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For: Meanwell NA. 2015 Philip S. Portoghese Medicinal Chemistry Lectureship. Curing Hepatitis C Virus Infection with Direct-Acting Antiviral Agents: The Arc of a Medicinal Chemistry Triumph. J Med Chem 2016;59:7311-51. [PMID: 27501244 DOI: 10.1021/acs.jmedchem.6b00915] [Cited by in Crossref: 28] [Cited by in F6Publishing: 20] [Article Influence: 4.7] [Reference Citation Analysis]
Number Citing Articles
1 Wang B, Zhang C, Tian X, Lin J, Yan S. Cascade Reaction of Isatins with 1,1-Enediamines: Synthesis of Multisubstituted Quinoline-4-carboxamides. Org Lett 2018;20:660-3. [DOI: 10.1021/acs.orglett.7b03803] [Cited by in Crossref: 46] [Cited by in F6Publishing: 25] [Article Influence: 11.5] [Reference Citation Analysis]
2 Li J, Eastgate MD. Making better decisions during synthetic route design: leveraging prediction to achieve greenness-by-design. React Chem Eng 2019;4:1595-607. [DOI: 10.1039/c9re00019d] [Cited by in Crossref: 17] [Article Influence: 5.7] [Reference Citation Analysis]
3 De Rycker M, Baragaña B, Duce SL, Gilbert IH. Challenges and recent progress in drug discovery for tropical diseases. Nature 2018;559:498-506. [PMID: 30046073 DOI: 10.1038/s41586-018-0327-4] [Cited by in Crossref: 73] [Cited by in F6Publishing: 63] [Article Influence: 18.3] [Reference Citation Analysis]
4 Matthew AN, Zephyr J, Hill CJ, Jahangir M, Newton A, Petropoulos CJ, Huang W, Kurt-Yilmaz N, Schiffer CA, Ali A. Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants. J Med Chem 2017;60:5699-716. [PMID: 28594175 DOI: 10.1021/acs.jmedchem.7b00426] [Cited by in Crossref: 24] [Cited by in F6Publishing: 22] [Article Influence: 4.8] [Reference Citation Analysis]
5 Alizadeh A, Roosta A, Halvagar M. Four-Component Regio- and Diastereoselective Synthesis of Pyrrolizidines Incorporating Spiro-Oxindole/Indanedione via 1,3-Dipolar Cycloaddition Reaction of Azomethine Ylides. ChemistrySelect 2019;4:71-4. [DOI: 10.1002/slct.201803418] [Cited by in Crossref: 9] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
6 Meanwell NA, Georg GI, Wang S. The 2020 Nobel Prize in Physiology or Medicine. J Med Chem 2020;63:13197-204. [PMID: 33147952 DOI: 10.1021/acs.jmedchem.0c01877] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
7 Yeung KS, Beno BR, Mosure K, Zhu J, Grant-Young KA, Parcella K, Anjanappa P, Bora RO, Selvakumar K, Wang YK, Fang H, Krause R, Rigat K, Liu M, Lemm J, Sheriff S, Witmer M, Tredup J, Jardel A, Kish K, Parker D, Haskell R, Santone K, Meanwell NA, Soars MG, Roberts SB, Kadow JF. Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors. ACS Med Chem Lett 2018;9:1217-22. [PMID: 30613329 DOI: 10.1021/acsmedchemlett.8b00379] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
8 Kim BW, Lee H, Keum G, Kim BM. Structure-activity relationship (SAR) studies on the mutagenic properties of 2,7-diaminofluorene and 2,7-diaminocarbazole derivatives. Bioorg Med Chem Lett 2021;31:127662. [PMID: 33227415 DOI: 10.1016/j.bmcl.2020.127662] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
9 Yeung KS, Beno BR, Parcella K, Bender JA, Grant-Young KA, Nickel A, Gunaga P, Anjanappa P, Bora RO, Selvakumar K, Rigat K, Wang YK, Liu M, Lemm J, Mosure K, Sheriff S, Wan C, Witmer M, Kish K, Hanumegowda U, Zhuo X, Shu YZ, Parker D, Haskell R, Ng A, Gao Q, Colston E, Raybon J, Grasela DM, Santone K, Gao M, Meanwell NA, Sinz M, Soars MG, Knipe JO, Roberts SB, Kadow JF. Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. J Med Chem 2017;60:4369-85. [PMID: 28430437 DOI: 10.1021/acs.jmedchem.7b00328] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 3.0] [Reference Citation Analysis]
10 Calcaterra A, D’acquarica I. The market of chiral drugs: Chiral switches versus de novo enantiomerically pure compounds. Journal of Pharmaceutical and Biomedical Analysis 2018;147:323-40. [DOI: 10.1016/j.jpba.2017.07.008] [Cited by in Crossref: 148] [Cited by in F6Publishing: 103] [Article Influence: 37.0] [Reference Citation Analysis]
11 Wypych RM, LaPlante SR, White PW, Martin SF. Structure-thermodynamics-relationships of hepatitis C viral NS3 protease inhibitors. Eur J Med Chem 2020;192:112195. [PMID: 32151833 DOI: 10.1016/j.ejmech.2020.112195] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
