BPG is committed to discovery and dissemination of knowledge
Cited by in F6Publishing
For: Leung D, Abbenante G, Fairlie DP. Protease inhibitors: current status and future prospects. J Med Chem 2000;43:305-41. [PMID: 10669559 DOI: 10.1021/jm990412m] [Cited by in Crossref: 614] [Cited by in F6Publishing: 586] [Article Influence: 27.9] [Reference Citation Analysis]
Number Citing Articles
1 De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT. Design of Weakly Basic Thrombin Inhibitors Incorporating Novel P1 Binding Functions:  Molecular and X-ray Crystallographic Studies. Biochemistry 2003;42:9013-21. [DOI: 10.1021/bi020512l] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
2 Iley J, Moreira R, Martins L, Guedes RC, Soares CM. The Bsmoc group as a novel scaffold for the design of irreversible inhibitors of cysteine proteases. Bioorganic & Medicinal Chemistry Letters 2006;16:2738-41. [DOI: 10.1016/j.bmcl.2006.02.007] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
3 Rachel KV, Solmon KS, Kiranmayi P, Reddy IB, Prasad DS. In silico modeling and docking studies of Soap Nut Trypsin Inhibitor. Process Biochemistry 2012;47:453-9. [DOI: 10.1016/j.procbio.2011.11.026] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
4 Kemami Wangun HV, Ishida K, Hertweck C. Epicoccalone, a Coumarin-Type Chymotrypsin Inhibitor, and Isobenzofuran Congeners from an Epicoccum sp. Associated with a Tree Fungus. Eur J Org Chem 2008;2008:3781-4. [DOI: 10.1002/ejoc.200800447] [Cited by in Crossref: 23] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
5 Terai T, Kikuchi K, Iwasawa S, Kawabe T, Hirata Y, Urano Y, Nagano T. Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe. J Am Chem Soc 2006;128:6938-46. [DOI: 10.1021/ja060729t] [Cited by in Crossref: 137] [Cited by in F6Publishing: 106] [Article Influence: 8.6] [Reference Citation Analysis]
6 Pešić M, López C, Álvaro G. Chloroperoxidase catalyzed oxidation of Cbz-ethanolamine to Cbz-glycinal. Biochemical Engineering Journal 2012;67:218-24. [DOI: 10.1016/j.bej.2012.06.019] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
7 Citron M. Strategies for disease modification in Alzheimer's disease. Nat Rev Neurosci 2004;5:677-85. [PMID: 15322526 DOI: 10.1038/nrn1495] [Cited by in Crossref: 305] [Cited by in F6Publishing: 287] [Article Influence: 16.9] [Reference Citation Analysis]
8 Leung D, Schroder K, White H, Fang NX, Stoermer MJ, Abbenante G, Martin JL, Young PR, Fairlie DP. Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. J Biol Chem 2001;276:45762-71. [PMID: 11581268 DOI: 10.1074/jbc.M107360200] [Cited by in Crossref: 231] [Cited by in F6Publishing: 85] [Article Influence: 11.0] [Reference Citation Analysis]
9 Hu J, Liu F, Feng N, Ju H. Peptide codes for multiple protease activity assay via high-resolution mass spectrometric quantitation. Rapid Commun Mass Spectrom 2016;30 Suppl 1:196-201. [PMID: 27539438 DOI: 10.1002/rcm.7631] [Cited by in Crossref: 4] [Article Influence: 0.7] [Reference Citation Analysis]
10 Suzuki F, Murakami K, Nakamura Y, Inagami T. Renin. Handbook of Proteolytic Enzymes. Elsevier; 2004. pp. 54-61. [DOI: 10.1016/b978-0-12-079611-3.50018-5] [Cited by in Crossref: 2] [Article Influence: 0.1] [Reference Citation Analysis]
11 Smith AB 3rd, Charnley AK, Harada H, Beiger JJ, Cantin LD, Kenesky CS, Hirschmann R, Munshi S, Olsen DB, Stahlhut MW, Schleif WA, Kuo LC. Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains. Bioorg Med Chem Lett 2006;16:859-63. [PMID: 16298527 DOI: 10.1016/j.bmcl.2005.11.011] [Cited by in Crossref: 19] [Cited by in F6Publishing: 14] [Article Influence: 1.1] [Reference Citation Analysis]
12 Chen D, Hackbarth C, Ni ZJ, Wu C, Wang W, Jain R, He Y, Bracken K, Weidmann B, Patel DV, Trias J, White RJ, Yuan Z. Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach. Antimicrob Agents Chemother 2004;48:250-61. [PMID: 14693547 DOI: 10.1128/AAC.48.1.250-261.2004] [Cited by in Crossref: 47] [Cited by in F6Publishing: 8] [Article Influence: 2.6] [Reference Citation Analysis]
13 Wu M, Wang X, Wang K, Guo Z. An ultrasensitive fluorescent nanosensor for trypsin based on upconversion nanoparticles. Talanta 2017;174:797-802. [PMID: 28738656 DOI: 10.1016/j.talanta.2017.07.013] [Cited by in Crossref: 19] [Cited by in F6Publishing: 15] [Article Influence: 3.8] [Reference Citation Analysis]
14 Xu Z, Liu R, Guan H. Dual-target inhibitor screening against thrombin and factor Xa simultaneously by mass spectrometry. Anal Chim Acta 2017;990:1-10. [PMID: 29029731 DOI: 10.1016/j.aca.2017.07.063] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
15 Sirisoma N, Kasibhatla S, Nguyen B, Pervin A, Wang Y, Claassen G, Tseng B, Drewe J, Cai SX. Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group. Bioorganic & Medicinal Chemistry 2006;14:7761-73. [DOI: 10.1016/j.bmc.2006.08.002] [Cited by in Crossref: 28] [Cited by in F6Publishing: 22] [Article Influence: 1.8] [Reference Citation Analysis]
16 Wannberg J, Ersmark K, Larhed M. Microwave-Accelerated Synthesis of Protease Inhibitors. In: Larhed M, Olofssonq K, editors. Microwave Methods in Organic Synthesis. Springer Berlin Heidelberg; 2006. pp. 167-98. [DOI: 10.1007/128_067] [Cited by in Crossref: 15] [Cited by in F6Publishing: 11] [Reference Citation Analysis]
17 Le GT, Abbenante G, Madala PK, Hoang HN, Fairlie DP. Organic Azide Inhibitors of Cysteine Proteases. J Am Chem Soc 2006;128:12396-7. [DOI: 10.1021/ja0637649] [Cited by in Crossref: 18] [Cited by in F6Publishing: 14] [Article Influence: 1.1] [Reference Citation Analysis]
18 Valente E, Gomes JRB, Moreira R, Iley J. Kinetics and Mechanism of Hydrolysis of N -Acyloxymethyl Derivatives of Azetidin-2-one. J Org Chem 2004;69:3359-67. [DOI: 10.1021/jo0358123] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 0.6] [Reference Citation Analysis]
19 Li S, Li Z, Li H, Zhong C, Huang K, Chen B, Huang L, Lin X, Liu Q, Yao H. Synthesis, biological evaluation, pharmacokinetic studies and molecular docking of 4'''-acetyl-delicaflavone as antitumor agents. Bioorg Chem 2022;120:105638. [PMID: 35121550 DOI: 10.1016/j.bioorg.2022.105638] [Reference Citation Analysis]
20 Kim JH, Mullin CA. Antifeedant effects of proteinase inhibitors on feeding behaviors of adult western corn rootworm (Diabrotica virgifera virgifera). J Chem Ecol 2003;29:795-810. [PMID: 12775144 DOI: 10.1023/a:1022919413625] [Cited by in Crossref: 10] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
21 Benedetti F, Berti F, Norbedo S. Epoxyalcohol Route to Hydroxyethylene Dipeptide Isosteres. Stereodivergent Synthesis of the Diamino Alcohol Core of Ritonavir and Its C-2 Epimer. J Org Chem 2002;67:8635-43. [DOI: 10.1021/jo025616g] [Cited by in Crossref: 22] [Cited by in F6Publishing: 19] [Article Influence: 1.1] [Reference Citation Analysis]
22 Dastan T, Kocyigit UM, Durna Dastan S, Canturk Kilickaya P, Taslimi P, Cevik O, Koparir M, Orek C, Gulçin İ, Cetin A. Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(α-aminoalkyl)phosphinic acid derivatives against human breast cancer. J Biochem Mol Toxicol 2017;31:e21971. [DOI: 10.1002/jbt.21971] [Cited by in Crossref: 33] [Cited by in F6Publishing: 33] [Article Influence: 6.6] [Reference Citation Analysis]
23 Citron M. Secretases as targets for the treatment of Alzheimer’s disease. Molecular Medicine Today 2000;6:392-7. [DOI: 10.1016/s1357-4310(00)01759-7] [Cited by in Crossref: 28] [Cited by in F6Publishing: 8] [Article Influence: 1.3] [Reference Citation Analysis]
24 Janin YL. Peptides with anticancer use or potential. Amino Acids 2003;25:1-40. [DOI: 10.1007/s00726-002-0349-x] [Cited by in Crossref: 45] [Cited by in F6Publishing: 37] [Article Influence: 2.4] [Reference Citation Analysis]
25 Löser R, Pietzsch J. Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes. Front Chem 2015;3:37. [PMID: 26157794 DOI: 10.3389/fchem.2015.00037] [Cited by in Crossref: 42] [Cited by in F6Publishing: 39] [Article Influence: 6.0] [Reference Citation Analysis]
26 Yanchunas J Jr, Langley DR, Tao L, Rose RE, Friborg J, Colonno RJ, Doyle ML. Molecular basis for increased susceptibility of isolates with atazanavir resistance-conferring substitution I50L to other protease inhibitors. Antimicrob Agents Chemother 2005;49:3825-32. [PMID: 16127059 DOI: 10.1128/AAC.49.9.3825-3832.2005] [Cited by in Crossref: 40] [Cited by in F6Publishing: 17] [Article Influence: 2.4] [Reference Citation Analysis]
27 Avalos M, Babiano R, Cintas P, Hursthouse MB, Jiménez JL, Light ME, López I, Palacios JC, Silvero G. Three- and Four-Membered Rings from Cycloadditions of 1,3-Thiazolium-4-olates and Aldehydes. Chem Eur J 2001;7:3033-42. [DOI: 10.1002/1521-3765(20010716)7:14<3033::aid-chem3033>3.0.co;2-f] [Cited by in Crossref: 12] [Article Influence: 0.6] [Reference Citation Analysis]
28 Rodríguez Ortega MPG, Montejo M, López González JJ. Interaction models of the Si(OH)2 functionality with Zn2+ cation in simplified biological environments: a DFT study. Struct Chem 2014;25:127-38. [DOI: 10.1007/s11224-013-0258-5] [Cited by in Crossref: 3] [Article Influence: 0.3] [Reference Citation Analysis]
29 Kotb E, Abouel-hawa MI, Tohamy EY, El-msalamy K. Purification of toxic protease from Brevibacterium otitidis KB76 with both metal and hydrosulfuryl at the active site. Biologia 2013;68:797-802. [DOI: 10.2478/s11756-013-0224-0] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
30 Maliar T, Jedinák A, Kadrabová J, Šturdík E. Structural aspects of flavonoids as trypsin inhibitors. European Journal of Medicinal Chemistry 2004;39:241-8. [DOI: 10.1016/j.ejmech.2003.12.003] [Cited by in Crossref: 59] [Cited by in F6Publishing: 51] [Article Influence: 3.3] [Reference Citation Analysis]
31 Pomarnacka E, Kornicka A. Synthesis and in vitro anticancer and anti-HIV evaluation of new 2-mercaptobenzenesulfonamides. Il Farmaco 2001;56:571-7. [DOI: 10.1016/s0014-827x(01)01095-3] [Cited by in Crossref: 20] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
32 Tossi A, Benedetti F, Norbedo S, Skrbec D, Berti F, Romeo D. Small hydroxyethylene-based peptidomimetics inhibiting both HIV-1 and C. albicans aspartic proteases. Bioorg Med Chem 2003;11:4719-27. [PMID: 14556787 DOI: 10.1016/j.bmc.2003.08.004] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 0.8] [Reference Citation Analysis]
33 Bendre AD, Suresh CG, Shanmugam D, Ramasamy S. Structural insights into the unique inhibitory mechanism of Kunitz type trypsin inhibitor from Cicer arietinum L. J Biomol Struct Dyn 2019;37:2669-77. [PMID: 30052127 DOI: 10.1080/07391102.2018.1494633] [Cited by in Crossref: 9] [Cited by in F6Publishing: 4] [Article Influence: 2.3] [Reference Citation Analysis]
34 Kambe T, Correia BE, Niphakis MJ, Cravatt BF. Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc 2014;136:10777-82. [PMID: 25045785 DOI: 10.1021/ja505517t] [Cited by in Crossref: 67] [Cited by in F6Publishing: 57] [Article Influence: 8.4] [Reference Citation Analysis]
35 Brass S, Chan N, Gerlach C, Luksch T, Böttcher J, Diederich WE. Synthesis of 2,3,4,7-tetrahydro-1H-azepines as privileged ligand scaffolds for the design of aspartic protease inhibitors via a ring-closing metathesis approach. Journal of Organometallic Chemistry 2006;691:5406-22. [DOI: 10.1016/j.jorganchem.2006.09.031] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 0.8] [Reference Citation Analysis]
36 Lang SA, Kozyukov AV, Balakin KV, Skorenko AV, Ivashchenko AA, Savchuk NP. Classification scheme for the design of serine protease targeted compound libraries. J Comput Aided Mol Des 2002;16:803-7. [PMID: 12825792 DOI: 10.1023/a:1023832728547] [Cited by in Crossref: 8] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
37 Ferraboschi P, Colombo D, Legnani L, Toma L, Grisenti P, Vistoli G, Meneghetti F. Crystallographic, spectroscopic, and theoretical investigation of the efficiently separated 21R and 21S-diastereoisomers of argatroban. Chirality 2013;25:871-82. [PMID: 23966356 DOI: 10.1002/chir.22228] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
38 Tarazi H, Odeh RA, Al-qawasmeh R, Yousef IA, Voelter W, Al-tel TH. Design, synthesis and SAR analysis of potent BACE1 inhibitors: Possible lead drug candidates for Alzheimer's disease. European Journal of Medicinal Chemistry 2017;125:1213-24. [DOI: 10.1016/j.ejmech.2016.11.021] [Cited by in Crossref: 13] [Cited by in F6Publishing: 10] [Article Influence: 2.6] [Reference Citation Analysis]
39 Reding M. Recent developments in hepatitis C antiviral research 1999 - 2000. Expert Opinion on Therapeutic Patents 2005;10:1201-20. [DOI: 10.1517/13543776.10.8.1201] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
40 Brzozowski Z, Saczewski F. A new type of mixed anhydride and its applications to the synthesis of 7-substituted 8-chloro-5,5-dioxoimidazo[1,2-b][1,4,2]benzodithiazines with in vitro antitumor activity. J Med Chem 2002;45:430-7. [PMID: 11784147 DOI: 10.1021/jm010953n] [Cited by in Crossref: 29] [Cited by in F6Publishing: 23] [Article Influence: 1.5] [Reference Citation Analysis]
41 Nunthanavanit P, Anthony NG, Johnston BF, Mackay SP, Ungwitayatorn J. 3D-QSAR studies on chromone derivatives as HIV-1 protease inhibitors: application of molecular field analysis. Arch Pharm (Weinheim) 2008;341:357-64. [PMID: 18442018 DOI: 10.1002/ardp.200700229] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
42 Young RJ. The successful quest for oral factor Xa inhibitors; learnings for all of medicinal chemistry? Bioorganic & Medicinal Chemistry Letters 2011;21:6228-35. [DOI: 10.1016/j.bmcl.2011.08.119] [Cited by in Crossref: 17] [Cited by in F6Publishing: 13] [Article Influence: 1.5] [Reference Citation Analysis]
43 Volonterio A, Bravo P, Moussier N, Zanda M. Solid-phase synthesis of partially-modified retro and retro-inverso ψ[NHCH(CF3)]-peptides. Tetrahedron Letters 2000;41:6517-21. [DOI: 10.1016/s0040-4039(00)01044-3] [Cited by in Crossref: 17] [Article Influence: 0.8] [Reference Citation Analysis]
44 Wise SG, Weiss AS. Tropoelastin. Int J Biochem Cell Biol 2009;41:494-7. [PMID: 18468477 DOI: 10.1016/j.biocel.2008.03.017] [Cited by in Crossref: 155] [Cited by in F6Publishing: 133] [Article Influence: 11.1] [Reference Citation Analysis]
45 Korda A, Wróbel Z, Gwardiak K. An efficient route from trifluoroacetates to water soluble free amines using Diaion HP-20. Amino Acids 2006;30:95-8. [PMID: 16049641 DOI: 10.1007/s00726-005-0228-3] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
46 Patterson AW, Wood WJ, Ellman JA. Substrate activity screening (SAS): a general procedure for the preparation and screening of a fragment-based non-peptidic protease substrate library for inhibitor discovery. Nat Protoc 2007;2:424-33. [PMID: 17406604 DOI: 10.1038/nprot.2007.28] [Cited by in Crossref: 30] [Cited by in F6Publishing: 27] [Article Influence: 2.0] [Reference Citation Analysis]
47 Suen JY, Cotterell A, Lohman RJ, Lim J, Han A, Yau MK, Liu L, Cooper MA, Vesey DA, Fairlie DP. Pathway-selective antagonism of proteinase activated receptor 2. Br J Pharmacol 2014;171:4112-24. [PMID: 24821440 DOI: 10.1111/bph.12757] [Cited by in Crossref: 43] [Cited by in F6Publishing: 42] [Article Influence: 5.4] [Reference Citation Analysis]
48 Evans MJ, Cravatt BF. Mechanism-based profiling of enzyme families. Chem Rev 2006;106:3279-301. [PMID: 16895328 DOI: 10.1021/cr050288g] [Cited by in Crossref: 463] [Cited by in F6Publishing: 428] [Article Influence: 30.9] [Reference Citation Analysis]
49 Singh S, Sieburth SM. Serine protease inhibition by a silanediol peptidomimetic. Org Lett 2012;14:4422-5. [PMID: 22894760 DOI: 10.1021/ol301933n] [Cited by in Crossref: 34] [Cited by in F6Publishing: 26] [Article Influence: 3.4] [Reference Citation Analysis]
50 Lee S, Yu JS, Lee SR, Kim KH. Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis. Nat Prod Rep 2021. [PMID: 34608478 DOI: 10.1039/d1np00049g] [Reference Citation Analysis]
51 Babič A, Sova M, Gobec S, Pečar S. Epoxide opening with amino acids: improved synthesis of hydroxyethylamine dipeptide isosteres. Tetrahedron Letters 2006;47:1733-5. [DOI: 10.1016/j.tetlet.2006.01.058] [Cited by in Crossref: 14] [Cited by in F6Publishing: 9] [Article Influence: 0.9] [Reference Citation Analysis]
52 Huang L, Ellman JA. General solid-phase method to prepare novel cyclic ketone inhibitors of the cysteine protease cruzain. Bioorganic & Medicinal Chemistry Letters 2002;12:2993-6. [DOI: 10.1016/s0960-894x(02)00619-4] [Cited by in Crossref: 11] [Cited by in F6Publishing: 2] [Article Influence: 0.6] [Reference Citation Analysis]
53 Gobec S, Plantan I, Mravljak J, Svajger U, Wilson RA, Besra GS, Soares SL, Appelberg R, Kikelj D. Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall. Eur J Med Chem 2007;42:54-63. [PMID: 17010479 DOI: 10.1016/j.ejmech.2006.08.007] [Cited by in Crossref: 33] [Cited by in F6Publishing: 28] [Article Influence: 2.1] [Reference Citation Analysis]
54 Iserloh U, Pan J, Stamford A, Kennedy M, Zhang Q, Zhang L, Parker E, Mchugh N, Favreau L, Strickland C, Voigt J. Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor. Bioorganic & Medicinal Chemistry Letters 2008;18:418-22. [DOI: 10.1016/j.bmcl.2007.10.053] [Cited by in Crossref: 54] [Cited by in F6Publishing: 48] [Article Influence: 3.9] [Reference Citation Analysis]
55 Kok WM. New developments in flavivirus drug discovery. Expert Opin Drug Discov 2016;11:433-45. [PMID: 26966889 DOI: 10.1517/17460441.2016.1160887] [Cited by in Crossref: 28] [Cited by in F6Publishing: 28] [Article Influence: 4.7] [Reference Citation Analysis]
56 Aoki S, Kimura E. Zinc Hydrolases. Comprehensive Coordination Chemistry II. Elsevier; 2003. pp. 601-40. [DOI: 10.1016/b0-08-043748-6/08139-1] [Cited by in Crossref: 15] [Article Influence: 0.8] [Reference Citation Analysis]
57 Tuccinardi T, Martinelli A, Nuti E, Carelli P, Balzano F, Uccello-Barretta G, Murphy G, Rossello A. Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides. Bioorg Med Chem 2006;14:4260-76. [PMID: 16483784 DOI: 10.1016/j.bmc.2006.01.056] [Cited by in Crossref: 57] [Cited by in F6Publishing: 51] [Article Influence: 3.6] [Reference Citation Analysis]
58 Motwani HV, De Rosa M, Odell LR, Hallberg A, Larhed M. Aspartic protease inhibitors containing tertiary alcohol transition-state mimics. Eur J Med Chem 2015;90:462-90. [PMID: 25481814 DOI: 10.1016/j.ejmech.2014.11.036] [Cited by in Crossref: 18] [Cited by in F6Publishing: 11] [Article Influence: 2.3] [Reference Citation Analysis]
59 Hansen G, Gielen-Haertwig H, Reinemer P, Schomburg D, Harrenga A, Niefind K. Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor. J Mol Biol 2011;409:681-91. [PMID: 21549129 DOI: 10.1016/j.jmb.2011.04.047] [Cited by in Crossref: 30] [Cited by in F6Publishing: 27] [Article Influence: 2.7] [Reference Citation Analysis]
60 Svenson J, Karstad R, Flaten GE, Brandsdal BO, Brandl M, Svendsen JS. Altered activity and physicochemical properties of short cationic antimicrobial peptides by incorporation of arginine analogues. Mol Pharm 2009;6:996-1005. [PMID: 19341291 DOI: 10.1021/mp900057k] [Cited by in Crossref: 34] [Cited by in F6Publishing: 33] [Article Influence: 2.6] [Reference Citation Analysis]
61 Kim TS, Hague AB, Lee TI, Lian B, Tegley CM, Wang X, Burgess TL, Qian YX, Ross S, Tagari P, Lin CH, Mayeda C, Dao J, Jordan S, Mohr C, Cheetham J, Viswanadhan V, Tasker AS. (4-Piperidinylphenyl)aminoethyl amides as a novel class of non-covalent cathepsin K inhibitors. Bioorg Med Chem Lett 2004;14:87-90. [PMID: 14684304 DOI: 10.1016/j.bmcl.2003.10.009] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.4] [Reference Citation Analysis]
62 Santos ALSD. Protease expression by microorganisms and its relevance to crucial physiological/pathological events. World J Biol Chem 2011; 2(3): 48-58 [PMID: 21537490 DOI: 10.4331/wjbc.v2.i3.48] [Cited by in CrossRef: 19] [Cited by in F6Publishing: 13] [Article Influence: 1.7] [Reference Citation Analysis]
63 Mane YD, Sarnikar YP, Surwase SM, Biradar DO, Gorepatil PB, Shinde VS, Khade BC. Design, synthesis, and antimicrobial activity of novel 5-substituted indole-2-carboxamide derivatives. Res Chem Intermed 2017;43:1253-75. [DOI: 10.1007/s11164-016-2696-3] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
64 Tavares FX, Deaton DN, Miller LR, Wright LL. Ketoamide-Based Inhibitors of Cysteine Protease, Cathepsin K:  P3 Modifications. J Med Chem 2004;47:5057-68. [DOI: 10.1021/jm040107n] [Cited by in Crossref: 13] [Cited by in F6Publishing: 8] [Article Influence: 0.7] [Reference Citation Analysis]
65 Harada N, Okajima K, Isobe H. Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats. Shock 2008;30:379-87. [PMID: 18323746 DOI: 10.1097/SHK.0b013e3181673e2c] [Cited by in Crossref: 9] [Cited by in F6Publishing: 2] [Article Influence: 0.6] [Reference Citation Analysis]
66 Morgan T, Ray NC, Parry DM. A Solid-Phase Route to N -Cyanoamides. Org Lett 2002;4:597-8. [DOI: 10.1021/ol0172020] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 0.4] [Reference Citation Analysis]
67 Vagnoni LM, Gronostaj M, Kerrigan JE. 6-acylamino-2-[(ethylsulfonyl)oxy]-1H-isoindole-1,3-diones mechanism-based inhibitors of human leukocyte elastase and cathepsin G: effect of chirality in the 6-acylamino substituent on inhibitory potency and selectivity. Bioorganic & Medicinal Chemistry 2001;9:637-45. [DOI: 10.1016/s0968-0896(00)00281-9] [Cited by in Crossref: 6] [Article Influence: 0.3] [Reference Citation Analysis]
68 Madala PK, Tyndall JDA, Nall T, Fairlie DP. Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites. Chem Rev 2010;110:PR1-PR31. [DOI: 10.1021/cr900368a] [Cited by in Crossref: 118] [Cited by in F6Publishing: 106] [Article Influence: 10.7] [Reference Citation Analysis]
69 Raghavan S, Yang Z, Mosley RT, Schleif WA, Gabryelski L, Olsen DB, Stahlhut M, Kuo LC, Emini EA, Chapman KT, Tata JR. Combinatorial library of indinavir analogues: replacement for the aminoindanol at P2′. Bioorganic & Medicinal Chemistry Letters 2002;12:2855-8. [DOI: 10.1016/s0960-894x(02)00632-7] [Cited by in Crossref: 12] [Article Influence: 0.6] [Reference Citation Analysis]
70 Schmidt F, Keller F, Vedrenne E, Aggarwal V. Stereocontrolled Synthesis of β-Amino Alcohols from Lithiated Aziridines and Boronic Esters. Angew Chem 2009;121:1169-72. [DOI: 10.1002/ange.200805272] [Cited by in Crossref: 10] [Article Influence: 0.8] [Reference Citation Analysis]
71 Pagán M, Solá RJ, Griebenow K. On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg. Biotechnol Bioeng 2009;103:77-84. [PMID: 19132746 DOI: 10.1002/bit.22221] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 1.0] [Reference Citation Analysis]
72 Fewer DP, Jokela J, Rouhiainen L, Wahlsten M, Koskenniemi K, Stal LJ, Sivonen K. The non-ribosomal assembly and frequent occurrence of the protease inhibitors spumigins in the bloom-forming cyanobacterium Nodularia spumigena. Molecular Microbiology 2009;73:924-37. [DOI: 10.1111/j.1365-2958.2009.06816.x] [Cited by in Crossref: 53] [Cited by in F6Publishing: 52] [Article Influence: 4.1] [Reference Citation Analysis]
73 Specker E, Böttcher J, Brass S, Heine A, Lilie H, Schoop A, Müller G, Griebenow N, Klebe G. Unexpected novel binding mode of pyrrolidine-based aspartyl protease inhibitors: design, synthesis and crystal structure in complex with HIV protease. ChemMedChem 2006;1:106-17. [PMID: 16892342 DOI: 10.1002/cmdc.200500008] [Cited by in Crossref: 22] [Cited by in F6Publishing: 21] [Article Influence: 1.4] [Reference Citation Analysis]
74 Kemnitzer W, Kuemmerle J, Jiang S, Sirisoma N, Kasibhatla S, Crogan-Grundy C, Tseng B, Drewe J, Cai SX. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions. Bioorg Med Chem Lett 2009;19:3481-4. [PMID: 19467598 DOI: 10.1016/j.bmcl.2009.05.012] [Cited by in Crossref: 30] [Cited by in F6Publishing: 24] [Article Influence: 2.3] [Reference Citation Analysis]
75 Lazareva NF, Lazarev IM. Drug design based on the carbon/silicon switch strategy. Russ Chem Bull 2015;64:1221-32. [DOI: 10.1007/s11172-015-1005-4] [Cited by in Crossref: 12] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
76 Benedetti F, Berti F, Dinon F, Nardin G, Norbedo S. Synthesis of a Val-Pro Diaminodiol Dipeptide Isostere by Epoxyamine Cyclization. Org Lett 2004;6:1017-9. [DOI: 10.1021/ol0499147] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
77 Per TS, Khan S, Asgher M, Bano B, Khan NA. Photosynthetic and growth responses of two mustard cultivars differing in phytocystatin activity under cadmium stress. Photosynt 2016;54:491-501. [DOI: 10.1007/s11099-016-0205-y] [Cited by in Crossref: 26] [Cited by in F6Publishing: 11] [Article Influence: 4.3] [Reference Citation Analysis]
78 Inglis SR, Zervosen A, Woon EC, Gerards T, Teller N, Fischer DS, Luxen A, Schofield CJ. Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors. J Med Chem 2009;52:6097-106. [PMID: 19731939 DOI: 10.1021/jm9009718] [Cited by in Crossref: 31] [Cited by in F6Publishing: 26] [Article Influence: 2.4] [Reference Citation Analysis]
79 Ersmark K, Del valle J, Hanessian S. Aeruginosine: Chemie und Biologie der Serinprotease-Inhibitoren. Angew Chem 2008;120:1220-42. [DOI: 10.1002/ange.200605219] [Cited by in Crossref: 28] [Cited by in F6Publishing: 21] [Article Influence: 2.0] [Reference Citation Analysis]
80 Gasbarri C, Angelini G, Fontana A, De Maria P, Siani G, Giannicchi I, Cort AD. Kinetics of demetallation of a zinc–salophen complex into liposomes. Biochimica et Biophysica Acta (BBA) - Biomembranes 2012;1818:747-52. [DOI: 10.1016/j.bbamem.2011.10.014] [Cited by in Crossref: 13] [Cited by in F6Publishing: 9] [Article Influence: 1.3] [Reference Citation Analysis]
