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For: Osaki M, Oshimura M, Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis. 2004;9:667-676. [PMID: 15505410 DOI: 10.1023/b:appt.0000045801.15585.dd] [Cited by in Crossref: 773] [Cited by in F6Publishing: 355] [Article Influence: 45.5] [Reference Citation Analysis]
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7 Sehdev V, Lai JC, Bhushan A. Biochanin A Modulates Cell Viability, Invasion, and Growth Promoting Signaling Pathways in HER-2-Positive Breast Cancer Cells. J Oncol 2009;2009:121458. [PMID: 20169097 DOI: 10.1155/2009/121458] [Cited by in Crossref: 21] [Cited by in F6Publishing: 21] [Article Influence: 1.8] [Reference Citation Analysis]
8 Qi Q, Wang Q, Wang Z, Gao W, Gong X, Wang L. Visnagin inhibits cervical cancer cells proliferation through the induction of apoptosis and modulation of PI3K/AKT/mTOR and MAPK signaling pathway. Arabian Journal of Chemistry 2022;15:103684. [DOI: 10.1016/j.arabjc.2021.103684] [Reference Citation Analysis]
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12 Zhang C, Chen M, Tao Q, Chi Z. Cobalt chloride-stimulated hypoxia promotes the proliferation of cholesteatoma keratinocytes via the PI3K/Akt signaling pathway. Int J Med Sci 2021;18:3403-11. [PMID: 34522167 DOI: 10.7150/ijms.60617] [Reference Citation Analysis]
13 Woo JS, Choo GS, Yoo ES, Kim SH, Lee JH, Han SH, Kim HJ, Jung SH, Park YS, Kim BS, Kim SK, Park BK, Cho SD, Nam JS, Choi CS, Che JH, Jung JY. Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM. Mol Med Rep 2020;22:4877-89. [PMID: 33174048 DOI: 10.3892/mmr.2020.11572] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
14 Du Z, Gao W, Sun J, Li Y, Sun Y, Chen T, Ge S, Guo W. Identification of long non‑coding RNA‑mediated transcriptional dysregulation triplets reveals global patterns and prognostic biomarkers for ER+/PR+, HER2‑ and triple negative breast cancer. Int J Mol Med 2019;44:1015-25. [PMID: 31257479 DOI: 10.3892/ijmm.2019.4261] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
15 Bi L, Chen J, Yuan X, Jiang Z, Chen W. Salvianolic acid A positively regulates PTEN protein level and inhibits growth of A549 lung cancer cells. Biomed Rep 2013;1:213-7. [PMID: 24648921 DOI: 10.3892/br.2012.33] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 1.8] [Reference Citation Analysis]
16 Chetty C, Lakka SS, Bhoopathi P, Rao JS. MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 Lung cancer cells. Int J Cancer. 2010;127:1081-1095. [PMID: 20027628 DOI: 10.1002/ijc.25134] [Cited by in Crossref: 122] [Cited by in F6Publishing: 128] [Article Influence: 10.2] [Reference Citation Analysis]
17 Beauséjour M, Noël D, Thibodeau S, Bouchard V, Harnois C, Beaulieu JF, Demers MJ, Vachon PH. Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes. Apoptosis 2012;17:566-78. [PMID: 22402981 DOI: 10.1007/s10495-012-0713-6] [Cited by in Crossref: 38] [Cited by in F6Publishing: 32] [Article Influence: 3.8] [Reference Citation Analysis]
18 Tang M, Odejinmi SI, Vankayalapati H, Wierenga KJ, Lai K. Innovative therapy for Classic Galactosemia - tale of two HTS. Mol Genet Metab 2012;105:44-55. [PMID: 22018723 DOI: 10.1016/j.ymgme.2011.09.028] [Cited by in Crossref: 38] [Cited by in F6Publishing: 34] [Article Influence: 3.5] [Reference Citation Analysis]
19 Daisy Precilla S, Biswas I, Kuduvalli SS, Anitha TS. Crosstalk between PI3K/AKT/mTOR and WNT/β-Catenin signaling in GBM - Could combination therapy checkmate the collusion? Cell Signal 2022;:110350. [PMID: 35525406 DOI: 10.1016/j.cellsig.2022.110350] [Reference Citation Analysis]
20 Deng Q, Yu X, Xiao L, Hu Z, Luo X, Tao Y, Yang L, Liu X, Chen H, Ding Z, Feng T, Tang Y, Weng X, Gao J, Yi W, Bode AM, Dong Z, Liu J, Cao Y. Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway. Cell Death Dis 2013;4:e804. [PMID: 24052072 DOI: 10.1038/cddis.2013.324] [Cited by in Crossref: 34] [Cited by in F6Publishing: 39] [Article Influence: 3.8] [Reference Citation Analysis]
