Cited by in F6Publishing: 33] [Article Influence: 1.9] [Reference Citation Analysis]
434 Watanabe S, Murakami T, Nakamura T, Morimoto C, Arai K. Human GM-CSF induces HIV-1 LTR by multiple signalling pathways. Biochimie 2002;84:633-42. [DOI: 10.1016/s0300-9084(02)01433-5] [Cited by in Crossref: 5] [Article Influence: 0.3] [Reference Citation Analysis]
435 Russell S, Eley H, Wyke S, Tisdale M. Involvement of phosphoinositide 3-kinase and Akt in the induction of muscle protein degradation by proteolysis-inducing factor. Biochemical Journal 2008;409:751-9. [DOI: 10.1042/bj20070688] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
436 Rahman MA, Amin AR, Wang D, Koenig L, Nannapaneni S, Chen Z, Wang Z, Sica G, Deng X, Chen ZG, Shin DM. RRM2 regulates Bcl-2 in head and neck and lung cancers: a potential target for cancer therapy. Clin Cancer Res 2013;19:3416-28. [PMID: 23719266 DOI: 10.1158/1078-0432.CCR-13-0073] [Cited by in Crossref: 60] [Cited by in F6Publishing: 42] [Article Influence: 6.7] [Reference Citation Analysis]
437 Storz P, Toker A. Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway. EMBO J 2003;22:109-20. [PMID: 12505989 DOI: 10.1093/emboj/cdg009] [Cited by in Crossref: 245] [Cited by in F6Publishing: 234] [Article Influence: 12.9] [Reference Citation Analysis]
438 Barton ES, Forrest JC, Connolly JL, Chappell JD, Liu Y, Schnell FJ, Nusrat A, Parkos CA, Dermody TS. Junction adhesion molecule is a receptor for reovirus. Cell. 2001;104:441-451. [PMID: 11239401 DOI: 10.1016/s0092-8674(01)00231-8] [Cited by in Crossref: 474] [Cited by in F6Publishing: 255] [Article Influence: 22.6] [Reference Citation Analysis]
439 Hazra S, Peebles KA, Sharma S, Mao JT, Dubinett SM. The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer. PPAR Res 2008;2008:790568. [PMID: 18769553 DOI: 10.1155/2008/790568] [Cited by in Crossref: 21] [Cited by in F6Publishing: 21] [Article Influence: 1.9] [Reference Citation Analysis]
440 Rani MRS, Hibbert L, Sizemore N, Stark GR, Ransohoff RM. Requirement of Phosphoinositide 3-Kinase and Akt for Interferon-β-mediated Induction of the β-R1(SCYB11) Gene. Journal of Biological Chemistry 2002;277:38456-61. [DOI: 10.1074/jbc.m203204200] [Cited by in Crossref: 33] [Cited by in F6Publishing: 13] [Article Influence: 1.7] [Reference Citation Analysis]
441 Tai YT, Podar K, Mitsiades N, Lin B, Mitsiades C, Gupta D, Akiyama M, Catley L, Hideshima T, Munshi NC, Treon SP, Anderson KC. CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling. Blood 2003;101:2762-9. [PMID: 12433678 DOI: 10.1182/blood-2002-09-2813] [Cited by in Crossref: 88] [Cited by in F6Publishing: 73] [Article Influence: 4.4] [Reference Citation Analysis]
442 Mourkioti F, Kratsios P, Luedde T, Song YH, Delafontaine P, Adami R, Parente V, Bottinelli R, Pasparakis M, Rosenthal N. Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J Clin Invest. 2006;116:2945-2954. [PMID: 17080195 DOI: 10.1172/jci28721] [Cited by in Crossref: 218] [Cited by in F6Publishing: 135] [Article Influence: 13.6] [Reference Citation Analysis]
443 Xu L, Zhang L, Bertucci AM, Pope RM, Datta SK. Apigenin, a dietary flavonoid, sensitizes human T cells for activation-induced cell death by inhibiting PKB/Akt and NF-kappaB activation pathway. Immunol Lett 2008;121:74-83. [PMID: 18812189 DOI: 10.1016/j.imlet.2008.08.004] [Cited by in Crossref: 32] [Cited by in F6Publishing: 32] [Article Influence: 2.3] [Reference Citation Analysis]
444 Krishnamurthy S, Basu A. Regulation of IKKε Expression by Akt2 Isoform. Genes Cancer 2011;2:1044-50. [PMID: 22737270 DOI: 10.1177/1947601912444604] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
445 Milisav I, Poljšak B, Ribarič S. Reduced risk of apoptosis: mechanisms of stress responses. Apoptosis 2017;22:265-83. [DOI: 10.1007/s10495-016-1317-3] [Cited by in Crossref: 22] [Cited by in F6Publishing: 23] [Article Influence: 3.7] [Reference Citation Analysis]
446 Miller YI. Toll-like receptors and atherosclerosis: oxidized LDL as an endogenous Toll-like receptor ligand. Future Cardiol 2005;1:785-92. [PMID: 19804052 DOI: 10.2217/14796678.1.6.785] [Cited by in Crossref: 22] [Cited by in F6Publishing: 21] [Article Influence: 1.8] [Reference Citation Analysis]
447 Huwait EA, Saddeek SY, Al-Massabi RF, Almowallad SJ, Pushparaj PN, Kalamegam G. Antiatherogenic Effects of Quercetin in the THP-1 Macrophage Model In Vitro, With Insights Into Its Signaling Mechanisms Using In Silico Analysis. Front Pharmacol 2021;12:698138. [PMID: 34385920 DOI: 10.3389/fphar.2021.698138] [Reference Citation Analysis]
448 Mercurio L, Morelli M, Scarponi C, Scaglione GL, Pallotta S, Albanesi C, Madonna S. PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis. Cells 2021;10:2636. [PMID: 34685616 DOI: 10.3390/cells10102636] [Reference Citation Analysis]
449 Sarkar A, Möller S, Bhattacharyya A, Behnen M, Rupp J, van Zandbergen G, Solbach W, Laskay T. Mechanisms of apoptosis inhibition in Chlamydia pneumoniae-infected neutrophils. Int J Med Microbiol 2015;305:493-500. [PMID: 26005182 DOI: 10.1016/j.ijmm.2015.04.006] [Cited by in Crossref: 21] [Cited by in F6Publishing: 20] [Article Influence: 3.0] [Reference Citation Analysis]
450 Lawlor MA, Rotwein P. Coordinate control of muscle cell survival by distinct insulin-like growth factor activated signaling pathways. J Cell Biol 2000;151:1131-40. [PMID: 11121430 DOI: 10.1083/jcb.151.6.1131] [Cited by in Crossref: 59] [Cited by in F6Publishing: 58] [Article Influence: 2.8] [Reference Citation Analysis]
451 Montaseri A, Busch F, Mobasheri A, Buhrmann C, Aldinger C, Rad JS, Shakibaei M. IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway. PLoS One 2011;6:e28663. [PMID: 22194879 DOI: 10.1371/journal.pone.0028663] [Cited by in Crossref: 115] [Cited by in F6Publishing: 113] [Article Influence: 10.5] [Reference Citation Analysis]
452 Van Stry M, McLaughlin KA, Ataliotis P, Symes K. The mitochondrial-apoptotic pathway is triggered in Xenopus mesoderm cells deprived of PDGF receptor signaling during gastrulation. Dev Biol 2004;268:232-42. [PMID: 15031119 DOI: 10.1016/j.ydbio.2003.12.030] [Cited by in Crossref: 14] [Cited by in F6Publishing: 15] [Article Influence: 0.8] [Reference Citation Analysis]
453 Gundogdu G, Tosun M, Morhardt D, Gheinani AH, Algarrahi K, Yang X, Costa K, Alegria CG, Adam RM, Yang W, Mauney JR. Molecular mechanisms of esophageal epithelial regeneration following repair of surgical defects with acellular silk fibroin grafts. Sci Rep 2021;11:7086. [PMID: 33782465 DOI: 10.1038/s41598-021-86511-9] [Reference Citation Analysis]
454 Chung S, Jin Y, Han B, Qu Y, Gao B, Giuliano AE, Cui X. Identification of EGF-NF-κB-FOXC1 signaling axis in basal-like breast cancer. Cell Commun Signal 2017;15:22. [PMID: 28629477 DOI: 10.1186/s12964-017-0180-3] [Cited by in Crossref: 14] [Cited by in F6Publishing: 17] [Article Influence: 2.8] [Reference Citation Analysis]
455 Wang L, Yao J, Sun H, Sun R, Chang S, Yang Y, Song T, Huang C. miR-302b suppresses cell invasion and metastasis by directly targeting AKT2 in human hepatocellular carcinoma cells. Tumour Biol 2016;37:847-55. [PMID: 26254095 DOI: 10.1007/s13277-015-3330-5] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 2.3] [Reference Citation Analysis]
456 Harada N, Hatano E, Koizumi N, Nitta T, Yoshida M, Yamamoto N, Brenner DA, Yamaoka Y. Akt activation protects rat liver from ischemia/reperfusion injury1. Journal of Surgical Research 2004;121:159-70. [DOI: 10.1016/j.jss.2004.04.016] [Cited by in Crossref: 35] [Cited by in F6Publishing: 38] [Article Influence: 1.9] [Reference Citation Analysis]
457 Canicio J, Ruiz-lozano P, Carrasco M, Palacı́n M, Chien K, Zorzano A, Kaliman P. Nuclear Factor κB-inducing Kinase and IκB Kinase-α Signal Skeletal Muscle Cell Differentiation. Journal of Biological Chemistry 2001;276:20228-33. [DOI: 10.1074/jbc.m100718200] [Cited by in Crossref: 29] [Cited by in F6Publishing: 10] [Article Influence: 1.4] [Reference Citation Analysis]
458 Liou JS, Chen JS, Faller DV. Characterization of p21Ras-mediated apoptosis induced by protein kinase C inhibition and application to human tumor cell lines. J Cell Physiol 2004;198:277-94. [DOI: 10.1002/jcp.10409] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 0.8] [Reference Citation Analysis]
459 Ivanov VN, Ronai Z. p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression. Oncogene. 2000;19:3003-3012. [PMID: 10871852 DOI: 10.1038/sj.onc.1203602] [Cited by in Crossref: 97] [Cited by in F6Publishing: 91] [Article Influence: 4.4] [Reference Citation Analysis]
460 Lee SO, Lou W, Nadiminty N, Lin X, Gao AC. Requirement for NF-κB in interleukin-4-induced androgen receptor activation in prostate cancer cells. Prostate 2005;64:160-7. [DOI: 10.1002/pros.20218] [Cited by in Crossref: 49] [Cited by in F6Publishing: 42] [Article Influence: 2.9] [Reference Citation Analysis]
461 Choi J, Park H, Kim H, Kim SY, Lee JE, Choi Y, Chun M, Chung J, Lee M. Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia. Cell Tissue Res 2005;319:359-66. [DOI: 10.1007/s00441-004-1033-0] [Cited by in Crossref: 24] [Cited by in F6Publishing: 24] [Article Influence: 1.4] [Reference Citation Analysis]
462 Kimura A, Ohmichi M, Kawagoe J, Kyo S, Mabuchi S, Takahashi T, Ohshima C, Arimoto-Ishida E, Nishio Y, Inoue M. Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines. Oncogene. 2004;23:4505-4515. [PMID: 15048073 DOI: 10.1038/sj.onc.1207582] [Cited by in Crossref: 95] [Cited by in F6Publishing: 92] [Article Influence: 5.3] [Reference Citation Analysis]
463 Vallée A, Vallée JN, Le Blanche A, Lecarpentier Y. PPARγ Agonists: Emergent Therapy in Endometriosis. Pharmaceuticals (Basel) 2021;14:543. [PMID: 34204039 DOI: 10.3390/ph14060543] [Reference Citation Analysis]
464 Cox AD, Der CJ. The dark side of Ras: regulation of apoptosis. Oncogene. 2003;22:8999-9006. [PMID: 14663478 DOI: 10.1038/sj.onc.1207111] [Cited by in Crossref: 308] [Cited by in F6Publishing: 292] [Article Influence: 17.1] [Reference Citation Analysis]