81 Curnow P, Bessette PH, Kisailus D, Murr MM, Daugherty PS, Morse DE. Enzymatic Synthesis of Layered Titanium Phosphates at Low Temperature and Neutral pH by Cell-Surface Display of Silicatein-α. J Am Chem Soc 2005;127:15749-55. [DOI: 10.1021/ja054307f] [Cited by in Crossref: 65] [Cited by in F6Publishing: 52] [Article Influence: 3.8] [Reference Citation Analysis]
82 Verissimo E, Berry N, Gibbons P, Cristiano MLS, Rosenthal PJ, Gut J, Ward SA, O’neill PM. Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors. Bioorganic & Medicinal Chemistry Letters 2008;18:4210-4. [DOI: 10.1016/j.bmcl.2008.05.068] [Cited by in Crossref: 44] [Cited by in F6Publishing: 31] [Article Influence: 3.1] [Reference Citation Analysis]
83 Schaal W, Karlsson A, Ahlsén G, Lindberg J, Andersson HO, Danielson UH, Classon B, Unge T, Samuelsson B, Hultén J, Hallberg A, Karlén A. Synthesis and Comparative Molecular Field Analysis (CoMFA) of Symmetric and Nonsymmetric Cyclic Sulfamide HIV-1 Protease Inhibitors. J Med Chem 2001;44:155-69. [DOI: 10.1021/jm001024j] [Cited by in Crossref: 85] [Cited by in F6Publishing: 68] [Article Influence: 3.9] [Reference Citation Analysis]
84 Southan C. Assessing the protease and protease inhibitor content of the human genome. J Peptide Sci 2000;6:453-8. [DOI: 10.1002/1099-1387(200009)6:9<453::aid-psc284>3.0.co;2-z] [Cited by in Crossref: 19] [Cited by in F6Publishing: 4] [Article Influence: 0.9] [Reference Citation Analysis]
85 Das BC, Mahalingam SM, Das S, Hosmane NS, Evans T. Synthesis of Pinacolylboronate-Substituted Stilbenes and their application to the synthesis of boron capped polyenes. Journal of Organometallic Chemistry 2015;798:51-9. [DOI: 10.1016/j.jorganchem.2015.08.007] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
86 Liu T, Zhu N, Zhong C, Zhu Y, Gou S, Chang L, Bao H, Liu H, Zhang Y, Ni J. Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin. Eur J Pharm Sci 2020;152:105453. [PMID: 32649983 DOI: 10.1016/j.ejps.2020.105453] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
87 Pinto DJP, Smallheer JM, Cheney DL, Knabb RM, Wexler RR. Factor Xa Inhibitors: Next-Generation Antithrombotic Agents. J Med Chem 2010;53:6243-74. [DOI: 10.1021/jm100146h] [Cited by in Crossref: 98] [Cited by in F6Publishing: 80] [Article Influence: 8.2] [Reference Citation Analysis]
88 Wei L, Gan X, Zhong J, Alliston KR, Groutas WC. Noncovalent inhibitors of human leukocyte elastase based on the 4-imidazolidinone scaffold. Bioorganic & Medicinal Chemistry 2003;11:5149-53. [DOI: 10.1016/j.bmc.2003.08.030] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
89 Brewer M, Oost T, Sukonpan C, Pereckas M, Rich DH. Sequencing Hydroxyethylamine-Containing Peptides via Edman Degradation. Org Lett 2002;4:3469-72. [DOI: 10.1021/ol026590i] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
90 Morcelle SR, Cánepa AS, Padró JM, Llerena-suster CR, Clapés P. Syntheses of dipeptide alcohols and dipeptide aldehyde precursors catalyzed by plant cysteine peptidases. Journal of Molecular Catalysis B: Enzymatic 2013;89:130-6. [DOI: 10.1016/j.molcatb.2012.12.004] [Cited by in Crossref: 2] [Article Influence: 0.2] [Reference Citation Analysis]
91 Ivanovich RA, Polat DE, Beauchemin AM. Oxygen-Substituted Isocyanates: Blocked (Masked) Isocyanates Enable Controlled Reactivity. Adv Synth Catal 2017;359:4289-93. [DOI: 10.1002/adsc.201701046] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.2] [Reference Citation Analysis]
92 Mizuno H, Fujimoto Z, Atoda H, Morita T. Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X. Proc Natl Acad Sci U S A 2001;98:7230-4. [PMID: 11404471 DOI: 10.1073/pnas.131179698] [Cited by in Crossref: 106] [Cited by in F6Publishing: 91] [Article Influence: 5.0] [Reference Citation Analysis]
93 Chappell KJ, Stoermer MJ, Fairlie DP, Young PR. Insights to Substrate Binding and Processing by West Nile Virus NS3 Protease through Combined Modeling, Protease Mutagenesis, and Kinetic Studies. Journal of Biological Chemistry 2006;281:38448-58. [DOI: 10.1074/jbc.m607641200] [Cited by in Crossref: 74] [Cited by in F6Publishing: 21] [Article Influence: 4.6] [Reference Citation Analysis]
94 Brzozowski Z, Saczewski F, Gdaniec M. Synthesis, structural characterization and in vitro antitumor activity of novel 6-chloro-1,1-dioxo-1,4,2-benzodithiazie derivatives. Bioorg Med Chem 2003;11:3673-81. [PMID: 12901913 DOI: 10.1016/s0968-0896(03)00345-6] [Cited by in Crossref: 28] [Cited by in F6Publishing: 3] [Article Influence: 1.6] [Reference Citation Analysis]
95 Marcy H, Carol A. F. A Method to Assay Inhibitors of Lipopolysaccharide Synthesis. In: Champney WS, editor. New Antibiotic Targets. Totowa: Humana Press; 2008. pp. 143-54. [DOI: 10.1007/978-1-59745-246-5_12] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
96 Cai SX, Guan L, Jia S, Wang Y, Yang W, Tseng B, Drewe J. Dipeptidyl aspartyl fluoromethylketones as potent caspase inhibitors: SAR of the N-protecting group. Bioorganic & Medicinal Chemistry Letters 2004;14:5295-300. [DOI: 10.1016/j.bmcl.2004.08.027] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 1.1] [Reference Citation Analysis]
97 Pesenti C, Arnone A, Arosio P, Frigerio M, Meille SV, Panzeri W, Viani F, Zanda M. Stereocontrolled synthesis of hydroxyethylamine isosteres via chiral sulfoxide chemistry. Tetrahedron Letters 2004;45:5125-9. [DOI: 10.1016/j.tetlet.2004.04.160] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
98 Kim JH, Cho YH, Park SM, Lee KE, Lee JJ, Lee BC, Pyo HB, Song KS, Park HD, Yun YP. Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves of Zostera marina L. Arch Pharm Res 2004;27:177-83. [PMID: 15022719 DOI: 10.1007/BF02980103] [Cited by in Crossref: 41] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
99 Nakamura H, Kuroda H, Saito H, Suzuki R, Yamori T, Maruyama K, Haga T. Synthesis and biological evaluation of boronic acid containing cis-stilbenes as apoptotic tubulin polymerization inhibitors. ChemMedChem 2006;1:729-40. [PMID: 16902927 DOI: 10.1002/cmdc.200600068] [Cited by in Crossref: 31] [Cited by in F6Publishing: 24] [Article Influence: 1.9] [Reference Citation Analysis]
100 Al-tel TH, Semreen MH, Al-qawasmeh RA, Schmidt MF, El-awadi R, Ardah M, Zaarour R, Rao SN, El-agnaf O. Design, Synthesis, and Qualitative Structure–Activity Evaluations of Novel β-Secretase Inhibitors as Potential Alzheimer’s Drug Leads. J Med Chem 2011;54:8373-85. [DOI: 10.1021/jm201181f] [Cited by in Crossref: 33] [Cited by in F6Publishing: 29] [Article Influence: 3.0] [Reference Citation Analysis]
101 Organ MG, Buon C, Decicco CP, Combs AP. A Concise Synthesis of Silanediol-Based Transition-State Isostere Inhibitors of Proteases. Org Lett 2002;4:2683-5. [DOI: 10.1021/ol026195s] [Cited by in Crossref: 21] [Cited by in F6Publishing: 14] [Article Influence: 1.1] [Reference Citation Analysis]
102 Volonterio A, Bravo P, Corradi E, Fronza G, Meille SV, Vergani B, Zanda M. Unusual nonchelation controlled allylation of a N -monoprotected α-amino aldehyde: stereoselective entry to nonracemic trifluoromethyl dipeptide isosteres. Journal of Fluorine Chemistry 2001;108:245-52. [DOI: 10.1016/s0022-1139(01)00363-3] [Cited by in Crossref: 6] [Article Influence: 0.3] [Reference Citation Analysis]
103 Ganta KK, Chaubey B. Mitochondrial dysfunctions in HIV infection and antiviral drug treatment. Expert Opin Drug Metab Toxicol 2019;15:1043-52. [PMID: 31715109 DOI: 10.1080/17425255.2019.1692814] [Reference Citation Analysis]
104 Ding X, Yang K. Enzymatic Deposition of Silver Particles for Detecting Protease Activity. Part Part Syst Charact 2014;31:1300-6. [DOI: 10.1002/ppsc.201400107] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
105 Pascual I, Lopéz A, Gómez H, Chappé M, Saroyán A, González Y, Cisneros M, Charli JL, Chávez MDLA. Screening of inhibitors of porcine dipeptidyl peptidase IV activity in aqueous extracts from marine organisms. Enzyme and Microbial Technology 2007;40:414-9. [DOI: 10.1016/j.enzmictec.2006.07.012] [Cited by in Crossref: 20] [Cited by in F6Publishing: 10] [Article Influence: 1.3] [Reference Citation Analysis]
106 Yuan Z, Trias J, White RJ. Deformylase as a novel antibacterial target. Drug Discovery Today 2001;6:954-61. [DOI: 10.1016/s1359-6446(01)01925-0] [Cited by in Crossref: 99] [Cited by in F6Publishing: 18] [Article Influence: 4.7] [Reference Citation Analysis]
107 Dugave C, Demange L. Cis−Trans Isomerization of Organic Molecules and Biomolecules:  Implications and Applications. Chem Rev 2003;103:2475-532. [DOI: 10.1021/cr0104375] [Cited by in Crossref: 730] [Cited by in F6Publishing: 541] [Article Influence: 38.4] [Reference Citation Analysis]
108 Lai Y, Li B, Liu W, Wang G, Du C, Ombati R, Lai R, Long C, Li H. Purification and Characterization of a Novel Kazal-Type Trypsin Inhibitor from the Leech of Hirudinaria manillensis. Toxins (Basel) 2016;8:E229. [PMID: 27455325 DOI: 10.3390/toxins8080229] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 0.7] [Reference Citation Analysis]
109 Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. High-throughput screening assays for the identification of chemical probes. Nat Chem Biol 2007;3:466-79. [PMID: 17637779 DOI: 10.1038/nchembio.2007.17] [Cited by in Crossref: 426] [Cited by in F6Publishing: 390] [Article Influence: 28.4] [Reference Citation Analysis]
110 Bonini C, Chiummiento L, Bonis MD, Funicello M, Lupattelli P, Suanno G, Berti F, Campaner P. Synthesis, biological activity and modelling studies of two novel anti HIV PR inhibitors with a thiophene containing hydroxyethylamino core. Tetrahedron 2005;61:6580-9. [DOI: 10.1016/j.tet.2005.04.048] [Cited by in Crossref: 56] [Cited by in F6Publishing: 25] [Article Influence: 3.3] [Reference Citation Analysis]
111 Gu L, Liu F, Li X, Gao B, Yang B. Synthesis of Novel Bis-statine-based Peptide Containing Ferrocenyl Moiety. Synthetic Communications 2009;40:242-6. [DOI: 10.1080/00397910902964833] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
112 Donev R, Kolev M, Millet B, Thome J. Neuronal death in Alzheimer's disease and therapeutic opportunities. J Cell Mol Med 2009;13:4329-48. [PMID: 19725918 DOI: 10.1111/j.1582-4934.2009.00889.x] [Cited by in Crossref: 59] [Cited by in F6Publishing: 51] [Article Influence: 4.5] [Reference Citation Analysis]
113 Kim C, Lee D, Lee C, Ahn I. A dityrosine-based substrate for a protease assay: Application for the selective assessment of papain and chymopapain activity. Analytica Chimica Acta 2012;723:101-7. [DOI: 10.1016/j.aca.2012.02.038] [Cited by in Crossref: 17] [Cited by in F6Publishing: 13] [Article Influence: 1.7] [Reference Citation Analysis]
114 Sieburth SM, Chen C. Silanediol Protease Inhibitors: From Conception to Validation. Eur J Org Chem 2006;2006:311-22. [DOI: 10.1002/ejoc.200500508] [Cited by in Crossref: 119] [Cited by in F6Publishing: 83] [Article Influence: 7.4] [Reference Citation Analysis]
115 Harris BC, Korampally V, Weilbaecher C, Polo-parada L, Grant S, Gangopadhyay S. Protease biosensing on novel high surface area organosilicate nanoporous films. Sensors and Actuators B: Chemical 2013;176:351-9. [DOI: 10.1016/j.snb.2012.08.082] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.8] [Reference Citation Analysis]
116 Larhed M, Wannberg J, Hallberg A. Controlled Microwave Heating as an Enabling Technology: Expedient Synthesis of Protease Inhibitors in Perspective. QSAR Comb Sci 2007;26:51-68. [DOI: 10.1002/qsar.200620028] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
117 Schumann NC, Bruning J, Marshall AC, Abell AD. The role of N-terminal heterocycles in hydrogen bonding to α-chymotrypsin. Bioorg Med Chem Lett 2019;29:396-9. [PMID: 30579793 DOI: 10.1016/j.bmcl.2018.12.032] [Reference Citation Analysis]
118 Mak CC, Le V, Lin Y, Elder JH, Wong C. Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3′ residue. Bioorganic & Medicinal Chemistry Letters 2001;11:219-22. [DOI: 10.1016/s0960-894x(00)00641-7] [Cited by in Crossref: 14] [Cited by in F6Publishing: 3] [Article Influence: 0.7] [Reference Citation Analysis]
119 Friedel M, Lindel T. Synthesis of l-aminohomohistidine (l-Ahh). Tetrahedron Letters 2004;45:2779-81. [DOI: 10.1016/j.tetlet.2004.02.027] [Cited by in Crossref: 5] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
120 Garske AL, Peters U, Cortesi AT, Perez JL, Shokat KM. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A 2011;108:15046-52. [PMID: 21852571 DOI: 10.1073/pnas.1111239108] [Cited by in Crossref: 62] [Cited by in F6Publishing: 56] [Article Influence: 5.6] [Reference Citation Analysis]
121 Thompson LA, Tebben AJ. Chapter 24. Pharmacokinetics and design of aspartyl protease inhibitors. Elsevier; 2001. pp. 247-56. [DOI: 10.1016/s0065-7743(01)36064-5] [Cited by in Crossref: 5] [Article Influence: 0.2] [Reference Citation Analysis]
122 Chung J, Bae Y, Na B, Kong Y. Cysteine protease inhibitors as potential antiparasitic agents. Expert Opinion on Therapeutic Patents 2005;15:995-1007. [DOI: 10.1517/13543776.15.8.995] [Cited by in Crossref: 13] [Cited by in F6Publishing: 8] [Article Influence: 0.8] [Reference Citation Analysis]
123 Jiang C, Bao R, Chen Y. Expression, purification, crystallization and preliminary X-ray diffraction analysis of Sagittaria sagittifolia arrowhead protease inhibitor API-A in complex with bovine trypsin. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008;64:1060-2. [PMID: 18997342 DOI: 10.1107/S1744309108032454] [Cited by in Crossref: 3] [Article Influence: 0.2] [Reference Citation Analysis]
124 Xue F, Seto CT. Selective Inhibitors of the Serine Protease Plasmin:  Probing the S3 and S3‘ Subsites Using a Combinatorial Library. J Med Chem 2005;48:6908-17. [DOI: 10.1021/jm050488k] [Cited by in Crossref: 18] [Cited by in F6Publishing: 12] [Article Influence: 1.1] [Reference Citation Analysis]
125 Nielsen L, Skrydstrup T. Sequential C−Si Bond Formations from Diphenylsilane: Application to Silanediol Peptide Isostere Precursors. J Am Chem Soc 2008;130:13145-51. [DOI: 10.1021/ja804720p] [Cited by in Crossref: 72] [Cited by in F6Publishing: 51] [Article Influence: 5.1] [Reference Citation Analysis]
126 Sheppeck Ii JE, Kar H, Gosink L, Wheatley JB, Gjerstad E, Loftus SM, Zubiria AR, Janc JW. Synthesis of a statistically exhaustive fluorescent peptide substrate library for profiling protease specificity. Bioorganic & Medicinal Chemistry Letters 2000;10:2639-42. [DOI: 10.1016/s0960-894x(00)00545-x] [Cited by in Crossref: 26] [Cited by in F6Publishing: 3] [Article Influence: 1.2] [Reference Citation Analysis]
127 Nilsson M, Hämäläinen M, Ivarsson M, Gottfries J, Xue Y, Hansson S, Isaksson R, Fex T. Compounds binding to the S2-S3 pockets of thrombin. J Med Chem 2009;52:2708-15. [PMID: 19371038 DOI: 10.1021/jm8011849] [Cited by in Crossref: 27] [Cited by in F6Publishing: 25] [Article Influence: 2.1] [Reference Citation Analysis]
128 Mulchande J, Martins L, Moreira R, Archer M, Oliveira TF, Iley J. The efficiency of C-4 substituents in activating the β-lactam scaffold towards serine proteases and hydroxide ion. Org Biomol Chem 2007;5:2617. [DOI: 10.1039/b706622h] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
129 Steindl TM, Schuster D, Laggner C, Chuang K, Hoffmann RD, Langer T. Parallel screening and activity profiling with HIV protease inhibitor pharmacophore models. J Chem Inf Model 2007;47:563-71. [PMID: 17381173 DOI: 10.1021/ci600321m] [Cited by in Crossref: 39] [Cited by in F6Publishing: 32] [Article Influence: 2.6] [Reference Citation Analysis]
130 O'Brien SE, Brown DG, Mills JE, Phillips C, Morris G. Computational tools for the analysis and visualization of multiple protein-ligand complexes. J Mol Graph Model 2005;24:186-94. [PMID: 16169759 DOI: 10.1016/j.jmgm.2005.08.003] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
131 Zhang Q, Li W, Chen J, Wang F, Wang Y, Chen Y, Yu C. An ultrasensitive chemiluminescence turn-on assay for protease and inhibitor screening with a natural substrate. Chem Commun 2013;49:3137. [DOI: 10.1039/c3cc40906f] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 2.9] [Reference Citation Analysis]
132 Amélia Santos M, Marques S, Gil M, Tegoni M, Scozzafava A, Supuran CT. Protease Inhibitors: Synthesis of Bacterial Collagenase and Matrix Metalloproteinase Inhibitors Incorporating Succinyl Hydroxamate and Iminodiacetic Acid Hydroxamate Moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 2008;18:233-42. [DOI: 10.1080/1475636031000081134] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 0.9] [Reference Citation Analysis]
133 Maignan S, Guilloteau J, Pouzieux S, Choi-sledeski YM, Becker MR, Klein SI, Ewing WR, Pauls HW, Spada AP, Mikol V. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors. J Med Chem 2000;43:3226-32. [DOI: 10.1021/jm000940u] [Cited by in Crossref: 111] [Cited by in F6Publishing: 101] [Article Influence: 5.0] [Reference Citation Analysis]
134 Mikkelsen LM, Jensen CM, Høj B, Blakskjær P, Skrydstrup T. Further studies in the acyl-type radical additions promoted by SmI 2 : mechanistic implications and stereoselective reduction of the keto-functionality. Tetrahedron 2003;59:10541-9. [DOI: 10.1016/j.tet.2003.07.016] [Cited by in Crossref: 20] [Cited by in F6Publishing: 15] [Article Influence: 1.1] [Reference Citation Analysis]
135 Wess G, Urmann M, Sickenberger B. Medizinische Chemie: Herausforderungen und Chancen. Angew Chem 2001;113:3443-53. [DOI: 10.1002/1521-3757(20010917)113:18<3443::aid-ange3443>3.0.co;2-s] [Cited by in Crossref: 15] [Article Influence: 0.7] [Reference Citation Analysis]
136 Augé F, Hornebeck W, Laronze J. A novel strategy for designing specific gelatinase A inhibitors: potential use to control tumor progression. Critical Reviews in Oncology/Hematology 2004;49:277-82. [DOI: 10.1016/j.critrevonc.2003.10.006] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 0.7] [Reference Citation Analysis]
137 Bimoussa A, Oubella A, El Mansouri A, Fawzi M, Laamari Y, Auhmani A, Itto MYA, Morjani H, Auhmani A. Synthesis and Biological Evaluation of Novel Thiazole Analogs with Both Anti‐Proliferative and Mechanistic Analyses and Molecular Docking Studies. ChemistrySelect 2022;7. [DOI: 10.1002/slct.202104270] [Reference Citation Analysis]
138 Dener JM, Rice KD, Newcomb WS, Wang VR, Young WB, Gangloff AR, Kuo EY, Cregar L, Putnam D, Wong M. Dibasic Inhibitors of Human Mast Cell Tryptase. Part 3: Identification of a Series of Potent and Selective Inhibitors Containing the Benzamidine Functionality. Bioorganic & Medicinal Chemistry Letters 2001;11:1629-33. [DOI: 10.1016/s0960-894x(01)00254-2] [Cited by in Crossref: 14] [Article Influence: 0.7] [Reference Citation Analysis]
139 Molteni M, Bellucci MC, Bigotti S, Mazzini S, Volonterio A, Zanda M. Ψ[CH(CF3)NH]Gly-peptides: synthesis and conformation analysis. Org Biomol Chem 2009;7:2286. [DOI: 10.1039/b901718f] [Cited by in Crossref: 36] [Cited by in F6Publishing: 26] [Article Influence: 2.8] [Reference Citation Analysis]
140 Shankar R, Kolandaivel P, Senthilkumar K. Reaction mechanism of cysteine proteases model compound HSH with diketone inhibitor PhCOCOCH 3− n X n , (X = F, Cl, n = 0, 1, 2): Reaction Mechanism of Cysteine Proteases Model Compound HSH. Int J Quantum Chem 2010;110:1660-74. [DOI: 10.1002/qua.22332] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
141 Shi S, Zhu S, Gerritz SW, Rachwal B, Ruan Z, Hutchins R, Kakarla R, Sofia MJ, Sutton J, Cheney D. Solid-phase synthesis of a library based on biphenyl-containing trypsin-like serine protease inhibitors. Bioorg Med Chem Lett 2009;19:6477-80. [PMID: 19804972 DOI: 10.1016/j.bmcl.2009.08.100] [Cited by in Crossref: 5] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
142 Maly DJ, Huang L, Ellman JA. Combinatorial Strategies for Targeting Protein Families: Application to the Proteases. ChemBioChem 2002;3:16-37. [DOI: 10.1002/1439-7633(20020104)3:1<16::aid-cbic16>3.0.co;2-z] [Cited by in Crossref: 52] [Cited by in F6Publishing: 6] [Article Influence: 2.6] [Reference Citation Analysis]
143 Karstad R, Isaksen G, Brandsdal B, Svendsen JS, Svenson J. Unnatural Amino Acid Side Chains as S1, S1′, and S2′ Probes Yield Cationic Antimicrobial Peptides with Stability toward Chymotryptic Degradation. J Med Chem 2010;53:5558-66. [DOI: 10.1021/jm1006337] [Cited by in Crossref: 27] [Cited by in F6Publishing: 24] [Article Influence: 2.3] [Reference Citation Analysis]
144 Hailu GS, Robaa D, Forgione M, Sippl W, Rotili D, Mai A. Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives. J Med Chem 2017;60:4780-804. [DOI: 10.1021/acs.jmedchem.6b01595] [Cited by in Crossref: 54] [Cited by in F6Publishing: 47] [Article Influence: 10.8] [Reference Citation Analysis]
145 Tsang W, Ahmed N, Hemming K, Page MI. Reactivity and selectivity in the inhibition of elastase by 3-oxo-β-sultams and in their hydrolysis. Org Biomol Chem 2007;5:3993. [DOI: 10.1039/b713899g] [Cited by in Crossref: 20] [Cited by in F6Publishing: 13] [Article Influence: 1.3] [Reference Citation Analysis]
146 Rudzinska-radecka M, Frolova AS, Balakireva AV, Gorokhovets NV, Pokrovsky VS, Sokolova DV, Korolev DO, Potoldykova NV, Vinarov AZ, Parodi A, Zamyatnin AA. In Silico, In Vitro, and Clinical Investigations of Cathepsin B and Stefin A mRNA Expression and a Correlation Analysis in Kidney Cancer. Cells 2022;11:1455. [DOI: 10.3390/cells11091455] [Reference Citation Analysis]
147 Schmidt B. Aspartic proteases involved in Alzheimer's disease. Chembiochem 2003;4:366-78. [PMID: 12740808 DOI: 10.1002/cbic.200200532] [Cited by in Crossref: 26] [Cited by in F6Publishing: 24] [Article Influence: 1.4] [Reference Citation Analysis]
148 García-Horsman JA, Männistö PT, Venäläinen JI. On the role of prolyl oligopeptidase in health and disease. Neuropeptides 2007;41:1-24. [PMID: 17196652 DOI: 10.1016/j.npep.2006.10.004] [Cited by in Crossref: 154] [Cited by in F6Publishing: 145] [Article Influence: 9.6] [Reference Citation Analysis]
149 Langhammer S. Rationale for the design of an oncology trial using a generic targeted therapy multi‑drug regimen for NSCLC patients without treatment options (Review). Oncol Rep 2013;30:1535-41. [PMID: 23877481 DOI: 10.3892/or.2013.2631] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
150 James KE, Asgian JL, Li ZZ, Ekici ÖD, Rubin JR, Mikolajczyk J, Salvesen GS, Powers JC. Design, Synthesis, and Evaluation of Aza-Peptide Epoxides as Selective and Potent Inhibitors of Caspases-1, -3, -6, and -8. J Med Chem 2004;47:1553-74. [DOI: 10.1021/jm0305016] [Cited by in Crossref: 40] [Cited by in F6Publishing: 42] [Article Influence: 2.2] [Reference Citation Analysis]
151 Castro E, Martinez ZS, Seong CS, Cabrera-Espinoza A, Ruiz M, Hernandez Garcia A, Valdez F, Llano M, Echegoyen L. Characterization of New Cationic N,N-Dimethyl[70]fulleropyrrolidinium Iodide Derivatives as Potent HIV-1 Maturation Inhibitors. J Med Chem 2016;59:10963-73. [PMID: 28002960 DOI: 10.1021/acs.jmedchem.6b00994] [Cited by in Crossref: 18] [Cited by in F6Publishing: 14] [Article Influence: 3.0] [Reference Citation Analysis]
152 Sergeev ME, Voyushina TL, Sergeeva OA, Belozerskaya GG. Efficient enzyme-catalyzed synthesis of peptide secondary amides for use as serine proteinase inhibitors. Journal of Molecular Catalysis B: Enzymatic 2012;80:58-66. [DOI: 10.1016/j.molcatb.2012.04.019] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
153 Sheehan SM, Mest H, Watson BM, Klimkowski VJ, Timm DE, Cauvin A, Parsons SH, Shi Q, Canada EJ, Wiley MR, Ruehter G, Evers B, Petersen S, Blaszczak LC, Pulley SR, Margolis BJ, Wishart GN, Renson B, Hankotius D, Mohr M, Zechel J, Michael Kalbfleisch J, Dingess-hammond EA, Boelke A, Weichert AG. Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site. Bioorganic & Medicinal Chemistry Letters 2007;17:1765-8. [DOI: 10.1016/j.bmcl.2006.12.074] [Cited by in Crossref: 14] [Cited by in F6Publishing: 10] [Article Influence: 0.9] [Reference Citation Analysis]
154 Bendre AD, Ramasamy S, Suresh CG. Analysis of Kunitz inhibitors from plants for comprehensive structural and functional insights. Int J Biol Macromol 2018;113:933-43. [PMID: 29499268 DOI: 10.1016/j.ijbiomac.2018.02.148] [Cited by in Crossref: 25] [Cited by in F6Publishing: 20] [Article Influence: 6.3] [Reference Citation Analysis]
155 Piergies N, Proniewicz E, Kudelski A, Rydzewska A, Kim Y, Andrzejak M, Proniewicz LM. Fourier Transform Infrared and Raman and Surface-Enhanced Raman Spectroscopy Studies of a Novel Group of Boron Analogues of Aminophosphonic Acids. J Phys Chem A 2012;116:10004-14. [DOI: 10.1021/jp307064p] [Cited by in Crossref: 16] [Cited by in F6Publishing: 8] [Article Influence: 1.6] [Reference Citation Analysis]
156 El Mansouri A, Oubella A, Maatallah M, Aititto MY, Zahouily M, Morjani H, Lazrek HB. Design, synthesis, biological evaluation and molecular docking of new uracil analogs-1,2,4-oxadiazole hybrids as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters 2020;30:127438. [DOI: 10.1016/j.bmcl.2020.127438] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 4.5] [Reference Citation Analysis]
157 Kumar S, Pearson AL, Pratt RF. Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors. Bioorg Med Chem 2001;9:2035-44. [PMID: 11504640 DOI: 10.1016/s0968-0896(01)00107-9] [Cited by in Crossref: 18] [Cited by in F6Publishing: 3] [Article Influence: 0.9] [Reference Citation Analysis]