21 Wang X, Gao P, Lin F, Long M, Weng Y, Ouyang Y, Liu L, Wei J, Chen X, He T, Zhang H, Dong K. Wilms' tumour suppressor gene 1 (WT1) is involved in the carcinogenesis of Lung cancer through interaction with PI3K/Akt pathway. Cancer Cell Int 2013;13:114. [PMID: 24228711 DOI: 10.1186/1475-2867-13-114] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 1.3] [Reference Citation Analysis]
22 Fu-Jun L, Shao-Hua J, Xiao-Fang S. Differential proteomic analysis of pathway biomarkers in human breast cancer by integrated bioinformatics. Oncol Lett 2012;4:1097-103. [PMID: 23162659 DOI: 10.3892/ol.2012.881] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
23 Sun Y, Ma C, Halgamuge S. The node-weighted Steiner tree approach to identify elements of cancer-related signaling pathways. BMC Bioinformatics 2017;18:551. [PMID: 29297291 DOI: 10.1186/s12859-017-1958-4] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
24 Carper MB, Denvir J, Boskovic G, Primerano DA, Claudio PP. RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells. Genes Cancer 2014;5:420-35. [PMID: 25568667 DOI: 10.18632/genesandcancer.43] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 1.6] [Reference Citation Analysis]
25 Choo GS, Lee HN, Shin SA, Kim HJ, Jung JY. Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression. Mar Drugs 2016;14:E126. [PMID: 27399727 DOI: 10.3390/md14070126] [Cited by in Crossref: 35] [Cited by in F6Publishing: 31] [Article Influence: 5.8] [Reference Citation Analysis]
26 Hu Y, Sun H, Owens RT, Gu Z, Wu J, Chen YQ, O'Flaherty JT, Edwards IJ. Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer. Neoplasia 2010;12:826-36. [PMID: 20927321 DOI: 10.1593/neo.10586] [Cited by in Crossref: 47] [Cited by in F6Publishing: 48] [Article Influence: 4.3] [Reference Citation Analysis]
27 Zhang H, Dan W, He Q, Guo J, Dai S, Hui X, Meng P, Cao Q, Yun W, Guo X. Exploring the Biological Mechanism of Huang Yam in Treating Tumors and Preventing Antitumor Drug-Induced Cardiotoxicity Using Network Pharmacology and Molecular Docking Technology. Evid Based Complement Alternat Med 2021;2021:9988650. [PMID: 34484411 DOI: 10.1155/2021/9988650] [Reference Citation Analysis]
28 Kashani B, Zandi Z, Kaveh V, Pourbagheri-Sigaroodi A, Ghaffari SH, Bashash D. Small molecules with huge impacts: the role of miRNA-regulated PI3K pathway in human malignancies. Mol Biol Rep 2021;48:8045-59. [PMID: 34689281 DOI: 10.1007/s11033-021-06739-6] [Reference Citation Analysis]
29 He Y, Cai Y, Sun T, Zhang L, Irwin MG, Xu A, Xia Z, Shao A. MicroRNA-503 Exacerbates Myocardial Ischemia/Reperfusion Injury via Inhibiting PI3K/Akt- and STAT3-Dependent Prosurvival Signaling Pathways. Oxidative Medicine and Cellular Longevity 2022;2022:1-17. [DOI: 10.1155/2022/3449739] [Reference Citation Analysis]
30 Chhetri DR. Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases. Front Pharmacol 2019;10:1172. [PMID: 31680956 DOI: 10.3389/fphar.2019.01172] [Cited by in Crossref: 25] [Cited by in F6Publishing: 19] [Article Influence: 8.3] [Reference Citation Analysis]
31 Minini M, Senni A, Unfer V, Bizzarri M. The Key Role of IP6K: A Novel Target for Anticancer Treatments? Molecules 2020;25:E4401. [PMID: 32992691 DOI: 10.3390/molecules25194401] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
32 Hernandez AR, Kemp KM, Burke SN, Buford TW, Carter CS. Influence of Aging, Macronutrient Composition and Time-Restricted Feeding on the Fischer344 x Brown Norway Rat Gut Microbiota. Nutrients 2022;14:1758. [DOI: 10.3390/nu14091758] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
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34 Vo BT, Morton D Jr, Komaragiri S, Millena AC, Leath C, Khan SA. TGF-β effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway. Endocrinology 2013;154:1768-79. [PMID: 23515290 DOI: 10.1210/en.2012-2074] [Cited by in Crossref: 119] [Cited by in F6Publishing: 121] [Article Influence: 13.2] [Reference Citation Analysis]