465 Roux PP, Bhakar AL, Kennedy TE, Barker PA. The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. J Biol Chem 2001;276:23097-104. [PMID: 11312266 DOI: 10.1074/jbc.M011520200] [Cited by in Crossref: 97] [Cited by in F6Publishing: 43] [Article Influence: 4.6] [Reference Citation Analysis]
466 Kind M, Klukowska-Rötzler J, Berezowska S, Arcaro A, Charles RP. Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis. PLoS One 2017;12:e0187308. [PMID: 29088297 DOI: 10.1371/journal.pone.0187308] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.4] [Reference Citation Analysis]
467 Cross TG, Scheel-Toellner D, Henriquez NV, Deacon E, Salmon M, Lord JM. Serine/threonine protein kinases and apoptosis. Exp Cell Res. 2000;256:34-41. [PMID: 10739649 DOI: 10.1006/excr.2000.4836] [Cited by in Crossref: 497] [Cited by in F6Publishing: 465] [Article Influence: 22.6] [Reference Citation Analysis]
468 Pinheiro ML, Feres-Filho EJ, Graves DT, Takiya CM, Elsas MI, Elsas PP, Luz RA. Quantification and localization of platelet-derived growth factor in gingiva of periodontitis patients. J Periodontol 2003;74:323-8. [PMID: 12710751 DOI: 10.1902/jop.2003.74.3.323] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 0.8] [Reference Citation Analysis]
469 Jiang B, Xu S, Brecher P, Cohen RA. Growth factors enhance interleukin-1 beta-induced persistent activation of nuclear factor-kappa B in rat vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2002;22:1811-1816. [PMID: 12426209 DOI: 10.1161/01.atv.0000037679.60584.3f] [Cited by in Crossref: 38] [Cited by in F6Publishing: 16] [Article Influence: 1.9] [Reference Citation Analysis]
470 Mortenson MM, Galante JG, Gilad O, Schlieman MG, Virudachalam S, Kung HJ, Bold RJ. BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer. J Cell Biochem 2007;102:1171-9. [PMID: 17960583 DOI: 10.1002/jcb.21343] [Cited by in Crossref: 34] [Cited by in F6Publishing: 30] [Article Influence: 2.4] [Reference Citation Analysis]
471 Brar SS, Corbin Z, Kennedy TP, Hemendinger R, Thornton L, Bommarius B, Arnold RS, Whorton AR, Sturrock AB, Huecksteadt TP, Quinn MT, Krenitsky K, Ardie KG, Lambeth JD, Hoidal JR. NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. American Journal of Physiology-Cell Physiology 2003;285:C353-69. [DOI: 10.1152/ajpcell.00525.2002] [Cited by in Crossref: 185] [Cited by in F6Publishing: 178] [Article Influence: 9.7] [Reference Citation Analysis]
472 Muranyi AL, Dedhar S, Hogge DE. Combined inhibition of integrin linked kinase and FMS-like tyrosine kinase 3 is cytotoxic to acute myeloid leukemia progenitor cells. Exp Hematol 2009;37:450-60. [PMID: 19302919 DOI: 10.1016/j.exphem.2009.01.002] [Cited by in Crossref: 24] [Cited by in F6Publishing: 25] [Article Influence: 1.8] [Reference Citation Analysis]
473 Chen F, Shi X. Signaling from toxic metals to NF-kappaB and beyond: not just a matter of reactive oxygen species. Environ Health Perspect 2002;110 Suppl 5:807-11. [PMID: 12426136 DOI: 10.1289/ehp.02110s5807] [Cited by in Crossref: 35] [Cited by in F6Publishing: 33] [Article Influence: 1.8] [Reference Citation Analysis]
474 Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015;149:981-92.e11. [PMID: 26055138 DOI: 10.1053/j.gastro.2015.05.057] [Cited by in Crossref: 77] [Cited by in F6Publishing: 81] [Article Influence: 11.0] [Reference Citation Analysis]
475 Rajaram MV, Ganesan LP, Parsa KV, Butchar JP, Gunn JS, Tridandapani S. Akt/Protein kinase B modulates macrophage inflammatory response to Francisella infection and confers a survival advantage in mice. J Immunol 2006;177:6317-24. [PMID: 17056562 DOI: 10.4049/jimmunol.177.9.6317] [Cited by in Crossref: 81] [Cited by in F6Publishing: 85] [Article Influence: 5.1] [Reference Citation Analysis]
476 Whang YE, Yuan XJ, Liu Y, Majumder S, Lewis TD. Regulation of sensitivity to TRAIL by the PTEN tumor suppressor. Vitam Horm. 2004;67:409-426. [PMID: 15110188 DOI: 10.1016/s0083-6729(04)67021-x] [Cited by in Crossref: 29] [Cited by in F6Publishing: 12] [Article Influence: 1.6] [Reference Citation Analysis]
477 Wang Y, Yuan Y, Gao Y, Li X, Tian F, Liu F, Du R, Li P, Wang F, Xu S, Wu X, Wang C. MicroRNA-31 regulating apoptosis by mediating the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in treatment of spinal cord injury. Brain Dev 2019;41:649-61. [PMID: 31036380 DOI: 10.1016/j.braindev.2019.04.010] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 4.0] [Reference Citation Analysis]
478 Koriyama Y, Homma K, Kato S. Activation of Cell Survival Signals in the Goldfish Retinal Ganglion Cells after Optic Nerve Injury. In: Hollyfield JG, Anderson RE, Lavail MM, editors. Retinal Degenerative Diseases. Boston: Springer US; 2006. pp. 333-7. [DOI: 10.1007/0-387-32442-9_47] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Reference Citation Analysis]
479 Chong ZZ, Kang JQ, Maiese K. Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways. Br J Pharmacol 2003;138:1107-18. [PMID: 12684267 DOI: 10.1038/sj.bjp.0705161] [Cited by in Crossref: 125] [Cited by in F6Publishing: 158] [Article Influence: 6.6] [Reference Citation Analysis]
480 Fulda S. Modulation of mitochondrial apoptosis by PI3K inhibitors. Mitochondrion 2013;13:195-8. [PMID: 22580303 DOI: 10.1016/j.mito.2012.05.001] [Cited by in Crossref: 44] [Cited by in F6Publishing: 44] [Article Influence: 4.4] [Reference Citation Analysis]
481 Williams DL, Ozment-Skelton T, Li C. Modulation of the phosphoinositide 3-kinase signaling pathway alters host response to sepsis, inflammation, and ischemia/reperfusion injury. Shock 2006;25:432-9. [PMID: 16680006 DOI: 10.1097/01.shk.0000209542.76305.55] [Cited by in Crossref: 100] [Cited by in F6Publishing: 97] [Article Influence: 6.3] [Reference Citation Analysis]
482 Meacham WD, Antoon JW, Burow ME, Struckhoff AP, Beckman BS. Sphingolipids as determinants of apoptosis and chemoresistance in the MCF-7 cell model system. Exp Biol Med (Maywood) 2009;234:1253-63. [PMID: 19546354 DOI: 10.3181/0902-MR-77] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 1.1] [Reference Citation Analysis]
483 Limpert AS, Carter BD. Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation. J Biol Chem 2010;285:16614-22. [PMID: 20360002 DOI: 10.1074/jbc.M109.098780] [Cited by in Crossref: 22] [Cited by in F6Publishing: 19] [Article Influence: 1.8] [Reference Citation Analysis]
484 Kim SY, Kim JY, Kim SH, Bae HJ, Yi H, Yoon SH, Koo BS, Kwon M, Cho JY, Lee CE, Hong S. Surfactin from Bacillus subtilis displays anti-proliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression. FEBS Lett 2007;581:865-71. [PMID: 17292358 DOI: 10.1016/j.febslet.2007.01.059] [Cited by in Crossref: 114] [Cited by in F6Publishing: 94] [Article Influence: 7.6] [Reference Citation Analysis]
485 Tang Y, Zhou H, Chen A, Pittman RN, Field J. The Akt proto-oncogene links Ras to Pak and cell survival signals. J Biol Chem 2000;275:9106-9. [PMID: 10734042 DOI: 10.1074/jbc.275.13.9106] [Cited by in Crossref: 172] [Cited by in F6Publishing: 163] [Article Influence: 7.8] [Reference Citation Analysis]
486 Xie P, Browning DD, Hay N, Mackman N, Ye RD. Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide 3-kinase and Akt. J Biol Chem 2000;275:24907-14. [PMID: 10801799 DOI: 10.1074/jbc.M001051200] [Cited by in Crossref: 103] [Cited by in F6Publishing: 29] [Article Influence: 4.7] [Reference Citation Analysis]
487 Denlinger CE, Rundall BK, Jones DR. Modulation of antiapoptotic cell signaling pathways in non-small cell lung cancer: the role of NF-κB. Seminars in Thoracic and Cardiovascular Surgery 2004;16:28-39. [DOI: 10.1053/j.semtcvs.2003.12.004] [Cited by in Crossref: 49] [Cited by in F6Publishing: 43] [Article Influence: 2.7] [Reference Citation Analysis]
488 Lee C, Liu S, Chou K, Yeh C, Shiah S, Huang R, Cheng J, Yen C, Shieh Y. Tumor-Associated Macrophages Promote Oral Cancer Progression Through Activation of the Axl Signaling Pathway. Ann Surg Oncol 2014;21:1031-7. [DOI: 10.1245/s10434-013-3400-0] [Cited by in Crossref: 38] [Cited by in F6Publishing: 36] [Article Influence: 4.2] [Reference Citation Analysis]
489 Dhillon NK, Peng F, Ransohoff RM, Buch S. PDGF synergistically enhances IFN-gamma-induced expression of CXCL10 in blood-derived macrophages: implications for HIV dementia. J Immunol 2007;179:2722-30. [PMID: 17709485 DOI: 10.4049/jimmunol.179.5.2722] [Cited by in Crossref: 34] [Cited by in F6Publishing: 35] [Article Influence: 2.3] [Reference Citation Analysis]
490 Jia W, Kong L, Kidoya H, Naito H, Muramatsu F, Hayashi Y, Hsieh HY, Yamakawa D, Hsu DK, Liu FT, Takakura N. Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells. Nat Commun 2021;12:2118. [PMID: 33837181 DOI: 10.1038/s41467-021-22346-2] [Reference Citation Analysis]
491 Matsumoto K, Morisaki T, Kuroki H, Kubo M, Onishi H, Nakamura K, Nakahara C, Kuga H, Baba E, Nakamura M, Hirata K, Tanaka M, Katano M. Exosomes secreted from monocyte-derived dendritic cells support in vitro naive CD4+ T cell survival through NF-κB activation. Cellular Immunology 2004;231:20-9. [DOI: 10.1016/j.cellimm.2004.11.002] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 0.8] [Reference Citation Analysis]
492 Bader AG, Kang S, Zhao L, Vogt PK. Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 2005;5:921-9. [DOI: 10.1038/nrc1753] [Cited by in Crossref: 517] [Cited by in F6Publishing: 496] [Article Influence: 30.4] [Reference Citation Analysis]
493 Yu D, Qin Y, Jun-Qiang L, Shun-Lin G. CNPY2 enhances resistance to apoptosis induced by cisplatin via activation of NF-κB pathway in human non-small cell lung cancer. Biomed Pharmacother 2018;103:1658-63. [PMID: 29864955 DOI: 10.1016/j.biopha.2018.04.123] [Cited by in Crossref: 2] [Article Influence: 0.5] [Reference Citation Analysis]
494 Chau CH, Clavijo CA, Deng HT, Zhang Q, Kim KJ, Qiu Y, Le AD, Ann DK. Etk/Bmx mediates expression of stress-induced adaptive genes VEGF, PAI-1, and iNOS via multiple signaling cascades in different cell systems. Am J Physiol Cell Physiol. 2005;289:C444-C454. [PMID: 15788485 DOI: 10.1152/ajpcell.00410.2004] [Cited by in Crossref: 32] [Cited by in F6Publishing: 30] [Article Influence: 1.9] [Reference Citation Analysis]