158 Temperini C, Innocenti A, Scozzafava A, Supuran CT. N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors. Bioorg Med Chem Lett 2006;16:4316-20. [PMID: 16759856 DOI: 10.1016/j.bmcl.2006.05.068] [Cited by in Crossref: 28] [Cited by in F6Publishing: 26] [Article Influence: 1.8] [Reference Citation Analysis]
159 Scozzafava A, Supuran CT. Protease inhibitors: Synthesis of matrix metalloproteinase and bacterial collagenase inhibitors incorporating 5-amino-2-mercapto-1,3,4-thiadiazole zinc binding functions. Bioorganic & Medicinal Chemistry Letters 2002;12:2667-72. [DOI: 10.1016/s0960-894x(02)00564-4] [Cited by in Crossref: 21] [Cited by in F6Publishing: 6] [Article Influence: 1.1] [Reference Citation Analysis]
160 Campestre C, Agamennone M, Tortorella P, Preziuso S, Biasone A, Gavuzzo E, Pochetti G, Mazza F, Hiller O, Tschesche H, Consalvi V, Gallina C. N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8. Bioorg Med Chem Lett 2006;16:20-4. [PMID: 16242329 DOI: 10.1016/j.bmcl.2005.09.057] [Cited by in Crossref: 39] [Cited by in F6Publishing: 37] [Article Influence: 2.3] [Reference Citation Analysis]
161 Schmidt F, Keller F, Vedrenne E, Aggarwal VK. Stereocontrolled synthesis of beta-amino alcohols from lithiated aziridines and boronic esters. Angew Chem Int Ed Engl 2009;48:1149-52. [PMID: 19115354 DOI: 10.1002/anie.200805272] [Cited by in Crossref: 55] [Cited by in F6Publishing: 33] [Article Influence: 4.2] [Reference Citation Analysis]
162 Calvaresi M, Zerbetto F. In Silico Carborane Docking to Proteins and Potential Drug Targets. J Chem Inf Model 2011;51:1882-96. [DOI: 10.1021/ci200216z] [Cited by in Crossref: 31] [Cited by in F6Publishing: 22] [Article Influence: 2.8] [Reference Citation Analysis]
163 Dang L, Van Damme EJM. Toxic proteins in plants. Phytochemistry 2015;117:51-64. [PMID: 26057229 DOI: 10.1016/j.phytochem.2015.05.020] [Cited by in Crossref: 59] [Cited by in F6Publishing: 39] [Article Influence: 8.4] [Reference Citation Analysis]
164 Kazakova O, Röschenthaler G. Pentafluoroethyl Lithium: Reactions with Carbonyl Compounds and Epoxides. In: Roesky HW, editor. Efficient Preparations of Fluorine Compounds. Hoboken: John Wiley & Sons, Inc.; 2012. pp. 205-9. [DOI: 10.1002/9781118409466.ch28] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
165 Coats SJ, Schulz MJ, Hlasta DJ. Method for the Parallel Preparation of the Aspartic Protease Isostere:  Hydroxyethylamino Amides. J Comb Chem 2004;6:688-91. [DOI: 10.1021/cc049911l] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
166 Sun S, Jia Q, Zhang Z. Applications of amide isosteres in medicinal chemistry. Bioorg Med Chem Lett 2019;29:2535-50. [PMID: 31377035 DOI: 10.1016/j.bmcl.2019.07.033] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 5.0] [Reference Citation Analysis]
167 Bromfield KM, Quinsey NS, Duggan PJ, Pike RN. Approaches to selective peptidic inhibitors of factor Xa. Chem Biol Drug Des 2006;68:11-9. [PMID: 16923021 DOI: 10.1111/j.1747-0285.2006.00404.x] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
168 Perni RB, Kwong AD. 5 Inhibitors of Hepatitis C Virus NS3•4A Protease: An Overdue Line of Therapy. Elsevier; 2002. pp. 215-55. [DOI: 10.1016/s0079-6468(08)70072-9] [Cited by in Crossref: 17] [Cited by in F6Publishing: 4] [Article Influence: 0.9] [Reference Citation Analysis]
169 St Hilaire PM, Alves LC, Herrera F, Renil M, Sanderson SJ, Mottram JC, Coombs GH, Juliano MA, Juliano L, Arevalo J, Meldal M. Solid-phase library synthesis, screening, and selection of tight-binding reduced peptide bond inhibitors of a recombinant Leishmania mexicana cysteine protease B. J Med Chem 2002;45:1971-82. [PMID: 11985465 DOI: 10.1021/jm0110901] [Cited by in Crossref: 31] [Cited by in F6Publishing: 27] [Article Influence: 1.6] [Reference Citation Analysis]
170 Altmann E, Cowan-jacob SW, Missbach M. Novel Purine Nitrile Derived Inhibitors of the Cysteine Protease Cathepsin K. J Med Chem 2004;47:5833-6. [DOI: 10.1021/jm0493111] [Cited by in Crossref: 57] [Cited by in F6Publishing: 48] [Article Influence: 3.2] [Reference Citation Analysis]
171 El Mansouri AE, Oubella A, Mehdi A, AitItto MY, Zahouily M, Morjani H, Lazrek HB. Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents. Bioorg Chem 2021;108:104558. [PMID: 33358270 DOI: 10.1016/j.bioorg.2020.104558] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
172 You CC, Agasti SS, De M, Knapp MJ, Rotello VM. Modulation of the catalytic behavior of alpha-chymotrypsin at monolayer-protected nanoparticle surfaces. J Am Chem Soc 2006;128:14612-8. [PMID: 17090046 DOI: 10.1021/ja064433z] [Cited by in Crossref: 104] [Cited by in F6Publishing: 87] [Article Influence: 6.9] [Reference Citation Analysis]
173 Covaleda G, Gallego P, Vendrell J, Georgiadis D, Lorenzo J, Dive V, Aviles FX, Reverter D, Devel L. Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J Med Chem 2019;62:1917-31. [PMID: 30688452 DOI: 10.1021/acs.jmedchem.8b01465] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
174 Epple R, Urbina HD, Russo R, Liu H, Mason D, Bursulaya B, Tumanut C, Li J, Harris JL. Bicyclic carbamates as inhibitors of papain-like cathepsin proteases. Bioorganic & Medicinal Chemistry Letters 2007;17:1254-9. [DOI: 10.1016/j.bmcl.2006.12.014] [Cited by in Crossref: 9] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
175 Njoroge FG, Chen KX, Shih NY, Piwinski JJ. Challenges in modern drug discovery: a case study of boceprevir, an HCV protease inhibitor for the treatment of hepatitis C virus infection. Acc Chem Res. 2008;41:50-59. [PMID: 18193821 DOI: 10.1021/ar700109k] [Cited by in Crossref: 176] [Cited by in F6Publishing: 148] [Article Influence: 12.6] [Reference Citation Analysis]
176 Godoy MS, Castro-Vazquez A, Vega IA. Endosymbiotic and host proteases in the digestive tract of the invasive snail Pomacea canaliculata: diversity, origin and characterization. PLoS One 2013;8:e66689. [PMID: 23818959 DOI: 10.1371/journal.pone.0066689] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 1.6] [Reference Citation Analysis]
177 Cheng A, Diller DJ, Dixon SL, Egan WJ, Lauri G, Merz KM Jr. Computation of the physio-chemical properties and data mining of large molecular collections. J Comput Chem 2002;23:172-83. [PMID: 11913384 DOI: 10.1002/jcc.1164] [Cited by in Crossref: 37] [Cited by in F6Publishing: 31] [Article Influence: 1.9] [Reference Citation Analysis]
178 Abbenante G, Reid RC, Fairlie DP. 'Clean' or 'Dirty' – Just How Selective Do Drugs Need To Be? Aust J Chem 2008;61:654. [DOI: 10.1071/ch08186] [Cited by in Crossref: 9] [Article Influence: 0.6] [Reference Citation Analysis]
179 Jia Z, Liu Y, Ji X, Zheng Y, Li Z, Jiang S, Li H, Kong Y. DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa. Pharmaceuticals (Basel) 2021;14:966. [PMID: 34681191 DOI: 10.3390/ph14100966] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
180 Naqvi T, Lim A, Rouhani R, Singh R, Eglen RM. Galactosidase Enzyme Fragment Complementation as a High-Throughput Screening Protease Technology. J Biomol Screen 2004;9:398-408. [DOI: 10.1177/1087057104264040] [Cited by in Crossref: 29] [Cited by in F6Publishing: 24] [Article Influence: 4.8] [Reference Citation Analysis]
181 Collet BY, Nagashima T, Yu MS, Pohl NL. Fluorous-based Peptide Microarrays for Protease Screening. J Fluor Chem 2009;130:1042-8. [PMID: 20161483 DOI: 10.1016/j.jfluchem.2009.09.005] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 1.5] [Reference Citation Analysis]
182 Xu N, Li Y, Li H, Wu Y. A Continuous Fluorometric Assay for Trypsin Based on Melittin and the Noncovalent-binding-induced Pyrene Excimer. Chem Lett 2013;42:1528-30. [DOI: 10.1246/cl.130713] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
183 Groutas WC, Epp JB, Kuang R, Ruan S, Chong LS, Venkataraman R, Tu J, He S, Yu H, Fu Q, Li YH, Truong TM, Vu NT. 1,2,5-Thiadiazolidin-3-one 1,1 Dioxide: A Powerful Scaffold for Probing the S′ Subsites of (Chymo)trypsin-Like Serine Proteases. Archives of Biochemistry and Biophysics 2001;385:162-9. [DOI: 10.1006/abbi.2000.2139] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 0.9] [Reference Citation Analysis]
184 Sieburth SM. Silicon Mimics of Unstable Carbon. In: Schwarz J, editor. Atypical Elements in Drug Design. Cham: Springer International Publishing; 2016. pp. 61-85. [DOI: 10.1007/7355_2014_80] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
185 Dumez E, Snaith JS, Jackson RF, McElroy AB, Overington J, Wythes MJ, Withka JM, McLellan TJ. Synthesis of macrocyclic, potential protease inhibitors using a generic scaffold. J Org Chem 2002;67:4882-92. [PMID: 12098301 DOI: 10.1021/jo025615o] [Cited by in Crossref: 28] [Cited by in F6Publishing: 22] [Article Influence: 1.5] [Reference Citation Analysis]
186 Gopinath P, Ramalingam K, Muraleedharan KM, Karunagaran D. Benzisothiazolones arrest the cell cycle at the G2/M phase and induce apoptosis in HeLa cells. Med Chem Commun 2013;4:749. [DOI: 10.1039/c3md00034f] [Cited by in Crossref: 9] [Article Influence: 1.0] [Reference Citation Analysis]
187 Kontogiorgis CA, Hadjipavlou-litina D. Current trends in quantitative structure activity relationships on FXa inhibitors: Evaluation and comparative analysis. Med Res Rev 2004;24:687-747. [DOI: 10.1002/med.20006] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 0.7] [Reference Citation Analysis]
188 Acker MG, Auld DS. Considerations for the design and reporting of enzyme assays in high-throughput screening applications. Perspectives in Science 2014;1:56-73. [DOI: 10.1016/j.pisc.2013.12.001] [Cited by in Crossref: 122] [Cited by in F6Publishing: 72] [Article Influence: 15.3] [Reference Citation Analysis]
189 Jarho EM, Venäläinen JI, Huuskonen J, Christiaans JA, Garcia-Horsman JA, Forsberg MM, Järvinen T, Gynther J, Männistö PT, Wallén EA. A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors. J Med Chem 2004;47:5605-7. [PMID: 15509157 DOI: 10.1021/jm049503w] [Cited by in Crossref: 52] [Cited by in F6Publishing: 50] [Article Influence: 2.9] [Reference Citation Analysis]
190 Righi G, Ciambrone S, Bonini C, Campaner P. Stereocontrolled synthesis and biological activity of two diastereoisomers of the potent HIV-1 protease inhibitor saquinavir. Bioorganic & Medicinal Chemistry 2008;16:902-8. [DOI: 10.1016/j.bmc.2007.10.020] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 0.8] [Reference Citation Analysis]
191 Johnson JW, Evanoff DP, Savard ME, Lange G, Ramadhar TR, Assoud A, Taylor NJ, Dmitrienko GI. Cyclobutanone Mimics of Penicillins: Effects of Substitution on Conformation and Hemiketal Stability. J Org Chem 2008;73:6970-82. [DOI: 10.1021/jo801274m] [Cited by in Crossref: 33] [Cited by in F6Publishing: 26] [Article Influence: 2.4] [Reference Citation Analysis]
192 Fabian L, Martini MF, Sarduy ES, Estrin DA, Moglioni AG. Evaluation of quinoxaline compounds as ligands of a site adjacent to S2 (AS2) of cruzain. Bioorganic & Medicinal Chemistry Letters 2019;29:2197-202. [DOI: 10.1016/j.bmcl.2019.06.046] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
193 Odeny DA, Stich B, Gebhardt C. Physical organization of mixed protease inhibitor gene clusters, coordinated expression and association with resistance to late blight at the StKI locus on potato chromosome III. Plant Cell Environ 2010;33:2149-61. [PMID: 20716067 DOI: 10.1111/j.1365-3040.2010.02213.x] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 1.8] [Reference Citation Analysis]
194 Kukric Z, Zabic M. Trypsin inhibition by ferrocene. Acta per tech 2005. [DOI: 10.2298/apt0536203k] [Cited by in Crossref: 1] [Article Influence: 0.1] [Reference Citation Analysis]
195 Brameld KA, Kuhn B, Reuter DC, Stahl M. Small molecule conformational preferences derived from crystal structure data. A medicinal chemistry focused analysis. J Chem Inf Model 2008;48:1-24. [PMID: 18183967 DOI: 10.1021/ci7002494] [Cited by in Crossref: 266] [Cited by in F6Publishing: 224] [Article Influence: 19.0] [Reference Citation Analysis]
196 Chappell KJ, Nall TA, Stoermer MJ, Fang N, Tyndall JD, Fairlie DP, Young PR. Site-directed Mutagenesis and Kinetic Studies of the West Nile Virus NS3 Protease Identify Key Enzyme-Substrate Interactions. Journal of Biological Chemistry 2005;280:2896-903. [DOI: 10.1074/jbc.m409931200] [Cited by in Crossref: 49] [Cited by in F6Publishing: 19] [Article Influence: 2.9] [Reference Citation Analysis]
197 Li Q, Kang C. Structures and Dynamics of Dengue Virus Nonstructural Membrane Proteins. Membranes 2022;12:231. [DOI: 10.3390/membranes12020231] [Reference Citation Analysis]
198 Rönn R, Gossas T, Sabnis YA, Daoud H, Åkerblom E, Danielson UH, Sandström A. Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors. Bioorganic & Medicinal Chemistry 2007;15:4057-68. [DOI: 10.1016/j.bmc.2007.03.089] [Cited by in Crossref: 35] [Cited by in F6Publishing: 28] [Article Influence: 2.3] [Reference Citation Analysis]
199 Fairlie DP, Tyndall JDA, Reid RC, Wong AK, Abbenante G, Scanlon MJ, March DR, Bergman DA, Chai CLL, Burkett BA. Conformational Selection of Inhibitors and Substrates by Proteolytic Enzymes:  Implications for Drug Design and Polypeptide Processing. J Med Chem 2000;43:1271-81. [DOI: 10.1021/jm990315t] [Cited by in Crossref: 121] [Cited by in F6Publishing: 107] [Article Influence: 5.5] [Reference Citation Analysis]
200 Hoppe-seyler F, Crnkovic-mertens I, Denk C, Fitscher B, Klevenz B, Tomai E, Butz K. Peptide aptamers: new tools to study protein interactions. The Journal of Steroid Biochemistry and Molecular Biology 2001;78:105-11. [DOI: 10.1016/s0960-0760(01)00085-1] [Cited by in Crossref: 9] [Article Influence: 0.4] [Reference Citation Analysis]
201 Jamloki A, Karthikeyan C, Hari Narayana Moorthy N, Trivedi P. QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase. Bioorganic & Medicinal Chemistry Letters 2006;16:3847-54. [DOI: 10.1016/j.bmcl.2006.04.014] [Cited by in Crossref: 10] [Cited by in F6Publishing: 7] [Article Influence: 0.6] [Reference Citation Analysis]
202 Nakamura M, Inoue J. Exploration of peptidyl hydrazones as water-soluble calpain inhibitors. Bioorganic & Medicinal Chemistry Letters 2002;12:1603-6. [DOI: 10.1016/s0960-894x(02)00226-3] [Cited by in Crossref: 12] [Article Influence: 0.6] [Reference Citation Analysis]
203 Cornelio VE, de Moraes MC, Domingues VDC, Fernandes JB, da Silva MFDGF, Cass QB, Vieira PC. Cathepsin D immobilized capillary reactors for on-flow screening assays. Journal of Pharmaceutical and Biomedical Analysis 2018;151:252-9. [DOI: 10.1016/j.jpba.2018.01.001] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 1.8] [Reference Citation Analysis]
204 Kobayashi H, Eickhoff JA, Zakarian A. Synthesis of 2-Aminoazoles from Thioesters via α-Heterosubstituted Ketones by Copper-Mediated Cross-Coupling. J Org Chem 2015;80:9989-99. [PMID: 26378626 DOI: 10.1021/acs.joc.5b01558] [Cited by in Crossref: 19] [Cited by in F6Publishing: 15] [Article Influence: 2.7] [Reference Citation Analysis]
205 Annedi SC, Li W, Samson S, Kotra LP. Design and Synthesis of Novel Fluoropeptidomimetics as Potential Mimics of the Transition State during Peptide Hydrolysis. J Org Chem 2003;68:1043-9. [DOI: 10.1021/jo026310c] [Cited by in Crossref: 24] [Cited by in F6Publishing: 17] [Article Influence: 1.3] [Reference Citation Analysis]
206 Olyaei AJ, deMattos AM, Bennett WM. Renal toxicity of protease inhibitors: . Current Opinion in Nephrology and Hypertension 2000;9:473-6. [DOI: 10.1097/00041552-200009000-00003] [Cited by in Crossref: 27] [Cited by in F6Publishing: 18] [Article Influence: 1.2] [Reference Citation Analysis]
207 Al-Awadhi FH, Luesch H. Targeting eukaryotic proteases for natural products-based drug development. Nat Prod Rep 2020;37:827-60. [PMID: 32519686 DOI: 10.1039/c9np00060g] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 7.0] [Reference Citation Analysis]
208 Marshall GR. Peptide interactions with G-protein coupled receptors. Biopolymers 2001;60:246-77. [PMID: 11774230 DOI: 10.1002/1097-0282(2001)60:3<246::AID-BIP10044>3.0.CO;2-V] [Cited by in Crossref: 47] [Cited by in F6Publishing: 14] [Article Influence: 2.4] [Reference Citation Analysis]
209 Mulchande J, Guedes RC, Tsang W, Page MI, Moreira R, Iley J. Azetidine-2,4-diones (4-Oxo-β-lactams) as Scaffolds for Designing Elastase Inhibitors. J Med Chem 2008;51:1783-90. [DOI: 10.1021/jm701257h] [Cited by in Crossref: 23] [Cited by in F6Publishing: 20] [Article Influence: 1.6] [Reference Citation Analysis]
210 Mak CC, Brik A, Lerner DL, Elder JH, Morris GM, Olson AJ, Wong C. Design and synthesis of broad-Based mono- and bi- cyclic inhibitors of FIV and HIV proteases. Bioorganic & Medicinal Chemistry 2003;11:2025-40. [DOI: 10.1016/s0968-0896(03)00054-3] [Cited by in Crossref: 17] [Cited by in F6Publishing: 4] [Article Influence: 0.9] [Reference Citation Analysis]
211 Shang L, Wang Q, Fang H, Mu J, Wang X, Yuan Y, Wang B, Xu W. Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN). Bioorganic & Medicinal Chemistry 2008;16:9984-90. [DOI: 10.1016/j.bmc.2008.10.025] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 1.3] [Reference Citation Analysis]
212 Piergies N, Kim Y, Proniewicz E. Potential-dependant SERS interaction of ortho-substituted N-benzylamino(boronphenyl)methylphosphonic acid with Ag, Au, and Cu electrode surfaces. Vibrational Spectroscopy 2016;83:94-100. [DOI: 10.1016/j.vibspec.2016.01.012] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.8] [Reference Citation Analysis]
213 Min GK, Hernández D, Skrydstrup T. Efficient routes to carbon-silicon bond formation for the synthesis of silicon-containing peptides and azasilaheterocycles. Acc Chem Res 2013;46:457-70. [PMID: 23214467 DOI: 10.1021/ar300200h] [Cited by in Crossref: 108] [Cited by in F6Publishing: 80] [Article Influence: 10.8] [Reference Citation Analysis]
214 Aoki S, Tomiyama Y, Kageyama Y, Yamada Y, Shiro M, Kimura E. Photolysis of the sulfonamide bond of metal complexes of N-dansyl-1,4,7,10-tetraazacyclododecane in aqueous solution: a mechanistic study and application to the photorepair of cis,syn-cyclobutane thymine photodimer. Chem Asian J 2009;4:561-73. [PMID: 19165842 DOI: 10.1002/asia.200800428] [Cited by in Crossref: 15] [Cited by in F6Publishing: 9] [Article Influence: 1.2] [Reference Citation Analysis]
215 Kemnitzer W, Drewe J, Jiang S, Zhang H, Wang Y, Zhao J, Jia S, Herich J, Labreque D, Storer R, Meerovitch K, Bouffard D, Rej R, Denis R, Blais C, Lamothe S, Attardo G, Gourdeau H, Tseng B, Kasibhatla S, Cai SX. Discovery of 4-Aryl-4 H -chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group. J Med Chem 2004;47:6299-310. [DOI: 10.1021/jm049640t] [Cited by in Crossref: 199] [Cited by in F6Publishing: 167] [Article Influence: 11.1] [Reference Citation Analysis]
216 Smith RA, Bhargava A, Browe C, Chen J, Dumas J, Hatoum-mokdad H, Romero R. Discovery and parallel synthesis of a new class of cathepsin k inhibitors. Bioorganic & Medicinal Chemistry Letters 2001;11:2951-4. [DOI: 10.1016/s0960-894x(01)00600-x] [Cited by in Crossref: 10] [Article Influence: 0.5] [Reference Citation Analysis]
217 Peterlin-mašič L, Kikelj D. Arginine mimetics. Tetrahedron 2001;57:7073-105. [DOI: 10.1016/s0040-4020(01)00507-5] [Cited by in Crossref: 116] [Article Influence: 5.5] [Reference Citation Analysis]
218 Maignan S, Guilloteau J, Choi-sledeski YM, Becker MR, Ewing WR, Pauls HW, Spada AP, Mikol V. Molecular Structures of Human Factor Xa Complexed with Ketopiperazine Inhibitors:  Preference for a Neutral Group in the S1 Pocket. J Med Chem 2003;46:685-90. [DOI: 10.1021/jm0203837] [Cited by in Crossref: 93] [Cited by in F6Publishing: 79] [Article Influence: 4.9] [Reference Citation Analysis]
219 Halili MA, Ruiz-Gómez G, Le GT, Abbenante G, Fairlie DP. Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. Biochemistry 2009;48:8466-72. [PMID: 19642650 DOI: 10.1021/bi900679r] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
220 Slade JS, James A.vivelo,, Parker DJ, Bajwa J, Liu H, Girgis M, Parker DT, Repič O, Blacklock T. A Practical Synthesis of the Dual Matrix Metalloprotease/Tumor Necrosis Factor Inhibitor MMP090. Org Process Res Dev 2005;9:608-20. [DOI: 10.1021/op050066k] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
221 Gupta SP. Quantitative Structure−Activity Relationship Studies on Zinc-Containing Metalloproteinase Inhibitors. Chem Rev 2007;107:3042-87. [DOI: 10.1021/cr030448t] [Cited by in Crossref: 61] [Cited by in F6Publishing: 46] [Article Influence: 4.1] [Reference Citation Analysis]
222 Lyu J, Liu Y, An T, Liu Y, Wang M, Song Y, Zheng F, Wu D, Zhang Y, Deng S. Purification and characterization of a trypsin inhibitor from the seeds of Artocarpus heterophyllus Lam. Acta Biochimica et Biophysica Sinica 2015;47:376-82. [DOI: 10.1093/abbs/gmv022] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.4] [Reference Citation Analysis]
223 Kokotos G, Kotsovolou S, Verger R. Novel Trifluoromethyl Ketones as Potent Gastric Lipase Inhibitors. ChemBioChem 2003;4:90-5. [DOI: 10.1002/cbic.200390019] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
224 John S, Thangapandian S, Sakkiah S, Lee KW. Discovery of potential pancreatic cholesterol esterase inhibitors using pharmacophore modelling, virtual screening, and optimization studies. Journal of Enzyme Inhibition and Medicinal Chemistry 2011;26:535-45. [DOI: 10.3109/14756366.2010.535795] [Cited by in Crossref: 16] [Cited by in F6Publishing: 12] [Article Influence: 1.3] [Reference Citation Analysis]
225 Sirisoma N, Pervin A, Nguyen B, Crogan-grundy C, Kasibhatla S, Tseng B, Drewe J, Cai SX. Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure–activity relationships of the 2-aryl group. Bioorganic & Medicinal Chemistry Letters 2009;19:2305-9. [DOI: 10.1016/j.bmcl.2009.02.074] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
226 Banner DW. Not just an active site. Nature 2000;404:449-50. [DOI: 10.1038/35006540] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
227 Xue C, He G, Fu C, Xue L, Lin Z, Ma S. The Reaction of Carboxylic Acid Esters with RfMgBr: A Convenient Synthesis of Perfluoroalkyl Ketones. Eur J Org Chem 2010;2010:7012-9. [DOI: 10.1002/ejoc.201000887] [Cited by in Crossref: 9] [Article Influence: 0.8] [Reference Citation Analysis]
228 Lv Y, Zhang J, Wu H, Zhao S, Song Y, Wang S, Wang B, Lv G, Ma X. A protease inhibition strategy based on acceleration of autolysis. Chem Commun 2015;51:5959-62. [DOI: 10.1039/c5cc01448d] [Cited by in Crossref: 5] [Article Influence: 0.7] [Reference Citation Analysis]
229 Sukuru SC, Nigsch F, Quancard J, Renatus M, Chopra R, Brooijmans N, Mikhailov D, Deng Z, Cornett A, Jenkins JL, Hommel U, Davies JW, Glick M. A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space. Protein Sci 2010;19:2096-109. [PMID: 20799349 DOI: 10.1002/pro.490] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
230 Wang K, Yang T, Wu Q, Zhao X, Nice EC, Huang C. Chemistry-based functional proteomics for drug target deconvolution. Expert Rev Proteomics 2012;9:293-310. [PMID: 22809208 DOI: 10.1586/epr.12.19] [Cited by in Crossref: 25] [Cited by in F6Publishing: 19] [Article Influence: 2.8] [Reference Citation Analysis]
231 Yamagishi T, Ichikawa H, Haruki T, Yokomatsu T. Diastereoselective Synthesis of α,β′-Disubstituted Aminomethyl(2-carboxyethyl)phosphinates as Phosphinyl Dipeptide Isosteres. Org Lett 2008;10:4347-50. [DOI: 10.1021/ol801743d] [Cited by in Crossref: 20] [Cited by in F6Publishing: 15] [Article Influence: 1.4] [Reference Citation Analysis]
232 Das BC, Mahalingam SM, Evans T. Design and synthesis of novel pinacolylboronate containing combretastatin 'antimitotic agent' analogues. Tetrahedron Lett 2009;50:3031-4. [PMID: 20037629 DOI: 10.1016/j.tetlet.2009.04.003] [Cited by in Crossref: 10] [Cited by in F6Publishing: 7] [Article Influence: 0.8] [Reference Citation Analysis]
233 Białas A, Grembecka J, Krowarsch D, Otlewski J, Potempa J, Mucha A. Exploring the Sn binding pockets in gingipains by newly developed inhibitors: structure-based design, chemistry, and activity. J Med Chem 2006;49:1744-53. [PMID: 16509589 DOI: 10.1021/jm0600141] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
234 Maly DJ, Leonetti F, Backes BJ, Dauber DS, Harris JL, Craik CS, Ellman JA. Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore. J Org Chem 2002;67:910-5. [PMID: 11856036 DOI: 10.1021/jo016140o] [Cited by in Crossref: 107] [Cited by in F6Publishing: 96] [Article Influence: 5.4] [Reference Citation Analysis]
235 Gupta S, Kumaran S. A quantitative structure–activity relationship study on Clostridium histolyticum collagenase inhibitors. Bioorganic & Medicinal Chemistry 2003;11:3065-71. [DOI: 10.1016/s0968-0896(03)00275-x] [Cited by in Crossref: 12] [Cited by in F6Publishing: 1] [Article Influence: 0.6] [Reference Citation Analysis]
236 Quéléver G, Bihel F, Kraus JL. New beta-strand macrocyclic peptidomimetic analogues containing alpha-(O-, S- or NH-)aryl substituted glycine residues: synthesis, chemical and enzymatic properties. Org Biomol Chem 2003;1:1676-83. [PMID: 12926354 DOI: 10.1039/b211644h] [Cited by in Crossref: 2] [Article Influence: 0.1] [Reference Citation Analysis]
237 Lama T, Del Valle SE, Genest N, Lubell WD. Alcohols as Replacements of the Central Amide in β-Turns, Synthesis of Pro-Aib Hydroxyethylene Isostere and Analysis in Model β-Turn Peptides. Int J Pept Res Ther 2007;13:355-66. [DOI: 10.1007/s10989-007-9093-0] [Cited by in Crossref: 10] [Article Influence: 0.7] [Reference Citation Analysis]
