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For: Rossi M, Freschi M, de Camargo Nascente L, Salerno A, de Melo Viana Teixeira S, Nachon F, Chantegreil F, Soukup O, Prchal L, Malaguti M, Bergamini C, Bartolini M, Angeloni C, Hrelia S, Soares Romeiro LA, Bolognesi ML. Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease. J Med Chem 2021;64:4972-90. [PMID: 33829779 DOI: 10.1021/acs.jmedchem.1c00048] [Cited by in Crossref: 26] [Cited by in F6Publishing: 29] [Article Influence: 26.0] [Reference Citation Analysis]
Number Citing Articles
1 Li X, Li T, Zhang P, Li X, Lu L, Sun Y, Zhang B, Allen S, White L, Phillips J, Zhu Z, Yao H, Xu J. Discovery of novel hybrids containing clioquinol−1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease. European Journal of Medicinal Chemistry 2022;244:114841. [DOI: 10.1016/j.ejmech.2022.114841] [Reference Citation Analysis]
2 Gujral SS, Shakeri A, Hejazi L, Rao PP. Design, synthesis and structure-activity relationship studies of 3-phenylpyrazino[1,2-a]indol-1(2H)-ones as amyloid aggregation and cholinesterase inhibitors with antioxidant activity. European Journal of Medicinal Chemistry Reports 2022;6:100075. [DOI: 10.1016/j.ejmcr.2022.100075] [Reference Citation Analysis]
3 Pang L, Li J, Liu Z, Quan Y, Sui HH, Jia Y, Chen F, Lee JJ, Liu P, Quan Z, Shen Q, Guo H. In vitro and in vivo biological evaluation of newly synthesized multi-target 20(R)-panaxadiol derivatives for treating Alzheimer's disease. European Journal of Medicinal Chemistry 2022;244:114825. [DOI: 10.1016/j.ejmech.2022.114825] [Reference Citation Analysis]
4 Li HH, Wu C, Zhang SL, Yang JG, Qin HL, Tang W. Fluorosulfate-containing pyrazole heterocycles as selective BuChE inhibitors: structure-activity relationship and biological evaluation for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem 2022;37:2099-111. [PMID: 35899776 DOI: 10.1080/14756366.2022.2103553] [Reference Citation Analysis]
5 Miličević A, Šinko G. Evaluation of the Key Structural Features of Various Butyrylcholinesterase Inhibitors Using Simple Molecular Descriptors. Molecules 2022;27:6894. [PMID: 36296489 DOI: 10.3390/molecules27206894] [Reference Citation Analysis]
6 Jastrzębska-więsek M, Kotańska M, Grzeszczak A, Jaromin A, Walczak M, Partyka A, Gdula-argasińska J, Smolik M, Zagórska A. The Antidepressant-like Activity, Effects on Recognition Memory Deficits, Bioavailability, and Safety after Chronic Administration of New Dual-Acting Small Compounds Targeting Neuropsychiatric Symptoms in Dementia. IJMS 2022;23:11452. [DOI: 10.3390/ijms231911452] [Reference Citation Analysis]
7 Liu W, Zhao D, He Z, Hu Y, Zhu Y, Zhang L, Jin L, Guan L, Wang S. Synthesis and Biological Activity Evaluation of Benzothiazole-isoquinoline Derivatives.. [DOI: 10.21203/rs.3.rs-2004488/v1] [Reference Citation Analysis]
8 Arrué L, Cigna-Méndez A, Barbosa T, Borrego-Muñoz P, Struve-Villalobos S, Oviedo V, Martínez-García C, Sepúlveda-Lara A, Millán N, Márquez Montesinos JCE, Muñoz J, Santana PA, Peña-Varas C, Barreto GE, González J, Ramírez D. New Drug Design Avenues Targeting Alzheimer's Disease by Pharmacoinformatics-Aided Tools. Pharmaceutics 2022;14:1914. [PMID: 36145662 DOI: 10.3390/pharmaceutics14091914] [Reference Citation Analysis]
9 Carocci A, Barbarossa A, Leuci R, Carrieri A, Brunetti L, Laghezza A, Catto M, Limongelli F, Chaves S, Tortorella P, Altomare CD, Santos MA, Loiodice F, Piemontese L. Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease. Antioxidants 2022;11:1631. [DOI: 10.3390/antiox11091631] [Reference Citation Analysis]
10 Elumalai V, Trobec T, Grundner M, Labriere C, Frangež R, Sepčić K, Hansen JH, Svenson J. Development of potent cholinesterase inhibitors based on a marine pharmacophore. Org Biomol Chem 2022;20:5589-601. [PMID: 35796650 DOI: 10.1039/d2ob01064j] [Reference Citation Analysis]
11 Kumari S, Maddeboina K, Bachu RD, Boddu SHS, Trippier PC, Tiwari AK. Pivotal role of nitrogen heterocycles in Alzheimer's disease drug discovery. Drug Discov Today 2022:S1359-6446(22)00292-6. [PMID: 35868626 DOI: 10.1016/j.drudis.2022.07.007] [Reference Citation Analysis]
12 Dame-Teixeira N, El-Gendy R, Monici Silva I, Holanda CA, de Oliveira AS, Romeiro LAS, Do T. Sustainable multifunctional phenolic lipids as potential therapeutics in Dentistry. Sci Rep 2022;12:9299. [PMID: 35662265 DOI: 10.1038/s41598-022-13292-0] [Reference Citation Analysis]
13 Fernández-Bolaños JG, López Ó. Butyrylcholinesterase inhibitors as potential anti-Alzheimer's agents: an updated patent review (2018-present). Expert Opin Ther Pat 2022. [PMID: 35623095 DOI: 10.1080/13543776.2022.2083956] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