495 Khalil H, Loukili N, Regamey A, Cuesta-marban A, Santori E, Huber M, Widmann C. The caspase-3/p120 RasGAP module generates a NF-κB repressor in response to cellular stress. Journal of Cell Science. [DOI: 10.1242/jcs.174409] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.6] [Reference Citation Analysis]
496 Gabriel D, Dvir T, Kohane DS. Delivering bioactive molecules as instructive cues to engineered tissues. Expert Opin Drug Deliv 2012;9:473-92. [PMID: 22432691 DOI: 10.1517/17425247.2012.668521] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 1.1] [Reference Citation Analysis]
497 He Y, Tan X, Hu H, Wang Q, Hu X, Cai X, Guan Y, Chen B, Jing X. Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway. Oncol Lett 2018;15:2939-45. [PMID: 29435022 DOI: 10.3892/ol.2017.7699] [Cited by in Crossref: 2] [Cited by in F6Publishing: 8] [Article Influence: 0.4] [Reference Citation Analysis]
498 Wang H, Zhang Q, Zhang L, Little PJ, Xie X, Meng Q, Ren Y, Zhou L, Gao G, Quirion R, Zheng W. Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells. Neurosci Lett 2012;516:105-9. [PMID: 22490886 DOI: 10.1016/j.neulet.2012.03.068] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 1.9] [Reference Citation Analysis]
499 Taddei ML, Giannoni E, Fiaschi T, Chiarugi P. Anoikis: an emerging hallmark in health and diseases. J Pathol. 2012;226:380-393. [PMID: 21953325 DOI: 10.1002/path.3000] [Cited by in Crossref: 239] [Cited by in F6Publishing: 216] [Article Influence: 23.9] [Reference Citation Analysis]
500 Kodach LL, Bos CL, Durán N, Peppelenbosch MP, Ferreira CV, Hardwick JC. Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells. Carcinogenesis 2006;27:508-16. [PMID: 16344270 DOI: 10.1093/carcin/bgi307] [Cited by in Crossref: 91] [Cited by in F6Publishing: 78] [Article Influence: 5.4] [Reference Citation Analysis]
501 Nidai Ozes O, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. reply: Kinase regulation in inflammatory response. Nature 2000;406:368-368. [DOI: 10.1038/35019157] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.1] [Reference Citation Analysis]
502 Dunn LL, Buckle AM, Cooke JP, Ng MK. The emerging role of the thioredoxin system in angiogenesis. Arterioscler Thromb Vasc Biol 2010;30:2089-98. [PMID: 20798378 DOI: 10.1161/ATVBAHA.110.209643] [Cited by in Crossref: 71] [Cited by in F6Publishing: 43] [Article Influence: 5.9] [Reference Citation Analysis]
503 Lawlor MA, Rotwein P. Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21. Mol Cell Biol 2000;20:8983-95. [PMID: 11073997 DOI: 10.1128/MCB.20.23.8983-8995.2000] [Cited by in Crossref: 147] [Cited by in F6Publishing: 57] [Article Influence: 6.7] [Reference Citation Analysis]
504 Sionov RV, Spokoini R, Kfir-Erenfeld S, Cohen O, Yefenof E. Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis. Adv Cancer Res. 2008;101:127-248. [PMID: 19055945 DOI: 10.1016/s0065-230x(08)00406-5] [Cited by in Crossref: 51] [Cited by in F6Publishing: 35] [Article Influence: 3.9] [Reference Citation Analysis]
505 Cuní S, Pérez-Aciego P, Pérez-Chacón G, Vargas JA, Sánchez A, Martín-Saavedra FM, Ballester S, García-Marco J, Jordá J, Durántez A. A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells. Leukemia 2004;18:1391-400. [PMID: 15175625 DOI: 10.1038/sj.leu.2403398] [Cited by in Crossref: 180] [Cited by in F6Publishing: 176] [Article Influence: 10.0] [Reference Citation Analysis]
506 Jung YJ, Jung JI, Cho HJ, Choi MS, Sung MK, Yu R, Kang YH, Park JH. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci 2014;15:20686-705. [PMID: 25393510 DOI: 10.3390/ijms151120686] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.5] [Reference Citation Analysis]
507 Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, Franklin RA, McCubrey JA. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia. 2003;17:590-603. [PMID: 12646949 DOI: 10.1038/sj.leu.2402824] [Cited by in Crossref: 733] [Cited by in F6Publishing: 708] [Article Influence: 38.6] [Reference Citation Analysis]
508 Facchiano A, De Marchis F, Turchetti E, Facchiano F, Guglielmi M, Denaro A, Palumbo R, Scoccianti M, Capogrossi M. The chemotactic and mitogenic effects of platelet-derived growth factor-BB on rat aorta smooth muscle cells are inhibited by basic fibroblast growth factor. Journal of Cell Science 2000;113:2855-63. [DOI: 10.1242/jcs.113.16.2855] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 0.9] [Reference Citation Analysis]
509 Acharya KD, Veney SL. Characterization of the G-protein-coupled membrane-bound estrogen receptor GPR30 in the zebra finch brain reveals a sex difference in gene and protein expression. Devel Neurobio 2012;72:1433-46. [DOI: 10.1002/dneu.22004] [Cited by in Crossref: 42] [Cited by in F6Publishing: 40] [Article Influence: 4.2] [Reference Citation Analysis]
510 Gong L, Li Y, Nedeljkovic-Kurepa A, Sarkar FH. Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells. Oncogene. 2003;22:4702-4709. [PMID: 12879015 DOI: 10.1038/sj.onc.1206583] [Cited by in Crossref: 154] [Cited by in F6Publishing: 135] [Article Influence: 8.1] [Reference Citation Analysis]
511 Yang K, Arcaroli J, Kupfner J, Pitts TM, Park JS, Strasshiem D, Perng R, Abraham E. Involvement of phosphatidylinositol 3-kinase γ in neutrophil apoptosis. Cellular Signalling 2003;15:225-33. [DOI: 10.1016/s0898-6568(02)00063-3] [Cited by in Crossref: 36] [Cited by in F6Publishing: 16] [Article Influence: 1.9] [Reference Citation Analysis]
512 Jin KL, Mao XO, Nagayama T, Goldsmith PC, Greenberg DA. Induction of vascular endothelial growth factor receptors and phosphatidylinositol 3'-kinase/Akt signaling by global cerebral ischemia in the rat. Neuroscience 2000;100:713-7. [PMID: 11036205 DOI: 10.1016/s0306-4522(00)00331-6] [Cited by in Crossref: 58] [Cited by in F6Publishing: 14] [Article Influence: 2.8] [Reference Citation Analysis]
513 Mohan S, Vander Broek R, Shah S, Eytan DF, Pierce ML, Carlson SG, Coupar JF, Zhang J, Cheng H, Chen Z, Van Waes C. MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma. Clin Cancer Res 2015;21:3946-56. [PMID: 25977343 DOI: 10.1158/1078-0432.CCR-14-3377] [Cited by in Crossref: 46] [Cited by in F6Publishing: 29] [Article Influence: 6.6] [Reference Citation Analysis]
514 Ogawa A, Firth AL, Yao W, Madani MM, Kerr KM, Auger WR, Jamieson SW, Thistlethwaite PA, Yuan JX. Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2009;297:L666-76. [PMID: 19633069 DOI: 10.1152/ajplung.90548.2008] [Cited by in Crossref: 49] [Cited by in F6Publishing: 42] [Article Influence: 3.8] [Reference Citation Analysis]
515 Galbaugh T, Cerrito MG, Jose CC, Cutler ML. EGF-induced activation of Akt results in mTOR-dependent p70S6 kinase phosphorylation and inhibition of HC11 cell lactogenic differentiation. BMC Cell Biol 2006;7:34. [PMID: 16984645 DOI: 10.1186/1471-2121-7-34] [Cited by in Crossref: 49] [Cited by in F6Publishing: 47] [Article Influence: 3.1] [Reference Citation Analysis]
516 Ostman A, Heldin CH. Involvement of platelet-derived growth factor in disease: development of specific antagonists. Adv Cancer Res. 2001;80:1-38. [PMID: 11034538 DOI: 10.1016/s0065-230x(01)80010-5] [Cited by in Crossref: 145] [Cited by in F6Publishing: 39] [Article Influence: 6.9] [Reference Citation Analysis]
517 Paccez JD, Vasques GJ, Correa RG, Vasconcellos JF, Duncan K, Gu X, Bhasin M, Libermann TA, Zerbini LF. The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target. Oncogene 2013;32:689-98. [PMID: 22410775 DOI: 10.1038/onc.2012.89] [Cited by in Crossref: 86] [Cited by in F6Publishing: 70] [Article Influence: 8.6] [Reference Citation Analysis]
518 Pani G, Galeotti T, Chiarugi P. Metastasis: cancer cell's escape from oxidative stress. Cancer Metastasis Rev 2010;29:351-78. [PMID: 20386957 DOI: 10.1007/s10555-010-9225-4] [Cited by in Crossref: 200] [Cited by in F6Publishing: 182] [Article Influence: 16.7] [Reference Citation Analysis]
519 Lu Z, Yu S, Wei J, Wei L. Age-related neural degeneration in nuclear-factor κB p50 knockout mice. Neuroscience 2006;139:965-78. [DOI: 10.1016/j.neuroscience.2005.12.062] [Cited by in Crossref: 32] [Cited by in F6Publishing: 35] [Article Influence: 2.0] [Reference Citation Analysis]
520 Manna SK, Aggarwal BB. Wortmannin inhibits activation of nuclear transcription factors NF-κB and activated protein-1 induced by lipopolysaccharide and phorbol ester. FEBS Letters 2000;473:113-8. [DOI: 10.1016/s0014-5793(00)01501-5] [Cited by in Crossref: 43] [Cited by in F6Publishing: 10] [Article Influence: 2.0] [Reference Citation Analysis]
521 Rajagopalan S, Moyle MW, Joosten I, Long EO. DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells. Sci Signal. 2010;3:ra14. [PMID: 20179272 DOI: 10.1126/scisignal.2000467] [Cited by in Crossref: 40] [Cited by in F6Publishing: 39] [Article Influence: 3.3] [Reference Citation Analysis]
522 Russo MP, Bennett BL, Manning AM, Brenner DA, Jobin C. Differential requirement for NF-κB-inducing kinase in the induction of NF-κB by IL-1β, TNF-α, and Fas. American Journal of Physiology-Cell Physiology 2002;283:C347-57. [DOI: 10.1152/ajpcell.00166.2001] [Cited by in Crossref: 30] [Cited by in F6Publishing: 26] [Article Influence: 1.5] [Reference Citation Analysis]
523 Lilienbaum A, Israël A. From calcium to NF-kappa B signaling pathways in neurons. Mol Cell Biol. 2003;23:2680-2698. [PMID: 12665571 DOI: 10.1128/mcb.23.8.2680-2698.2003] [Cited by in Crossref: 161] [Cited by in F6Publishing: 64] [Article Influence: 8.5] [Reference Citation Analysis]
524 Kim AH, Khursigara G, Sun X, Franke TF, Chao MV. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 2001;21:893-901. [PMID: 11154276 DOI: 10.1128/MCB.21.3.893-901.2001] [Cited by in Crossref: 507] [Cited by in F6Publishing: 216] [Article Influence: 24.1] [Reference Citation Analysis]