238 Citron M. Alzheimer's disease: treatments in discovery and development. Nat Neurosci 2002;5:1055-7. [DOI: 10.1038/nn940] [Cited by in Crossref: 103] [Cited by in F6Publishing: 96] [Article Influence: 5.2] [Reference Citation Analysis]
239 Katritzky AR, Meher G, Narindoshvili T. Efficient Synthesis of Peptides by Extension at the N- and C-Terminii of Arginine. J Org Chem 2008;73:7153-8. [DOI: 10.1021/jo800805w] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
240 Guerrini A, Varchi G, Daniele R, Samorì C, Battaglia A. Synthesis of chiral β2,2,3-3-amino-2-hydroxyalkanoates and 3-alkyl-3-hydroxy-β-lactams by double asymmetric induction. Tetrahedron 2007;63:7949-69. [DOI: 10.1016/j.tet.2007.05.069] [Cited by in Crossref: 18] [Cited by in F6Publishing: 11] [Article Influence: 1.2] [Reference Citation Analysis]
241 Bhattacharya AK, Rana KC. Design, synthesis and biological evaluation of peptidyl-vinylaminophosphonates as novel cysteine protease inhibitors. Bioorganic & Medicinal Chemistry 2011;19:7129-35. [DOI: 10.1016/j.bmc.2011.09.058] [Cited by in Crossref: 13] [Cited by in F6Publishing: 9] [Article Influence: 1.2] [Reference Citation Analysis]
242 Bi X, Lai SL, Yang K. Liquid Crystal Multiplexed Protease Assays Reporting Enzymatic Activities as Optical Bar Charts. Anal Chem 2009;81:5503-9. [DOI: 10.1021/ac900793w] [Cited by in Crossref: 46] [Cited by in F6Publishing: 41] [Article Influence: 3.5] [Reference Citation Analysis]
243 Sabnis YA, Desai PV, Rosenthal PJ, Avery MA. Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies. Protein Sci 2003;12:501-9. [PMID: 12592020 DOI: 10.1110/ps.0228103] [Cited by in Crossref: 44] [Cited by in F6Publishing: 40] [Article Influence: 2.3] [Reference Citation Analysis]
244 Wood WJ, Patterson AW, Tsuruoka H, Jain RK, Ellman JA. Substrate activity screening: a fragment-based method for the rapid identification of nonpeptidic protease inhibitors. J Am Chem Soc 2005;127:15521-7. [PMID: 16262416 DOI: 10.1021/ja0547230] [Cited by in Crossref: 94] [Cited by in F6Publishing: 83] [Article Influence: 5.9] [Reference Citation Analysis]
245 Sibi MP, Hasegawa H. An Efficient Method for Synthesis of Succinate-Based MMP Inhibitors. Org Lett 2002;4:3347-9. [DOI: 10.1021/ol026331t] [Cited by in Crossref: 25] [Cited by in F6Publishing: 13] [Article Influence: 1.3] [Reference Citation Analysis]
246 Bouzide A, Sauvé G, Yelle J. Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies. Bioorg Med Chem Lett 2005;15:1509-13. [PMID: 15713418 DOI: 10.1016/j.bmcl.2004.12.068] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.3] [Reference Citation Analysis]
247 Ehmke V, Quinsaat JEQ, Rivera-fuentes P, Heindl C, Freymond C, Rottmann M, Brun R, Schirmeister T, Diederich F. Tuning and predicting biological affinity: aryl nitriles as cysteine protease inhibitors. Org Biomol Chem 2012;10:5764. [DOI: 10.1039/c2ob00034b] [Cited by in Crossref: 38] [Cited by in F6Publishing: 32] [Article Influence: 3.8] [Reference Citation Analysis]
248 Zhou Y, Zhang Y. Serine protease acylation proceeds with a subtle re-orientation of the histidine ring at the tetrahedral intermediate. Chem Commun (Camb) 2011;47:1577-9. [PMID: 21116528 DOI: 10.1039/c0cc04112b] [Cited by in Crossref: 35] [Cited by in F6Publishing: 12] [Article Influence: 2.9] [Reference Citation Analysis]
249 Ghosh AK, Anderson DD, Mitsuya H. The FDA Approved HIV ‐1 Protease Inhibitors for Treatment of HIV / AIDS. Burger's Medicinal Chemistry and Drug Discovery. Wiley; 2003. pp. 1-74. [DOI: 10.1002/0471266949.bmc224] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
250 Welser K, Adsley R, Moore BM, Chan WC, Aylott JW. Protease sensing with nanoparticle based platforms. Analyst 2011;136:29-41. [PMID: 20877821 DOI: 10.1039/c0an00429d] [Cited by in Crossref: 57] [Cited by in F6Publishing: 9] [Article Influence: 4.8] [Reference Citation Analysis]
251 Winum JY, Scozzafava A, Montero JL, Supuran CT. Therapeutic potential of sulfamides as enzyme inhibitors. Med Res Rev 2006;26:767-92. [PMID: 16710859 DOI: 10.1002/med.20068] [Cited by in Crossref: 143] [Cited by in F6Publishing: 131] [Article Influence: 8.9] [Reference Citation Analysis]
252 Fernandez M, Ahmad S, Abreu JI, Sarai A. Large-scale recognition of high-affinity protease–inhibitor complexes using topological autocorrelation and support vector machines. Molecular Simulation 2015;42:420-33. [DOI: 10.1080/08927022.2015.1059937] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
253 Barry NP, Sadler PJ. Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium: biological relevance and synthetic strategies. Chem Soc Rev. 2012;41:3264-3279. [PMID: 22307021 DOI: 10.1039/c2cs15300a] [Cited by in Crossref: 96] [Cited by in F6Publishing: 83] [Article Influence: 9.6] [Reference Citation Analysis]
254 Cheng RM, Tang XP, Long AL, Mwangi J, Lai R, Sun RP, Long CB, Zhang ZQ. Purification and characterization of a novel anti-coagulant from the leech Hirudinaria manillensis. Zool Res 2019;40:205-10. [PMID: 31011131 DOI: 10.24272/j.issn.2095-8137.2019.037] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
255 Allen KN, Whitman CP. The Birth of Genomic Enzymology: Discovery of the Mechanistically Diverse Enolase Superfamily. Biochemistry 2021;60:3515-28. [PMID: 34664940 DOI: 10.1021/acs.biochem.1c00494] [Reference Citation Analysis]
256 Svenson J, Stensen W, Brandsdal BO, Haug BE, Monrad J, Svendsen JS. Antimicrobial peptides with stability toward tryptic degradation. Biochemistry 2008;47:3777-88. [PMID: 18307313 DOI: 10.1021/bi7019904] [Cited by in Crossref: 88] [Cited by in F6Publishing: 78] [Article Influence: 6.3] [Reference Citation Analysis]
257 van Kasteren SI, Berlin I, Colbert JD, Keane D, Ovaa H, Watts C. A multifunctional protease inhibitor to regulate endolysosomal function. ACS Chem Biol 2011;6:1198-204. [PMID: 21910425 DOI: 10.1021/cb200292c] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 1.4] [Reference Citation Analysis]
258 Southan C. A genomic perspective on human proteases as drug targets. Drug Discovery Today 2001;6:681-8. [DOI: 10.1016/s1359-6446(01)01793-7] [Cited by in Crossref: 62] [Cited by in F6Publishing: 15] [Article Influence: 3.0] [Reference Citation Analysis]
259 Thorstensson F, Kvarnström I, Musil D, Nilsson I, Samuelsson B. Synthesis of Novel Thrombin Inhibitors. Use of Ring-Closing Metathesis Reactions for Synthesis of P2 Cyclopentene- and Cyclohexenedicarboxylic Acid Derivatives. J Med Chem 2003;46:1165-79. [DOI: 10.1021/jm021065a] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 1.1] [Reference Citation Analysis]
260 Kapui Z, Varga M, Urban-Szabo K, Mikus E, Szabo T, Szeredi J, Batori S, Finance O, Aranyi P. Biochemical and pharmacological characterization of 2-(9-(2-piperidinoethoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yloxymethyl)-4-(1-methylethyl)-6-methoxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide (SSR69071), a novel, orally active elastase inhibitor. J Pharmacol Exp Ther 2003;305:451-9. [PMID: 12606659 DOI: 10.1124/jpet.102.044263] [Cited by in Crossref: 27] [Cited by in F6Publishing: 14] [Article Influence: 1.4] [Reference Citation Analysis]
261 Balomenou S, Koutsioulis D, Tomatsidou A, Tzanodaskalaki M, Petratos K, Bouriotis V. Polysaccharide deacetylases serve as new targets for the design of inhibitors against Bacillus anthracis and Bacillus cereus. Bioorganic & Medicinal Chemistry 2018;26:3845-51. [DOI: 10.1016/j.bmc.2018.06.045] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
262 Brzozowski Z, Sączewski F, Gdaniec M. Synthesis, molecular structure and anticancer activity of 1-allyl-3-amino-2-(4-chloro-2-mercaptobenzenesulphonyl)guanidine derivatives. European Journal of Medicinal Chemistry 2002;37:285-93. [DOI: 10.1016/s0223-5234(02)01341-7] [Cited by in Crossref: 34] [Cited by in F6Publishing: 1] [Article Influence: 1.7] [Reference Citation Analysis]
263 Bandyopadhyay A, Malik A, Kumar MG, Gopi HN. Exploring β-Hydroxy γ-Amino Acids (Statines) in the Design of Hybrid Peptide Foldamers. Org Lett 2014;16:294-7. [DOI: 10.1021/ol403290h] [Cited by in Crossref: 18] [Cited by in F6Publishing: 13] [Article Influence: 2.0] [Reference Citation Analysis]
264 Supuran CT, Scozzafava A, Clare BW. Bacterial protease inhibitors. Med Res Rev 2002;22:329-72. [DOI: 10.1002/med.10007] [Cited by in Crossref: 117] [Cited by in F6Publishing: 101] [Article Influence: 5.9] [Reference Citation Analysis]
265 Gupta S, Senapati S. Mechanism of inhibition of drug-resistant HIV-1 protease clinical isolates by TMC310911: A molecular dynamics study. Journal of Molecular Structure 2019;1198:126893. [DOI: 10.1016/j.molstruc.2019.126893] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 1.3] [Reference Citation Analysis]
266 Le GT, Abbenante G, Fairlie DP. Profiling the enzymatic properties and inhibition of human complement factor B. J Biol Chem 2007;282:34809-16. [PMID: 17921140 DOI: 10.1074/jbc.M705646200] [Cited by in Crossref: 17] [Cited by in F6Publishing: 7] [Article Influence: 1.1] [Reference Citation Analysis]
267 Weik S, Luksch T, Evers A, Böttcher J, Sotriffer CA, Hasilik A, Löffler HG, Klebe G, Rademann J. The potential of P1 site alterations in peptidomimetic protease inhibitors as suggested by virtual screening and explored by the use of C-C-coupling reagents. ChemMedChem 2006;1:445-57. [PMID: 16892380 DOI: 10.1002/cmdc.200500027] [Cited by in Crossref: 29] [Cited by in F6Publishing: 21] [Article Influence: 1.8] [Reference Citation Analysis]
268 Ahsan M, Senapati S. Water Plays a Cocatalytic Role in Epoxide Ring Opening Reaction in Aspartate Proteases: A QM/MM Study. J Phys Chem B 2019;123:7955-64. [PMID: 31468966 DOI: 10.1021/acs.jpcb.9b04575] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
269 Loughlin WA, Tyndall JDA, Glenn MP, Fairlie DP. Beta-Strand Mimetics. Chem Rev 2004;104:6085-118. [DOI: 10.1021/cr040648k] [Cited by in Crossref: 179] [Cited by in F6Publishing: 163] [Article Influence: 9.9] [Reference Citation Analysis]
270 Zhang S, Chen C, Qin X, Zhang Q, Liu J, Zhu J, Gao Y, Li L, Huang W. Ultrasensitive detection of trypsin activity and inhibitor screening based on the electron transfer between phosphorescence copper nanocluster and cytochrome c. Talanta 2018;189:92-9. [PMID: 30086981 DOI: 10.1016/j.talanta.2018.06.026] [Cited by in Crossref: 16] [Cited by in F6Publishing: 14] [Article Influence: 4.0] [Reference Citation Analysis]
271 Verner E, Katz BA, Spencer JR, Allen D, Hataye J, Hruzewicz W, Hui HC, Kolesnikov A, Li Y, Luong C, Martelli A, Radika K, Rai R, She M, Shrader W, Sprengeler PA, Trapp S, Wang J, Young WB, Mackman RL. Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode:  Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa. J Med Chem 2001;44:2753-71. [DOI: 10.1021/jm0100638] [Cited by in Crossref: 100] [Cited by in F6Publishing: 78] [Article Influence: 4.8] [Reference Citation Analysis]
272 Gopinath P, Yadav RK, Shukla PK, Srivastava K, Puri SK, Muraleedharan KM. Broad spectrum anti-infective properties of benzisothiazolones and the parallels in their anti-bacterial and anti-fungal effects. Bioorg Med Chem Lett 2017;27:1291-5. [PMID: 28159413 DOI: 10.1016/j.bmcl.2017.01.027] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 1.4] [Reference Citation Analysis]
273 Yadav MR, Shinde AK, Chouhan BS, Giridhar R, Menard R. Peptidomimetic 2-cyanopyrrolidines as potent selective cathepsin L inhibitors. J Enzyme Inhib Med Chem 2008;23:190-7. [PMID: 18343903 DOI: 10.1080/14756360701504842] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
274 Hanessian S, Gauchet C, Charron G, Marin J, Nakache P. Design and Synthesis of Diversely Substituted Azacyclic Inhibitors of Endothelin Converting Enzyme. J Org Chem 2006;71:2760-78. [DOI: 10.1021/jo052649y] [Cited by in Crossref: 18] [Cited by in F6Publishing: 12] [Article Influence: 1.1] [Reference Citation Analysis]
275 Santos MA, Marques S, Vullo D, Innocenti A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: Inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties. Bioorganic & Medicinal Chemistry Letters 2007;17:1538-43. [DOI: 10.1016/j.bmcl.2006.12.107] [Cited by in Crossref: 27] [Cited by in F6Publishing: 25] [Article Influence: 1.8] [Reference Citation Analysis]
276 Chandrasekhar V, Boomishankar R, Nagendran S. Recent Developments in the Synthesis and Structure of Organosilanols. Chem Rev 2004;104:5847-910. [DOI: 10.1021/cr0306135] [Cited by in Crossref: 236] [Cited by in F6Publishing: 148] [Article Influence: 13.1] [Reference Citation Analysis]
277 Chakraborty TK, Ghosh S, Rao MHVR, Kunwar AC, Cho H, Ghosh AK. 2,5-Anhydro sugar diacid and 2,5-anhydro sugar diamine based C 2 symmetric peptidomimetics as potential HIV-1 protease inhibitors. Tetrahedron Lett 2000;41:10121-5. [PMID: 30386001 DOI: 10.1016/S0040-4039(00)01803-7] [Cited by in Crossref: 18] [Cited by in F6Publishing: 1] [Article Influence: 0.8] [Reference Citation Analysis]
278 Byrd CM, Hruby DE. Viral proteinases: targets of opportunity. Drug Dev Res 2006;67:501-10. [DOI: 10.1002/ddr.20114] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
279 Stoermer MJ, Chappell KJ, Liebscher S, Jensen CM, Gan CH, Gupta PK, Xu W, Young PR, Fairlie DP. Potent Cationic Inhibitors of West Nile Virus NS2B/NS3 Protease With Serum Stability, Cell Permeability and Antiviral Activity. J Med Chem 2008;51:5714-21. [DOI: 10.1021/jm800503y] [Cited by in Crossref: 64] [Cited by in F6Publishing: 59] [Article Influence: 4.6] [Reference Citation Analysis]
280 Ganesh Kumar M, Benke SN, Poopathi Raja KM, Gopi HN. Engineering polypeptide folding through trans double bonds: transformation of miniature β-meanders to hybrid helices. Chem Commun 2015;51:13397-9. [DOI: 10.1039/c5cc04523a] [Cited by in Crossref: 4] [Article Influence: 0.6] [Reference Citation Analysis]
281 Chen X, Fan Z, Chen Y, Fang X, Sha X. Retro-inverso carbohydrate mimetic peptides with annexin1-binding selectivity, are stable in vivo, and target tumor vasculature. PLoS One 2013;8:e80390. [PMID: 24312470 DOI: 10.1371/journal.pone.0080390] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
282 Kappel JC, Barany G. Backbone amide linker (BAL) strategy for Nalpha-9-fluorenylmethoxycarbonyl (Fmoc) solid-phase synthesis of peptide aldehydes. J Pept Sci 2005;11:525-35. [PMID: 16001455 DOI: 10.1002/psc.614] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 1.1] [Reference Citation Analysis]
283 Molteni M, Volonterio A, Zanda M. Stereocontrolled Synthesis of ψ[CH(CF 3 )NH]Gly-Peptides. Org Lett 2003;5:3887-90. [DOI: 10.1021/ol0354730] [Cited by in Crossref: 60] [Cited by in F6Publishing: 49] [Article Influence: 3.2] [Reference Citation Analysis]
284 Coria LM, Ibañez AE, Tkach M, Sabbione F, Bruno L, Carabajal MV, Berguer PM, Barrionuevo P, Schillaci R, Trevani AS, Giambartolomei GH, Pasquevich KA, Cassataro J. A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses. J Immunol 2016;196:4014-29. [PMID: 27084100 DOI: 10.4049/jimmunol.1501188] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 2.7] [Reference Citation Analysis]
285 Drewe J, Cai SX. Cell-based apoptosis assays in oncology drug discovery. Expert Opinion on Drug Discovery 2010;5:583-96. [DOI: 10.1517/17460441.2010.486829] [Cited by in Crossref: 10] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
286 Chino M, Wakao M, Ellman JA. Efficient method to prepare hydroxyethylamine-based aspartyl protease inhibitors with diverse P1 side chains. Tetrahedron 2002;58:6305-10. [DOI: 10.1016/s0040-4020(02)00629-4] [Cited by in Crossref: 9] [Article Influence: 0.5] [Reference Citation Analysis]
287 Poulain N, Dez I, Perrio C, Lasne M, Prud’homme M, Nakache E. Microspheres based on inulin for the controlled release of serine protease inhibitors: preparation, characterization and in vitro release. Journal of Controlled Release 2003;92:27-38. [DOI: 10.1016/s0168-3659(03)00251-7] [Cited by in Crossref: 40] [Cited by in F6Publishing: 7] [Article Influence: 2.1] [Reference Citation Analysis]
288 Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LCA, van Montfort RLM. Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors. J Med Chem 2006;49:1346-55. [DOI: 10.1021/jm050850v] [Cited by in Crossref: 106] [Cited by in F6Publishing: 82] [Article Influence: 6.6] [Reference Citation Analysis]
289 Singh SB, Ondeyka JG, Tsipouras N, Ruby C, Sardana V, Schulman M, Sanchez M, Pelaez F, Stahlhut MW, Munshi S, Olsen DB, Lingham RB. Hinnuliquinone, a C2-symmetric dimeric non-peptide fungal metabolite inhibitor of HIV-1 protease. Biochem Biophys Res Commun 2004;324:108-13. [PMID: 15464989 DOI: 10.1016/j.bbrc.2004.08.234] [Cited by in Crossref: 24] [Cited by in F6Publishing: 14] [Article Influence: 1.3] [Reference Citation Analysis]
290 Hackbarth CJ, Chen DZ, Lewis JG, Clark K, Mangold JB, Cramer JA, Margolis PS, Wang W, Koehn J, Wu C, Lopez S, Withers G 3rd, Gu H, Dunn E, Kulathila R, Pan SH, Porter WL, Jacobs J, Trias J, Patel DV, Weidmann B, White RJ, Yuan Z. N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity. Antimicrob Agents Chemother 2002;46:2752-64. [PMID: 12183225 DOI: 10.1128/AAC.46.9.2752-2764.2002] [Cited by in Crossref: 79] [Cited by in F6Publishing: 18] [Article Influence: 4.2] [Reference Citation Analysis]
291 Nie X, Wang G. Total synthesis of aeruginosin 298-A analogs containing ring oxygenated variants of 2-carboxy-6-hydroxyoctahydroindole. Tetrahedron 2008;64:5784-93. [DOI: 10.1016/j.tet.2008.03.107] [Cited by in Crossref: 10] [Cited by in F6Publishing: 7] [Article Influence: 0.7] [Reference Citation Analysis]
292 Prichard K, Campkin D, O'brien N, Kato A, Fleet GWJ, Simone MI. Biological activities of 3,4,5-trihydroxypiperidines and their N - and O -derivatives. Chem Biol Drug Des 2018;92:1171-97. [DOI: 10.1111/cbdd.13182] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 3.8] [Reference Citation Analysis]
293 Smith AJ, Zhang X, Leach AG, Houk KN. Beyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteins. J Med Chem 2009;52:225-33. [PMID: 19053779 DOI: 10.1021/jm800498e] [Cited by in Crossref: 128] [Cited by in F6Publishing: 120] [Article Influence: 9.8] [Reference Citation Analysis]
294 Rizzi L, Sundararaman S, Cendic K, Vaiana N, Korde R, Sinha D, Mohmmed A, Malhotra P, Romeo S. Design and synthesis of protein-protein interaction mimics as Plasmodium falciparum cysteine protease, falcipain-2 inhibitors. Eur J Med Chem 2011;46:2083-90. [PMID: 21429631 DOI: 10.1016/j.ejmech.2011.02.061] [Cited by in Crossref: 16] [Cited by in F6Publishing: 12] [Article Influence: 1.5] [Reference Citation Analysis]
295 Augé F, Hornebeck W, Decarme M, Laronze JY. Improved gelatinase a selectivity by novel zinc binding groups containing galardin derivatives. Bioorg Med Chem Lett 2003;13:1783-6. [PMID: 12729664 DOI: 10.1016/s0960-894x(03)00214-2] [Cited by in Crossref: 55] [Cited by in F6Publishing: 9] [Article Influence: 3.1] [Reference Citation Analysis]
296 Walden M, Kreutzmann P, Drögemüller K, John H, Forssmann WG, Hans-Jürgen M. Biochemical features, molecular biology and clinical relevance of the human 15-domain serine proteinase inhibitor LEKTI. Biol Chem 2002;383:1139-41. [PMID: 12437098 DOI: 10.1515/BC.2002.124] [Cited by in Crossref: 12] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
297 Altmann E, Green J, Tintelnot-blomley M. Arylaminoethyl amides as inhibitors of the cysteine protease cathepsin K—investigating P1′ substituents. Bioorganic & Medicinal Chemistry Letters 2003;13:1997-2001. [DOI: 10.1016/s0960-894x(03)00344-5] [Cited by in Crossref: 19] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
298 Petrokova H, Duskova J, Dohnalek J, Skalova T, Vondrackova-buchtelova E, Soucek M, Konvalinka J, Brynda J, Fabry M, Sedlacek J, Hasek J. Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors. Eur J Biochem 2004;271:4451-61. [DOI: 10.1111/j.1432-1033.2004.04384.x] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.4] [Reference Citation Analysis]
299 Van der Veken P, Senten K, Kertèsz I, Haemers A, Augustyns K. β-Fluorinated proline derivatives: potential transition state inhibitors for proline selective serine dipeptidases. Tetrahedron Letters 2003;44:969-72. [DOI: 10.1016/s0040-4039(02)02764-8] [Cited by in Crossref: 21] [Article Influence: 1.1] [Reference Citation Analysis]
300 Sławiński J. Synthesis of a new series of 4-chloro-2-mercapto-5-methylbenzenesulfonamide derivatives with potential antitumor activity. European Journal of Medicinal Chemistry 2004;39:179-88. [DOI: 10.1016/j.ejmech.2003.09.013] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
301 Graven A, St Hilaire PM, Sanderson SJ, Mottram JC, Coombs GH, Meldal M. Combinatorial library of peptide isosters based on Diels-Alder reactions: identification of novel inhibitors against a recombinant cysteine protease from Leishmania mexicana. J Comb Chem 2001;3:441-52. [PMID: 11549362 DOI: 10.1021/cc0001102] [Cited by in Crossref: 27] [Cited by in F6Publishing: 22] [Article Influence: 1.3] [Reference Citation Analysis]
302 Gosalia DN, Salisbury CM, Maly DJ, Ellman JA, Diamond SL. Profiling serine protease substrate specificity with solution phase fluorogenic peptide microarrays. Proteomics 2005;5:1292-8. [DOI: 10.1002/pmic.200401011] [Cited by in Crossref: 91] [Cited by in F6Publishing: 78] [Article Influence: 5.4] [Reference Citation Analysis]
303 Kozakov D, Hall DR, Napoleon RL, Yueh C, Whitty A, Vajda S. New Frontiers in Druggability. J Med Chem 2015;58:9063-88. [PMID: 26230724 DOI: 10.1021/acs.jmedchem.5b00586] [Cited by in Crossref: 62] [Cited by in F6Publishing: 53] [Article Influence: 8.9] [Reference Citation Analysis]
304 Srivastava V, Saxena HO, Shanker K, Kumar J, Luqman S, Gupta M, Khanuja S, Negi AS. Synthesis of gallic acid based naphthophenone fatty acid amides as cathepsin D inhibitors. Bioorganic & Medicinal Chemistry Letters 2006;16:4603-8. [DOI: 10.1016/j.bmcl.2006.06.010] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 1.1] [Reference Citation Analysis]
305 Desai PV, Avery MA. Structural Characterization of Vivapain-2 and Vivapain-3, Cysteine Proteases from Plasmodium vivax : Comparative Protein Modeling and Docking Studies. Journal of Biomolecular Structure and Dynamics 2004;21:781-90. [DOI: 10.1080/07391102.2004.10506968] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.3] [Reference Citation Analysis]
306 Kidd D, Liu Y, Cravatt BF. Profiling serine hydrolase activities in complex proteomes. Biochemistry 2001;40:4005-15. [PMID: 11300781 DOI: 10.1021/bi002579j] [Cited by in Crossref: 265] [Cited by in F6Publishing: 250] [Article Influence: 12.6] [Reference Citation Analysis]
307 Wang SF, Tian GR, Zhang WZ, Jin JY. Characterization of alpha-nitromethyl ketone as a new zinc-binding group based on structural analysis of its complex with carboxypeptidase A. Bioorg Med Chem Lett 2009;19:5009-11. [PMID: 19646864 DOI: 10.1016/j.bmcl.2009.07.060] [Cited by in Crossref: 12] [Cited by in F6Publishing: 4] [Article Influence: 0.9] [Reference Citation Analysis]
308 Alsina J, Albericio F. Solid-phase synthesis of C-terminal modified peptides. Biopolymers 2003;71:454-77. [PMID: 14517898 DOI: 10.1002/bip.10492] [Cited by in Crossref: 54] [Cited by in F6Publishing: 46] [Article Influence: 2.8] [Reference Citation Analysis]
309 Li X, Wang J, Li J, Wu J, Li Y, Zhu H, Fan R, Xu W. Novel aminopeptidase N inhibitors derived from antineoplaston AS2–5 (Part I). Bioorganic & Medicinal Chemistry 2009;17:3053-60. [DOI: 10.1016/j.bmc.2009.02.063] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 0.8] [Reference Citation Analysis]
310 Kline T, Andersen NH, Harwood EA, Bowman J, Malanda A, Endsley S, Erwin AL, Doyle M, Fong S, Harris AL, Mendelsohn B, Mdluli K, Raetz CRH, Stover CK, Witte PR, Yabannavar A, Zhu S. Potent, Novel in Vitro Inhibitors of the Pseudomonasaeruginosa Deacetylase LpxC. J Med Chem 2002;45:3112-29. [DOI: 10.1021/jm010579r] [Cited by in Crossref: 85] [Cited by in F6Publishing: 77] [Article Influence: 4.3] [Reference Citation Analysis]
311 Perlman N, Hazan M, Shokhen M, Albeck A. Peptidyl epoxides extended in the P′ direction as cysteine protease inhibitors: Effect on affinity and mechanism of inhibition. Bioorganic & Medicinal Chemistry 2008;16:9032-9. [DOI: 10.1016/j.bmc.2008.08.031] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 0.6] [Reference Citation Analysis]
312 Tavares FX, Boncek V, Deaton DN, Hassell AM, Long ST, Miller AB, Payne AA, Miller LR, Shewchuk LM, Wells-knecht K, Willard DH, Wright LL, Zhou H. Design of Potent, Selective, and Orally Bioavailable Inhibitors of Cysteine Protease Cathepsin K. J Med Chem 2004;47:588-99. [DOI: 10.1021/jm030373l] [Cited by in Crossref: 35] [Cited by in F6Publishing: 33] [Article Influence: 1.8] [Reference Citation Analysis]
313 Gambini L, Rizzi L, Pedretti A, Taglialatela-Scafati O, Carucci M, Pancotti A, Galli C, Read M, Giurisato E, Romeo S, Russo I. Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region. PLoS One 2015;10:e0142509. [PMID: 26566224 DOI: 10.1371/journal.pone.0142509] [Cited by in Crossref: 23] [Cited by in F6Publishing: 18] [Article Influence: 3.3] [Reference Citation Analysis]
314 Willert M, Benito JM, Meldal M. Solid-Phase Combinatorial Library of Norstatine-Type Isosters by the Nitroaldol Reaction. J Comb Chem 2003;5:91-101. [DOI: 10.1021/cc0100722] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 0.5] [Reference Citation Analysis]