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37 Bi L, Yan X, Yang Y, Qian L, Tian Y, Mao JH, Chen W. The component formula of Salvia miltiorrhiza and Panax ginseng induces apoptosis and inhibits cell invasion and migration through targeting PTEN in lung cancer cells. Oncotarget. 2017;8:101599-101613. [PMID: 29254189 DOI: 10.18632/oncotarget.21354] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 2.4] [Reference Citation Analysis]
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41 Takao T, Asanoma K, Tsunematsu R, Kato K, Wake N. The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway. J Biol Chem 2012;287:42685-94. [PMID: 23071113 DOI: 10.1074/jbc.M112.388777] [Cited by in Crossref: 28] [Cited by in F6Publishing: 16] [Article Influence: 2.8] [Reference Citation Analysis]
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46 Liao CY, Lee CC, Tsai CC, Hsueh CW, Wang CC, Chen IH, Tsai MK, Liu MY, Hsieh AT, Su KJ. Novel Investigations of Flavonoids as Chemopreventive Agents for Hepatocellular Carcinoma. Biomed Res Int. 2015;2015:840542. [PMID: 26858957 DOI: 10.1155/2015/840542] [Cited by in Crossref: 28] [Cited by in F6Publishing: 26] [Article Influence: 4.0] [Reference Citation Analysis]
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48 Yan H, Peng X, Xu H, Zhu J, Deng C. Inhibition of Aortic Intimal Hyperplasia and Vascular Smooth Muscle Proliferation and Extracellular Matrix Protein Expressions by Astragalus-Angelica Combination. Evid Based Complement Alternat Med 2018;2018:1508637. [PMID: 30186350 DOI: 10.1155/2018/1508637] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.3] [Reference Citation Analysis]
49 Al-Wahab Z, Tebbe C, Chhina J, Dar SA, Morris RT, Ali-Fehmi R, Giri S, Munkarah AR, Rattan R. Dietary energy balance modulates ovarian cancer progression and metastasis. Oncotarget 2014;5:6063-75. [PMID: 25026276 DOI: 10.18632/oncotarget.2168] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 3.1] [Reference Citation Analysis]
50 Bao F, Kang X, Xie Q, Wu J. HIF-α/PKM2 and PI3K-AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal HT22 cells. Exp Ther Med 2019;17:63-70. [PMID: 30651766 DOI: 10.3892/etm.2018.6956] [Cited by in F6Publishing: 3] [Reference Citation Analysis]
51 Faramarzi F, Zafari P, Alimohammadi M, Moonesi M, Rafiei A, Bekeschus S, Szewczyk-golec K. Cold Physical Plasma in Cancer Therapy: Mechanisms, Signaling, and Immunity. Oxidative Medicine and Cellular Longevity 2021;2021:1-19. [DOI: 10.1155/2021/9916796] [Reference Citation Analysis]
52 Gonzalez L, Qian AS, Tahir U, Yu P, Trigatti BL. Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice. Int J Mol Sci 2017;18:E2721. [PMID: 29244772 DOI: 10.3390/ijms18122721] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 2.4] [Reference Citation Analysis]
53 Ali M, Raghunathan V, Li JY, Murphy CJ, Thomasy SM. Biomechanical relationships between the corneal endothelium and Descemet's membrane. Exp Eye Res 2016;152:57-70. [PMID: 27639516 DOI: 10.1016/j.exer.2016.09.004] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 3.0] [Reference Citation Analysis]
54 Huang G, Yang Y, Lv M, Huang T, Zhan X, Kang W, Hou J. Novel lncRNA SFTA1P Promotes Tumor Growth by Down-Regulating miR-4766-5p via PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma. Onco Targets Ther 2020;13:9759-70. [PMID: 33061455 DOI: 10.2147/OTT.S248660] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
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56 Krupkova O, Handa J, Hlavna M, Klasen J, Ospelt C, Ferguson SJ, Wuertz-Kozak K. The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress. Oxid Med Cell Longev 2016;2016:7031397. [PMID: 27119009 DOI: 10.1155/2016/7031397] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 4.3] [Reference Citation Analysis]
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59 Parsons RB, Facey PD. Nicotinamide N-Methyltransferase: An Emerging Protagonist in Cancer Macro(r)evolution. Biomolecules 2021;11:1418. [PMID: 34680055 DOI: 10.3390/biom11101418] [Reference Citation Analysis]
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