525 von Gise A, Lorenz P, Wellbrock C, Hemmings B, Berberich-Siebelt F, Rapp UR, Troppmair J. Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals. Mol Cell Biol 2001;21:2324-36. [PMID: 11259582 DOI: 10.1128/MCB.21.7.2324-2336.2001] [Cited by in Crossref: 120] [Cited by in F6Publishing: 23] [Article Influence: 5.7] [Reference Citation Analysis]
526 Tang CH, Lu DY, Yang RS, Tsai HY, Kao MC, Fu WM, Chen YF. Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. J Immunol 2007;179:1292-302. [PMID: 17617622 DOI: 10.4049/jimmunol.179.2.1292] [Cited by in Crossref: 110] [Cited by in F6Publishing: 110] [Article Influence: 7.3] [Reference Citation Analysis]
527 Thakkar H, Chen X, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK. Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance. J Biol Chem. 2001;276:38361-38369. [PMID: 11461904 DOI: 10.1074/jbc.m103321200] [Cited by in Crossref: 80] [Cited by in F6Publishing: 17] [Article Influence: 3.8] [Reference Citation Analysis]
528 Samuel SM, Akita Y, Paul D, Thirunavukkarasu M, Zhan L, Sudhakaran PR, Li C, Maulik N. Coadministration of adenoviral vascular endothelial growth factor and angiopoietin-1 enhances vascularization and reduces ventricular remodeling in the infarcted myocardium of type 1 diabetic rats. Diabetes 2010;59:51-60. [PMID: 19794062 DOI: 10.2337/db09-0336] [Cited by in Crossref: 45] [Cited by in F6Publishing: 44] [Article Influence: 3.5] [Reference Citation Analysis]
529 Banerjee S, Li Y, Wang Z, Sarkar FH. Multi-targeted therapy of cancer by genistein. Cancer Lett. 2008;269:226-242. [PMID: 18492603 DOI: 10.1016/j.canlet.2008.03.052] [Cited by in Crossref: 375] [Cited by in F6Publishing: 321] [Article Influence: 26.8] [Reference Citation Analysis]
530 Meng F, D'Mello SR. NF-kappaB stimulates Akt phosphorylation and gene expression by distinct signaling mechanisms. Biochim Biophys Acta. 2003;1630:35-40. [PMID: 14580677 DOI: 10.1016/j.bbaexp.2003.09.001] [Cited by in Crossref: 21] [Cited by in F6Publishing: 25] [Article Influence: 1.1] [Reference Citation Analysis]
531 Monick MM, Carter AB, Robeff PK, Flaherty DM, Peterson MW, Hunninghake GW. Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin. J Immunol 2001;166:4713-20. [PMID: 11254732 DOI: 10.4049/jimmunol.166.7.4713] [Cited by in Crossref: 135] [Cited by in F6Publishing: 134] [Article Influence: 6.4] [Reference Citation Analysis]
532 Goyal A, Wang Y, Graham MM, Doseff AI, Bhatt NY, Marsh CB. Monocyte survival factors induce Akt activation and suppress caspase-3. Am J Respir Cell Mol Biol 2002;26:224-30. [PMID: 11804874 DOI: 10.1165/ajrcmb.26.2.4640] [Cited by in Crossref: 59] [Cited by in F6Publishing: 61] [Article Influence: 3.0] [Reference Citation Analysis]
533 Wang L, Phan DD, Zhang J, Ong PS, Thuya WL, Soo R, Wong AL, Yong WP, Lee SC, Ho PC, Sethi G, Goh BC. Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development. Oncotarget 2016;7:44790-802. [PMID: 27027349 DOI: 10.18632/oncotarget.8316] [Cited by in Crossref: 28] [Cited by in F6Publishing: 27] [Article Influence: 7.0] [Reference Citation Analysis]
534 Bai J, Wang Y, Zhu X, Shi J. Eriodictyol inhibits high glucose-induced extracellular matrix accumulation, oxidative stress, and inflammation in human glomerular mesangial cells. Phytother Res 2019;33:2775-82. [PMID: 31373419 DOI: 10.1002/ptr.6463] [Cited by in Crossref: 14] [Cited by in F6Publishing: 14] [Article Influence: 4.7] [Reference Citation Analysis]
535 Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K. Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase. J Biol Chem 2015;290:16043-58. [PMID: 25940087 DOI: 10.1074/jbc.M114.635755] [Cited by in Crossref: 43] [Cited by in F6Publishing: 21] [Article Influence: 6.1] [Reference Citation Analysis]
536 Dai DL, Martinka M, Li G. Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases. J Clin Oncol. 2005;23:1473-1482. [PMID: 15735123 DOI: 10.1200/jco.2005.07.168] [Cited by in Crossref: 199] [Cited by in F6Publishing: 100] [Article Influence: 11.7] [Reference Citation Analysis]
537 Kirito K, Watanabe T, Sawada K, Endo H, Ozawa K, Komatsu N. Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways. J Biol Chem 2002;277:8329-37. [PMID: 11756417 DOI: 10.1074/jbc.M109824200] [Cited by in Crossref: 67] [Cited by in F6Publishing: 31] [Article Influence: 3.2] [Reference Citation Analysis]
538 Aldinucci D, Olivo K, Lorenzon D, Poletto D, Gloghini A, Carbone A, Pinto A. The role of interleukin-3 in classical Hodgkin's disease. Leuk Lymphoma 2005;46:303-11. [PMID: 15621820 DOI: 10.1080/10428190400013712] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 1.4] [Reference Citation Analysis]
539 Jin S, Pang R, Shen J, Huang G, Wang J, Zhou J. Grifolin induces apoptosis via inhibition of PI3K/AKT signalling pathway in human osteosarcoma cells. Apoptosis 2007;12:1317-26. [DOI: 10.1007/s10495-007-0062-z] [Cited by in Crossref: 53] [Cited by in F6Publishing: 44] [Article Influence: 3.5] [Reference Citation Analysis]
540 Matsuda N, Horikawa M, Watanabe M, Kitagawa S, Kudo Y, Takata T. Possible involvement of extracellular signal-regulated kinases 1/2 in mitogenic response of periodontal ligament cells to enamel matrix derivative. European Journal of Oral Sciences 2002;110:439-44. [DOI: 10.1034/j.1600-0722.2002.21340.x] [Cited by in Crossref: 29] [Cited by in F6Publishing: 25] [Article Influence: 1.5] [Reference Citation Analysis]
541 Chandrasekar B, Bysani S, Mummidi S. CXCL16 signals via Gi, phosphatidylinositol 3-kinase, Akt, I kappa B kinase, and nuclear factor-kappa B and induces cell-cell adhesion and aortic smooth muscle cell proliferation. J Biol Chem 2004;279:3188-96. [PMID: 14625285 DOI: 10.1074/jbc.M311660200] [Cited by in Crossref: 111] [Cited by in F6Publishing: 41] [Article Influence: 5.8] [Reference Citation Analysis]
542 LoPiccolo J, Granville CA, Gills JJ, Dennis PA. Targeting Akt in cancer therapy. Anticancer Drugs 2007;18:861-74. [PMID: 17667591 DOI: 10.1097/CAD.0b013e3280cc2c6f] [Cited by in Crossref: 17] [Cited by in F6Publishing: 51] [Article Influence: 1.1] [Reference Citation Analysis]
543 Pan Y, Liu D, Wei Y, Su D, Lu C, Hu Y, Zhou F. Azelaic Acid Exerts Antileukemic Activity in Acute Myeloid Leukemia. Front Pharmacol 2017;8:359. [PMID: 28659796 DOI: 10.3389/fphar.2017.00359] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 2.6] [Reference Citation Analysis]
544 Wang Y, Chang J, Li Y, Li Y, Shyy JY, Chien S. Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway. American Journal of Physiology-Heart and Circulatory Physiology 2004;286:H685-92. [DOI: 10.1152/ajpheart.00237.2003] [Cited by in Crossref: 49] [Cited by in F6Publishing: 41] [Article Influence: 2.7] [Reference Citation Analysis]
545 Tanaka H, Fujita N, Tsuruo T. 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling. J Biol Chem. 2005;280:40965-40973. [PMID: 16207722 DOI: 10.1074/jbc.m506235200] [Cited by in Crossref: 68] [Cited by in F6Publishing: 28] [Article Influence: 4.0] [Reference Citation Analysis]
546 Bui NT, König HG, Culmsee C, Bauerbach E, Poppe M, Krieglstein J, Prehn JH. p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones. J Neurochem 2002;81:594-605. [PMID: 12065668 DOI: 10.1046/j.1471-4159.2002.00841.x] [Cited by in Crossref: 50] [Cited by in F6Publishing: 55] [Article Influence: 2.5] [Reference Citation Analysis]
547 Machida H, Matsumoto Y, Shirai M, Kubota N. Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation. International Journal of Radiation Biology 2009;79:973-80. [DOI: 10.1080/09553000310001626135] [Cited by in Crossref: 63] [Cited by in F6Publishing: 50] [Article Influence: 4.8] [Reference Citation Analysis]
548 Parikh A, Stephan AF, Tzanakakis ES. Regenerating proteins and their expression, regulation and signaling. Biomol Concepts. 2012;3:57-70. [PMID: 22582090 DOI: 10.1515/bmc.2011.055] [Cited by in Crossref: 64] [Cited by in F6Publishing: 58] [Article Influence: 5.8] [Reference Citation Analysis]
549 Dogra C, Changotra H, Wergedal JE, Kumar A. Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch. J Cell Physiol 2006;208:575-85. [DOI: 10.1002/jcp.20696] [Cited by in Crossref: 73] [Cited by in F6Publishing: 70] [Article Influence: 4.6] [Reference Citation Analysis]
550 Müller M, Morotti A, Ponzetto C. Activation of NF-kappaB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis. Mol Cell Biol 2002;22:1060-72. [PMID: 11809798 DOI: 10.1128/MCB.22.4.1060-1072.2002] [Cited by in Crossref: 90] [Cited by in F6Publishing: 38] [Article Influence: 4.5] [Reference Citation Analysis]
551 Rahmani M, Yu C, Reese E, Ahmed W, Hirsch K, Dent P, Grant S. Inhibition of PI-3 kinase sensitizes human leukemic cells to histone deacetylase inhibitor-mediated apoptosis through p44/42 MAP kinase inactivation and abrogation of p21CIP1/WAF1 induction rather than AKT inhibition. Oncogene 2003;22:6231-42. [DOI: 10.1038/sj.onc.1206646] [Cited by in Crossref: 75] [Cited by in F6Publishing: 65] [Article Influence: 3.9] [Reference Citation Analysis]
552 Choi J, Kim J, Kim D, Chun M, Gwag BJ, Yoon SK, Joo C. Failure to activate NF-κB promotes apoptosis of retinal ganglion cells following optic nerve transection. Brain Research 2000;883:60-8. [DOI: 10.1016/s0006-8993(00)02886-9] [Cited by in Crossref: 33] [Cited by in F6Publishing: 7] [Article Influence: 1.5] [Reference Citation Analysis]
553 Amaya MJ, Goulart VAM, Santos AK, Kihara AH, Guatimosim S, Resende RR. Role of Calcium Signaling in Stem and Cancer Cell Proliferation. In: Resende RR, Ulrich H, editors. Trends in Stem Cell Proliferation and Cancer Research. Dordrecht: Springer Netherlands; 2013. pp. 93-137. [DOI: 10.1007/978-94-007-6211-4_5] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
554 Vengoji R, Macha MA, Batra SK, Shonka NA. Natural products: a hope for glioblastoma patients. Oncotarget 2018;9:22194-219. [PMID: 29774132 DOI: 10.18632/oncotarget.25175] [Cited by in Crossref: 41] [Cited by in F6Publishing: 39] [Article Influence: 10.3] [Reference Citation Analysis]
555 Varticovski L, Lu Z, Mitchell K, de Aos I, Kopeček J. Water-soluble HPMA copolymer–wortmannin conjugate retains phosphoinositide 3-kinase inhibitory activity in vitro and in vivo. Journal of Controlled Release 2001;74:275-81. [DOI: 10.1016/s0168-3659(01)00349-2] [Cited by in Crossref: 20] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