315 Chen KX, Njoroge FG, Prongay A, Pichardo J, Madison V, Girijavallabhan V. Synthesis and biological activity of macrocyclic inhibitors of hepatitis C virus (HCV) NS3 protease. Bioorg Med Chem Lett 2005;15:4475-8. [PMID: 16112859 DOI: 10.1016/j.bmcl.2005.07.033] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 0.8] [Reference Citation Analysis]
316 Marquis RW. Chapter 28. Inhibition of cysteine proteases. Elsevier; 2000. pp. 309-20. [DOI: 10.1016/s0065-7743(00)35029-1] [Cited by in Crossref: 11] [Article Influence: 0.5] [Reference Citation Analysis]
317 Shpak-kraievskyi P, Yin B, Martel A, Dhal R, Dujardin G, Laurent MY. Access to C-protected β-amino-aldehydes via transacetalization of 6-alcoxy tetrahydrooxazinones and use for pseudo-peptide synthesis. Tetrahedron 2012;68:2179-88. [DOI: 10.1016/j.tet.2012.01.002] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.4] [Reference Citation Analysis]
318 Lee KS, Seo SH, Lee YH, Kim HD, Son MH, Chung BY, Lee JY, Jin C, Lee YS. Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors. Bioorg Med Chem Lett 2005;15:2857-60. [PMID: 15911268 DOI: 10.1016/j.bmcl.2005.03.095] [Cited by in Crossref: 39] [Cited by in F6Publishing: 31] [Article Influence: 2.3] [Reference Citation Analysis]
319 Bao R, Zhou CZ, Jiang C, Lin SX, Chi CW, Chen Y. The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. J Biol Chem 2009;284:26676-84. [PMID: 19640842 DOI: 10.1074/jbc.M109.022095] [Cited by in Crossref: 44] [Cited by in F6Publishing: 13] [Article Influence: 3.4] [Reference Citation Analysis]
320 Gupta S, Kumaran S. A quantitative structure–activity relationship study on some series of anthranilic acid-based matrix metalloproteinase inhibitors. Bioorganic & Medicinal Chemistry 2005;13:5454-62. [DOI: 10.1016/j.bmc.2005.05.055] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 0.9] [Reference Citation Analysis]
321 Volonterio A, Chiva G, Fustero S, Piera J, Sanchez Rosello M, Sani M, Zanda M. Stereocontrolled solid-phase synthesis of fluorinated partially-modified retropeptides via tandem aza-Michael/enolate-protonation. Tetrahedron Letters 2003;44:7019-22. [DOI: 10.1016/s0040-4039(03)01787-8] [Cited by in Crossref: 9] [Article Influence: 0.5] [Reference Citation Analysis]
322 Miller KI, Qing C, Sze DM, Neilan BA. Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs. PLoS One 2012;7:e35953. [PMID: 22629306 DOI: 10.1371/journal.pone.0035953] [Cited by in Crossref: 47] [Cited by in F6Publishing: 38] [Article Influence: 4.7] [Reference Citation Analysis]
323 Sohrabi M, Saeedi M, Larijani B, Mahdavi M. Recent advances in biological activities of rhodium complexes: Their applications in drug discovery research. Eur J Med Chem 2021;216:113308. [PMID: 33713976 DOI: 10.1016/j.ejmech.2021.113308] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
324 Valanne A, Malmi P, Appelblom H, Niemelä P, Soukka T. A dual-step fluorescence resonance energy transfer-based quenching assay for screening of caspase-3 inhibitors. Analytical Biochemistry 2008;375:71-81. [DOI: 10.1016/j.ab.2007.12.032] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 1.1] [Reference Citation Analysis]
325 Roberts TC, Smith PA, Cirz RT, Romesberg FE. Structural and initial biological analysis of synthetic arylomycin A2. J Am Chem Soc 2007;129:15830-8. [PMID: 18052061 DOI: 10.1021/ja073340u] [Cited by in Crossref: 88] [Cited by in F6Publishing: 81] [Article Influence: 5.9] [Reference Citation Analysis]
326 Loughlin WA, Tyndall JDA, Glenn MP, Hill TA, Fairlie DP. Update 1 of: Beta-Strand Mimetics. Chem Rev 2010;110:PR32-69. [DOI: 10.1021/cr900395y] [Cited by in Crossref: 79] [Cited by in F6Publishing: 71] [Article Influence: 7.2] [Reference Citation Analysis]
327 Bhattacharya AK, Rana KC, Pannecouque C, De clercq E. An Efficient Synthesis of a Hydroxyethylamine (HEA) Isostere and Its α-Aminophosphonate and Phosphoramidate Derivatives as Potential Anti-HIV Agents. ChemMedChem 2012;7:1601-11. [DOI: 10.1002/cmdc.201200271] [Cited by in Crossref: 29] [Cited by in F6Publishing: 15] [Article Influence: 2.9] [Reference Citation Analysis]
328 Sośnicki JG. Regioselectivity, scope, and limitations of the addition of organolithium and allylmagnesium reagents to 1H-pyridine-2-thiones; access to 3,4-, 3,6-, and 5,6-dihydropyridine-2-thiones. Tetrahedron 2007;63:11862-77. [DOI: 10.1016/j.tet.2007.09.029] [Cited by in Crossref: 14] [Cited by in F6Publishing: 10] [Article Influence: 0.9] [Reference Citation Analysis]
329 Nunes A, Marto J, Gonçalves LM, Simões S, Félix R, Ascenso A, Lopes F, Ribeiro HM. Novel and Modified Neutrophil Elastase Inhibitor Loaded in Topical Formulations for Psoriasis Management. Pharmaceutics 2020;12:E358. [PMID: 32295247 DOI: 10.3390/pharmaceutics12040358] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 3.5] [Reference Citation Analysis]
330 Cutiño-avila B, Gil Pradas D, Aragón Abreu C, Fernández Marrero Y, Hernández de la Torre M, Salas Sarduy E, Chávez Planes MDLÁ, Guisán Seijas JM, Díaz Brito J, Del Monte-martínez A. Computer-aided design of bromelain and papain covalent immobilization. Rev Colomb Biotecnol 2014;16:19. [DOI: 10.15446/rev.colomb.biote.v16n1.44184] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
331 Ilies M, Banciu MD, Scozzafava A, Ilies MA, Caproiu MT, Supuran CT. Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating arylsulfonylureido and 5-dibenzo-suberenyl/suberyl moieties. Bioorganic & Medicinal Chemistry 2003;11:2227-39. [DOI: 10.1016/s0968-0896(03)00113-5] [Cited by in Crossref: 17] [Cited by in F6Publishing: 2] [Article Influence: 0.9] [Reference Citation Analysis]
332 Chen G, Xie Y, Zhang H, Wang P, Cheung H, Yang M, Sun H. A general colorimetric method for detecting protease activity based on peptide-induced gold nanoparticle aggregation. RSC Adv 2014;4:6560-3. [DOI: 10.1039/c3ra46493h] [Cited by in Crossref: 13] [Article Influence: 1.6] [Reference Citation Analysis]
333 Juers DH, Kim J, Matthews BW, Sieburth SM. Structural Analysis of Silanediols as Transition-State-Analogue Inhibitors of the Benchmark Metalloprotease Thermolysin ,. Biochemistry 2005;44:16524-8. [DOI: 10.1021/bi051346v] [Cited by in Crossref: 41] [Cited by in F6Publishing: 28] [Article Influence: 2.4] [Reference Citation Analysis]
334 Bigotti S, Meille SV, Volonterio A, Zanda M. Synthesis of Ψ[CH(RF)NH]Gly-peptides: The dramatic effect of a single fluorine atom on the diastereocontrol of the key aza-Michael reaction. Journal of Fluorine Chemistry 2008;129:767-74. [DOI: 10.1016/j.jfluchem.2008.06.018] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 0.9] [Reference Citation Analysis]
335 Moreira R, Santana AB, Iley J, Neres J, Douglas KT, Horton PN, Hursthouse MB. Design, Synthesis, and Enzymatic Evaluation of N -Acyloxyalkyl- and N1 -Oxazolidin-2,4-dion-5-yl-Substituted β-lactams as Novel Inhibitors of Human Leukocyte Elastase. J Med Chem 2005;48:4861-70. [DOI: 10.1021/jm0501331] [Cited by in Crossref: 29] [Cited by in F6Publishing: 22] [Article Influence: 1.7] [Reference Citation Analysis]
336 Volonterio A, Bellosta S, Bravo P, Canavesi M, Corradi E, Meille S, Monetti M, Moussier N, Zanda M. Solution/Solid-Phase Synthesis of Partially Modified Retro- and Retro-Inverso-ψ[NHCH(CF3)]-Peptidyl Hydroxamates and Their Evaluation as MMP-9 Inhibitors. Eur J Org Chem 2002;2002:428-38. [DOI: 10.1002/1099-0690(20022)2002:3<428::aid-ejoc428>3.0.co;2-j] [Cited by in Crossref: 18] [Article Influence: 0.9] [Reference Citation Analysis]
337 Perumal SK, Pratt RF. Synthesis and evaluation of ketophosph(on)ates as beta-lactamase inhibitors. J Org Chem 2006;71:4778-85. [PMID: 16776502 DOI: 10.1021/jo060364v] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 1.1] [Reference Citation Analysis]
338 Desai PV, Patny A, Gut J, Rosenthal PJ, Tekwani B, Srivastava A, Avery M. Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory. J Med Chem 2006;49:1576-84. [PMID: 16509575 DOI: 10.1021/jm0505765] [Cited by in Crossref: 52] [Cited by in F6Publishing: 46] [Article Influence: 3.3] [Reference Citation Analysis]
339 Glenn MP, Pattenden LK, Reid RC, Tyssen DP, Tyndall JD, Birch CJ, Fairlie DP. Beta-strand mimicking macrocyclic amino acids: templates for protease inhibitors with antiviral activity. J Med Chem 2002;45:371-81. [PMID: 11784141 DOI: 10.1021/jm010414i] [Cited by in Crossref: 58] [Cited by in F6Publishing: 42] [Article Influence: 2.9] [Reference Citation Analysis]
340 Chen C, Sieburth SM, Glekas A, Hewitt GW, Trainor GL, Erickson-viitanen S, Garber SS, Cordova B, Jeffry S, Klabe RM. Drug design with a new transition state analog of the hydrated carbonyl: silicon-based inhibitors of the HIV protease. Chemistry & Biology 2001;8:1161-6. [DOI: 10.1016/s1074-5521(01)00079-5] [Cited by in Crossref: 64] [Cited by in F6Publishing: 8] [Article Influence: 3.0] [Reference Citation Analysis]
341 Poyarkov A, Rocabayera X, Poyarkova S, Kukhar V. Influence of aromatic and aliphatic moieties on thrombin inhibitors potency. Open Biochem J 2008;2:143-9. [PMID: 19238188 DOI: 10.2174/1874091X00802010143] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
342 de Carvalho EM, Velloso MHR, Tinoco LW, Figueroa-villar JD. Formation of p-cresol:piperazine complex in solution monitored by spin–lattice relaxation times and pulsed field gradient NMR diffusion measurements. Journal of Magnetic Resonance 2003;164:197-204. [DOI: 10.1016/s1090-7807(03)00252-0] [Cited by in Crossref: 13] [Article Influence: 0.7] [Reference Citation Analysis]
343 Hernick M, Fierke CA. Catalytic mechanism and molecular recognition of E. coli UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase probed by mutagenesis. Biochemistry 2006;45:15240-8. [PMID: 17176046 DOI: 10.1021/bi061405k] [Cited by in Crossref: 23] [Cited by in F6Publishing: 20] [Article Influence: 1.6] [Reference Citation Analysis]
344 Iserloh U, Wu Y, Cumming J, Pan J, Wang L, Stamford A, Kennedy M, Kuvelkar R, Chen X, Parker E, Strickland C, Voigt J. Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Bioorganic & Medicinal Chemistry Letters 2008;18:414-7. [DOI: 10.1016/j.bmcl.2007.10.116] [Cited by in Crossref: 62] [Cited by in F6Publishing: 55] [Article Influence: 4.4] [Reference Citation Analysis]
345 Shang L, Fang H, Zhu H, Wang X, Wang Q, Mu J, Wang B, Kishioka S, Xu W. Design, synthesis and SAR studies of tripeptide analogs with the scaffold 3-phenylpropane-1,2-diamine as aminopeptidase N/CD13 inhibitors. Bioorganic & Medicinal Chemistry 2009;17:2775-84. [DOI: 10.1016/j.bmc.2009.02.034] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
346 Tyndall JD, Nall T, Fairlie DP. Proteases universally recognize beta strands in their active sites. Chem Rev 2005;105:973-99. [PMID: 15755082 DOI: 10.1021/cr040669e] [Cited by in Crossref: 295] [Cited by in F6Publishing: 268] [Article Influence: 17.4] [Reference Citation Analysis]
347 Qing G, Sun T, He Y, Wang F, Chen Z. Highly selective fluorescent recognition of phenyl amino alcohol based on ferrocenyl macrocyclic derivatives. Tetrahedron: Asymmetry 2009;20:575-83. [DOI: 10.1016/j.tetasy.2009.02.044] [Cited by in Crossref: 16] [Cited by in F6Publishing: 12] [Article Influence: 1.2] [Reference Citation Analysis]
348 Perni RB, Britt SD, Court JC, Courtney LF, Deininger DD, Farmer LJ, Gates CA, Harbeson SL, Kim JL, Landro JA, Levin RB, Luong Y, O'malley ET, Pitlik J, Rao B, Schairer WC, Thomson JA, Tung RD, Van Drie JH, Wei Y. Inhibitors of hepatitis C virus NS3·4A protease 1. Non-Charged tetrapeptide variants. Bioorganic & Medicinal Chemistry Letters 2003;13:4059-63. [DOI: 10.1016/j.bmcl.2003.08.050] [Cited by in Crossref: 31] [Cited by in F6Publishing: 23] [Article Influence: 1.6] [Reference Citation Analysis]
349 Nall TA, Chappell KJ, Stoermer MJ, Fang N, Tyndall JD, Young PR, Fairlie DP. Enzymatic Characterization and Homology Model of a Catalytically Active Recombinant West Nile Virus NS3 Protease. Journal of Biological Chemistry 2004;279:48535-42. [DOI: 10.1074/jbc.m406810200] [Cited by in Crossref: 96] [Cited by in F6Publishing: 31] [Article Influence: 5.3] [Reference Citation Analysis]
350 Volonterio A, Bravo P, Zanda M. Solution/solid-phase synthesis of partially modified retro- ψ [NHCH(CF 3 )]-peptidyl hydroxamates. Tetrahedron Letters 2001;42:3141-4. [DOI: 10.1016/s0040-4039(01)00375-6] [Cited by in Crossref: 20] [Article Influence: 1.0] [Reference Citation Analysis]
351 Hidaka K, Adachi M, Tsuda Y. Acquired Removability of Aspartic Protease Inhibitors by Direct Biotinylation. Bioconjug Chem 2019;30:1979-85. [PMID: 30990716 DOI: 10.1021/acs.bioconjchem.9b00195] [Reference Citation Analysis]
352 Sharma U, Suresh CG. Purification, crystallization and X-ray characterization of a Kunitz-type trypsin inhibitor protein from the seeds of chickpea (Cicer arietinum). Acta Crystallogr Sect F Struct Biol Cryst Commun 2011;67:714-7. [PMID: 21636920 DOI: 10.1107/S1744309111015338] [Cited by in Crossref: 3] [Article Influence: 0.3] [Reference Citation Analysis]
353 Zhang H, Wu ZY, Wang YZ, Zhou DD, Yang FQ, Li DQ. On-line immobilized trypsin microreactor for evaluating inhibitory activity of phenolic acids by capillary electrophoresis and molecular docking. Food Chem 2020;310:125823. [PMID: 31757489 DOI: 10.1016/j.foodchem.2019.125823] [Cited by in Crossref: 11] [Cited by in F6Publishing: 5] [Article Influence: 3.7] [Reference Citation Analysis]
354 Price S, Osbourn SE. Solid-Phase Synthesis of N- Formylhydroxylamines (Reverse/Retro-Hydroxamates). Org Lett 2005;7:3761-3. [DOI: 10.1021/ol0513995] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 0.4] [Reference Citation Analysis]
355 Butz K, Denk C, Fitscher B, Crnkovic-Mertens I, Ullmann A, Schröder CH, Hoppe-Seyler F. Peptide aptamers targeting the hepatitis B virus core protein: a new class of molecules with antiviral activity. Oncogene. 2001;20:6579-6586. [PMID: 11641783 DOI: 10.1038/sj.onc.1204805] [Cited by in Crossref: 59] [Cited by in F6Publishing: 48] [Article Influence: 2.8] [Reference Citation Analysis]
356 Viskupicova J, Danihelova M, Majekova M, Liptaj T, Sturdik E. Polyphenol fatty acid esters as serine protease inhibitors: a quantum-chemical QSAR analysis. J Enzyme Inhib Med Chem 2012;27:800-9. [PMID: 21981000 DOI: 10.3109/14756366.2010.616860] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.7] [Reference Citation Analysis]
357 Yin B, Dhal R, Maisonneuve V, Dujardin G. Asymmetric Access to Peptidyl β3-Aldehydes by Coupling ofN-Phthalyl α-Amino Acids with a Synthetic Heterocyclic β-Amino Aldehyde Precursor. Eur J Org Chem 2006;2006:3309-13. [DOI: 10.1002/ejoc.200600262] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
358 Gonçalves R, Mateus N, Pianet I, Laguerre M, de Freitas V. Mechanisms of Tannin-Induced Trypsin Inhibition: A Molecular Approach. Langmuir 2011;27:13122-9. [DOI: 10.1021/la202280c] [Cited by in Crossref: 51] [Cited by in F6Publishing: 43] [Article Influence: 4.6] [Reference Citation Analysis]
359 Löser R, Abbenante G, Madala PK, Halili M, Le GT, Fairlie DP. Noncovalent Tripeptidyl Benzyl- and Cyclohexyl-Amine Inhibitors of the Cysteine Protease Caspase-1. J Med Chem 2010;53:2651-5. [DOI: 10.1021/jm901790w] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 0.9] [Reference Citation Analysis]
360 McGrath WJ, Ding J, Didwania A, Sweet RM, Mangel WF. Crystallographic structure at 1.6-A resolution of the human adenovirus proteinase in a covalent complex with its 11-amino-acid peptide cofactor: insights on a new fold. Biochim Biophys Acta 2003;1648:1-11. [PMID: 12758141 DOI: 10.1016/s1570-9639(03)00024-4] [Cited by in Crossref: 24] [Cited by in F6Publishing: 13] [Article Influence: 1.3] [Reference Citation Analysis]
361 Kumar D, Gupta S. A quantitative structure–activity relationship study on some matrix metalloproteinase and collagenase inhibitors. Bioorganic & Medicinal Chemistry 2003;11:421-6. [DOI: 10.1016/s0968-0896(02)00438-8] [Cited by in Crossref: 24] [Cited by in F6Publishing: 2] [Article Influence: 1.3] [Reference Citation Analysis]
362 Zaghouani M, Bögeholz LAK, Mercier E, Wintermeyer W, Roche SP. Total synthesis of (±)-fumimycin and analogues for biological evaluation as peptide deformylase inhibitors. Tetrahedron 2019;75:3216-30. [PMID: 31555018 DOI: 10.1016/j.tet.2019.03.037] [Cited by in Crossref: 5] [Cited by in F6Publishing: 2] [Article Influence: 1.7] [Reference Citation Analysis]
363 Yadav DK, Khan F, Negi AS. Pharmacophore modeling, molecular docking, QSAR, and in silico ADMET studies of gallic acid derivatives for immunomodulatory activity. J Mol Model 2012;18:2513-25. [PMID: 22038459 DOI: 10.1007/s00894-011-1265-3] [Cited by in Crossref: 47] [Cited by in F6Publishing: 39] [Article Influence: 4.3] [Reference Citation Analysis]
364 Zhong J, Gan X, Alliston KR, Lai Z, Yu H, Groutas CS, Wong T, Groutas WC. Potential protease inhibitors based on a functionalized cyclic sulfamide scaffold. J Comb Chem 2004;6:556-63. [PMID: 15244417 DOI: 10.1021/cc030047r] [Cited by in Crossref: 20] [Cited by in F6Publishing: 14] [Article Influence: 1.2] [Reference Citation Analysis]
365 Chen D, Cai J, Yin J, Jiang J, Jing C, Zhu Y, Cheng J, Di Y, Zhang Y, Cao M, Li S, Peng Z, Hao X. Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors. Future Med Chem 2015;7:561-70. [PMID: 25921398 DOI: 10.4155/fmc.15.14] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 2.0] [Reference Citation Analysis]
366 Rudzińska M, Parodi A, Soond SM, Vinarov AZ, Korolev DO, Morozov AO, Daglioglu C, Tutar Y, Zamyatnin AA Jr. The Role of Cysteine Cathepsins in Cancer Progression and Drug Resistance. Int J Mol Sci 2019;20:E3602. [PMID: 31340550 DOI: 10.3390/ijms20143602] [Cited by in Crossref: 25] [Cited by in F6Publishing: 24] [Article Influence: 8.3] [Reference Citation Analysis]
367 Naqeebullah, Farina Y, Chan KM, Mun LK, Rajab NF, Ooi TC. Diorganotin(IV) derivatives of N-methyl p-fluorobenzo-hydroxamic acid: preparation, spectral characterization, X-ray diffraction studies and antitumor activity. Molecules 2013;18:8696-711. [PMID: 23881054 DOI: 10.3390/molecules18078696] [Cited by in Crossref: 14] [Cited by in F6Publishing: 7] [Article Influence: 1.6] [Reference Citation Analysis]
368 Wezenberg SJ, Escudero-adán EC, Benet-buchholz J, Kleij AW. Colorimetric Discrimination between Important Alkaloid Nuclei Mediated by a Bis-Salphen Chromophore. Org Lett 2008;10:3311-4. [DOI: 10.1021/ol801167r] [Cited by in Crossref: 53] [Cited by in F6Publishing: 40] [Article Influence: 3.8] [Reference Citation Analysis]
369 Kemnitzer W, Kuemmerle J, Jiang S, Zhang HZ, Sirisoma N, Kasibhatla S, Crogan-Grundy C, Tseng B, Drewe J, Cai SX. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions. Bioorg Med Chem Lett 2008;18:6259-64. [PMID: 18952423 DOI: 10.1016/j.bmcl.2008.09.110] [Cited by in Crossref: 55] [Cited by in F6Publishing: 44] [Article Influence: 3.9] [Reference Citation Analysis]
370 Akaberi D, Chinthakindi PK, Båhlström A, Palanisamy N, Sandström A, Lundkvist Å, Lennerstrand J. Identification of a C2-symmetric diol based human immunodeficiency virus protease inhibitor targeting Zika virus NS2B-NS3 protease. J Biomol Struct Dyn 2020;38:5526-36. [PMID: 31880199 DOI: 10.1080/07391102.2019.1704882] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
371 Jiang Z, Zhou Y. Using Bioinformatics for Drug Target Identification from the Genome: . American Journal of PharmacoGenomics 2005;5:387-96. [DOI: 10.2165/00129785-200505060-00005] [Cited by in Crossref: 20] [Cited by in F6Publishing: 12] [Article Influence: 1.2] [Reference Citation Analysis]
372 Jain R, Sundram A, Lopez S, Neckermann G, Wu C, Hackbarth C, Chen D, Wang W, Ryder N, Weidmann B, Patel D, Trias J, White R, Yuan Z. α-Substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents. Bioorganic & Medicinal Chemistry Letters 2003;13:4223-8. [DOI: 10.1016/j.bmcl.2003.07.020] [Cited by in Crossref: 24] [Cited by in F6Publishing: 17] [Article Influence: 1.3] [Reference Citation Analysis]
373 Sova M, Babič A, Pečar S, Gobec S. Microwave-assisted synthesis of hydroxyethylamine dipeptide isosteres. Tetrahedron 2007;63:141-7. [DOI: 10.1016/j.tet.2006.10.033] [Cited by in Crossref: 11] [Cited by in F6Publishing: 7] [Article Influence: 0.7] [Reference Citation Analysis]
374 Thomas DA, Francis P, Smith C, Ratcliffe S, Ede NJ, Kay C, Wayne G, Martin SL, Moore K, Amour A, Hooper NM. A broad-spectrum fluorescence-based peptide library for the rapid identification of protease substrates. Proteomics 2006;6:2112-20. [DOI: 10.1002/pmic.200500153] [Cited by in Crossref: 39] [Cited by in F6Publishing: 35] [Article Influence: 2.4] [Reference Citation Analysis]
375 Choi Y, Lee J, Kim K, Kim H, Sommer P, Song R. Fluorogenic assay and live cell imaging of HIV-1 protease activity using acid-stable quantum dot–peptide complex. Chem Commun 2010;46:9146. [DOI: 10.1039/c0cc02702b] [Cited by in Crossref: 29] [Cited by in F6Publishing: 23] [Article Influence: 2.4] [Reference Citation Analysis]
376 Citron M. Alzheimer's disease: strategies for disease modification. Nat Rev Drug Discov 2010;9:387-98. [DOI: 10.1038/nrd2896] [Cited by in Crossref: 718] [Cited by in F6Publishing: 687] [Article Influence: 59.8] [Reference Citation Analysis]
377 Andújar-sánchez M, Cámara-artigas A, Jara-pérez V. A calorimetric study of the binding of lisinopril, enalaprilat and captopril to angiotensin-converting enzyme. Biophysical Chemistry 2004;111:183-9. [DOI: 10.1016/j.bpc.2004.05.011] [Cited by in Crossref: 39] [Cited by in F6Publishing: 34] [Article Influence: 2.2] [Reference Citation Analysis]
378 Kaysser L. Built to bind: biosynthetic strategies for the formation of small-molecule protease inhibitors. Nat Prod Rep 2019;36:1654-86. [DOI: 10.1039/c8np00095f] [Cited by in Crossref: 10] [Cited by in F6Publishing: 5] [Article Influence: 3.3] [Reference Citation Analysis]
379 Karvinen J, Laitala V, Mäkinen M, Mulari O, Tamminen J, Hermonen J, Hurskainen P, Hemmilä I. Fluorescence Quenching-Based Assays for Hydrolyzing Enzymes. Application of Time-Resolved Fluorometry in Assays for Caspase, Helicase, and Phosphatase. Anal Chem 2004;76:1429-36. [DOI: 10.1021/ac030234b] [Cited by in Crossref: 57] [Cited by in F6Publishing: 49] [Article Influence: 3.2] [Reference Citation Analysis]
380 You X, Li Y, Li B, Ma J. Gold nanoclusters-based chemiluminescence resonance energy transfer method for sensitive and label-free detection of trypsin. Talanta 2016;147:63-8. [PMID: 26592577 DOI: 10.1016/j.talanta.2015.09.033] [Cited by in Crossref: 28] [Cited by in F6Publishing: 25] [Article Influence: 4.0] [Reference Citation Analysis]
381 Gupta S, Kumar D, Kumaran S. A quantitative structure–activity relationship study of hydroxamate matrix metalloproteinase inhibitors derived from funtionalized 4-aminoprolines. Bioorganic & Medicinal Chemistry 2003;11:1975-81. [DOI: 10.1016/s0968-0896(03)00069-5] [Cited by in Crossref: 16] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
382 Sova M, Cadez G, Turk S, Majce V, Polanc S, Batson S, Lloyd AJ, Roper DI, Fishwick CW, Gobec S. Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB). Bioorg Med Chem Lett 2009;19:1376-9. [PMID: 19196510 DOI: 10.1016/j.bmcl.2009.01.034] [Cited by in Crossref: 31] [Cited by in F6Publishing: 27] [Article Influence: 2.4] [Reference Citation Analysis]
383 Hill TA, Shepherd NE, Diness F, Fairlie DP. Constraining cyclic peptides to mimic protein structure motifs. Angew Chem Int Ed Engl 2014;53:13020-41. [PMID: 25287434 DOI: 10.1002/anie.201401058] [Cited by in Crossref: 260] [Cited by in F6Publishing: 215] [Article Influence: 32.5] [Reference Citation Analysis]
384 Mangiatordi GF, Guzzo T, Rossano EC, Trisciuzzi D, Alberga D, Fasciglione G, Coletta M, Topai A, Nicolotti O. Design, Synthesis, and Biological Evaluation of Tetrahydro-β-carboline Derivatives as Selective Sub-Nanomolar Gelatinase Inhibitors. ChemMedChem 2018;13:1343-52. [PMID: 29893479 DOI: 10.1002/cmdc.201800237] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
385 Ehmke V, Kilchmann F, Heindl C, Cui K, Huang J, Schirmeister T, Diederich F. Peptidomimetic nitriles as selective inhibitors for the malarial cysteine protease falcipain-2. Med Chem Commun 2011;2:800. [DOI: 10.1039/c1md00115a] [Cited by in Crossref: 20] [Cited by in F6Publishing: 16] [Article Influence: 1.8] [Reference Citation Analysis]
386 Ranasinghe SL, McManus DP. Protease Inhibitors of Parasitic Flukes: Emerging Roles in Parasite Survival and Immune Defence. Trends Parasitol 2017;33:400-13. [PMID: 28089171 DOI: 10.1016/j.pt.2016.12.013] [Cited by in Crossref: 18] [Cited by in F6Publishing: 15] [Article Influence: 3.6] [Reference Citation Analysis]
387 Karaffa J, Lindsay KB, Skrydstrup T. Expanding the Scope of the Acyl-Type Radical Addition Reactions Promoted by SmI 2. J Org Chem 2006;71:8219-26. [DOI: 10.1021/jo061299s] [Cited by in Crossref: 22] [Cited by in F6Publishing: 17] [Article Influence: 1.4] [Reference Citation Analysis]
388 Aubry S, Sasaki K, Eloy L, Aubert G, Retailleau P, Cresteil T, Crich D. Exploring the potential of the β-thiolactones in bioorganic chemistry. Org Biomol Chem 2011;9:7134. [DOI: 10.1039/c1ob05967j] [Cited by in Crossref: 16] [Cited by in F6Publishing: 8] [Article Influence: 1.5] [Reference Citation Analysis]