12 Wu Y, Jiang S, Ying T. Single-Domain Antibodies As Therapeutics against Human Viral Diseases. Front Immunol 2017;8:1802. [PMID: 29326699 DOI: 10.3389/fimmu.2017.01802] [Cited by in Crossref: 43] [Cited by in F6Publishing: 39] [Article Influence: 8.6] [Reference Citation Analysis]
13 R. C, Pise A, Shah SK, D. R, Baluni A, Tiwari KN. Aqueous NH 3 -mediated syntheses of 2-styrylquinoline-4-carboxamides by domino ring opening cyclization strategy. Synthetic Communications 2021;51:245-55. [DOI: 10.1080/00397911.2020.1822409] [Reference Citation Analysis]
14 Singh J. The Ascension of Targeted Covalent Inhibitors. J Med Chem 2022. [PMID: 35439421 DOI: 10.1021/acs.jmedchem.1c02134] [Reference Citation Analysis]
15 Ramaraju A, Chouhan NK, Ravi O, Sridhar B, Bathula SR. Cu-Catalyzed Coupling of O -Acyl Oximes with Isatins: Domino Rearrangement Strategy for Direct Access to Quinoline-4-Carboxamides by C-N Bond Cleavage: Cu-Catalyzed Coupling of O -Acyl Oximes with Isatins: Domino Rearrangement Strategy for Direct Access to Quinoline-4-Carboxamides by C-N Bond Cleavage. Eur J Org Chem 2018;2018:2963-71. [DOI: 10.1002/ejoc.201800501] [Cited by in Crossref: 15] [Cited by in F6Publishing: 8] [Article Influence: 3.8] [Reference Citation Analysis]
16 Chan C, Delmonte AJ, Hang C, Hsiao Y, Simmons EM. Development and Scale‐Up of a Palladium‐Catalyzed Intramolecular Direct Arylation in the Commercial Synthesis of Beclabuvir. In: Colacot TJ, Seechurn CCJ, editors. Organometallic Chemistry in Industry. Wiley; 2020. pp. 137-70. [DOI: 10.1002/9783527819201.ch6] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
17 You Y, Kim HS, Park JW, Keum G, Jang SK, Kim BM. Sulfur( vi ) fluoride exchange as a key reaction for synthesizing biaryl sulfate core derivatives as potent hepatitis C virus NS5A inhibitors and their structure–activity relationship studies. RSC Adv 2018;8:31803-21. [DOI: 10.1039/c8ra05471a] [Cited by in Crossref: 5] [Article Influence: 1.3] [Reference Citation Analysis]
18 Chen L, Huang R, Kong LB, Lin J, Yan SJ. Facile Route to the Synthesis of 1,3-Diazahetero-Cycle-Fused [1,2-a]Quinoline Derivatives via Cascade Reactions. ACS Omega 2018;3:1126-36. [PMID: 31457955 DOI: 10.1021/acsomega.7b01856] [Cited by in Crossref: 7] [Cited by in F6Publishing: 2] [Article Influence: 1.8] [Reference Citation Analysis]
19 Young RJ, Leeson PD. Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations. J Med Chem 2018;61:6421-67. [DOI: 10.1021/acs.jmedchem.8b00180] [Cited by in Crossref: 40] [Cited by in F6Publishing: 34] [Article Influence: 10.0] [Reference Citation Analysis]
20 Boldescu V, Behnam MAM, Vasilakis N, Klein CD. Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond. Nat Rev Drug Discov 2017;16:565-86. [PMID: 28473729 DOI: 10.1038/nrd.2017.33] [Cited by in Crossref: 147] [Cited by in F6Publishing: 122] [Article Influence: 29.4] [Reference Citation Analysis]
21 Meng L, Wang Q, Tang T, Xiao S, Zhang L, Zhou D, Yu F. Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Dimers as HCV Entry Inhibitors: Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Dimers as HCV Entry Inhibitors. Chin J Chem 2017;35:1322-8. [DOI: 10.1002/cjoc.201700272] [Cited by in Crossref: 2] [Article Influence: 0.4] [Reference Citation Analysis]
22 Nageswara Rao D, Zephyr J, Henes M, Chan ET, Matthew AN, Hedger AK, Conway HL, Saeed M, Newton A, Petropoulos CJ, Huang W, Kurt Yilmaz N, Schiffer CA, Ali A. Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J Med Chem 2021;64:11972-89. [PMID: 34405680 DOI: 10.1021/acs.jmedchem.1c00554] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
23 Chawner SJ, Cases-Thomas MJ, Bull JA. Divergent Synthesis of Cyclopropane-Containing Lead-Like Compounds, Fragments and Building Blocks through a Cobalt Catalyzed Cyclopropanation of Phenyl Vinyl Sulfide. European J Org Chem 2017;2017:5015-24. [PMID: 28983191 DOI: 10.1002/ejoc.201701030] [Cited by in Crossref: 22] [Cited by in F6Publishing: 11] [Article Influence: 4.4] [Reference Citation Analysis]