556 Gupta A. Leptin as a neuroprotective agent in glaucoma. Med Hypotheses 2013;81:797-802. [PMID: 24035688 DOI: 10.1016/j.mehy.2013.08.023] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
557 Linton MF, Babaev VR, Huang J, Linton EF, Tao H, Yancey PG. Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis. Circ J 2016;80:2259-68. [PMID: 27725526 DOI: 10.1253/circj.CJ-16-0924] [Cited by in Crossref: 76] [Cited by in F6Publishing: 51] [Article Influence: 12.7] [Reference Citation Analysis]
558 Li X, Zhu M, Brasier AR, Kudlicki AS. Inferring genome-wide functional modulatory network: a case study on NF-κB/RelA transcription factor. J Comput Biol 2015;22:300-12. [PMID: 25844669 DOI: 10.1089/cmb.2014.0299] [Cited by in Crossref: 17] [Cited by in F6Publishing: 14] [Article Influence: 2.8] [Reference Citation Analysis]
559 Bierne H, Cossart P. InlB, a surface protein of Listeria monocytogenes that behaves as an invasin and a growth factor. Journal of Cell Science 2002;115:3357-67. [DOI: 10.1242/jcs.115.17.3357] [Cited by in Crossref: 47] [Cited by in F6Publishing: 27] [Article Influence: 2.4] [Reference Citation Analysis]
560 Brywe KG, Leverin AL, Gustavsson M, Mallard C, Granata R, Destefanis S, Volante M, Hagberg H, Ghigo E, Isgaard J. Growth hormone-releasing peptide hexarelin reduces neonatal brain injury and alters Akt/glycogen synthase kinase-3beta phosphorylation. Endocrinology 2005;146:4665-72. [PMID: 16081643 DOI: 10.1210/en.2005-0389] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 1.4] [Reference Citation Analysis]
561 Cho D, Mier JW, Atkins MB. PI3K/Akt/mTOR Pathway: A Growth and Proliferation Pathway. In: Bukowski RM, Figlin RA, Motzer RJ, editors. Renal Cell Carcinoma. Totowa: Humana Press; 2009. pp. 267-85. [DOI: 10.1007/978-1-59745-332-5_15] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.4] [Reference Citation Analysis]
562 Lee JH, Jung HS, Giang PM, Jin X, Lee S, Son PT, Lee D, Hong YS, Lee K, Lee JJ. Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera. J Pharmacol Exp Ther 2006;316:271-8. [PMID: 16183703 DOI: 10.1124/jpet.105.092486] [Cited by in Crossref: 84] [Cited by in F6Publishing: 79] [Article Influence: 4.9] [Reference Citation Analysis]
563 Howe CJ, Lahair MM, Maxwell JA, Lee JT, Robinson PJ, Rodriguez-mora O, Mccubrey JA, Franklin RA. Participation of the Calcium/Calmodulin-dependent Kinases in Hydrogen Peroxide-induced IκB Phosphorylation in Human T Lymphocytes. Journal of Biological Chemistry 2002;277:30469-76. [DOI: 10.1074/jbc.m205036200] [Cited by in Crossref: 47] [Cited by in F6Publishing: 16] [Article Influence: 2.4] [Reference Citation Analysis]
564 Strozyk E, Kulms D. The role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescence. Int J Mol Sci. 2013;14:15260-15285. [PMID: 23887651 DOI: 10.3390/ijms140815260] [Cited by in Crossref: 86] [Cited by in F6Publishing: 80] [Article Influence: 9.6] [Reference Citation Analysis]
565 Sarkar A, Hellberg L, Bhattacharyya A, Behnen M, Wang K, Lord JM, Möller S, Kohler M, Solbach W, Laskay T. Infection with Anaplasma phagocytophilum activates the phosphatidylinositol 3-Kinase/Akt and NF-κB survival pathways in neutrophil granulocytes. Infect Immun 2012;80:1615-23. [PMID: 22252875 DOI: 10.1128/IAI.05219-11] [Cited by in Crossref: 28] [Cited by in F6Publishing: 18] [Article Influence: 2.8] [Reference Citation Analysis]
566 Cuesta C, Arévalo-Alameda C, Castellano E. The Importance of Being PI3K in the RAS Signaling Network. Genes (Basel) 2021;12:1094. [PMID: 34356110 DOI: 10.3390/genes12071094] [Reference Citation Analysis]
567 Giannoni E, Parri M, Chiarugi P. EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy. Antioxid Redox Signal. 2012;16:1248-1263. [PMID: 21929373 DOI: 10.1089/ars.2011.4280] [Cited by in Crossref: 117] [Cited by in F6Publishing: 118] [Article Influence: 10.6] [Reference Citation Analysis]
568 Lorenz W, Buhrmann C, Mobasheri A, Lueders C, Shakibaei M. Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis. Arthritis Res Ther 2013;15:R111. [PMID: 24020912 DOI: 10.1186/ar4291] [Cited by in Crossref: 42] [Cited by in F6Publishing: 40] [Article Influence: 5.3] [Reference Citation Analysis]
569 Meucci O, Fatatis A, Simen AA, Miller RJ. Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival. Proc Natl Acad Sci U S A 2000;97:8075-80. [PMID: 10869418 DOI: 10.1073/pnas.090017497] [Cited by in Crossref: 260] [Cited by in F6Publishing: 263] [Article Influence: 11.8] [Reference Citation Analysis]
570 Chojnacka K, Lewandowska U. The Antiangiogenic Activity of Polyphenol-Rich Extracts and Its Implication on Cancer Chemoprevention. Food Reviews International 2020;36:77-103. [DOI: 10.1080/87559129.2019.1630634] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 1.3] [Reference Citation Analysis]
571 Spiegelman VS, Slaga TJ, Pagano M, Minamoto T, Ronai Z, Fuchs SY. Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Mol Cell 2000;5:877-82. [PMID: 10882123 DOI: 10.1016/s1097-2765(00)80327-5] [Cited by in Crossref: 114] [Cited by in F6Publishing: 61] [Article Influence: 5.2] [Reference Citation Analysis]
572 Smyth LCD, Highet B, Jansson D, Wu J, Rustenhoven J, Aalderink M, Tan A, Li S, Johnson R, Coppieters N, Handley R, Narayan P, Singh-Bains MK, Schweder P, Turner C, Mee EW, Heppner P, Correia J, Park TI, Curtis MA, Faull RLM, Dragunow M. Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer's disease. Commun Biol 2022;5:235. [PMID: 35301433 DOI: 10.1038/s42003-022-03180-8] [Reference Citation Analysis]
573 LoPiccolo J, Blumenthal GM, Bernstein WB, Dennis PA. Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations. Drug Resist Updat. 2009;11:32-50. [PMID: 18166498 DOI: 10.1016/j.drup.2007.11.003] [Cited by in Crossref: 515] [Cited by in F6Publishing: 497] [Article Influence: 34.3] [Reference Citation Analysis]
574 Meeran SM, Katiyar N, Singh T, Katiyar SK. Loss of endogenous interleukin-12 activates survival signals in ultraviolet-exposed mouse skin and skin tumors. Neoplasia 2009;11:846-55. [PMID: 19724678 DOI: 10.1593/neo.09528] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 1.0] [Reference Citation Analysis]
575 Zhang X, Chen T, Zhang J, Mao Q, Li S, Xiong W, Qiu Y, Xie Q, Ge J. Notch1 promotes glioma cell migration and invasion by stimulating β-catenin and NF-κB signaling via AKT activation. Cancer Sci 2012;103:181-90. [PMID: 22093097 DOI: 10.1111/j.1349-7006.2011.02154.x] [Cited by in Crossref: 88] [Cited by in F6Publishing: 82] [Article Influence: 8.0] [Reference Citation Analysis]
576 Roy P, Sarkar UA, Basak S. The NF-κB Activating Pathways in Multiple Myeloma. Biomedicines 2018;6:E59. [PMID: 29772694 DOI: 10.3390/biomedicines6020059] [Cited by in Crossref: 28] [Cited by in F6Publishing: 22] [Article Influence: 7.0] [Reference Citation Analysis]
577 Bonacchi A, Romagnani P, Romanelli RG, Efsen E, Annunziato F, Lasagni L, Francalanci M, Serio M, Laffi G, Pinzani M. Signal transduction by the chemokine receptor CXCR3: activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes. J Biol Chem. 2001;276:9945-9954. [PMID: 11136732 DOI: 10.1074/jbc.M010303200] [Cited by in Crossref: 224] [Cited by in F6Publishing: 83] [Article Influence: 10.7] [Reference Citation Analysis]
578 Jin Q, Wei G, Lin Z, Sugai JV, Lynch SE, Ma PX, Giannobile WV. Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo. PLoS One 2008;3:e1729. [PMID: 18320048 DOI: 10.1371/journal.pone.0001729] [Cited by in Crossref: 64] [Cited by in F6Publishing: 53] [Article Influence: 4.6] [Reference Citation Analysis]
579 Yadav V, Varum F, Bravo R, Furrer E, Bojic D, Basit AW. Inflammatory bowel disease: exploring gut pathophysiology for novel therapeutic targets. Transl Res 2016;176:38-68. [PMID: 27220087 DOI: 10.1016/j.trsl.2016.04.009] [Cited by in Crossref: 85] [Cited by in F6Publishing: 81] [Article Influence: 14.2] [Reference Citation Analysis]
580 Di Iorio P, Ballerini P, Traversa U, Nicoletti F, D'alimonte I, Kleywegt S, Werstiuk ES, Rathbone MP, Caciagli F, Ciccarelli R. The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. Glia 2004;46:356-68. [DOI: 10.1002/glia.20002] [Cited by in Crossref: 57] [Cited by in F6Publishing: 54] [Article Influence: 3.2] [Reference Citation Analysis]
581 Purcell NH, Yu C, He D, Xiang J, Paran N, DiDonato JA, Yamaoka S, Shaul Y, Lin A. Activation of NF-kappaB by hepatitis B virus X protein through an IkappaB kinase-independent mechanism. Am J Physiol Gastrointest Liver Physiol 2001;280:G669-77. [PMID: 11254493 DOI: 10.1152/ajpgi.2001.280.4.G669] [Cited by in Crossref: 13] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
582 Ito A, Saito H, Mitobe K, Minamiya Y, Takahashi N, Maruyama K, Motoyama S, Katayose Y, Ogawa J. Inhibition of heat shock protein 90 sensitizes melanoma cells to thermosensitive ferromagnetic particle-mediated hyperthermia with low Curie temperature. Cancer Science 2009;100:558-64. [DOI: 10.1111/j.1349-7006.2008.01072.x] [Cited by in Crossref: 38] [Cited by in F6Publishing: 22] [Article Influence: 2.9] [Reference Citation Analysis]
583 Biswas DK, Cruz AP, Gansberger E, Pardee AB. Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci U S A 2000;97:8542-7. [PMID: 10900013 DOI: 10.1073/pnas.97.15.8542] [Cited by in Crossref: 243] [Cited by in F6Publishing: 220] [Article Influence: 11.0] [Reference Citation Analysis]
584 Bruhn MA, Pearson RB, Hannan RD, Sheppard KE. AKT-independent PI3-K signaling in cancer - emerging role for SGK3. Cancer Manag Res 2013;5:281-92. [PMID: 24009430 DOI: 10.2147/CMAR.S35178] [Cited by in Crossref: 4] [Cited by in F6Publishing: 39] [Article Influence: 0.4] [Reference Citation Analysis]
585 Dong B, Valencia CA, Liu R. Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1. J Biol Chem. 2007;282:25131-25140. [PMID: 17580302 DOI: 10.1074/jbc.M702123200] [Cited by in Crossref: 32] [Cited by in F6Publishing: 20] [Article Influence: 2.1] [Reference Citation Analysis]