389 Ngoc Tam NT, Magueur G, Ourévitch M, Crousse B, Bégué J, Bonnet-delpon D. Analogues of Key Precursors of Aspartyl Protease Inhibitors:  Synthesis of Trifluoromethyl Amino Epoxides. J Org Chem 2005;70:699-702. [DOI: 10.1021/jo0485233] [Cited by in Crossref: 46] [Cited by in F6Publishing: 39] [Article Influence: 2.6] [Reference Citation Analysis]
390 Chaudhari SR, Suryaprakash N. Probing acid–amide intermolecular hydrogen bonding by NMR spectroscopy and DFT calculations. Journal of Molecular Structure 2012;1016:163-8. [DOI: 10.1016/j.molstruc.2012.02.058] [Cited by in Crossref: 14] [Cited by in F6Publishing: 7] [Article Influence: 1.4] [Reference Citation Analysis]
391 Ersmark K, Del valle J, Hanessian S. Chemistry and Biology of the Aeruginosin Family of Serine Protease Inhibitors. Angew Chem Int Ed 2008;47:1202-23. [DOI: 10.1002/anie.200605219] [Cited by in Crossref: 137] [Cited by in F6Publishing: 111] [Article Influence: 9.8] [Reference Citation Analysis]
392 Tung CH. Fluorescent peptide probes for in vivo diagnostic imaging. Biopolymers. 2004;76:391-403. [PMID: 15389488 DOI: 10.1002/bip.20139] [Cited by in Crossref: 140] [Cited by in F6Publishing: 128] [Article Influence: 8.2] [Reference Citation Analysis]
393 Citron M. ?-secretase as a target for the treatment of Alzheimer's disease. J Neurosci Res 2002;70:373-9. [DOI: 10.1002/jnr.10393] [Cited by in Crossref: 50] [Cited by in F6Publishing: 47] [Article Influence: 2.5] [Reference Citation Analysis]
394 Kong D, Bhatt MP, Lee S, Kim Y, Ha K. Characterization of TAMRA- and biotin-conjugated peptide arrays for on-chip matrix metalloproteinase activity assay. BioChip J 2012;6:307-13. [DOI: 10.1007/s13206-012-6401-3] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
395 You C, Arvizo RR, Rotello VM. Regulation of α-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles. Chem Commun 2006. [DOI: 10.1039/b605508g] [Cited by in Crossref: 26] [Cited by in F6Publishing: 6] [Article Influence: 1.6] [Reference Citation Analysis]
396 Belen’kii L, Gramenitskaya V. The Literature of Heterocyclic Chemistry, Part VIII, 1999–2001. Elsevier; 2004. pp. 1-83. [DOI: 10.1016/s0065-2725(04)87001-6] [Cited by in Crossref: 14] [Article Influence: 0.8] [Reference Citation Analysis]
397 Peng SX. Separation and identification methods for metalloproteinase inhibitors. J Chromatogr B Biomed Sci Appl 2001;764:59-80. [PMID: 11817044 DOI: 10.1016/s0378-4347(01)00316-4] [Cited by in Crossref: 6] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
398 El Mansouri AE, Oubella A, Dânoun K, Ahmad M, Neyts J, Jochmans D, Snoeck R, Andrei G, Morjani H, Zahouily M, Lazrek HB. Discovery of novel furo[2,3-d]pyrimidin-2-one-1,3,4-oxadiazole hybrid derivatives as dual antiviral and anticancer agents that induce apoptosis. Arch Pharm (Weinheim) 2021;:e2100146. [PMID: 34128255 DOI: 10.1002/ardp.202100146] [Reference Citation Analysis]
399 Hernick M. Fluorescence-Based Methods to Assay Inhibitors of Lipopolysaccharide Synthesis. In: Holst O, editor. Microbial Toxins. Totowa: Humana Press; 2011. pp. 123-33. [DOI: 10.1007/978-1-61779-102-4_11] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
400 Gazal S, Masterson L, Barany G. Facile solid-phase synthesis of C-terminal peptide aldehydes and hydroxamates from a common Backbone Amide-Linked (BAL) intermediate*†: Synthesis of peptide aldehydes and hydroxamates. The Journal of Peptide Research 2005;66:324-32. [DOI: 10.1111/j.1399-3011.2005.00311.x] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.6] [Reference Citation Analysis]
401 Brouwer AJ, Ceylan T, Jonker AM, van der Linden T, Liskamp RM. Synthesis and biological evaluation of novel irreversible serine protease inhibitors using amino acid based sulfonyl fluorides as an electrophilic trap. Bioorg Med Chem 2011;19:2397-406. [PMID: 21421320 DOI: 10.1016/j.bmc.2011.02.014] [Cited by in Crossref: 29] [Cited by in F6Publishing: 25] [Article Influence: 2.6] [Reference Citation Analysis]
402 Vassiliou S, Tzouma E. Mapping the Pathway toward Thiophosphinic Pseudopeptides. Synthesis of Suitably Protected PG-Phe-Ψ[P(S)(OX)CH 2 ]-Gly-OY Analogues as Thiophosphinyl Dipeptide Isosters (TDI), a Comparative Study for Selective Deprotection and Further Elongation. J Org Chem 2013;78:10069-76. [DOI: 10.1021/jo401084v] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
403 Choi Y, Cho Y, Kim M, Grailhe R, Song R. Fluorogenic Quantum Dot-Gold Nanoparticle Assembly for Beta Secretase Inhibitor Screening in Live Cell. Anal Chem 2012;84:8595-601. [DOI: 10.1021/ac301574b] [Cited by in Crossref: 47] [Cited by in F6Publishing: 42] [Article Influence: 4.7] [Reference Citation Analysis]
404 Zhou J, Ma C, Zhen S, Cao M, Zeller FJ, Hsam SLK, Yan Y. Identification of drought stress related proteins from 1Sl(1B) chromosome substitution line of wheat variety Chinese Spring. Bot Stud 2016;57:20. [PMID: 28597430 DOI: 10.1186/s40529-016-0134-x] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 2.0] [Reference Citation Analysis]
405 Xiao K, Li X, Li J, Ma L, Hu B, Yu H, Fu Y, Wang R, Ma Z, Qiu B, Li J, Hu D, Wang X, Shen J. Design, synthesis, and evaluation of Leu∗Ala hydroxyethylene-based non-peptide β-secretase (BACE) inhibitors. Bioorganic & Medicinal Chemistry 2006;14:4535-51. [DOI: 10.1016/j.bmc.2006.02.024] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 0.8] [Reference Citation Analysis]
406 Rickert KW, Kelley P, Byrne NJ, Diehl RE, Hall DL, Montalvo AM, Reid JC, Shipman JM, Thomas BW, Munshi SK, Darke PL, Su HP. Structure of human prostasin, a target for the regulation of hypertension. J Biol Chem 2008;283:34864-72. [PMID: 18922802 DOI: 10.1074/jbc.M805262200] [Cited by in Crossref: 29] [Cited by in F6Publishing: 19] [Article Influence: 2.1] [Reference Citation Analysis]
407 Cai J, Jamieson C, Moir J, Rankovic Z. Cathepsin K inhibitors, 2000 – 2004. Expert Opinion on Therapeutic Patents 2005;15:33-48. [DOI: 10.1517/13543776.15.1.33] [Cited by in Crossref: 16] [Cited by in F6Publishing: 14] [Article Influence: 0.9] [Reference Citation Analysis]
408 Macdonald SJ, Dowle MD, Harrison LA, Shah P, Johnson MR, Inglis GG, Clarke GD, Smith RA, Humphreys D, Molloy CR, Amour A, Dixon M, Murkitt G, Godward RE, Padfield T, Skarzynski T, Singh OM, Kumar KA, Fleetwood G, Hodgson ST, Hardy GW, Finch H. The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate. Bioorg Med Chem Lett 2001;11:895-8. [PMID: 11294386 DOI: 10.1016/s0960-894x(01)00078-6] [Cited by in Crossref: 34] [Cited by in F6Publishing: 15] [Article Influence: 1.6] [Reference Citation Analysis]
409 Bihel F, Quéléver G, Lelouard H, Petit A, Alvès da Costa C, Pourquié O, Checler F, Thellend A, Pierre P, Kraus J. Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new β-amyloid peptide production inhibitors and their activities on various classes of protease. Bioorganic & Medicinal Chemistry 2003;11:3141-52. [DOI: 10.1016/s0968-0896(03)00235-9] [Cited by in Crossref: 33] [Cited by in F6Publishing: 7] [Article Influence: 1.7] [Reference Citation Analysis]
410 Kang C, Gayen S, Wang W, Severin R, Chen AS, Lim HA, Chia CS, Schüller A, Doan DN, Poulsen A, Hill J, Vasudevan SG, Keller TH. Exploring the binding of peptidic West Nile virus NS2B-NS3 protease inhibitors by NMR. Antiviral Res 2013;97:137-44. [PMID: 23211132 DOI: 10.1016/j.antiviral.2012.11.008] [Cited by in Crossref: 25] [Cited by in F6Publishing: 25] [Article Influence: 2.5] [Reference Citation Analysis]
411 Marcq V, Mirand C, Decarme M, Emonard H, Hornebeck W. MMPs inhibitors: new succinylhydroxamates with selective inhibition of MMP-2 over MMP-3. Bioorganic & Medicinal Chemistry Letters 2003;13:2843-6. [DOI: 10.1016/s0960-894x(03)00590-0] [Cited by in Crossref: 17] [Cited by in F6Publishing: 3] [Article Influence: 0.9] [Reference Citation Analysis]
412 Kemnitzer W, Drewe J, Jiang S, Zhang H, Zhao J, Crogan-Grundy C, Xu L, Lamothe S, Gourdeau H, Denis R, Tseng B, Kasibhatla S, Cai SX. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 3. Structure-activity relationships of fused rings at the 7,8-positions. J Med Chem 2007;50:2858-64. [PMID: 17497765 DOI: 10.1021/jm070216c] [Cited by in Crossref: 136] [Cited by in F6Publishing: 93] [Article Influence: 9.1] [Reference Citation Analysis]
413 Leung-Toung R, Wodzinska J, Li W, Lowrie J, Kukreja R, Desilets D, Karimian K, Tam TF. 1,2,4-thiadiazole: a novel Cathepsin B inhibitor. Bioorg Med Chem 2003;11:5529-37. [PMID: 14642597 DOI: 10.1016/j.bmc.2003.09.040] [Cited by in Crossref: 52] [Cited by in F6Publishing: 39] [Article Influence: 2.9] [Reference Citation Analysis]
414 Modarresi-alam AR, Khamooshi F, Rostamizadeh M, Keykha H, Nasrollahzadeh M, Bijanzadeh H, Kleinpeter E. Dynamic 1H NMR spectroscopic study of the restricted SN rotation in aryl-N-(arylsulfonyl)-N-(triphenylphosphoranylidene)imidocarbamates. Journal of Molecular Structure 2007;841:61-6. [DOI: 10.1016/j.molstruc.2006.11.058] [Cited by in Crossref: 50] [Cited by in F6Publishing: 21] [Article Influence: 3.3] [Reference Citation Analysis]
415 Karstad R, Isaksen G, Wynendaele E, Guttormsen Y, De Spiegeleer B, Brandsdal B, Svendsen JS, Svenson J. Targeting the S1 and S3 Subsite of Trypsin with Unnatural Cationic Amino Acids Generates Antimicrobial Peptides with Potential for Oral Administration. J Med Chem 2012;55:6294-305. [DOI: 10.1021/jm3002058] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 2.3] [Reference Citation Analysis]
416 Iyer A, Fenning A, Lim J, Le GT, Reid RC, Halili MA, Fairlie DP, Brown L. Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. Br J Pharmacol 2010;159:1408-17. [PMID: 20180942 DOI: 10.1111/j.1476-5381.2010.00637.x] [Cited by in Crossref: 92] [Cited by in F6Publishing: 85] [Article Influence: 7.7] [Reference Citation Analysis]
417 Zhong J, Gan X, Alliston KR, Groutas WC. Design, synthesis, and in vitro evaluation of inhibitors of human leukocyte elastase based on a functionalized cyclic sulfamide scaffold. Bioorg Med Chem 2004;12:589-93. [PMID: 14738969 DOI: 10.1016/j.bmc.2003.10.059] [Cited by in Crossref: 24] [Cited by in F6Publishing: 17] [Article Influence: 1.3] [Reference Citation Analysis]
418 Citron M. Beta-secretase inhibition for the treatment of Alzheimer's disease--promise and challenge. Trends Pharmacol Sci 2004;25:92-7. [PMID: 15102495 DOI: 10.1016/j.tips.2003.12.004] [Cited by in Crossref: 141] [Cited by in F6Publishing: 137] [Article Influence: 7.8] [Reference Citation Analysis]
419 Podstawka E, Olszewski TK, Boduszek B, Proniewicz LM. Adsorbed States of Phosphonate Derivatives of N -Heterocyclic Aromatic Compounds, Imidazole, Thiazole, and Pyridine on Colloidal Silver: Comparison with a Silver Electrode. J Phys Chem B 2009;113:12013-8. [DOI: 10.1021/jp9050116] [Cited by in Crossref: 18] [Cited by in F6Publishing: 14] [Article Influence: 1.4] [Reference Citation Analysis]
420 Scozzafava A, Supuran CT. Carbonic Anhydrase and Matrix Metalloproteinase Inhibitors:  Sulfonylated Amino Acid Hydroxamates with MMP Inhibitory Properties Act as Efficient Inhibitors of CA Isozymes I, II, and IV, and N -Hydroxysulfonamides Inhibit Both These Zinc Enzymes. J Med Chem 2000;43:3677-87. [DOI: 10.1021/jm000027t] [Cited by in Crossref: 168] [Cited by in F6Publishing: 142] [Article Influence: 7.6] [Reference Citation Analysis]
421 Guan R, Roychowdhury A, Ember B, Kumar S, Boons GJ, Mariuzza RA. Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc Natl Acad Sci U S A 2004;101:17168-73. [PMID: 15572450 DOI: 10.1073/pnas.0407856101] [Cited by in Crossref: 94] [Cited by in F6Publishing: 94] [Article Influence: 5.2] [Reference Citation Analysis]
422 Gerona-Navarro G, Pérez de Vega MJ, García-López MT, Andrei G, Snoeck R, Balzarini J, De Clercq E, González-Muñiz R. Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine. Bioorg Med Chem Lett 2004;14:2253-6. [PMID: 15081019 DOI: 10.1016/j.bmcl.2004.02.010] [Cited by in Crossref: 48] [Cited by in F6Publishing: 32] [Article Influence: 2.7] [Reference Citation Analysis]
423 Rauh D, Klebe G, Stürzebecher J, Stubbs MT. ZZ Made EZ: Influence of Inhibitor Configuration on Enzyme Selectivity. Journal of Molecular Biology 2003;330:761-70. [DOI: 10.1016/s0022-2836(03)00617-x] [Cited by in Crossref: 16] [Cited by in F6Publishing: 4] [Article Influence: 0.8] [Reference Citation Analysis]
424 Aureggi V, Ehmke V, Wieland J, Schweizer WB, Bernet B, Bur D, Meyer S, Rottmann M, Freymond C, Brun R, Breit B, Diederich F. Potent inhibitors of malarial aspartic proteases, the plasmepsins, by hydroformylation of substituted 7-azanorbornenes. Chemistry 2013;19:155-64. [PMID: 23161835 DOI: 10.1002/chem.201202941] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 1.3] [Reference Citation Analysis]
425 Hamada Y, Kiso Y. New directions for protease inhibitors directed drug discovery. Biopolymers 2016;106:563-79. [PMID: 26584340 DOI: 10.1002/bip.22780] [Cited by in Crossref: 23] [Cited by in F6Publishing: 17] [Article Influence: 4.6] [Reference Citation Analysis]
426 Gupta SP. QSAR Studies on Hydroxamic Acids: A Fascinating Family of Chemicals with a Wide Spectrum of Activities. Chem Rev 2015;115:6427-90. [DOI: 10.1021/cr500483r] [Cited by in Crossref: 31] [Cited by in F6Publishing: 20] [Article Influence: 4.4] [Reference Citation Analysis]
427 Hu X, Balaz S, Shelver WH. A practical approach to docking of zinc metalloproteinase inhibitors. Journal of Molecular Graphics and Modelling 2004;22:293-307. [DOI: 10.1016/j.jmgm.2003.11.002] [Cited by in Crossref: 75] [Cited by in F6Publishing: 62] [Article Influence: 4.2] [Reference Citation Analysis]
428 Cerminara I, Chiummiento L, Funicello M, Guarnaccio A, Lupattelli P. Heterocycles in peptidomimetics and pseudopeptides: design and synthesis. Pharmaceuticals (Basel) 2012;5:297-316. [PMID: 24281380 DOI: 10.3390/ph5030297] [Cited by in Crossref: 16] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
429 Hanessian S, Ersmark K, Wang X, Del Valle JR, Blomberg N, Xue Y, Fjellström O. Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin. Bioorganic & Medicinal Chemistry Letters 2007;17:3480-5. [DOI: 10.1016/j.bmcl.2007.03.075] [Cited by in Crossref: 25] [Cited by in F6Publishing: 20] [Article Influence: 1.7] [Reference Citation Analysis]
430 Jaffrelot Inizan T, Célerse F, Adjoua O, El Ahdab D, Jolly LH, Liu C, Ren P, Montes M, Lagarde N, Lagardère L, Monmarché P, Piquemal JP. High-resolution mining of the SARS-CoV-2 main protease conformational space: supercomputer-driven unsupervised adaptive sampling. Chem Sci 2021;12:4889-907. [PMID: 34168762 DOI: 10.1039/d1sc00145k] [Cited by in Crossref: 9] [Cited by in F6Publishing: 5] [Article Influence: 9.0] [Reference Citation Analysis]
431 Supuran CT, Scozzafava A, Mastrolorenzo A. Bacterial proteases: current therapeutic use and future prospects for the development of new antibiotics. Expert Opinion on Therapeutic Patents 2005;11:221-59. [DOI: 10.1517/13543776.11.2.221] [Cited by in Crossref: 89] [Cited by in F6Publishing: 64] [Article Influence: 5.2] [Reference Citation Analysis]
432 Hanessian S, Sailes H, Therrien E. Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitors. Tetrahedron 2003;59:7047-56. [DOI: 10.1016/s0040-4020(03)00919-0] [Cited by in Crossref: 85] [Article Influence: 4.5] [Reference Citation Analysis]
433 Skálová T, Hašek J, Dohnálek J, Petroková H, Buchtelová E, Dušková J, Souček M, Majer P, Uhlíková T, Konvalinka J. An Ethylenamine Inhibitor Binds Tightly to Both Wild Type and Mutant HIV-1 Proteases. Structure and Energy Study. J Med Chem 2003;46:1636-44. [DOI: 10.1021/jm021079g] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 0.5] [Reference Citation Analysis]
434 He M, Yang N, Sun C, Yao X, Yang M. Modification and biological evaluation of novel 4-hydroxy-pyrone derivatives as non-peptidic HIV-1 protease inhibitors. Med Chem Res 2011;20:200-9. [DOI: 10.1007/s00044-010-9307-4] [Cited by in Crossref: 25] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
435 Tillekeratne LM, Sherette A, Grossman P, Hupe L, Hupe D, Hudson RA. Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett 2001;11:2763-7. [PMID: 11591519 DOI: 10.1016/s0960-894x(01)00577-7] [Cited by in Crossref: 38] [Cited by in F6Publishing: 6] [Article Influence: 1.8] [Reference Citation Analysis]
436 Hu J, Liu F, Feng N, Ju H. Selenium-isotopic signature toward mass spectrometric identification and enzyme activity assay. Anal Chim Acta 2019;1064:1-10. [PMID: 30982506 DOI: 10.1016/j.aca.2019.03.045] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
437 Yin H, Hamilton AD. Strategien zur Modulation von Protein-Protein-Wechselwirkungen mit synthetischen Substanzen. Angew Chem 2005;117:4200-35. [DOI: 10.1002/ange.200461786] [Cited by in Crossref: 82] [Cited by in F6Publishing: 64] [Article Influence: 4.8] [Reference Citation Analysis]
438 Ganesh Kumar M, Mali SM, Raja KMP, Gopi HN. Design of Stable β-Hairpin Mimetics through Backbone Disulfide Bonds. Org Lett 2015;17:230-3. [DOI: 10.1021/ol503310r] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.0] [Reference Citation Analysis]
439 Burt ET. Current approaches to the treatment of Candida albicans infections. Expert Opinion on Therapeutic Patents 2005;11:269-82. [DOI: 10.1517/13543776.11.2.269] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
440 Zhang H, Cao J, Wu S, Wang Y. Mechanism of gold nanoparticles-induced trypsin inhibition: a multi-technique approach. Mol Biol Rep 2014;41:4911-8. [DOI: 10.1007/s11033-014-3357-5] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 1.3] [Reference Citation Analysis]
441 Wang R, Wu J, Deng X, Liu D, Yan Y. Drought-responsive protein identification in developing grains of a wheat–Haynaldia villosa 6VS/6AL translocation line. Crop Pasture Sci 2018;69:1182. [DOI: 10.1071/cp18303] [Cited by in Crossref: 5] [Cited by in F6Publishing: 1] [Article Influence: 1.3] [Reference Citation Analysis]
442 Coburn CA, Stachel SJ, Li Y, Rush DM, Steele TG, Chen-dodson E, Holloway MK, Xu M, Huang Q, Lai M, Dimuzio J, Crouthamel M, Shi X, Sardana V, Chen Z, Munshi S, Kuo L, Makara GM, Annis DA, Tadikonda PK, Nash HM, Vacca JP, Wang T. Identification of a Small Molecule Nonpeptide Active Site β-Secretase Inhibitor That Displays a Nontraditional Binding Mode for Aspartyl Proteases. J Med Chem 2004;47:6117-9. [DOI: 10.1021/jm049388p] [Cited by in Crossref: 88] [Cited by in F6Publishing: 83] [Article Influence: 4.9] [Reference Citation Analysis]
443 Arenas M, Villaverde MC, Sussman F. Prediction and analysis of binding affinities for chemically diverse HIV-1 PR inhibitors by the modified SAFE_p approach. J Comput Chem 2009;30:1229-40. [PMID: 18988271 DOI: 10.1002/jcc.21147] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 0.2] [Reference Citation Analysis]
444 Bouzide A, Sauvé G, Sévigny G, Yelle J. 1,2,5,6-Tetra- O -benzyl- d -mannitol derivatives as novel HIV protease inhibitors. Bioorganic & Medicinal Chemistry Letters 2003;13:3601-5. [DOI: 10.1016/s0960-894x(03)00677-2] [Cited by in Crossref: 12] [Cited by in F6Publishing: 1] [Article Influence: 0.6] [Reference Citation Analysis]
445 Koparir P, Karaarslan M, Orek C, Koparir M. Synthesis and Characterization of Novel Chiral (1 R ,2 R )-1,2-Bis[5-(Aminomethylphospinic Acid)-1,3,4-Thiadiazol-2-YL]Ethane-1,2-Diols. Phosphorus, Sulfur, and Silicon and the Related Elements 2012;187:864-70. [DOI: 10.1080/10426507.2011.636412] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
446 Shirasaki Y, Miyashita H, Yamaguchi M. Exploration of orally available calpain inhibitors. Part 3: Dipeptidyl alpha-ketoamide derivatives containing pyridine moiety. Bioorg Med Chem 2006;14:5691-8. [PMID: 16651001 DOI: 10.1016/j.bmc.2006.04.013] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 0.9] [Reference Citation Analysis]
447 Kokotos CG, Baskakis C, Kokotos G. Synthesis of Medicinally Interesting Polyfluoro Ketones via Perfluoroalkyl Lithium Reagents. J Org Chem 2008;73:8623-6. [DOI: 10.1021/jo801469x] [Cited by in Crossref: 35] [Cited by in F6Publishing: 23] [Article Influence: 2.5] [Reference Citation Analysis]
448 Das BC, Anguiano J, Mahalingam SM. Design and synthesis of α-aminonitrile-functionalized novel retinoids. Tetrahedron Letters 2009;50:5670-2. [DOI: 10.1016/j.tetlet.2009.07.119] [Cited by in Crossref: 9] [Article Influence: 0.7] [Reference Citation Analysis]
449 Salisbury CM, Maly DJ, Ellman JA. Peptide Microarrays for the Determination of Protease Substrate Specificity. J Am Chem Soc 2002;124:14868-70. [DOI: 10.1021/ja027477q] [Cited by in Crossref: 219] [Cited by in F6Publishing: 185] [Article Influence: 11.0] [Reference Citation Analysis]
450 Kim SH, Lee YH, Jung SY, Kim HJ, Jin C, Lee YS. Synthesis of chromone carboxamide derivatives with antioxidative and calpain inhibitory properties. Eur J Med Chem 2011;46:1721-8. [PMID: 21397369 DOI: 10.1016/j.ejmech.2011.02.025] [Cited by in Crossref: 14] [Cited by in F6Publishing: 7] [Article Influence: 1.3] [Reference Citation Analysis]
451 Nar H, Bauer M, Schmid A, Stassen JM, Wienen W, Priepke HW, Kauffmann IK, Ries UJ, Hauel NH. Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors. Structure 2001;9:29-37. [PMID: 11342132 DOI: 10.1016/s0969-2126(00)00551-7] [Cited by in Crossref: 66] [Cited by in F6Publishing: 18] [Article Influence: 3.1] [Reference Citation Analysis]
452 Mugherli L, Burchak ON, Chatelain F, Balakirev MY. Fluorogenic ester substrates to assess proteolytic activity. Bioorg Med Chem Lett 2006;16:4488-91. [PMID: 16806926 DOI: 10.1016/j.bmcl.2006.06.037] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 1.2] [Reference Citation Analysis]
453 Singh J, Shah R, Singh D. Targeting mast cells: Uncovering prolific therapeutic role in myriad diseases. Int Immunopharmacol 2016;40:362-84. [PMID: 27694038 DOI: 10.1016/j.intimp.2016.09.019] [Cited by in Crossref: 21] [Cited by in F6Publishing: 19] [Article Influence: 3.5] [Reference Citation Analysis]
454 Vu QN, Young R, Sudhakar HK, Gao T, Huang T, Tan YS, Lau YH. Cyclisation strategies for stabilising peptides with irregular conformations. RSC Med Chem 2021;12:887-901. [PMID: 34263169 DOI: 10.1039/d1md00098e] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
455 Colletti SL, Myers RW, Darkin-Rattray SJ, Gurnett AM, Dulski PM, Galuska S, Allocco JJ, Ayer MB, Li C, Lim J, Crumley TM, Cannova C, Schmatz DM, Wyvratt MJ, Fisher MH, Meinke PT. Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1. Bioorg Med Chem Lett 2001;11:107-11. [PMID: 11206438 DOI: 10.1016/s0960-894x(00)00604-1] [Cited by in Crossref: 48] [Cited by in F6Publishing: 12] [Article Influence: 2.3] [Reference Citation Analysis]
456 Zhou NE, Guo D, Thomas G, Reddy AV, Kaleta J, Purisima E, Menard R, Micetich RG, Singh R. 3-Acylamino-azetidin-2-one as a novel class of cysteine proteases inhibitors. Bioorganic & Medicinal Chemistry Letters 2003;13:139-41. [DOI: 10.1016/s0960-894x(02)00831-4] [Cited by in Crossref: 51] [Cited by in F6Publishing: 3] [Article Influence: 2.7] [Reference Citation Analysis]
457 Ramu E, Venkateswara Rao B. A short approach to the synthesis of the ritonavir and lopinavir core and its C-3 epimer via cross metathesis. Tetrahedron: Asymmetry 2009;20:2201-4. [DOI: 10.1016/j.tetasy.2009.09.003] [Cited by in Crossref: 11] [Cited by in F6Publishing: 4] [Article Influence: 0.8] [Reference Citation Analysis]
458 Kim Y, Uyama H, Kobayashi S. Inhibition effects of (+)-catechin–aldehyde polycondensates on proteinases causing proteolytic degradation of extracellular matrix. Biochemical and Biophysical Research Communications 2004;320:256-61. [DOI: 10.1016/j.bbrc.2004.05.163] [Cited by in Crossref: 51] [Cited by in F6Publishing: 44] [Article Influence: 2.8] [Reference Citation Analysis]
459 Hamada Y, Kiso Y. The application of bioisosteres in drug design for novel drug discovery: focusing on acid protease inhibitors. Expert Opin Drug Discov 2012;7:903-22. [PMID: 22873630 DOI: 10.1517/17460441.2012.712513] [Cited by in Crossref: 33] [Cited by in F6Publishing: 23] [Article Influence: 3.3] [Reference Citation Analysis]
460 D de Araujo A, Lim J, Wu KC, Xiang Y, Good AC, Skerlj R, Fairlie DP. Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins. J Med Chem 2018;61:2962-72. [PMID: 29584430 DOI: 10.1021/acs.jmedchem.8b00010] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 6.5] [Reference Citation Analysis]
461 Li X, Wang Y, Wu J, Li Y, Wang Q, Xu W. Novel aminopeptidase N inhibitors derived from antineoplaston AS2–5 (Part II). Bioorganic & Medicinal Chemistry 2009;17:3061-71. [DOI: 10.1016/j.bmc.2009.03.017] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 1.0] [Reference Citation Analysis]
462 Bhattacharya AK, Rana KC, Raut DS, Mhaindarkar VP, Khan MI. An efficient synthesis of benzodiazepinyl phosphonates as clostripain inhibitors via FeCl3 catalyzed four-component reaction. Org Biomol Chem 2011;9:5407. [DOI: 10.1039/c0ob01102a] [Cited by in Crossref: 24] [Cited by in F6Publishing: 20] [Article Influence: 2.2] [Reference Citation Analysis]
463 Kokotos G. Inhibition of digestive lipases by 2-oxo amide triacylglycerol analogues. Journal of Molecular Catalysis B: Enzymatic 2003;22:255-69. [DOI: 10.1016/s1381-1177(03)00041-9] [Cited by in Crossref: 4] [Article Influence: 0.2] [Reference Citation Analysis]
464 Hanessian S, Guesné S, Riber L, Marin J, Benoist A, Mennecier P, Rupin A, Verbeuren TJ, Nanteuil GD. Targeting ACE and ECE with dual acting inhibitors. Bioorganic & Medicinal Chemistry Letters 2008;18:1058-62. [DOI: 10.1016/j.bmcl.2007.12.013] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