14 Maciejewska K, Czarnecka K, Kręcisz P, Niedziałek D, Wieczorek G, Skibiński R, Szymański P. Novel Cyclopentaquinoline and Acridine Analogs as Multifunctional, Potent Drug Candidates in Alzheimer's Disease. Int J Mol Sci 2022;23:5876. [PMID: 35682556 DOI: 10.3390/ijms23115876] [Reference Citation Analysis]
15 Ismaili L, Bernard PJ, Refouvelet B. Latest progress in the development of multitarget ligands for Alzheimer's disease based on the Hantzsch reaction. Future Med Chem 2022. [PMID: 35608057 DOI: 10.4155/fmc-2022-0080] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
16 Jansa P, Barvík I, Hulcová D, Matoušová E. Synthesis and cholinesterase inhibitory activity study of Amaryllidaceae alkaloid analogues with N-methyl substitution. Org Biomol Chem 2022;20:3960-6. [PMID: 35471452 DOI: 10.1039/d2ob00553k] [Reference Citation Analysis]
17 Guo J, Xu A, Cheng M, Wan Y, Wang R, Fang Y, Jin Y, Xie S, Liu J. Design, Synthesis and Biological Evaluation of New 3,4-Dihydro-2(1H)-Quinolinone-Dithiocarbamate Derivatives as Multifunctional Agents for the Treatment of Alzheimer’s Disease. DDDT 2022;Volume 16:1495-1514. [DOI: 10.2147/dddt.s354879] [Reference Citation Analysis]
18 Araujo de Oliveira AP, Romero Colmenares VC, Diniz R, Freitas JTJ, da Cruz CM, Lages EB, Ferreira LAM, Vieira RP, Beraldo H. Memantine-Derived Schiff Bases as Transdermal Prodrug Candidates. ACS Omega 2022;7:11678-87. [PMID: 35449959 DOI: 10.1021/acsomega.1c06571] [Reference Citation Analysis]
19 Codony S, Pont C, Griñán-Ferré C, Di Pede-Mattatelli A, Calvó-Tusell C, Feixas F, Osuna S, Jarné-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Pérez B, Bartra C, Sanfeliu C, Juárez-Jiménez J, Morisseau C, Hammock BD, Pallàs M, Vázquez S, Muñoz-Torrero D. Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem 2022. [PMID: 35271276 DOI: 10.1021/acs.jmedchem.1c02150] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 4.0] [Reference Citation Analysis]
20 Sahin C, Magomedova L, Ferreira TAM, Liu J, Tiefenbach J, Alves PS, Queiroz FJG, Oliveira AS, Bhattacharyya M, Grouleff J, Nogueira PCN, Silveira ER, Moreira DC, Leite JRSA, Brand GD, Uehling D, Poda G, Krause H, Cummins CL, Romeiro LAS. Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases. J Med Chem 2022. [PMID: 35089724 DOI: 10.1021/acs.jmedchem.1c01542] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
21 Somjai C, Siriwoharn T, Kulprachakarn K, Chaipoot S, Phongphisutthinant R, Chaiyana W, Srinuanpan S, Wiriyacharee P. Effect of drying process and long-term storage on characterization of Longan pulps and their biological aspects: Antioxidant and cholinesterase inhibition activities. LWT 2022;154:112692. [DOI: 10.1016/j.lwt.2021.112692] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 3.0] [Reference Citation Analysis]
22 Li X, Li J, Huang Y, Gong Q, Fu Y, Xu Y, Huang J, You H, Zhang D, Zhang D, Mao F, Zhu J, Wang H, Zhang H, Li J. The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression. Eur J Med Chem 2021;229:114045. [PMID: 34922191 DOI: 10.1016/j.ejmech.2021.114045] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
23 Pont C, Ginex T, Griñán-Ferré C, Scheiner M, Mattellone A, Martínez N, Arce EM, Soriano-Fernández Y, Naldi M, De Simone A, Barenys M, Gómez-Catalán J, Pérez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallàs M, Luque FJ, Muñoz-Torrero D. From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects. Eur J Med Chem 2021;225:113779. [PMID: 34418785 DOI: 10.1016/j.ejmech.2021.113779] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 4.0] [Reference Citation Analysis]
24 Bakare OO, Fadaka AO, Akanbi MO, Akinyede KA, Klein A, Keyster M. Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for 'Alzheimer's disease: an in silico approach. BMC Mol Cell Biol 2021;22:49. [PMID: 34592924 DOI: 10.1186/s12860-021-00386-2] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
25 Bisenieks E, Vigante B, Petrovska R, Turovska B, Muhamadejev R, Soloduns V, Velena A, Pajuste K, Saso L, Klovins J, Duburs G, Mandrika I. The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A. Pharmaceuticals (Basel) 2021;14:987. [PMID: 34681211 DOI: 10.3390/ph14100987] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
26 Dong Q, Wu Y. Research on Risk Assessment of Multitarget Wireless Sensing Detection Auxiliary Engineering in Mine Geological Environment. Journal of Sensors 2021;2021:1-11. [DOI: 10.1155/2021/9915430] [Reference Citation Analysis]
27 Gonçalves PB, Sodero ACR, Cordeiro Y. Green Tea Epigallocatechin-3-gallate (EGCG) Targeting Protein Misfolding in Drug Discovery for Neurodegenerative Diseases. Biomolecules 2021;11:767. [PMID: 34065606 DOI: 10.3390/biom11050767] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 14.0] [Reference Citation Analysis]