586 Wang S, Zhang L, Ma Y, Chen L, Tian Y, Mao J, Martyn JJ. Nociceptive behavior following hindpaw burn injury in young rats: response to systemic morphine. Pain Med 2011;12:87-98. [PMID: 21143761 DOI: 10.1111/j.1526-4637.2010.01021.x] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 1.4] [Reference Citation Analysis]
587 Costoya JA, Ríos R, García-Barros M, Gallego R, García-Caballero T, Señarís R, Arce VM, Devesa J. Role of growth hormone receptor in HL-60 cell survival. Mol Cell Biol Res Commun 2000;4:26-31. [PMID: 11152624 DOI: 10.1006/mcbr.2000.0252] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.1] [Reference Citation Analysis]
588 Pap M, Cooper GM. Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway. Mol Cell Biol 2002;22:578-86. [PMID: 11756553 DOI: 10.1128/MCB.22.2.578-586.2002] [Cited by in Crossref: 118] [Cited by in F6Publishing: 40] [Article Influence: 5.9] [Reference Citation Analysis]
589 Kim M, Lu F, Zhang Y. Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer. Cell Rep 2016;17:275-88. [PMID: 27681437 DOI: 10.1016/j.celrep.2016.09.003] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 4.6] [Reference Citation Analysis]
590 Wyatt GL, Crump LS, Young CM, Wessells VM, McQueen CM, Wall SW, Gustafson TL, Fan YY, Chapkin RS, Porter WW, Lyons TR. Cross-talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer. Breast Cancer Res 2019;21:131. [PMID: 31783895 DOI: 10.1186/s13058-019-1224-y] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
591 Sarkar FH, Li Y. Soy isoflavones and cancer prevention. Cancer Invest. 2003;21:744-757. [PMID: 14628433 DOI: 10.1081/cnv-120023773] [Cited by in Crossref: 252] [Cited by in F6Publishing: 70] [Article Influence: 13.3] [Reference Citation Analysis]
592 Yamazaki K, Yamazaki T, Taki S, Miyake K, Hayashi T, Ochs HD, Agematsu K. Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling. Clinical Immunology 2010;135:125-36. [DOI: 10.1016/j.clim.2009.12.013] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 1.3] [Reference Citation Analysis]
593 Zheng WH, Quirion R. Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells. BMC Neurosci 2006;7:51. [PMID: 16792806 DOI: 10.1186/1471-2202-7-51] [Cited by in Crossref: 62] [Cited by in F6Publishing: 59] [Article Influence: 3.9] [Reference Citation Analysis]
594 Chuenkova MV, PereiraPerrin M. Trypanosoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategy. Sci Signal 2009;2:ra74. [PMID: 19920252 DOI: 10.1126/scisignal.2000374] [Cited by in Crossref: 42] [Cited by in F6Publishing: 39] [Article Influence: 3.2] [Reference Citation Analysis]
595 Massaeli H, Jalali S, Viswanathan D, Mesaeli N. Loss of calreticulin function decreases NFκB activity by stabilizing IκB protein. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2014;1843:2385-93. [DOI: 10.1016/j.bbamcr.2014.06.017] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.4] [Reference Citation Analysis]
596 Castellano E, Downward J. RAS Interaction with PI3K: More Than Just Another Effector Pathway. Genes Cancer 2011;2:261-74. [PMID: 21779497 DOI: 10.1177/1947601911408079] [Cited by in Crossref: 412] [Cited by in F6Publishing: 398] [Article Influence: 37.5] [Reference Citation Analysis]
597 Hua KT, Way TD, Lin JK. Pentagalloylglucose inhibits estrogen receptor alpha by lysosome-dependent depletion and modulates ErbB/PI3K/Akt pathway in human breast cancer MCF-7 cells. Mol Carcinog 2006;45:551-60. [PMID: 16637063 DOI: 10.1002/mc.20226] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 1.4] [Reference Citation Analysis]
598 Koul D, Takada Y, Shen R, Aggarwal BB, Yung WK. PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappaB signaling pathway in human glioma cells. Biochem Biophys Res Commun 2006;350:463-71. [PMID: 17011514 DOI: 10.1016/j.bbrc.2006.09.077] [Cited by in Crossref: 24] [Cited by in F6Publishing: 29] [Article Influence: 1.5] [Reference Citation Analysis]
599 Dhillon N, Zhu X, Peng F, Yao H, Williams R, Qiu J, Callen S, Ladner AO, Buch S. Molecular mechanism(s) involved in the synergistic induction of CXCL10 by human immunodeficiency virus type 1 Tat and interferon-gamma in macrophages. J Neurovirol 2008;14:196-204. [PMID: 18569454 DOI: 10.1080/13550280801993648] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.0] [Reference Citation Analysis]
600 Marchisio M, Brugnoli F, Santavenere E, Paludi M, Ciccocioppo F, Miscia S. Mitigation of tumor necrosis factor alpha cytotoxicity by aurintricarboxylic acid in human peripheral B lymphocytes. Biochem Pharmacol 2003;66:1973-9. [PMID: 14599555 DOI: 10.1016/s0006-2952(03)00583-5] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
601 Saxena U, Timmer RT, Pillarisetti S. New approaches for treatment of diabetic nephropathy: the endothelium as a target for drug discovery. Expert Opin Ther Targets 2001;5:539-45. [PMID: 12540281 DOI: 10.1517/14728222.5.5.539] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.1] [Reference Citation Analysis]
602 Sun S, Steinberg BM. PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells. J Gen Virol 2002;83:1651-8. [PMID: 12075083 DOI: 10.1099/0022-1317-83-7-1651] [Cited by in Crossref: 82] [Cited by in F6Publishing: 72] [Article Influence: 4.1] [Reference Citation Analysis]
603 Grammer AC, Lipsky PE. CD40-mediated regulation of immune responses by TRAF-dependent and TRAF-independent signaling mechanisms. Adv Immunol 2000;76:61-178. [PMID: 11079098 DOI: 10.1016/s0065-2776(01)76019-1] [Cited by in Crossref: 64] [Cited by in F6Publishing: 22] [Article Influence: 3.0] [Reference Citation Analysis]
604 Hill R, Kalathur RK, Callejas S, Colaço L, Brandão R, Serelde B, Cebriá A, Blanco-Aparicio C, Pastor J, Futschik M, Dopazo A, Link W. A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes. Breast Cancer Res 2014;16:482. [PMID: 25488803 DOI: 10.1186/s13058-014-0482-y] [Cited by in Crossref: 22] [Cited by in F6Publishing: 20] [Article Influence: 2.8] [Reference Citation Analysis]
605 Thompson JE, Thompson CB. Putting the rap on Akt. J Clin Oncol 2004;22:4217-26. [PMID: 15483033 DOI: 10.1200/JCO.2004.01.103] [Cited by in Crossref: 161] [Cited by in F6Publishing: 44] [Article Influence: 8.9] [Reference Citation Analysis]
606 Toth A, Halmosi R, Kovacs K, Deres P, Kalai T, Hideg K, Toth K, Sumegi B. Akt activation induced by an antioxidant compound during ischemia-reperfusion. Free Radical Biology and Medicine 2003;35:1051-63. [DOI: 10.1016/s0891-5849(03)00467-2] [Cited by in Crossref: 36] [Cited by in F6Publishing: 13] [Article Influence: 1.9] [Reference Citation Analysis]
607 Sragovich S, Bromberg Y, Sperling O, Zoref-shani E. Molecular Alterations Associated with the NMDA Preconditioning-Induced Neuroprotective Mechanism Against Glutamate Cytotoxicity. J Mol Neurosci 2012;47:519-32. [DOI: 10.1007/s12031-011-9668-2] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
608 Krainock R, Murphy S. Heregulin upregulates the expression of nitric oxide synthase (NOS)-1 in rat cerebellar granule neurons via the ErbB4 receptor: NOS-1 regulation by heregulin. Journal of Neurochemistry 2001;76:312-5. [DOI: 10.1046/j.1471-4159.2001.00089.x] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
609 Reif S, Lang A, Lindquist JN, Yata Y, Gabele E, Scanga A, Brenner DA, Rippe RA. The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. J Biol Chem. 2003;278:8083-8090. [PMID: 12502711 DOI: 10.1074/jbc.m212927200] [Cited by in Crossref: 209] [Cited by in F6Publishing: 89] [Article Influence: 10.5] [Reference Citation Analysis]
610 Calautti E, Li J, Saoncella S, Brissette JL, Goetinck PF. Phosphoinositide 3-Kinase Signaling to Akt Promotes Keratinocyte Differentiation Versus Death. Journal of Biological Chemistry 2005;280:32856-65. [DOI: 10.1074/jbc.m506119200] [Cited by in Crossref: 153] [Cited by in F6Publishing: 69] [Article Influence: 9.0] [Reference Citation Analysis]
611 Kim DJ, Lee MH, Liu K, Lim DY, Roh E, Chen H, Kim SH, Shim JH, Kim MO, Li W, Ma F, Fredimoses M, Bode AM, Dong Z. Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC. Carcinogenesis 2017;38:1136-46. [PMID: 29029040 DOI: 10.1093/carcin/bgx082] [Cited by in Crossref: 17] [Cited by in F6Publishing: 15] [Article Influence: 3.4] [Reference Citation Analysis]
612 Fisslthaler B, Benzing T, Busse R, Fleming I. Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. Nitric Oxide 2003;8:253-61. [DOI: 10.1016/s1089-8603(03)00042-9] [Cited by in Crossref: 59] [Cited by in F6Publishing: 21] [Article Influence: 3.1] [Reference Citation Analysis]
613 Kawagoe J, Ohmichi M, Takahashi T, Ohshima C, Mabuchi S, Takahashi K, Igarashi H, Mori-abe A, Saitoh M, Du B, Ohta T, Kimura A, Kyo S, Inoue M, Kurachi H. Raloxifene Inhibits Estrogen-induced Up-regulation of Telomerase Activity in a Human Breast Cancer Cell Line. Journal of Biological Chemistry 2003;278:43363-72. [DOI: 10.1074/jbc.m304363200] [Cited by in Crossref: 49] [Cited by in F6Publishing: 14] [Article Influence: 2.6] [Reference Citation Analysis]
614 Yoganathan T, Costello P, Chen X, Jabali M, Yan J, Leung D, Zhang Z, Yee A, Dedhar S, Sanghera J. Integrin-linked kinase (ILK): a “hot” therapeutic target. Biochemical Pharmacology 2000;60:1115-9. [DOI: 10.1016/s0006-2952(00)00444-5] [Cited by in Crossref: 64] [Cited by in F6Publishing: 22] [Article Influence: 2.9] [Reference Citation Analysis]
615 Anusaksathien O, Jin Q, Zhao M, Somerman MJ, Giannobile WV. Effect of sustained gene delivery of platelet-derived growth factor or its antagonist (PDGF-1308) on tissue-engineered cementum. J Periodontol 2004;75:429-40. [PMID: 15088882 DOI: 10.1902/jop.2004.75.3.429] [Cited by in Crossref: 46] [Cited by in F6Publishing: 39] [Article Influence: 2.6] [Reference Citation Analysis]
616 Hirsch E, Ciraolo E, Ghigo A, Costa C. Taming the PI3K team to hold inflammation and cancer at bay. Pharmacol Ther. 2008;118:192-205. [PMID: 18420279 DOI: 10.1016/j.pharmthera.2008.02.004] [Cited by in Crossref: 52] [Cited by in F6Publishing: 53] [Article Influence: 3.7] [Reference Citation Analysis]