465 Pietsch M, Gutschow M. Alternate substrate inhibition of cholesterol esterase by thieno[2,3-d][1,3]oxazin-4-ones. J Biol Chem 2002;277:24006-13. [PMID: 11959857 DOI: 10.1074/jbc.M112252200] [Cited by in Crossref: 46] [Cited by in F6Publishing: 3] [Article Influence: 2.3] [Reference Citation Analysis]
466 Milcent T, Hinks N, Bonnet-delpon D, Crousse B. Trifluoromethyl nitrones: from fluoral to optically active hydroxylamines. Org Biomol Chem 2010;8:3025. [DOI: 10.1039/c001791d] [Cited by in Crossref: 11] [Cited by in F6Publishing: 5] [Article Influence: 0.9] [Reference Citation Analysis]
467 Chen KX, Njoroge FG, Vibulbhan B, Buevich A, Chan T, Girijavallabhan V. Syntheses of Novel 4- tert -Alkyl Ether Proline-Based 16- and 17-Membered Macrocyclic Compounds. J Org Chem 2002;67:2730-3. [DOI: 10.1021/jo020075g] [Cited by in Crossref: 10] [Cited by in F6Publishing: 7] [Article Influence: 0.5] [Reference Citation Analysis]
468 Zhou NE, Kaleta J, Purisima E, Menard R, Micetich RG, Singh R. 6-Acylamino-penam derivatives: synthesis and inhibition of cathepsins B, L, K, and S. Bioorganic & Medicinal Chemistry Letters 2002;12:3417-9. [DOI: 10.1016/s0960-894x(02)00766-7] [Cited by in Crossref: 11] [Article Influence: 0.6] [Reference Citation Analysis]
469 Hanessian S, Seid M, Nilsson I. Stereocontrolled synthesis of enantiopure diversely functionalized prototypical piperidinone libraries, and constrained analogs of 4-substituted 2-amino adipic acid. Tetrahedron Letters 2002;43:1991-4. [DOI: 10.1016/s0040-4039(02)00183-1] [Cited by in Crossref: 18] [Article Influence: 0.9] [Reference Citation Analysis]
470 Agbowuro AA, Huston WM, Gamble AB, Tyndall JDA. Proteases and protease inhibitors in infectious diseases. Med Res Rev 2018;38:1295-331. [PMID: 29149530 DOI: 10.1002/med.21475] [Cited by in Crossref: 53] [Cited by in F6Publishing: 46] [Article Influence: 10.6] [Reference Citation Analysis]
471 Mittag T, Christensen KL, Lindsay KB, Nielsen NC, Skrydstrup T. Direct Entry to Peptidyl Ketones via SmI 2 -Mediated C−C Bond Formation with Readily Accessible N -Peptidyl Oxazolidinones. J Org Chem 2008;73:1088-92. [DOI: 10.1021/jo702286b] [Cited by in Crossref: 20] [Cited by in F6Publishing: 16] [Article Influence: 1.3] [Reference Citation Analysis]
472 Murumkar PR, DasGupta S, Chandani SR, Giridhar R, Yadav MR. Novel TACE inhibitors in drug discovery: a review of patented compounds. Expert Opin Ther Pat 2010;20:31-57. [PMID: 20021284 DOI: 10.1517/13543770903465157] [Cited by in Crossref: 41] [Cited by in F6Publishing: 39] [Article Influence: 3.4] [Reference Citation Analysis]
473 Wess G, Urmann M, Sickenberger B. Medicinal Chemistry: Challenges and Opportunities. Angew Chem Int Ed 2001;40:3341-50. [DOI: 10.1002/1521-3773(20010917)40:18<3341::aid-anie3341>3.0.co;2-d] [Cited by in Crossref: 83] [Article Influence: 4.0] [Reference Citation Analysis]
474 Mehta CH, Narayan R, Aithal G, Pandiyan S, Bhat P, Dengale S, Shah A, Nayak UY, Garg S. Molecular simulation driven experiment for formulation of fixed dose combination of Darunavir and Ritonavir as anti-HIV nanosuspension. Journal of Molecular Liquids 2019;293:111469. [DOI: 10.1016/j.molliq.2019.111469] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
475 Zhai Y, Zhao X, Cui Z, Wang M, Wang Y, Li L, Sun Q, Yang X, Zeng D, Liu Y, Sun Y, Lou Z, Shang L, Yin Z. Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease. J Med Chem 2015;58:9414-20. [PMID: 26571192 DOI: 10.1021/acs.jmedchem.5b01013] [Cited by in Crossref: 32] [Cited by in F6Publishing: 28] [Article Influence: 4.6] [Reference Citation Analysis]
476 Salah Ayoup M, Wahby Y, Abdel-hamid H, Ramadan ES, Teleb M, Abu-serie MM, Noby A. Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators. European Journal of Medicinal Chemistry 2019;168:340-56. [DOI: 10.1016/j.ejmech.2019.02.051] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 4.3] [Reference Citation Analysis]
477 Shirasaki Y, Miyashita H, Yamaguchi M, Inoue J, Nakamura M. Exploration of orally available calpain inhibitors: peptidyl alpha-ketoamides containing an amphiphile at P3 site. Bioorg Med Chem 2005;13:4473-84. [PMID: 15921914 DOI: 10.1016/j.bmc.2005.04.059] [Cited by in Crossref: 32] [Cited by in F6Publishing: 29] [Article Influence: 1.9] [Reference Citation Analysis]
478 Annedi SC, Majumder K, Wei L, Oyiliagu CE, Samson S, Kotra LP. Novel fluoropeptidomimetics: synthesis, stability studies and protease inhibition. Bioorganic & Medicinal Chemistry 2005;13:2943-58. [DOI: 10.1016/j.bmc.2005.02.011] [Cited by in Crossref: 8] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
479 Dahlgren A, Brånalt J, Kvarnström I, Nilsson I, Musil D, Samuelsson B. Synthesis of Potential Thrombin Inhibitors. Incorporation of Tartaric Acid Templates as P2 Proline Mimetics. Bioorganic & Medicinal Chemistry 2002;10:1567-80. [DOI: 10.1016/s0968-0896(01)00426-6] [Cited by in Crossref: 8] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
480 Volonterio A, Bravo P, Zanda M. Synthesis of Partially Modified Retro and Retroinverso ψ[NHCH(CF 3 )]-Peptides. Org Lett 2000;2:1827-30. [DOI: 10.1021/ol005876p] [Cited by in Crossref: 54] [Cited by in F6Publishing: 46] [Article Influence: 2.5] [Reference Citation Analysis]
481 Roy KK. Targeting the active sites of malarial proteases for antimalarial drug discovery: approaches, progress and challenges. Int J Antimicrob Agents 2017;50:287-302. [PMID: 28668681 DOI: 10.1016/j.ijantimicag.2017.04.006] [Cited by in Crossref: 22] [Cited by in F6Publishing: 18] [Article Influence: 4.4] [Reference Citation Analysis]
482 Bursavich MG, West CW, Rich DH. From Peptides to Non-Peptide Peptidomimetics:  Design and Synthesis of New Piperidine Inhibitors of Aspartic Peptidases. Org Lett 2001;3:2317-20. [DOI: 10.1021/ol016092u] [Cited by in Crossref: 49] [Cited by in F6Publishing: 36] [Article Influence: 2.3] [Reference Citation Analysis]
483 Kaboudin B, Sorbiun M. Solvent- and catalyst-free reaction of (aminomethyl)phosphonates with epoxides: Synthesis of novel {[(2-hydroxyethyl)amino]methyl}phosphonates. Heteroatom Chem 2010;21:284-9. [DOI: 10.1002/hc.20615] [Cited by in Crossref: 15] [Cited by in F6Publishing: 1] [Article Influence: 1.3] [Reference Citation Analysis]
484 Hanessian S, Auzzas L, Giannini G, Marzi M, Cabri W, Barbarino M, Vesci L, Pisano C. ω-Alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: A study of chain-length and stereochemical dependence. Bioorganic & Medicinal Chemistry Letters 2007;17:6261-5. [DOI: 10.1016/j.bmcl.2007.09.014] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 1.5] [Reference Citation Analysis]
485 Russo F, Wångsell F, Sävmarker J, Jacobsson M, Larhed M. Synthesis and evaluation of a new class of tertiary alcohol based BACE-1 inhibitors. Tetrahedron 2009;65:10047-59. [DOI: 10.1016/j.tet.2009.09.106] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 0.9] [Reference Citation Analysis]
486 Fernández M, Fernández L, Caballero J, Abreu JI, Reyes G. Proteochemometric Modeling of the Inhibition Complexes of Matrix Metalloproteinases with N -Hydroxy-2-[(Phenylsulfonyl)Amino]Acetamide Derivatives Using Topological Autocorrelation Interaction Matrix and Model Ensemble Averaging. Chemical Biology & Drug Design 2008;72:65-78. [DOI: 10.1111/j.1747-0285.2008.00675.x] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.4] [Reference Citation Analysis]
487 Krošlák E, Maliar T, Nemeček P, Viskupičová J, Maliarová M, Havrlentová M, Kraic J. Antioxidant and Proteinase Inhibitory Activities of Selected Poppy ( Papaver somniferum L.) Genotypes. Chem Biodiversity 2017;14:e1700176. [DOI: 10.1002/cbdv.201700176] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.2] [Reference Citation Analysis]
488 Liao D, Li Y, Chen J, Yu C. A fluorescence turn-on method for real-time monitoring of protease activity based on the electron transfer between a fluorophore labeled oligonucleotide and cytochrome c. Analytica Chimica Acta 2013;784:72-6. [DOI: 10.1016/j.aca.2013.04.066] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 2.6] [Reference Citation Analysis]
489 Baugh RJ, Dickinson CD, Ruf W, Krishnaswamy S. Exosite interactions determine the affinity of factor X for the extrinsic Xase complex. J Biol Chem 2000;275:28826-33. [PMID: 10889208 DOI: 10.1074/jbc.M005266200] [Cited by in Crossref: 66] [Cited by in F6Publishing: 23] [Article Influence: 3.0] [Reference Citation Analysis]
490 Thrithamarassery Gangadharan N, Venkatachalam AB, Sugathan S. High-Throughput and In Silico Screening in Drug Discovery. In: Abdulhameed S, Pradeep N, Sugathan S, editors. Bioresources and Bioprocess in Biotechnology. Singapore: Springer; 2017. pp. 247-73. [DOI: 10.1007/978-981-10-3573-9_11] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
491 Maliar T, Drobná J, Kraic J, Maliarová M, Jurovatá J. Proteinase inhibition and antioxidant activity of selected forage crops. Biologia 2011;66:96-103. [DOI: 10.2478/s11756-010-0149-9] [Cited by in Crossref: 8] [Cited by in F6Publishing: 3] [Article Influence: 0.7] [Reference Citation Analysis]
492 Hernick M, Fierke CA. Molecular recognition by Escherichia coli UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase is modulated by bound metal ions. Biochemistry 2006;45:14573-81. [PMID: 17144651 DOI: 10.1021/bi061625y] [Cited by in Crossref: 8] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
493 Yin H, Hamilton AD. Strategies for targeting protein-protein interactions with synthetic agents. Angew Chem Int Ed Engl 2005;44:4130-63. [PMID: 15954154 DOI: 10.1002/anie.200461786] [Cited by in Crossref: 378] [Cited by in F6Publishing: 338] [Article Influence: 23.6] [Reference Citation Analysis]
494 Tavares FX, Deaton DN, Miller AB, Miller LR, Wright LL, Zhou H. Potent and Selective Ketoamide-Based Inhibitors of Cysteine Protease, Cathepsin K. J Med Chem 2004;47:5049-56. [DOI: 10.1021/jm0400799] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
495 Macdonald SJ, Inglis GG, Bentley D, Dowle MD. Syntheses of templates derived from pyrrolidine trans -lactams as potential serine protease inhibitors. Tetrahedron Letters 2002;43:5057-60. [DOI: 10.1016/s0040-4039(02)01002-x] [Cited by in Crossref: 8] [Article Influence: 0.4] [Reference Citation Analysis]
496 Lee A, Ellman JA. Parallel Solution-Phase Synthesis of Mechanism-Based Cysteine Protease Inhibitors. Org Lett 2001;3:3707-9. [DOI: 10.1021/ol0166496] [Cited by in Crossref: 20] [Cited by in F6Publishing: 16] [Article Influence: 1.0] [Reference Citation Analysis]
497 Herroon MK, Sharma R, Rajagurubandara E, Turro C, Kodanko JJ, Podgorski I. Photoactivated inhibition of cathepsin K in a 3D tumor model. Biol Chem 2016;397:571-82. [PMID: 26901495 DOI: 10.1515/hsz-2015-0274] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 3.8] [Reference Citation Analysis]
498 Nedev HN, Klaiman G, Leblanc A, Saragovi HU. Synthesis and evaluation of novel dipeptidyl benzoyloxymethyl ketones as caspase inhibitors. Biochemical and Biophysical Research Communications 2005;336:397-400. [DOI: 10.1016/j.bbrc.2005.08.098] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
499 Fernández M, Caballero J, Tundidor-camba A. Linear and nonlinear QSAR study of N-hydroxy-2-[(phenylsulfonyl)amino]acetamide derivatives as matrix metalloproteinase inhibitors. Bioorganic & Medicinal Chemistry 2006;14:4137-50. [DOI: 10.1016/j.bmc.2006.01.072] [Cited by in Crossref: 39] [Cited by in F6Publishing: 36] [Article Influence: 2.4] [Reference Citation Analysis]
500 Zhao Y, Pirrung MC, Liao J. A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays. Mol BioSyst 2012;8:879. [DOI: 10.1039/c2mb05471j] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
501 Lindsay KB, Skrydstrup T. Formal Total Synthesis of the Potent Renin Inhibitor Aliskiren:  Application of a SmI 2 -Promoted Acyl-like Radical Coupling. J Org Chem 2006;71:4766-77. [DOI: 10.1021/jo060296c] [Cited by in Crossref: 43] [Cited by in F6Publishing: 29] [Article Influence: 2.7] [Reference Citation Analysis]
502 Mattiello L, da Silva FR, Menossi M. Linking microarray data to QTLs highlights new genes related to Al tolerance in maize. Plant Science 2012;191-192:8-15. [DOI: 10.1016/j.plantsci.2012.04.009] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 0.6] [Reference Citation Analysis]
503 Stasiulewicz A, Maksymiuk AW, Nguyen ML, Bełza B, Sulkowska JI. SARS-CoV-2 Papain-Like Protease Potential Inhibitors-In Silico Quantitative Assessment. Int J Mol Sci 2021;22:3957. [PMID: 33921228 DOI: 10.3390/ijms22083957] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
504 Asano T, Nakamura H, Uehara Y, Yamamoto Y. Design, synthesis, and biological evaluation of aminoboronic acids as growth-factor receptor inhibitors of EGFR and VEGFR-1 tyrosine kinases. Chembiochem. 2004;5:483-490. [PMID: 15185372 DOI: 10.1002/cbic.200300748] [Cited by in Crossref: 34] [Cited by in F6Publishing: 28] [Article Influence: 1.9] [Reference Citation Analysis]
505 Citron M. Human β-secretase and Alzheimer’s disease. Expert Opinion on Therapeutic Targets 2005;5:341-8. [DOI: 10.1517/14728222.5.3.341] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
506 Aweya JJ, Zheng Z, Zheng X, Yao D, Zhang Y. The expanding repertoire of immune‐related molecules with antimicrobial activity in penaeid shrimps: a review. Rev Aquacult 2021;13:1907-37. [DOI: 10.1111/raq.12551] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
507 Benedetti F, Maman P, Norbedo S. New synthesis of 5-amino-4-hydroxy-2,6-dimethylheptanoic acid, a hydroxyethylene isostere of the Val-Ala dipeptide. Tetrahedron Letters 2000;41:10075-8. [DOI: 10.1016/s0040-4039(00)01773-1] [Cited by in Crossref: 5] [Article Influence: 0.2] [Reference Citation Analysis]
508 Winssinger N, Ficarro S, Schultz PG, Harris JL. Profiling protein function with small molecule microarrays. Proc Natl Acad Sci U S A 2002;99:11139-44. [PMID: 12167675 DOI: 10.1073/pnas.172286899] [Cited by in Crossref: 130] [Cited by in F6Publishing: 115] [Article Influence: 6.5] [Reference Citation Analysis]
509 Chong FC, Tan WS, Biak DRA, Ling TC, Tey BT. Modulation of protease activity to enhance the recovery of recombinant nucleocapsid protein of Nipah virus. Process Biochemistry 2010;45:133-7. [DOI: 10.1016/j.procbio.2009.08.012] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
510 Murumkar PR, Giridhar R, Yadav MR. Novel methods and strategies in the discovery of TACE inhibitors. Expert Opin Drug Discov 2013;8:157-81. [PMID: 23231541 DOI: 10.1517/17460441.2013.744745] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
511 Deaton DN, Kumar S. Cathepsin K Inhibitors: Their Potential as Anti-Osteoporosis Agents. Elsevier; 2004. pp. 245-375. [DOI: 10.1016/s0079-6468(04)42006-2] [Cited by in Crossref: 22] [Article Influence: 1.2] [Reference Citation Analysis]
512 Doris E, Wagner A, Mioskowski C. α-Aminocyclopropanone hydrates: potential transition-state analog inhibitors of serine proteases. Tetrahedron Letters 2001;42:3183-5. [DOI: 10.1016/s0040-4039(01)00397-5] [Cited by in Crossref: 9] [Article Influence: 0.4] [Reference Citation Analysis]
513 Gonçalves R, Mateus N, de Freitas V. Biological Relevance of the Interaction between Procyanidins and Trypsin: A Multitechnique Approach. J Agric Food Chem 2010;58:11924-31. [DOI: 10.1021/jf1023356] [Cited by in Crossref: 34] [Cited by in F6Publishing: 33] [Article Influence: 2.8] [Reference Citation Analysis]
514 Khan N, Farina Y, Mun LK, Rajab NF, Awang N. Triorganotin(IV) complexes with o-substituted arylhydroxamates: Synthesis, spectroscopic characterization, X-ray structures and in vitro cytotoxic activities. Journal of Organometallic Chemistry 2014;763-764:26-33. [DOI: 10.1016/j.jorganchem.2014.04.015] [Cited by in Crossref: 12] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
515 Lima AR, Juliano L, Juliano MA. Cyclic, linear, cycloretro-isomer, and cycloretro-inverso peptides derived from the C-terminal sequence of bradykinin as substrates or inhibitors of serine and cysteine proteases. Protein J 2004;23:287-94. [PMID: 15214499 DOI: 10.1023/b:jopc.0000027853.93513.34] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
516 Huang Y, Xiao B, Xiong L. Characterization of a stress responsive proteinase inhibitor gene with positive effect in improving drought resistance in rice. Planta 2007;226:73-85. [DOI: 10.1007/s00425-006-0469-8] [Cited by in Crossref: 79] [Cited by in F6Publishing: 61] [Article Influence: 5.3] [Reference Citation Analysis]
517 Del Monte-Martínez A, González-Bacerio J, Cutiño-Avila B, Rojas J, Chappé M, Salas-Sarduy E, Pascual I, Guisán JM. Rational design and synthesis of affinity matrices based on proteases immobilized onto cellulose membranes. Prep Biochem Biotechnol 2017;47:745-53. [PMID: 28402172 DOI: 10.1080/10826068.2017.1315600] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
518 Mutahi Mw, Nittoli T, Guo L, Sieburth SM. Silicon-based metalloprotease inhibitors: synthesis and evaluation of silanol and silanediol peptide analogues as inhibitors of angiotensin-converting enzyme. J Am Chem Soc 2002;124:7363-75. [PMID: 12071745 DOI: 10.1021/ja026158w] [Cited by in Crossref: 129] [Cited by in F6Publishing: 99] [Article Influence: 6.5] [Reference Citation Analysis]
519 Hofbauer S, Brito JA, Mulchande J, Nogly P, Pessanha M, Moreira R, Archer M. Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking. Acta Crystallogr F Struct Biol Commun 2015;71:1346-51. [PMID: 26457529 DOI: 10.1107/S2053230X15017045] [Cited by in Crossref: 4] [Article Influence: 0.6] [Reference Citation Analysis]
520 Ruiz-Gómez G, Lim J, Halili MA, Le GT, Madala PK, Abbenante G, Fairlie DP. Structure-activity relationships for substrate-based inhibitors of human complement factor B. J Med Chem 2009;52:6042-52. [PMID: 19743866 DOI: 10.1021/jm900781m] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 0.7] [Reference Citation Analysis]
521 Zhao Q, Xue Y, Liu ZD, Li H, Wang JF, Li ZJ, Wang YM, Dong P, Xue CH. Differential effects of sulfated triterpene glycosides, holothurin A1, and 24-dehydroechinoside A, on antimetastasic activity via regulation of the MMP-9 signal pathway. J Food Sci 2010;75:H280-8. [PMID: 21535601 DOI: 10.1111/j.1750-3841.2010.01837.x] [Cited by in Crossref: 30] [Cited by in F6Publishing: 29] [Article Influence: 2.5] [Reference Citation Analysis]
522 Soto-Cairoli B, de Pomar JJ, Soderquist JA. Enantiomerically pure alpha-amino aldehydes from silylated alpha-amino acids. Org Lett 2008;10:333-6. [PMID: 18092797 DOI: 10.1021/ol7028993] [Cited by in Crossref: 29] [Cited by in F6Publishing: 16] [Article Influence: 1.9] [Reference Citation Analysis]
523 Rudolph M, Illig CR, Subasinghe NL, Wilson KJ, Hoffman JB, Randle T, Green D, Molloy CJ, Soll RM, Lewandowski F, Zhang M, Bone R, Spurlino JC, Deckman IC, Manthey C, Sharp C, Maguire D, Grasberger BL, Desjarlais RL, Zhou Z. Design and Synthesis of 4,5-Disubstituted-thiophene-2-amidines as Potent Urokinase Inhibitors. Bioorganic & Medicinal Chemistry Letters 2002;12:491-5. [DOI: 10.1016/s0960-894x(01)00787-9] [Cited by in Crossref: 22] [Cited by in F6Publishing: 2] [Article Influence: 1.1] [Reference Citation Analysis]
524 Garcia J, Mata EG, Tice CM, Hormann RE, Nicolas E, Albericio F, Michelotti EL. Evaluation of Solution and Solid-Phase Approaches to the Synthesis of Libraries of α,α-Disubstituted-α-acylaminoketones. J Comb Chem 2005;7:843-63. [DOI: 10.1021/cc0500396] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 0.5] [Reference Citation Analysis]
525 Schiffers I, Rantanen T, Schmidt F, Bergmans W, Zani L, Bolm C. Resolution of Racemic 2-Aminocyclohexanol Derivatives and Their Application as Ligands in Asymmetric Catalysis. J Org Chem 2006;71:2320-31. [DOI: 10.1021/jo052433w] [Cited by in Crossref: 76] [Cited by in F6Publishing: 54] [Article Influence: 4.8] [Reference Citation Analysis]
526 Rao NK, Yadav A, Kumar Singh S. An ab initio quantum mechanical drug designing procedure: application to the design of balanced dual ACE/NEP inhibitors. J Mol Model 2009;15:1447-62. [DOI: 10.1007/s00894-009-0500-7] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
527 Singh SB, Barrett JF. Empirical antibacterial drug discovery—Foundation in natural products. Biochemical Pharmacology 2006;71:1006-15. [DOI: 10.1016/j.bcp.2005.12.016] [Cited by in Crossref: 139] [Cited by in F6Publishing: 116] [Article Influence: 8.7] [Reference Citation Analysis]
528 Stoop AA, Craik CS. Engineering of a macromolecular scaffold to develop specific protease inhibitors. Nat Biotechnol 2003;21:1063-8. [DOI: 10.1038/nbt860] [Cited by in Crossref: 50] [Cited by in F6Publishing: 47] [Article Influence: 2.6] [Reference Citation Analysis]
529 Gobec S, Plantan I, Mravljak J, Wilson RA, Besra GS, Kikelj D. Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall. Bioorganic & Medicinal Chemistry Letters 2004;14:3559-62. [DOI: 10.1016/j.bmcl.2004.04.052] [Cited by in Crossref: 30] [Cited by in F6Publishing: 26] [Article Influence: 1.7] [Reference Citation Analysis]
530 Calugi C, Guarna A, Trabocchi A. Identification of constrained peptidomimetic chemotypes as HIV protease inhibitors. European Journal of Medicinal Chemistry 2014;84:444-53. [DOI: 10.1016/j.ejmech.2014.07.049] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 0.9] [Reference Citation Analysis]
531 Lin H, Han L, Yap C, Xue Y, Liu X, Zhu F, Chen Y. Prediction of factor Xa inhibitors by machine learning methods. Journal of Molecular Graphics and Modelling 2007;26:505-18. [DOI: 10.1016/j.jmgm.2007.03.003] [Cited by in Crossref: 18] [Cited by in F6Publishing: 16] [Article Influence: 1.2] [Reference Citation Analysis]
532 Wang Y, Huang J, Zhou Z, Yang W, Guastella J, Drewe J, Cai SX. Dipeptidyl aspartyl fluoromethylketones as potent caspase-3 inhibitors: SAR of the P 2 amino acid. Bioorganic & Medicinal Chemistry Letters 2004;14:1269-72. [DOI: 10.1016/j.bmcl.2003.12.065] [Cited by in Crossref: 12] [Cited by in F6Publishing: 11] [Article Influence: 0.7] [Reference Citation Analysis]
533 Smoum R, Rubinstein A, Srebnik M. Noncovalent inhibition of the serine proteases, alpha-chymotrypsin and trypsin by trifluoro(organo)borates. Org Biomol Chem 2005;3:941-4. [PMID: 15731882 DOI: 10.1039/b415957h] [Cited by in Crossref: 16] [Cited by in F6Publishing: 4] [Article Influence: 0.9] [Reference Citation Analysis]
534 Nielsen L, Lindsay KB, Faber J, Nielsen NC, Skrydstrup T. Stereocontrolled synthesis of methyl silanediol peptide mimics. J Org Chem 2007;72:10035-44. [PMID: 18001103 DOI: 10.1021/jo701907d] [Cited by in Crossref: 65] [Cited by in F6Publishing: 48] [Article Influence: 4.3] [Reference Citation Analysis]
535 Datta A, Veeresa G. A Stereoselective Route to Hydroxyethylamine Dipeptide Isosteres. J Org Chem 2000;65:7609-11. [DOI: 10.1021/jo001072b] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 0.9] [Reference Citation Analysis]
536 Debaene F, Mejias L, Harris JL, Winssinger N. Synthesis of a PNA-encoded cysteine protease inhibitor library. Tetrahedron 2004;60:8677-90. [DOI: 10.1016/j.tet.2004.05.107] [Cited by in Crossref: 36] [Cited by in F6Publishing: 26] [Article Influence: 2.0] [Reference Citation Analysis]
537 Moran BW, Anderson FP, Ruth DM, Fágáin CÓ, Dalton JP, Kenny PTM. Fluorobenzoyl dipeptidyl derivatives as inhibitors of the Fasciola hepatica cysteine protease cathepsin L1. Journal of Enzyme Inhibition and Medicinal Chemistry 2010;25:1-12. [DOI: 10.3109/14756360902888184] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
538 Li X, Yudin AK. Epimerization- and Protecting-Group-Free Synthesis of Peptidomimetic Conjugates from Amphoteric Amino Aldehydes. J Am Chem Soc 2007;129:14152-3. [DOI: 10.1021/ja076155p] [Cited by in Crossref: 30] [Cited by in F6Publishing: 28] [Article Influence: 2.0] [Reference Citation Analysis]
539 Rudzińska M, Daglioglu C, Savvateeva LV, Kaci FN, Antoine R, Zamyatnin AA Jr. Current Status and Perspectives of Protease Inhibitors and Their Combination with Nanosized Drug Delivery Systems for Targeted Cancer Therapy. Drug Des Devel Ther 2021;15:9-20. [PMID: 33442233 DOI: 10.2147/DDDT.S285852] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 3.0] [Reference Citation Analysis]
540 Jacoby E. Biphenyls as potential mimetics of protein α-helix. Bioorganic & Medicinal Chemistry Letters 2002;12:891-3. [DOI: 10.1016/s0960-894x(02)00031-8] [Cited by in Crossref: 45] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
541 Proniewicz E, Piergies N, Ozaki Y, Kim Y, Proniewicz LM. Investigation of adsorption mode of a novel group of N-benzylamino(boronphenyl)methylphosphonic acids using SERS. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2013;103:167-72. [DOI: 10.1016/j.saa.2012.10.040] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 1.0] [Reference Citation Analysis]
542 Sośnicki JG. Michael addition of nitroalkanes to nonactivated α,β-unsaturated δ-thiolactams: reactivity, diastereoselectivity, and comparison to α,β-unsaturated δ-lactams. Tetrahedron 2009;65:1336-48. [DOI: 10.1016/j.tet.2008.12.037] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 0.9] [Reference Citation Analysis]
543 Gosalia DN, Salisbury CM, Ellman JA, Diamond SL. High Throughput Substrate Specificity Profiling of Serine and Cysteine Proteases Using Solution-phase Fluorogenic Peptide Microarrays. Molecular & Cellular Proteomics 2005;4:626-36. [DOI: 10.1074/mcp.m500004-mcp200] [Cited by in Crossref: 129] [Cited by in F6Publishing: 34] [Article Influence: 7.6] [Reference Citation Analysis]