617 Bistrović A, Grbčić P, Harej A, Sedić M, Kraljević-Pavelić S, Koštrun S, Plavec J, Makuc D, Raić-Malić S. Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549. J Enzyme Inhib Med Chem 2018;33:271-85. [PMID: 29271659 DOI: 10.1080/14756366.2017.1414807] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 2.0] [Reference Citation Analysis]
618 Vanhaesebroeck B, Waterfield MD. Signaling by distinct classes of phosphoinositide 3-kinases. Exp Cell Res 1999;253:239-54. [PMID: 10579926 DOI: 10.1006/excr.1999.4701] [Cited by in Crossref: 617] [Cited by in F6Publishing: 598] [Article Influence: 26.8] [Reference Citation Analysis]
619 Robbesyn F, Salvayre R, Negre-salvayre A. Dual Role of Oxidized LDL on the NF-KappaB Signaling Pathway. Free Radical Research 2009;38:541-51. [DOI: 10.1080/10715760410001665244] [Cited by in Crossref: 110] [Cited by in F6Publishing: 106] [Article Influence: 8.5] [Reference Citation Analysis]
620 Sithanandam G, Fornwald LW, Fields J, Anderson LM. Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549. Oncogene 2005;24:1847-59. [PMID: 15688028 DOI: 10.1038/sj.onc.1208381] [Cited by in Crossref: 58] [Cited by in F6Publishing: 56] [Article Influence: 3.4] [Reference Citation Analysis]
621 Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat Cell Biol. 2001;3:245-252. [PMID: 11231573 DOI: 10.1038/35060032] [Cited by in Crossref: 691] [Cited by in F6Publishing: 675] [Article Influence: 32.9] [Reference Citation Analysis]
622 Toth A, Kovacs K, Deres P, Halmosi R, Czopf L, Hanto K, Kalai T, Hideg K, Sumegi B, Toth K. Impact of a novel cardioprotective agent on the ischaemia-reperfusion-induced Akt kinase activation. Biochem Pharmacol 2003;66:2263-72. [PMID: 14609750 DOI: 10.1016/j.bcp.2003.08.007] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 0.8] [Reference Citation Analysis]
623 Aikin R, Rosenberg L, Maysinger D. Phosphatidylinositol 3-Kinase Signaling to Akt Mediates Survival in Isolated Canine Islets of Langerhans. Biochemical and Biophysical Research Communications 2000;277:455-61. [DOI: 10.1006/bbrc.2000.3664] [Cited by in Crossref: 37] [Cited by in F6Publishing: 39] [Article Influence: 1.7] [Reference Citation Analysis]
624 Tureckova J, Wilson EM, Cappalonga JL, Rotwein P. Insulin-like Growth Factor-mediated Muscle Differentiation. Journal of Biological Chemistry 2001;276:39264-70. [DOI: 10.1074/jbc.m104991200] [Cited by in Crossref: 142] [Cited by in F6Publishing: 54] [Article Influence: 6.8] [Reference Citation Analysis]
625 Gary DS, Mattson MP. Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis. J Neurochem 2001;76:1485-96. [PMID: 11238733 DOI: 10.1046/j.1471-4159.2001.00173.x] [Cited by in Crossref: 91] [Cited by in F6Publishing: 92] [Article Influence: 4.3] [Reference Citation Analysis]
626 Ito S, Sawada M, Haneda M, Fujii S, Oh-Hashi K, Kiuchi K, Takahashi M, Isobe K. Amyloid-beta peptides induce cell proliferation and macrophage colony-stimulating factor expression via the PI3-kinase/Akt pathway in cultured Ra2 microglial cells. FEBS Lett 2005;579:1995-2000. [PMID: 15792809 DOI: 10.1016/j.febslet.2005.02.048] [Cited by in Crossref: 15] [Cited by in F6Publishing: 17] [Article Influence: 0.9] [Reference Citation Analysis]
627 Foo RS, Mani K, Kitsis RN. Death begets failure in the heart. J Clin Invest 2005;115:565-71. [PMID: 15765138 DOI: 10.1172/JCI24569] [Cited by in Crossref: 194] [Cited by in F6Publishing: 114] [Article Influence: 11.4] [Reference Citation Analysis]
628 Chen J, Zhu H, Zhang Y, Cui MH, Han LY, Jia ZH, Wang L, Teng H, Miao LN. Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway. Mol Med Rep 2015;12:2622-8. [PMID: 25954860 DOI: 10.3892/mmr.2015.3740] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
629 Reiter CEN, Sandirasegarane L, Wolpert EB, Klinger M, Simpson IA, Barber AJ, Antonetti DA, Kester M, Gardner TW. Characterization of insulin signaling in rat retina in vivo and ex vivo. American Journal of Physiology-Endocrinology and Metabolism 2003;285:E763-74. [DOI: 10.1152/ajpendo.00507.2002] [Cited by in Crossref: 58] [Cited by in F6Publishing: 73] [Article Influence: 3.1] [Reference Citation Analysis]
630 Hersey P, Zhang XD. Overcoming resistance of cancer cells to apoptosis. J Cell Physiol 2003;196:9-18. [PMID: 12767037 DOI: 10.1002/jcp.10256] [Cited by in Crossref: 76] [Cited by in F6Publishing: 68] [Article Influence: 4.0] [Reference Citation Analysis]
631 Kim I, Oh JL, Ryu YS, So JN, Sessa WC, Walsh K, Koh GY. Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells. FASEB J 2002;16:126-8. [PMID: 11729102 DOI: 10.1096/fj.01-0556fje] [Cited by in Crossref: 75] [Cited by in F6Publishing: 77] [Article Influence: 3.6] [Reference Citation Analysis]
632 Patel NA, Kaneko S, Apostolatos HS, Bae SS, Watson JE, Davidowitz K, Chappell DS, Birnbaum MJ, Cheng JQ, Cooper DR. Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40. J Biol Chem 2005;280:14302-9. [PMID: 15684423 DOI: 10.1074/jbc.M411485200] [Cited by in Crossref: 90] [Cited by in F6Publishing: 57] [Article Influence: 5.3] [Reference Citation Analysis]
633 Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest. 2001;107:241-246. [PMID: 11160144 DOI: 10.1172/jci11991] [Cited by in Crossref: 855] [Cited by in F6Publishing: 342] [Article Influence: 40.7] [Reference Citation Analysis]
634 Ma J, Tsao TC, Hsi Y, Lin Y, Chen Y, Chen Y, Ho C, Kao J, Way T. Essential oil of Curcuma aromatica induces apoptosis in human non-small-cell lung carcinoma cells. Journal of Functional Foods 2016;22:101-12. [DOI: 10.1016/j.jff.2016.01.019] [Cited by in Crossref: 6] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
635 Shen W, Chen G, Dong R, Zhao R, Zheng S. MicroRNA-21/PTEN/Akt axis in the fibrogenesis of biliary atresia. Journal of Pediatric Surgery 2014;49:1738-41. [DOI: 10.1016/j.jpedsurg.2014.09.009] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 2.4] [Reference Citation Analysis]
636 Huang W, Guo L, Zhao M, Zhang D, Xu H, Nie Q. The Inhibition on MDFIC and PI3K/AKT Pathway Caused by miR-146b-3p Triggers Suppression of Myoblast Proliferation and Differentiation and Promotion of Apoptosis. Cells 2019;8:E656. [PMID: 31261950 DOI: 10.3390/cells8070656] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 5.7] [Reference Citation Analysis]
637 Sutaria D, Grandhi BK, Thakkar A, Wang J, Prabhu S. Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and sulforaphane drug combination regimen. Int J Oncol 2012;41:2260-8. [PMID: 23007664 DOI: 10.3892/ijo.2012.1636] [Cited by in Crossref: 42] [Cited by in F6Publishing: 34] [Article Influence: 4.2] [Reference Citation Analysis]
638 Björnström L, Sjöberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 2005;19:833-42. [PMID: 15695368 DOI: 10.1210/me.2004-0486] [Cited by in Crossref: 840] [Cited by in F6Publishing: 804] [Article Influence: 49.4] [Reference Citation Analysis]
639 Regula KM, Baetz D, Kirshenbaum LA. Nuclear Factor-κB Represses Hypoxia-Induced Mitochondrial Defects and Cell Death of Ventricular Myocytes. Circulation 2004;110:3795-802. [DOI: 10.1161/01.cir.0000150537.59754.55] [Cited by in Crossref: 47] [Cited by in F6Publishing: 27] [Article Influence: 2.6] [Reference Citation Analysis]
640 Yuan Z, Feldman RI, Sun M, Olashaw NE, Coppola D, Sussman GE, Shelley SA, Nicosia SV, Cheng JQ. Inhibition of JNK by Cellular Stress- and Tumor Necrosis Factor α-induced AKT2 through Activation of the NFκB Pathway in Human Epithelial Cells. Journal of Biological Chemistry 2002;277:29973-83. [DOI: 10.1074/jbc.m203636200] [Cited by in Crossref: 41] [Cited by in F6Publishing: 10] [Article Influence: 2.1] [Reference Citation Analysis]
641 Yi P, Lu FE, Chen G, Xu LJ, Wang KF. Molecular mechanism of insulin resistance induced by free fatty acids in 3T3-L1 adipocytes through targeting nuclear-kB p65. Shijie Huaren Xiaohua Zazhi 2007; 15(15): 1706-1712 [DOI: 10.11569/wcjd.v15.i15.1706] [Reference Citation Analysis]
642 Shi CS, Kehrl JH. PYK2 links G(q)alpha and G(13)alpha signaling to NF-kappa B activation. J Biol Chem 2001;276:31845-50. [PMID: 11435419 DOI: 10.1074/jbc.M101043200] [Cited by in Crossref: 45] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
643 Hsieh HL, Sun CC, Wu CB, Wu CY, Tung WH, Wang HH, Yang CM. Sphingosine 1-phosphate induces EGFR expression via Akt/NF-kappaB and ERK/AP-1 pathways in rat vascular smooth muscle cells. J Cell Biochem 2008;103:1732-46. [PMID: 17902169 DOI: 10.1002/jcb.21563] [Cited by in Crossref: 45] [Cited by in F6Publishing: 43] [Article Influence: 3.2] [Reference Citation Analysis]
644 Son DJ, Ha SJ, Song HS, Lim Y, Yun YP, Lee JW, Moon DC, Park YH, Park BS, Song MJ, Hong JT. Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression. J Pharmacol Exp Ther 2006;317:627-34. [PMID: 16401728 DOI: 10.1124/jpet.105.095901] [Cited by in Crossref: 51] [Cited by in F6Publishing: 46] [Article Influence: 3.2] [Reference Citation Analysis]
645 Linton MF, Moslehi JJ, Babaev VR. Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis. Int J Mol Sci 2019;20:E2703. [PMID: 31159424 DOI: 10.3390/ijms20112703] [Cited by in Crossref: 44] [Cited by in F6Publishing: 38] [Article Influence: 14.7] [Reference Citation Analysis]
646 Heng MC. Curcumin targeted signaling pathways: basis for anti-photoaging and anti-carcinogenic therapy: Curcumin targeted signaling pathways. International Journal of Dermatology 2010;49:608-22. [DOI: 10.1111/j.1365-4632.2010.04468.x] [Cited by in Crossref: 40] [Cited by in F6Publishing: 31] [Article Influence: 3.3] [Reference Citation Analysis]
647 Relić B, Bentires-alj M, Ribbens C, Franchimont N, Guerne P, Benoît V, Merville M, Bours V, Malaise MG. TNF-α Protects Human Primary Articular Chondrocytes from Nitric Oxide-Induced Apoptosis Via Nuclear Factor-κB. Lab Invest 2002;82:1661-72. [DOI: 10.1097/01.lab.0000041714.05322.c0] [Cited by in Crossref: 31] [Cited by in F6Publishing: 12] [Article Influence: 1.6] [Reference Citation Analysis]