544 Hill TA, Shepherd NE, Diness F, Fairlie DP. Fixierung cyclischer Peptide: Mimetika von Proteinstrukturmotiven. Angew Chem 2014;126:13234-57. [DOI: 10.1002/ange.201401058] [Cited by in Crossref: 66] [Cited by in F6Publishing: 48] [Article Influence: 8.3] [Reference Citation Analysis]
545 Wu E, Han K, Zhang J. Selectivity of Neutral/Weakly Basic P1 Group Inhibitors of Thrombin and Trypsin by a Molecular Dynamics Study. Chem Eur J 2008;14:8704-14. [DOI: 10.1002/chem.200800277] [Cited by in Crossref: 59] [Cited by in F6Publishing: 51] [Article Influence: 4.2] [Reference Citation Analysis]
546 Peterlin-mašič L, Jurca A, Marinko P, Jančar A, Kikelj D. A general synthetic approach to novel conformationally restricted arginine side chain mimetics. Tetrahedron 2002;58:1557-63. [DOI: 10.1016/s0040-4020(01)01243-1] [Cited by in Crossref: 13] [Article Influence: 0.7] [Reference Citation Analysis]
547 Agarkov A, Chauhan S, Lory PJ, Gilbertson SR, Motin VL. Substrate specificity and screening of the integral membrane protease Pla. Bioorg Med Chem Lett 2008;18:427-31. [PMID: 17981463 DOI: 10.1016/j.bmcl.2007.09.104] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
548 Taboada L, Prieto L, Vidal P, Espinosa JF, Erickson JA. Solid-Phase Synthesis of Novel Trimers Containing a Phenylstatine Core and Analysis by High-Resolution Magic Angle Spinning. J Comb Chem 2007;9:748-55. [DOI: 10.1021/cc070001o] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
549 Zeng S, Xie H, Zeng L, Lu X, Zhao X, Zhang G, Tu Z, Xu H, Yang L, Zhang X, Hu W. Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization. Bioorganic & Medicinal Chemistry 2013;21:1749-55. [DOI: 10.1016/j.bmc.2013.01.062] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
550 Groutas WC, He S, Kuang R, Ruan S, Tu J, Chan H. Inhibition of serine proteases by functionalized sulfonamides coupled to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold. Bioorganic & Medicinal Chemistry 2001;9:1543-8. [DOI: 10.1016/s0968-0896(01)00037-2] [Cited by in Crossref: 30] [Cited by in F6Publishing: 5] [Article Influence: 1.4] [Reference Citation Analysis]
551 Fustero S, Chiva G, Piera J, Sanz-cervera JF, Volonterio A, Zanda M, Ramirez de Arellano C. New Fluorinated Peptidomimetics through Tandem Aza-Michael Addition to α-Trifluoromethyl Acrylamide Acceptors: Synthesis and Conformational Study in Solid State and Solution. J Org Chem 2009;74:3122-32. [DOI: 10.1021/jo9001867] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 1.2] [Reference Citation Analysis]
552 Phuong Vu L, Zyulina M, Hingst A, Schnakenburg G, Gütschow M. Combinatorial Assembly, Traceless Generation and In Situ Evaluation of Inhibitors for Therapeutically Relevant Serine Proteases. Bioorganic Chemistry 2022. [DOI: 10.1016/j.bioorg.2022.105676] [Reference Citation Analysis]
553 Citron M. Emerging Alzheimer’s disease therapies: inhibition of β-secretase. Neurobiology of Aging 2002;23:1017-22. [DOI: 10.1016/s0197-4580(02)00122-7] [Cited by in Crossref: 43] [Cited by in F6Publishing: 12] [Article Influence: 2.2] [Reference Citation Analysis]
554 Winum J, Scozzafava A, Montero J, Supuran CT. The sulfamide motif in the design of enzyme inhibitors. Expert Opinion on Therapeutic Patents 2005;16:27-47. [DOI: 10.1517/13543776.16.1.27] [Cited by in Crossref: 59] [Cited by in F6Publishing: 57] [Article Influence: 3.5] [Reference Citation Analysis]
555 Philippe C, Milcent T, Nguyen Thi Ngoc T, Crousse B, Bonnet-delpon D. Synthesis of New Trifluoromethylated Hydroxyethylamine-Based Scaffolds. Eur J Org Chem 2009;2009:5215-23. [DOI: 10.1002/ejoc.200900578] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]
556 Reid RC, Pattenden LK, Tyndall JDA, Martin JL, Walsh T, Fairlie DP. Countering Cooperative Effects in Protease Inhibitors Using Constrained β-Strand-Mimicking Templates in Focused Combinatorial Libraries. J Med Chem 2004;47:1641-51. [DOI: 10.1021/jm030337m] [Cited by in Crossref: 40] [Cited by in F6Publishing: 32] [Article Influence: 2.2] [Reference Citation Analysis]
557 Bravo P, Bruché L, Pesenti C, Viani F, Volonterio A, Zanda M. Solution and solid-phase synthesis of trifluoromethyl peptides and mimetics. Journal of Fluorine Chemistry 2001;112:153-62. [DOI: 10.1016/s0022-1139(01)00485-7] [Cited by in Crossref: 13] [Article Influence: 0.6] [Reference Citation Analysis]
558 Kim J, Glekas A, Sieburth SM. Silanediol-Based inhibitor of thermolysin. Bioorganic & Medicinal Chemistry Letters 2002;12:3625-7. [DOI: 10.1016/s0960-894x(02)00804-1] [Cited by in Crossref: 38] [Cited by in F6Publishing: 3] [Article Influence: 1.9] [Reference Citation Analysis]
559 Mou J, Fang H, Liu Y, Shang L, Wang Q, Zhang L, Xu W. Design, synthesis and primary activity assay of bi- or tri-peptide analogues with the scaffold l-arginine as amino-peptidase N/CD13 inhibitors. Bioorg Med Chem 2010;18:887-95. [PMID: 19969464 DOI: 10.1016/j.bmc.2009.11.036] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
560 Garsi JB, Aguiar PM, Hanessian S. Design of Pseudodiproline Dimers as Mimetics of Pro-Pro Units: Stereocontrolled Synthesis, Configurational Relevance, and Structural Properties. J Org Chem 2021;86:16834-47. [PMID: 34749500 DOI: 10.1021/acs.joc.1c02061] [Reference Citation Analysis]
561 Karvinen J, Elomaa A, Mäkinen M, Hakala H, Mukkala V, Peuralahti J, Hurskainen P, Hovinen J, Hemmilä I. Caspase multiplexing: simultaneous homogeneous time-resolved quenching assay (TruPoint) for caspases 1, 3, and 6. Analytical Biochemistry 2004;325:317-25. [DOI: 10.1016/j.ab.2003.10.044] [Cited by in Crossref: 31] [Cited by in F6Publishing: 28] [Article Influence: 1.7] [Reference Citation Analysis]
562 Hu J, Liu F, Ju H. Peptide Code-on-a-Microplate for Protease Activity Analysis via MALDI-TOF Mass Spectrometric Quantitation. Anal Chem 2015;87:4409-14. [DOI: 10.1021/acs.analchem.5b00230] [Cited by in Crossref: 25] [Cited by in F6Publishing: 20] [Article Influence: 3.6] [Reference Citation Analysis]
563 Kim J, Hewitt G, Carroll P, Sieburth SM. Silanediol inhibitors of angiotensin-converting enzyme. Synthesis and evaluation of four diastereomers of Phe[Si]Ala dipeptide analogues. J Org Chem 2005;70:5781-9. [PMID: 16018669 DOI: 10.1021/jo048121v] [Cited by in Crossref: 49] [Cited by in F6Publishing: 39] [Article Influence: 2.9] [Reference Citation Analysis]
564 Chen D, Cai J, Cheng J, Jing C, Yin J, Jiang J, Peng Z, Hao X. Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition. Sci Rep 2015;5:14972. [PMID: 26443922 DOI: 10.1038/srep14972] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 2.6] [Reference Citation Analysis]
565 Sharma A, Khuller GK, Sharma S. Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery. Expert Opin Ther Targets 2009;13:753-65. [PMID: 19530983 DOI: 10.1517/14728220903005590] [Cited by in Crossref: 22] [Cited by in F6Publishing: 18] [Article Influence: 1.7] [Reference Citation Analysis]
566 Wang D, Brömme D. Drug delivery strategies for cathepsin inhibitors in joint diseases. Expert Opin Drug Deliv 2005;2:1015-28. [PMID: 16296806 DOI: 10.1517/17425247.2.6.1015] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 1.1] [Reference Citation Analysis]
567 Bhattacharjee C, Manjunath NH, Prasad DT. Purification of a trypsin inhibitor from Cocculus hirsutus and identification of its biological activity. J Crop Sci Biotechnol 2009;12:253-60. [DOI: 10.1007/s12892-009-0094-8] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
568 Fairlie DP. Small Molecules that Mimic Components of Bioactive Protein Surfaces. Aust J Chem 2004;57:855. [DOI: 10.1071/ch04074] [Cited by in Crossref: 3] [Article Influence: 0.2] [Reference Citation Analysis]
569 Oubella A, Taia A, Byadi S, Ait Lahcen M, Bimoussa A, Essaber M, Podlipnik C, Morjani H, Ait Itto MY, Aatif A. Chemical profiling, cytotoxic activities through apoptosis induction in human fibrosarcoma and carcinoma cells, and molecular docking of some 1,2,3-triazole-isoxazoline hybrids using the eugenol as a precursors. J Biomol Struct Dyn 2022;:1-13. [PMID: 35174765 DOI: 10.1080/07391102.2022.2037466] [Reference Citation Analysis]
570 Ma Y, Yao A, Chen X, Wang L, Ma C, Xi X, Chen T, Shaw C, Zhou M. Generation of truncated derivatives through in silico enzymatic digest of peptide GV30 target MRSA both in vitro and in vivo. Comput Struct Biotechnol J 2021;19:4984-96. [PMID: 34584638 DOI: 10.1016/j.csbj.2021.08.039] [Reference Citation Analysis]
571 Riber D, Skrydstrup T. SmI 2 -Promoted Radical Addition of Nitrones to α,β-Unsaturated Amides and Esters:  Synthesis of γ-Amino Acids via a Nitrogen Equivalent to the Ketyl Radical. Org Lett 2003;5:229-31. [DOI: 10.1021/ol027386y] [Cited by in Crossref: 87] [Cited by in F6Publishing: 67] [Article Influence: 4.4] [Reference Citation Analysis]
572 Bianchini G, Aschi M, Cavicchio G, Crucianelli M, Preziuso S, Gallina C, Nastari A, Gavuzzo E, Mazza F. Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8. Bioorganic & Medicinal Chemistry 2005;13:4740-9. [DOI: 10.1016/j.bmc.2005.04.079] [Cited by in Crossref: 26] [Cited by in F6Publishing: 19] [Article Influence: 1.5] [Reference Citation Analysis]
573 Seo J, Silverman RB. Synthesis of arginine-containing hydroxamate dipeptidomimetics. Tetrahedron Letters 2006;47:4069-73. [DOI: 10.1016/j.tetlet.2006.03.190] [Cited by in Crossref: 7] [Cited by in F6Publishing: 3] [Article Influence: 0.4] [Reference Citation Analysis]
574 Pochet L, Dieu M, Frédérick R, Murray A, Kempen I, Pirotte B, Masereel B. Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry. Tetrahedron 2003;59:4557-61. [DOI: 10.1016/s0040-4020(03)00660-4] [Cited by in Crossref: 7] [Article Influence: 0.4] [Reference Citation Analysis]
575 Leung D, Hardouin C, Boger DL, Cravatt BF. Discovering potent and selective reversible inhibitors of enzymes in complex proteomes. Nat Biotechnol 2003;21:687-91. [DOI: 10.1038/nbt826] [Cited by in Crossref: 270] [Cited by in F6Publishing: 252] [Article Influence: 14.2] [Reference Citation Analysis]
576 Kim J, Sieburth SM. A silanediol inhibitor of the metalloprotease thermolysin: synthesis and comparison with a phosphinic acid inhibitor. J Org Chem 2004;69:3008-14. [PMID: 15104438 DOI: 10.1021/jo049929i] [Cited by in Crossref: 35] [Cited by in F6Publishing: 27] [Article Influence: 1.9] [Reference Citation Analysis]
577 Pehere AD, Pietsch M, Gütschow M, Neilsen PM, Pedersen DS, Nguyen S, Zvarec O, Sykes MJ, Callen DF, Abell AD. Synthesis and extended activity of triazole-containing macrocyclic protease inhibitors. Chemistry 2013;19:7975-81. [PMID: 23606616 DOI: 10.1002/chem.201204260] [Cited by in Crossref: 23] [Cited by in F6Publishing: 17] [Article Influence: 2.6] [Reference Citation Analysis]
578 Gautier A, Pitrat D, Hasserodt J. An unusual functional group interaction and its potential to reproduce steric and electrostatic features of the transition states of peptidolysis. Bioorganic & Medicinal Chemistry 2006;14:3835-47. [DOI: 10.1016/j.bmc.2006.01.031] [Cited by in Crossref: 25] [Cited by in F6Publishing: 20] [Article Influence: 1.6] [Reference Citation Analysis]
579 Oubella A, Fawzi M, Bimoussa A, N’ait Ousidi A, Auhmani A, Riahi A, Robert A, El Firdoussi L, Morjani H, Ait Itto MY. Convenient route to benzo[1,2,3]selenadiazole–isoxazole hybrids and evaluation of their in vitro cytotoxicity. Chem Pap . [DOI: 10.1007/s11696-022-02083-6] [Reference Citation Analysis]
580 Haddoub R, Dauner M, Stefanowicz FA, Barattini V, Laurent N, Flitsch SL. Enzymatic synthesis of peptides on a solid support. Org Biomol Chem 2009;7:665-70. [PMID: 19194581 DOI: 10.1039/b816847d] [Cited by in Crossref: 10] [Cited by in F6Publishing: 1] [Article Influence: 0.7] [Reference Citation Analysis]
581 Nie X, Wang G. Synthesis of a ring-oxygenated variant of the 2-carboxy-6-hydroxyoctahydroindole core of aeruginosin 298-A from glucose. J Org Chem 2005;70:8687-92. [PMID: 16238296 DOI: 10.1021/jo0507901] [Cited by in Crossref: 27] [Cited by in F6Publishing: 23] [Article Influence: 1.7] [Reference Citation Analysis]
582 Svenson J, Vergote V, Karstad R, Burvenich C, Svendsen JS, De Spiegeleer B. Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the In Vitro Metabolic Stability. J Pharmacol Exp Ther 2010;332:1032-9. [DOI: 10.1124/jpet.109.162826] [Cited by in Crossref: 29] [Cited by in F6Publishing: 28] [Article Influence: 2.2] [Reference Citation Analysis]
583 Clare BW, Scozzafava A, Supuran CT. Protease Inhibitors, Part 13: Specific, Weakly Basic Thrombin Inhibitors Incorporating Sulfonyl Dicyandiamide Moieties in their Structure. Journal of Enzyme Inhibition 2010;16:1-13. [DOI: 10.1080/14756360109162351] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.3] [Reference Citation Analysis]
584 Koparir P, Karaarslan M, Orek C, Koparir M. Synthesis and In-Vitro Antimicrobial Activity of Novel Aminophosphinic Acids Containing Cyclobutane and 1,3-Thiazole. Phosphorus, Sulfur, and Silicon and the Related Elements 2011;186:2368-76. [DOI: 10.1080/10426507.2011.604660] [Cited by in Crossref: 17] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
585 Ochoa R, Magnitov M, Laskowski RA, Cossio P, Thornton JM. An automated protocol for modelling peptide substrates to proteases. BMC Bioinformatics 2020;21:586. [PMID: 33375946 DOI: 10.1186/s12859-020-03931-6] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
586 Hesek D, Noll BC, Mobashery S. Side Reaction of Significance in Preparation of Peptide- or Peptidomimetic-Based Hydroxamate Enzyme Inhibitors. J Org Chem 2006;71:2885-7. [DOI: 10.1021/jo052546f] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
587 Gonçalves R, Mateus N, De Freitas V. Influence of Carbohydrates on the Interaction of Procyanidin B3 with Trypsin. J Agric Food Chem 2011;59:11794-802. [DOI: 10.1021/jf203060s] [Cited by in Crossref: 34] [Cited by in F6Publishing: 26] [Article Influence: 3.1] [Reference Citation Analysis]
588 Kumaran S, Gupta SP. A quantitative structure-activity relationship study on matrix metalloproteinase inhibitors: Piperidine sulfonamide aryl hydroxamic acid analogs. Journal of Enzyme Inhibition and Medicinal Chemistry 2007;22:23-7. [DOI: 10.1080/14756360600956655] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
589 Bueno AB, Agejas J, Broughton H, Dally R, Durham TB, Espinosa JF, González R, Hahn PJ, Marcos A, Rodríguez R, Sanz G, Soriano JF, Timm D, Vidal P, Yang HC, McCarthy JR. Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J Med Chem 2017;60:9807-20. [PMID: 29088532 DOI: 10.1021/acs.jmedchem.7b01304] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
590 Garrec J, Cascella M, Rothlisberger U, Fleurat-lessard P. Low Inhibiting Power of N···CO Based Peptidomimetic Compounds against HIV-1 Protease: Insights from a QM/MM Study. J Chem Theory Comput 2010;6:1369-79. [DOI: 10.1021/ct9004728] [Cited by in Crossref: 7] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
591 Subramanyam C, Chang SP. Solid-phase synthesis of peptidyl α-keto heterocycles. Tetrahedron Letters 2002;43:6313-5. [DOI: 10.1016/s0040-4039(02)01402-8] [Cited by in Crossref: 7] [Article Influence: 0.4] [Reference Citation Analysis]
592 Kant BR, Kant BS, Chand BT, Kumar BA. Green Synthesis of Hydroxamic Acid and Its Potential Industrial Applications. In: Kalia VC, editor. Microbial Applications Vol.2. Cham: Springer International Publishing; 2017. pp. 169-84. [DOI: 10.1007/978-3-319-52669-0_9] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
593 Chun J, Yin YI, Yang G, Tarassishin L, Li YM. Stereoselective synthesis of photoreactive peptidomimetic gamma-secretase inhibitors. J Org Chem 2004;69:7344-7. [PMID: 15471490 DOI: 10.1021/jo0486948] [Cited by in Crossref: 36] [Cited by in F6Publishing: 31] [Article Influence: 2.0] [Reference Citation Analysis]
594 Leiris S, Davies DT, Sprynski N, Castandet J, Beyria L, Bodnarchuk MS, Sutton JM, Mullins TMG, Jones MW, Forrest AK, Pallin TD, Karunakar P, Martha SK, Parusharamulu B, Ramula R, Kotha V, Pottabathini N, Pothukanuri S, Lemonnier M, Everett M. Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors. ACS Med Chem Lett 2021;12:217-27. [PMID: 33603968 DOI: 10.1021/acsmedchemlett.0c00554] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
595 Fernández-Bachiller MI, Horatscheck A, Lisurek M, Rademann J. Alzheimer's disease: identification and development of β-secretase (BACE-1) binding fragments and inhibitors by dynamic ligation screening (DLS). ChemMedChem 2013;8:1041-56. [PMID: 23757181 DOI: 10.1002/cmdc.201300078] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.3] [Reference Citation Analysis]
596 González-Naranjo P, Pérez-Macias N, Pérez C, Roca C, Vaca G, Girón R, Sánchez-Robles E, Martín-Fontelles MI, de Ceballos ML, Martin-Requero A, Campillo NE, Páez JA. Indazolylketones as new multitarget cannabinoid drugs. Eur J Med Chem 2019;166:90-107. [PMID: 30685536 DOI: 10.1016/j.ejmech.2019.01.030] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 3.0] [Reference Citation Analysis]
597 Hedstrom L. An overview of serine proteases. Curr Protoc Protein Sci 2002;Chapter 21:Unit 21.10. [PMID: 18429229 DOI: 10.1002/0471140864.ps2110s26] [Cited by in Crossref: 6] [Cited by in F6Publishing: 20] [Article Influence: 0.4] [Reference Citation Analysis]
598 Ratia K, Pegan S, Takayama J, Sleeman K, Coughlin M, Baliji S, Chaudhuri R, Fu W, Prabhakar BS, Johnson ME, Baker SC, Ghosh AK, Mesecar AD. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A 2008;105:16119-24. [PMID: 18852458 DOI: 10.1073/pnas.0805240105] [Cited by in Crossref: 234] [Cited by in F6Publishing: 219] [Article Influence: 16.7] [Reference Citation Analysis]
599 Clare BW, Scozzafava A, Supuran CT. Protease inhibitors: synthesis of a series of bacterial collagenase inhibitors of the sulfonyl amino acyl hydroxamate type. J Med Chem 2001;44:2253-8. [PMID: 11405662 DOI: 10.1021/jm010087e] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 1.2] [Reference Citation Analysis]
600 Piergies N, Proniewicz E, Kim Y, Proniewicz LM. Interaction of N -benzylamino(boronphenyl)methylphosphonic acid analogs with the gold colloidal surface under different concentration and pH conditions: Interaction of N -benzylamino(boronphenyl)methylphosphonic acid analogs. J Raman Spectrosc 2014;45:581-90. [DOI: 10.1002/jrs.4505] [Cited by in Crossref: 8] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
601 Lazareva NF. N-(silylmethyl)amines, -amides, and -amino acids: biological activity and prospects in drug synthesis. Russ Chem Bull 2011;60:615-32. [DOI: 10.1007/s11172-011-0097-8] [Cited by in Crossref: 9] [Article Influence: 0.8] [Reference Citation Analysis]
602 Wang W, Maniar M, Jain R, Jacobs J, Trias J, Yuan Z. A fluorescence-based homogeneous assay for measuring activity of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase. Anal Biochem 2001;290:338-46. [PMID: 11237337 DOI: 10.1006/abio.2000.4973] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 0.5] [Reference Citation Analysis]
603 Choi S, Cho J, Im I, Lee S, Jang J, Oh Y, Jung Y, Jeon E, Kim Y. Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors. European Journal of Medicinal Chemistry 2010;45:2578-90. [DOI: 10.1016/j.ejmech.2010.02.046] [Cited by in Crossref: 23] [Cited by in F6Publishing: 15] [Article Influence: 1.9] [Reference Citation Analysis]
604 Pešić M, Božić N, López C, Lončar N, Álvaro G, Vujčić Z. Chemical modification of chloroperoxidase for enhanced stability and activity. Process Biochemistry 2014;49:1472-9. [DOI: 10.1016/j.procbio.2014.05.025] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
605 Nakamura M, Miyashita H, Yamaguchi M, Shirasaki Y, Nakamura Y, Inoue J. Novel 6-Hydroxy-3-morpholinones as cornea permeable calpain inhibitors. Bioorganic & Medicinal Chemistry 2003;11:5449-60. [DOI: 10.1016/j.bmc.2003.09.031] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 0.8] [Reference Citation Analysis]
606 Ghosh AK, Brindisi M. Organic carbamates in drug design and medicinal chemistry. J Med Chem 2015;58:2895-940. [PMID: 25565044 DOI: 10.1021/jm501371s] [Cited by in Crossref: 277] [Cited by in F6Publishing: 218] [Article Influence: 39.6] [Reference Citation Analysis]
607 Sova M, Kovac A, Turk S, Hrast M, Blanot D, Gobec S. Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF. Bioorg Chem 2009;37:217-22. [PMID: 19804894 DOI: 10.1016/j.bioorg.2009.09.001] [Cited by in Crossref: 31] [Cited by in F6Publishing: 21] [Article Influence: 2.4] [Reference Citation Analysis]
608 Montero A, Alonso M, Benito E, Chana A, Mann E, Navas JM, Herradón B. Studies on aromatic compounds: inhibition of calpain I by biphenyl derivatives and peptide-biphenyl hybrids. Bioorg Med Chem Lett 2004;14:2753-7. [PMID: 15125927 DOI: 10.1016/j.bmcl.2004.03.071] [Cited by in Crossref: 19] [Cited by in F6Publishing: 16] [Article Influence: 1.1] [Reference Citation Analysis]
609 Ekins S, Mestres J, Testa B. In silico pharmacology for drug discovery: applications to targets and beyond. Br J Pharmacol 2007;152:21-37. [PMID: 17549046 DOI: 10.1038/sj.bjp.0707306] [Cited by in Crossref: 181] [Cited by in F6Publishing: 149] [Article Influence: 12.1] [Reference Citation Analysis]
610 Breusegem SY, Sadat-Ebrahimi SE, Douglas KT, Bichenkova EV, Clegg RM, Loontiens FG. Experimental precedent for the need to involve the primary hydration layer of DNA in lead drug design. J Med Chem 2001;44:2503-6. [PMID: 11472203 DOI: 10.1021/jm0100943] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 0.6] [Reference Citation Analysis]
611 šille J, Remko M. Computational Study of the Sulfonylated Amino Acid Hydroxamates Binding to the Zinc Ion within the Active Site of Carbonic Anhydrase. Journal of Biomolecular Structure and Dynamics 2009;26:431-44. [DOI: 10.1080/07391102.2009.10507258] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 0.9] [Reference Citation Analysis]
612 Abel R, Salam NK, Shelley J, Farid R, Friesner RA, Sherman W. Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases. ChemMedChem 2011;6:1049-66. [PMID: 21506273 DOI: 10.1002/cmdc.201000533] [Cited by in Crossref: 102] [Cited by in F6Publishing: 92] [Article Influence: 9.3] [Reference Citation Analysis]
613 Sridharan V, Maiti S, Menéndez JC. Efficient Generation of Highly Functionalized Fused Oxazepine Frameworks Based on a CAN-Catalyzed Four-Component Tetrahydropyridine Synthesis/Ring-Closing Metathesis Sequence. J Org Chem 2009;74:9365-71. [DOI: 10.1021/jo9021309] [Cited by in Crossref: 36] [Cited by in F6Publishing: 27] [Article Influence: 2.8] [Reference Citation Analysis]
614 Haq SK, Rabbani G, Ahmad E, Atif SM, Khan RH. Protease inhibitors: a panacea? J Biochem Mol Toxicol 2010;24:270-7. [PMID: 20135636 DOI: 10.1002/jbt.20335] [Cited by in Crossref: 22] [Cited by in F6Publishing: 18] [Article Influence: 1.8] [Reference Citation Analysis]
615 Liu B, Lu C. Asymmetric Synthesis of cis -2-Aminocyclopropanols by Intramolecular Mannich Addition of Silyloxy Benzyl Carbanions. J Org Chem 2011;76:4205-9. [DOI: 10.1021/jo200585r] [Cited by in Crossref: 20] [Cited by in F6Publishing: 10] [Article Influence: 1.8] [Reference Citation Analysis]
616 Castro E, Cerón MR, Garcia AH, Kim Q, Etcheverry-Berríos A, Morel M, Díaz-Torres R, Qian W, Martinez Z, Mendez L, Perez F, Santoyo CA, Gimeno-Muñoz R, Esper R, Gutierrez DA, Varela-Ramirez A, Aguilera RJ, Llano M, Soler M, Aliaga-Alcalde N, Echegoyen L. A new family of fullerene derivatives: Fullerene-curcumin conjugates for biological and photovoltaic applications. RSC Adv 2018;8:41692-8. [PMID: 31543960 DOI: 10.1039/C8RA08334G] [Cited by in Crossref: 9] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
617 Matarrese P, Nencioni L, Checconi P, Ciarlo L, Gambardella L, Ascione B, Sgarbanti R, Garaci E, Malorni W, Palamara AT. Pepstatin A alters host cell autophagic machinery and leads to a decrease in influenza A virus production. J Cell Physiol 2011;226:3368-77. [DOI: 10.1002/jcp.22696] [Cited by in Crossref: 24] [Cited by in F6Publishing: 24] [Article Influence: 2.2] [Reference Citation Analysis]
618 Mcbride JD, Freeman HN, Leatherbarrow RJ. Identification of chymotrypsin inhibitors from a second-generation template assisted combinatorial peptide library. J Peptide Sci 2000;6:446-52. [DOI: 10.1002/1099-1387(200009)6:9<446::aid-psc283>3.0.co;2-u] [Cited by in Crossref: 14] [Article Influence: 0.6] [Reference Citation Analysis]
619 Zhang H, Kasibhatla S, Guastella J, Tseng B, Drewe J, Cai SX. N -Ac-DEVD- N ‘-(Polyfluorobenzoyl)−R110:  Novel Cell-Permeable Fluorogenic Caspase Substrates for the Detection of Caspase Activity and Apoptosis. Bioconjugate Chem 2003;14:458-63. [DOI: 10.1021/bc0256188] [Cited by in Crossref: 47] [Cited by in F6Publishing: 48] [Article Influence: 2.5] [Reference Citation Analysis]
620 Temperini C, Innocenti A, Guerri A, Scozzafava A, Rusconi S, Supuran CT. Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I. Bioorganic & Medicinal Chemistry Letters 2007;17:2210-5. [DOI: 10.1016/j.bmcl.2007.01.113] [Cited by in Crossref: 42] [Cited by in F6Publishing: 37] [Article Influence: 2.8] [Reference Citation Analysis]
621 Gütschow M, Powers JC. 2-Alkylthio-4-oxo-3-quinazolineacetonitriles and Analogous Thieno[3,2- d ]pyrimidineacetonitriles:  Reaction with Thiols via Trapped Thioimidates. J Org Chem 2001;66:4723-7. [DOI: 10.1021/jo010045y] [Cited by in Crossref: 13] [Cited by in F6Publishing: 8] [Article Influence: 0.6] [Reference Citation Analysis]