648 McCubrey JA, Steelman LS, Franklin RA, Abrams SL, Chappell WH, Wong EW, Lehmann BD, Terrian DM, Basecke J, Stivala F, Libra M, Evangelisti C, Martelli AM. Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance. Adv Enzyme Regul 2007;47:64-103. [PMID: 17382374 DOI: 10.1016/j.advenzreg.2006.12.013] [Cited by in Crossref: 57] [Cited by in F6Publishing: 51] [Article Influence: 3.8] [Reference Citation Analysis]
649 Liu H, Zang C, Fenner MH, Liu D, Possinger K, Koeffler HP, Elstner E. Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18. Blood. 2006;107:3683-3692. [PMID: 16403907 DOI: 10.1182/blood-2005-05-2103] [Cited by in Crossref: 38] [Cited by in F6Publishing: 38] [Article Influence: 2.4] [Reference Citation Analysis]
650 Afaq F, Saleem M, Aziz MH, Mukhtar H. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion markers in CD-1 mouse skin by oleandrin. Toxicology and Applied Pharmacology 2004;195:361-9. [DOI: 10.1016/j.taap.2003.09.027] [Cited by in Crossref: 32] [Cited by in F6Publishing: 31] [Article Influence: 1.8] [Reference Citation Analysis]
651 Kamata H, Manabe T, Oka Si, Kamata K, Hirata H. Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops. FEBS Lett 2002;519:231-7. [PMID: 12023051 DOI: 10.1016/s0014-5793(02)02712-6] [Cited by in Crossref: 123] [Cited by in F6Publishing: 40] [Article Influence: 6.2] [Reference Citation Analysis]
652 Onorati F, Chen-Scarabelli C, Knight R, Stephanou A, Mohanti B, Santini F, Tessari M, Kini A, Narula J, Saravolatz L, Mazzucco A, Scarabelli T, Faggian G. Targeting urocortin signaling pathways to enhance cardioprotection: is it time to move from bench to bedside? Cardiovasc Drugs Ther 2013;27:451-63. [PMID: 23824484 DOI: 10.1007/s10557-013-6468-7] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.0] [Reference Citation Analysis]
653 Yoon SO, Park SJ, Yoon SY, Yun CH, Chung AS. Sustained production of H(2)O(2) activates pro-matrix metalloproteinase-2 through receptor tyrosine kinases/phosphatidylinositol 3-kinase/NF-kappa B pathway. J Biol Chem 2002;277:30271-82. [PMID: 12058032 DOI: 10.1074/jbc.M202647200] [Cited by in Crossref: 132] [Cited by in F6Publishing: 42] [Article Influence: 6.6] [Reference Citation Analysis]
654 Tong Q, Zheng L, Lin L, Li B, Wang D, Li D. Hypoxia-induced mitogenic factor promotes vascular adhesion molecule-1 expression via the PI-3K/Akt-NF-kappaB signaling pathway. Am J Respir Cell Mol Biol 2006;35:444-56. [PMID: 16709959 DOI: 10.1165/rcmb.2005-0424OC] [Cited by in Crossref: 29] [Cited by in F6Publishing: 13] [Article Influence: 1.8] [Reference Citation Analysis]
655 Denlinger CE, Rundall BK, Jones DR. Inhibition of phosphatidylinositol 3-kinase/Akt and histone deacetylase activity induces apoptosis in non-small cell lung cancer in vitro and in vivo. J Thorac Cardiovasc Surg 2005;130:1422-9. [PMID: 16256798 DOI: 10.1016/j.jtcvs.2005.06.051] [Cited by in Crossref: 24] [Cited by in F6Publishing: 22] [Article Influence: 1.4] [Reference Citation Analysis]
656 Liu W, Li Y, Zheng X, Zhang K, Du Z. Chemoprevention effects of a sulindac-based compound on TPA-induced skin inflammation in mice. Med Chem Commun 2015;6:1605-11. [DOI: 10.1039/c5md00227c] [Cited by in Crossref: 2] [Article Influence: 0.3] [Reference Citation Analysis]
657 Saadi S, Saari N, Ghazali HM, Mohammed AS, Abdul-hamid A, Nacer NE, Anwar F. Lipopeptides in promoting signals at surface/interface of micelles: Their roles in repairing cellular and nuclear damages. Food Bioscience 2022;46:101522. [DOI: 10.1016/j.fbio.2021.101522] [Reference Citation Analysis]
658 Wang T, Hu YC, Dong S, Fan M, Tamae D, Ozeki M, Gao Q, Gius D, Li JJ. Co-activation of ERK, NF-kappaB, and GADD45beta in response to ionizing radiation. J Biol Chem 2005;280:12593-601. [PMID: 15642734 DOI: 10.1074/jbc.M410982200] [Cited by in Crossref: 50] [Cited by in F6Publishing: 27] [Article Influence: 2.9] [Reference Citation Analysis]
659 Mao W, Iwai C, Keng PC, Vulapalli R, Liang C. Norepinephrine-induced oxidative stress causes PC-12 cell apoptosis by both endoplasmic reticulum stress and mitochondrial intrinsic pathway: inhibition of phosphatidylinositol 3-kinase survival pathway. American Journal of Physiology-Cell Physiology 2006;290:C1373-84. [DOI: 10.1152/ajpcell.00369.2005] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 1.9] [Reference Citation Analysis]
660 Okano J, Gaslightwala I, Birnbaum MJ, Rustgi AK, Nakagawa H. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation. J Biol Chem. 2000;275:30934-30942. [PMID: 10908564 DOI: 10.1074/jbc.m004112200] [Cited by in Crossref: 150] [Cited by in F6Publishing: 59] [Article Influence: 6.8] [Reference Citation Analysis]
661 Yan X, Shen H, Jiang H, Zhang C, Hu D, Wang J, Wu X. RETRACTED ARTICLE: External Qi of Yan Xin Qigong induces G2/M arrest and apoptosis of androgen-independent prostate cancer cells by inhibiting Akt and NF-κB pathways. Mol Cell Biochem 2008;310:227-34. [DOI: 10.1007/s11010-007-9684-2] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 1.4] [Reference Citation Analysis]
662 Akca H, Yenisoy S, Yanikoglu A, Ozes ON. Tumor necrosis factor-alpha-induced accumulation of tumor suppressor protein p53 and cyclin-dependent protein kinase inhibitory protein p21 is inhibited by insulin in ME-180S cells. Clin Chem Lab Med 2002;40:764-8. [PMID: 12392301 DOI: 10.1515/CCLM.2002.131] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.2] [Reference Citation Analysis]
663 Londhe VA, Nguyen HT, Jeng J, Li X, Li C, Tiozzo C, Zhu N, Minoo P. NF-kB induces lung maturation during mouse lung morphogenesis. Dev Dyn 2008;237:328-38. [DOI: 10.1002/dvdy.21413] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 1.7] [Reference Citation Analysis]
664 Maeda S, Nakajima K, Tohyama Y, Kohsaka S. Characteristic response of astrocytes to plasminogen/plasmin to upregulate transforming growth factor beta 3 (TGFbeta3) production/secretion through proteinase-activated receptor-1 (PAR-1) and the downstream phosphatidylinositol 3-kinase (PI3K)-Akt/PKB signaling cascade. Brain Res 2009;1305:1-13. [PMID: 19765562 DOI: 10.1016/j.brainres.2009.09.025] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 1.5] [Reference Citation Analysis]
665 Lizzul PF, Aphale A, Malaviya R, Sun Y, Masud S, Dombrovskiy V, Gottlieb AB. Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept. J Invest Dermatol 2005;124:1275-83. [PMID: 15955104 DOI: 10.1111/j.0022-202X.2005.23735.x] [Cited by in Crossref: 131] [Cited by in F6Publishing: 54] [Article Influence: 7.7] [Reference Citation Analysis]
666 Saibil SD, Jones RG, Deenick EK, Liadis N, Elford AR, Vainberg MG, Baerg H, Woodgett JR, Gerondakis S, Ohashi PS. CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. J Immunol 2007;178:2932-9. [PMID: 17312138 DOI: 10.4049/jimmunol.178.5.2932] [Cited by in Crossref: 37] [Cited by in F6Publishing: 40] [Article Influence: 2.5] [Reference Citation Analysis]
667 Suchowski K, Pöschinger T, Rehemtulla A, Stürzl M, Scheuer W. Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics. Neoplasia 2017;19:310-20. [PMID: 28285180 DOI: 10.1016/j.neo.2017.02.005] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.2] [Reference Citation Analysis]
668 De Martin R, Hoeth M, Hofer-Warbinek R, Schmid JA. The transcription factor NF-kappa B and the regulation of vascular cell function. Arterioscler Thromb Vasc Biol 2000;20:E83-8. [PMID: 11073859 DOI: 10.1161/01.atv.20.11.e83] [Cited by in Crossref: 196] [Cited by in F6Publishing: 90] [Article Influence: 8.9] [Reference Citation Analysis]
669 Xia Y, Lu RN, Li J. Angiogenic factors in chronic lymphocytic leukemia. Leuk Res 2012;36:1211-7. [PMID: 22727510 DOI: 10.1016/j.leukres.2012.05.021] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 1.5] [Reference Citation Analysis]
670 Kuo DH, Lai YS, Lo CY, Cheng AC, Wu H, Pan MH. Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice. J Agric Food Chem 2010;58:5777-83. [PMID: 20218615 DOI: 10.1021/jf100601r] [Cited by in Crossref: 46] [Cited by in F6Publishing: 46] [Article Influence: 3.8] [Reference Citation Analysis]
671 He M, Li A, Xu C, Wang S, Zhang M, Gu H, Yang Y, Tao H. Mechanisms of antiprostate cancer by gum mastic: NF-?B signal as target. Acta Pharmacologica Sinica 2007;28:446-52. [DOI: 10.1111/j.1745-7254.2007.00536.x] [Cited by in Crossref: 29] [Cited by in F6Publishing: 28] [Article Influence: 1.9] [Reference Citation Analysis]
672 Sudheerkumar P, Shiras A, Das G, Jagtap JC, Prasad V, Shastry P. Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas. Mol Carcinog 2008;47:126-36. [PMID: 17849421 DOI: 10.1002/mc.20372] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 1.0] [Reference Citation Analysis]
673 Bassères DS, Baldwin AS. Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression. Oncogene 2006;25:6817-30. [DOI: 10.1038/sj.onc.1209942] [Cited by in Crossref: 476] [Cited by in F6Publishing: 454] [Article Influence: 29.8] [Reference Citation Analysis]
674 Hashimoto T, Furuyashiki T, Sano T, Kihara K, Fukuda I, Ito W, Park P, Kanazawa K, Danno G, Ashida H. Apoptosis in the thymus after intraperitoneal injection of rats with Trp-P-1. Environ Mol Mutagen 2002;40:175-83. [DOI: 10.1002/em.10104] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.2] [Reference Citation Analysis]
675 Ni S, Wang H, Zhu X, Wan C, Xu J, Lu C, Xiao L, He J, Jiang C, Wang W, He Z. CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer. Oncotarget 2017;8:8010-21. [PMID: 28030829 DOI: 10.18632/oncotarget.14037] [Cited by in Crossref: 22] [Cited by in F6Publishing: 20] [Article Influence: 5.5] [Reference Citation Analysis]
676 Hsieh HL, Yen MH, Jou MJ, Yang CM. Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1. Cell Signal 2004;16:1163-76. [PMID: 15240011 DOI: 10.1016/j.cellsig.2004.03.021] [Cited by in Crossref: 60] [Cited by in F6Publishing: 57] [Article Influence: 3.5] [Reference Citation Analysis]
677 Barthel A, Klotz LO. Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress. Biol Chem 2005;386:207-16. [PMID: 15843166 DOI: 10.1515/BC.2005.026] [Cited by in Crossref: 67] [Cited by in F6Publishing: 18] [Article Influence: 3.9] [Reference Ci